Experimental Study on the Oral Gangrene Appearing in Takahara's Disease Part Ⅱ Effect of a Few Cocci on the Acatalasemic Blood and Normal Blood

As described in Part 1, by injecting Diplococcus pneumoniae which generates hydrogen peroxide under the mucous membrane of the palate of duck, there appeared pathological changes in duck palate resembling macroscopically and microscopically the findings observed in acatalasemia cases. Being without definite conclusion on the point of action mechanism of hydrogen peroxide, it was assumed that the changes in duck palate were caused by hydrogen peroxide generated by the cocci. To illustrate the point of action mechanism of hydrogen peroxide and the etiology of Takahara's disease the degradation of oxyhemoglobin and the methemoglobin-formation in culture of these cocci supplemented with duck blood, rabbit blood, acatalasemic blood or normal human blood were investigated by the following methods in each chapter.