The effct of ATP on excretion of BSP in liver disease

BSP retention and hepatic blood flow were determined after administration of ATP in liver disease, and the following results were obtained. 1) 14 cases out of 22 with liver disease having, administration of ATP improved in BSP retention, and on the other hand, 8 cases of the remainder showed no changes or aggravation in that test. 2) Considerable grade of hepatic cell degeneration or necrosis was found in liver biopsy tissue of the all aggravating cases. 3) After the intravenous injection of ATP hepatic blcod flow decreased temporarily and was followed subsequently by an increase.