Influences of ATP on Hematopoietic Functions of Bone Marrow 3. Influences of ATP on Erythropoietic Functions of Rabbit, Normal Human and Hypoplastic Marrow

For the purpose of observing the influences of ATP on the bone marrow erythropoiesis, a roller tube culture method was used to cultivate bone marrow cell suspensions from normal rabbits, normal persons and patients with hypoplastic anemia. ATP solutions at various concentrations were added directly to the culture media and observations were carried out. As a result, it has been shown that addition of ATP resulted in an increase of erythrocytes, increase of hemoglobin content and increasing percentage of orthochromic erythroblasts.