Influences of ATP on Hematopoietic Functions of Bone Marrow 2. Influences of ATP on Thrombopoietic Functions of Guinea Pig, Normal Human and Hypoplastic Marrow

In order to observe the influences of ATP on the bone marrow thrombopoiesis, clinical tissue culture of bone marrow from normal guinea pigs, normal persons and patients with hypoplastic anemia was conducted. ATP solutions at various concentrations were added directly to the culture media and observations were carried out to see effect of ATP on the functions of megakaryocytes of bone marrow. As a result, it has been seen that by adding an optimal amount of ATP the functions of megakaryocytes were accelerated.