Experimental studies on pyruvate metabolism in rabbits' brain by irrigation method. Part 2. On influences of Co-factor of pyruvic decarboxylase upon pyruvate metabolism in normal rabbit's brain

The amounts of the pyruvate and the citrate in the irrigating fluid were measured before and after irrigation of rabbit's brain with pyruvate-added fluid, and TPP, CoA, DPN, oxalacetate or biotin was added to the experiment. Each of these substances proved to accelerate pyruvate oxydation as well as citrate formation.