Studies on the Anticonvulsive effects of Diamox Part Ⅲ. The Effects of Diamox on the Cholinesterase Activities in the Brain

The effects of Diamox on the cholinesterase activities in nucleus lenticularis of cats brain were measured. The experiments were performed by Ammon method taking the sanples at 9 and 24 hours respectively after the injection of Diamox. Concerning about the mean values of each 7 cases, the cholinesterase activities showed 44.8% increase at 9 hours and 43.4% increase at 24 hours. The anticonvulsive effects of Diamox were considered to be caused by the acceleration of the acetylcholin decomposition of cholinesterase from these experimental results.