HISTOLOGIC CHANGES OF THE SALIVARY GLANDS IN THE EXPERIMENTAL POISONING BY CALCIUM DISULFIDE AND EFFECTS OF VARIOUS VITAMINS ON THE CHANGES

Histologic observations were made on the lesions of the salivary glands of mice caused by calcium disulphide poisoning, and the effects of various vitamins, A, B, C and D, on these changes were investigated. The results are briefly summarized as follows: 1. In the parotid glands, the gland cells showed marked atrophy with the decrease of secretion glanules in number. The epithelium of the striated tubules increased in its height, the striae becoming more distinct. 2. In the submaxillar glands, the gland cells showed high degree of atrophy, the reticular structure becoming less distinct. The epithelium of the striated tubules decreased in its height, the striae also becoming less distinct. The epithelium of the granular striated tubules showed marked atrophy with the decrease of the granules in number. 3. The administration of various vitamins reduced the lesions in both the parotid and submaxillar glands caused by carbon disulphide poisoning. 4. As regards the effects of vitamins, V. C produced the most remarkable one, and V. D as well as V. B, moderate, and V. A, the least powerful, though, as a matter of fact, it is hard to make clear-cut distinction between them.