Studies on the Effect of Cancer on the Pituitary-Adrenocortical System Part IV. The Effect of Cancer on ACTH-, and epinephrine-eosinopenia. (Thorn's Test)

The author performed Thorn's tests with ACTH and epinephrine on mice inoculated with cancerous materials, and the following results were obtained: 1. Thorn's tests in mice with transplanted mammary cancer and those injected with cancer tissue extract or urine from cancer patients showed negative results. 2. The products of cancer tissues are regarded to decrease adrenocortical reserve function as a result of the stimulation the pituitary-adrenocortical system.