Journal of Okayama Medical Association
Published by Okayama Medical Association

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術前化学療法により壁が菲薄化し組織学的寛解(pCR)となった巨大嚢胞内乳癌の1例

Imada, Takako
Matsuoka, Junji Kaken ID researchmap
Motoki, Takayuki publons
Iwamoto, Takayuki
Oomori, Masako
Iha, Sigemichi
Hongo, Toshie
Henmi, Noriko
Makabe, Mikio
Nogami, Hiromi
124_243.pdf 4.92 MB
Abstract
 A 31-year-old woman presented to our hospital because of a lump 5cm in diameter in her right breast. Ultrasonography revealed a multilocular cystic mass with partial thickening of the wall and the septum. Core needle biopsy (CNB) of the septum confirmed invasive ductal carcinoma. The patient was administered neoadjuvant chemotherapy consisting of 12 cycles of weekly paclitaxel followed by 4 cycles of FEC (5FU, Epilubicin and cyclophosphamide). While the thickness of the wall and septum became thinner, the tumor size did not change in diameter. She underwent right mastectomy and sentinel node biopsy. Post-surgical histopathological findings showed a pathological complete response (pCR).
 We report a rare case of invasive ductal carcinoma presenting a multilobular phenotype which showed pCR by neoadjuvant chemotherapy despite no size reduction of the tumor.
Keywords
嚢胞内乳癌(intracystic breast cancer)
術前化学療法(neoadjuvant chemotherapy)
組織学的完全奏功(pahthological CR)
Note
症例報告(Case Report)
ISSN
0030-1558
NCID
AN00032489
DOI