Bulletin of Faculty of Health Sciences Okayama University Medical School
Published by Faculty of Health Sciences Okayama University Medical School

<Formerly known as>
岡山大学医療技術短期大学部紀要 (1巻-9巻)

ヘミンの酸化開裂によるプロペイトダイオペントの合成

Hirota, Kazuhiro
Abstract
The methanol adduct of dimethyl ester of propentdyopent, which have two carboxyl groups on two pyrrole rings, was prepared by the oxidation of hemin with hydrogen peroxide and following esterification with a mixture of methanol and sulfuric acid. The compound was purified by the preparative column chromatography with silica gel and following recrystallization. The purity was checked by thin-layer chromatography and high-performance liquid chromatography. The compound was identified with mass and nuclear magnetic resonance spectra.
Keywords
pentdyopent
dipyrrole
hemin
hydrogen peroxide
ISSN
0917-4494
NCID
AN10355371