Acta Medica Okayama volume74 issue5
2020-10 発行

Study Protocol for Assessing the Efficacy of Compression Therapy Using Stockings and Sleeves to Prevent Docetaxel-Induced Peripheral Neuropathy in Breast Cancer Patients

Yamanouchi, Kosho Department of Surgery, Nagasaki University Graduate School of Biomedical Science
Kuba, Sayaka Department of Surgery, Nagasaki University Graduate School of Biomedical Science
Matsumoto, Megumi Department of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science
Yano, Hiroshi Department of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science
Morita, Michi Department of Surgery, Nagasaki University Graduate School of Biomedical Science
Sakimura, Chika Department of Surgery, Nagasaki University Graduate School of Biomedical Science
Otsubo, Ryota Department of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science
Kanetaka, Kengo Department of Surgery, Nagasaki University Graduate School of Biomedical Science
Nagayasu, Takeshi Department of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science
Eguchi, Susumu Department of Surgery, Nagasaki University Graduate School of Biomedical Science
Publication Date
2020-10
Abstract
Taxanes are key drugs for patients with breast cancer. A major adverse effect associated with the administration of the taxane docetaxel is chemotherapy-induced peripheral neuropathy (CIPN). We are conducting a singlecenter, single-arm, open-label historical control trial to evaluate the ability of compression therapy using stockings or sleeves to prevent CIPN due to docetaxel treatment. The primary endpoint is the incidence of all-grade CIPN according to patients’ records until 3 weeks after the fourth docetaxel administration. This study’s results will clarify whether compression therapy using stockings or sleeves can prevent CIPN in breast cancer patients.
Document Type
Clinical Study Protocol
Keywords
breast cancer
docetaxel
neuropathy
compression
Link to PubMed
74_5_455.pdf 1.93 MB