start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2025
dt-pub=20250325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=分布型光ファイバセンシング技術を用いた河川堤防の浸透流速および越水による破壊プロセスのモニタリングに関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FUJIIHirokazu
en-aut-sei=FUJII
en-aut-mei=Hirokazu
kn-aut-name=藤井宏和
kn-aut-sei=藤井
kn-aut-mei=宏和
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=岡山大学大学院環境生命科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2025
dt-pub=20250519
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Novel method of leukocytapheresis using a highly concentrated sodium citrate solution alternative to acid citrate dextrose solution A
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Background: Large-volume leukocytapheresis is time consuming. The upper limit of the inlet flow rate is determined by the inlet: anticoagulant (AC) ratio and can be changed by combining the AC with heparin. Here, we devised a protocol to increase the AC ratio using a highly concentrated sodium citrate solution without heparin.<br>
Study Design and Methods: We collected data from 40 consecutive apheresis procedures performed using the Spectra Optia system on 40 donors for allogeneic peripheral blood stem cells between June 2022 and June 2023. We used AC containing 2.2% sodium citrate (normal concentrated sodium citrate [NSC]) and 5.32% sodium citrate (highly concentrated sodium citrate [HSC]). The AC ratios were set to 12:1 and 24:1 for the NSC and HSC, respectively.<br>
Results: The processed volume was not different; the maximum inlet flow rate increased, the total processing time was reduced, the AC solution used was reduced, and the product volume was reduced in the HSC group, compared to the NSC group. Although the CD34+ cell CE2 was reduced in the HSC group, no difference was observed in the number of collected CD34+ cells. The incidences of citrate-related reactions were similar.<br>
Discussion: We propose a novel leukocytapheresis method using HSC that shortens the procedure time and reduces the amount of AC solution used compared to the conventional method
en-copyright=
kn-copyright=

en-aut-name=AbeMasaya
en-aut-sei=Abe
en-aut-mei=Masaya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=FujiiKeiko
en-aut-sei=Fujii
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=MitsuhashiToshiharu
en-aut-sei=Mitsuhashi
en-aut-mei=Toshiharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=KitamuraWataru
en-aut-sei=Kitamura
en-aut-mei=Wataru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=IkeuchiKazuhiro
en-aut-sei=Ikeuchi
en-aut-mei=Kazuhiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=FukumiTakuya
en-aut-sei=Fukumi
en-aut-mei=Takuya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=WashioKana
en-aut-sei=Washio
en-aut-mei=Kana
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=OtsukaFumio
en-aut-sei=Otsuka
en-aut-mei=Fumio
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

affil-num=1
en-affil=Division of Transfusion and Cell Therapy, Okayama University Hospital
kn-affil=

affil-num=2
en-affil=Division of Clinical Laboratory, Okayama University Hospital
kn-affil=

affil-num=3
en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital
kn-affil=

affil-num=4
en-affil=Division of Transfusion and Cell Therapy, Okayama University Hospital
kn-affil=

affil-num=5
en-affil=Division of Transfusion and Cell Therapy, Okayama University Hospital
kn-affil=

affil-num=6
en-affil=Division of Transfusion and Cell Therapy, Okayama University Hospital
kn-affil=

affil-num=7
en-affil=Department of Pediatric Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=8
en-affil=Division of Clinical Laboratory, Okayama University Hospital
kn-affil=

affil-num=9
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=10
en-affil=Division of Transfusion and Cell Therapy, Okayama University Hospital
kn-affil=
en-keyword=anticoagulant
kn-keyword=anticoagulant
en-keyword=apheresis
kn-keyword=apheresis
en-keyword=high sodium citrate concentration
kn-keyword=high sodium citrate concentration
en-keyword=Spectra Optia
kn-keyword=Spectra Optia
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2025
dt-pub=20250224
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=A randomized controlled trial of conventional GVHD prophylaxis with or without teprenone for the prevention of severe acute GVHD
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Therapies that effectively suppress graft-versus-host disease (GVHD) without compromising graft-versus-leukemia/lymphoma (GVL) effects is important in allogeneic hematopoietic stem cell transplantation (allo-HSCT) for hematopoietic malignancies. Geranylgeranylacetone (GGA) is a main component of teprenone, a gastric mucosal protectant commonly used in clinical practice. In preclinical models, GGA suppresses proinflammatory cytokines, including interleukin (IL)-1β, IL-6, and tumor necrosis factor-α (TNF-α), which are associated with GVHD as well as induces thioredoxin-1 (Trx-1), which suppresses GVHD while maintaining GVL effects. Here, we investigated whether the addition of teprenone to standard GVHD prophylaxis could reduce the cumulative incidence of severe acute GVHD (aGVHD) without attenuating GVL effects. This open-label, randomized clinical trial enrolled 40 patients (21 control and 19 teprenone group) who received allo-HSCT between May 2022 and February 2023 in our institution. Patients in the teprenone group received 50 mg of teprenone orally thrice daily for 21 days from the initiation of the conditioning regimen. The cumulative incidence of severe aGVHD by day 100 after allo-HSCT was not significantly different in the two groups (27.9 vs. 16.1%, p?=?0.25). The exploratory studies revealed no obvious changes in Trx-1 levels, but the alternations from baseline in IL-1β and TNF-α levels at day 28 after allo-HSCT tended to be lower in the teprenone group. In conclusion, we could not demonstrate that teprenone significantly prevented the development of severe aGVHD. Discrepancy with preclinical model suggests that appropriate dose of teprenone may be necessary to induce the expression of antioxidant enzymes that suppress severe aGVHD. Clinical Trial Registration number:jRCTs 061210072.
en-copyright=
kn-copyright=

en-aut-name=KitamuraWataru
en-aut-sei=Kitamura
en-aut-mei=Wataru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=FujiiKeiko
en-aut-sei=Fujii
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=TsugeMitsuru
en-aut-sei=Tsuge
en-aut-mei=Mitsuru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=MitsuhashiToshiharu
en-aut-sei=Mitsuhashi
en-aut-mei=Toshiharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=KobayashiHiroki
en-aut-sei=Kobayashi
en-aut-mei=Hiroki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=KamoiChihiro
en-aut-sei=Kamoi
en-aut-mei=Chihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=YamamotoAkira
en-aut-sei=Yamamoto
en-aut-mei=Akira
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=KondoTakumi
en-aut-sei=Kondo
en-aut-mei=Takumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=SeikeKeisuke
en-aut-sei=Seike
en-aut-mei=Keisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=FujiwaraHideaki
en-aut-sei=Fujiwara
en-aut-mei=Hideaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=AsadaNoboru
en-aut-sei=Asada
en-aut-mei=Noboru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=EnnishiDaisuke
en-aut-sei=Ennishi
en-aut-mei=Daisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=MatsuokaKen-ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=

affil-num=1
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=2
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=3
en-affil=Department of Pediatric Acute Diseases, Okayama University Academic Field of Medicine Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=4
en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital
kn-affil=

affil-num=5
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=6
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=7
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=8
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=9
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=10
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=11
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=12
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=13
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=14
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=15
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=
en-keyword=Allogeneic hematopoietic stem cell transplantation
kn-keyword=Allogeneic hematopoietic stem cell transplantation
en-keyword=Graft-versus-host disease
kn-keyword=Graft-versus-host disease
en-keyword=Teprenone
kn-keyword=Teprenone
en-keyword=Oxidative stress
kn-keyword=Oxidative stress
en-keyword=Interleukin-33
kn-keyword=Interleukin-33
END

start-ver=1.4
cd-journal=joma
no-vol=145
cd-vols=
no-issue=8
article-no=
start-page=881
end-page=896
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2025
dt-pub=20250220
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Oral Inflammation and Microbiome Dysbiosis Exacerbate Chronic Graft-versus-host Disease
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The oral microbiota, second in abundance to the gut, is implicated in chronic systemic diseases, but its specific role in graft-versus-host disease (GVHD) pathogenesis has been unclear. Our study finds that mucositis-induced oral dysbiosis in patients after hematopoietic cell transplantation (HCT) associated with increased chronic GVHD (cGVHD), even in patients receiving posttransplant cyclophosphamide. In murine HCT models, oral dysbiosis caused by bilateral molar ligatures exacerbated cGVHD and increased bacterial load in the oral cavity and gut, with Enterococcaceae significantly increasing in both organs. In this model, the migration of Enterococcaceae to cervical lymph nodes both before and after transplantation activated antigen-presenting cells, thereby promoting the expansion of donor-derived inflammatory T cells. Based on these results, we hypothesize that pathogenic bacteria increase in the oral cavity might not only exacerbate local inflammation but also enhance systemic inflammation throughout the HCT course. Additionally, these bacteria translocated to the gut and formed ectopic colonies, further amplifying systemic inflammation. Furthermore, interventions targeting the oral microbiome mitigated murine cGVHD. Collectively, our findings highlight the importance of oral dysbiosis in cGVHD and suggest that modulation of the oral microbiome during transplantation may be an effective approach for preventing or treating cGVHD.
en-copyright=
kn-copyright=

en-aut-name=KambaraYui
en-aut-sei=Kambara
en-aut-mei=Yui
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=FujiwaraHideaki
en-aut-sei=Fujiwara
en-aut-mei=Hideaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=YamamotoAkira
en-aut-sei=Yamamoto
en-aut-mei=Akira
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=GotohKazuyoshi
en-aut-sei=Gotoh
en-aut-mei=Kazuyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=TsujiShuma
en-aut-sei=Tsuji
en-aut-mei=Shuma
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=KunihiroMari
en-aut-sei=Kunihiro
en-aut-mei=Mari
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=OyamaTadashi
en-aut-sei=Oyama
en-aut-mei=Tadashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=TeraoToshiki
en-aut-sei=Terao
en-aut-mei=Toshiki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=SatoAyame
en-aut-sei=Sato
en-aut-mei=Ayame
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=TanakaTakehiro
en-aut-sei=Tanaka
en-aut-mei=Takehiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=PeltierDaniel
en-aut-sei=Peltier
en-aut-mei=Daniel
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=SeikeKeisuke
en-aut-sei=Seike
en-aut-mei=Keisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=NishimoriHisakazu
en-aut-sei=Nishimori
en-aut-mei=Hisakazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

en-aut-name=AsadaNoboru
en-aut-sei=Asada
en-aut-mei=Noboru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=

en-aut-name=EnnishiDaisuke
en-aut-sei=Ennishi
en-aut-mei=Daisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=

en-aut-name=FujiiKeiko
en-aut-sei=Fujii
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=16
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=17
ORCID=

en-aut-name=MatsuokaKen-ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=18
ORCID=

en-aut-name=SogaYoshihiko
en-aut-sei=Soga
en-aut-mei=Yoshihiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=19
ORCID=

en-aut-name=ReddyPavan
en-aut-sei=Reddy
en-aut-mei=Pavan
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=20
ORCID=

en-aut-name=YoshinobuMaeda
en-aut-sei=Yoshinobu
en-aut-mei=Maeda
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=21
ORCID=

affil-num=1
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Medical School
kn-affil=

affil-num=2
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=3
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=4
en-affil=Department of Medical Laboratory Science, Okayama University Graduate School of Health Sciences
kn-affil=

affil-num=5
en-affil=Department of Microbiology and Genetics, Okayama University Graduate School of Health Sciences
kn-affil=

affil-num=6
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=7
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=8
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=9
en-affil=Division of Hospital Dentistry, Okayama University Hospital
kn-affil=

affil-num=10
en-affil=Department of Pathology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=11
en-affil=Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation, Department of Pediatrics, Herman B Wells Center for Pediatric Research, Simon Cancer Center, Indiana University School of Medicine
kn-affil=

affil-num=12
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=13
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=14
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=15
en-affil=Center for Comprehensive Genomic Medicine, Okayama University Hospital
kn-affil=

affil-num=16
en-affil=Department of Clinical Laboratory, Okayama University Hospital
kn-affil=

affil-num=17
en-affil=Division of Blood Transfusion, Okayama University Hospital
kn-affil=

affil-num=18
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=19
en-affil=Division of Hospital Dentistry, Okayama University Hospital
kn-affil=

affil-num=20
en-affil=Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine
kn-affil=

affil-num=21
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=56
cd-vols=
no-issue=2
article-no=
start-page=1
end-page=16
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=20241125
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Why Is Intermediate Organization Necessary?
kn-title=なぜ中間組織が必要なのか
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=　This paper challenges a fundamental question, ‘Why is an intermediate organization necessary?’ Due to transaction costs and market failures on the one hand and the limitations of organizational control mechanisms on the other hand, many‘ intermediate organizations’ are observed in the real world. How can we tackle to explain the governance mechanism considered to be‘ intermediate?’
　If we are to discuss such socioeconomic orders, this paper assumes that we should not be able to link micro-level explanations and macro-level ones concerning the third mode of governance mechanisms all at once. We need to stick to the meso-level at fi rst. The theoretical elaboration since Ouchi’s（1980） discussion of clan-type governance and cumulative empirical research on industrial agglomerations have allowed us to construct a more sophisticated theory called community capital.
　In effective communities, members are ‘embedded as insiders’ who serve the purpose of the community, share experiences of failures and successes, and find and deepen their common identity. This limited membership is bound by‘ mutual trust to rely on each other’ for‘ distribution of short-term risks.’ In contrast to social norms that need to be abstract enough to be widely shared, the communal norms that are concrete enough to allow the members to understand without hesitation how they should behave in localized contexts are cumulatively cultivated along socializing process. Among the norms, sense of mutual obligation to incur intermittent costs for the whole community is a crucial norm for the sustainable development of the community. However, as a practical matter, membership control, mutual trust and short-term risk allocation may serve the communities in the short run, but they do not guarantee long-term accumulation of shared capital. As a result, the limits of community capital may need to be discussed once again, especially today when market liquidity is increasing, and its failures tend to become more apparent in a variety of areas.
en-copyright=
kn-copyright=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=1
ORCID=

en-aut-name=OshimaTamako
en-aut-sei=Oshima
en-aut-mei=Tamako
kn-aut-name=大島珠子
kn-aut-sei=大島
kn-aut-mei=珠子
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学学術研究院ヘルスシステム統合科学学域

affil-num=2
en-affil=
kn-affil=国際医療福祉大学小田原保健医療学部看護学科
en-keyword=中間組織
kn-keyword=中間組織
en-keyword=内部組織の経済学
kn-keyword=内部組織の経済学
en-keyword=産業集積
kn-keyword=産業集積
en-keyword=コミュニティ・キャピタル
kn-keyword=コミュニティ・キャピタル
END

start-ver=1.4
cd-journal=joma
no-vol=51
cd-vols=
no-issue=
article-no=
start-page=102104
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=2024
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Protracted coronavirus disease 2019 after chimeric antigen receptor-T cell therapy successfully treated with sequential multidrug therapy
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 56-year-old woman who received CD19 chimeric antigen receptor-T cell therapy for refractory diffuse large B-cell lymphoma developed severe coronavirus disease 2019 (COVID-19) and was treated with nirmatrelvir/ritonavir in April 2022. However, she experienced persistent fatigue and cough and fever in June. Computed tomography revealed bilateral ground-glass opacities (GGO), and the patient was treated with corticosteroids for organizing pneumonia after COVID19. Partial improvement was observed, but new GGO appeared despite corticosteroid therapy. Genome analysis of severe acute respiratory syndrome coronavirus 2 detected Omicron variant BA.1.1.2, which was prevalent at the time of initial infection. The patient was diagnosed with protracted COVID-19 and was treated with remdesivir, molnupiravir, nirmatrelvir/ritonavir, and tixagevimab/cilgavimab. These treatments appeared to contribute to the improvement of protracted COVID-19.
en-copyright=
kn-copyright=

en-aut-name=YamashitaMasahiro
en-aut-sei=Yamashita
en-aut-mei=Masahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=HigoHisao
en-aut-sei=Higo
en-aut-mei=Hisao
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=MatsumotoChiaki
en-aut-sei=Matsumoto
en-aut-mei=Chiaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=MakimotoGo
en-aut-sei=Makimoto
en-aut-mei=Go
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=NinomiyaKiichiro
en-aut-sei=Ninomiya
en-aut-mei=Kiichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=FujiiMasanori
en-aut-sei=Fujii
en-aut-mei=Masanori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=RaiKammei
en-aut-sei=Rai
en-aut-mei=Kammei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=IchiharaEiki
en-aut-sei=Ichihara
en-aut-mei=Eiki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=OhashiKadoaki
en-aut-sei=Ohashi
en-aut-mei=Kadoaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=HottaKatsuyuki
en-aut-sei=Hotta
en-aut-mei=Katsuyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=TabataMasahiro
en-aut-sei=Tabata
en-aut-mei=Masahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

en-aut-name=MiyaharaNobuaki
en-aut-sei=Miyahara
en-aut-mei=Nobuaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=

affil-num=1
en-affil=Department of Allergy and Respiratory Medicine, Okayama University Hospital
kn-affil=

affil-num=2
en-affil=Department of Allergy and Respiratory Medicine, Okayama University Hospital
kn-affil=

affil-num=3
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=4
en-affil=Department of Allergy and Respiratory Medicine, Okayama University Hospital
kn-affil=

affil-num=5
en-affil=Department of Allergy and Respiratory Medicine, Okayama University Hospital
kn-affil=

affil-num=6
en-affil=Center for Comprehensive Genomic Medicine, Okayama University Hospital
kn-affil=

affil-num=7
en-affil=Department of Allergy and Respiratory Medicine, Okayama University Hospital
kn-affil=

affil-num=8
en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital
kn-affil=

affil-num=9
en-affil=Center for Clinical Oncology, Okayama University Hospital
kn-affil=

affil-num=10
en-affil=Department of Allergy and Respiratory Medicine, Okayama University Hospital
kn-affil=

affil-num=11
en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital
kn-affil=

affil-num=12
en-affil=Center for Clinical Oncology, Okayama University Hospital
kn-affil=

affil-num=13
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=14
en-affil=Department of Allergy and Respiratory Medicine, Okayama University Hospital
kn-affil=
en-keyword=Chimeric antigen receptor-T cell therapy
kn-keyword=Chimeric antigen receptor-T cell therapy
en-keyword=Coronavirus disease 2019
kn-keyword=Coronavirus disease 2019
en-keyword=Multidrug therapy
kn-keyword=Multidrug therapy
en-keyword=Organizing pneumonia
kn-keyword=Organizing pneumonia
END

start-ver=1.4
cd-journal=joma
no-vol=22
cd-vols=
no-issue=5
article-no=
start-page=253
end-page=266
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=20240509
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Freeze-thaw Resistance of Concrete using Ground Granulated Blast-furnace Slag and Blast-furnace Slag Sand in Salt Water
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The freeze-thaw resistance of concrete is significantly lower in salt water than in fresh water. Concrete deteriorates through repeated freezing and thawing, but in salt water, freezing alone leads to destruction. This paper investigated the effect of calcium hydroxide in concrete on the failure of concrete under such low temperatures. Calcium hydroxide precipitates at the transition zone between aggregate and cement paste due to the hydration of cement. The lower the temperature and the higher the concentration of salt water, the more calcium hydroxide dissolves. From concrete, more calcium hydroxide is eluted in salt water than in fresh water. This accelerates the deterioration of mortar and concrete due to freeze-thaw action. Mortar and concrete using ground granulated blast-furnace slag produces less calcium hydroxide. In mortar and concrete using blast-furnace slag sand, calcium hydroxide precipitated around the aggregate reacts with cement paste and blast-furnace slag sand to modify the transition zone. From these results, it was clarified that concrete using blast-furnace slag exhibits high freeze-thaw resistance even in salt water.<br>
This paper is the English translation of the authors’ previous work [Ayano, T., Fujii, T. and Okazaki, K., (2023). “Freeze-thaw resistance of concrete using ground granulated blast-furnace and blast-furnace slag sand in salt water.” Japanese Journal of JSCE, 79(12), 23-00042. (in Japanese)].
en-copyright=
kn-copyright=

en-aut-name=AyanoToshiki
en-aut-sei=Ayano
en-aut-mei=Toshiki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=FujiiTakashi
en-aut-sei=Fujii
en-aut-mei=Takashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=OkazakiKanako
en-aut-sei=Okazaki
en-aut-mei=Kanako
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

affil-num=1
en-affil=Faculty of Environmental, Life, Natural Science and Technology, Okayama University
kn-affil=

affil-num=2
en-affil=Faculty of Environmental, Life, Natural Science and Technology, Okayama University
kn-affil=

affil-num=3
en-affil=Division of Social Engineering and Environmental Management, Graduate School of Environmental and Life Science, Okayama University
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=5
cd-vols=
no-issue=4
article-no=
start-page=810
end-page=814
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=20240619
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Combination of reduced post-transplant cyclophosphamide and early tacrolimus initiation increases the incidence of chronic graft-versus-host disease in human leukocyte antigen-haploidentical peripheral blood stem-cell transplantation
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We evaluated the clinical impacts of the concurrent modification of post-transplant cyclophosphamide (PTCy) dose and tacrolimus (Tac)-initiation timing in 61 patients with human leukocyte antigen-haploidentical transplantation. Reduced-dose PTCy (80 mg/kg) was associated with a higher incidence of moderate-to-severe chronic graft-versus-host disease (GVHD) than standard-dose PTCy (100 mg/kg) (35.0% vs. 26.6%, p = 0.053). Notably, early-initiation Tac (day -1) increased moderate-to-severe chronic GVHD than standard-initiation Tac (day 5) in the reduced-dose PTCy group (p = 0.032), whereas Tac-initiation timing did not impact chronic GVHD in the standard-dose PTCy group. These data indicate that the combination of reduced-dose PTCy and early-initiation Tac can amplify chronic GVHD.
en-copyright=
kn-copyright=

en-aut-name=TeraoToshiki
en-aut-sei=Terao
en-aut-mei=Toshiki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=KondoTakumi
en-aut-sei=Kondo
en-aut-mei=Takumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=NakamuraMakoto
en-aut-sei=Nakamura
en-aut-mei=Makoto
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=TakasukaHiroki
en-aut-sei=Takasuka
en-aut-mei=Hiroki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=FujiwaraHideaki
en-aut-sei=Fujiwara
en-aut-mei=Hideaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=AsadaNoboru
en-aut-sei=Asada
en-aut-mei=Noboru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=EnnishiDaisuke
en-aut-sei=Ennishi
en-aut-mei=Daisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=NishimoriHisakazu
en-aut-sei=Nishimori
en-aut-mei=Hisakazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=FujiiKeiko
en-aut-sei=Fujii
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=MatsuokaKen-Ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-Ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

affil-num=1
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=2
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=3
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=4
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=5
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=6
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=7
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=8
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=9
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=10
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=11
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=12
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=
en-keyword=chronic GVHD
kn-keyword=chronic GVHD
en-keyword=haploidentical
kn-keyword=haploidentical
en-keyword=hematopoietic stem-cell transplantation
kn-keyword=hematopoietic stem-cell transplantation
en-keyword=PTCy
kn-keyword=PTCy
en-keyword=tacrolimus
kn-keyword=tacrolimus
END

start-ver=1.4
cd-journal=joma
no-vol=24
cd-vols=
no-issue=1
article-no=
start-page=140
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=20240422
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Endoscopic manifestation of intestinal transplant-associated microangiopathy after stem cell transplantation
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Background Endoscopic features of intestinal transplant-associated microangiopathy (iTAM) have not been comprehensively investigated. This study aimed to examine the endoscopic characteristics of patients diagnosed with iTAM.<br>
Methods This retrospective analysis included 14 patients pathologically diagnosed with iTAM after stem cell transplantation for hematolymphoid neoplasms (n = 13) or thalassemia (n = 1). The sex, age at diagnosis, endoscopic features, and prognosis of each patient were assessed. Serological markers for diagnosing transplant-associated thrombotic microangiopathy were also evaluated.<br>
Results The mean age at the time of iTAM diagnosis was 40.2 years. Patients diagnosed based on the pathognomonic pathological changes of iTAM presented with diverse symptoms at the times of endoscopic examinations, including diarrhea (n = 10), abdominal pain (n = 5), nausea (n = 4), appetite loss (n = 2), bloody stools (n = 2), abdominal discomfort (n = 1), and vomiting (n = 1). At the final follow-up, six patients survived, while eight patients succumbed, with a median time of 100.5 days (range: 52-247) post-diagnosis. Endoscopic manifestations included erythematous mucosa (n = 14), erosions (n = 13), ulcers (n = 9), mucosal edema (n = 9), granular mucosa (n = 9), and villous atrophy (n = 4). Erosions and/or ulcers were primarily observed in the colon (10/14, 71%), followed by the ileum (9/13, 69%), stomach (4/10, 40%), cecum (5/14, 36%), duodenum (3/10, 30%), rectum (4/14, 29%), and esophagus (1/10, 10%). Cytomegalovirus infection (n = 4) and graft-versus-host disease (n = 2) coexisted within the gastrointestinal tract. Patients had de novo prolonged or progressive thrombocytopenia (6/14, 43%), decreased hemoglobin concentration (4/14, 29%), reduced serum haptoglobin level (3/14, 21%), and a sudden and persistent increase in lactate dehydrogenase level (2/14, 14%). Peripheral blood samples from 12 patients were evaluated for schistocytes, with none exceeding 4%.<br>
Conclusions This study provides a comprehensive exploration of the endoscopic characteristics of iTAM. Notably, all patients exhibited erythematous mucosa throughout the gastrointestinal tract, accompanied by prevalent manifestations, such as erosions (93%), ulcers (64%), mucosal edema (64%), granular mucosa (64%), and villous atrophy (29%). Because of the low positivity for serological markers of transplant-associated thrombotic microangiopathy in patients with iTAM, endoscopic evaluation and biopsy of these lesions are crucial, even in the absence of these serological features.
en-copyright=
kn-copyright=

en-aut-name=IwamuroMasaya
en-aut-sei=Iwamuro
en-aut-mei=Masaya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=EnnishiDaisuke
en-aut-sei=Ennishi
en-aut-mei=Daisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=MatsuokaKen-Ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-Ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=TanakaTakehiro
en-aut-sei=Tanaka
en-aut-mei=Takehiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=InokuchiToshihiro
en-aut-sei=Inokuchi
en-aut-mei=Toshihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=HiraokaSakiko
en-aut-sei=Hiraoka
en-aut-mei=Sakiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=OtsukaMotoyuki
en-aut-sei=Otsuka
en-aut-mei=Motoyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

affil-num=1
en-affil=Department of Gastroenterology and Hepatology, Okayama University  Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=2
en-affil=Department of Hematology and Oncology, Okayama University  Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=3
en-affil=Department of Hematology and Oncology, Okayama University  Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=4
en-affil=Department of Hematology and Oncology, Okayama University  Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=5
en-affil=Department of Pathology, Okayama University Graduate School of  Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=6
en-affil=Department of Gastroenterology and Hepatology, Okayama University  Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=7
en-affil=Department of Gastroenterology and Hepatology, Okayama University  Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=8
en-affil=Department of Gastroenterology and Hepatology, Okayama University  Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=
en-keyword=Colonoscopy
kn-keyword=Colonoscopy
en-keyword=Esophagogastroduodenoscopy
kn-keyword=Esophagogastroduodenoscopy
en-keyword=Graft-versus-host disease
kn-keyword=Graft-versus-host disease
en-keyword=Hematopoietic stem cell transplantation
kn-keyword=Hematopoietic stem cell transplantation
en-keyword=Intestinal transplant-associated microangiopathy
kn-keyword=Intestinal transplant-associated microangiopathy
en-keyword=iTAM
kn-keyword=iTAM
END

start-ver=1.4
cd-journal=joma
no-vol=78
cd-vols=
no-issue=2
article-no=
start-page=123
end-page=134
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=202404
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Sigle Agent of Posttransplant Cyclophosphamide Without Calcineurin Inhibitor Controls Severity of Experimental Chronic GVHD
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Chronic graft-versus-host disease (GVHD) is a major cause of late death and morbidity following allogeneic hematopoietic cell transplantation (HCT), but its pathogenesis remains unclear. Recently, haplo-identical HCT with post-transplant cyclophosphamide (Haplo-HCT with PTCY) was found to achieve a low incidence rate of acute GVHD and chronic GVHD. However, while the pathogenesis of acute GVHD following Haplo-HCT with PTCY has been well investigated, that of chronic GVHD remains to be elucidated, especially in HLA-matched HCT with PTCY. Based on its safety profile, PTCY is currently applied for the human leucocyte antigen (HLA)-matched HCT setting. Here, we investigated the mechanisms of chronic GVHD following HLA-matched HCT with PTCY using a well-defined mouse chronic GVHD model. PTCY attenuated clinical and pathological chronic GVHD by suppressing effector T-cells and preserving regulatory T-cells compared with a control group. Additionally, we demonstrated that cyclosporine A (CsA) did not show any additional positive effects on attenuation of GVHD in PTCY-treated recipients. These results suggest that monotherapy with PTCY without CsA could be a promising strategy for the prevention of chronic GVHD following HLA-matched HCT.
en-copyright=
kn-copyright=

en-aut-name=SaekiKyosuke
en-aut-sei=Saeki
en-aut-mei=Kyosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=FujiwaraHideaki
en-aut-sei=Fujiwara
en-aut-mei=Hideaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=SeikeKeisuke
en-aut-sei=Seike
en-aut-mei=Keisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=KuroiTaiga
en-aut-sei=Kuroi
en-aut-mei=Taiga
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=NishimoriHisakazu
en-aut-sei=Nishimori
en-aut-mei=Hisakazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=TanakaTakehiro
en-aut-sei=Tanaka
en-aut-mei=Takehiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=MatsuokaKen-ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

affil-num=1
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=2
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=3
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=4
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=5
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=6
en-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=7
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=8
en-affil=Division of Transfusion, Okayama University Hospital
kn-affil=

affil-num=9
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
en-keyword=GVHD
kn-keyword=GVHD
en-keyword=posttransplant cyclophosphamide
kn-keyword=posttransplant cyclophosphamide
en-keyword=hematopoietic cell transplantation
kn-keyword=hematopoietic cell transplantation
en-keyword=HLA-identical
kn-keyword=HLA-identical
END

start-ver=1.4
cd-journal=joma
no-vol=4
cd-vols=
no-issue=
article-no=
start-page=31
end-page=39
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=20240331
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Advanced Hospital Training Activities in Fiscal 2023
kn-title=2023年度における「先進病院実習」の取り組み
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=MORITAMizuki
en-aut-sei=MORITA
en-aut-mei=Mizuki
kn-aut-name=森田瑞樹
kn-aut-sei=森田
kn-aut-mei=瑞樹
aut-affil-num=1
ORCID=

en-aut-name=MORITomoaki
en-aut-sei=MORI
en-aut-mei=Tomoaki
kn-aut-name=森友明
kn-aut-sei=森
kn-aut-mei=友明
aut-affil-num=2
ORCID=

en-aut-name=AIDAToshiaki
en-aut-sei=AIDA
en-aut-mei=Toshiaki
kn-aut-name=相田敏明
kn-aut-sei=相田
kn-aut-mei=敏明
aut-affil-num=3
ORCID=

en-aut-name=WATANABEToyohiko
en-aut-sei=WATANABE
en-aut-mei=Toyohiko
kn-aut-name=渡邉豊彦
kn-aut-sei=渡邉
kn-aut-mei=豊彦
aut-affil-num=4
ORCID=

en-aut-name=FUJIIDaiji
en-aut-sei=FUJII
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=5
ORCID=

en-aut-name=HARADANahoko
en-aut-sei=HARADA
en-aut-mei=Nahoko
kn-aut-name=原田奈穂子
kn-aut-sei=原田
kn-aut-mei=奈穂子
aut-affil-num=6
ORCID=

en-aut-name=HAKAMADARei
en-aut-sei=HAKAMADA
en-aut-mei=Rei
kn-aut-name=袴田玲
kn-aut-sei=袴田
kn-aut-mei=玲
aut-affil-num=7
ORCID=

en-aut-name=YOSHIBAYasuyuki
en-aut-sei=YOSHIBA
en-aut-mei=Yasuyuki
kn-aut-name=吉葉恭行
kn-aut-sei=吉葉
kn-aut-mei=恭行
aut-affil-num=8
ORCID=

affil-num=1
en-affil=Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学学術研究院ヘルスシステム統合科学学域

affil-num=2
en-affil=Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学学術研究院ヘルスシステム統合科学学域

affil-num=3
en-affil=Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学学術研究院ヘルスシステム統合科学学域

affil-num=4
en-affil=Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学学術研究院ヘルスシステム統合科学学域

affil-num=5
en-affil=Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学学術研究院ヘルスシステム統合科学学域

affil-num=6
en-affil=Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学学術研究院ヘルスシステム統合科学学域

affil-num=7
en-affil=Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学学術研究院ヘルスシステム統合科学学域

affil-num=8
en-affil=Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学学術研究院ヘルスシステム統合科学学域
END

start-ver=1.4
cd-journal=joma
no-vol=7
cd-vols=
no-issue=24
article-no=
start-page=7459
end-page=7470
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=20231214
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Distribution and clinical impact of molecular subtypes with dark zone signature of DLBCL in a Japanese real-world study
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The distribution and clinical impact of cell-of-origin (COO) subtypes of diffuse large B-cell lymphoma (DLBCL) outside Western countries remain unknown. Recent literature also suggests that there is an additional COO subtype associated with the germinal center dark zone (DZ) that warrants wider validation to generalize clinical relevance. Here, we assembled a cohort of Japanese patients with untreated DLBCL and determined the refined COO subtypes, which include the DZ signature (DZsig), using the NanoString DLBCL90 assay. To compare the distribution and clinical characteristics of the molecular subtypes, we used a data set from the cohort of British Columbia Cancer (BCC) (n = 804). Through the 1050 patient samples on which DLBCL90 assay was successfully performed in our cohort, 35%, 45%, and 6% of patients were identified to have germinal center B-cell?like (GCB) DLBCL, activated B-cell?like (ABC) DLBCL, and DZsig-positive (DZsigpos) DLBCL, respectively, with the highest prevalence of ABC-DLBCL, differing significantly from the BCC result (P < .001). GCB-DLBCL, ABC-DLBCL, and DZsigpos-DLBCL were associated with 2-year overall survival rates of 88%, 75%, and 66%, respectively (P < .0001), with patients with DZsigpos-DLBCL having the poorest prognosis. In contrast, GCB-DLBCL without DZsig showed excellent outcomes after rituximab-containing immunochemotherapy. DZsigpos-DLBCL was associated with the significant enrichment of tumors with CD10 expression, concurrent MYC/BCL2 expression, and depletion of microenvironmental components (all, P < .05). These results provide evidence of the distinct distribution of clinically relevant molecular subtypes in Japanese DLBCL and that refined COO, as measured by the DLBCL90 assay, is a robust prognostic biomarker that is consistent across geographical areas.
en-copyright=
kn-copyright=

en-aut-name=UrataTomohiro
en-aut-sei=Urata
en-aut-mei=Tomohiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=NaoiYusuke
en-aut-sei=Naoi
en-aut-mei=Yusuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=JiangAixiang
en-aut-sei=Jiang
en-aut-mei=Aixiang
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=BoyleMerrill
en-aut-sei=Boyle
en-aut-mei=Merrill
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=SunamiKazutaka
en-aut-sei=Sunami
en-aut-mei=Kazutaka
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=ImaiToshi
en-aut-sei=Imai
en-aut-mei=Toshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=NawaYuichiro
en-aut-sei=Nawa
en-aut-mei=Yuichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=HiramatsuYasushi
en-aut-sei=Hiramatsu
en-aut-mei=Yasushi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=YamamotoKazuhiko
en-aut-sei=Yamamoto
en-aut-mei=Kazuhiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=FujiiSoichiro
en-aut-sei=Fujii
en-aut-mei=Soichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=YoshidaIsao
en-aut-sei=Yoshida
en-aut-mei=Isao
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=YanoTomofumi
en-aut-sei=Yano
en-aut-mei=Tomofumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=ChijimatsuRyota
en-aut-sei=Chijimatsu
en-aut-mei=Ryota
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

en-aut-name=MurakamiHiroyuki
en-aut-sei=Murakami
en-aut-mei=Hiroyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=

en-aut-name=IkeuchiKazuhiro
en-aut-sei=Ikeuchi
en-aut-mei=Kazuhiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=

en-aut-name=KobayashiHiroki
en-aut-sei=Kobayashi
en-aut-mei=Hiroki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=16
ORCID=

en-aut-name=TaniKatsuma
en-aut-sei=Tani
en-aut-mei=Katsuma
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=17
ORCID=

en-aut-name=UjiieHideki
en-aut-sei=Ujiie
en-aut-mei=Hideki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=18
ORCID=

en-aut-name=InoueHirofumi
en-aut-sei=Inoue
en-aut-mei=Hirofumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=19
ORCID=

en-aut-name=TomidaShuta
en-aut-sei=Tomida
en-aut-mei=Shuta
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=20
ORCID=

en-aut-name=YamamotoAkira
en-aut-sei=Yamamoto
en-aut-mei=Akira
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=21
ORCID=

en-aut-name=KondoTakumi
en-aut-sei=Kondo
en-aut-mei=Takumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=22
ORCID=

en-aut-name=FujiwaraHideaki
en-aut-sei=Fujiwara
en-aut-mei=Hideaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=23
ORCID=

en-aut-name=AsadaNoboru
en-aut-sei=Asada
en-aut-mei=Noboru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=24
ORCID=

en-aut-name=NishimoriHisakazu
en-aut-sei=Nishimori
en-aut-mei=Hisakazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=25
ORCID=

en-aut-name=FujiiKeiko
en-aut-sei=Fujii
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=26
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=27
ORCID=

en-aut-name=MatsuokaKen-ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=28
ORCID=

en-aut-name=SawadaKeisuke
en-aut-sei=Sawada
en-aut-mei=Keisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=29
ORCID=

en-aut-name=MomoseShuji
en-aut-sei=Momose
en-aut-mei=Shuji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=30
ORCID=

en-aut-name=TamaruJun-ichi
en-aut-sei=Tamaru
en-aut-mei=Jun-ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=31
ORCID=

en-aut-name=NishikoriAsami
en-aut-sei=Nishikori
en-aut-mei=Asami
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=32
ORCID=

en-aut-name=SatoYasuharu
en-aut-sei=Sato
en-aut-mei=Yasuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=33
ORCID=

en-aut-name=YoshinoTadashi
en-aut-sei=Yoshino
en-aut-mei=Tadashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=34
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=35
ORCID=

en-aut-name=ScottDavid W.
en-aut-sei=Scott
en-aut-mei=David W.
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=36
ORCID=

en-aut-name=EnnishiDaisuke
en-aut-sei=Ennishi
en-aut-mei=Daisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=37
ORCID=

affil-num=1
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=2
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=3
en-affil=British Columbia Cancer, Centre for Lymphoid Cancer
kn-affil=

affil-num=4
en-affil=British Columbia Cancer, Centre for Lymphoid Cancer
kn-affil=

affil-num=5
en-affil=Department of Hematology, NHO Okayama Medical Center
kn-affil=

affil-num=6
en-affil=Department of Hematology and Blood Transfusion, Kochi Health Sciences Center
kn-affil=

affil-num=7
en-affil=Division of Hematology, Ehime Prefectural Central Hospital
kn-affil=

affil-num=8
en-affil=Department of Hematology and Oncology, Japanese Red Cross Society Himeji Hospital
kn-affil=

affil-num=9
en-affil=Department of Hematology and Oncology, Okayama City Hospital
kn-affil=

affil-num=10
en-affil=Department of Hematology, Japanese Red Cross Okayama Hospital
kn-affil=

affil-num=11
en-affil=Department of Hematologic Oncology, NHO Shikoku Cancer Center
kn-affil=

affil-num=12
en-affil=Department of Internal Medicine, Okayama Rosai Hospital
kn-affil=

affil-num=13
en-affil=Center for Comprehensive Genomic Medicine, Okayama University Hospital
kn-affil=

affil-num=14
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=15
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=16
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=17
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=18
en-affil=Center for Comprehensive Genomic Medicine, Okayama University Hospital
kn-affil=

affil-num=19
en-affil=Clinical Genomic Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Science
kn-affil=

affil-num=20
en-affil=Center for Comprehensive Genomic Medicine, Okayama University Hospital
kn-affil=

affil-num=21
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=22
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=23
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=24
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=25
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=26
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=27
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=28
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=29
en-affil=Department of Pathology, Saitama Medical Center, Saitama Medical University
kn-affil=

affil-num=30
en-affil=Department of Pathology, Saitama Medical Center, Saitama Medical University
kn-affil=

affil-num=31
en-affil=Department of Pathology, Saitama Medical Center, Saitama Medical University
kn-affil=

affil-num=32
en-affil=Department of Molecular Hematopathology, Okayama University Graduate School of Health Sciences
kn-affil=

affil-num=33
en-affil=Department of Molecular Hematopathology, Okayama University Graduate School of Health Sciences
kn-affil=

affil-num=34
en-affil=Department of Pathology, Okayama University
kn-affil=

affil-num=35
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=36
en-affil=British Columbia Cancer, Centre for Lymphoid Cancer
kn-affil=

affil-num=37
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=20230925
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=生体肺移植後の長期的なドナーQOLの検討
kn-title=Donor’s long-term quality of life following living-donor lobar lung transplantation
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FUJIIKento
en-aut-sei=FUJII
en-aut-mei=Kento
kn-aut-name=藤井健人
kn-aut-sei=藤井
kn-aut-mei=健人
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=55
cd-vols=
no-issue=2
article-no=
start-page=1
end-page=14
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=20231124
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Building a perspective on the innovation process of local public services
kn-title=地方公共サービス革新プロセスの視座の構築
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=　When local governments develop public services, they often experience innovation processes. More often, the innovation processes referred to here seem to be the perceived needs for transformation faced with external pressures and the purposive responses to them. This article tries to depict this discourse from a different viewpoint. One of the perspectives that has been proposed so far is that the external environments are made up of multiple actors, and that the historical backgrounds and the relationships between these actors affect the structure of administrative organizations and the methods of providing public services. The transformation processes could be one-time events no matter how long the processes may take, but this article tries to argue they may connote a circular mechanism where both of the administrative organizations and the external actors feedback to each other. In order to elaborate this direction of theorizing, three steps are employed by applying existent literature of various types developed in rather a broader context of social sciences. First, if one of the goals of postmodern theorization is liberating the psychological energies of actors from the cramped social reality that structuralists postulated, then Actor-Network-Theory may be useful. Second, according to Sarasbathy’s research on entrepreneurial behaviors, the view that we effectuate our future through what we can do now is attractive in order to create a new discourse of social innovations, where we appreciate them as not springing out of nowhere all of sudden. Third, once this article accepts polyphonic views on social realities where congested discourses interact during abovementioned process, the role of civic entrepreneurs on the frontline can never be overstated enough. This is because such civic entrepreneurs could cooperate with minority opinions and raise them into broader contexts of dialogues within societies.
en-copyright=
kn-copyright=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=1
ORCID=

en-aut-name=KanajiHiroshi
en-aut-sei=Kanaji
en-aut-mei=Hiroshi
kn-aut-name=金治宏
kn-aut-sei=金治
kn-aut-mei=宏
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学学術研究院ヘルスシステム統合科学学域

affil-num=2
en-affil=
kn-affil=京都光華女子大学キャリア形成学部
en-keyword=local government
kn-keyword=local government
en-keyword=public services
kn-keyword=public services
en-keyword=innovation process
kn-keyword=innovation process
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=20050930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=金属酸化物複合型ヒドロキシアパタイトの創成と生理活物質の特異吸着現象
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井英司
kn-aut-sei=藤井
kn-aut-mei=英司
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=77
cd-vols=
no-issue=4
article-no=
start-page=347
end-page=357
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=202308
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Feasibility of Flow Cytometry Analysis of Gastrointestinal Tract-Residing Lymphocytes in Hematopoietic Stem Cell Transplant Recipients
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The feasibility of lymphocyte isolation and flow cytometry using a single endoscopic biopsy specimen from the gastrointestinal tract of patients who have undergone hematopoietic stem cell transplantation has not been investigated. We acquired 51 endoscopic biopsy specimens from the gastrointestinal tract of 35 patients. We divided the flow cytometry samples into two groups: group A, successful lymphocyte isolation (n=24), and group B, incomplete isolation (n=27). We compared the backgrounds of the samples between the groups to reveal crucial elements in the successful isolation of lymphocytes residing in the gastrointestinal tract. Comparison between the groups revealed lymphocyte isolation success rates differed between biopsy sites. Isolation was most successful in samples from the duodenum (8/9, 88.9%), followed by the ileum (4/8, 50.0%), large intestine (4/11, 36.4%), and stomach (8/23, 34.8%). Tacrolimus was used more frequently in group B (92.6%) than in group A (62.5%) (p=0.015). Logistic regression analysis revealed that isolation from the duodenum or ileum was a significant factor for successful isolation, while tacrolimus use was not statistically significant. In conclusion, the duodenum and ileum are more suitable sites than the stomach and colorectum for acquiring samples for flow cytometry.
en-copyright=
kn-copyright=

en-aut-name=IwamuroMasaya
en-aut-sei=Iwamuro
en-aut-mei=Masaya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=KondoTakumi
en-aut-sei=Kondo
en-aut-mei=Takumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=EnnishiDaisuke
en-aut-sei=Ennishi
en-aut-mei=Daisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=MatsuokaKen-ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=TakahashiTakahide
en-aut-sei=Takahashi
en-aut-mei=Takahide
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=HirabataAraki
en-aut-sei=Hirabata
en-aut-mei=Araki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=TanakaTakehiro
en-aut-sei=Tanaka
en-aut-mei=Takehiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=OtsukaFumio
en-aut-sei=Otsuka
en-aut-mei=Fumio
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=OkadaHiroyuki
en-aut-sei=Okada
en-aut-mei=Hiroyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

affil-num=1
en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=2
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=3
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=4
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=5
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=6
en-affil=Division of Medical Support, Okayama University Hospital
kn-affil=

affil-num=7
en-affil=Division of Medical Support, Okayama University Hospital
kn-affil=

affil-num=8
en-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=9
en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=10
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=11
en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
en-keyword=flow cytometry
kn-keyword=flow cytometry
en-keyword=stem cell transplantation
kn-keyword=stem cell transplantation
en-keyword=transplantation-associated microangiopathy
kn-keyword=transplantation-associated microangiopathy
END

start-ver=1.4
cd-journal=joma
no-vol=55
cd-vols=
no-issue=1
article-no=
start-page=77
end-page=87
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=20230724
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Oda, N. “Dentou igaku” ga tsukurareru toki: Betonamu iryou seisaku shi［When “Science of Traditional Medicine” Was Constructed: A History of Medical Policy in Vietnam］（Kyoto University Press, 2022）
kn-title=小田なら著『〈伝統医学〉が創られるとき：ベトナム医療政策史』（京都大学学術出版会，2022年）
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=KinoshitaHiroshi
en-aut-sei=Kinoshita
en-aut-mei=Hiroshi
kn-aut-name=木下広志
kn-aut-sei=木下
kn-aut-mei=広志
aut-affil-num=1
ORCID=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=寿晃整骨院

affil-num=2
en-affil=
kn-affil=岡山大学学術研究院ヘルスシステム統合科学学域
END

start-ver=1.4
cd-journal=joma
no-vol=11
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=20230705
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Bilateral Lacrimal Gland Mantle Cell Lymphoma in 11-Year Follow-Up: Case Report and Review of 48 Cases With Ocular Adnexal Presentation in the Literature
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 63-year-old woman, with 11-year history of breast cancer, showed bilateral lacrimal gland enlargement on magnetic resonance imaging. Gallium-67 scintigraphy, as the standard at that time in 2004, demonstrated abnormally high uptake only in bilateral lacrimal glands. The lacrimal glands were extirpated and the pathological diagnosis was mantle cell lymphoma (MCL). She underwent bilateral orbital radiation, based on no uptake of gallium-67 in other sites of the body. In a month, bone marrow biopsy revealed the infiltration with MCL, positive for cyclin D1. She showed hepatic lymphadenopathy and splenomegaly, and so received 2 cycles of alternating Hyper-CVAD therapy and high-dose methotrexate with cytarabine, combined with rituximab, in 2 months, leading to complete remission. She underwent autologous peripheral blood stem cell transplantation and was well until the age of 68 years when she showed a recurrent intratracheal submucosal lesion of lymphoma and underwent one course of reduced-dose CHOP combined with rituximab. Next year, the left rib resection revealed the metastasis of breast adenocarcinoma, leading to daily oral letrozole. Further 2 years later, computed tomographic scan demonstrated multiple submucosal nodular lesions in the trachea and bronchi, together with cervical and supraclavicular lymphadenopathy, and intratracheal lesion biopsy and bone marrow biopsy proved the involvement with MCL. She underwent 2 courses of bendamustine and rituximab, resulting in complete remission but died of metastatic breast cancer at the age of 74 years. Clinical features in 48 previous cases with ocular adnexal MCL in the literature were summarized in this study.
en-copyright=
kn-copyright=

en-aut-name=MatsuoToshihiko
en-aut-sei=Matsuo
en-aut-mei=Toshihiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=TanakaTakehiro
en-aut-sei=Tanaka
en-aut-mei=Takehiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=OkadaKazuya
en-aut-sei=Okada
en-aut-mei=Kazuya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=NotoharaKenji
en-aut-sei=Notohara
en-aut-mei=Kenji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=FujiiKeiko
en-aut-sei=Fujii
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

affil-num=1
en-affil=Okayama University
kn-affil=

affil-num=2
en-affil=Okayama University
kn-affil=

affil-num=3
en-affil=Kurashiki Central Hospital
kn-affil=

affil-num=4
en-affil=Kurashiki Central Hospital
kn-affil=

affil-num=5
en-affil=Okayama University Hospital
kn-affil=

affil-num=6
en-affil=Okayama University Hospital
kn-affil=
en-keyword=mantle cell lymphoma
kn-keyword=mantle cell lymphoma
en-keyword=lacrimal gland
kn-keyword=lacrimal gland
en-keyword=autologous peripheral blood stem cell transplantation
kn-keyword=autologous peripheral blood stem cell transplantation
en-keyword=breast cancer
kn-keyword=breast cancer
en-keyword=tracheal and bronchial infiltration
kn-keyword=tracheal and bronchial infiltration
END

start-ver=1.4
cd-journal=joma
no-vol=63
cd-vols=
no-issue=7
article-no=
start-page=1344
end-page=1353
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=20230609
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Efficient granulocyte collection method using high concentrations of medium molecular weight hydroxyethyl starch
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Background: Granulocyte transfusion therapy is a rational therapeutic option for patients with prolonged, severe neutropenia. Although high molecular weight hydroxyethyl starch (hHES) facilitates the separation of red blood cells during granulocyte collection, renal dysfunction has been noted as a potential side effect. HES130/0.4 (Voluven?) is a medium molecular weight HES (mHES) with superior safety profiles compared to hHES. Although HES130/0.4 is reportedly effective in the collection of granulocytes, we lack studies comparing the efficiency of granulocyte collection using HES130/0.4 and hHES.<br>
Study Design and Methods: We retrospectively collected the data from 60 consecutive apheresis procedures performed on 40 healthy donors at the Okayama University Hospital between July 2013 and December 2021. All procedures were performed using the Spectra Optia system. Based on the HES130/0.4 concentration in the separation chamber, granulocyte collection methods using HES130/0.4 were classified into m0.46, m0.44, m0.37, and m0.8 groups. We used HES130/0.4 and hHES groups to compare the various sample collection methods.<br>
Results: The median granulocyte collection efficiency (CE) was approximately 24.0% and 28.1% in the m0.8 and hHES groups, respectively, which were significantly higher than those in the m0.46, m0.44, and m0.37 groups. One month following granulocyte collection with HES130/0.4, no significant changes were observed in serum creatinine levels compared to those before the donation.<br>
Conclusion: Therefore, we propose a granulocyte collection approach employing HES130/0.4, which is comparable to the use of hHES in terms of the granulocyte CE. A high concentration of HES130/0.4 in the separation chamber was considered crucial for granulocyte collection.
en-copyright=
kn-copyright=

en-aut-name=KondoTakumi
en-aut-sei=Kondo
en-aut-mei=Takumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=FujiiKeiko
en-aut-sei=Fujii
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=SumiiYuichi
en-aut-sei=Sumii
en-aut-mei=Yuichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=UrataTomohiro
en-aut-sei=Urata
en-aut-mei=Tomohiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=KimuraMaiko
en-aut-sei=Kimura
en-aut-mei=Maiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=MatsudaMasayuki
en-aut-sei=Matsuda
en-aut-mei=Masayuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=IkegawaShuntaro
en-aut-sei=Ikegawa
en-aut-mei=Shuntaro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=WashioKana
en-aut-sei=Washio
en-aut-mei=Kana
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=FujiwaraHideaki
en-aut-sei=Fujiwara
en-aut-mei=Hideaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=AsadaNoboru
en-aut-sei=Asada
en-aut-mei=Noboru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=EnnishiDaisuke
en-aut-sei=Ennishi
en-aut-mei=Daisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=NishimoriHisakazu
en-aut-sei=Nishimori
en-aut-mei=Hisakazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

en-aut-name=MatsuokaKen‐ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken‐ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=

en-aut-name=OtsukaFumio
en-aut-sei=Otsuka
en-aut-mei=Fumio
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=16
ORCID=

affil-num=1
en-affil=Division of Transfusion, Okayama University Hospital
kn-affil=

affil-num=2
en-affil=Division of Clinical Laboratory, Okayama University Hospital
kn-affil=

affil-num=3
en-affil=Division of Transfusion, Okayama University Hospital
kn-affil=

affil-num=4
en-affil=Division of Transfusion, Okayama University Hospital
kn-affil=

affil-num=5
en-affil=Division of Transfusion, Okayama University Hospital
kn-affil=

affil-num=6
en-affil=Division of Transfusion, Okayama University Hospital
kn-affil=

affil-num=7
en-affil=Division of Transfusion, Okayama University Hospital
kn-affil=

affil-num=8
en-affil=Division of Transfusion, Okayama University Hospital
kn-affil=

affil-num=9
en-affil=Department of Pediatrics/Pediatric Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=10
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=11
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=12
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=13
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=14
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=15
en-affil=Division of Clinical Laboratory, Okayama University Hospital
kn-affil=

affil-num=16
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=
en-keyword=blood center operations
kn-keyword=blood center operations
en-keyword=cellular therapy
kn-keyword=cellular therapy
en-keyword=therapeutic apheresis
kn-keyword=therapeutic apheresis
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=20230324
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=実践的なセキュリティオペレーションの高度化と効率化に関する研究
kn-title=Research on Sophistication and Improving Efficiency of Practical Security Operations
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FUJIIShota
en-aut-sei=FUJII
en-aut-mei=Shota
kn-aut-name=藤井翔太
kn-aut-sei=藤井
kn-aut-mei=翔太
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Natural Science and Technology, Okayama university
kn-affil=岡山大学大学院自然科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=13
cd-vols=
no-issue=
article-no=
start-page=69
end-page=82
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=20230330
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Implementing a Professional Learning Community (PLC) at Early Childhood Education Institutions Focus on the Process of Curriculum Management
kn-title=幼稚園・保育所・幼保連携型認定こども園における｢専門職の学習共同体｣の醸成 ―教育・保育課程等編成のプロセスに着目して―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=　本研究では，幼稚園・保育所・幼保連携型認定こども園においてP L C 醸成をめざした際の，教育・保育課程等編成のプロセスを明らかにすることを目的とした。カリキュラム・マネジメントによる学校文化変革のプロセスとP T L C の関係性を整理した上で，PLC 醸成をめざしたカリキュラム編成のプロセスを示し，それをもとに， P L C 醸成にむけた教育・保育課程等編成のプロセスを示した。そして，『幼稚園教育要領解説』，『保育所保育指針解説』，『幼保連携型認定こども園教育・保育要領解説』で示された教育・保育課程等編成の手順と比較し，プロセスやリーダーシップのあり方に関する違いが確認できた。
en-copyright=
kn-copyright=

en-aut-name=FujiiYushi
en-aut-sei=Fujii
en-aut-mei=Yushi
kn-aut-name=藤井裕士
kn-aut-sei=藤井
kn-aut-mei=裕士
aut-affil-num=1
ORCID=

en-aut-name=KumagaiShinnosuke
en-aut-sei=Kumagai
en-aut-mei=Shinnosuke
kn-aut-name=熊谷愼之輔
kn-aut-sei=熊谷
kn-aut-mei=愼之輔
aut-affil-num=2
ORCID=

affil-num=1
en-affil=Kurashiki Municipal Kurashiki Special Needs School
kn-affil=倉敷市立倉敷支援学校

affil-num=2
en-affil=Faculty of Education, Okayama University
kn-affil=岡山大学学術研究院教育学域
en-keyword=専門職の学習共同体(Professional Learning Community)
kn-keyword=専門職の学習共同体(Professional Learning Community)
en-keyword=専門性(Expertise)
kn-keyword=専門性(Expertise)
en-keyword=教育・保育課程の編成 (Curriculum Management)
kn-keyword=教育・保育課程の編成 (Curriculum Management)
END

start-ver=1.4
cd-journal=joma
no-vol=127
cd-vols=
no-issue=5
article-no=
start-page=2223
end-page=2230
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=20230124
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Uniform Formation of a Characteristic Nanocomposite Structure of Biogenous Iron Oxide for High Rate Performance as the Anode of Lithium-Ion Batteries
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Recently, Fe2O3 has been considered as an alternative anode material for lithium-ion batteries (LIBs) owing to its high theoretical capacity (approximately 1000 mA h g-1), low cost, and nontoxicity. However, its rate performance remains poor relative to that of the conventional graphite anode. In this study, Fe2O3-based anodes were prepared through the annealing of biogenous Fe2O3 (L-BIOX) samples produced by an aquatic Fe-oxidizing bacterium. The effect of the annealing temperature on the performance of the synthesized Fe2O3-based material as the anode of an LIB was investigated. Electrochemical measurements revealed that the annealed L-BIOX samples at 300-700 degrees C exhibited higher rate performances than the unannealed material. Particularly, the sample annealed at 700 degrees C exhibited the highest capacity among the synthesized materials and showed a higher performance than the previously reported Fe2O3-based anodes. It exhibited a capacity of 923 mA h g-1 even at a high current density of 2 A g-1. After annealing at 700 degrees C and discharging, the synthesized biogenous material had a uniform nanocomposite structure composed of alpha-Fe2O3 nanoparticles dispersed in an amorphous matrix of Li-Si-P oxide. To form this uniform nanostructure, the solid-state diffusion resistance of the Li+ ions in the active material was reduced, which consequently improved the rate performance of the electrode. Therefore, this study provides substantial insights into the development and improvement of the performance of novel Fe2O3-based nanomaterials as the anode of LIBs.
en-copyright=
kn-copyright=

en-aut-name=TakahashiMasakuni
en-aut-sei=Takahashi
en-aut-mei=Masakuni
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=SakumaRyo
en-aut-sei=Sakuma
en-aut-mei=Ryo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=HashimotoHideki
en-aut-sei=Hashimoto
en-aut-mei=Hideki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=FujiiTatsuo
en-aut-sei=Fujii
en-aut-mei=Tatsuo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=TakadaJun
en-aut-sei=Takada
en-aut-mei=Jun
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

affil-num=1
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=2
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=3
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=4
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=5
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=15
cd-vols=
no-issue=3
article-no=
start-page=974
end-page=979
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=20221108
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Sequential Combination of FLAM and Venetoclax plus Azacitidine to Bridge to Cord Blood Transplantation in a Patient with Primary Induction Failure Acute Myeloid Leukemia
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Venetoclax (VEN) is an oral B-cell lymphoma-2 (BCL-2) inhibitor that has been widely used to treat various hematological disorders. Recent studies have demonstrated that VEN in combination with fludarabine-enhanced high-dose cytarabine (FLA) is effective for treating relapsed or refractory acute myeloid leukemia (AML). In the combination therapy, salvage chemotherapy and VEN are basically concurrently administrated; however, further optimization may enable the treatment to apply to larger numbers of patients with various clinical backgrounds. Here, we describe a case of refractory AML treated with a sequential combination of the intensive chemotherapy (fludarabine, cytarabine, and mitoxantrone; FLAM) and VEN/AZA to bridge to an unrelated cord blood transplantation (uCBT). By continuously adding VEN/AZA after FLAM, the patient achieved morphologic leukemia free state with only minor toxicities. Blood cell counts did not recover until the time of transplantation because of the deep myelosuppression caused by the treatment sequence, but the infection risk was safely managed during this period. After engraftment, maintenance therapy with VEN/AZA was performed, and the patient has survived without disease recurrence for over 9 months after transplantation. Our case suggests that bridging therapy with VEN and AZA from the time of the last chemotherapy to allogeneic transplantation may provide an effective and tolerable treatment strategy for refractory AML. Further studies of larger numbers of cases are needed to validate the effectiveness of this treatment.
en-copyright=
kn-copyright=

en-aut-name=MurakamiHiroyuki
en-aut-sei=Murakami
en-aut-mei=Hiroyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=MatsuokaKen-Ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-Ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=AsanoTakeru
en-aut-sei=Asano
en-aut-mei=Takeru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=MoriyamaTakashi
en-aut-sei=Moriyama
en-aut-mei=Takashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=MatsumuraAkifumi
en-aut-sei=Matsumura
en-aut-mei=Akifumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=FujiwaraHideaki
en-aut-sei=Fujiwara
en-aut-mei=Hideaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=AsadaNoboru
en-aut-sei=Asada
en-aut-mei=Noboru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=EnnishiDaisuke
en-aut-sei=Ennishi
en-aut-mei=Daisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=NishimoriHisakazu
en-aut-sei=Nishimori
en-aut-mei=Hisakazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=FujiiKeiko
en-aut-sei=Fujii
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=TojiTomohiro
en-aut-sei=Toji
en-aut-mei=Tomohiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=YoshinoTadashi
en-aut-sei=Yoshino
en-aut-mei=Tadashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=

affil-num=1
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=2
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=3
en-affil=Department of Hematology and Oncology, Japanese Red Cross Society Himeji Hospital
kn-affil=

affil-num=4
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=5
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=6
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=7
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=8
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=9
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=10
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=11
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=12
en-affil=Department of Pathology, Okayama University Hospital
kn-affil=

affil-num=13
en-affil=Department of Pathology, Okayama University Hospital
kn-affil=

affil-num=14
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=
en-keyword=Refractory acute myeloid leukemia
kn-keyword=Refractory acute myeloid leukemia
en-keyword=Transplant
kn-keyword=Transplant
en-keyword=B-cell lymphoma-2
kn-keyword=B-cell lymphoma-2
en-keyword=Azacitidine
kn-keyword=Azacitidine
en-keyword=Venetoclax
kn-keyword=Venetoclax
END

start-ver=1.4
cd-journal=joma
no-vol=41
cd-vols=
no-issue=
article-no=
start-page=9
end-page=13
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190401
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=モモ‘紅清水’における赤肉果の音響振動法による非破壊判別技術の検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FukudaFumio
en-aut-sei=Fukuda
en-aut-mei=Fumio
kn-aut-name=福田文夫
kn-aut-sei=福田
kn-aut-mei=文夫
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=近藤毅典
kn-aut-sei=近藤
kn-aut-mei=毅典
aut-affil-num=2
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井雄一郎
kn-aut-sei=藤井
kn-aut-mei=雄一郎
aut-affil-num=3
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=河井崇
kn-aut-sei=河井
kn-aut-mei=崇
aut-affil-num=4
ORCID=

en-aut-name=HiranoKen
en-aut-sei=Hirano
en-aut-mei=Ken
kn-aut-name=平野健
kn-aut-sei=平野
kn-aut-mei=健
aut-affil-num=5
ORCID=

en-aut-name=MorinagaKunihisa
en-aut-sei=Morinaga
en-aut-mei=Kunihisa
kn-aut-name=森永邦久
kn-aut-sei=森永
kn-aut-mei=邦久
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学農学部附属山陽圏フィールド科学センター

affil-num=2
en-affil=
kn-affil=岡山大学農学部附属山陽圏フィールド科学センター

affil-num=3
en-affil=
kn-affil=岡山県農林水産総合センター農業研究所

affil-num=4
en-affil=
kn-affil=岡山大学大学院環境生命科学研究科

affil-num=5
en-affil=
kn-affil=岡山大学大学院環境生命科学研究科

affil-num=6
en-affil=
kn-affil=岡山大学大学院環境生命科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=17
cd-vols=
no-issue=9
article-no=
start-page=e0273749
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=20220909
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Prevention of non-infectious pulmonary complications after intra-bone marrow stem cell transplantation in mice
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Non-infectious pulmonary complications including idiopathic pneumonia syndrome (IPS) and bronchiolitis obliterans syndrome (BOS), which are clinical and diagnostic manifestations of lung chronic graft-versus-host disease (GVHD), cause significant mortality after allogeneic stem cell transplantation (SCT). Increasing evidence suggests that alloantigen reactions in lung tissue play a central role in the pathogenesis of IPS and BOS; however, the mechanism is not fully understood. Several clinical and experimental studies have reported that intrabone marrow (IBM)-SCT provides high rates of engraftment and is associated with a low incidence of acute GVHD. In the present study, allogeneic SCT was conducted in mouse models of IPS and BOS, to compare intravenous (IV)-SCT with IBM-SCT. Allogeneic IBM-SCT improved the clinical and pathological outcomes of pulmonary complications compared to those of IV-SCT. The mechanisms underlying the reductions in pulmonary complications in IBM-SCT mice were explored. The infiltrating lung cells were mainly CD11b+ myeloid and CD3+ T cells, in the same proportions as in transplanted donor cells. In an in vivo bioluminescence imaging, a higher proportion of injected donor cells was detected in the lung during the early phase (1 h after IV-SCT) than after IBM-SCT (16.7 +/- 1.1 vs. 3.1 +/- 0.7 x 10(5) photons/s/animal, IV-SCT vs. IBM-SCT, P = 1.90 x 10(-10)). In the late phase (5 days) after SCT, there were also significantly more donor cells in the lung after IV-SCT than after IBM-SCT or allogeneic-SCT (508.5 +/- 66.1 vs. 160.1 +/- 61.9 x 10(6) photons/s/animal, IV-SCT vs. IBM-SCT, P = 0.001), suggesting that the allogeneic reaction induces sustained donor cell infiltration in the lung during the late phase. These results demonstrated that IBM-SCT is capable of reducing injected donor cells in the lung; IBM-SCT decreases donor cell infiltration. IBM-SCT therefore represents a promising transplantation strategy for reducing pulmonary complications, by suppressing the first step in the pathophysiology of chronic GVHD.
en-copyright=
kn-copyright=

en-aut-name=Yamasuji-MaedaYoshiko
en-aut-sei=Yamasuji-Maeda
en-aut-mei=Yoshiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=NishimoriHisakazu
en-aut-sei=Nishimori
en-aut-mei=Hisakazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=SeikeKeisuke
en-aut-sei=Seike
en-aut-mei=Keisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=YamamotoAkira
en-aut-sei=Yamamoto
en-aut-mei=Akira
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=FujiwaraHideaki
en-aut-sei=Fujiwara
en-aut-mei=Hideaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=KuroiTaiga
en-aut-sei=Kuroi
en-aut-mei=Taiga
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=SaekiKyosuke
en-aut-sei=Saeki
en-aut-mei=Kyosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=FujinagaHaruko
en-aut-sei=Fujinaga
en-aut-mei=Haruko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=OkamotoSachiyo
en-aut-sei=Okamoto
en-aut-mei=Sachiyo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=MatsuokaKen-Ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-Ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=TanakaTakehiro
en-aut-sei=Tanaka
en-aut-mei=Takehiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=FujiiMasahiro
en-aut-sei=Fujii
en-aut-mei=Masahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

en-aut-name=MominokiKatsumi
en-aut-sei=Mominoki
en-aut-mei=Katsumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=

en-aut-name=KanekuraTakuro
en-aut-sei=Kanekura
en-aut-mei=Takuro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=16
ORCID=

affil-num=1
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=2
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=3
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=4
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=5
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=6
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=7
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=8
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=9
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=10
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=11
en-affil=Department of Transfusion Medicine, Okayama University Hospital
kn-affil=

affil-num=12
en-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=13
en-affil=Department of Animal Resources, Advanced Science Research Center, Okayama University
kn-affil=

affil-num=14
en-affil=Department of Animal Resources, Advanced Science Research Center, Okayama University
kn-affil=

affil-num=15
en-affil=Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences
kn-affil=

affil-num=16
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=62
cd-vols=
no-issue=3
article-no=
start-page=187
end-page=189
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=2022
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=CD19 immunostaining of a stored paraffin-embedded vitrectomy cell block of intraocular lymphoma contributing to chimera antigen receptor T-cell therapy
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=MatsuoToshihiko
en-aut-sei=Matsuo
en-aut-mei=Toshihiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=TanakaTakehiro
en-aut-sei=Tanaka
en-aut-mei=Takehiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=FujiiKentaro
en-aut-sei=Fujii
en-aut-mei=Kentaro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=KondoEisei
en-aut-sei=Kondo
en-aut-mei=Eisei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

affil-num=1
en-affil=Regenerative and Reconstructive Medicine (Ophthalmology), Okayama University Graduate School of Interdisciplinary Science and Engineering in Health Systems
kn-affil=

affil-num=2
en-affil=Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=3
en-affil=Hematology/Oncology and Division of Blood Transfusion, Okayama University Hospital
kn-affil=

affil-num=4
en-affil=Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=5
en-affil=Hematology/Oncology, Kawasaki Medical School
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=7
cd-vols=
no-issue=15
article-no=
start-page=12795
end-page=12802
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=20220410
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Eco-Benign Orange-Hued Pigment Derived from Aluminum-Enriched Biogenous Iron Oxide Sheaths
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Inorganic pigments have been widely used due to their low cost of production, strong hiding power, and chemical resistance; nevertheless, they have limited hue width and chromaticity. To eliminate these disadvantages, we herein propose the use of an ingenious biotemplate technique to produce Al-enriched biogenic iron oxide (BIOX) materials. Spectrophotometric color analysis showed that high levels of Al inclusion on heat-treated BIOX samples produced heightened yellowish hues and lightness. The Al-enriched BIOX sheaths exhibited a stable tubular structure and excellent thermal stability of color tones after heating at high temperatures and repetitive heat treatments. Ultrastructural analysis and mechanical destruction experiments revealed that the highly chromatic orange-hue of these pigments are ascribed probably to an ingenious cylindrical nanocomposite architecture composed of putative Fe-included low crystalline Al oxide regions and hematite particles embedded therein. The present work therefore demonstrates that the bioengineered material can serve as an epochal orange-hued inorganic pigment with low toxicity and marked thermostability that should meet large industrial demand.
en-copyright=
kn-copyright=

en-aut-name=TamuraKatsunori
en-aut-sei=Tamura
en-aut-mei=Katsunori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=OshimaYuri
en-aut-sei=Oshima
en-aut-mei=Yuri
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=FuseYuta
en-aut-sei=Fuse
en-aut-mei=Yuta
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=NagaokaNoriyuki
en-aut-sei=Nagaoka
en-aut-mei=Noriyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=KunohTatsuki
en-aut-sei=Kunoh
en-aut-mei=Tatsuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=NakanishiMakoto
en-aut-sei=Nakanishi
en-aut-mei=Makoto
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=FujiiTatsuo
en-aut-sei=Fujii
en-aut-mei=Tatsuo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=NanbaTokuro
en-aut-sei=Nanba
en-aut-mei=Tokuro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=TakadaJun
en-aut-sei=Takada
en-aut-mei=Jun
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

affil-num=1
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=2
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=3
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=4
en-affil=Advanced Research Center for Oral and Craniofacial Sciences, Okayama University
kn-affil=

affil-num=5
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=6
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=7
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=8
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=9
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=3
article-no=
start-page=45
end-page=66
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=20220520
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The histry of railways in the Polish Kingdom in the nineteenth century? the case of Lodz region
kn-title=19世紀ポーランド王国における鉄道建設　−ウッジ繊維工業地帯を中心に−
en-subtitle=
kn-subtitle=
en-abstract=Railway development is a universal phenomenon in continental Europe of nineteenth century. On the one hand, railway construction was controled by government to a greater or lesser degree, but on the other hand the government helped build the railway. In any case, the development of railways was indispensable to industrialization of the country. In the middle of nineteenth century, when the railways were being build all over Europe, there was no independent Poland. The first railway built by Poles was the Warsaw ? Vienna Railway. It was a private initiative by Polish bankers, and it opened in 1845. The developing Lodz textile industry desired strongly to construct the railway to transport coal, raw materials and products in the city. But they had to wait for 20 years to get conection with railway. The efforts and actions of railway enterprizes and industrialists of the Polish Kingdom under domination by unfriendly Rusia were characteristic of the nineteenth century Poland.
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiKazuo
en-aut-sei=Fujii
en-aut-mei=Kazuo
kn-aut-name=藤井和夫
kn-aut-sei=藤井
kn-aut-mei=和夫
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=関西学院大学名誉教授
END

start-ver=1.4
cd-journal=joma
no-vol=2
cd-vols=
no-issue=
article-no=
start-page=1
end-page=9
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=20220331
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=ビジネスケース：島根県隠岐郡海?町の?政改?
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The Oki Islands, located about 60 km off the coast of the Sea of Japan, north of Shimane Prefecture, constitute an administrative division called Oki District. One of the four manned islands, Nakanoshima, which has an area of 33.43 ? and a circumference of 89.1 km, is called Ama Town as a basic municipality, and it is said that about 7,000 people lived around 1950 at its peak time. The number is, however, currently less than 2,300. The population by over 60 reaches 47.73% and the islanders call this situation a "microcosm of Japan." The climate is relatively warm, and it is a semi-agricultural and semi-fishing island. As is often the case, a traditional local food became the detonator of the island revitalization. The recent popular souvenir "Sazae Curry" was once a home-cooked dish for the islanders using turban shells and delivers the exquisiteness particular to the land and nostalgia of a sort. This is, however, memorabilia of the old days when the "Sazae" was a substitute meat for unwealthy fishermen. Today, on the contrary, the island's agriculture, forestry and fisheries has become known to deliver local specialities such as Oki beef of range cattle, farmed rock oysters from the natural coves, and squids that utilize the latest quick-freezing technology, etc. This economic restructuring is not the only achievement that the administrative reform of Ama Town has demonstrated, which also covers local finance and public education. As a business case, this paper provides a clearer picture of the process of the reform that was initiated in 2000s by the former town mayor, Michio Yamauchi.
en-copyright=
kn-copyright=

en-aut-name=TsutsuiToshimitsu
en-aut-sei=Tsutsui
en-aut-mei=Toshimitsu
kn-aut-name=筒井俊光
kn-aut-sei=筒井
kn-aut-mei=俊光
aut-affil-num=1
ORCID=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=2
ORCID=

affil-num=1
en-affil=Satosho Town Hall, General Affairs Division, Chief
kn-affil=里庄町役場 総務課主査

affil-num=2
en-affil=Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学学術研究院ヘルスシステム統合科学学域
en-keyword=Ama Town
kn-keyword=Ama Town
en-keyword=local government financial reform
kn-keyword=local government financial reform
en-keyword=public education reform
kn-keyword=public education reform
en-keyword=civic entrepreneurship
kn-keyword=civic entrepreneurship
END

start-ver=1.4
cd-journal=joma
no-vol=62
cd-vols=
no-issue=1
article-no=
start-page=35
end-page=40
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=2022
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Transformed diffuse large B-cell lymphoma from marginal zone lymphoma in the anterior mediastinum: A case report and review of the literature
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Marginal zone lymphoma (MZL) arising from the anterior mediastinum is rare. In the majority of reported cases, the tumor was incidentally discovered, reflecting its indolent clinical features. We present a 38-year-old woman who had no medical history, and presented with a bulky anterior mediastinal tumor complicated by life-threatening compression of the vasculature and bronchi. Biopsy specimens of the neoplasm suggested transformed diffuse large B-cell lymphoma (DLBCL) from MZL. To our best knowledge, this is the first case report of anterior mediastinum MZL associated with an aggressive clinical course and life-threatening complications likely due to transformation to DLBCL.
en-copyright=
kn-copyright=

en-aut-name=KitamuraWataru
en-aut-sei=Kitamura
en-aut-mei=Wataru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=AsadaNoboru
en-aut-sei=Asada
en-aut-mei=Noboru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=TabataTetsuya
en-aut-sei=Tabata
en-aut-mei=Tetsuya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=ShibataRei
en-aut-sei=Shibata
en-aut-mei=Rei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=NishiTatsuya
en-aut-sei=Nishi
en-aut-mei=Tatsuya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=KatoYuka
en-aut-sei=Kato
en-aut-mei=Yuka
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=TakasukaHiroki
en-aut-sei=Takasuka
en-aut-mei=Hiroki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=FujiwaraHideaki
en-aut-sei=Fujiwara
en-aut-mei=Hideaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=EnnishiDaisuke
en-aut-sei=Ennishi
en-aut-mei=Daisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=NishimoriHisakazu
en-aut-sei=Nishimori
en-aut-mei=Hisakazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=MatsuokaKen-Ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-Ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=KiuraKatsuyuki
en-aut-sei=Kiura
en-aut-mei=Katsuyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

en-aut-name=YoshinoTadashi
en-aut-sei=Yoshino
en-aut-mei=Tadashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=

affil-num=1
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=2
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=3
en-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=4
en-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=5
en-affil=Department of Respiratory and Allergy, Okayama University Hospital
kn-affil=

affil-num=6
en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital
kn-affil=

affil-num=7
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=8
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=9
en-affil=Center for Comprehensive Genomic Medicine, Okayama University Hospital
kn-affil=

affil-num=10
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=11
en-affil=Department of Transfusion Medicine, Okayama University Hospital
kn-affil=

affil-num=12
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=13
en-affil=Department of Respiratory and Allergy, Okayama University Hospital
kn-affil=

affil-num=14
en-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=15
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=
en-keyword=marginal zone lymphoma
kn-keyword=marginal zone lymphoma
en-keyword=diffuse large B-cell lymphoma
kn-keyword=diffuse large B-cell lymphoma
en-keyword=anterior mediastinum
kn-keyword=anterior mediastinum
en-keyword=cystic lesions
kn-keyword=cystic lesions
END

start-ver=1.4
cd-journal=joma
no-vol=60
cd-vols=
no-issue=19
article-no=
start-page=3155
end-page=3160
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20211001
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Nodal Peripheral T-cell Lymphoma with T Follicular Helper Phenotype Presenting as Chorea During Treatment: A Case Report and Literature Review
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 72-year-old man presented with chorea while undergoing treatment for recurrence of nodal peripheral T-cell lymphoma with T follicular helper (TFH) phenotype. An examination by brain N-isopropyl-p-iodoamphetamine (I-123-IMP)-single photon emission computed tomography (SPECT) revealed no abnormalities other than a decreased cerebral blood flow (CBF) in the left striatum. After four courses of salvage chemotherapy, his clinical symptoms and asymmetric cerebral perfusion improved, suggesting that the decreased CBF had caused chorea. The significance of brain SPECT has not been fully clarified in patients with chorea-associated malignant lymphoma, warranting further investigations. Brain SPECT is an alternative approach to identify abnormalities in such patients.
en-copyright=
kn-copyright=

en-aut-name=KitamuraWataru
en-aut-sei=Kitamura
en-aut-mei=Wataru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=EnnishiDaisuke
en-aut-sei=Ennishi
en-aut-mei=Daisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=YukawaRyoya
en-aut-sei=Yukawa
en-aut-mei=Ryoya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=SasakiRyo
en-aut-sei=Sasaki
en-aut-mei=Ryo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=YoshidaChikamasa
en-aut-sei=Yoshida
en-aut-mei=Chikamasa
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=TakasukaHiroki
en-aut-sei=Takasuka
en-aut-mei=Hiroki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=FujiwaraHideaki
en-aut-sei=Fujiwara
en-aut-mei=Hideaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=AsadaNoboru
en-aut-sei=Asada
en-aut-mei=Noboru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=NishimoriHisakazu
en-aut-sei=Nishimori
en-aut-mei=Hisakazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=FujiiKeiko
en-aut-sei=Fujii
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=MatsuokaKen-Ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-Ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=AbeKoji
en-aut-sei=Abe
en-aut-mei=Koji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

en-aut-name=YoshinoTadashi
en-aut-sei=Yoshino
en-aut-mei=Tadashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=

affil-num=1
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=2
en-affil=Center for Comprehensive Genomic Medicine, Okayama University Hospital
kn-affil=

affil-num=3
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=4
en-affil=Department of Neurology, Okayama University Hospital
kn-affil=

affil-num=5
en-affil=Department of Hematology, Okayama City Hospital
kn-affil=

affil-num=6
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=7
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=8
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=9
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=10
en-affil=Division of Clinical Laboratory, Okayama University Hospital
kn-affil=

affil-num=11
en-affil=Division of Blood Transfusion, Okayama University Hospital
kn-affil=

affil-num=12
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=13
en-affil=Department of Neurology, Okayama University Hospital
kn-affil=

affil-num=14
en-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=15
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=
en-keyword=peripheral T-cell lymphoma
kn-keyword=peripheral T-cell lymphoma
en-keyword=chorea
kn-keyword=chorea
en-keyword=single photon-emission computed tomography
kn-keyword=single photon-emission computed tomography
END

start-ver=1.4
cd-journal=joma
no-vol=60
cd-vols=
no-issue=17
article-no=
start-page=2831
end-page=2837
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210901
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Marginal Zone Lymphoma and Lung Adenocarcinoma with an EGFR Exon 19 E746-S752del Mutation in a Patient with IgG4-related Disease
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 68-year-old man presented with a solid mass at the left renal pelvis and ureter with multiple systemic lymphadenopathies and a mass with a cavity in the right lower lobe of the lung. While a transbronchial lung biopsy revealed no malignancy, a biopsy of the renal pelvis showed marginal zone lymphoma with polyclonal IgG4-positive cells. The serum IgG4 level and presence of a bilateral orbital mass suggested Mikulicz disease. The lesions shrank following the administration of steroids. A rebiopsy confirmed lung adenocarcinoma, and its background showed IgG4-positive cells a year later. IgG4-related diseases require careful follow-up because they can be complicated by malignancy.
en-copyright=
kn-copyright=

en-aut-name=OkawaSachi
en-aut-sei=Okawa
en-aut-mei=Sachi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=RaiKammei
en-aut-sei=Rai
en-aut-mei=Kammei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=GionYuka
en-aut-sei=Gion
en-aut-mei=Yuka
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=NinomiyaKiichiro
en-aut-sei=Ninomiya
en-aut-mei=Kiichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=KatoYuka
en-aut-sei=Kato
en-aut-mei=Yuka
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=TaniguchiAkihiko
en-aut-sei=Taniguchi
en-aut-mei=Akihiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=KuboToshio
en-aut-sei=Kubo
en-aut-mei=Toshio
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=IchiharaEiki
en-aut-sei=Ichihara
en-aut-mei=Eiki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=OhashiKadoaki
en-aut-sei=Ohashi
en-aut-mei=Kadoaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=MiyaharaNobuaki
en-aut-sei=Miyahara
en-aut-mei=Nobuaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=HottaKatsuyuki
en-aut-sei=Hotta
en-aut-mei=Katsuyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=TabataMasahiro
en-aut-sei=Tabata
en-aut-mei=Masahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=

en-aut-name=KiuraKatsuyuki
en-aut-sei=Kiura
en-aut-mei=Katsuyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=

affil-num=1
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=2
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=3
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=4
en-affil=Division of Pathophysiology, Okayama University Graduate School of Health Sciences
kn-affil=

affil-num=5
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=6
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=7
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=8
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=9
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=10
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=11
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=12
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=13
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=14
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=15
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
en-keyword=EGFR
kn-keyword=EGFR
en-keyword=IgG4-related disease
kn-keyword=IgG4-related disease
en-keyword=marginal zone lymphoma
kn-keyword=marginal zone lymphoma
en-keyword=osimertinib
kn-keyword=osimertinib
END

start-ver=1.4
cd-journal=joma
no-vol=177
cd-vols=
no-issue=
article-no=
start-page=65
end-page=76
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210826
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Perceived Value of Appropriate Vocalization for Type of Song ? An Analysis of Listening Evaluation of Elementary School Students ?
kn-title=曲種に応じた発声観の調査 ― 児童を対象とした聴取評価の分析から ―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The purpose of this study was to analyze the listening evaluation of elementary school students regarding their perceived value of appropriate vocalization for each type of song. Two strikingly different songs were selected: (1) "Hinomaru"， the educational song and (2) "Lift Your Palms Toward the Sun", a very familiar and popular song among Japanese children in and outside of Japan. In terms of vocalization, we conducted listening evaluation by presenting students with each song or sound source based on three frames of reference: (1) natural voice, (2) falsetto, and (3) sound created by artificial-voice technology. Most students perceived that the use of falsetto was suitable for "Hinomaru", while higher appropriateness scores tended to be dispersed in either natural voice or falsetto for "Let�Vs Put Our Palm to the Sunshine." Interestingly, for "Hinomaru", the number of students who reported the use of falsetto as more appropriate increased for older students in higher school years. We  peculate that this trend may be the outcome of their learning vocalization in elementary school.
en-copyright=
kn-copyright=

en-aut-name=HayakawaRinko
en-aut-sei=Hayakawa
en-aut-mei=Rinko
kn-aut-name=早川倫子
kn-aut-sei=早川
kn-aut-mei=倫子
aut-affil-num=1
ORCID=

en-aut-name=FujiiKanako
en-aut-sei=Fujii
en-aut-mei=Kanako
kn-aut-name=藤井香菜子
kn-aut-sei=藤井
kn-aut-mei=香菜子
aut-affil-num=2
ORCID=

affil-num=1
en-affil=Graduate School of Education, Okayama University
kn-affil=岡山大学大学院教育学研究科

affil-num=2
en-affil=Onomichi-city Kinosyohigashi Kindergarten
kn-affil=尾道市立木の庄東幼稚園
en-keyword=perceived value of vocalization
kn-keyword=perceived value of vocalization
en-keyword=type of song
kn-keyword=type of song
en-keyword=listening evaluation
kn-keyword=listening evaluation
en-keyword=elementary school students
kn-keyword=elementary school students
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210807
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Single domain growth and charge ordering of epitaxial YbFe2O4 films
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=YbFe2O4 is a charge-ordered ferroelectric that exhibits coupling between magnetization and electric polarization near room temperature and crystallizes in a rhombohedral structure (R3?m). This study presents an attempt to fabricate stoichiometric and epitaxial YbFe2O4-δ films with a nearly single-domain structure using an RF magnetron sputtering method. The (0001)-oriented epitaxial films of YbFe2O4-δ on YSZ (111) substrates via reactive sputtering method exhibited clear three-fold symmetry normal to the substrate without the formation of twin domains rotated by 60°. The oxygen stoichiometry of the epitaxial YbFe2O4-δ was improved by controlling an oxygen partial pressure (PO2) during the deposition. The films showed a sharp ferrimagnetic transition, and the transition temperature (TN) increased linearly to approximately 245 K with decreasing PO2. The magnitude of magnetization of the obtained films was comparable to that of bulk single crystals. Further, the electron diffraction pattern of the stoichiometric films confirmed the presence of three-dimensional charge order, which is
consistent with the behavior of the bulk crystals as well.
en-copyright=
kn-copyright=

en-aut-name=SakagamiTakumi
en-aut-sei=Sakagami
en-aut-mei=Takumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=OtaReika
en-aut-sei=Ota
en-aut-mei=Reika
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=KanoJun
en-aut-sei=Kano
en-aut-mei=Jun
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=IkedaNaoshi
en-aut-sei=Ikeda
en-aut-mei=Naoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=FujiiTatsuo
en-aut-sei=Fujii
en-aut-mei=Tatsuo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

affil-num=1
en-affil=Department of Applied Chemistry, Okayama University
kn-affil=

affil-num=2
en-affil=Department of Applied Chemistry, Okayama University
kn-affil=

affil-num=3
en-affil=Department of Applied Chemistry, Okayama University
kn-affil=

affil-num=4
en-affil=Department of Physics, Okayama University
kn-affil=

affil-num=5
en-affil=Department of Applied Chemistry, Okayama University
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=60
cd-vols=
no-issue=14
article-no=
start-page=2229
end-page=2234
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210715
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Squamous Metaplasia of the Stomach Associated with Lymphoma Infiltration
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We herein report a patient who presented with follicular lymphoma. Although the stomach was initially intact, mucosal redness and multiple erosions appeared in the gastric body owing to infiltration of the follicular lymphoma cells. Subsequently, a slightly depressed, white area lacking gastric mucosal structure was detected in the lesser curvature of the gastric cardia and body, where lymphoma cell infiltration was also pathologically observed beneath the stratified squamous epithelium. This case indicated that, although infrequent, prolonged mucosal injury owing to lymphoma infiltration can cause squamous metaplasia in the stomach.
en-copyright=
kn-copyright=

en-aut-name=IwamuroMasaya
en-aut-sei=Iwamuro
en-aut-mei=Masaya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=TanakaTakehiro
en-aut-sei=Tanaka
en-aut-mei=Takehiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=KanzakiHiromitsu
en-aut-sei=Kanzaki
en-aut-mei=Hiromitsu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=KawanoSeiji
en-aut-sei=Kawano
en-aut-mei=Seiji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=KawaharaYoshiro
en-aut-sei=Kawahara
en-aut-mei=Yoshiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=OkadaHiroyuki
en-aut-sei=Okada
en-aut-mei=Hiroyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

affil-num=1
en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=2
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=3
en-affil=Department of Pathology, Okayama University Hospital
kn-affil=

affil-num=4
en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=5
en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=6
en-affil=Department of Practical Gastrointestinal Endoscopy, Okayama University Hospital
kn-affil=

affil-num=7
en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=
en-keyword=esophagogastroduodenoscopy
kn-keyword=esophagogastroduodenoscopy
en-keyword=squamous metaplasia
kn-keyword=squamous metaplasia
en-keyword=gastrointestinal lymphoma
kn-keyword=gastrointestinal lymphoma
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=岡山県のモモ栽培における気象変動が生理障害発生に及ぼす影響の把握と対策技術の開発
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiYuichiro
en-aut-sei=Fujii
en-aut-mei=Yuichiro
kn-aut-name=藤井雄一郎
kn-aut-sei=藤井
kn-aut-mei=雄一郎
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=コーティング法による高透光性ジルコニアの強化に関する研究
kn-title=Coating method for smooth and reinforced surface layer of highly translucent zirconia
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiYoshiro
en-aut-sei=Fujii
en-aut-mei=Yoshiro
kn-aut-name=藤井惠朗
kn-aut-sei=藤井
kn-aut-mei=惠朗
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=膵癌におけるEUSの血管浸潤診断能
kn-title=Diagnostic Ability of Convex-Arrayed Endoscopic Ultrasonography for Major Vascular Invasion in Pancreatic Cancer
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiYuki
en-aut-sei=Fujii
en-aut-mei=Yuki
kn-aut-name=藤井佑樹
kn-aut-sei=藤井
kn-aut-mei=佑樹
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=60
cd-vols=
no-issue=7
article-no=
start-page=1055
end-page=1060
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210401
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Acute Kidney Injury Caused by Evans Syndrome with Systemic Lupus Erythematosus and Systemic Sclerosis
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 65-year-old woman with systemic sclerosis and systemic lupus erythematosus developed acute kidney injury (AKI), Coombs-positive autoimmune hemolytic anemia and autoimmune thrombocytopenia; therefore, she was diagnosed with Evans syndrome (ES). Intravascular hemolysis was suggested as the cause of AKI based on the presence of acute tubular injury and trace hemosiderin deposits on the renal biopsy. The renal function, hemolytic anemia and thrombocytopenia were restored by an increased dose of glucocorticoids, hemodialysis, and plasma exchange. Although ES with severe hemolytic anemia is very rare, it is important to detect possible renal dysfunction when encountering patients with severe hemolysis.
en-copyright=
kn-copyright=

en-aut-name=MatsuokaNatsumi
en-aut-sei=Matsuoka
en-aut-mei=Natsumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=WatanabeHaruki
en-aut-sei=Watanabe
en-aut-mei=Haruki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=KurookaNaoko
en-aut-sei=Kurooka
en-aut-mei=Naoko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=KatoSumari
en-aut-sei=Kato
en-aut-mei=Sumari
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=HigashiChika
en-aut-sei=Higashi
en-aut-mei=Chika
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=TanabeKatsuyuki
en-aut-sei=Tanabe
en-aut-mei=Katsuyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=KinomuraMasaru
en-aut-sei=Kinomura
en-aut-mei=Masaru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=SadaKen-Ei
en-aut-sei=Sada
en-aut-mei=Ken-Ei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=SugiyamaHitoshi
en-aut-sei=Sugiyama
en-aut-mei=Hitoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=WadaJun
en-aut-sei=Wada
en-aut-mei=Jun
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

affil-num=1
en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=2
en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=3
en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=4
en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=5
en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=6
en-affil=Division of Hemodialysis and Apheresis, Okayama University Hospital
kn-affil=

affil-num=7
en-affil=Division of Hemodialysis and Apheresis, Okayama University Hospital
kn-affil=

affil-num=8
en-affil=Department of Transfusion Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=9
en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=10
en-affil=Department of Human Resource Development of Dialysis Therapy for Kidney Disease, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=11
en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=
en-keyword=acute kidney injury
kn-keyword=acute kidney injury
en-keyword=Evans syndrome
kn-keyword=Evans syndrome
en-keyword=autoimmune hemolytic anemia
kn-keyword=autoimmune hemolytic anemia
END

start-ver=1.4
cd-journal=joma
no-vol=1
cd-vols=
no-issue=
article-no=
start-page=21
end-page=28
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210331
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Business Case: Tourism Campaigning Process of the Shimanami Kaido Expressway over the Setouchi Inner Sea in Japan
kn-title=ビジネスケース：しまなみ海道の観光資源化
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The Shimanami Kaido Expressway was visioned as a national project in the early 1970s after two tragic maritime accidents in the Setouchi Inner Sea. Since the express way connecting several islands between Hiroshima and Ehime prefecture was placed in use in 1999, it has always been a valuable means of transportation for islanders and commuters to date. In addition, with the proactive efforts made by local governments, such as Imabari City, Onomichi City, let alone with the central and prefectural governments, it has come to be acknowledged to be a sanctuary for sport cyclists. Eventually, it attracts attentions from all over Japan as a successful benchmark for both businesspeople as well as policy makers who are interested in destination management practices as part of promotion policies of reginal economies. This eventual success, however, had not been envisioned as such for a long time since the commencement of its public usage. It would rather seem that the plan had taken on its shape after a long period of many twists and turns. Furthermore, while local governments have been closely cooperating with different types of stakeholders including the actual islanders to promote the development plans, their ways of thinking are still far from unanimous. The purpose of this article is to provide business and policy students with materials that draw lessons for viewing lengthy socioeconomic processes like this case which eventually converted a nation-level, large-scale infrastructure development plan into an area-specific destination management project.
en-copyright=
kn-copyright=

en-aut-name=NakaoHikari
en-aut-sei=Nakao
en-aut-mei=Hikari
kn-aut-name=中尾光
kn-aut-sei=中尾
kn-aut-mei=光
aut-affil-num=1
ORCID=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=2
ORCID=

affil-num=1
en-affil=Japan Broadcasting Corporation
kn-affil=日本放送協会長崎放送局放送部

affil-num=2
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学大学院ヘルスシステム統合科学研究科
en-keyword=しまなみ海道
kn-keyword=しまなみ海道
en-keyword=観光資源
kn-keyword=観光資源
en-keyword=サイクリング
kn-keyword=サイクリング
en-keyword=DMO
kn-keyword=DMO
END

start-ver=1.4
cd-journal=joma
no-vol=59
cd-vols=
no-issue=19
article-no=
start-page=2415
end-page=2418
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2020
dt-pub=20201001
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Localized Lymph Node Light Chain Amyloidosis
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The prognosis of systemic amyloid light chain (AL) amyloidosis is generally poor, hence requiring chemotherapy or hematopoietic stem cell transplantation, while the prognosis of localized AL amyloidosis without an abnormal monoclonal immunoglobulin light chain is good. Localized AL amyloidosis has been previously reported to be observed in pulmonary, urinary tract, gastrointestinal, oropharyngeal, and laryngeal sites. However, only a few cases of localized lymph node AL amyloidosis have so far been reported. We herein present a case of localized lymph node AL amyloidosis that could possibly be misdiagnosed as systematic AL amyloidosis.
en-copyright=
kn-copyright=

en-aut-name=YamamotoAkira
en-aut-sei=Yamamoto
en-aut-mei=Akira
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=ObikaMikako
en-aut-sei=Obika
en-aut-mei=Mikako
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=YamashitaTaro
en-aut-sei=Yamashita
en-aut-mei=Taro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=OtsukaFumio
en-aut-sei=Otsuka
en-aut-mei=Fumio
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

affil-num=1
en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=2
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=3
en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=4
en-affil=Department of Neurology, Graduate School of Medical Sciences, Kumamoto University
kn-affil=

affil-num=5
en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
en-keyword=localized AL amyloidosis
kn-keyword=localized AL amyloidosis
en-keyword=ymphadenopathy
kn-keyword=ymphadenopathy
en-keyword=PET-CT
kn-keyword=PET-CT
en-keyword=systemic AL amyloidosis
kn-keyword=systemic AL amyloidosis
END

start-ver=1.4
cd-journal=joma
no-vol=59
cd-vols=
no-issue=16
article-no=
start-page=2023
end-page=2028
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2020
dt-pub=20200815
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Secondary Pulmonary Alveolar Proteinosis Associated with Primary Myelofibrosis and Ruxolitinib Treatment: An Autopsy Case
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Pulmonary alveolar proteinosis (PAP) is an uncommon lung disorder characterized by the excessive accumulation of surfactant-derived lipoproteins in the pulmonary alveoli and terminal bronchiole. Secondary PAP associated with primary myelofibrosis (PMF) is extremely rare, and to our knowledge, no autopsy case has been reported. We herein report an autopsy case of secondary PAP occurring in a patient with PMF who was treated with the Janus kinase 1/2 inhibitor ruxolitinib. We confirmed a diagnosis of PAP with complications based on the pathological findings at the autopsy. Notably, this case might suggest an association between ruxolitinib treatment and PAP occurrence. 
en-copyright=
kn-copyright=

en-aut-name=SugiuraHiroyuki
en-aut-sei=Sugiura
en-aut-mei=Hiroyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=NishimoriHisakazu
en-aut-sei=Nishimori
en-aut-mei=Hisakazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=NishiiKazuya
en-aut-sei=Nishii
en-aut-mei=Kazuya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=TojiTomohiro
en-aut-sei=Toji
en-aut-mei=Tomohiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=FujiiKeiko
en-aut-sei=Fujii
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=MatsuokaKen-ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=NakataKoh
en-aut-sei=Nakata
en-aut-mei=Koh
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=KiuraKatsuyuki
en-aut-sei=Kiura
en-aut-mei=Katsuyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

affil-num=1
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=2
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=3
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=4
en-affil=Department of Pathology, Okayama University Hospital
kn-affil=

affil-num=5
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=6
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=7
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=8
en-affil=Department of Bioscience Medical Research Center, Niigata University Medical & Dental Hospital
kn-affil=

affil-num=9
en-affil=Department of Allergy and Respiratory Medicine, Okayama University Hospital
kn-affil=

affil-num=10
en-affil=Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
en-keyword=pulmonary alveolar proteinosis
kn-keyword=pulmonary alveolar proteinosis
en-keyword=primary myelofibrosis
kn-keyword=primary myelofibrosis
en-keyword=autopsy
kn-keyword=autopsy
en-keyword=ruxolitinib
kn-keyword=ruxolitinib
END

start-ver=1.4
cd-journal=joma
no-vol=59
cd-vols=
no-issue=21
article-no=
start-page=2757
end-page=2761
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2020
dt-pub=20201101
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Adult T-cell Leukemia-lymphoma with Primary Breast Involvement: A Case Report and Literature Review
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Breast involvement of Adult T-cell leukemia-lymphoma (ATLL) is extremely rare, and the data on the characteristics are limited. We herein describe a 49-year-old woman who presented with skin involvement of ATLL. Positron emission tomography/computed tomography showed bilateral breast lesions. Although the patient once achieved a complete metabolic response, a relapse of her ATLL occurred. The patient received subsequent allogeneic hematopoietic stem cell transplantation (HSCT). To our knowledge, only four cases of ATLL with breast involvement have previously been reported, and the prognoses have generally been poor. Breast lesions of ATLL have aggressive features, and intensive systemic chemotherapy and HSCT are required to improve survival. 
en-copyright=
kn-copyright=

en-aut-name=KobayashiHiroki
en-aut-sei=Kobayashi
en-aut-mei=Hiroki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=AsadaNoboru
en-aut-sei=Asada
en-aut-mei=Noboru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=IgawaTakuro
en-aut-sei=Igawa
en-aut-mei=Takuro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=AbeMasaya
en-aut-sei=Abe
en-aut-mei=Masaya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=MeguriYusuke
en-aut-sei=Meguri
en-aut-mei=Yusuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=EnnishiDaisuke
en-aut-sei=Ennishi
en-aut-mei=Daisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=NishimoriHisakazu
en-aut-sei=Nishimori
en-aut-mei=Hisakazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=MatsuokaKen-ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=YoshinoTadashi
en-aut-sei=Yoshino
en-aut-mei=Tadashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

affil-num=1
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=2
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=3
en-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=4
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=5
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=6
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=7
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=8
en-affil=Department of Transfusion Medicine, Okayama University Hospital
kn-affil=

affil-num=9
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=

affil-num=10
en-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
kn-affil=

affil-num=11
en-affil=Department of Hematology and Oncology, Okayama University Hospital
kn-affil=
en-keyword=adult T-cell leukemia-lymphoma
kn-keyword=adult T-cell leukemia-lymphoma
en-keyword=breast involvement
kn-keyword=breast involvement
en-keyword=positron emission tomography/computed tomography
kn-keyword=positron emission tomography/computed tomography
END

start-ver=1.4
cd-journal=joma
no-vol=132
cd-vols=
no-issue=2
article-no=
start-page=87
end-page=90
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2020
dt-pub=20200803
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of paraneoplastic neurological syndrome associated with Hodgkin lymphoma
kn-title=ホジキンリンパ腫の治療により神経症状の改善を認めた傍腫瘍性神経症候群の1 例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=　An 86-year-old man was admitted to another hospital with ataxia and general fatigue. Brain MRI scan revealed a high-intensity area in the bilateral thalamus, and he was referred to Okayama University Hospital for detailed examination. Cerebrospinal fluid (CSF) and blood tests showed no evidence of infection or autoimmune encephalitis. An FDG-PET/CT scan revealed systemic lymphadenopathy, and cervical lymph node biopsy showed classical Hodgkin lymphoma. Neurological symptoms were suspicious of paraneoplastic neurological syndrome (PNS), but onco-neural antibodies were not detected in either serum or CSF. He was referred to our hospital, Okayama Red Cross Hospital, for treatment and administered 6 cycles of an ABVD regimen, and an FDG-PET/CT scan showed a complete remission. The brain lesion disappeared and neurological symptoms were improved, so he was diagnosed with PNS. PNS is rare complication associated with malignant lymphoma and early diagnosis is important because neurological symptoms can be improved with anti-cancer treatment. 
en-copyright=
kn-copyright=

en-aut-name=IkemachiRyosuke
en-aut-sei=Ikemachi
en-aut-mei=Ryosuke
kn-aut-name=池町涼介
kn-aut-sei=池町
kn-aut-mei=涼介
aut-affil-num=1
ORCID=

en-aut-name=KondoKaho
en-aut-sei=Kondo
en-aut-mei=Kaho
kn-aut-name=近藤歌穂 
kn-aut-sei=近藤
kn-aut-mei=歌穂 
aut-affil-num=2
ORCID=

en-aut-name=MatumuraAkihumi
en-aut-sei=Matumura
en-aut-mei=Akihumi
kn-aut-name=松村彰文
kn-aut-sei=松村
kn-aut-mei=彰文
aut-affil-num=3
ORCID=

en-aut-name=FujiiSoichiro
en-aut-sei=Fujii
en-aut-mei=Soichiro
kn-aut-name=藤井総一郎
kn-aut-sei=藤井
kn-aut-mei=総一郎
aut-affil-num=4
ORCID=

en-aut-name=TakeuchiMakoto
en-aut-sei=Takeuchi
en-aut-mei=Makoto
kn-aut-name=竹内誠
kn-aut-sei=竹内
kn-aut-mei=誠
aut-affil-num=5
ORCID=

en-aut-name=SatoKouta
en-aut-sei=Sato
en-aut-mei=Kouta
kn-aut-name=佐藤恒太
kn-aut-sei=佐藤
kn-aut-mei=恒太
aut-affil-num=6
ORCID=

en-aut-name=AbeKoji
en-aut-sei=Abe
en-aut-mei=Koji
kn-aut-name=阿部康二
kn-aut-sei=阿部
kn-aut-mei=康二
aut-affil-num=7
ORCID=

en-aut-name=YoshinoTadashi
en-aut-sei=Yoshino
en-aut-mei=Tadashi
kn-aut-name=吉野正
kn-aut-sei=吉野
kn-aut-mei=正
aut-affil-num=8
ORCID=

affil-num=1
en-affil=Department of Hematology, Okayama Red Cross Hospital
kn-affil=岡山赤十字病院　血液内科 

affil-num=2
en-affil=Department of Hematology, Okayama Red Cross Hospital 
kn-affil=岡山赤十字病院　血液内科 

affil-num=3
en-affil=Department of Hematology, Okayama Red Cross Hospital 
kn-affil=岡山赤十字病院　血液内科 

affil-num=4
en-affil=Department of Hematology, Okayama Red Cross Hospital 
kn-affil=岡山赤十字病院　血液内科 

affil-num=5
en-affil=Department of Hematology, Okayama Red Cross Hospital
kn-affil=岡山赤十字病院　血液内科 

affil-num=6
en-affil=Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=岡山大学大学院医歯薬学総合研究科　脳神経内科学 

affil-num=7
en-affil=Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=岡山大学大学院医歯薬学総合研究科　脳神経内科学

affil-num=8
en-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=岡山大学大学院医歯薬学総合研究科　病理学（腫瘍病理）
en-keyword=傍腫瘍性神経症候群 (paraneoplastic neurological syndrome)
kn-keyword=傍腫瘍性神経症候群 (paraneoplastic neurological syndrome)
en-keyword=悪性リンパ腫 (malignant lymphoma)
kn-keyword=悪性リンパ腫 (malignant lymphoma)
END

start-ver=1.4
cd-journal=joma
no-vol=10
cd-vols=
no-issue=1
article-no=
start-page=17237
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2020
dt-pub=20201014
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=5-aminolevulinic acid-mediated photodynamic therapy can target aggressive adult T cell leukemia/lymphoma resistant to conventional chemotherapy
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Photodynamic therapy (PDT) is an emerging treatment for various solid cancers. We recently reported that tumor cell lines and patient specimens from adult T cell leukemia/lymphoma (ATL) are susceptible to specific cell death by visible light exposure after a short-term culture with 5-aminolevulinic acid, indicating that extracorporeal photopheresis could eradicate hematological tumor cells circulating in peripheral blood. As a bridge from basic research to clinical trial of PDT for hematological malignancies, we here examined the efficacy of ALA-PDT on various lymphoid malignancies with circulating tumor cells in peripheral blood. We also examined the effects of ALA-PDT on tumor cells before and after conventional chemotherapy. With 16 primary blood samples from 13 patients, we demonstrated that PDT efficiently killed tumor cells without influencing normal lymphocytes in aggressive diseases such as acute ATL. Importantly, PDT could eradicate acute ATL cells remaining after standard chemotherapy or anti-CCR4 antibody, suggesting that PDT could work together with other conventional therapies in a complementary manner. The responses of PDT on indolent tumor cells were various but were clearly depending on accumulation of protoporphyrin IX, which indicates the possibility of biomarker-guided application of PDT. These findings provide important information for developing novel therapeutic strategy for hematological malignancies.
en-copyright=
kn-copyright=

en-aut-name=SandoYasuhisa
en-aut-sei=Sando
en-aut-mei=Yasuhisa
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=MatsuokaKen-Ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-Ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=SumiiYuichi
en-aut-sei=Sumii
en-aut-mei=Yuichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=KondoTakumi
en-aut-sei=Kondo
en-aut-mei=Takumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=IkegawaShuntaro
en-aut-sei=Ikegawa
en-aut-mei=Shuntaro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=SugiuraHiroyuki
en-aut-sei=Sugiura
en-aut-mei=Hiroyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=NakamuraMakoto
en-aut-sei=Nakamura
en-aut-mei=Makoto
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=IwamotoMiki
en-aut-sei=Iwamoto
en-aut-mei=Miki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=MeguriYusuke
en-aut-sei=Meguri
en-aut-mei=Yusuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=AsadaNoboru
en-aut-sei=Asada
en-aut-mei=Noboru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=EnnishiDaisuke
en-aut-sei=Ennishi
en-aut-mei=Daisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=NishimoriHisakazu
en-aut-sei=Nishimori
en-aut-mei=Hisakazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=FujiiKeiko
en-aut-sei=Fujii
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=

en-aut-name=UtsunomiyaAtae
en-aut-sei=Utsunomiya
en-aut-mei=Atae
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=

en-aut-name=OkaTakashi
en-aut-sei=Oka
en-aut-mei=Takashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=16
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=17
ORCID=

affil-num=1
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=2
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=3
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=4
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=5
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=6
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=7
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=8
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=9
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=10
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=11
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=12
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=13
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=14
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=15
en-affil=Department of Hematology, Imamura General Hospital
kn-affil=

affil-num=16
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=17
en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
en-keyword=T-cell lymphoma
kn-keyword=T-cell lymphoma
en-keyword=Targeted therapies
kn-keyword=Targeted therapies
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=8
article-no=
start-page=51
end-page=63
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1980
dt-pub=19800301
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=資料翻刻　松の屋旧蔵『湖月抄』の書入れ注記――藤井高尚の源氏物語研究――
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=工藤進思郎
kn-aut-sei=工藤
kn-aut-mei=進思郎
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=小橋和恵
kn-aut-sei=小橋
kn-aut-mei=和恵
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学法文学部

affil-num=2
en-affil=
kn-affil=岡山大学大学院文学研究科終了
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=9
article-no=
start-page=71
end-page=80
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810301
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=藤井高尚判『十七番歌合』について――解説と翻刻――
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=工藤進思郎
kn-aut-sei=工藤
kn-aut-mei=進思郎
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学文学部
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=12
article-no=
start-page=144
end-page=154
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1984
dt-pub=19840331
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=藤井高尚の鈴の屋入門――本居宣長との交渉をめぐって――
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=工藤進思郎
kn-aut-sei=工藤
kn-aut-mei=進思郎
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学文学部
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=16
article-no=
start-page=79
end-page=89
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1988
dt-pub=19880331
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=藤井高尚文題索引
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=工藤進思郎
kn-aut-sei=工藤
kn-aut-mei=進思郎
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=19
article-no=
start-page=64
end-page=74
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1991
dt-pub=19910331
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=藤井高尚の紀行文―『山つと』を中心として―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=工藤進思郎
kn-aut-sei=工藤
kn-aut-mei=進思郎
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学文学部
END

start-ver=1.4
cd-journal=joma
no-vol=10
cd-vols=
no-issue=1
article-no=
start-page=10702
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2020
dt-pub=20200701
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Skewed electronic band structure induced by electric polarization in ferroelectric BaTiO3
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Skewed band structures have been empirically described in ferroelectric materials to explain the functioning of recently developed ferroelectric tunneling junction (FTJs). Nonvolatile ferroelectric random access memory (FeRAM) and the artificial neural network device based on the FTJ system are rapidly developing. However, because the actual ferroelectric band structure has not been elucidated, precise designing of devices has to be advanced through appropriate heuristics. Here, we perform angle-resolved hard X-ray photoemission spectroscopy of ferroelectric BaTiO3 thin films for the direct observation of ferroelectric band skewing structure as the depth profiles of atomic orbitals. The depth-resolved electronic band structure consists of three depth regions: a potential slope along the electric polarization in the core, the surface and interface exhibiting slight changes. We also demonstrate that the direction of the energy shift is controlled by the polarization reversal. In the ferroelectric skewed band structure, we found that the difference in energy shifts of the atomic orbitals is correlated with the atomic configuration of the soft phonon mode reflecting the Born effective charges. These findings lead to a better understanding of the origin of electric polarization.
en-copyright=
kn-copyright=

en-aut-name=OshimeNorihiro
en-aut-sei=Oshime
en-aut-mei=Norihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=KanoJun
en-aut-sei=Kano
en-aut-mei=Jun
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=IkenagaEiji
en-aut-sei=Ikenaga
en-aut-mei=Eiji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=YasuiShintaro
en-aut-sei=Yasui
en-aut-mei=Shintaro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=HamasakiYosuke
en-aut-sei=Hamasaki
en-aut-mei=Yosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=YasuharaSou
en-aut-sei=Yasuhara
en-aut-mei=Sou
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=HinokumaSatoshi
en-aut-sei=Hinokuma
en-aut-mei=Satoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=IkedaNaoshi
en-aut-sei=Ikeda
en-aut-mei=Naoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=JanolinPierre-Eymeric
en-aut-sei=Janolin
en-aut-mei=Pierre-Eymeric
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=KiatJean-Michel
en-aut-sei=Kiat
en-aut-mei=Jean-Michel
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=ItohMitsuru
en-aut-sei=Itoh
en-aut-mei=Mitsuru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=YokoyaTakayoshi
en-aut-sei=Yokoya
en-aut-mei=Takayoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=FujiiTatsuo
en-aut-sei=Fujii
en-aut-mei=Tatsuo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

en-aut-name=YasuiAkira
en-aut-sei=Yasui
en-aut-mei=Akira
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=

en-aut-name=OsawaHitoshi
en-aut-sei=Osawa
en-aut-mei=Hitoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=

affil-num=1
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=2
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=3
en-affil=Japan Synchrotron Radiation Research Institute, JASRI
kn-affil=

affil-num=4
en-affil=Laboratory for Materials and Structures, Tokyo Institute of Technology
kn-affil=

affil-num=5
en-affil=Laboratory for Materials and Structures, Tokyo Institute of Technology
kn-affil=

affil-num=6
en-affil=Laboratory for Materials and Structures, Tokyo Institute of Technology
kn-affil=

affil-num=7
en-affil=Innovative Oxidation Team, Interdisciplinary Research Center for Catalytic Chemistry, National Institute of Advanced Industrial Science and Technology
kn-affil=

affil-num=8
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=9
en-affil=Universit? Paris-Saclay,CentraleSup?lec, CNRS, Laboratoire SPMS
kn-affil=

affil-num=10
en-affil=Universit? Paris-Saclay,CentraleSup?lec, CNRS, Laboratoire SPMS
kn-affil=

affil-num=11
en-affil=Laboratory for Materials and Structures, Tokyo Institute of Technology
kn-affil=

affil-num=12
en-affil=GResearch Institute for Interdisciplinary Science, Okayama University
kn-affil=

affil-num=13
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=14
en-affil=Japan Synchrotron Radiation Research Institute, JASRI
kn-affil=

affil-num=15
en-affil=Japan Synchrotron Radiation Research Institute, JASRI
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=132
cd-vols=
no-issue=1
article-no=
start-page=34
end-page=36
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2020
dt-pub=20200401
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Chimeric antigen receptor (CAR)-T cell therapy
kn-title=キメラ抗原受容体導入Ｔ細胞（CAR-T）療法
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=藤井伸治
kn-aut-sei=藤井
kn-aut-mei=伸治
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Division of Blood Transfusion, Okayama University Hospital
kn-affil=岡山大学病院　輸血部
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=
dt-pub=
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Hypericum oliganthum Franch. et Sav.
kn-title=アゼオトギリ
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-keyword=オトギリソウ科 (Hypericaceae)
kn-keyword=オトギリソウ科 (Hypericaceae)
END

start-ver=1.4
cd-journal=joma
no-vol=10
cd-vols=
no-issue=
article-no=
start-page=107
end-page=121
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2020
dt-pub=20200320
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Implementing a Professional Learning Community(PLC) at Special Needs Schools Focus on the Relationships among the PLC, the Curriculum Management and the Realization of passing on expertise
kn-title=特別支援学校における「専門職の学習共同体」の醸成 : カリキュラム・マネジメントおよび専門性の継承・向上の実現との関係性に着目して
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract= 全国の特別支援学校〔聴覚障害部門〕を対象に，カリキュラム・マネジメントの実施や「専門職の学習共同体」の醸成，専門性の継承・向上の実現に関する質問紙調査を行った。収集したデータをもとに相互の関係性を分析した結果，「専門職の学習共同体」を醸成している学校においては専門性を継承・向上している実感が高いことが明らかとなった。また，実施するカリキュラム・マネジメントの質（内容）として「カリキュラムの『見える化』と共有の場づくり」，「カリキュラム開発のための協働の場づくり」等のカリキュラムを基軸に教職員間のつながりを深める取組を行っている学校においては，「専門職の学習共同体」の構成因子のうち「学校内の信頼関係」，「目標の共有」，「学校内外の協働」が醸成されていることが示された。このことから「専門職の学習共同体」を効果的に醸成していくためには，質の高いカリキュラム・マネジメントを実施する必要性が示唆された。
en-copyright=
kn-copyright=

en-aut-name=FUJIIYushi
en-aut-sei=FUJII
en-aut-mei=Yushi
kn-aut-name=藤井裕士
kn-aut-sei=藤井
kn-aut-mei=裕士
aut-affil-num=1
ORCID=

en-aut-name=KumagaiShinnosuke
en-aut-sei=Kumagai
en-aut-mei=Shinnosuke
kn-aut-name=熊谷愼之輔
kn-aut-sei=熊谷
kn-aut-mei=愼之輔
aut-affil-num=2
ORCID=

en-aut-name=MisawaRyo
en-aut-sei=Misawa
en-aut-mei=Ryo
kn-aut-name=三沢良
kn-aut-sei=三沢
kn-aut-mei=良
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院教育学研究科

affil-num=2
en-affil=Graduate School of Education, Okayama University
kn-affil=岡山大学大学院教育学研究科

affil-num=3
en-affil=Graduate School of Education, Okayama University
kn-affil=岡山大学大学院教育学研究科
en-keyword=専門職の学習共同体 (Professional Learning Community)
kn-keyword=専門職の学習共同体 (Professional Learning Community)
en-keyword=特別支援学校版PLC構成因子 (PLC index of Special Needs Schools)
kn-keyword=特別支援学校版PLC構成因子 (PLC index of Special Needs Schools)
en-keyword=カリキュラム・マネジメント (Curriculum Manag ement)
kn-keyword=カリキュラム・マネジメント (Curriculum Manag ement)
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=2380179
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2018
dt-pub=20180314
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Serum Procalcitonin Levels in Acute Encephalopathy with Biphasic Seizures and Late Reduced Diffusion
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Procalcitonin (PCT) is used as a biomarker in severe infections. Here, we retrospectively investigated levels of serum PCT, C-reactive protein (CRP), and inflammatory cytokines (IL-6, TNF-alpha, and IFN-gamma) in the second phase of patients with acute encephalopathy with biphasic seizures and late reduced diffusion (AESD). Nine AESD pediatric patients (4 men, 5 women; AESD group) admitted to Okayama University Hospital from 2010 to 2016 were compared with 10 control patients with febrile seizures (FS) (3 men, 7 women; FS group). Mean PCT concentrations (ng/mL) in the AESD and FS groups were significantly different, at 9.8 +/- 6.7 and 0.8 +/- 0.9, respectively (p = 0 0006). CRP (mg/dL) were 0.79 +/- 0.89 and 1.4 +/- 1.0 (p = 0 94), respectively; IL-6 (pg/mL) were 449.7 +/- 705.0 and 118.3 +/- 145.4 (p = 0 20), respectively; TNF-alpha (pg/mL) were 18.6 +/- 12.5 and 16.6 +/- 6.0 (p = 0 67), respectively; and IFN-gamma (pg/mL) were 79.6 +/- 158.5 and 41.9 +/- 63.7 (p = 0 56), respectively. Ratios of PCT to CRP were 27.5 +/- 34.2 and 3.2 +/- 6.8 (p < 0 0001), respectively. The sensitivity and specificity in the diagnosis of AESD using a cutoff of PCT/CRP ratio of 1.0 were 79% and 100%, respectively. These results suggest that PCT and the PCT/CRP ratio are useful in auxiliary diagnosis of the second stage of AESD, and in AESD, PCT is likely to increase through a different mechanism.
en-copyright=
kn-copyright=

en-aut-name=FujiiYosuke
en-aut-sei=Fujii
en-aut-mei=Yosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=YashiroMasato
en-aut-sei=Yashiro
en-aut-mei=Masato
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=YamadaMutsuko
en-aut-sei=Yamada
en-aut-mei=Mutsuko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=KikkawaTomonobu
en-aut-sei=Kikkawa
en-aut-mei=Tomonobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=NosakaNobuyuki
en-aut-sei=Nosaka
en-aut-mei=Nobuyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=SaitoYukie
en-aut-sei=Saito
en-aut-mei=Yukie
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=TsukaharaKohei
en-aut-sei=Tsukahara
en-aut-mei=Kohei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=IkedaMasanori
en-aut-sei=Ikeda
en-aut-mei=Masanori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=MorishimaTsuneo
en-aut-sei=Morishima
en-aut-mei=Tsuneo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=TsukaharaHirokazu
en-aut-sei=Tsukahara
en-aut-mei=Hirokazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

affil-num=1
en-affil=Department of Pediatric Acute Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=2
en-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=3
en-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=4
en-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=5
en-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=6
en-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=7
en-affil=Department of Emergency and Critical Care Medicine, Okayama University Graduate School of Medicine, Dentistry and
kn-affil=

affil-num=8
en-affil=Department of Pediatric Acute Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=9
en-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=10
en-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=9
cd-vols=
no-issue=7
article-no=
start-page=783
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190712
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Effect of Lubrication and Forging Load on Surface Roughness, Residual Stress, and Deformation of Cold Forging Tools
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Cold forging is a metal forming that which uses localized compressive force at room temperature. During the cold forging process, the tool is subjected to extremely high loads and abrasive wear. Lubrication plays an important role in cold forging to improve product quality and tool life by preventing direct metallic contact. Surface roughness and residual stress also greatly affects the service life of a tool. In this study, variations in surface roughness, residual stress, and specimen deformation with the number of cold forging cycles were investigated under different forging conditions. Specimens that were made of heat-treated SKH51 (59-61 HRC), a high-speed tool steel with a polished working surface, were used. The specimens were subjected to an upsetting process. Compressive residual stress, surface roughness, and specimen deformation showed a positive relationship with the number of forging cycles up to a certain limit and became almost constant in most of the forging conditions. A larger change in residual stress and surface roughness was observed at the center of the specimens in all the forging conditions. The effect of the magnitude of the forging load on the above discussed parameters is large when compared to the effect of the lubrication conditions.
en-copyright=
kn-copyright=

en-aut-name=KarunathilakaNuwan
en-aut-sei=Karunathilaka
en-aut-mei=Nuwan
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=TadaNaoya
en-aut-sei=Tada
en-aut-mei=Naoya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=UemoriTakeshi
en-aut-sei=Uemori
en-aut-mei=Takeshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=HanamitsuRyota
en-aut-sei=Hanamitsu
en-aut-mei=Ryota
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=FujiiMasahiro
en-aut-sei=Fujii
en-aut-mei=Masahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=OmiyaYuya
en-aut-sei=Omiya
en-aut-mei=Yuya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=KawanoMasahiro
en-aut-sei=Kawano
en-aut-mei=Masahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

affil-num=1
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=2
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=3
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=4
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=5
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=6
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=7
en-affil=Zeno Tech Co., Ltd
kn-affil=
en-keyword=cold forging
kn-keyword=cold forging
en-keyword=high-speed tool steel
kn-keyword=high-speed tool steel
en-keyword=lubrication
kn-keyword=lubrication
en-keyword=residual stress
kn-keyword=residual stress
en-keyword=surface roughness
kn-keyword=surface roughness
en-keyword=tool deformation
kn-keyword=tool deformation
END

start-ver=1.4
cd-journal=joma
no-vol=9
cd-vols=
no-issue=
article-no=
start-page=8041
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=2019529
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Intermittent parathyroid hormone 1-34 induces oxidation and deterioration of mineral and collagen quality in newly formed mandibular bone
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Intermittent parathyroid hormone (PTH) administration is known to promote bone healing after surgical procedures. However, the mechanism and influence of PTH on the mineral and collagen quality of the jaw are not well understood. Most studies have focused on analyzing the bone density and microstructure of the mandible, and have insufficiently investigated its mineral and collagen quality. Oxidative stress activates osteoclasts, produces advanced glycation end products, and worsens mineral and collagen quality. We hypothesized that PTH induces oxidation and affects the mineral and collagen quality of newly formed mandibular bone. To test this, we examined the mineral and collagen quality of newly formed mandibular bone in rats administered PTH, and analyzed serum after intermittent PTH administration to examine the degree of oxidation. PTH administration reduced mineralization and worsened mineral and collagen quality in newly formed bone. In addition, total anti-oxidant capacity in serum was significantly decreased and the oxidative-INDEX was increased among PTH-treated compared to vehicle-treated rats, indicating serum oxidation. In conclusion, intermittent administration of PTH reduced mineral and collagen quality in newly formed mandibular bone. This effect may have been induced by oxidation.
en-copyright=
kn-copyright=

en-aut-name=YoshiokaYohsuke
en-aut-sei=Yoshioka
en-aut-mei=Yohsuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=YamachikaEiki
en-aut-sei=Yamachika
en-aut-mei=Eiki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=NakanishiMakoto
en-aut-sei=Nakanishi
en-aut-mei=Makoto
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=NinomiyaTadashi
en-aut-sei=Ninomiya
en-aut-mei=Tadashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=AkashiSho
en-aut-sei=Akashi
en-aut-mei=Sho
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=KondoSei
en-aut-sei=Kondo
en-aut-mei=Sei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=MoritaniNorifumi
en-aut-sei=Moritani
en-aut-mei=Norifumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=KobayashiYasuhiro
en-aut-sei=Kobayashi
en-aut-mei=Yasuhiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=FujiiTatsuo
en-aut-sei=Fujii
en-aut-mei=Tatsuo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=IidaSeiji
en-aut-sei=Iida
en-aut-mei=Seiji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

affil-num=1
en-affil=Department of Oral and Maxillofacial Reconstructive Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=2
en-affil=Department of Oral and Maxillofacial Reconstructive Surgery, Okayama University Hospital
kn-affil=

affil-num=3
en-affil=Department of Applied Chemistry, Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=4
en-affil=Department of Anatomy, Nihon University School of Dentistry
kn-affil=

affil-num=5
en-affil=Department of Oral and Maxillofacial Reconstructive Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=6
en-affil=Department of Oral and Maxillofacial Reconstructive Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=7
en-affil=Department of Oral and Maxillofacial Reconstructive Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=8
en-affil=Division of Hard Tissue Research, Institute for Oral Science, Matsumoto Dental University
kn-affil=

affil-num=9
en-affil=Department of Applied Chemistry, Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=10
en-affil=Department of Oral and Maxillofacial Reconstructive Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=172
cd-vols=
no-issue=
article-no=
start-page=1
end-page=9
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20191127
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=「専門職の学習共同体」としての学校の実現をめざしたカリキュラム・マネジメントに関する基礎研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=　本研究は，「専門職の学習共同体（以下：PLC）」としての学校の実現をめざしたカリキュラム・マネジメント（以下：CM）による実践研究を行うに当たって理論的な枠組みを構築することを目的とした。ベテラン教員の大量退職を控え，国内の多くの学校では専門性の継承・向上が課題とされている。それを教職員個人の問題として，個人の専門性のみに着目するのではなく，学校が組織として専門性を継承・向上できるようなPLCとしての学校文化を醸成していくことが重要であると考えた。そういった学校文化を醸成するためのヒントを，Sheinの文化の学習／変容のモデルから得て，PLCとしての学校文化変革のためのCMのプロセスを提案した。
en-copyright=
kn-copyright=

en-aut-name=KumagaiShinnosuke
en-aut-sei=Kumagai
en-aut-mei=Shinnosuke
kn-aut-name=熊谷愼之輔
kn-aut-sei=熊谷
kn-aut-mei=愼之輔
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井裕士
kn-aut-sei=藤井
kn-aut-mei=裕士
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院教育学研究科

affil-num=2
en-affil=
kn-affil=岡山大学大学院教育学研究科　教職実践専攻
en-keyword=専門職の学習共同体
kn-keyword=専門職の学習共同体
en-keyword=カリキュラム・マネジメント
kn-keyword=カリキュラム・マネジメント
en-keyword=特別支援学校
kn-keyword=特別支援学校
en-keyword=専門性の継承・向上
kn-keyword=専門性の継承・向上
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190925
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=−腸内細菌叢解析およびメタボローム解析による評価−
kn-title=アルツハイマー型認知症患者の腸内細菌叢によるヒト型モデルマウスの構築とこの構築マウスの認知行動に腸内環境が及ぼす影響
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiYusuke
en-aut-sei=Fujii
en-aut-mei=Yusuke
kn-aut-name=藤井祐介
kn-aut-sei=藤井
kn-aut-mei=祐介
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=岡山大学大学院環境生命科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=
article-no=
start-page=1
end-page=15
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190628
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=地方社会解体の危機に抗するCSAの可能性 : ＜鳴子の米プロジェエクト＞を事例として
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiWasa
en-aut-sei=Fujii
en-aut-mei=Wasa
kn-aut-name=藤井和佐
kn-aut-sei=藤井
kn-aut-mei=和佐
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院社会文化科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2018
dt-pub=20181227
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=痙攣重積型脳症における血清プロカルシトニンの検討
kn-title=Serum Procalcitonin Levels in Acute Encephalopathy with Biphasic Seizures and Late Reduced Diffusion
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiYosuke
en-aut-sei=Fujii
en-aut-mei=Yosuke
kn-aut-name=藤井洋輔
kn-aut-sei=藤井
kn-aut-mei=洋輔
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=
article-no=
start-page=1
end-page=11
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2018
dt-pub=20181126
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Toward a J-Form Theory of Knowledge-Creating Firms
kn-title=日本型知識創造の理論構築を目指して
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院大学院ヘルスシステム統合科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=50
cd-vols=
no-issue=2
article-no=
start-page=1
end-page=10
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2018
dt-pub=20181107
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Socio-Psychological Impacts of Minoriry in Majoriry: A Preliminary Test
kn-title=多数派内少数者の影響力：予備的考察
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=MoriyaKakeru
en-aut-sei=Moriya
en-aut-mei=Kakeru
kn-aut-name=守矢翔
kn-aut-sei=守矢
kn-aut-mei=翔
aut-affil-num=1
ORCID=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=

affil-num=2
en-affil=
kn-affil=岡山大学大学院ヘルスシステム統合科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=20171227
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=消化管原発びまん性大細胞型B細胞リンパ腫におけるA20 (TNFAIP3) 遺伝子異常
kn-title=A20 (TNFAIP3) Alterations in Primary Intestinal Diffuse Large B-cell Lymphoma
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiMasayoshi
en-aut-sei=Fujii
en-aut-mei=Masayoshi
kn-aut-name=藤井将義
kn-aut-sei=藤井
kn-aut-mei=将義
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=49
cd-vols=
no-issue=2
article-no=
start-page=75
end-page=81
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2018
dt-pub=20180226
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Self-Restructuring Process through Utilization of External Organization in Public Sector: A Preliminary Thought
kn-title=公共部門の外部組織利用を通じた自己革新プロセスに関する予備的考察
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=大学院社会文化科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=107
cd-vols=
no-issue=
article-no=
start-page=5
end-page=10
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2018
dt-pub=20180201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Alzheimer’s disease : Relationship between the Alzheimer’s disease and human microbiome
kn-title=アルツハイマー病の背景と発症 : ヒトマイクロバイオーム（細菌叢）との関連の視点から
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract= Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized by memory and language disorder. The accumulation of senile plaques called β-amyloid and neurofibrillary tangles involving protein tau in the brains of AD patients have been considered as two hallmarks of AD. In AD, it is reported that accumulation of β-amyloid may be observed 25 years before onset, supporting early diagnosis and treatment by brain image analysis, because several techniques have recently been developed to detect β-amyloid and tau protein in brains of persons diagnosed with AD. AD patients are usually suffering from other diseases such as diabetes or periodontal disease, and there is accumulating data to show that these diseases associate with the human microbiome, such as gut and oral microbiota. In this report, the relation ship between AD and the human microbiome is reviewed.
en-copyright=
kn-copyright=

en-aut-name=FujiiYusuke
en-aut-sei=Fujii
en-aut-mei=Yusuke
kn-aut-name=藤井祐介
kn-aut-sei=藤井
kn-aut-mei=祐介
aut-affil-num=1
ORCID=

en-aut-name=MoritaHidetoshi
en-aut-sei=Morita
en-aut-mei=Hidetoshi
kn-aut-name=森田英利
kn-aut-sei=森田
kn-aut-mei=英利
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院　環境生命科学研究科

affil-num=2
en-affil=
kn-affil=岡山大学大学院　環境生命科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=129
cd-vols=
no-issue=3
article-no=
start-page=155
end-page=157
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=20171201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The 2016 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2016 Sunada Prize)
kn-title=平成28年度岡山医学会賞 胸部・循環研究奨励賞（砂田賞）
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiUtako
en-aut-sei=Fujii
en-aut-mei=Utako
kn-aut-name=藤井詩子
kn-aut-sei=藤井
kn-aut-mei=詩子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Department of Internal Medicine, Fukuyama City Hospital
kn-affil=福山市民病院　内科
END

start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=4
article-no=
start-page=315
end-page=323
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=201708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Residual Femoral Deformity and Femoroacetabular Impingement after Intertrochanteric Osteotomy for Slipped Capital Femoral Epiphysis
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We retrospectively reviewed 29 hips in which intertrochanteric osteotomies were performed for severe slipped capital femoral epiphyses. Mean age at surgery: 12.6 years. Mean follow-up period: 6 years. At the final follow-up evaluation, one patient had coxalgia, and six hips showed a limited range of motion. A pistol-grip deformity was observed in 13 hips, osteoarthritis in two hips, and a bump existed in 19 hips on the latest radiographs. Gradual remodeling of the bumps was observed post-operatively in 22 hips. The mean α and β angles and offset α and β improved over time. The remodeling proceeded rapidly for 1 year post-surgery. We compared hips classified as β angles of ? 63° to < 63° at the final follow-up evaluation, the mean β angle 1 year post-surgery, and the mean ratio of improvement of the β angle per year from 1 year post-surgery to the final follow up, which differed significantly. Nearly all of the patients who underwent intertrochanteric osteotomies had residual morphologic abnormalities, but few had clinical symptoms. The β angle 1 year post-surgery and the ratio of remodeling of the bump from 1 year post-surgery to the final follow-up can be regarded as a potential predictor of morphologic results after intertrochanteric osteotomy.
en-copyright=
kn-copyright=

en-aut-name=FujiiYosuke
en-aut-sei=Fujii
en-aut-mei=Yosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=EndoHirosuke
en-aut-sei=Endo
en-aut-mei=Hirosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=MitaniShigeru
en-aut-sei=Mitani
en-aut-mei=Shigeru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=AkazawaHirofumi
en-aut-sei=Akazawa
en-aut-mei=Hirofumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=TetsunagaTomonori
en-aut-sei=Tetsunaga
en-aut-mei=Tomonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=MiyakeTakamasa
en-aut-sei=Miyake
en-aut-mei=Takamasa
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=YamadaKazuki
en-aut-sei=Yamada
en-aut-mei=Kazuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=AokiKiyoshi
en-aut-sei=Aoki
en-aut-mei=Kiyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=OzakiToshifumi
en-aut-sei=Ozaki
en-aut-mei=Toshifumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

affil-num=1
en-affil=Department of Orthopaedic Surgery, Okayama University Hospital
kn-affil=

affil-num=2
en-affil=Department of Orthopaedic Surgery, Okayama University Hospital
kn-affil=

affil-num=3
en-affil=Department of Orthopaedic Surgery, Kawasaki Medical School
kn-affil=

affil-num=4
en-affil=Department of Orthopaedic Surgery, Asahigawasou Rehabilitation and Medical Center
kn-affil=

affil-num=5
en-affil=Department of Orthopaedic Surgery, Okayama University Hospital
kn-affil=

affil-num=6
en-affil=Department of Orthopaedic Surgery, Okayama University Hospital
kn-affil=

affil-num=7
en-affil=Department of Orthopaedic Surgery, Okayama University Hospital
kn-affil=

affil-num=8
en-affil=Department of Orthopaedic Surgery, Asahigawasou Rehabilitation and Medical Center
kn-affil=

affil-num=9
en-affil=Department of Orthopaedic Surgery, Okayama University Hospital
kn-affil=
en-keyword=slipped capital femoral epiphyses
kn-keyword=slipped capital femoral epiphyses
en-keyword=intertrochanteric osteotomy
kn-keyword=intertrochanteric osteotomy
en-keyword=residual femoral deformity
kn-keyword=residual femoral deformity
en-keyword=femoroacetabular impingement
kn-keyword=femoroacetabular impingement
en-keyword=bone remodeling
kn-keyword=bone remodeling
END

start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=4
article-no=
start-page=279
end-page=289
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=201708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=An Analysis of the Characteristics and Improved Use of Newly Developed CT-based Navigation System in Total Hip Arthroplasty
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We developed a surface matching-type computed tomography (CT)-based navigation system for total hip arthroplasty (the N-navi; TEIJIN NAKASHIMA MEDICAL, Okayama, Japan). In the registration step, surface matching was performed with digitizing points on the pelvic bone surface after coarse paired matching. In the present study, we made model bones from the CT data of patients whose acetabular shapes had various deformities. We measured the distances and angles after surface matching from the fiducial points and evaluated the ability to correct surface-matching registration on each pelvic form, using several areas and numbers of points. When the surface-matching points were taken on the superior area of the acetabulum, the correction was easy for the external direction, but it was difficult to correct for the anterior and proximal directions. The correction was difficult for external and proximal directions on the posterior area. Each area of surface-matching points has particular directions that are easily corrected and other directions that are difficult to correct. The shape of the pelvis also affected the correction ability. Our present findings suggest that checking the position after coarse paired matching and choosing the surface-matching area and points that are optimal to correct will improve the accuracy of total hip arthroplasty and reduce surgical times.
en-copyright=
kn-copyright=

en-aut-name=FujiiYosuke
en-aut-sei=Fujii
en-aut-mei=Yosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=FujiwaraKazuo
en-aut-sei=Fujiwara
en-aut-mei=Kazuo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=TetsunagaTomonori
en-aut-sei=Tetsunaga
en-aut-mei=Tomonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=MiyakeTakamasa
en-aut-sei=Miyake
en-aut-mei=Takamasa
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=YamadaKazuki
en-aut-sei=Yamada
en-aut-mei=Kazuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=EndoHirosuke
en-aut-sei=Endo
en-aut-mei=Hirosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=AbeNobuhiro
en-aut-sei=Abe
en-aut-mei=Nobuhiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=SugitaNaohiko
en-aut-sei=Sugita
en-aut-mei=Naohiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=MitsuishiMamoru
en-aut-sei=Mitsuishi
en-aut-mei=Mamoru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=InoueTakayuki
en-aut-sei=Inoue
en-aut-mei=Takayuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=NakashimaYoshio
en-aut-sei=Nakashima
en-aut-mei=Yoshio
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=OzakiToshifumi
en-aut-sei=Ozaki
en-aut-mei=Toshifumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

affil-num=1
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=2
en-affil=Department of Intelligent Orthopaedic System Development, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=3
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=4
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=5
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=6
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=

affil-num=7
en-affil=Department of Orthopaedic Surgery, Kawasaki Medical school
kn-affil=

affil-num=8
en-affil=Department of Mechanical Engineering, School of Engineering, The University of Tokyo
kn-affil=

affil-num=9
en-affil=Department of Mechanical Engineering, School of Engineering, The University of Tokyo
kn-affil=

affil-num=10
en-affil=TEIJIN NAKASHIMA MEDICAL CO., LTD
kn-affil=

affil-num=11
en-affil=TEIJIN NAKASHIMA MEDICAL CO., LTD
kn-affil=

affil-num=12
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
en-keyword=total hip arthroplasty
kn-keyword=total hip arthroplasty
en-keyword=CT-based navigation system
kn-keyword=CT-based navigation system
en-keyword=surface matching
kn-keyword=surface matching
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=20170630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=人工股関節全置換術における新規開発ＣＴベースナビゲーションシステムの特徴と精度向上への検討
kn-title=An Analysis of the Characteristics and Improved Use of Newly Developed CT- based Navigation System in Total Hip Arthroplasty
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiYosuke
en-aut-sei=Fujii
en-aut-mei=Yosuke
kn-aut-name=藤井洋佑
kn-aut-sei=藤井
kn-aut-mei=洋佑
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=20170324
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=血管新生因子Angiogeninのリンパ管新生に果たす役割に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiYukiko
en-aut-sei=Fujii
en-aut-mei=Yukiko
kn-aut-name=藤井由紀子
kn-aut-sei=藤井
kn-aut-mei=由紀子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=2
article-no=
start-page=179
end-page=180
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=201704
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Intracranial Pressure Monitoring for Pediatric Acute Encephalopathy
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Newly published clinical practice guidelines recommend intracranial pressure (ICP) monitoring in critical care for the management of pediatric acute encephalopathy (pAE), but the utility of ICP monitoring for pAE has been poorly studied. We recently performed direct ICP monitoring for two patients. We observed that although the direct ICP monitoring had clinical benefits with less body weight gain and no vasopressor use in both cases, this monitoring technique is still invasive. Future studies should determine the utility of non-invasive ICP monitoring systems in pAE to further improve the quality of intensive-care management.
en-copyright=
kn-copyright=

en-aut-name=NosakaNobuyuki
en-aut-sei=Nosaka
en-aut-mei=Nobuyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=TsukaharaKohei
en-aut-sei=Tsukahara
en-aut-mei=Kohei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=KnaupEmily
en-aut-sei=Knaup
en-aut-mei=Emily
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=YabuuchiToshihiko
en-aut-sei=Yabuuchi
en-aut-mei=Toshihiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=KikkawaTomonobu
en-aut-sei=Kikkawa
en-aut-mei=Tomonobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=FujiiYosuke
en-aut-sei=Fujii
en-aut-mei=Yosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=YashiroMasato
en-aut-sei=Yashiro
en-aut-mei=Masato
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=YasuharaTakao
en-aut-sei=Yasuhara
en-aut-mei=Takao
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=OkadaAyumi
en-aut-sei=Okada
en-aut-mei=Ayumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=UgawaToyomu
en-aut-sei=Ugawa
en-aut-mei=Toyomu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=NakaoAtsunori
en-aut-sei=Nakao
en-aut-mei=Atsunori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=TsukaharaHirokazu
en-aut-sei=Tsukahara
en-aut-mei=Hirokazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=DateIsao
en-aut-sei=Date
en-aut-mei=Isao
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

affil-num=1
en-affil=Advanced Emergency and Critical Care Medical Center, Okayama University Hospital
kn-affil=

affil-num=2
en-affil=Advanced Emergency and Critical Care Medical Center, Okayama University Hospital
kn-affil=

affil-num=3
en-affil=Advanced Emergency and Critical Care Medical Center, Okayama University Hospital
kn-affil=

affil-num=4
en-affil=Department of Pediatrics, Okayama University Hospital
kn-affil=

affil-num=5
en-affil=Department of Pediatrics, Okayama University Hospital
kn-affil=

affil-num=6
en-affil=Department of Pediatrics, Okayama University Hospital
kn-affil=

affil-num=7
en-affil=Department of Pediatrics, Okayama University Hospital
kn-affil=

affil-num=8
en-affil=Department of Neurological Surgery, Okayama University Hospital
kn-affil=

affil-num=9
en-affil=Department of Pediatrics, Okayama University Hospital
kn-affil=

affil-num=10
en-affil=Advanced Emergency and Critical Care Center of Okayama University Hospital
kn-affil=

affil-num=11
en-affil=Advanced Emergency and Critical Care Medical Center, Okayama University Hospital
kn-affil=

affil-num=12
en-affil=Department of Pediatrics, Okayama University Hospital
kn-affil=

affil-num=13
en-affil=Department of Neurological Surgery, Okayama University Hospital
kn-affil=
en-keyword=cerebral perfusion
kn-keyword=cerebral perfusion
en-keyword=encephalopathy
kn-keyword=encephalopathy
en-keyword=child
kn-keyword=child
en-keyword=intracranial pressure
kn-keyword=intracranial pressure
en-keyword=neurological intensive care
kn-keyword=neurological intensive care
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2016
dt-pub=20161227
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=エラスターゼ誘導肺気腫モデルマウスにおけるIL-23の役割の検討
kn-title=IL-23 Is Essential for the Development of Elastase-Induced Pulmonary Inflammation and Emphysema
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiUtako
en-aut-sei=Fujii
en-aut-mei=Utako
kn-aut-name=藤井詩子
kn-aut-sei=藤井
kn-aut-mei=詩子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=48
cd-vols=
no-issue=2
article-no=
start-page=55
end-page=65
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2016
dt-pub=20161110
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An Interview Transcript on GaN Research History with Dr. Herbert Paul Maruska (2)
kn-title=インタビュー録 ： GaN系青色LED開発の先駆者Herbert Paul Maruska博士 （2）
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=128
cd-vols=
no-issue=3
article-no=
start-page=213
end-page=216
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2016
dt-pub=20161201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Probable IgG4-related thyroiditis with cervical lymphadenopathy
kn-title=リンパ節転移を伴う甲状腺癌を疑ったIgG4関連甲状腺炎（準確診群）の1 切除例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=　We present a case of probably IgG4-related thyroiditis with lymphadenopathy. The patient was a 70-year-old Japanese female who was undergoing hemodialysis and had undergone a right hemi-thyroidectomy in 1989 due to carcinoma. In December 2010, an ultrasonography study revealed a hypoechoic small lesion in thyroid gland. When the patient was admitted to our hospital in November 2013, the lesion and regional lymph nodes had enlarged and we suspected that they were metastatic thyroid cancer. We performed a residual total thyroidectomy and regional lymph node dissection in August 2014. At that time, lymphoplasmacytic infiltration and fibrosis were observed histopathologically in thyroid tissue. Immunohistochemical studies revealed infiltrated lymphocytes and plasma cells were markedly IgG-positive, and the ratio of IgG4-positive to IgG-positive cells was over 40%. We therefore diagnosed the patient with IgG4-related thyroiditis. The cervical lymph nodes were metastases of papillary carcinoma from 25 years earlier. The patient remains well without any recurrences 33 months after the surgery.
en-copyright=
kn-copyright=

en-aut-name=KobashiKenta
en-aut-sei=Kobashi
en-aut-mei=Kenta
kn-aut-name=小橋研太
kn-aut-sei=小橋
kn-aut-mei=研太
aut-affil-num=1
ORCID=

en-aut-name=IshiiHiroshi
en-aut-sei=Ishii
en-aut-mei=Hiroshi
kn-aut-name=石井博
kn-aut-sei=石井
kn-aut-mei=博
aut-affil-num=2
ORCID=

en-aut-name=NishiyamaKanako
en-aut-sei=Nishiyama
en-aut-mei=Kanako
kn-aut-name=西山加那子
kn-aut-sei=西山
kn-aut-mei=加那子
aut-affil-num=3
ORCID=

en-aut-name=MatsumiYuki
en-aut-sei=Matsumi
en-aut-mei=Yuki
kn-aut-name=松三雄騎
kn-aut-sei=松三
kn-aut-mei=雄騎
aut-affil-num=4
ORCID=

en-aut-name=HatanoMasahide
en-aut-sei=Hatano
en-aut-mei=Masahide
kn-aut-name=羽田野雅英
kn-aut-sei=羽田野
kn-aut-mei=雅英
aut-affil-num=5
ORCID=

en-aut-name=FujiwaraMasamitsu
en-aut-sei=Fujiwara
en-aut-mei=Masamitsu
kn-aut-name=藤原雅光
kn-aut-sei=藤原
kn-aut-mei=雅光
aut-affil-num=6
ORCID=

en-aut-name=KurokawaTatsuo
en-aut-sei=Kurokawa
en-aut-mei=Tatsuo
kn-aut-name=黒河達雄
kn-aut-sei=黒河
kn-aut-mei=達雄
aut-affil-num=7
ORCID=

en-aut-name=TsunemitsuKensuke
en-aut-sei=Tsunemitsu
en-aut-mei=Kensuke
kn-aut-name=常光謙輔
kn-aut-sei=常光
kn-aut-mei=謙輔
aut-affil-num=8
ORCID=

affil-num=1
en-affil=Department of Surgery, Saiseikai Saijo Hospital
kn-affil=済生会西条病院　外科

affil-num=2
en-affil=Department of Surgery, Saiseikai Saijo Hospital
kn-affil=済生会西条病院　外科

affil-num=3
en-affil=Breast Center, Ehime University Hospital
kn-affil=愛媛大学医学部附属病院　乳腺センター

affil-num=4
en-affil=Department of Surgery, Saiseikai Saijo Hospital
kn-affil=済生会西条病院　外科

affil-num=5
en-affil=Department of Surgery, Saiseikai Saijo Hospital
kn-affil=済生会西条病院　外科

affil-num=6
en-affil=Department of Surgery, Imabariishikaishimin Hospital
kn-affil=今治医師会市民病院　外科

affil-num=7
en-affil=Department of Surgery, Saiseikai Saijo Hospital
kn-affil=済生会西条病院　外科

affil-num=8
en-affil=Department of Surgery, Saiseikai Saijo Hospital
kn-affil=済生会西条病院　外科
en-keyword=IgG4 関連甲状腺炎（IgG4-related thyroiditis）
kn-keyword=IgG4 関連甲状腺炎（IgG4-related thyroiditis）
en-keyword=橋本病（Hashimoto’s thyroiditis）
kn-keyword=橋本病（Hashimoto’s thyroiditis）
en-keyword=転移性リンパ節腫瘍（metastatic lymph node tumor）
kn-keyword=転移性リンパ節腫瘍（metastatic lymph node tumor）
en-keyword=慢性腎不全（chronic renal failure）
kn-keyword=慢性腎不全（chronic renal failure）
END

start-ver=1.4
cd-journal=joma
no-vol=48
cd-vols=
no-issue=1
article-no=
start-page=61
end-page=77
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2016
dt-pub=20160715
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An Interview Transcript on GaN Research History with Dr. Herbert Paul Maruska (1)
kn-title=インタビュー録：GaN系青色LED開発の先駆者Herbert Paul Maruska博士（1）
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学社会文化科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=20151231
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=統合型HTP法の発達障害についての分析
kn-title=Analysis of the Synthetic-HTP drawing test about Developmental Disorders
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiChikako
en-aut-sei=Fujii
en-aut-mei=Chikako
kn-aut-name=藤井智香子
kn-aut-sei=藤井
kn-aut-mei=智香子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院
END

start-ver=1.4
cd-journal=joma
no-vol=127
cd-vols=
no-issue=3
article-no=
start-page=209
end-page=212
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=20151201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A primary diffuse large B-cell lymphoma of the liver treated with R-CHOP regimen
kn-title=Rituximab併用CHOP療法が奏効した肝原発びまん性大細胞型Ｂ細胞リンパ腫の１例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=　A 78-year-old Japanese man was referred to our hospital after experiencing black feces. No abnormal finding was detected in the endoscopic examination of his stomach and large intestines. Computed tomography (CT) of the abdomen revealed a tumor lesion in the right lobe of the liver. A needle biopsy of the tumor under ultrasound guidance was performed. A pathological examination of the biopsy specimen showed a diffuse proliferation of lymphoma cells, which was compatible with diffuse large B-cell lymphoma (DLBCL). F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)-CT demonstrated increased FDG uptake only in the liver tumor. We made the diagnosis of primary DLBCL of the liver. After six cycles of rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP), the patient achieved complete remission and has maintained remission for 2 years since the diagnosis. The R-CHOP regimen might be effective therapy for primary DLBCL of the liver.
en-copyright=
kn-copyright=

en-aut-name=OkadaHiroshi
en-aut-sei=Okada
en-aut-mei=Hiroshi
kn-aut-name=岡田博
kn-aut-sei=岡田
kn-aut-mei=博
aut-affil-num=1
ORCID=

en-aut-name=FujiiSoichiro
en-aut-sei=Fujii
en-aut-mei=Soichiro
kn-aut-name=藤井総一郎
kn-aut-sei=藤井
kn-aut-mei=総一郎
aut-affil-num=2
ORCID=

en-aut-name=WatanabeKentaro
en-aut-sei=Watanabe
en-aut-mei=Kentaro
kn-aut-name=渡邉謙太郎
kn-aut-sei=渡邉
kn-aut-mei=謙太郎
aut-affil-num=3
ORCID=

en-aut-name=ShigematuTerunobu
en-aut-sei=Shigematu
en-aut-mei=Terunobu
kn-aut-name=重松照伸
kn-aut-sei=重松
kn-aut-mei=照伸
aut-affil-num=4
ORCID=

en-aut-name=MiyashitaKatsuhiro
en-aut-sei=Miyashita
en-aut-mei=Katsuhiro
kn-aut-name=宮下雄博
kn-aut-sei=宮下
kn-aut-mei=雄博
aut-affil-num=5
ORCID=

en-aut-name=OkazakiMorihiro
en-aut-sei=Okazaki
en-aut-mei=Morihiro
kn-aut-name=岡崎守宏
kn-aut-sei=岡崎
kn-aut-mei=守宏
aut-affil-num=6
ORCID=

en-aut-name=KobashiHaruhiko
en-aut-sei=Kobashi
en-aut-mei=Haruhiko
kn-aut-name=小橋春彦
kn-aut-sei=小橋
kn-aut-mei=春彦
aut-affil-num=7
ORCID=

en-aut-name=YokoyamaMotohiro
en-aut-sei=Yokoyama
en-aut-mei=Motohiro
kn-aut-name=横山元浩
kn-aut-sei=横山
kn-aut-mei=元浩
aut-affil-num=8
ORCID=

en-aut-name=YoshinoTadashi
en-aut-sei=Yoshino
en-aut-mei=Tadashi
kn-aut-name=吉野正
kn-aut-sei=吉野
kn-aut-mei=正
aut-affil-num=9
ORCID=

affil-num=1
en-affil=
kn-affil=岡山赤十字病院

affil-num=2
en-affil=
kn-affil=岡山赤十字病院

affil-num=3
en-affil=
kn-affil=岡山赤十字病院

affil-num=4
en-affil=
kn-affil=岡山赤十字病院

affil-num=5
en-affil=
kn-affil=岡山赤十字病院

affil-num=6
en-affil=
kn-affil=岡山赤十字病院

affil-num=7
en-affil=
kn-affil=岡山赤十字病院

affil-num=8
en-affil=
kn-affil=岡山赤十字病院

affil-num=9
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科
en-keyword=びまん性大細胞型Ｂ細胞リンパ腫（diffuse large B-cell lymphoma）
kn-keyword=びまん性大細胞型Ｂ細胞リンパ腫（diffuse large B-cell lymphoma）
en-keyword=肝臓（liver）
kn-keyword=肝臓（liver）
en-keyword=R-CHOP療法（R-CHOP regimen）
kn-keyword=R-CHOP療法（R-CHOP regimen）
END

start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=5
article-no=
start-page=325
end-page=325
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=201510
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=For Vol.69, No.4, pp205-212 Venous Thromboembolism after Total Hip Arthroplasty Diagnosed by Enhanced Computed Tomography : Comparison of Selective Thromboprophylaxis and No Thromboprophylaxis
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Total hip arthroplasty (THA) is the most effective treatment for advanced or end-stage hip osteoarthritis. However, venous thromboembolism (VTE) remains one of its unresolved complications. We reviewed the records of 322 patients undergoing primary THA and investigated the efficacy of anticoagulant prophylaxis for VTE. Our study cohort consisted of 60 patients who received no anticoagulants, 100 patients who received a factor Xa inhibitor (fondaparinux), 100 patients who received low molecular weight heparin (enoxaparin), and 62 patients who selectively received no anticoagulant prophylaxis due to perioperative bleeding, weight, and/or hemoglobin concentration. Enhanced 64-slice multidetector row computed tomography was performed postoperatively for 7 days in all cases. The incidence of VTE in the four groups was 15%, 9.0%, 6.0%, and 6.4%, respectively. The incidence of VTE was significantly lower in the groups receiving anticoagulant prophylaxis and the group selectively receiving no anticoagulant prophylaxis than in the group receiving no anticoagulants. Complications of fondaparinux therapy included hepatic dysfunction in 4 cases (4.0%), minor bleeding in 2 cases (2.0%), persistent wound drainage in 3 cases (3.0%), and eruption in 1 case (1.0%). The complications of enoxaparin therapy were persistent wound drainage in 1 case (1.0%) and progression of anemia in 1 case (1.0%). The incidence of VTE was low in patients who selectively received no anticoagulant prophylaxis, so we conclude that anticoagulant prophylaxis should be used selectively in THA cases.
en-copyright=
kn-copyright=

en-aut-name=OkadaYoshiki
en-aut-sei=Okada
en-aut-mei=Yoshiki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=EndoHirosuke
en-aut-sei=Endo
en-aut-mei=Hirosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=MitaniShigeru
en-aut-sei=Mitani
en-aut-mei=Shigeru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=FujiwaraKazuo
en-aut-sei=Fujiwara
en-aut-mei=Kazuo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=TetsunagaTomonori
en-aut-sei=Tetsunaga
en-aut-mei=Tomonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=KagawaYohei
en-aut-sei=Kagawa
en-aut-mei=Yohei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=FujiiYosuke
en-aut-sei=Fujii
en-aut-mei=Yosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=KunisadaToshiyuki
en-aut-sei=Kunisada
en-aut-mei=Toshiyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=OzakiToshifumi
en-aut-sei=Ozaki
en-aut-mei=Toshifumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Orthopaedic Surgery, Takasago Municipal Hospital

affil-num=2
en-affil=
kn-affil=Department of Medical Materials for Musculoskeletal Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=3
en-affil=
kn-affil=Department of Orthopaedic Surgery, Kawasaki Medical School

affil-num=4
en-affil=
kn-affil=Intelligent Orthopaedic Systems, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=5
en-affil=
kn-affil=Department of Orthopaedic Surgery, Okayama University Hospital

affil-num=6
en-affil=
kn-affil=Department of Orthopaedic Surgery, Okayama University Hospital

affil-num=7
en-affil=
kn-affil=Department of Orthopaedic Surgery, Okayama University Hospital

affil-num=8
en-affil=
kn-affil=Department of Orthopaedic Surgery, Okayama University Hospital

affil-num=9
en-affil=
kn-affil=Department of Orthopaedic Surgery, Okayama University Hospital
en-keyword=total hip arthroplasty
kn-keyword=total hip arthroplasty
en-keyword=venous thromboembolism
kn-keyword=venous thromboembolism
en-keyword=anticoagulant prophylaxis
kn-keyword=anticoagulant prophylaxis
en-keyword=complications
kn-keyword=complications
END

start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=5
article-no=
start-page=301
end-page=306
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=201510
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Primary Duodenal Follicular Lymphoma Treated With Rituximab Monotherapy and Followed-up for 15 Years
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 41-year-old woman was diagnosed with duodenal follicular lymphoma. She had no other lesions and was assigned to a "watch and wait" policy. Swelling of the inguinal lymph nodes appeared 45 months later, and rituximab monotherapy resulted in complete remission. However, follicular lymphoma recurred in the stomach, rectum and mesenteric and external iliac lymph nodes 81 months after the therapy. The patient received rituximab monotherapy again and has remained in complete remission in the fifteenth year after the initial diagnosis. This case suggests the usefulness of rituximab monotherapy in the long-term management of intestinal follicular lymphoma.
en-copyright=
kn-copyright=

en-aut-name=SekiAnna
en-aut-sei=Seki
en-aut-mei=Anna
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=IwamuroMasaya
en-aut-sei=Iwamuro
en-aut-mei=Masaya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=YoshiokaMasao
en-aut-sei=Yoshioka
en-aut-mei=Masao
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=OkadaHiroyuki
en-aut-sei=Okada
en-aut-mei=Hiroyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=NoseSoichiro
en-aut-sei=Nose
en-aut-mei=Soichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=TakataKatsuyoshi
en-aut-sei=Takata
en-aut-mei=Katsuyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=YoshinoTadashi
en-aut-sei=Yoshino
en-aut-mei=Tadashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=YamamotoKazuhide
en-aut-sei=Yamamoto
en-aut-mei=Kazuhide
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Internal Medicine, Okayama Saiseikai General Hospital

affil-num=2
en-affil=
kn-affil=Department of Molecular Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=3
en-affil=
kn-affil=Department of Internal Medicine, Okayama Saiseikai General Hospital

affil-num=4
en-affil=
kn-affil=Department of Hematology and Oncology, Okayama University Hospital

affil-num=5
en-affil=
kn-affil=Department of Endoscopy, Okayama University Hospital

affil-num=6
en-affil=
kn-affil=Department of Anatomic Pathology, Okayama Saiseikai General Hospital

affil-num=7
en-affil=
kn-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=8
en-affil=
kn-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=9
en-affil=
kn-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
en-keyword=follicular lymphoma
kn-keyword=follicular lymphoma
en-keyword=duodenum
kn-keyword=duodenum
en-keyword=rituximab
kn-keyword=rituximab
END

start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=5
article-no=
start-page=279
end-page=290
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=201510
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Inhibitory Effects of Edaravone, a Free Radical Scavenger, on Cytokine-induced Hyperpermeability of Human Pulmonary Microvascular Endothelial Cells:A Comparison with Dexamethasone and Nitric Oxide Synthase Inhibitor
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Lung hyperpermeability affects the development of acute respiratory distress syndrome (ARDS), but therapeutic strategies for the control of microvascular permeability have not been established. We examined the effects of edaravone, dexamethasone, and N-monomethyl-L-arginine (L-NMMA) on permeability changes in human pulmonary microvascular endothelial cells (PMVEC) under a hypercytokinemic state. Human PMVEC were seeded in a Boyden chamber. After monolayer confluence was achieved, the culture media were replaced respectively by culture media containing edaravone, dexamethasone, and L-NMMA. After 24-h incubation, the monolayer was stimulated with tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). Fluorescein-labeled dextran was added. Then the trans-human PMVEC leak was measured. Expressions of vascular endothelial-cadherin (VE-cadherin) and zonula occludens-1 protein (ZO-1) were evaluated using real-time quantitative polymerase chain reaction and immunofluorescence microscopy. The results showed that TNF-α＋IL-1β markedly increased pulmonary microvascular permeability. Pretreatment with edaravone, dexamethasone, or L-NMMA attenuated the hyperpermeability and inhibited the cytokine-induced reduction of VE-cadherin expression on immunofluorescence staining. Edaravone and dexamethasone increased the expression of ZO-1 at both the mRNA and protein levels. Edaravone and dexamethasone inhibited the permeability changes of human PMVEC, at least partly through an enhancement of VE-cadherin. Collectively, these results suggest a potential therapeutic approach for intervention in patients with ARDS.
en-copyright=
kn-copyright=

en-aut-name=SaitoYukie
en-aut-sei=Saito
en-aut-mei=Yukie
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=FujiiYousuke
en-aut-sei=Fujii
en-aut-mei=Yousuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=YashiroMasato
en-aut-sei=Yashiro
en-aut-mei=Masato
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=TsugeMitsuru
en-aut-sei=Tsuge
en-aut-mei=Mitsuru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=NosakaNobuyuki
en-aut-sei=Nosaka
en-aut-mei=Nobuyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=YamashitaNobuko
en-aut-sei=Yamashita
en-aut-mei=Nobuko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=YamadaMutsuko
en-aut-sei=Yamada
en-aut-mei=Mutsuko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=TsukaharaHirokazu
en-aut-sei=Tsukahara
en-aut-mei=Hirokazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=MorishimaTsuneo
en-aut-sei=Morishima
en-aut-mei=Tsuneo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=2
en-affil=
kn-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=3
en-affil=
kn-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=4
en-affil=
kn-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=5
en-affil=
kn-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=6
en-affil=
kn-affil=Department of Virology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=7
en-affil=
kn-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=8
en-affil=
kn-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=9
en-affil=
kn-affil=Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
en-keyword=pulmonary microvascular endothelial cells
kn-keyword=pulmonary microvascular endothelial cells
en-keyword=permeability
kn-keyword=permeability
en-keyword=edaravone
kn-keyword=edaravone
en-keyword=vascular endothelial-cadherin
kn-keyword=vascular endothelial-cadherin
en-keyword=zonula occludens-1 protein
kn-keyword=zonula occludens-1 protein
END

start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=4
article-no=
start-page=205
end-page=212
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=201508
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Venous Thromboembolism after Total Hip Arthroplasty Diagnosed by Enhanced Computed Tomography : Comparison of Selective Thromboprophylaxis and No Thromboprophylaxis
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Total hip arthroplasty (THA) is the most effective treatment for advanced or end-stage hip osteoarthritis. However, venous thromboembolism (VTE) remains one of its unresolved complications. We reviewed the records of 322 patients undergoing primary THA and investigated the efficacy of anticoagulant prophylaxis for VTE. Our study cohort consisted of 60 patients who received no anticoagulants, 100 patients who received a factor Xa inhibitor (fondaparinux), 100 patients who received low molecular weight heparin (enoxaparin), and 62 patients who selectively received no anticoagulant prophylaxis due to perioperative bleeding, weight, and/or hemoglobin concentration. Enhanced 64-slice multidetector row computed tomography was performed postoperatively for 7 days in all cases. The incidence of VTE in the four groups was 15ｵ, 9.0ｵ, 6.0ｵ, and 6.4ｵ, respectively. The incidence of VTE was significantly lower in the groups receiving anticoagulant prophylaxis and the group selectively receiving no anticoagulant prophylaxis than in the group receiving no anticoagulants. Complications of fondaparinux therapy included hepatic dysfunction in 4 cases (4.0ｵ), minor bleeding in 2 cases (2.0ｵ), persistent wound drainage in 3 cases (3.0ｵ), and eruption in 1 case (1.0ｵ). The complications of enoxaparin therapy were persistent wound drainage in 1 case (1.0ｵ) and progression of anemia in 1 case (1.0ｵ). The incidence of VTE was low in patients who selectively received no anticoagulant prophylaxis, so we conclude that anticoagulant prophylaxis should be used selectively in THA cases.
en-copyright=
kn-copyright=

en-aut-name=OkadaYoshiki
en-aut-sei=Okada
en-aut-mei=Yoshiki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=EndoHirosuke
en-aut-sei=Endo
en-aut-mei=Hirosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=MitaniShigeru
en-aut-sei=Mitani
en-aut-mei=Shigeru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=FujiwaraKazuo
en-aut-sei=Fujiwara
en-aut-mei=Kazuo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=TetsunagaTomonori
en-aut-sei=Tetsunaga
en-aut-mei=Tomonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=KagawaYohei
en-aut-sei=Kagawa
en-aut-mei=Yohei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=FujiiYosuke
en-aut-sei=Fujii
en-aut-mei=Yosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=KunisadaToshiyuki
en-aut-sei=Kunisada
en-aut-mei=Toshiyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=OzakiToshifumi
en-aut-sei=Ozaki
en-aut-mei=Toshifumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Orthopaedic Surgery, Takasago Municipal Hospital

affil-num=2
en-affil=
kn-affil=Department of Medical Materials for Musculoskeletal Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=3
en-affil=
kn-affil=Department of Orthopaedic Surgery, Kawasaki Medical School

affil-num=4
en-affil=
kn-affil=Intelligent Orthopaedic Systems, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=5
en-affil=
kn-affil=Department of Orthopaedic Surgery, Okayama University Hospital

affil-num=6
en-affil=
kn-affil=Department of Orthopaedic Surgery, Okayama University Hospital

affil-num=7
en-affil=
kn-affil=Department of Orthopaedic Surgery, Okayama University Hospital

affil-num=8
en-affil=
kn-affil=Department of Orthopaedic Surgery, Okayama University Hospital

affil-num=9
en-affil=
kn-affil=Department of Orthopaedic Surgery, Okayama University Hospital
en-keyword=total hip arthroplasty
kn-keyword=total hip arthroplasty
en-keyword=venous thromboembolism
kn-keyword=venous thromboembolism
en-keyword=anticoagulant prophylaxis
kn-keyword=anticoagulant prophylaxis
en-keyword=complications
kn-keyword=complications
END

start-ver=1.4
cd-journal=joma
no-vol=47
cd-vols=
no-issue=1
article-no=
start-page=15
end-page=30
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=20150702
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Entrepreneurial Initiatives to the Paradigm Shift towards Sound Material Cycle Economy: A Case Study of Japanese Plastic Food Container Industry
kn-title=資源循環型経済へのパラダイム転換試論： プラスチック製食品用トレーの事例分析
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=127
cd-vols=
no-issue=2
article-no=
start-page=117
end-page=121
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=20150803
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Successful laparoscopic resection of a cecal tumor in a 95-year-old man
kn-title=超高齢者（95歳）の進行盲腸癌に対して腹腔鏡下回盲部切除を施行した1例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We report a successful laparoscopic resection of a cecal tumor in a 95-year-old Japanese man. The patient visited an initial hospital with a complaint of constipation in March 2014. Computed tomography scan and colonoscopy showed a stenotic ileocecal cancer with pericolic lymph node metastases, and he was referred to our department for management. Since his general condition was maintained, we performed a laparoscopic ileocecal resection with regional lymph node dissection for the patient. The operation achieved curative resection, and the tumor was diagnosed as a moderately differentiated adenocarcinoma and graded as pStage IIIa (pT3, pN0, pM0) according to the Japanese Classification of Colorectal Carcinoma, eighth edition. He was discharged on the 11th postoperative day without perioperative complications. Several large-scale randomized controlled trials （RCTs） revealed that laparoscopic surgeries for colorectal cancers have some advantages compared to open surgeries, including superior short-term outcomes and comparable long-term outcomes. Unfortunately, since these RCTs did not include enough elderly patients, the safety and feasibility of laparoscopic surgery for extremely elderly patients are still unknown. With respect to less-invasive procedures, these advantages of laparoscopic surgery are also thought to be the advantages for elderly colorectal cancer patients.
en-copyright=
kn-copyright=

en-aut-name=WatanabeAyako
en-aut-sei=Watanabe
en-aut-mei=Ayako
kn-aut-name=渡邉彩子
kn-aut-sei=渡邉
kn-aut-mei=彩子
aut-affil-num=1
ORCID=

en-aut-name=InadaRyo
en-aut-sei=Inada
en-aut-mei=Ryo
kn-aut-name=稲田涼
kn-aut-sei=稲田
kn-aut-mei=涼
aut-affil-num=2
ORCID=

en-aut-name=NagasakaTakeshi
en-aut-sei=Nagasaka
en-aut-mei=Takeshi
kn-aut-name=永坂岳司
kn-aut-sei=永坂
kn-aut-mei=岳司
aut-affil-num=3
ORCID=

en-aut-name=YagiTomohiko
en-aut-sei=Yagi
en-aut-mei=Tomohiko
kn-aut-name=八木朝彦
kn-aut-sei=八木
kn-aut-mei=朝彦
aut-affil-num=4
ORCID=

en-aut-name=MatsumotoHijiri
en-aut-sei=Matsumoto
en-aut-mei=Hijiri
kn-aut-name=松本聖
kn-aut-sei=松本
kn-aut-mei=聖
aut-affil-num=5
ORCID=

en-aut-name=ToshimaToshiaki
en-aut-sei=Toshima
en-aut-mei=Toshiaki
kn-aut-name=戸嶋俊明
kn-aut-sei=戸嶋
kn-aut-mei=俊明
aut-affil-num=6
ORCID=

en-aut-name=KikuchiSatoru
en-aut-sei=Kikuchi
en-aut-mei=Satoru
kn-aut-name=菊池覚次
kn-aut-sei=菊池
kn-aut-mei=覚次
aut-affil-num=7
ORCID=

en-aut-name=KurodaShinshi
en-aut-sei=Kuroda
en-aut-mei=Shinshi
kn-aut-name=黒田新士
kn-aut-sei=黒田
kn-aut-mei=新士
aut-affil-num=8
ORCID=

en-aut-name=KondoYoshitaka
en-aut-sei=Kondo
en-aut-mei=Yoshitaka
kn-aut-name=近藤喜太
kn-aut-sei=近藤
kn-aut-mei=喜太
aut-affil-num=9
ORCID=

en-aut-name=MoriYoshiko
en-aut-sei=Mori
en-aut-mei=Yoshiko
kn-aut-name=母里淑子
kn-aut-sei=母里
kn-aut-mei=淑子
aut-affil-num=10
ORCID=

en-aut-name=KishimotoHiroyuki
en-aut-sei=Kishimoto
en-aut-mei=Hiroyuki
kn-aut-name=岸本浩行
kn-aut-sei=岸本
kn-aut-mei=浩行
aut-affil-num=11
ORCID=

en-aut-name=FujiwaraToshiyoshi
en-aut-sei=Fujiwara
en-aut-mei=Toshiyoshi
kn-aut-name=藤原俊義
kn-aut-sei=藤原
kn-aut-mei=俊義
aut-affil-num=12
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科

affil-num=2
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科

affil-num=3
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科

affil-num=4
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科

affil-num=5
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科

affil-num=6
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科

affil-num=7
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科

affil-num=8
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科

affil-num=9
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科

affil-num=10
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科

affil-num=11
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科

affil-num=12
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科
en-keyword=超高齢者（extremely elderly patient）
kn-keyword=超高齢者（extremely elderly patient）
en-keyword=大腸癌（colorectal cancer）
kn-keyword=大腸癌（colorectal cancer）
en-keyword=腹腔鏡手術（laparoscopic surgery）
kn-keyword=腹腔鏡手術（laparoscopic surgery）
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=20150325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=半月板inner領域におけるChondromodulin-Iの血管内皮細胞増殖抑制効果
kn-title=Chondromodulin-I Derived from the Inner Meniscus Prevents Endothelial Cell Proliferation
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiMasataka
en-aut-sei=Fujii
en-aut-mei=Masataka
kn-aut-name=藤井政孝
kn-aut-sei=藤井
kn-aut-mei=政孝
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院
END

start-ver=1.4
cd-journal=joma
no-vol=127
cd-vols=
no-issue=1
article-no=
start-page=67
end-page=68
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=20150401
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=藤井病院
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=宮阪英
kn-aut-sei=宮阪
kn-aut-mei=英
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=5
cd-vols=
no-issue=
article-no=
start-page=139
end-page=148
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=20150306
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Organized and Sustainable Education Program for Drug Abuse Prevention by Yogo-teachers
kn-title=養護教諭が推進する組織的で継続可能な小学校の喫煙・飲酒・薬物乱用防止教育プログラムの開発と実践
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=　学校における喫煙・飲酒・薬物乱用防止教育の充実には，問題行動が顕在化する中学校期だけでなく小学校期
における指導の推進が重要であり，系統的な指導計画を立て，指導者や時間の確保，教材作成などに組織的に取
組み，継続可能なプログラム開発を行う必要がある。そこで，地区内12 校の養護教諭が協働して，発達段階に応
じた系統的・組織的かつ継続可能な地区共通の指導計画を開発し，各校の教育課程・年間計画に位置付けた実践
研究を行った。その結果，指導計画の実施状況は，小学校11 校中，学級活動10 校，ミニ保健指導10 校，長期
休業前指導6 校，広報活動9 校となり，特別支援学校1 校では広報活動のみを行うことができた。小学校におけ
る喫煙・飲酒・薬物乱用防止教育の推進には，学校保健活動の中核的役割を担う養護教諭が専門性を活かし協働
して，系統的な指導計画を各校の教育課程に位置付け組織的で継続可能なプログラムとする取組が有効であった。
en-copyright=
kn-copyright=

en-aut-name=UenoYoshiko
en-aut-sei=Ueno
en-aut-mei=Yoshiko
kn-aut-name=上野芳子
kn-aut-sei=上野
kn-aut-mei=芳子
aut-affil-num=1
ORCID=

en-aut-name=NishimuraTakae
en-aut-sei=Nishimura
en-aut-mei=Takae
kn-aut-name=西村孝江
kn-aut-sei=西村
kn-aut-mei=孝江
aut-affil-num=2
ORCID=

en-aut-name=HosakaSayuri
en-aut-sei=Hosaka
en-aut-mei=Sayuri
kn-aut-name=保坂小百合
kn-aut-sei=保坂
kn-aut-mei=小百合
aut-affil-num=3
ORCID=

en-aut-name=YamamotoMasae
en-aut-sei=Yamamoto
en-aut-mei=Masae
kn-aut-name=山本雅恵
kn-aut-sei=山本
kn-aut-mei=雅恵
aut-affil-num=4
ORCID=

en-aut-name=AkasakaRie
en-aut-sei=Akasaka
en-aut-mei=Rie
kn-aut-name=赤坂理恵
kn-aut-sei=赤坂
kn-aut-mei=理恵
aut-affil-num=5
ORCID=

en-aut-name=ArimatuAyumi
en-aut-sei=Arimatu
en-aut-mei=Ayumi
kn-aut-name=有松亜由美
kn-aut-sei=有松
kn-aut-mei=亜由美
aut-affil-num=6
ORCID=

en-aut-name=FujiiHarue
en-aut-sei=Fujii
en-aut-mei=Harue
kn-aut-name=藤井治江
kn-aut-sei=藤井
kn-aut-mei=治江
aut-affil-num=7
ORCID=

en-aut-name=YuguchiMakoto
en-aut-sei=Yuguchi
en-aut-mei=Makoto
kn-aut-name=湯口真琴
kn-aut-sei=湯口
kn-aut-mei=真琴
aut-affil-num=8
ORCID=

en-aut-name=TorigoeKanako
en-aut-sei=Torigoe
en-aut-mei=Kanako
kn-aut-name=鳥越加奈子
kn-aut-sei=鳥越
kn-aut-mei=加奈子
aut-affil-num=9
ORCID=

en-aut-name=OonishiMarika
en-aut-sei=Oonishi
en-aut-mei=Marika
kn-aut-name=大西真莉香
kn-aut-sei=大西
kn-aut-mei=真莉香
aut-affil-num=10
ORCID=

en-aut-name=NanbaYumiko
en-aut-sei=Nanba
en-aut-mei=Yumiko
kn-aut-name=難波有美子
kn-aut-sei=難波
kn-aut-mei=有美子
aut-affil-num=11
ORCID=

en-aut-name=MoriAyako
en-aut-sei=Mori
en-aut-mei=Ayako
kn-aut-name=森文子
kn-aut-sei=森
kn-aut-mei=文子
aut-affil-num=12
ORCID=

en-aut-name=WashidaHiroe
en-aut-sei=Washida
en-aut-mei=Hiroe
kn-aut-name=鷲田洋恵
kn-aut-sei=鷲田
kn-aut-mei=洋恵
aut-affil-num=13
ORCID=

en-aut-name=NishimotoKeiko
en-aut-sei=Nishimoto
en-aut-mei=Keiko
kn-aut-name=西本圭子
kn-aut-sei=西本
kn-aut-mei=圭子
aut-affil-num=14
ORCID=

en-aut-name=HinoYuko
en-aut-sei=Hino
en-aut-mei=Yuko
kn-aut-name=日野裕子
kn-aut-sei=日野
kn-aut-mei=裕子
aut-affil-num=15
ORCID=

en-aut-name=MatumotoTomoko
en-aut-sei=Matumoto
en-aut-mei=Tomoko
kn-aut-name=松本智子
kn-aut-sei=松本
kn-aut-mei=智子
aut-affil-num=16
ORCID=

en-aut-name=IshiharaTomoko
en-aut-sei=Ishihara
en-aut-mei=Tomoko
kn-aut-name=石原智子
kn-aut-sei=石原
kn-aut-mei=智子
aut-affil-num=17
ORCID=

en-aut-name=TodoMariko
en-aut-sei=Todo
en-aut-mei=Mariko
kn-aut-name=藤堂真莉子
kn-aut-sei=藤堂
kn-aut-mei=真莉子
aut-affil-num=18
ORCID=

en-aut-name=YamamotoKumiko
en-aut-sei=Yamamoto
en-aut-mei=Kumiko
kn-aut-name=山本久美子
kn-aut-sei=山本
kn-aut-mei=久美子
aut-affil-num=19
ORCID=

en-aut-name=SadamoriNatuki
en-aut-sei=Sadamori
en-aut-mei=Natuki
kn-aut-name=定森奈月
kn-aut-sei=定森
kn-aut-mei=奈月
aut-affil-num=20
ORCID=

en-aut-name=YamagamiNao
en-aut-sei=Yamagami
en-aut-mei=Nao
kn-aut-name=山上奈緒
kn-aut-sei=山上
kn-aut-mei=奈緒
aut-affil-num=21
ORCID=

en-aut-name=OkamotoKanako
en-aut-sei=Okamoto
en-aut-mei=Kanako
kn-aut-name=岡本佳菜子
kn-aut-sei=岡本
kn-aut-mei=佳菜子
aut-affil-num=22
ORCID=

en-aut-name=MatsuoHiromi
en-aut-sei=Matsuo
en-aut-mei=Hiromi
kn-aut-name=松尾裕未
kn-aut-sei=松尾
kn-aut-mei=裕未
aut-affil-num=23
ORCID=

en-aut-name=KobayashiShizuka
en-aut-sei=Kobayashi
en-aut-mei=Shizuka
kn-aut-name=小林静香
kn-aut-sei=小林
kn-aut-mei=静香
aut-affil-num=24
ORCID=

en-aut-name=HayashiKanako
en-aut-sei=Hayashi
en-aut-mei=Kanako
kn-aut-name=林加奈子
kn-aut-sei=林
kn-aut-mei=加奈子
aut-affil-num=25
ORCID=

en-aut-name=MizushimaNozomi
en-aut-sei=Mizushima
en-aut-mei=Nozomi
kn-aut-name=水島希望
kn-aut-sei=水島
kn-aut-mei=希望
aut-affil-num=26
ORCID=

en-aut-name=SekiyamaKen-ichi
en-aut-sei=Sekiyama
en-aut-mei=Ken-ichi
kn-aut-name=関山賢一
kn-aut-sei=関山
kn-aut-mei=賢一
aut-affil-num=27
ORCID=

en-aut-name=FukushimaTakashi
en-aut-sei=Fukushima
en-aut-mei=Takashi
kn-aut-name=福嶋隆
kn-aut-sei=福嶋
kn-aut-mei=隆
aut-affil-num=28
ORCID=

en-aut-name=KamimuraHiroko
en-aut-sei=Kamimura
en-aut-mei=Hiroko
kn-aut-name=上村弘子
kn-aut-sei=上村
kn-aut-mei=弘子
aut-affil-num=29
ORCID=

en-aut-name=TakahashiKayo
en-aut-sei=Takahashi
en-aut-mei=Kayo
kn-aut-name=高橋香代
kn-aut-sei=高橋
kn-aut-mei=香代
aut-affil-num=30
ORCID=

affil-num=1
en-affil=
kn-affil=倉敷市立西阿知小学校

affil-num=2
en-affil=
kn-affil=倉敷市立粒江小学校

affil-num=3
en-affil=
kn-affil=倉敷市立連島北小学校

affil-num=4
en-affil=
kn-affil=倉敷市立老松小学校

affil-num=5
en-affil=
kn-affil=倉敷市立老松小学校

affil-num=6
en-affil=
kn-affil=倉敷市立老松小学校

affil-num=7
en-affil=
kn-affil=倉敷市立大高小学校

affil-num=8
en-affil=
kn-affil=倉敷市立大高小学校

affil-num=9
en-affil=
kn-affil=倉敷市立大高小学校

affil-num=10
en-affil=
kn-affil=倉敷市立中洲小学校

affil-num=11
en-affil=
kn-affil=倉敷市立中洲小学校

affil-num=12
en-affil=
kn-affil=倉敷市立天城小学校

affil-num=13
en-affil=
kn-affil=倉敷市立西阿知小学校

affil-num=14
en-affil=
kn-affil=倉敷市立西阿知小学校

affil-num=15
en-affil=
kn-affil=倉敷市立西阿知小学校

affil-num=16
en-affil=
kn-affil=倉敷市立倉敷南小学校

affil-num=17
en-affil=
kn-affil=倉敷市立中島小学校

affil-num=18
en-affil=
kn-affil=倉敷市立中島小学校

affil-num=19
en-affil=
kn-affil=倉敷市立葦高小学校

affil-num=20
en-affil=
kn-affil=倉敷市立葦高小学校

affil-num=21
en-affil=
kn-affil=倉敷市立旭丘小学校

affil-num=22
en-affil=
kn-affil=倉敷市立旭丘小学校

affil-num=23
en-affil=
kn-affil=倉敷市立倉敷支援学校

affil-num=24
en-affil=
kn-affil=倉敷市立倉敷支援学校

affil-num=25
en-affil=
kn-affil=倉敷市立倉敷支援学校

affil-num=26
en-affil=
kn-affil=倉敷市立倉敷支援学校

affil-num=27
en-affil=
kn-affil=倉敷市立葦高小学校

affil-num=28
en-affil=
kn-affil=倉敷市立老松小学校

affil-num=29
en-affil=
kn-affil=岡山大学大学院教育学研究科

affil-num=30
en-affil=
kn-affil=くらしき作陽大学こども教育学部
en-keyword=小学校
kn-keyword=小学校
en-keyword=健康教育
kn-keyword=健康教育
en-keyword=喫煙・飲酒・薬物乱用防止教育
kn-keyword=喫煙・飲酒・薬物乱用防止教育
en-keyword=養護教諭
kn-keyword=養護教諭
en-keyword=中核的役割
kn-keyword=中核的役割
END

start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=2
article-no=
start-page=233
end-page=253
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2014
dt-pub=20141218
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Public Supports to Disaster Restoration and Reconstruction Activities: A Report on Staff Dispatch by Social Welfare Councils from Okayama to Miyagi
kn-title=社会福祉協議会による災害復旧・復興支援活動：岡山県から宮城県への職員派遣の事例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=YoshidaAkira
en-aut-sei=Yoshida
en-aut-mei=Akira
kn-aut-name=吉田明
kn-aut-sei=吉田
kn-aut-mei=明
aut-affil-num=1
ORCID=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=126
cd-vols=
no-issue=3
article-no=
start-page=223
end-page=226
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2014
dt-pub=20141201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of microscopic low-grade appendiceal mucinous neoplasm complicated with appendicitis resected by reduced-port laparoscopic surgery
kn-title=Reduced Port Surgeryで切除した高度炎症を伴う虫垂中に発見された潜在性虫垂粘液嚢胞腺腫の１例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Appendicitis is a benign disease for which surgical treatment is widely provided. The complication of neoplastic lesions may be discovered only after resection. However, in some cases, specimens are not submitted to histopathological examination in Japan because of an extreme deficiency of pathologists. We report our experience with one patient who experienced the complication of latent low-grade appendiceal mucinous neoplasm (LAMN) after surgery for appendicitis.
 Our patient was an 85-year-old woman. Conservative treatment failed to relieve fever and lower abdominal pain and it was decided to treat her surgically. Abdominal computed tomography (CT) showed appendicitis with severe inflammation and suspected adhesion. We decided to explore the abdominal cavity using a reduced-port laparoscopic approach. We found no mucous debouchment or clear tumors in the specimen. Histopathological findings indicated the coexistence of appendicitis and LAMN. At one year and a half after surgery, there was no evidence of the development of pseudomyxoma peritonei.
 In appendectomy, it is thought that careful perioperative treatment and a postoperative pathological search are important when there are no preoperative findings suggesting a neoplastic lesion.
en-copyright=
kn-copyright=

en-aut-name=SuzukiHiromitsu
en-aut-sei=Suzuki
en-aut-mei=Hiromitsu
kn-aut-name=鈴木宏光
kn-aut-sei=鈴木
kn-aut-mei=宏光
aut-affil-num=1
ORCID=

en-aut-name=KimuraKouji
en-aut-sei=Kimura
en-aut-mei=Kouji
kn-aut-name=木村紘爾
kn-aut-sei=木村
kn-aut-mei=紘爾
aut-affil-num=2
ORCID=

en-aut-name=KinoshitaSigeki
en-aut-sei=Kinoshita
en-aut-mei=Sigeki
kn-aut-name=木下茂喜
kn-aut-sei=木下
kn-aut-mei=茂喜
aut-affil-num=3
ORCID=

en-aut-name=OkanoKazuo
en-aut-sei=Okano
en-aut-mei=Kazuo
kn-aut-name=岡野和雄
kn-aut-sei=岡野
kn-aut-mei=和雄
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=倉敷市立児島市民病院　外科

affil-num=2
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　呼吸器・乳腺内分泌外科学

affil-num=3
en-affil=
kn-affil=倉敷市立児島市民病院　外科

affil-num=4
en-affil=
kn-affil=倉敷市立児島市民病院　外科
en-keyword=虫垂炎（appendicitis）
kn-keyword=虫垂炎（appendicitis）
en-keyword=減孔式腹腔鏡手術（reduced-port laparoscopic surgery）
kn-keyword=減孔式腹腔鏡手術（reduced-port laparoscopic surgery）
en-keyword=虫垂粘液嚢胞腺腫（low-grade appendiceal mucinous neoplasm (LAMN)）
kn-keyword=虫垂粘液嚢胞腺腫（low-grade appendiceal mucinous neoplasm (LAMN)）
en-keyword=腹膜偽粘液腫（pseudomyxoma peritonei）
kn-keyword=腹膜偽粘液腫（pseudomyxoma peritonei）
en-keyword=腹腔鏡下虫垂切除術（laparoscopic appendectomy）
kn-keyword=腹腔鏡下虫垂切除術（laparoscopic appendectomy）
END

start-ver=1.4
cd-journal=joma
no-vol=45
cd-vols=
no-issue=7
article-no=
start-page=1379
end-page=1387
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2014
dt-pub=201407
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Low-grade B-cell lymphoma presenting primarily in the bone marrow
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Cases of low-grade B-cell lymphoma presenting primarily in the bone marrow are rare, and its clinicopathology remains unclear. We retrospectively examined patients with low-grade B-cell lymphoma presenting primarily in the bone marrow. Fourteen patients met the inclusion criteria, including 5 with lymphoplasmacytic lymphoma (LPL), 3 with chronic lymphocytic leukemia/small lymphocytic lymphoma, 2 with follicular lymphoma (FL), and 4 with low-grade B-cell lymphoma not otherwise specified (LGBCL-NOS). The median age was 69.5 years (range, 42-89 years), and a slight male predominance was noted (9 men and 5 women, 1.8: 1). Immunohistochemically, all cases were positive for CD20. One case was positive for CD138. Both cases of FL were positive for CD10 and B-cell lymphoma 2 (BCL-2), and immunoglobulin heavy locus (IgH)/B-cell lymphoma 2 rearrangement was observed by fluorescence in situ hybridization. The myeloid differentiation primary response gene (88) leucine to proline mutation was observed in 3 of 5 LPL, 1 of 2 FL, and 2 of 4 LGBCL-NOS patients. Paraproteinemia was observed in 10 patients; IgM and IgG paraproteinemia were observed in 6 and 3 patients, respectively. In this patient series, 3 patients had died at a median follow-up of 36.5 months; the cause of death of 1 LPL patient was malignant lymphoma itself. Thus, low-grade B-cell lymphoma presenting primarily in the bone marrow has various subtypes, and approximately one-third of the patients had LGBCL-NOS. The immunophenotypic features and myeloid differentiation primary response gene (88) leucine to proline mutation data of LGBCL-NOS suggested that some cases present with characteristics similar to those of LPL or marginal zone lymphoma.
en-copyright=
kn-copyright=

en-aut-name=IwataniKayoko
en-aut-sei=Iwatani
en-aut-mei=Kayoko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=TakataKatsuyoshi
en-aut-sei=Takata
en-aut-mei=Katsuyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=SatoYasuharu
en-aut-sei=Sato
en-aut-mei=Yasuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=Miyata-TakataTomoko
en-aut-sei=Miyata-Takata
en-aut-mei=Tomoko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=IwakiNoriko
en-aut-sei=Iwaki
en-aut-mei=Noriko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=CuiWei
en-aut-sei=Cui
en-aut-mei=Wei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=Sawada-KitamuraSeiko
en-aut-sei=Sawada-Kitamura
en-aut-mei=Seiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=SonobeHiroshi
en-aut-sei=Sonobe
en-aut-mei=Hiroshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=TamuraMaiko
en-aut-sei=Tamura
en-aut-mei=Maiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=SaitoKatsuhiko
en-aut-sei=Saito
en-aut-mei=Katsuhiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=MiyataniKatsuya
en-aut-sei=Miyatani
en-aut-mei=Katsuya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=YamasakiRie
en-aut-sei=Yamasaki
en-aut-mei=Rie
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=YamadoriIchiro
en-aut-sei=Yamadori
en-aut-mei=Ichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=

en-aut-name=TerasakiYasushi
en-aut-sei=Terasaki
en-aut-mei=Yasushi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=16
ORCID=

en-aut-name=TanimotoMitsune
en-aut-sei=Tanimoto
en-aut-mei=Mitsune
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=17
ORCID=

en-aut-name=NakamuraNaoya
en-aut-sei=Nakamura
en-aut-mei=Naoya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=18
ORCID=

en-aut-name=YoshinoTadashi
en-aut-sei=Yoshino
en-aut-mei=Tadashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=19
ORCID=

affil-num=1
en-affil=
kn-affil=Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol

affil-num=2
en-affil=
kn-affil=Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol

affil-num=3
en-affil=
kn-affil=Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol

affil-num=4
en-affil=
kn-affil=Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol

affil-num=5
en-affil=
kn-affil=Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol

affil-num=6
en-affil=
kn-affil=Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol

affil-num=7
en-affil=
kn-affil=Kanazawa Univ Hosp, Div Pathol

affil-num=8
en-affil=
kn-affil=Chugoku Cent Hosp, Div Pathol

affil-num=9
en-affil=
kn-affil=Hiroshima City Hosp, Div Pathol

affil-num=10
en-affil=
kn-affil=Toyama City Hosp, Dept Pathol

affil-num=11
en-affil=
kn-affil=Mitoyo Gen Hosp, Div Pathol

affil-num=12
en-affil=
kn-affil=Natl Hosp Org Iwakuni, Ctr Clin, Div Pathol

affil-num=13
en-affil=
kn-affil=Natl Hosp Org Okayama, Med Ctr, Div Pathol

affil-num=14
en-affil=
kn-affil=Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Hematol & Oncol

affil-num=15
en-affil=
kn-affil=Toyama City Hosp, Div Hematol

affil-num=16
en-affil=
kn-affil=Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Hematol & Oncol

affil-num=17
en-affil=
kn-affil=Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Hematol & Oncol

affil-num=18
en-affil=
kn-affil=Tokai Univ, Inst Med Sci, Dept Pathol

affil-num=19
en-affil=
kn-affil=Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol
en-keyword=Low-grade B cell lymphoma
kn-keyword=Low-grade B cell lymphoma
en-keyword=Bone marrow
kn-keyword=Bone marrow
en-keyword=LGBCL-NOS
kn-keyword=LGBCL-NOS
en-keyword=MYD88
kn-keyword=MYD88
END

start-ver=1.4
cd-journal=joma
no-vol=20
cd-vols=
no-issue=2
article-no=
start-page=183
end-page=191
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2014
dt-pub=201402
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Mammalian Target of Rapamycin Inhibitors Permit Regulatory T Cell Reconstitution and Inhibit Experimental Chronic Graft-versus-Host Disease
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Chronic graft-versus-host disease (GVHD) remains a major late complication of allogeneic bone marrow transplantation (BMT). In a previous study, impaired thymic negative selection of the recipients permitted the emergence of pathogenic T cells that cause chronic GVHD using MHC class II-deficient (H2-Ab1 KO) B6 into OH model and CD4(+) T cells isolated from chronic GVHD mice caused chronic GVHD when administered into the secondary recipients. In this study, we evaluated the kinetics of regulatory T cell (Treg) reconstitution in wild type B6 into C3H model. After myeloablative conditioning, host Tregs disappeared rapidly, followed by expansion of Tregs derived from the donor splenic T cell inoculum. However, the donor splenic T cell derived Treg pool contracted gradually and was almost completely replaced by newly generated donor bone marrow (BM)-derived Tregs in the late post-transplantation period. Next, we compared the effects of cyclosporine (CSA) and mammalian target of rapamycin (mTOR) inhibitors on Treg reconstitution. Administration of CSA significantly impaired Treg reconstitution in the spleen and thymus. In contrast, BM-derived Treg reconstitution was not impaired in mTOR inhibitor-treated mice. Histopathological examination indicated that mice treated with GSA, but not mTOR inhibitors, showed pathogenic features of chronic GVHD on day 120. Mice treated with CSA until day 60, but not mTOR inhibitors, developed severe chronic GVHD followed by adoptive transfer of the pathogenic CD4(+) T cells isolated from H2-Ab1 KO into C3H model. These findings indicated that long-term use of CSA impairs reconstitution of BM-derived Tregs and increases the liability to chronic GVHD. The choice of immunosuppression, such as calcineurin inhibitor-free GVHD prophylaxis with mTOR inhibitor, may have important implications for the control of chronic GVHD after BMT.
en-copyright=
kn-copyright=

en-aut-name=SugiyamaHaruko
en-aut-sei=Sugiyama
en-aut-mei=Haruko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=NishimoriHisakazu
en-aut-sei=Nishimori
en-aut-mei=Hisakazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=YamasujiYoshiko
en-aut-sei=Yamasuji
en-aut-mei=Yoshiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=MatsuokaKen-ichi
en-aut-sei=Matsuoka
en-aut-mei=Ken-ichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=KondoEisei
en-aut-sei=Kondo
en-aut-mei=Eisei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=ShinagawaKatsuji
en-aut-sei=Shinagawa
en-aut-mei=Katsuji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=TanakaTakehiro
en-aut-sei=Tanaka
en-aut-mei=Takehiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=TakeuchiKengo
en-aut-sei=Takeuchi
en-aut-mei=Kengo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=TeshimaTakanori
en-aut-sei=Teshima
en-aut-mei=Takanori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=TanimotoMitsune
en-aut-sei=Tanimoto
en-aut-mei=Mitsune
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

affil-num=1
en-affil=
kn-affil=Okayama Univ, Gradu Sch Med Dent & Pharmaceut Sci, Dept Hematol & Oncol

affil-num=2
en-affil=
kn-affil=Okayama Univ, Gradu Sch Med Dent & Pharmaceut Sci, Dept Hematol & Oncol

affil-num=3
en-affil=
kn-affil=Okayama Univ, Gradu Sch Med Dent & Pharmaceut Sci, Dept Hematol & Oncol

affil-num=4
en-affil=
kn-affil=Okayama Univ, Gradu Sch Med Dent & Pharmaceut Sci, Dept Hematol & Oncol

affil-num=5
en-affil=
kn-affil=Okayama Univ, Gradu Sch Med Dent & Pharmaceut Sci, Dept Hematol & Oncol

affil-num=6
en-affil=
kn-affil=Okayama Univ, Gradu Sch Med Dent & Pharmaceut Sci, Dept Hematol & Oncol

affil-num=7
en-affil=
kn-affil=Okayama Univ, Gradu Sch Med Dent & Pharmaceut Sci, Dept Hematol & Oncol

affil-num=8
en-affil=
kn-affil=Okayama Univ, Gradu Sch Med Dent & Pharmaceut Sci, Dept Hematol & Oncol

affil-num=9
en-affil=
kn-affil=Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol

affil-num=10
en-affil=
kn-affil=Japanese Fdn Canc Res, Inst Canc, Pathol Project Mol Target

affil-num=11
en-affil=
kn-affil=Hokkaido Univ, Dept Hematol

affil-num=12
en-affil=
kn-affil=Okayama Univ, Gradu Sch Med Dent & Pharmaceut Sci, Dept Hematol & Oncol
en-keyword=Chronic graft-versus-host disease (GVHD)
kn-keyword=Chronic graft-versus-host disease (GVHD)
en-keyword=Cyclosporine
kn-keyword=Cyclosporine
en-keyword=Mammalian target of rapamycin (mTOR) inhibitor
kn-keyword=Mammalian target of rapamycin (mTOR) inhibitor
en-keyword=Regulatory T cell
kn-keyword=Regulatory T cell
END

start-ver=1.4
cd-journal=joma
no-vol=100
cd-vols=
no-issue=2
article-no=
start-page=254
end-page=257
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=201207
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Histological and immunohistochemical features of gingival enlargement in a patient with AML
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Here, we discuss the pathophysiology of leukemia-associated gingival enlargement based on a case of acute myelomonocytic leukemia (AML-M4) with typical gingival enlargement. Uniquely, this patient was well enough to allow full periodontal examination and incisional gingival biopsy to be performed both before and after chemotherapy. The patient was a 39-year-old Japanese woman with AML-M4 showing gingival enlargement. Histological and immunohistochemical features of gingiva and bacterial counts in the periodontal pockets were examined before and after chemotherapy. The results were as follows: (1) infiltration of myelomonocytic blasts in enlarged gingiva; (2) resolution of gingival enlargement with complete remission of AML by anticancer chemotherapy; and (3) the numbers of bacteria in the periodontal pockets were not high and were not altered before or after chemotherapy. In patients with AML-M4, remarkable mucosal enlargement is not generally observed in the body except in the gingiva. We hypothesized that antigens derived from periodontal bacteria, even if they are not present in large numbers, could act as chemoattractants for myelomonocytic leukemic cells.
en-copyright=
kn-copyright=

en-aut-name=SonoiNorihiro
en-aut-sei=Sonoi
en-aut-mei=Norihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=SogaYoshihiko
en-aut-sei=Soga
en-aut-mei=Yoshihiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=MaedaHiroshi
en-aut-sei=Maeda
en-aut-mei=Hiroshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=IchimuraKoichi
en-aut-sei=Ichimura
en-aut-mei=Koichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=YoshinoTadashi
en-aut-sei=Yoshino
en-aut-mei=Tadashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=AoyamaKazutoshi
en-aut-sei=Aoyama
en-aut-mei=Kazutoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=MaedaYoshinobu
en-aut-sei=Maeda
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=TanimotoMitsune
en-aut-sei=Tanimoto
en-aut-mei=Mitsune
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=LoganRichard
en-aut-sei=Logan
en-aut-mei=Richard
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=Raber-DurlacherJudith
en-aut-sei=Raber-Durlacher
en-aut-mei=Judith
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=TakashibaShogo
en-aut-sei=Takashiba
en-aut-mei=Shogo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

affil-num=1
en-affil=
kn-affil=Okayama Univ, Dept Pathophysiol Periodontal Sci, Grad Sch Med Dent & Pharmaceut Sci

affil-num=2
en-affil=
kn-affil=Okayama Univ Hosp, Cent Clin Dept, Div Hosp Dent

affil-num=3
en-affil=
kn-affil=Okayama Univ, Dept Pathophysiol Periodontal Sci, Grad Sch Med Dent & Pharmaceut Sci

affil-num=4
en-affil=
kn-affil=Okayama Univ, Dept Pathol, Grad Sch Med Dent & Pharmaceut Sci

affil-num=5
en-affil=
kn-affil=Okayama Univ, Dept Pathol, Grad Sch Med Dent & Pharmaceut Sci

affil-num=6
en-affil=
kn-affil=Okayama Univ, Dept Hematol Oncol & Resp Med, Grad Sch Med Dent & Pharmaceut Sci

affil-num=7
en-affil=
kn-affil=Okayama Univ, Dept Hematol Oncol & Resp Med, Grad Sch Med Dent & Pharmaceut Sci

affil-num=8
en-affil=
kn-affil=Okayama Univ, Dept Hematol Oncol & Resp Med, Grad Sch Med Dent & Pharmaceut Sci

affil-num=9
en-affil=
kn-affil=Okayama Univ, Dept Hematol Oncol & Resp Med, Grad Sch Med Dent & Pharmaceut Sci

affil-num=10
en-affil=
kn-affil=Univ Adelaide, Fac Hlth Sci, Sch Dent

affil-num=11
en-affil=
kn-affil=Acad Ctr Dent Amsterdam, Dept Periodontol

affil-num=12
en-affil=
kn-affil=Okayama Univ, Dept Pathophysiol Periodontal Sci, Grad Sch Med Dent & Pharmaceut Sci
en-keyword=Gingival enlargement
kn-keyword=Gingival enlargement
en-keyword=Acute myelomonocytic leukemia
kn-keyword=Acute myelomonocytic leukemia
en-keyword=Pathogenesis
kn-keyword=Pathogenesis
en-keyword=Histology
kn-keyword=Histology
en-keyword=Immunohistochemistry
kn-keyword=Immunohistochemistry
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2014
dt-pub=20140325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Integrin阻害剤cilengitideはvasculostatin発現腫瘍溶解性ウイルスの抗グリオーマ効果を強化する
kn-title=The integrin inhibitor cilengitide enhances the anti-glioma efficacy of vasculostatin-expressing oncolytic virus
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiKentaro
en-aut-sei=Fujii
en-aut-mei=Kentaro
kn-aut-name=藤井謙太郎
kn-aut-sei=藤井
kn-aut-mei=謙太郎
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=39
cd-vols=
no-issue=2
article-no=
start-page=332
end-page=339
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=199603
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=先天股脱保存療法後の造影所見 特に前方関節唇と股関節成長の関連について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=観血的治療を加えた先天股脱症例で術中所見の得られた2方向造影を参考として,保存的治療例の造影所見を検討した.対象は保存的治療後10年以上経過観察した27例32股と観血的治療をした14例15股である.2方向造影分類は藤井の分類に従い,最終調査時評価はSeverinのX線判定基準を用いた.保存的治療例のType A-1は18股で最終調査時は全てSeverin Iであった.観血的治療を受けた14例の術中所見は全例手術時臼底に介在物を認めた.前方関節唇の2方向造影所見と手術所見では15股中13股で一致した.以上より,2方向造影像は術中所見とよく一致する為,遺残性亜脱臼に対する手術適応を決定する一つの指標となりうる
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=平井成幸
kn-aut-sei=平井
kn-aut-mei=成幸
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=45
cd-vols=
no-issue=3
article-no=
start-page=17
end-page=31
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=20131220
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=`Flexible Specialization' Revisited: A Case Study of　Denim Jeans Production in a Japanese Industrial District
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Humanities and Social Sciences, Okayama University
kn-affil=岡山大学大学院社会文化科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=20130930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=肝門部胆悪性道狭窄に対して留置したメタリックステントの閉塞時のマネージメント
kn-title=Management of Occluded Metallic Stents in Malignant Hilar Biliary Stricture
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiMasakuni
en-aut-sei=Fujii
en-aut-mei=Masakuni
kn-aut-name=藤井雅邦
kn-aut-sei=藤井
kn-aut-mei=雅邦
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=T4-6 2
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=201308
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Strength and Durability of Concrete with Blast Furnace Slag
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The properties of concrete using blast furnace as binder and fine aggregate have been
investigated in this study. The experiments focus on the properties of concrete such as
compressive strength and young's modulus, carbonation, diffusion of chloride ions,
resistance to sulfate attack and resistance to freeze and thaw. The experimental results show
that when blast furnace slag is used in concrete, it improves the durability properties of
concrete. However, the combination of using both blast furnace slag as binder and fine
aggregate shows a greater improvement of those properties of concrete.
en-copyright=
kn-copyright=

en-aut-name=JARIYATHITIPONGPaweena
en-aut-sei=JARIYATHITIPONG
en-aut-mei=Paweena
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=HOSOTANIKazuyoshi
en-aut-sei=HOSOTANI
en-aut-mei=Kazuyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=FUJIITakashi
en-aut-sei=FUJII
en-aut-mei=Takashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=AYANOToshiki
en-aut-sei=AYANO
en-aut-mei=Toshiki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=Landes Co., Ltd

affil-num=2
en-affil=
kn-affil=Landes Co., Ltd

affil-num=3
en-affil=
kn-affil=Okayama University

affil-num=4
en-affil=
kn-affil=Okayama University
en-keyword=Ground granulated blast furnace slag
kn-keyword=Ground granulated blast furnace slag
en-keyword=Blast furnace slag sand
kn-keyword=Blast furnace slag sand
en-keyword=Carbonation
kn-keyword=Carbonation
en-keyword=Drying shrinkage strain
kn-keyword=Drying shrinkage strain
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=W1-7 3
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=201308
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Effect of chemical admixture on property of fresh mortar using sludge water
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Addition of sludge water as a part of mixing water had little influence on strength and
durability of hardened concrete, but caused a slump decrease of fresh concrete. The decrease
of slump was improved by addition of a certain set retarder such as gluconate into sludge
water due to control of cement hydration. Some of polymers were also effective in
improvement of slump. However hydration of cement was observed in those cases of
polymers. Therefore it is presumed such the polymers improve slump not by hydration
control effect but by another one.
en-copyright=
kn-copyright=

en-aut-name=FUJIITakashi
en-aut-sei=FUJII
en-aut-mei=Takashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=SAITOTadashi
en-aut-sei=SAITO
en-aut-mei=Tadashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=AYANOToshiki
en-aut-sei=AYANO
en-aut-mei=Toshiki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=Okayama University

affil-num=2
en-affil=
kn-affil=Nagao & Co., Ltd.

affil-num=3
en-affil=
kn-affil=Okayama University
en-keyword=Sludge water
kn-keyword=Sludge water
en-keyword=Mortarflow
kn-keyword=Mortarflow
en-keyword=Organic compound
kn-keyword=Organic compound
en-keyword=Polymer
kn-keyword=Polymer
en-keyword=Sludge sedimentation
kn-keyword=Sludge sedimentation
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=581
end-page=586
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=201305
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=THE SULFURIC ACID RESISTANCE OF CONCRETE WITH BLAST FURNACE SLAG
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The deterioration of concrete by sulfuric acid attack in sewage environments has become a serious problem. In this
study, it was shown that the resistance to sulfuric acid of mortar and concrete can be improved by using a
blast-furnace slag fine aggregate to the total amount of fine aggregate. When mortar or concrete reacts to sulfuric
acid, dihydrated gypsum film is formed around the particulate of the fine aggregate. This dihydrated gypsum film
could retard the penetration of sulfuric acid, thus improving the resistance to sulfuric acid. However, the resistance
to sulfuric acid depends on the hardness of the dihydrated gypsum film.
en-copyright=
kn-copyright=

en-aut-name=JARIYATHITIPONGPaweena
en-aut-sei=JARIYATHITIPONG
en-aut-mei=Paweena
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=HOSOTANIKazuyoshi
en-aut-sei=HOSOTANI
en-aut-mei=Kazuyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=FUJIITakashi
en-aut-sei=FUJII
en-aut-mei=Takashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=AYANOToshiki
en-aut-sei=AYANO
en-aut-mei=Toshiki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=Research Engineer, Research and Development Labolatory, Landes Co.,Ltd

affil-num=2
en-affil=
kn-affil=Manager, Technology Center, Landes Co.,Ltd

affil-num=3
en-affil=
kn-affil=Assistant Professor, Division of Environmental Science, Graduate School of Environmental and Life Science, Okayama University

affil-num=4
en-affil=
kn-affil=Professor, Division of Environmental Science, Graduate School of Environmental and Life Science, Okayama University
en-keyword=sulfuric acid attack
kn-keyword=sulfuric acid attack
en-keyword=blast furnace slag sand
kn-keyword=blast furnace slag sand
en-keyword=ground granulated blast furnace slag
kn-keyword=ground granulated blast furnace slag
en-keyword=gypsum
kn-keyword=gypsum
en-keyword=sewerage
kn-keyword=sewerage
END

start-ver=1.4
cd-journal=joma
no-vol=13
cd-vols=
no-issue=
article-no=
start-page=1
end-page=6
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=201311
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effect of Blast Furnace Slag Sand to Durability of Concrete
kn-title=コンクリートの耐久性に及ぼす高炉スラグ細骨材の影響
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=本研究は，高炉スラグを用いたコンクリートの中性化，耐硫酸塩性および凍結融解
抵抗性の検討を行ったものである．高炉スラグを細骨材に用いることで，細骨材周辺に集
積する水酸化カルシウムがなくなり，骨材表面とペーストとの界面が強固なものとなるた
め，コンクリートの中性化および耐硫酸塩性が向上する．また，結合材の一部を高炉スラ
グ微粉末に置き換えるか，または，細骨材に高炉スラグ細骨材を用いたコンクリートでは，
AE 剤を用いることなく，また，蒸気養生を行っても，十分な凍結融解抵抗性が得られる．
en-copyright=
kn-copyright=

en-aut-name=FUJIITakashi
en-aut-sei=FUJII
en-aut-mei=Takashi
kn-aut-name=藤井隆史
kn-aut-sei=藤井
kn-aut-mei=隆史
aut-affil-num=1
ORCID=

en-aut-name=JARIYATHITIPONGPaweena
en-aut-sei=JARIYATHITIPONG
en-aut-mei=Paweena
kn-aut-name=ジャリヤティティポンパウィナ
kn-aut-sei=ジャリヤティティポン
kn-aut-mei=パウィナ
aut-affil-num=2
ORCID=

en-aut-name=HOSOTANIKazuyoshi
en-aut-sei=HOSOTANI
en-aut-mei=Kazuyoshi
kn-aut-name=細谷多慶
kn-aut-sei=細谷
kn-aut-mei=多慶
aut-affil-num=3
ORCID=

en-aut-name=AYANOToshiki
en-aut-sei=AYANO
en-aut-mei=Toshiki
kn-aut-name=綾野克紀
kn-aut-sei=綾野
kn-aut-mei=克紀
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院環境生命科学研究科環境科学専攻

affil-num=2
en-affil=
kn-affil=ランデス株式会社本部技術センター研究所

affil-num=3
en-affil=
kn-affil=ランデス株式会社本部技術センター

affil-num=4
en-affil=
kn-affil=岡山大学大学院環境生命科学研究科環境科学専攻
en-keyword=高炉スラグ細骨材
kn-keyword=高炉スラグ細骨材
en-keyword=中性化
kn-keyword=中性化
en-keyword=耐硫酸塩性
kn-keyword=耐硫酸塩性
en-keyword=凍結融解抵抗性
kn-keyword=凍結融解抵抗性
END

start-ver=1.4
cd-journal=joma
no-vol=125
cd-vols=
no-issue=2
article-no=
start-page=109
end-page=112
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=20130801
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Therapeutic effects of redox-active protein thioredoxin(TRX)-1 in influenza-virus-induced pneumonia in mice
kn-title=マウスインフルエンザ肺炎におけるレドックス制御蛋白チオレドキシン（TRX-1）の治療的効果
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=YashiroMasato
en-aut-sei=Yashiro
en-aut-mei=Masato
kn-aut-name=八代将登
kn-aut-sei=八代
kn-aut-mei=将登
aut-affil-num=1
ORCID=

en-aut-name=TsukaharaHirokazu
en-aut-sei=Tsukahara
en-aut-mei=Hirokazu
kn-aut-name=塚原宏一
kn-aut-sei=塚原
kn-aut-mei=宏一
aut-affil-num=2
ORCID=

en-aut-name=MatsukawaAkihiro
en-aut-sei=Matsukawa
en-aut-mei=Akihiro
kn-aut-name=松川昭博
kn-aut-sei=松川
kn-aut-mei=昭博
aut-affil-num=3
ORCID=

en-aut-name=YamadaMutsuko
en-aut-sei=Yamada
en-aut-mei=Mutsuko
kn-aut-name=山田睦子
kn-aut-sei=山田
kn-aut-mei=睦子
aut-affil-num=4
ORCID=

en-aut-name=FujiiYosuke
en-aut-sei=Fujii
en-aut-mei=Yosuke
kn-aut-name=藤井洋輔
kn-aut-sei=藤井
kn-aut-mei=洋輔
aut-affil-num=5
ORCID=

en-aut-name=NagaokaYoshiharu
en-aut-sei=Nagaoka
en-aut-mei=Yoshiharu
kn-aut-name=長岡義晴
kn-aut-sei=長岡
kn-aut-mei=義晴
aut-affil-num=6
ORCID=

en-aut-name=TsugeMitsuru
en-aut-sei=Tsuge
en-aut-mei=Mitsuru
kn-aut-name=津下充
kn-aut-sei=津下
kn-aut-mei=充
aut-affil-num=7
ORCID=

en-aut-name=YamashitaNobuko
en-aut-sei=Yamashita
en-aut-mei=Nobuko
kn-aut-name=山下信子
kn-aut-sei=山下
kn-aut-mei=信子
aut-affil-num=8
ORCID=

en-aut-name=ItoToshihiro
en-aut-sei=Ito
en-aut-mei=Toshihiro
kn-aut-name=伊藤利洋
kn-aut-sei=伊藤
kn-aut-mei=利洋
aut-affil-num=9
ORCID=

en-aut-name=YamadaMasao
en-aut-sei=Yamada
en-aut-mei=Masao
kn-aut-name=山田雅夫
kn-aut-sei=山田
kn-aut-mei=雅夫
aut-affil-num=10
ORCID=

en-aut-name=MasutaniHiroshi
en-aut-sei=Masutani
en-aut-mei=Hiroshi
kn-aut-name=増谷弘
kn-aut-sei=増谷
kn-aut-mei=弘
aut-affil-num=11
ORCID=

en-aut-name=YodoiJunji
en-aut-sei=Yodoi
en-aut-mei=Junji
kn-aut-name=淀井淳司
kn-aut-sei=淀井
kn-aut-mei=淳司
aut-affil-num=12
ORCID=

en-aut-name=MorishimaTsuneo
en-aut-sei=Morishima
en-aut-mei=Tsuneo
kn-aut-name=森島恒雄
kn-aut-sei=森島
kn-aut-mei=恒雄
aut-affil-num=13
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 小児医科学

affil-num=2
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 小児医科学

affil-num=3
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 病理学（免疫病理）

affil-num=4
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 小児医科学

affil-num=5
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 小児医科学

affil-num=6
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 小児医科学

affil-num=7
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 小児医科学

affil-num=8
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 小児医科学

affil-num=9
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 病理学（免疫病理）

affil-num=10
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 病原ウイルス学

affil-num=11
en-affil=
kn-affil=京都大学ウイルス研究所 生体応答学研究部門

affil-num=12
en-affil=
kn-affil=京都大学ウイルス研究所 生体応答学研究部門

affil-num=13
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 小児医科学
en-keyword=acute lung injury
kn-keyword=acute lung injury
en-keyword=cytokine
kn-keyword=cytokine
en-keyword=influenza virus
kn-keyword=influenza virus
en-keyword=oxidative stress
kn-keyword=oxidative stress
en-keyword=thioredoxin-1
kn-keyword=thioredoxin-1
END

start-ver=1.4
cd-journal=joma
no-vol=167
cd-vols=
no-issue=2
article-no=
start-page=252
end-page=261
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=201208
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Detection of antibodies against the non-calcium-dependent epitopes of desmoglein 3 in pemphigus vulgaris and their pathogenic significance
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Background Antidesmoglein (anti-Dsg) 3 serum antibody titres are usually correlated with the disease activity of pemphigus vulgaris (PV), but some patients retain high titres even in remission. 

Objectives The aim of our study was to determine whether anti-Dsg3 antibodies in PV sera recognized calcium (Ca2+)-dependent or non-Ca2+-dependent epitopes, and to evaluate their pathogenicity. 

Methods Dsg3 baculoprotein-coated enzyme-linked immunosorbent assay (ELISA) plates were treated with 0.5 mmol L-1 ethylenediaminetetraacetic acid (EDTA). The binding ability of anti-Dsg3 monoclonal antibodies (mAbs) was analysed. Eight of the 83 patients with PV who were screened had elevated Dsg3 ELISA index values > 100 in remission. The binding ability of these PV sera was analysed. We evaluated the pathogenicity of anti-Dsg3 serum antibodies against the non-Ca2+-dependent epitopes using a dissociation assay. 

Results The reactivity of pathogenic anti-Dsg3 mAbs against the Ca2+-dependent epitopes diminished markedly in the EDTA-treated ELISA, whereas no such reduction was observed in mAbs against the non-Ca2+-dependent epitopes. The sera of all the patients contained antibodies against both Ca2+-dependent and non-Ca2+-dependent epitopes. In six out of the eight patients, the ratio of antibodies against Ca2+-dependent to non-Ca2+-dependent epitopes decreased in remission. EDTA-treated Dsg3 baculoproteins adsorbed anti-Dsg3 serum antibodies against the non-Ca2+-dependent epitopes, but the remnant PV antibodies retained the ability to induce acantholysis in the dissociation assay. 

Conclusions We have established an assay to measure indirectly the titres of anti-Dsg3 serum antibodies against the Ca2+-dependent epitopes, based on the differences between EDTA-untreated and EDTA-treated ELISA index values, as a routine laboratory test to reflect the pathogenic anti-Dsg3 serum antibody titres more accurately.
en-copyright=
kn-copyright=

en-aut-name=KamiyaK
en-aut-sei=Kamiya
en-aut-mei=K
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=AoyamaY
en-aut-sei=Aoyama
en-aut-mei=Y
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=ShirafujiY
en-aut-sei=Shirafuji
en-aut-mei=Y
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=HamadaT
en-aut-sei=Hamada
en-aut-mei=T
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=MorizaneS
en-aut-sei=Morizane
en-aut-mei=S
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=FujiiK
en-aut-sei=Fujii
en-aut-mei=K
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=HisataK
en-aut-sei=Hisata
en-aut-mei=K
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=IwatsukiK
en-aut-sei=Iwatsuki
en-aut-mei=K
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=Okayama Univ, Dept Dermatol, Grad Sch Med Dent & Pharmaceut Sci

affil-num=2
en-affil=
kn-affil=Okayama Univ, Dept Dermatol, Grad Sch Med Dent & Pharmaceut Sci

affil-num=3
en-affil=
kn-affil=Okayama Univ, Dept Dermatol, Grad Sch Med Dent & Pharmaceut Sci

affil-num=4
en-affil=
kn-affil=Okayama Univ, Dept Dermatol, Grad Sch Med Dent & Pharmaceut Sci

affil-num=5
en-affil=
kn-affil=Okayama Univ, Dept Dermatol, Grad Sch Med Dent & Pharmaceut Sci

affil-num=6
en-affil=
kn-affil=Okayama Univ, Dept Dermatol, Grad Sch Med Dent & Pharmaceut Sci

affil-num=7
en-affil=
kn-affil=Okayama Univ, Dept Dermatol, Grad Sch Med Dent & Pharmaceut Sci

affil-num=8
en-affil=
kn-affil=Okayama Univ, Dept Dermatol, Grad Sch Med Dent & Pharmaceut Sci
END

start-ver=1.4
cd-journal=joma
no-vol=18
cd-vols=
no-issue=3
article-no=
start-page=395
end-page=398
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2010
dt-pub=201003
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Total bacterial counts on oral mucosa after using a commercial saliva substitute in patients undergoing hematopoietic cell transplantation
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The commercial saliva substitute OralbalanceA (R) has been reported to alleviate symptoms of postradiotherapy xerostomia in head and neck cancer patients. OralbalanceA (R) may also be effective for xerostomia in patients undergoing hematopoietic cell transplantation (HCT) with high-dose chemotherapy and total-body irradiation. However, HCT patients are in a severely compromised condition, and saliva substitute must not promote infection. We reported previously that OralbalanceA (R) has antimicrobial effects against microbial species detected during HCT in vitro. This study was performed to determine the in vivo effects of OralbalanceA (R) on oral mucosal total bacterial counts in patients undergoing HCT. 

A total of 18 neutropenic patients undergoing HCT were enrolled in this study. Before and after 1 week of OralbalanceA (R) use, bacterial samples were obtained from patients by wiping an area of I center dot 1 cm on the buccal mucosa with sterilized cotton swabs. Total bacterial counts of the obtained samples were examined by quantitative polymerase chain reaction amplification of the bacterial 16S ribosomal RNA gene. As controls, bacterial samples were also obtained from ten healthy subjects, and total bacterial counts were examined. 

No significant increase in bacterial count was observed with use of OralbalanceA (R). None of the patients showed bacterial counts above the range found in healthy controls after using OralbalanceA (R). 

In neutropenic patients undergoing HCT, OralbalanceA (R) did not increase the total counts of oral mucosal bacteria beyond the range found in healthy controls. Oral care using OralbalanceA (R) may alleviate the symptoms induced by hyposalivation without promoting infection.
en-copyright=
kn-copyright=

en-aut-name=SugiuraYuko
en-aut-sei=Sugiura
en-aut-mei=Yuko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=SogaYoshihiko
en-aut-sei=Soga
en-aut-mei=Yoshihiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=YamabeKokoro
en-aut-sei=Yamabe
en-aut-mei=Kokoro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=TsutaniSoichiro
en-aut-sei=Tsutani
en-aut-mei=Soichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=TanimotoIchiro
en-aut-sei=Tanimoto
en-aut-mei=Ichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=MaedaHiroshi
en-aut-sei=Maeda
en-aut-mei=Hiroshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=KokeguchiSusumu
en-aut-sei=Kokeguchi
en-aut-mei=Susumu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=IshimaruFumihiko
en-aut-sei=Ishimaru
en-aut-mei=Fumihiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=TanimotoMitsune
en-aut-sei=Tanimoto
en-aut-mei=Mitsune
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=NishimuraFusanori
en-aut-sei=Nishimura
en-aut-mei=Fusanori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=TakashibaShogo
en-aut-sei=Takashiba
en-aut-mei=Shogo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

affil-num=1
en-affil=
kn-affil=Okayama Univ

affil-num=2
en-affil=
kn-affil=Okayama Univ

affil-num=3
en-affil=
kn-affil=Okayama Univ

affil-num=4
en-affil=
kn-affil=Okayama Univ

affil-num=5
en-affil=
kn-affil=Okayama Univ

affil-num=6
en-affil=
kn-affil=Okayama Univ

affil-num=7
en-affil=
kn-affil=Okayama Univ

affil-num=8
en-affil=
kn-affil=Okayama Univ

affil-num=9
en-affil=
kn-affil=Okayama Univ

affil-num=10
en-affil=
kn-affil=Okayama Univ

affil-num=11
en-affil=
kn-affil=Okayama Univ

affil-num=12
en-affil=
kn-affil=Okayama Univ
en-keyword=Hematopoietic cell transplantation
kn-keyword=Hematopoietic cell transplantation
en-keyword=Xerostomia
kn-keyword=Xerostomia
en-keyword=Saliva substitute
kn-keyword=Saliva substitute
END

start-ver=1.4
cd-journal=joma
no-vol=16
cd-vols=
no-issue=10
article-no=
start-page=1197
end-page=1200
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=200810
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Evaluation of xerostomia in hematopoietic cell transplantation by a simple capacitance method device
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Goals Hematopoietic cell transplantation (HCT) may lead to the development of xerostomia. However, there have been few reports of xerostomia in HCT patients based on objective data. We investigated moisture in the oral mucosa in patients undergoing HCT by the capacitance method using a convenient device, Moisture Checker for Mucus (R) (MCM; Life Co., Ltd., Saitama, Japan). 

Subjects and methods Thirty-six patients undergoing HCT at Okayama University Hospital of Medicine and Dentistry (Male=22, Female=14; age=41.6 +/- 16.2 years old) were enrolled in this study. Moisture in the oral mucosa was measured by MCM in accordance with the manufacturer's instructions. The results were obtained as MCM values (%), which are the weight percentage of water content in the oral mucosal epithelium. As controls, moisture of the oral mucosa was also examined in healthy volunteers (Male=27, Female=35; age=43.0 +/- 14.6 years old). 

Main results Throughout the examination period, MCM values were significantly lower in patients who underwent HCT than in controls. The degree of mucosal moisture in HCT patients showed wide interindividual differences. 

Conclusion The degree of mucosal moisture in HCT patients was low and showed wide interindividual differences. Evaluation of xerostomia using such a device may contribute to appropriate oral care with saliva substitute.
en-copyright=
kn-copyright=

en-aut-name=SugiuraYuko
en-aut-sei=Sugiura
en-aut-mei=Yuko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=SogaYoshihiko
en-aut-sei=Soga
en-aut-mei=Yoshihiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=NishideSachiko
en-aut-sei=Nishide
en-aut-mei=Sachiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=KonoKotoe
en-aut-sei=Kono
en-aut-mei=Kotoe
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=TakahashiKanayo
en-aut-sei=Takahashi
en-aut-mei=Kanayo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=IshimaruFumihiko
en-aut-sei=Ishimaru
en-aut-mei=Fumihiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=TanimotoMitsune
en-aut-sei=Tanimoto
en-aut-mei=Mitsune
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=NishimuraFusanori
en-aut-sei=Nishimura
en-aut-mei=Fusanori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=TakashibaShogo
en-aut-sei=Takashiba
en-aut-mei=Shogo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=Okayama Univ

affil-num=2
en-affil=
kn-affil=Okayama Univ

affil-num=3
en-affil=
kn-affil=Okayama Univ Hosp Med & Dent

affil-num=4
en-affil=
kn-affil=Okayama Univ Hosp Med & Dent

affil-num=5
en-affil=
kn-affil=Okayama Univ Hosp Med & Dent

affil-num=6
en-affil=
kn-affil=Okayama Univ

affil-num=7
en-affil=
kn-affil=Okayama Univ

affil-num=8
en-affil=
kn-affil=Okayama Univ

affil-num=9
en-affil=
kn-affil=Okayama Univ

affil-num=10
en-affil=
kn-affil=Okayama Univ
en-keyword=xerostomia
kn-keyword=xerostomia
en-keyword=hematopoietic cell transplantation
kn-keyword=hematopoietic cell transplantation
en-keyword=hyposalivation
kn-keyword=hyposalivation
END

start-ver=1.4
cd-journal=joma
no-vol=16
cd-vols=
no-issue=4
article-no=
start-page=421
end-page=424
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=200804
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Antimicrobial effects of the saliva substitute, Oralbalance (R), against microorganisms from oral mucosa in the hematopoietic cell transplantation period
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Goals The commercially available saliva substitute Oralbalance (R) has been reported to alleviate symptoms of post-radiotherapy xerostomia in head and neck cancer patients. Oralbalance (R) may also be effective for xerostomia in patients undergoing hematopoietic cell transplantation (HCT) with high-dose chemotherapy and total-body irradiation. However, HCT patients are severely compromised, and saliva substitute must therefore not promote infection. This study was performed to determine the effects of Oralbalance (R) on microbial species identified during HCT. 

Patients and methods Microbial identification of oral mucosa was performed in 28 patients undergoing HCT. The antimicrobial effects of Oralbalance (R) against bacteria and fungi detected in the HCT period were examined in vitro. Briefly, bacteria and fungi were spread on agar plates, and 0.1g of Oralbalance (R) gel was applied (about phi 1cm). After incubation at 37 degrees C for 24h, the presence of a transparent zone of inhibition around Oralbalance (R) was observed. 

Main results Not only bacterial species constituting normal flora of the oral mucosa but also those not usually constituting normal flora, e.g., coagulase-negative Staphylococcus, were detected. A transparent zone was observed around Oralbalance (R) in all bacterial species examined. No transparent zone was observed for Candida albicans, but growth was inhibited in the area where Oralbalance (R) was applied. 

Conclusions Oralbalance (R) does not facilitate increases in microorganisms in the HCT period. Oral care with Oralbalance (R) does not promote infection in patients undergoing HCT.
en-copyright=
kn-copyright=

en-aut-name=SugiuraYuko
en-aut-sei=Sugiura
en-aut-mei=Yuko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=SogaYoshihiko
en-aut-sei=Soga
en-aut-mei=Yoshihiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=TanimotoIchiro
en-aut-sei=Tanimoto
en-aut-mei=Ichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=KokeguchiSusumu
en-aut-sei=Kokeguchi
en-aut-mei=Susumu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=NishideSachiko
en-aut-sei=Nishide
en-aut-mei=Sachiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=KonoKotoe
en-aut-sei=Kono
en-aut-mei=Kotoe
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=TakahashiKanayo
en-aut-sei=Takahashi
en-aut-mei=Kanayo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=FujiiNobuharu
en-aut-sei=Fujii
en-aut-mei=Nobuharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=IshimaruFumihiko
en-aut-sei=Ishimaru
en-aut-mei=Fumihiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=TanimotoMitsune
en-aut-sei=Tanimoto
en-aut-mei=Mitsune
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=YamabeKokoro
en-aut-sei=Yamabe
en-aut-mei=Kokoro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=TsutaniSoichiro
en-aut-sei=Tsutani
en-aut-mei=Soichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=NishimuraFusanori
en-aut-sei=Nishimura
en-aut-mei=Fusanori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

en-aut-name=TakashibaShogo
en-aut-sei=Takashiba
en-aut-mei=Shogo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=

affil-num=1
en-affil=
kn-affil=Okayama Univ

affil-num=2
en-affil=
kn-affil=Okayama Univ

affil-num=3
en-affil=
kn-affil=Okayama Univ

affil-num=4
en-affil=
kn-affil=Okayama Univ

affil-num=5
en-affil=
kn-affil=Okayama Univ Hosp

affil-num=6
en-affil=
kn-affil=Okayama Univ Hosp

affil-num=7
en-affil=
kn-affil=Okayama Univ Hosp

affil-num=8
en-affil=
kn-affil=Okayama Univ

affil-num=9
en-affil=
kn-affil=Okayama Univ

affil-num=10
en-affil=
kn-affil=Okayama Univ

affil-num=11
en-affil=
kn-affil=Okayama Univ

affil-num=12
en-affil=
kn-affil=Okayama Univ

affil-num=13
en-affil=
kn-affil=Okayama Univ

affil-num=14
en-affil=
kn-affil=Okayama Univ
en-keyword=Hematopoietic cell transplantation
kn-keyword=Hematopoietic cell transplantation
en-keyword=Xerostomia
kn-keyword=Xerostomia
en-keyword=Saliva substitute
kn-keyword=Saliva substitute
en-keyword=Antimicrobial activity
kn-keyword=Antimicrobial activity
END

start-ver=1.4
cd-journal=joma
no-vol=124
cd-vols=
no-issue=2
article-no=
start-page=149
end-page=153
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120801
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of strangulated ileus caused by transomental hernia with reference to previously reported cases
kn-title=術前診断し得た大網裂孔ヘルニアの一例―本邦報告203例の臨床病理学的検討―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Transomental hernia often develops into strangulated ileus. We report on an 81-year-old man with strangulated ileus due to transomental hernia, diagnosed preoperatively by abdominal CT. The patient was referred to our surgical division because of progressive abdominal pain and vomiting. He had no history of laparotomy. An abdominal CT scan showed dilated small intestinal loops with intraluminal air and strangulated small intestinal loops with engorged mesenteric vessels. We diagnosed this as a strangulated internal hernia due to transomental hernia and conducted an emergency laparotomy. The jejunum had herniated through an abnormal hiatus of the greater omentum to the peritoneal cavity. The strangulated intestinal loop, about 15 cm long, was released and the postoperative course was uneventful. In the absence of a previous laparotomy, the differential diagnosis of intestinal obstruction should include internal hernia. An abdominal CT scan is useful for the preoperative and prompt diagnosis of transomental hernia.
en-copyright=
kn-copyright=

en-aut-name=KimuraYuji
en-aut-sei=Kimura
en-aut-mei=Yuji
kn-aut-name=木村裕司
kn-aut-sei=木村
kn-aut-mei=裕司
aut-affil-num=1
ORCID=

en-aut-name=IwakawaKazuhide
en-aut-sei=Iwakawa
en-aut-mei=Kazuhide
kn-aut-name=岩川和秀
kn-aut-sei=岩川
kn-aut-mei=和秀
aut-affil-num=2
ORCID=

en-aut-name=NishieManabu
en-aut-sei=Nishie
en-aut-mei=Manabu
kn-aut-name=西江学
kn-aut-sei=西江
kn-aut-mei=学
aut-affil-num=3
ORCID=

en-aut-name=InagakiMasaru
en-aut-sei=Inagaki
en-aut-mei=Masaru
kn-aut-name=稲垣優
kn-aut-sei=稲垣
kn-aut-mei=優
aut-affil-num=4
ORCID=

en-aut-name=IwagakiHiromi
en-aut-sei=Iwagaki
en-aut-mei=Hiromi
kn-aut-name=岩垣博巳
kn-aut-sei=岩垣
kn-aut-mei=博巳
aut-affil-num=5
ORCID=

affil-num=1
en-affil=
kn-affil=国立病院機構福山医療センター　外科

affil-num=2
en-affil=
kn-affil=国立病院機構福山医療センター　外科

affil-num=3
en-affil=
kn-affil=国立病院機構福山医療センター　外科

affil-num=4
en-affil=
kn-affil=国立病院機構福山医療センター　外科

affil-num=5
en-affil=
kn-affil=国立病院機構福山医療センター　外科
en-keyword=大網裂孔ヘルニア（transomental hernia）
kn-keyword=大網裂孔ヘルニア（transomental hernia）
en-keyword=絞扼性イレウス（strangulated ileus）
kn-keyword=絞扼性イレウス（strangulated ileus）
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120323
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=衝撃式粉砕法による米粉の製パン性に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiKumiko
en-aut-sei=Fujii
en-aut-mei=Kumiko
kn-aut-name=藤井久美子
kn-aut-sei=藤井
kn-aut-mei=久美子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120323
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=血管周囲交感神経におけるSerotonin(5-HT)の取込み遊離および神経機能に及ぼす影響に関する神経薬理学的研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiHirohito
en-aut-sei=Fujii
en-aut-mei=Hirohito
kn-aut-name=藤井裕士
kn-aut-sei=藤井
kn-aut-mei=裕士
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120323
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=口腔粘膜上皮の癌化過程におけるDkk-3とβ-catenin発現増加と局在変化
kn-title=Dickkopf (Dkk)-3 and β-catenin expressions increased in the transition from normal oral mucosal to oral squamous cell carcinoma
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiMasae
en-aut-sei=Fujii
en-aut-mei=Masae
kn-aut-name=藤井昌江
kn-aut-sei=藤井
kn-aut-mei=昌江
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120323
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=悪性胸膜中皮腫の鑑別診断における胸水中の異常DNAメチル化の解析結果
kn-title=Aberrant DNA methylation profile in pleural fluid for differential diagnosis of malignant pleural mesothelioma
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiMasanori
en-aut-sei=Fujii
en-aut-mei=Masanori
kn-aut-name=藤井昌学
kn-aut-sei=藤井
kn-aut-mei=昌学
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=124
cd-vols=
no-issue=1
article-no=
start-page=9
end-page=13
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120401
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Damus-Kaye-Stansel anastomosis
kn-title=Damus-Kaye-Stansel吻合
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiYasuhiro
en-aut-sei=Fujii
en-aut-mei=Yasuhiro
kn-aut-name=藤井泰宏
kn-aut-sei=藤井
kn-aut-mei=泰宏
aut-affil-num=1
ORCID=

en-aut-name=SanoShunji
en-aut-sei=Sano
en-aut-mei=Shunji
kn-aut-name=佐野俊二
kn-aut-sei=佐野
kn-aut-mei=俊二
aut-affil-num=2
ORCID=

en-aut-name=AraiSadahiko
en-aut-sei=Arai
en-aut-mei=Sadahiko
kn-aut-name=新井禎彦
kn-aut-sei=新井
kn-aut-mei=禎彦
aut-affil-num=3
ORCID=

en-aut-name=KasaharaShingo
en-aut-sei=Kasahara
en-aut-mei=Shingo
kn-aut-name=笠原真悟
kn-aut-sei=笠原
kn-aut-mei=真悟
aut-affil-num=4
ORCID=

en-aut-name=TateishiAtsushi
en-aut-sei=Tateishi
en-aut-mei=Atsushi
kn-aut-name=立石篤史
kn-aut-sei=立石
kn-aut-mei=篤史
aut-affil-num=5
ORCID=

en-aut-name=TakagakiMasami
en-aut-sei=Takagaki
en-aut-mei=Masami
kn-aut-name=高垣昌巳
kn-aut-sei=高垣
kn-aut-mei=昌巳
aut-affil-num=6
ORCID=

en-aut-name=FujitaYasufumi
en-aut-sei=Fujita
en-aut-mei=Yasufumi
kn-aut-name=藤田康文
kn-aut-sei=藤田
kn-aut-mei=康文
aut-affil-num=7
ORCID=

en-aut-name=OzawaSusumu
en-aut-sei=Ozawa
en-aut-mei=Susumu
kn-aut-name=大澤晋
kn-aut-sei=大澤
kn-aut-mei=晋
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学病院　心臓血管外科

affil-num=2
en-affil=
kn-affil=岡山大学病院　心臓血管外科

affil-num=3
en-affil=
kn-affil=岡山大学病院　心臓血管外科

affil-num=4
en-affil=
kn-affil=岡山大学病院　心臓血管外科

affil-num=5
en-affil=
kn-affil=岡山大学病院　心臓血管外科

affil-num=6
en-affil=
kn-affil=岡山大学病院　心臓血管外科

affil-num=7
en-affil=
kn-affil=岡山大学病院　心臓血管外科

affil-num=8
en-affil=
kn-affil=岡山大学病院　心臓血管外科
en-keyword=Damus-Kaye-Stansel吻合
kn-keyword=Damus-Kaye-Stansel吻合
en-keyword=単心室症
kn-keyword=単心室症
en-keyword=心室流出路狭窄
kn-keyword=心室流出路狭窄
en-keyword=肺動脈弁逆流
kn-keyword=肺動脈弁逆流
END

start-ver=1.4
cd-journal=joma
no-vol=34
cd-vols=
no-issue=391
article-no=
start-page=470
end-page=479
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1922
dt-pub=19220831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=遺傳性視神經萎縮ノ一家系ニ就テ
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井清信
kn-aut-sei=藤井
kn-aut-mei=清信
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學眼科教室
END

start-ver=1.4
cd-journal=joma
no-vol=35
cd-vols=
no-issue=396
article-no=
start-page=15
end-page=23
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1923
dt-pub=19230131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=「アクロメガリー」ノ二例「アクロメガリー」ノ眼症状ニ就イテ
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井�C信
kn-aut-sei=藤井
kn-aut-mei=�C信
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學眼科教室
END

start-ver=1.4
cd-journal=joma
no-vol=37
cd-vols=
no-issue=424
article-no=
start-page=538
end-page=548
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1925
dt-pub=19250531
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=?ber die Wirkung des Allyltheobromins
kn-title=結節状角膜變性症ニ就テ
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=HudiiK.
en-aut-sei=Hudii
en-aut-mei=K.
kn-aut-name=藤井清信
kn-aut-sei=藤井
kn-aut-mei=清信
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學眼科學教室
END

start-ver=1.4
cd-journal=joma
no-vol=38
cd-vols=
no-issue=442
article-no=
start-page=1214
end-page=1254
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1926
dt-pub=19261130
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=?ber die heredit?re Missbildungen des Auges beim Kaninchen
kn-title=家兎ニ見ラレタル遺傳性眼畸形ニ就テ
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Verfasser machte eine eingehende Z?chtungsversuche mit einer Kaninchenfamilie durch, welche sich im Auge mit der eigentlichen heredit?ren Missbildungen versehen war. In bezug auf die pathologisch-histologische Erkenntnisse ist es besonders genauer untersucht. Zusammenfassende Resultate sind wie folgende: 1) Unter den 98 Kaninchen, die betreffedem Stammbaume geh?rten, haben 30 Tiere (52 Augen) die verschiedenen Missbildungen. 2) Hauptformen der Missbildungen waren Hydrophthalmus oder Microphthalmus je mit staphylomat?sem Aussehen. 3) Ausser der Strangbildung von Nervenelemente, die sich ophthalmoskopisch dem Arteria hyaloidea ?hnliches Aussehen darstellt, waren noch dazu einzeln Bulbuscyste und Linsentr?bung kombiniert. 4) Mit dem Augenmissbildungen gleichzeitig fand man immer noch die Hydrocephalus imfolge der Entwickelungshemmung im Seite von Telencephalon; das heisst nicht anders als Persistens der microcephalischen und physiologische hydrocephalische Zustandes beim Embryo. 5) Alle Missbildungen dieses Stammes m?ssen von der Entwickelungshemmung der Augenblase herbeigef?hrt sein. 6) Die Entwickelungshemmungen im Gebiete von Auge und Gehirn sind ohne Zweifel auf die Folgezust?nde des Entwickelungsenergiemangels im Zentralnervensysteme zur?ck zuf?hren. 7) Beim gesunden Organismus kann noch die Entwickelungsenergie nicht immer gleich sein.
en-copyright=
kn-copyright=

en-aut-name=HuddiK.
en-aut-sei=Huddi
en-aut-mei=K.
kn-aut-name=藤井清信
kn-aut-sei=藤井
kn-aut-mei=清信
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學眼科學教室
END

start-ver=1.4
cd-journal=joma
no-vol=38
cd-vols=
no-issue=437
article-no=
start-page=633
end-page=667
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1926
dt-pub=19260630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Experimentelle Untersuchungen ?ber sogen. Schlummerzellen der Hornhaut
kn-title=角膜ノ假眠細胞ニ關スル實驗的研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Grawitz und seine Sch?ler behaupteten, dass alle in der Entz?ndung auftretenen Zellen Produkte des Gewebes selbst sein. Nach seiner Ansicht entsteht die Intercellularsubstanz aus hoch-differenzierten Zellprotoplasma, in dem das Chromatin der Kerne nicht nachweisbar ist (Schlummerzellen), und unter gewissen Reizzust?nden z. B. bei Entz?ndungen k?nnen diese Intercellularsubstanz im zelligen Zustand wieder zur?ckkehren (Erwachen der Schlummerzellen). Demnach alle bei der Keratitis und der Hornhauttransplantation in der Hornhaut auftretenen Zellen m?ssen die sog. erwachene Schlummerzellen sein. Ich machte einige experimentelle Untersuchungen ?ber Zell-auftreten in die Hornh?ute. 1. Untersuchungen ?ber experimentellen Keratitis. Durch die Untersuchungen ?ber experimentellen Keratitis nach Kauterisation mit einem Paquelinschen Brenner, nach der Aetzung mit den Silbernitratl?sung, und nach der Karmininjektion in dem Glask?rper bemerkte ich die folgende Tatsachen. 1. Nach der Reizung am fr?hesten an dem Hornhautgeschw?r auftreten die Entz?ndungsspiesse, die gr?sstenteils aus pseudoeosinophile Leukocyten entgestanden sind. 2. Sp?ter beginnt die Einwanderung der Leukocyten von der Peripherie der Hornhaut. 3. Und die Regenerationsspiesse kommen am sp?tsten zum Vorschein. 4. Bei dem Panophthalmie die Zellinfiltration tritt sehr rasch und hochgradig sofort nach der Hornhautruptur auf. 2. Transplantation der besch?digten Hornhaut. Durch den Transplantationsversuch der Hornh?ute, die im voraus mit der Hitze (auf 50°C-100°C), Vertrocknung, Kochsalzl?sung, Formalin, Sublimat, Alkohol, Salpeters?ure und Natronlauge auf verschiedenen Grad gesch?digt werden, hatte ich die folgenden Resultaten beklommen. 1. Unterschied des Sch?digungsgrades hat keine grosse Bedeutung f?r den Auftreten der Zellen in der Hornhaut. 2. Im fr?heren Stadium der Transplantation ist die Infiltration mit polymorphkernigen Leukocyten beherschend aber im sp?teren Stadium wird die Organisation vorwiegend. 3. Wenn die Reizbarkeit der implantierte Hornhaut f?r den Organismus schw?cher ist, so tritt die Organisation fr?her ein. 4. Wenn bei Sch?digung der Hornh?ute die Aufquellung wirkte ein, so tritt die Organisation leicht ein. 5. Die Zellinfiltration beginn immer am Schnittrande oder an der Zerreissungsstelle. 6. Bei Keratitis auftretende Zellen sind vollst?ndig gleich mit der Zellarten, die in Transplantierter Hornhaut einwandern. Aus den obenerw?hnten Tatsachen m?chte ich behaupten dass bei den Keratitis auftretende Infiltrationszellen (die Entz?ndungs- und Regenerationsspiesse) seine Ursprung von Leukocyten, Hornhautk?rperchen und Gef?ssendothel haben und die Grawitzsche Schlummerzellentheorie nicht annehmbar ist.
en-copyright=
kn-copyright=

en-aut-name=HudiiK.
en-aut-sei=Hudii
en-aut-mei=K.
kn-aut-name=藤井清信
kn-aut-sei=藤井
kn-aut-mei=清信
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學眼科學教室
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20110930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=砂地盤の不飽和化による液状化対策に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiNao
en-aut-sei=Fujii
en-aut-mei=Nao
kn-aut-name=藤井直
kn-aut-sei=藤井
kn-aut-mei=直
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=123
cd-vols=
no-issue=3
article-no=
start-page=217
end-page=219
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20111201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=FDG-PET/CT is useful in the diagnosis of early phase Takayasu's arteritis : A case report
kn-title=FDG-PET/CTが診断に有用であった大動脈炎症候群の1例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 60-year-old female patient was admitted to our hospital in April, 2010 because of low-grade fever and malaise for several months. Physical examination on admission revealed no abnormalities except for a body temperature of 37.2℃. Blood examinations showed moderate anemia and a high erythrocyte sedimentation rate. There were no other specific abnormal findings. A systemic CT scan study disclosed diffuse thickening of the artery wall through the ascending, descending and abdominal aorta to the bilateral iliac arteries. In order to evaluate the quality of the vessel lesions, a FDG-PET/CT study was performed and revealed abnormal accumulation of 18F-FDG in the thickened wall, suggesting an inflammatory process in the lesion. Taking all these findings into consideration, we made the diagnosis of Takayasu's arteritis, and treated the patient with prednisolone. The treatment was effective and her symptoms improved. A later CT scan revealed that the artery wall became somewhat thinner. Takayasu's arteritis is a disease whose diagnosis is difficult to make because there are neither specific signs nor diagnostic laboratory findings in its early stage. We found that FDG-PET/CT was helpful in the diagnosis and evaluation of lesions in a patient with Takayasu's arteritis.
en-copyright=
kn-copyright=

en-aut-name=NishiiKazuya
en-aut-sei=Nishii
en-aut-mei=Kazuya
kn-aut-name=西井和也
kn-aut-sei=西井
kn-aut-mei=和也
aut-affil-num=1
ORCID=

en-aut-name=ShigematsuTerunobu
en-aut-sei=Shigematsu
en-aut-mei=Terunobu
kn-aut-name=重松照伸
kn-aut-sei=重松
kn-aut-mei=照伸
aut-affil-num=2
ORCID=

en-aut-name=FujiiSoichiro
en-aut-sei=Fujii
en-aut-mei=Soichiro
kn-aut-name=藤井総一郎
kn-aut-sei=藤井
kn-aut-mei=総一郎
aut-affil-num=3
ORCID=

en-aut-name=MiyashitaKatsuhiro
en-aut-sei=Miyashita
en-aut-mei=Katsuhiro
kn-aut-name=宮下雄博
kn-aut-sei=宮下
kn-aut-mei=雄博
aut-affil-num=4
ORCID=

en-aut-name=OkazakiMorihiro
en-aut-sei=Okazaki
en-aut-mei=Morihiro
kn-aut-name=岡崎守宏
kn-aut-sei=岡崎
kn-aut-mei=守宏
aut-affil-num=5
ORCID=

en-aut-name=SasakiMotofumi
en-aut-sei=Sasaki
en-aut-mei=Motofumi
kn-aut-name=佐々木基史
kn-aut-sei=佐々木
kn-aut-mei=基史
aut-affil-num=6
ORCID=

en-aut-name=HayakawaNobuhiko
en-aut-sei=Hayakawa
en-aut-mei=Nobuhiko
kn-aut-name=早川信彦
kn-aut-sei=早川
kn-aut-mei=信彦
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=岡山赤十字病院　総合内科

affil-num=2
en-affil=
kn-affil=岡山赤十字病院　総合内科

affil-num=3
en-affil=
kn-affil=岡山赤十字病院　総合内科

affil-num=4
en-affil=
kn-affil=岡山赤十字病院　総合内科

affil-num=5
en-affil=
kn-affil=岡山赤十字病院　総合内科

affil-num=6
en-affil=
kn-affil=岡山赤十字病院　糖尿病・内分泌内科

affil-num=7
en-affil=
kn-affil=岡山赤十字病院　糖尿病・内分泌内科
en-keyword=FDG-PET/CT
kn-keyword=FDG-PET/CT
en-keyword=大動脈炎症候群 (arteritis syndrome)
kn-keyword=大動脈炎症候群 (arteritis syndrome)
en-keyword=Takayasu's arteritis
kn-keyword=Takayasu's arteritis
END

start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=11
article-no=
start-page=2926
end-page=2951
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1934
dt-pub=19341130
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=?ber den Einflusse vegetativer Nerven auf den Kohlenhydratstoffwechsel. (II. Mitteilung.) ?ber den Einfluss des Parasympathicus auf den Kohlenhydratstoffwechsel.
kn-title=植物性神經ノ含水炭素新陳代謝ニ及ボス影響ニ就テ（第2報）副交感神經ノ含水炭素新陳代謝ニ及ボス影響ニ就テ
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Obwohl schon viele Forscher den Einfluss des Parasympathicus auf den Kohlenhydratstoffwechsel untersucht haben, so sind sie bisher doch noch nicht zu einem einheitlichen Resultat gekommen.
Nach der Iujektion von Pilocarpin und Atropin oder nach dem in der Bauchhohle ausgefuhrten abschneiden eines einseitigen N. vagus injizierte ich gesunden Hunden Traubenzucker in die Vena und Kam dabei zu folgenden Resultaten: 1) Injektion von Pilocarpin. Dabei wird die Senkung der Hyperglyk?mie nach der Injektion des Traubenzuckers 60 Minuten lang ein wenig gef?rdert, doch zeigt der Blutzucker nach Verlauf dieser Zeit keine Ver?nderung. Das Leberglykogen vermehrt sich gegen?ber einer Kontrolle, doch erf?hrt das Muskelglykogen keine quantitative Veranderung. 2) Injektiou von Atropin. Dabei senkt sich die nach der Injektion des Traubenzuckers erscheinende Hyperglyk?mie langsam. Das Leber- und Muskelglykogen vermindert sich auffallend. 3) Abschneiden eines einseitigen N. vagus. Dabei senkt sich die nach der Injektion des Traubenzuckers erscheinende Hyperglyk?mie ziemlich langsam. Das Leberglykogen vermiudert sich mehr als bei eiuer Kontrolle, aber das Muskelglykogenzeigt gegnuber einer Kontrolle keinen Unterschied.
en-copyright=
kn-copyright=

en-aut-name=FujiiM.
en-aut-sei=Fujii
en-aut-mei=M.
kn-aut-name=藤井昌展
kn-aut-sei=藤井
kn-aut-mei=昌展
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學石山外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=10
article-no=
start-page=2609
end-page=2644
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1934
dt-pub=19341031
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=?ber den Einfl?sse vegetativer Nerven auf den Kohlenhydratstoffwechsel. (I. Mitteilung.) ?ber den Einfl?ss des N. sympathicus auf den Kohlenhydratstoffwechsel.
kn-title=植物性神經ノ含水炭素新陳代謝ニ及ボス影響ニ就テ（第1報）交感神經ノ含水炭素新陳代謝ニ及ボス影響ニ就テ
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Die meisten Kliniker injizieren gern Traubenzucker, um die Funktion des Herzens zu verst?rken, Gift abzutreiben, Nahrung zu vermitteln oder Wasser in den mensch lichen K?rper einzuf?hren. Es ist von vielen Forschern versichert worden, dasz Traubenzucker nach seiner intraven?sen Injektion in Kurzer Zeit in den Venen unerkennbar wird. Da es auch unverkennbar ist, dasz dabei die innere Sekretionen verrichtenden Organe eine Rolle spielen, so untersuchte ich, welche Einfl?sse die vegetativen Nerven, die jene Organe verwalten, auf die im k?rper erscheinende Anh?ufung des Traubenzuckers aus?ben. Zuerst stellte ich fest wie sich bei und nach der intraven?sen Injektion von Traubenzucker Blutzucker, Harnzucker, Muskel-und Leberglykogen verhalten. Dann injizierte ich, um das Verhaltnis zwischen dem Sympathicus und dem Kohlenhydratstoffwechsel klar zu machen, Adrenalin und Yohimbin in gesunde Hunde, oder schnitt einen einseitigen N. splanchnicus ab und bestimmte bei denselben Hunden nach der Injektion des Traubenzuckers die Menge des Blutzuckers und des Leber-und Muskelglykogens. Bei den obigen Experimenten kam ich zu folgenden Ergebnissen. 1) 60 bis 90 minuten nach der intraven?sen Injektion des Traubenzuckers erscheint mit Sicherheit die vorl?ufige Hypoglyk?mie. 2) Wenn der Blutzucker nach der intraven?sen Injektion des Traubenzuckers ?ber 0.3% hinaufgeht, so vermehrt sich der Harnzucker auffallend; der Harnzucker findet sich aber in nur ganz geringer Menge, wenn der Blutzucker unter 0.14% bleibt. 3) Injektion von Adrenalin. Dabei zeigt die durch die Injektion des Traubenzuckers hervorgebrachte Hyperglyk?mie eine langsame Senkung, doch vermindert sich das Leber-und Muskelglykogen auffallend. 4) Injektion von Yohimbin. Dabei wird die Senkung dieser Hyperglyk?mie gef?rdert. Das Leberglykogen vermehrt sich jedoch gegen?ber einer Kontrolle, das Muskelglykogen vermindert sich gegen?ber einer Kontrolle etwas, aber nicht so auffallend. 5) Abschneiden eines einseitigen N. splanchnicus. Dabei wird die Senkung dieser Hyperglykamie ein wenig gef?rdert, die Hypoglyk?mie ist bedeutender als vor dem Abschneiden und dauert l?nger. Das Leberglykogen vermehrt sich gegen?ber einer Kontrolle und das Muskelglykogen vermindert sich gegen?ber einer Kontrolle, aber nicht so heftig.
en-copyright=
kn-copyright=

en-aut-name=FujiiM.
en-aut-sei=Fujii
en-aut-mei=M.
kn-aut-name=藤井昌展
kn-aut-sei=藤井
kn-aut-mei=昌展
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學石山外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=47
cd-vols=
no-issue=11
article-no=
start-page=2946
end-page=2972
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1935
dt-pub=19351130
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=?ber den Einfluss der Milz auf den Kohlenhydratstoflwechsel (Ein experimenteller Versuch)
kn-title=脾臟ノ含水炭素新陳代謝ニ及ボス影響ニ就テ（實驗的研究）
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Das Verh?ltnis der Milz zum Kohlenhydratstoffwechsel ist bisher zwar von vielen Forschern untersucht und ziemlich gekl?rt worden; man findet aber, wenn man jedes einzelne Versuchsresultat genau betrachtet, widersprechendes unter denjenigen Resultaten, die man unter denselben Versuchsbedingungen erreicht, und dazu herrscht noch eine Unklarheit dar?ber Bestandteil des Hormons der Milz auf den Kohlenhydratstoffwechsel einwirkt. Infolgedessen stellte ich mit gesunden Hunden verschiedenartige Experimente an, um obenerw?hnte Probleme zu l?sen, und kam zu folgenden Ergebnissen. 1) Milzexstirpation. Dabei senkt sich die nach der Injektion des Traubenzuckers erscheinende Hyperglyk?mie langsam. Das Leberglykogen vermindert sich mehr als bei einer Kontrolle, aber des Muskelglykogen zeigt gegen?ber einer Kontrolle keinen Unterschied. Der histologische Befund stimmt mit durch chemische Mittel erreichten Versuchsresultaten ?berein. 2) Injektion von Milzextrakt. Dabei wird die Senkung dieser Hyperglyk?mie gef?rdert. Das Leberglykogen vermehrt sich gegen?ber einer Kontrolle, doch erf?hrt das Muskelglykogen keine quantitative Ver?nderung. Der histologische Befund stimmt mit durch chemische Mittel erreichten Versuchsresultaten ?berein. 3) Injektion von Cholin. Dabei wird die Senkung dieser Hyperglyk?mie gef?dert. Das Leberglykogen vermehrt sich gegen?ber einer Kontrolle, aber das Muskelglykogen zeigt gegen?ber einer Kontrolle keinen Unterschied. Der histologische Befund stimmt mit durch chemische Mittel erreichten Versuchsresultaten ?berein. 4) In Milzextrakt ist eine cholinartige Substanz enthalten, welche auf den Kohlenhydratstoffwechsel f?rdernd einwirkt.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasanobu
en-aut-sei=Fujii
en-aut-mei=Masanobu
kn-aut-name=藤井昌展
kn-aut-sei=藤井
kn-aut-mei=昌展
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學石山外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=47
cd-vols=
no-issue=10
article-no=
start-page=2655
end-page=2673
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1935
dt-pub=19351031
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=?ber den Einflusse vegetativer Nerven auf den Kohlenhydratstoffwechsel (III. Mitteilung.) Der histologische Befund des Leber- und Muskelglykogen
kn-title=植物性神經ノ含水炭素新陳代謝ニ及ボス影響ニ就テ（第3報）肝臟竝ニ筋肉ノ組織學的所見
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Ich untersuchte histologisch Leber-und Muskelglykogen bei einem Hunde, dem man nach der Injektion von Adrenalin oder nach der Abschneidung eines einseitigen N. Splachnicus oder Vagus Traubenzucker injizierte, und erreichte dabei genau dieselben Resultate wie bei den in der 1. und 2. Mitteilung berichteten Versuchen, wo ich mich eines chemischen Mittels bediente.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasanobu
en-aut-sei=Fujii
en-aut-mei=Masanobu
kn-aut-name=藤井昌展
kn-aut-sei=藤井
kn-aut-mei=昌展
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學石山外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=50
cd-vols=
no-issue=3
article-no=
start-page=745
end-page=754
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1938
dt-pub=19380331
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Uber das sog. stri?re Blutsyndrom
kn-title=所謂線状體血液症候ニ就テ
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Im Jahre 1923 beobachteteu Sato und Yoshimatsu ein eigenartiges Blutbild bei zwei F?llen von akuter Encephalitis epidemica, d.h. w?hrend die Oxydasereaktiou nach Winkler und Schultze positiv siud, war die Peroxydasereaktion nach Sato uud Sekiya (Kupfervitriollosung, danu Benzidin und H(2)O(2)) in den rnyeloischeu Leukozyten des str?menden Blutes negativ. In weiteren Versuchen mit Sch?digung des Striatum von Kaninchen konnten sie das gleiche Blutbild hervorrufeu (sog. Peroxydasestich). Deshalb kam Sato nun auf die Vermutung, dass es sich bei diesem Blutsyndrom um Funktionest?ungeu des Striatum irn Hirustamm handelu k?nnte, und nannte dieses Ph?nomen "stri?res Blutsyndrom". Sie stellten dieses Blutsyndrom nur auf der H?he des Krankheitsstadiums fest; bei Besserung des Krankheitsprozesses verschwand es wieder. Aus diesem Grunde machte Sato eiuen Vorschlag, dieses stri?re Blutsyndrom auf die kliuische Herddiagnose des Hirns und die Prognosenbestimmung des Krankheitsprozesses anzuwenden. Hierauf untersuchten wir 83 Patienten mit akuter Encephalitis epidemica in verschiedenen Krankheitsstadieu, 16 P. mit Extrapyramidalsystemerkraukungen, 56 P. mit andereu akuten uud chroniechen Erkrankungen und Tiere nach Zerst?rung des Striatum auf des sog. stri?re Blutsyndrom, fanden es aber niemals.
Aus diesen Uutersuchungen kameu wir zun folgenden Schluss : Das sog. stri?re Blutsyudrom uach Sato und Yoshimatsu ist f?r klinische Lokalisationsdiagnose des Hirns und Prognosenbestimmungen des Kraukheitsprozesses ungeeignet.
en-copyright=
kn-copyright=

en-aut-name=NakataFujio
en-aut-sei=Nakata
en-aut-mei=Fujio
kn-aut-name=中田富士男
kn-aut-sei=中田
kn-aut-mei=富士男
aut-affil-num=1
ORCID=

en-aut-name=FujiiToshio
en-aut-sei=Fujii
en-aut-mei=Toshio
kn-aut-name=藤井敏夫
kn-aut-sei=藤井
kn-aut-mei=敏夫
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學柿沼，北山内科教室

affil-num=2
en-affil=
kn-affil=岡山醫科大學柿沼，北山内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=51
cd-vols=
no-issue=6
article-no=
start-page=1386
end-page=1397
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1939
dt-pub=19390630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=?ber 2 F ?ille von Mischinfektion von typh?ser Erkrankung und Dysenterle
kn-title=Paratyphus=Bト赤痢トノ混合感染症例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Das Zusammeutreffen von Typhus abdominalis bzw. Paratyphus mit Dysenterie wird nur selten beobachiet. Im Japan sind bis heute im ganzen 10 solcher F?lle mitgeteilt worden. Wir hatten im Sommer 1937 in unserem Hospital Gelegenheit, 2 solcher F?lle zu beobachten. Der erste Fall war eine Mischinfektion von Paratyphus-B und Dysenterie bei einem 23 j?hrigen Mann, der mit Verdacht auf Dysenterie in unserem Hospital aufgenommen worden war. Der Pat. zeigte starke Hirnsymptome und Leukopenie, nebeu aubaltendem Fieber und heftiger Diarrh?e, die jedoch erst am dritteu Kraukheitstage auftrat. Auf grund dieser symptome haben wir ein Zusammentreffen von typh?ser Krankheit mit Dysenterie angenommen und wiosen in der Tat Kawase'sche Dysenteriebazillen im Stuhl und Paratyphus-B-bazillen im Blut nach. Der Pat. erlag rasch trotz aller symptomatischen Behandlung der schweren Symptome. Zweiter Fall: Bei einem 12 j?hrigen Knaben, der wegen Typhus abdominalis im unserer Behandlung stand, zeigten sich pl?tzlich w?hrend seiner Rekonvaleszenz dysenterische Symptome, wie Diarrboe mit Tenesmus, Dr?ckempfindlichkeit am als Strang f?hlbdren S-Romanum usw. Wir konnten nicht nur aus dem Kot Dysenteriebazillen (Komagome-B) isolieren, sondern es wurden nach Hauptagglutinine gegen Dysenterieund Typhusbazillen im Krankenserum nacbgewiesen und damit Dysenterie als seltene Komplikation im Verlaufe des Typhus abdominalis festgestellt. Es war bei diesen Kuaben bald Besserung eingetraten.
en-copyright=
kn-copyright=

en-aut-name=SakanakaTadaiti
en-aut-sei=Sakanaka
en-aut-mei=Tadaiti
kn-aut-name=坂中只一
kn-aut-sei=坂中
kn-aut-mei=只一
aut-affil-num=1
ORCID=

en-aut-name=HuziiTosio
en-aut-sei=Huzii
en-aut-mei=Tosio
kn-aut-name=藤井敏夫
kn-aut-sei=藤井
kn-aut-mei=敏夫
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學北山内科教室

affil-num=2
en-affil=
kn-affil=岡山市立岡山病院
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=12
article-no=
start-page=2488
end-page=2505
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1941
dt-pub=19411231
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Morphogonetische Studien ?ber das Geruchsorgan uud. das Jacobsonsche Organ bei dem der Okayama Provinz eigent?mlichen Hynobius
kn-title=岡山縣産HynobiuSニ於ケル嗅器竝ニJacobson'sches Organノ發生學的研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Das Geruchsorgan der Amphibien ist seit alters her ontogenetisch Gegenstand lebhafter Er?rterungen gewesen. Dieses Organ ist jedoch, wie allgemein wohl bekannt, je nach dem einzelnen Organismus mehr oder minder anders gestaltet. Der verf. hat nun bei Hynobius, das im Bezirk von Okayama-ken allein zu treffen ist, das Geruchsorgan vom ntogenetischen Standpunkt ans systematisch untersucht. Dabei benutzte er 12 Embryo nen des Hynobius, deren K?rperlange von 6.5mm ab bis zn 71, 0mm betrug. Die Ergebnisse waren wie folgt. 1) Bei Hynobius tritt die erste Anlage des Geruchsorganes bei einem Embryo von 9,5mm K?rperl?nge auf, und zwar als eine teilweise Verdickung des Ektodermas, welches. vom Gehirnsack verl?uft. 2) Die Enstehung der Geruchsplatte beruht auf der Verdickung der Schicht der Organa sensuum; die ?usserste Schicht des Ektodermas stehb mit dieser Entstehung in keiner Beziehung. 3) Bei der Geruchsplatte erfolgt sodann eine Einsenkung, die in einer von der Mitte etwas kaudalwarts entfernten Stelle stattfindet. Durch diese Einsenkung entsteht die Foveola olfactorius. 4) Die Foveola olfactorius bildet bei einem Embryo von 8,5mm K?rperl?nge das S?ckchen der Nase aus. Die erste Anlage der Nasenh?hle wird bei einem Embryo von 9,0 mm K?rperl?nge beobachtet. 5) Durch die Differenzierung der Wand des Nasens?ckchens wird auf der Lumenoberfl?che der Organa sensuum eine durchsichtige Schicht gebildet. Bei weiterer Entwicklung geschicht eine Organisation an der Wand des Nasens?ckchens, wodurch mehrere W?lbungen an derselben Wand entstehen. 6) Die erste Anlage des Ausf?hrungsganges ist bei einem Embryo von 15,0mm K?rperl?nge erkennbar. Bei. einem Embryo von 40,5mm K?rperlange scheint sie verschwunden zu sein, nachdem sie sehr kurz geworden war. 7) Das Jacobsonsche Organ des Hynobius bringt bei einem Embryo von 20, 0mm K?rperl?nge seine erste Anlage zum Vorschein, welche wie das Divertikel der Nasenh?hle aussieht. Die Jacobsonsche sowie die Bowmansche Druse treten erst bei einem Embryo von 25,0mm Korperlange in die Erscheinung: die beiden stellen tubulare Dr?sen dar. 8) Bei einem Embryo von 12,5mm K?rperl?nge treibt das Nasensackchen aus seinem kaudalen Ende eine Epithelknospe. Dieser Knospe entgegen schickt das Epithel der Mundhohle einen Empfangshugel zur Verbindung mit der Knospe aus. Bei einem Embryo von 16,0mm K?rperl?uge sind die Epithelkan?lchen durchbrochen, wodurch die Anlage des hinteren Nasenlochs gebildet wird., 9) Bei einem Embryo von 20,0mm K?rperl?nge treten an dei Innenwand des hinteren Nasenlochs klappenartige Falten auf, welche indes bei einem Embryo von 40,5mm K?rperl?nge spurlos verschwinden. 10) Die Anlage des Tr?nenkanals tritt bei einem Embryo von 25, 0mm K?rperl?nge in die Erscheinung. Sie gelangt bei einem Embryo von 27, 0mm K?rperl?nge als ein Tr?nenkanal fast zur vollen Entwicklung.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasakazu
en-aut-sei=Fujii
en-aut-mei=Masakazu
kn-aut-name=藤井正和
kn-aut-sei=藤井
kn-aut-mei=正和
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學解剖學教室胎生學研究室
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=11
article-no=
start-page=2248
end-page=2262
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1941
dt-pub=19411130
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Morphogenetische Studien ?ber das Jacobsonsche Organ bei S?ugetieren. IV. Mitteilung. Untersnchungen bei Embryonen von Kaninchen
kn-title=哺乳動物ノJacobson'sches Organノ形態學的發生ニ關スル研究（其ノ4）（殊ニ家兎胎兒ニ於ケル檢索）
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Fernerhin hat der Verf. bei Embryonen von Kaninchen, welche sich in 9 Entwicklungsstudien von 6,0mm Sch. -St. -L. befunden, die Entwicklungsvorgange des Jacobsonschen Organes systematisch und morphogenetisch untersucht. Aus dem Vergleich der Ergebnisse mit den Vorhergehenden drei Ergebnissen kam der Verf. zu folgendem Schluss: 1) Die erste Anlage des Jacobsonschen Organes wird bei einem Embryo von 6,0mm Sch. -St. -L. beobachtet. Sie ist zun?chst als eine Verdickung des Epithels, welches an einem ?bergangsteil der Innenwand des Sulcus Olfactorius zur Oberhaut vorhanden ist, angedeutet. Hierauf folgt dann die Einsenkung des mittleren Teiles der verdickten Partie. 2) Das Lumen entsteht dadurch, dass sich die beiden Seiten der eingesunkenen Furche dammartig erbeben und dann vom kaudalen Ende der Anlage her allm?hlich oral- w?rts eingeschn?rt und von der Wand der Nasenh?hle abgetrennt werden. 3) Die Differenzierung der Lumenwand beginnt bei einem Embryo von 8,5mm Sch. -St. -L. Die ventral Innenwand ist dick, w?hrend die dorsale Aussenwand d?nn ist, an der auch keine Furche anzutreffen ist. 4) Das Jacobsonsche Organ der Embryonen von Kaninchen m?ndet durch einen rundlichen Ausf?hrungsgang in die Innenwand der Nasenh?hle, und zwar am oralen Ende der Innenwand in der N?he des Bodens der Nasenh?hle. 5) Die Nebendr?se bringt zuerst ihre dorsale Dr?se bei einem Embryo von 20,0mm Sch. -St. -L. zum Vorschein. Darauf tritt dann die Enddr?se bei einem Embryo von 26,0 mm Sch. -St. -L. in die Erscheinung. 6) Der Jacobsonsche Knorpel ist zum erstenmal bei einem Embryo von 2,0mm Sch. -St. -L. erkennbar. Er entwickelt sich dann bei einem Embryo von 20,0mm Sch. -St. -L. sehr rasch, nimmt eine Hufeisenform an und umhullt das Jacobsonsche Organ ausschliesslich eines Teiles der dorsalen Partie.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasakazu
en-aut-sei=Fujii
en-aut-mei=Masakazu
kn-aut-name=藤井正和
kn-aut-sei=藤井
kn-aut-mei=正和
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學解剖學教室胎生學研究室
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=10
article-no=
start-page=2082
end-page=2094
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1941
dt-pub=19411031
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Morphogenetische Studien ?ber das Jacobsonsche Organ bei S?ugetieren. III. Mitteilung. Untersuchungen bei Embryonen von Meerschweinchen
kn-title=哺乳動物ノJacobson'sches Organノ形態學的發生ニ關スル研究（其ノ3）Meerschweinchenembryonenニ於ケル檢索
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In dieser Abteilung hat der Verf. die Entwicklung des Jacobsonschen Organes bei 8 Embryonen der Meerschweinchen von 7, 0mm ab bis zu 56, 0mm Sch. -St. -L. systematisch und morphogenetisch untersucht. Aus dem Vergleich der Ergebnisse mit den vorherge. henden kam er zu folgendem, Schlues: 1) Bei Embryonen von Meerschweinchen ist die erste Spur des Jacobsonschen Organes als eine Divertikelbildung an der medialen Wand des Sulcus Olfactorius bei einem Embryo von 7, 0mm Sch. -St. -L. angedentet. Beim Auftritt dieser Anlage nimmt die mediale Wand mehr oder weniger an Dicke zu. 2) Das Lumen des Jacobsonschen Organes tritt bei einem Embryo von 8,0mm Sch. -St. -L. zun?chst am kaudalen Ende des Embryos auf und entwickelt sich dann allmahlich oralw?rte hin. 3) Die Differenzierung der Lumenwand findet schon bei einem Embryo von 10,5mm Sch. -St. -L. statt. In diesem Stadium ist die dorsale Innenwand des Lumens dick, w?h- rend die ventrale Aussenwand des Lumens eine ausserordentlich d?nne ist. 4) Erst bei einem Embryo von 11,0mm Sch. -St. -L. wird eine Furche auf der Aussenwand beobachtet. 5) Das Lumen des Jacobsonschen Organes gelangt bei einem Embryo von 15,0mm Sch. -St. -L. zur vollen Entwicklung. 6) Bei Embryonen von Meerschweinchen kommt die Enddr?se am fr?hesten zum Vorschein. Ihre erste Spur ist bei einem Embryo von 17, 0mm Sch. -St. -L. erkennbar. Etwas ep?ter tritt die ventrale Dr?se in die Erscheinung, am sp?testen die dorsale Dr?se. 7) Die dorsale Innenwand des Lumens besteht aus einem mehrschichtigen Zylinderepithel. Die ventrale Aussenwand ist mit einem d?nnen, einoder zweischichtigen. Zylinderepithel ?berzogen. Die Nebendr?se h?ngt kontinuierlich mit dem Grenzteile der beiden Dr?sen zusammen und kommuniziert mit ihnen.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasakazu
en-aut-sei=Fujii
en-aut-mei=Masakazu
kn-aut-name=藤井正和
kn-aut-sei=藤井
kn-aut-mei=正和
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學解剖學教室胎生學研究室
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=9
article-no=
start-page=1834
end-page=1848
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1941
dt-pub=19410930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Morphogenetische Studien ?ber das Jacobsonsche Organ bei S?ugetieren. II. Mitteilung Untersuchungen bei M?usen
kn-title=哺乳動物ノJacobson'sches Organノ形態學的發生ニ關スル研究（其ノ2）Mus molosseimusニ於ケル檢索
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Im Anschluss an den vorhergehenden Bericht hat der Verf. in dieser Abteilung bei 10 Embryonen von Mus molosseimus von 4,0mm an bis zu 25,0mm Sch. -St. -L. (d. h. bis zum Alter von einem Tag nach der Geburt) das Jacobsonsche Organ morphogenetisch untersucht und kam zu folgendem Schluss: 1) Bei diesen M?usen wird das erste Anzeichen des Jacobsonschen Organes bei einem Embryo von 4,0mm Sch. -St. -L. als eine Verdickung der lateralen Wand der Nasenh?hle angedeutet. In die verdickte Partie hinein sinkt sodann das innere Lumen des Sulcus olfactroius ein und bildet dadurch die erste Anlage des inneren Lumens des Jacobsonschen Organes. 2) Der Schlauch des Jacobsonschen Organes bildet sich aus der Anlage des betr. Organes, indem die Anlage, gerade wie bei der Ratte, vom kaudalen Ende her nach dem kranialen Teile hin allm?hlich eingeschn?rt und schliesslich von der Wand des Sulcus olfactorius abgetrennt wird. 3) Das Jacobsonsche Organ der M?use sieht wie ein St?bchen aus. An beiden Seiten des Cartilago septi nasi verl?uft es entlang der K?rperachse in kaudal-kranialer Richtung fast propotional zur inneren Seitenwand der Nasenh?hle, und zwar an der Mitte der dorsoventralen Linie der Seitenwand. Das kraniale Ende des Organes ?ffnet sich durch einen engen Ausfuhr?ngsgang am kranialen Ende der inneren Wand der Nasenh?hle. Das kaudale Ende des Organes l?uft in ein Blindende ungefahr an der Mitte kranial-kaudalw?rts verlaufender Linie der Nasenh?hle aus. 4) Das Jacobsonsche Organ dreht sich, gerade wie bei der Ratte, ein wenig um seine eigene L?ngsachse. Die L?ngsfurche, welche auf der Aussenwand des Organes in die Erscheinung tritt, bringt ihre erste Spur schon bei einem Embryo von 6,2mm Sch. -St. -L. zum Vorschein. Mit der Entwicklung des Embryos nimmt sie an Tiefe zu. 5) Bei einem Embryo von 14,2mm Sch. -St. -L. werden die Anlage der Enddr?se und die der dorsoventralen Glandula erkennbar. Die Anlage der ventralen Glandula tritt etwas sp?ter auf. 6) Das Epithel der Schlauchwand ist am d?nnen Teile der ?usseren Furche von einem d?nnen Respirationsepithel umhult, die innere Wand des Schlauches ist mit einem dicken Geruchsepithel ?berzogen. 7) Bei Emgryonen von Mausen ist die Enddr?se am besten ausgebildet.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasakazu
en-aut-sei=Fujii
en-aut-mei=Masakazu
kn-aut-name=藤井正和
kn-aut-sei=藤井
kn-aut-mei=正和
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學解剖學教室胎生學研究室
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=8
article-no=
start-page=1547
end-page=1560
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1941
dt-pub=19410831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Morphogenetische Studien ?ber das Jacobsonsche Organ bei S?ugetieren
kn-title=哺乳動物ノJacobson'sches Organノ形態學的發生ニ關スル研究（其ノ1）（Rattus albusニ於ケル檢索）
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Das Jacobsonsche Organ ist ein Nasenorgan, das am Boden der Nasenh?hle, zu beiden Seiten der Scheidewand gelegen ist. Seitdem es im Jahre 1811 von dem d?nischen Gelehrten Jacobson zum erstenmal entdeckt und von ihm selbst unter der Bezeichnung "Organo vomeronsale Jacobsoni" bekannt gegeben worden war, erregte es eine allgemeine Aufmerksamkeit und hat eine kaum mehr zu ?berschauende F?lle von Arbeiten in die ?ffentlichkeit bef?rdert. Als die bekanntesten unter den Forschern sind Namen zu nennen wie Roserthal (1826), Balogh (1860), Dursy (1869), Klein (1882), Harvey-Reuden (1882), L?we (1888), Herzbeld (1888), Range (1893), Garnault (1895), R?se (1893), Mihalkovics (1868), Broman (1920), Navratil (1926) u.a.m. Trotzdem konnte der Verf. in der Literatur, soweit sie ihm zug?nglich war, keinen Bericht finden, der in die Funktion dieser Organe klare Einsicht gew?hrte. Broman n?mlich hat auf Grund der Ergebnisse seine Tierexperimente die Behauptung aufgestellt, dass dieses Organ ein Wassergeruchsorgan darstelle, Navratil konnte trotz seiner ausgedehntesten Studien noch koine bindende Erkl?rung bez?glich der physiologischen Funktion dieses Organes geben. Wenn man einmal an die Enge des Ausfuhrungsganges dieses Organes denkt, erscheint es kaum m?glich, dass die Luft und irgendein Geruch durch diesen engen Gang hindurch zum betr. Organ gelangen. Man kann jedoch dabei auch die M?glichkeit nicht in Abrede. stellen, dass sich im lebenden Organismus das Organ gelegentlich mehr oder weniger erweitert. Die Annahme, welche das einschl?gige Organ f?r ein Geruchsorgan h?lt, darf man deshalb nicht ganz von der Hand weisen. Um das Wesen dieses funktionell noch nicht v?llig aufgekl?rten Organes festzustellen, ist es erforderlich, histologisch-anatomische Untersuchungen, wie unsere V?rganger getan haben, gr?ndlich auszuf?hren. Aber es ist auch ohne wciteres klar, dass eine systematisch angeordnete morphogenetische Vergleichsuntersuchung ?ber das in Rede stehende Organ sicher zur Aufkl?rung seines Wesens vieles beitragen kann. Diese morphogenetische Untersuchung erschien dem Verf. um so interessanter, weil er in der bisherigen sowohl japanischen als auch europ?ischen Literatur keinen Bericht finden konnte. Zur Untersuchung w?hlte er S?ugetiere, von denen er zun?chst 10 Embryonen von Ratten von 6, 2mm an bis zu 36, 0mm Sch -St. -L. benutzte und kam zu folgendem Schluss: 1) Das Jacobsonsche Organ von Ratten ist bei einem Embryo von 6, 2mm Sch. -St.-L. als die erste Spur angedeutet, und zwar in der Gestalt von einer kleinen halbkugligen Ausbuchtung in der Mitte der inneren Seitenwand des Sulcus olfactorius. Diese Ausbuchtung entwickelt sich allm?hlich und wird schliesslich zu einer L?ngsfurche, die entlang an der L?ngsachse des Sulcus olfactorius liegt. 2) Die vertikale Furche wird vom kaudalen Ende her allmahlich eingeschn?rt, bildet sich dann bei eiuem Embryo von 10, 2mm Sch, -St. -L. zu einem Lumen, dessen Blindende kaudalw?rts gerichtet ist. Das kraniale Ende dieses Lumen ?ffnet sich am kranialen Ende der Innenwand, welches nahe am Boden der Nasenh?hle liegt. 3) Mit der weiteren Entwicklung des Embryos wird an der ?usseren Seite des Lumens eine L?ngsfurche gebildet, indem die Aussenwand des Lumens in dasselbe hineinsinkt. Das Lumen selbst dreht sich dabei allm?hlich um die L?ngsachse. 4) Das Epithel der Lumenwand besteht in fr?heren Stadium aus mehrschichtigem Zylinderepithel, welehes dem Epithel der Nasenh?hle an Beschaffenheit und Dicke gleich ist.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasakazu
en-aut-sei=Fujii
en-aut-mei=Masakazu
kn-aut-name=藤井正和
kn-aut-sei=藤井
kn-aut-mei=正和
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學解剖學教室胎生學研究室
END

start-ver=1.4
cd-journal=joma
no-vol=61
cd-vols=
no-issue=3
article-no=
start-page=57
end-page=60
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1949
dt-pub=19490430
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=急性「バリウム」中毒の1例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=平木潔
kn-aut-sei=平木
kn-aut-mei=潔
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井千秋
kn-aut-sei=藤井
kn-aut-mei=千秋
aut-affil-num=2
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=淵本昭
kn-aut-sei=淵本
kn-aut-mei=昭
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山醫科大學北山内科教室

affil-num=2
en-affil=
kn-affil=岡山醫科大學北山内科教室

affil-num=3
en-affil=
kn-affil=岡山醫科大學北山内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=64
cd-vols=
no-issue=4
article-no=
start-page=645
end-page=654
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1952
dt-pub=19520430
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=ビリルビンの腸管内吸收に関する実驗的研究 第三篇 腸管内直接ビリルビンの間接化に関する検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井弘吉
kn-aut-sei=藤井
kn-aut-mei=弘吉
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山医科大学第一内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=64
cd-vols=
no-issue=4
article-no=
start-page=639
end-page=645
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1952
dt-pub=19520430
dt-online=
en-article=
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en-subject=
kn-subject=
en-title=
kn-title=ビリルビンの腸管内吸收に関する実驗的研究 第二篇 ビリルビンの腸管内吸收部位に就て
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井弘吉
kn-aut-sei=藤井
kn-aut-mei=弘吉
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山医科大学第一内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=64
cd-vols=
no-issue=4
article-no=
start-page=627
end-page=638
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1952
dt-pub=19520430
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kn-subject=
en-title=
kn-title=ビリルビンの腸管内吸收に関する実驗的研究 第一篇 ビリルビンの腸管内吸收機転に就て
en-subtitle=
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kn-abstract=
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kn-copyright=

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kn-aut-name=藤井弘吉
kn-aut-sei=藤井
kn-aut-mei=弘吉
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ORCID=

affil-num=1
en-affil=
kn-affil=岡山医科大学第一内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=65
cd-vols=
no-issue=11
article-no=
start-page=1987
end-page=1999
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dt-accepted=
dt-pub-year=1953
dt-pub=19531130
dt-online=
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kn-subject=
en-title=
kn-title=梅毒における含水炭素代謝の研究 第3報 各期梅毒における血糖と血漿蛋白分屑
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井浩
kn-aut-sei=藤井
kn-aut-mei=浩
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室
END

start-ver=1.4
cd-journal=joma
no-vol=65
cd-vols=
no-issue=11
article-no=
start-page=1973
end-page=1986
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dt-accepted=
dt-pub-year=1953
dt-pub=19531130
dt-online=
en-article=
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kn-subject=
en-title=
kn-title=梅毒における含水炭素代謝の研究 第2報 駆梅療法による血糖の消長
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井浩
kn-aut-sei=藤井
kn-aut-mei=浩
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室
END

start-ver=1.4
cd-journal=joma
no-vol=65
cd-vols=
no-issue=11
article-no=
start-page=1949
end-page=1971
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dt-accepted=
dt-pub-year=1953
dt-pub=19531130
dt-online=
en-article=
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kn-subject=
en-title=
kn-title=梅毒における含水炭素代謝の研究（第1報）各期梅毒の遊離及び結合血糖量の消長について
en-subtitle=
kn-subtitle=
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kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井浩
kn-aut-sei=藤井
kn-aut-mei=浩
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室
END

start-ver=1.4
cd-journal=joma
no-vol=65
cd-vols=
no-issue=10
article-no=
start-page=1797
end-page=1801
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dt-accepted=
dt-pub-year=1953
dt-pub=19531031
dt-online=
en-article=
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kn-subject=
en-title=
kn-title=泌尿器結核に対するISCOTINの効果
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kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
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en-aut-mei=
kn-aut-name=根岸博
kn-aut-sei=根岸
kn-aut-mei=博
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井浩
kn-aut-sei=藤井
kn-aut-mei=浩
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室
END

start-ver=1.4
cd-journal=joma
no-vol=65
cd-vols=
no-issue=6
article-no=
start-page=789
end-page=792
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dt-accepted=
dt-pub-year=1953
dt-pub=19530630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=柵原鑛山に於ける珪肺症の研究 第II報 珪肺症患者に於ける心臟機能検査
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=淵本昭
kn-aut-sei=淵本
kn-aut-mei=昭
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井幸雄
kn-aut-sei=藤井
kn-aut-mei=幸雄
aut-affil-num=2
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=水田勝
kn-aut-sei=水田
kn-aut-mei=勝
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部

affil-num=2
en-affil=
kn-affil=岡山大学医学部

affil-num=3
en-affil=
kn-affil=岡山大学医学部
END

start-ver=1.4
cd-journal=joma
no-vol=65
cd-vols=
no-issue=6
article-no=
start-page=783
end-page=788
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dt-revised=
dt-accepted=
dt-pub-year=1953
dt-pub=19530630
dt-online=
en-article=
kn-article=
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kn-subject=
en-title=
kn-title=柵原鑛山に於ける珪肺症の研究 第I報 珪肺症患者の血液像並びに臨床像
en-subtitle=
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kn-copyright=

en-aut-name=
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kn-aut-name=淵本昭
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ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井幸雄
kn-aut-sei=藤井
kn-aut-mei=幸雄
aut-affil-num=2
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=白髪克也
kn-aut-sei=白髪
kn-aut-mei=克也
aut-affil-num=3
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=水田勝
kn-aut-sei=水田
kn-aut-mei=勝
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部

affil-num=2
en-affil=
kn-affil=岡山大学医学部

affil-num=3
en-affil=
kn-affil=岡山大学医学部

affil-num=4
en-affil=
kn-affil=岡山大学医学部
END

start-ver=1.4
cd-journal=joma
no-vol=65
cd-vols=
no-issue=2
article-no=
start-page=309
end-page=322
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1953
dt-pub=19530228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=昭和22，23，24年度岡山縣下流行日本腦炎に関する統計的臨床観察
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井千秋
kn-aut-sei=藤井
kn-aut-mei=千秋
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部北山内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=65
cd-vols=
no-issue=2
article-no=
start-page=298
end-page=308
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1953
dt-pub=19530228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=ワクチン接種による岡山縣下の日本腦炎予防に就て
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井千秋
kn-aut-sei=藤井
kn-aut-mei=千秋
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部北山内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=65
cd-vols=
no-issue=2
article-no=
start-page=289
end-page=297
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1953
dt-pub=19530228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Phenosulfazoleに依る日本腦炎の治療及予防に関する実驗的研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井千秋
kn-aut-sei=藤井
kn-aut-mei=千秋
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部北山内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=66
cd-vols=
no-issue=7
article-no=
start-page=1495
end-page=1499
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1954
dt-pub=19540731
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=脳下垂体埋沒療法の効果並に副作用に関する研究 第1編 埋沒に有効な牛脳下垂体の研究並に埋沒療法の効果について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=石天之樞
kn-aut-sei=石天
kn-aut-mei=之樞
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=石泰三
kn-aut-sei=石
kn-aut-mei=泰三
aut-affil-num=2
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井政人
kn-aut-sei=藤井
kn-aut-mei=政人
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室
END

start-ver=1.4
cd-journal=joma
no-vol=66
cd-vols=
no-issue=7
article-no=
start-page=1489
end-page=1493
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1954
dt-pub=19540731
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on Total Vitamine C. content in skin 5th Chapter Injecting some Terramycin (intravenous) to a rabbit fed with vitamin-C-less food, I estimated Total V. C. content in blood and skin
kn-title=皮膚内総ビタミンCの研究 第5編 テラマイシン注射による血液内および皮膚内総ビタミンC量の消長について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1) By injecting Terramycin 20mg/kg intravenously, Total V. C. content within blood decreased 16.5% in an hour; after 2 hours' duration, experienced an increase of 8.9% on the contrary. Within skin, it has increased 8.2% in an hour, 28.4% in 2 hours; on the contrary, it has proved a decrease after 5 hours. 2) In case 60 mg/kg Terramycin has been intravenously injected, Total V. C. amount in blood kept on decreasing from 2 hours after, but returned to its normal state after 24 hours. In skin, it has also undergone a similar slight decrease, but has recovered to its normal state after 24 hours, without any noticeable influences.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasato
en-aut-sei=Fujii
en-aut-mei=Masato
kn-aut-name=藤井政人
kn-aut-sei=藤井
kn-aut-mei=政人
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室
END

start-ver=1.4
cd-journal=joma
no-vol=66
cd-vols=
no-issue=7
article-no=
start-page=1483
end-page=1487
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1954
dt-pub=19540731
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on Total Vtamine C content in skin. 4th Chapter Having injected some Chloromycetin in a rabbit fed with vitamine-C-less food, estimated Total V. C. content in blood as well as in skin
kn-title=皮膚内総ビタミンCの研究 第4編 クロロマイセチン注射による血液内および皮膚内総ビタミンC量の消長について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1) When 40mg/kg of Chloromycetin is injected, Total V.C. within blood indicated a decrease, still showing the same tendency even after 24 hours. In skin, after 2 hours, there happened an increase of 30.3%, but after 5 hours, decreased on the contrary. 2) When Chloromycetin 120 mg/kg has been injected, Total V.C. amount in blood decreased to an extent of 18.7% after two hours, but showed an increase of 21.7% after 5 hours, and again proved a decrease of 27.1% after 10 hours. In skin, it has decreased ever since 2 hours. After 24 hours' lapse, Total V.C. amount within blood and skin has been recovered to its normal state.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasato
en-aut-sei=Fujii
en-aut-mei=Masato
kn-aut-name=藤井政人
kn-aut-sei=藤井
kn-aut-mei=政人
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室
END

start-ver=1.4
cd-journal=joma
no-vol=66
cd-vols=
no-issue=7
article-no=
start-page=1477
end-page=1482
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1954
dt-pub=19540731
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on Total Vitamine C content in skin. 3rd Chapter After having injected some Dihydro-Streptomycin sulfate in a rabbit fed with vitamine-C-less food, I tried to determine Total Vitamine C amount
kn-title=皮膚内総ビタミンCの研究 第3編 ストレプトマイシン注射による血液内および皮膚内総ビタミンC量の消長について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1) In case 20 mg/kg Streptomycin has been injected, Total V. C. content in blood indicated a decrease of 24.3% Within 2 hours, 44.0% increase after 5 hours on the contrary, but again a decrease happened after 10 hours. The changes that occurred to Total V. C. in skin proved a decrease of 6.2% in 2 hours, 22.8% in 5 hours, but in 10 hours, indicated an increase on the contrary. 2) In case 60 mg/kg Streptomycin has been injected, Total V. C. content within blood proved a decrease in 2 hours, but on the contrary, an increase of 22.5% in 10 hours; after 24 hours, itagain showed a decrease. Total V. C. content within skin kept on decreasing since 2 hours.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasato
en-aut-sei=Fujii
en-aut-mei=Masato
kn-aut-name=藤井政人
kn-aut-sei=藤井
kn-aut-mei=政人
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室
END

start-ver=1.4
cd-journal=joma
no-vol=66
cd-vols=
no-issue=7
article-no=
start-page=1469
end-page=1475
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1954
dt-pub=19540731
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on Total Vitamine C content in skin 2nd Chapter By injecting 20, 000 unit/kg amount of crystal Penicillin K in a rabbit fed with vitamine-C-less food, I tried to determine the Total V. C. quantity in the blood and skin
kn-title=皮膚内総ビタミンCの研究 第2編 結晶ペニシリンK注射による血液内および皮膚内総ビタミンC量の消長について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1) In half an hour after the injection of Penicillin, Total V. C. in blood proved an increase, which after 5 hours, reached 102.6% at the highest, and showed still an increase after 24 hours. The Total V. C. amount in skin has risen to 21.9% in an hour after the injection. 81.0% at highest after an hour, and still indicated an increase even after 24 hours. 2) The increasing tendency occurred for total amount after the injection of Penicillin has proved to lower in the course of time, yet showed an increase even after 7 days' durati on. 3) By the injection of Penicillin, the rabbit fed with vitamine-C-less food had been stimulated its formating faculty of Vitamine C.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasato
en-aut-sei=Fujii
en-aut-mei=Masato
kn-aut-name=藤井政人
kn-aut-sei=藤井
kn-aut-mei=政人
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室
END

start-ver=1.4
cd-journal=joma
no-vol=66
cd-vols=
no-issue=7
article-no=
start-page=1461
end-page=1468
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1954
dt-pub=19540731
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on Total Vitamine C content in skin lst Chapter Total V. C. amount in the blood of a normal rabbit and in its skin, as well as on its changes due to pealing skin and picking blood
kn-title=皮膚内総ビタミンCの研究 第1編 正常家兎の血液内および皮膚内総ビタミンC量並にそれに対する採皮採血の影響について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1) I have conducted a V. C. determination in blood and skin of a rabbit, due to revised method adopted by Fujita & Ebihara. 2) The total V. C. content in the blood of a rabbit fed with vitamine-C-less food proved 6.51mg% at maximum, 1.39mg% at minimum, in average, 3.08mg%; 93% of total instances indicated between 2 and 5mg% 3) The Total V. C. content in the skin of a rabbit fed with vitamine-C-less food proved 12.79mg% at maximum, 1.52mg% at minimum, while, In average, proved to be 5.35mg% The 86.6% of total cases proved between 4 and 7mg% 4) The curve of changes due to lapse of time attributed to Total V. C. within blood and skin of a rabbit fed with vitamine-C-less food, when it has been pealed skin and picked blood, proved a glass-picture in a parallel state, as it indicated a slight increase for the estimated within blood, while, a slight decrease when estimated within skin; the ratio both of increase and decrease shown by this increase-decrease curve, is very small; and proved almost no influence on the V. C. amount due to pealing skin and picking blood. 5) The effect of such-like operations on Total V. C. metabolism within blood and skin, though slight in degree, continues for a considerable duration of time; besides, effects due to temperature, though slight too, is thought to occur to a certain extent.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasato
en-aut-sei=Fujii
en-aut-mei=Masato
kn-aut-name=藤井政人
kn-aut-sei=藤井
kn-aut-mei=政人
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室
END

start-ver=1.4
cd-journal=joma
no-vol=66
cd-vols=
no-issue=1
article-no=
start-page=31
end-page=36
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1954
dt-pub=19540131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=興味ある腸閉塞症の3例竝に完全内臟転錯症について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=成川俊光
kn-aut-sei=成川
kn-aut-mei=俊光
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井政人
kn-aut-sei=藤井
kn-aut-mei=政人
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室
END

start-ver=1.4
cd-journal=joma
no-vol=66
cd-vols=
no-issue=1
article-no=
start-page=27
end-page=30
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1954
dt-pub=19540131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=帯状疱疹の治療特にIrgapyrinの効果について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤井浩
kn-aut-sei=藤井
kn-aut-mei=浩
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部皮膚科泌尿器科教室
END

start-ver=1.4
cd-journal=joma
no-vol=67
cd-vols=
no-issue=1
article-no=
start-page=29
end-page=42
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1955
dt-pub=19550131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effect of the Bone-Marrow Autolysate on Medullary Hematopoiesis Part III: Experiment in adding the Autolysate to Bone-Marrow Tissue Culture
kn-title=骨髓自家融解液の骨髓造血に及ぼす影響 第3編 骨髄体外組織培養への添加実験
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The author, about the improvement of bone-marrow hematopoiesis, presumed in Part I that the blood vessel function might be one cause; in Part II, concluded that the reticuloendotherial system should be sound a prior, and as was told in the so-called "autohormone theory" it might be due to the particular hormone-like function which is proper to that extract. Accordingly, in this part, in order to exactly verify whether the bone-marrow extract would be influenced directly to the medullary parenchymal Hematopoiesis or not, the author added that extract to bone-marrow tissue culture and inspected its growth rate, wandering velosity, and changes in quantity of hemoglobin as well as in number of blood cells. First, taking observations of the growth rate of bone-marrow tissue, and the wandering velocity of intramedullary pseudoeosinocytes, under culture in cover slips, it was known that the addition of extract in a proper density improves remarkably the growth of tissue, and that the main purport of its growing process roughly coincides with non-added case as well as with controls. Also, the wandering velocity as well as time of continuance of the pseudoeosinocytes, though it was remarkably inhibited when the extract proved very dense, almost receive no other influence, and no significant differences with the controls could be discovered; i.e., the author could perceive that the increase in tissue growth rate by adding the bone-marrow extract was no result of activation of cell wandering, but it owes to the stimulation of growth in parenchymal cells themselves. Moreover, taking observation of the effect of bone marrow extract on the increase of hemoglobin as well as red blood cell number, under the culture in fluid medium, it was clarified that a certain of extract in a proper density brought about a marked increase in the amount, proving the existence of direct function by the extract. All through 3 reports the author have vindicated the fact that the improvement of medullary hematopoiesis by parenteral administration of so-called bone-marrow substances, may be caused not only by the vessel function, but also by the function of bone-marrow substance which has power to advance hematopoietic function.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasatomi
en-aut-sei=Fujii
en-aut-mei=Masatomi
kn-aut-name=藤井昌富
kn-aut-sei=藤井
kn-aut-mei=昌富
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部平木内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=67
cd-vols=
no-issue=1
article-no=
start-page=13
end-page=27
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1955
dt-pub=19550131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effect of the Bone-Marrow Autolysate on Medullary Hematopoiesis Part II: Influence of bone-marrow autolysate under splenectomy, liver parenchymal disturbance or reticuloendotherial blockade
kn-title=骨髓自家融解液の骨髓造血に及ぼす影響 第2編 剔脾，肝障碍，網内糸填塞の影響
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In the previous report, the author stated that there should happen a remarkably stimulated medullary hematopoiesis if the intra-abdominal injection of bone-marrow extract were successively rendered for a normal rabbit; this time, I conducted the following experiments in order to clarify whether these phenomena would activate indirectly through liver, spleen, or reticuloendotherial syetem, which are said to keep close relation with hematopoiesis, or, as Miyakawa maintained in this so-called "autohormone tbeory", functionate directly. First, having successively injected "bone-marrow extract" at 48 hours as well as 7 days after the splenectomy, the author examined its peripheral blood picture: this time, as was seen in the case of normal rabbit, biphasic blood cell increase was observed to take place, and an increase of reticulocytes number as well as a left shift of leucocytes were observed conspicuously, under the secondary blood cell increase. Consequently, it was verified that the same extract could stimulated the medullary hematopoiesis even under the influence of splenectomy. Next, by injecting likewise at 24 hours after the liver parenchymal disturbance, biphasic blood cell increase, an increase of reticulocytes number, and a left shift of leucocytes were noticed; moreover, even in case when the functions both of liver and spleen were removed at the same time, almost the same result as in the normal rabbit was obtained. In case the reticuloendotherial system was blocked with India-ink, even successive injection could not cause either increase of blood cell as well as left shift of leucocyte or improvement of intramedullary blood stream; that is to say, no medullary hematopoiesis was brought about. From the above results, the author concludes that the improvement of medullary hematopoiesis by successive intraabdominal injection of bone-marrow extract has no concern with either splenectomy or liver parenchymal disturbance, that the soundness of bone-marrow reticuloendotherial system should be indispensable requisite, and that this phenomenon might occur owing to the direct stimulation to bone-marrow parenchymal function.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasatomi
en-aut-sei=Fujii
en-aut-mei=Masatomi
kn-aut-name=藤井昌富
kn-aut-sei=藤井
kn-aut-mei=昌富
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部平木内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=67
cd-vols=
no-issue=1
article-no=
start-page=1
end-page=11
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1955
dt-pub=19550131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effect of the Bone-Marrow Autolysate on Medullary Hematopoiesis Part I: Intra-abdominal injection and test of artificial circulation through the femur
kn-title=骨髓自家融解液の骨髓造血に及ぼす影響 第1編 腹腔内注射並に骨髄灌流実験
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The author, as a link in the serial study on improvement of medullary hematopoiesis by so-called bone-marrow substance, tried to investigate both effects and functions of parenteral administration of rabbit's red bone-marrow autolysate (called simply as "bone-marrow extract" hereafter); so that, having injected its certain amount into normal rabbit's abdominal cavity, the author inspected its hourly effect on peripheral blood picture as well as on blood picture of V. nuturitica femoralis, and also took observations of certain changes that occurred to intramedullary circulation. As a result, the author discovered that: 1) the biphasic blood cell increase was induced in both cases of single and successive injection alike; 2) in its secondary blood cell increase, the increase was more remarkable in case of successive, than in case of single, injection; 3) above all, an increase of reticulocytes, a comparative increase of pseudoeosinocytes, and a left shift of leucocytes, were remarkably induced. Moreover, in case of the primary blood cell increase, an expansion of medullary nutric vessels, a marked blood cell increase in nutric veinal blood, and a comparative increase of pseudoeosinocytes --- i. e. a liberation of accumulated blood cells within bone-marrow --- were brought about; and further, the blood stream within bone-marrow under the two phases of blood cell increase was noticed to be remarkably stimulated, as compared with the case in normal rabbit. From the above results, it may roughly be said that, in case the bone-marrow extract should be intraabdominally injected, a biphasic blood cell increase occures in both cases of single and successive injection, the latter being more powerful in stimulating medullary hematopoiesis; and that the primary blood cell increase is caused by the mobilization as well as the liberation of accumulated blood cells which is due to the stimulation to blood stream within bone-marrow, while the secondary blood cell increase owes much to the hematopoietic function of bone-marrow which is originated in the continuance of stimulation to blood stream within bone-marrow.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasatomi
en-aut-sei=Fujii
en-aut-mei=Masatomi
kn-aut-name=藤井昌富
kn-aut-sei=藤井
kn-aut-mei=昌富
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部平木内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=8
article-no=
start-page=2121
end-page=2125
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1957
dt-pub=19570830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Microbiological Degradation of Bile Acids XV. Identification of a soil Bacterium isolated from a slaughter-yard
kn-title=胆汁酸の微生物学的分解 (XV) 胆汁酸を分解する一土壤菌について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A Gram-negative bacterium which was isolated from the soil of a slaughter-yard and was able to degrade cholic acid has been identified to be quite similar to Erwinia rhapontici.
en-copyright=
kn-copyright=

en-aut-name=FujiiTakao
en-aut-sei=Fujii
en-aut-mei=Takao
kn-aut-name=藤井孝郎
kn-aut-sei=藤井
kn-aut-mei=孝郎
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部生化学教室
END

start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=7
article-no=
start-page=1699
end-page=1710
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1957
dt-pub=19570731
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the Protein Metabolism of the Explanted Bone Marrow Culture in Rabbits Part Three Influences of Sera from various Patients on the Protein Metabolism in the Rabbit Bone Marrow
kn-title=家兎骨髓体外組織培養に於ける蛋白代謝の研究 第3編 各種疾患患者血清の家兎骨髄蛋白代謝に及ぼす影響
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=By loading the tissue culture (Carrel flask method) of the bone marrow of normal rabbits with sera of Patients suffering from various diseases, various factors involved in multiplication of the bone marrow at the same time the influences of these of these sera on the protein metabolism in the rabbit bone marrow have been investigated and the following are the results: (1) Sera of hypolastic anemia, Banti's disease, and of leukemia act directly on the bone marrow, and the presence of the substances inhibiting the marrow functions has been recognized, inhibiting the production of γ-globulin and fibrinogen by the marrow. (2) No substance acting directly on the bone marrow has been recognized in the sera of such blood disorders as essential hypochromic anemia, hookworm disease, Werlhof's disease, as well as in liver and kidney diseases or tuberculosis, and the loading of such sera to the marrow culture exerts no influence on the protein metabolism. (3) In the serum of cancer patient, the presence of substance slightly inhibiting the marrow functions has been recognized.
en-copyright=
kn-copyright=

en-aut-name=FujiiYukio
en-aut-sei=Fujii
en-aut-mei=Yukio
kn-aut-name=藤井幸雄
kn-aut-sei=藤井
kn-aut-mei=幸雄
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部平木内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=7
article-no=
start-page=1685
end-page=1698
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1957
dt-pub=19570731
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the Protein Metabolism of the Explanted Bone Marrow Culture in Rabbits Part Two The Protein Metabolism of the Bone Marrow in Experimental Anemic Rabbits
kn-title=家兎骨髓体外組織培養に於ける蛋白代謝の研究 第2編 実験的貧血家兎骨髄の蛋白代謝
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The protein metabolism of the bone marrow in experimental anemic rabbits had been studied with explanted bone marrow culture (Carrel flask method) and the following results were obtained: (1) The consumption of albumin and the production of globulin and fibrinogen, have been found to have rather decreased in the bone marrow of the rabbits given benzol for a short period of time. Next, in the case of the rabbits given benzol for a longer period of time. hypolasia of the bone marrow has been quite marked, namely, the consumption of albumin is low and production of globulin or of fibrinogen can hardly be noticed. (2) In the rabbits given saponin, the findings have been almost identical with those of the normal. (3) In the rabbits administered with phenylhydrazin or collargol, the marrow functions are low, the consumption of albumin slack, and the production of globulin and fibrinogen has been markedly low. (4) In the rabbits irradiated by x-rays, the marrow function have been completely deteriorated; namely, neither the consumption of albumin nor the production of globulin and fibrinogen can at all been seen.
en-copyright=
kn-copyright=

en-aut-name=FujiiYukio
en-aut-sei=Fujii
en-aut-mei=Yukio
kn-aut-name=藤井幸雄
kn-aut-sei=藤井
kn-aut-mei=幸雄
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部平木内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=7
article-no=
start-page=1669
end-page=1684
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1957
dt-pub=19570731
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the Protein Metabolism of the Explanted Bone Marrow Culture in Rabbits Part One Protein Metabolism of the Rabbit Bone Marrow, and Effects of Various Drugs on it
kn-title=家兎骨髓体外組織培養に於ける蛋白代謝の研究 第1編 正常家兎骨髄蛋白代謝並びに該代謝に及ぼす各種薬物の影響
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=By carrying out a series of observations on the protein metabolism by bone marrow culture (Carrel flask method) and on the effect of various drugs acting directly on the bone marrow, the following results have been obtained: (1) Albumin is utilized for multiplication of the bone marrow tissue while globulin is produced by the bone marrow. Consequently, the increase of globulin has a correlation with marrow functions in direct proportion. (2) In globulin fractions, γ-globulin seems to play the most important r?le. (3) Both α- and β-globulins seem to play no important r?le. (4) Fibrinogen is produced by the bone marrow, and it has a close relationship with marrow functions. (5) Folic acid, vitamin B12, and bone marrow extract directly stimulate marrow functions, and they promote the production of globulin, especially of γ-globulin and fibrinogen on one hand, and the consumption of albumin on the other hand. (6) Nitromin (Nitrogen mustard-N-oxyde) lowers functions of the bone marrow and inhibits the production of globulin, paricularly γ-globulin and fibrinogen, and the consumption of albumin.
en-copyright=
kn-copyright=

en-aut-name=FujiiYukio
en-aut-sei=Fujii
en-aut-mei=Yukio
kn-aut-name=藤井幸雄
kn-aut-sei=藤井
kn-aut-mei=幸雄
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部平木内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=9
cd-vols=
no-issue=3
article-no=
start-page=171
end-page=178
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1978
dt-pub=19780315
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=T. Fujimoto, Models of Optimal Economic Policy
kn-title=藤本利躬著 「最適経済政策のモデル」
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiT.
en-aut-sei=Fujii
en-aut-mei=T.
kn-aut-name=藤井隆
kn-aut-sei=藤井
kn-aut-mei=隆
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=名古屋大学
END

start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=201
end-page=212
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Structural diversity in flagella of enteropathogenic E. coli
kn-title=病原性大腸菌（EPEC）の鞭毛構造の多様性
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The ultrastructure of flagella of enteropathogenic E. coli was analysed by electron microscopy. The flagella of E. coli 0126, 026, 0114 and 0128, each of which have different H antigen types, were tentatively classified into four types according to their ultrastructural similarity. The appearence of most flagella structures were homologous in each H type and identical with a previous report (Lawn, AM, 1977). However, the structure of H31, H25 and H48 were different from the previous ones and H11 (026K60) and H25 (026K60) showed two different types of flagella structure in a single H type. Immuno-electron microscopy using gold-labeled anti-rabbit IgG goat antibody disclosed that there were anti H type sera reactive flagella and non reactive flagella in both Hll and H25, although the molecular weight of each flagellin showed one homologous band by SDS-PAGE. The result suggests that there is a certain diversity in the manner of self assembly of flagellin to form flagella structures.
en-copyright=
kn-copyright=

en-aut-name=FujiiTakashi
en-aut-sei=Fujii
en-aut-mei=Takashi
kn-aut-name=藤井高志
kn-aut-sei=藤井
kn-aut-mei=高志
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部細菌学教室
en-keyword=病原性大腸菌
kn-keyword=病原性大腸菌
en-keyword=鞭毛超微構造
kn-keyword=鞭毛超微構造
en-keyword=H型抗原
kn-keyword=H型抗原
en-keyword=フラジェリン
kn-keyword=フラジェリン
END

start-ver=1.4
cd-journal=joma
no-vol=122
cd-vols=
no-issue=3
article-no=
start-page=249
end-page=251
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2010
dt-pub=20101201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Evidence-based guidelines for the management of biliary tract cancer
kn-title=胆道癌診療ガイドライン
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiMasakuni
en-aut-sei=Fujii
en-aut-mei=Masakuni
kn-aut-name=藤井雅邦
kn-aut-sei=藤井
kn-aut-mei=雅邦
aut-affil-num=1
ORCID=

en-aut-name=KawamotoHirofumi
en-aut-sei=Kawamoto
en-aut-mei=Hirofumi
kn-aut-name=河本博文
kn-aut-sei=河本
kn-aut-mei=博文
aut-affil-num=2
ORCID=

en-aut-name=YamamotoKazuhide
en-aut-sei=Yamamoto
en-aut-mei=Kazuhide
kn-aut-name=山本和秀
kn-aut-sei=山本
kn-aut-mei=和秀
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・肝臓内科学

affil-num=2
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・肝臓内科学

affil-num=3
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・肝臓内科学
END

start-ver=1.4
cd-journal=joma
no-vol=122
cd-vols=
no-issue=3
article-no=
start-page=225
end-page=229
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2010
dt-pub=20101201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Usefulness of the waterless method for surgical hand washing：A comparison with the conventional scrub method
kn-title=手術時手洗いにおける従来法とツーステージ・サージカルスクラブ法，ウォーターレス法の比較について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=To evaluate the usefulness of the waterless hand washing method for surgical anti-sepsis, we conducted a microbial sampling study, comparing it to a conventional surgical scrub method. A total of 18 operating-room nurses were undertaking the following three-hand washing protocols : scrubbing with blushes using 4w/v% chlorhexidine gluconate (CHG) and also rubbing with CHG, followed by application of a 0.2w/v% CHG with ethanol (HS) preparation. (conventional method); rubbing with CHG and application of HS (two-stage surgical scrub method; TSS); rubbing with anti-septic soap and application of HS (waterless method; WL). Microbial sampling was conducted after hand washing using the glove juice method. No statistically significant differences in bacterial numbers were found among these three methods. The number of bacterially positive subjects was significantly higher in the conventional method than the TSS method. These results indicate that there are adverse effects of blush-scrubbing, as the detected bacteria were related to normal skin flora. As such, the WL method for hand anti-sepsis appears to be equivalent to the conventional surgical scrubbing method in terms of microbial detection. The WL method should therefore be introduced as a standard hand anti-sepsis method at the time of surgery because it is cost-effective as well as time-efficient.
en-copyright=
kn-copyright=

en-aut-name=KobayashiYuka
en-aut-sei=Kobayashi
en-aut-mei=Yuka
kn-aut-name=小林由佳
kn-aut-sei=小林
kn-aut-mei=由佳
aut-affil-num=1
ORCID=

en-aut-name=YamadaMisa
en-aut-sei=Yamada
en-aut-mei=Misa
kn-aut-name=山田美佐
kn-aut-sei=山田
kn-aut-mei=美佐
aut-affil-num=2
ORCID=

en-aut-name=FujiiHiromi
en-aut-sei=Fujii
en-aut-mei=Hiromi
kn-aut-name=藤井裕美
kn-aut-sei=藤井
kn-aut-mei=裕美
aut-affil-num=3
ORCID=

en-aut-name=KoYukiko
en-aut-sei=Ko
en-aut-mei=Yukiko
kn-aut-name=甲由紀子
kn-aut-sei=甲
kn-aut-mei=由紀子
aut-affil-num=4
ORCID=

en-aut-name=UotaniIzumi
en-aut-sei=Uotani
en-aut-mei=Izumi
kn-aut-name=魚谷いづみ
kn-aut-sei=魚谷
kn-aut-mei=いづみ
aut-affil-num=5
ORCID=

en-aut-name=TamotoMariko
en-aut-sei=Tamoto
en-aut-mei=Mariko
kn-aut-name=田本真理子
kn-aut-sei=田本
kn-aut-mei=真理子
aut-affil-num=6
ORCID=

en-aut-name=NadaMasako
en-aut-sei=Nada
en-aut-mei=Masako
kn-aut-name=名田正子
kn-aut-sei=名田
kn-aut-mei=正子
aut-affil-num=7
ORCID=

en-aut-name=MuraiHiroyuki
en-aut-sei=Murai
en-aut-mei=Hiroyuki
kn-aut-name=村井裕之
kn-aut-sei=村井
kn-aut-mei=裕之
aut-affil-num=8
ORCID=

en-aut-name=KadoEi
en-aut-sei=Kado
en-aut-mei=Ei
kn-aut-name=角英
kn-aut-sei=角
kn-aut-mei=英
aut-affil-num=9
ORCID=

en-aut-name=IwagakiHiromi
en-aut-sei=Iwagaki
en-aut-mei=Hiromi
kn-aut-name=岩垣博巳
kn-aut-sei=岩垣
kn-aut-mei=博巳
aut-affil-num=10
ORCID=

en-aut-name=TomodaJun
en-aut-sei=Tomoda
en-aut-mei=Jun
kn-aut-name=友田純
kn-aut-sei=友田
kn-aut-mei=純
aut-affil-num=11
ORCID=

en-aut-name=SaitoShinya
en-aut-sei=Saito
en-aut-mei=Shinya
kn-aut-name=斎藤信也
kn-aut-sei=斎藤
kn-aut-mei=信也
aut-affil-num=12
ORCID=

affil-num=1
en-affil=
kn-affil=国立病院機構福山医療センター　看護部

affil-num=2
en-affil=
kn-affil=国立病院機構福山医療センター　看護部

affil-num=3
en-affil=
kn-affil=国立病院機構福山医療センター　看護部

affil-num=4
en-affil=
kn-affil=国立病院機構福山医療センター　看護部

affil-num=5
en-affil=
kn-affil=国立病院機構福山医療センター　看護部

affil-num=6
en-affil=
kn-affil=国立病院機構福山医療センター　看護部

affil-num=7
en-affil=
kn-affil=国立病院機構福山医療センター　看護部

affil-num=8
en-affil=
kn-affil=国立病院機構福山医療センター　臨床検査部

affil-num=9
en-affil=
kn-affil=国立病院機構福山医療センター　薬剤部

affil-num=10
en-affil=
kn-affil=国立病院機構福山医療センター　外科

affil-num=11
en-affil=
kn-affil=国立病院機構福山医療センター　内科

affil-num=12
en-affil=
kn-affil=岡山大学大学院保健学研究科　感染管理学
en-keyword=手洗い (hand washing)
kn-keyword=手洗い (hand washing)
en-keyword=手指消毒 (hand antisepsis)
kn-keyword=手指消毒 (hand antisepsis)
en-keyword=ツーステージ・サージカルスクラブ法 (surgical scrub method)
kn-keyword=ツーステージ・サージカルスクラブ法 (surgical scrub method)
en-keyword=ウォーターレス法 (waterless method)
kn-keyword=ウォーターレス法 (waterless method)
en-keyword=手術 (surgery)
kn-keyword=手術 (surgery)
END

start-ver=1.4
cd-journal=joma
no-vol=36
cd-vols=
no-issue=1
article-no=
start-page=41
end-page=62
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2004
dt-pub=20040610
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=“Final Fantasy” in The Rise : Business Case of Square Co. Ltd., A Home Video Game Software Factory
kn-title=『ファイナル・ファンタジー』の誕生―株式会社スクウェアによる家庭用ゲーム・ソフト開発の事例―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=37
cd-vols=
no-issue=3
article-no=
start-page=13
end-page=31
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=20051210
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A view on incentive planning for R&D workers through a case study of the blue LED patent lawsuits in Japan
kn-title=研究開発におけるインセンティブ−青色LED 裁判のケーススタディ−
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The purpose of this paper is to bring an institutional perspective onto the recent debates about incentive planning for R&D workers in Japan. This purpose is fulfilled through a case study of the recent civil trials in which an ex?employee as a plaintiff claimed any compensation for the corporate in?house inventions about blue light emitting diodes (LED). As long as technical achievements are to belong to an individual worker, the incentive planning which his or her employer may design will have to face two difficult tasks. Firstly, marginal analyses commonly applied in micro economics have certain utilities under the strict assumption of decreasing returns to productive inputs, but not applicable, in principle, to R&D activities. It is because such features as experiential learning and teamwork by technical professionals may increase returns to marginal inputs of technical labor. Secondly, negotiation transactions on the arms lengths basis are alternatively applied instead of the first, but incur many transaction costs between opportunistic players. Recent Japan seems oriented toward the second planning arrangement, but this paper suggests that the economic assessments of corporate in?house inventions should be complemented by peer reviews on the
expectation that professional communities of technical experts share certain paradigms to tell us which inventions are more nascent and valuable and which are not. So far, it is said that these peer reviews have been submitted to courts after plaintiffs file complaints for compensations, but preliminary reviews at the time of patent applications may effectively decrease the probability of unexpected lawsuits and reprieve undue legal costs.
en-copyright=
kn-copyright=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=37
cd-vols=
no-issue=1
article-no=
start-page=63
end-page=88
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=20050610
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=The Birth of “Final Fantasy”: Square Corporation
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=37
cd-vols=
no-issue=1
article-no=
start-page=19
end-page=34
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=20050610
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Entrepreneurial Choices in Strategic Options in Japan’s RPG Development
kn-title=ゲームソフト開発における戦略オプションの選択
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The purpose of this paper is to examine one of the functions which entrepreneurs may play in the course of industrial development through a case study of Japan’s RPG development race. As Japan’s toy manufacturers often said, their market was characteristic of its small size and considerable demand volatility in comparison to other consumer products. Entrepreneurs must have seen any commitment to a cutting edge product, video games, as only a gamble and therefore behaved in a trial?and?error way. Furthermore, judging from the fact that no one could imagine the video game would come to turn over ?1500 billion in 20 years, the firm level trial?and?errors and their subsequent variety of strategies on the industry level must have been the key to understand the unexpected market growth and technical evolution. However, recent management thoughts told us that the strategic variety in an industry could be possibly indulged by various pressures towards homogeneity. Such counter powers are referred to as organizational isomorphism, strategic bandwagon effects and so on. To examine those pressures which drive entrepreneurs back and forth towards strategic variety, this paper looks at the structural characteristics which underlie the way entrepreneurs see things in an uncertain environment. The case analysis takes the view that the video game industry was so uncertain that nothing could affect so deterministically entrepreneurs’ behaviours other than their perceptions. As a conclusion here, this paper points out some tradeoffs underlying the two different strategies which the twin peaks of Japanese RPG producers, Square and Enix, employed to meet with the uncertainty of the infant RPG market. It also argues that these tradeoffs based on two different perceptions might have kept their startups from the isomorphic indulgence. As a more prospective argument, questioned is the quality of strategic variety which is often deemed as an unquestionable remedy to industrial stagnation.
en-copyright=
kn-copyright=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=122
cd-vols=
no-issue=2
article-no=
start-page=159
end-page=162
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2010
dt-pub=20100802
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Japanese guidelines for coxarthrosis
kn-title=変形性股関節症
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiwaraKazuo
en-aut-sei=Fujiwara
en-aut-mei=Kazuo
kn-aut-name=藤原一夫
kn-aut-sei=藤原
kn-aut-mei=一夫
aut-affil-num=1
ORCID=

en-aut-name=EndoHirosuke
en-aut-sei=Endo
en-aut-mei=Hirosuke
kn-aut-name=遠藤裕介
kn-aut-sei=遠藤
kn-aut-mei=裕介
aut-affil-num=2
ORCID=

en-aut-name=MiyakeYoshiaki
en-aut-sei=Miyake
en-aut-mei=Yoshiaki
kn-aut-name=三宅由晃
kn-aut-sei=三宅
kn-aut-mei=由晃
aut-affil-num=3
ORCID=

en-aut-name=OzakiToshifumi
en-aut-sei=Ozaki
en-aut-mei=Toshifumi
kn-aut-name=尾�ｱ敏文
kn-aut-sei=尾�ｱ
kn-aut-mei=敏文
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学病院　整形外科

affil-num=2
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　運動器医療材料開発

affil-num=3
en-affil=
kn-affil=岡山大学病院　整形外科

affil-num=4
en-affil=
kn-affil=岡山大学病院　整形外科
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=4
article-no=
start-page=169
end-page=180
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2004
dt-pub=200408
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=A spectrum of clinical manifestations caused by host immune responses against Epstein-Barr virus infections.
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=<p>Epstein-Barr virus (EBV), or human herpesvirus 4 (HHV-4), infects the vast majority of adults worldwide, and establishes both nonproductive (latent) and productive (lytic) infections. Host immune responses directed against both the lytic and latent cycle-associated EBV antigens induce a diversity of clinical symptoms in patients with chronic active EBV infections who usually contain an oligoclonal pool of EBV-infected lymphocyte subsets in their blood. Episomal EBV genes in the latent infection utilize an array of evasion strategies from host immune responses: the minimized expression of EBV antigens targeted by host cytotoxic T lymphocytes (CTLs), the down-regulation of cell adhesion molecule expression, and the release of virokines to inhibit the host CTLs. The oncogenic role of latent EBV infection is not yet fully understood, but latent membrane proteins (LMPs) expressed during the latency cycle have essential biological properties leading to cellular gene expression and immortalization, and EBV-encoded gene products such as viral interleukin-10 (vIL-10) and bcl-2 homologue function to survive the EBV-infected cells. The subsequent oncogenic DNA damage may lead to the development of neoplasms. EBV-associated NK/T cell lymphoproliferative disorders are prevalent in Asia, but quite rare in Western countries. The genetic immunological background, therefore, is closely linked to the development of EBV-associated neoplasms.</p>
en-copyright=
kn-copyright=

en-aut-name=IwatsukiKeiji
en-aut-sei=Iwatsuki
en-aut-mei=Keiji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=YamamotoTakenobu
en-aut-sei=Yamamoto
en-aut-mei=Takenobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=TsujiKazuhide
en-aut-sei=Tsuji
en-aut-mei=Kazuhide
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=SuzukiDaisuke
en-aut-sei=Suzuki
en-aut-mei=Daisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=FujiiKazuyasu
en-aut-sei=Fujii
en-aut-mei=Kazuyasu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=MatsuuraHironori
en-aut-sei=Matsuura
en-aut-mei=Hironori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=OonoTakashi
en-aut-sei=Oono
en-aut-mei=Takashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=Okayama University

affil-num=2
en-affil=
kn-affil=Okayama University

affil-num=3
en-affil=
kn-affil=Okayama University

affil-num=4
en-affil=
kn-affil=Okayama University

affil-num=5
en-affil=
kn-affil=Okayama University

affil-num=6
en-affil=
kn-affil=Okayama University

affil-num=7
en-affil=
kn-affil=Okayama University
en-keyword=latent infection
kn-keyword=latent infection
en-keyword=hydroa vacciniforme
kn-keyword=hydroa vacciniforme
en-keyword=mosquito allergy
kn-keyword=mosquito allergy
en-keyword=chronic active EB virus infection
kn-keyword=chronic active EB virus infection
en-keyword=hemophagocytic syndrome
kn-keyword=hemophagocytic syndrome
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=
article-no=
start-page=61
end-page=65
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1983
dt-pub=19830325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case report of a patient with chronic pancreatitis successfully treated by endoscopic elimination of protein plugs
kn-title=内視鏡的protein plug除去術により寛解を得た慢性膵炎の一例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Presented here is a case report of a 56 years old male patient with chronic pancreatitis in which a dramatic improvement in symptoms and objective findings were noted after endoscopic elimination of protein plugs. In September, 1979, he had an acute onset of pancreatitis followed by pseudocyst formation and the following combined operations were performed: resection of the pseudocyst, resection of the body and tail of the pancreas along with the spleen, partial resection of the stomach and the transverse colon, and gastroenterostomy according to Billroth I method. He had been followed up at out-patient clinic for chronic pancreatitis and diabetes until January 14,1979 when he was hospitalized for anorexia, loss of weight, pretibial edema, and upper-abdominal pain. The patient's condition was characterized by emaciation (height 152 cm, weight 37 kg), anemia (Hb 7.9g/dl), hypoproteinemia (serum protein 4.2 g/dl) , and hypolipidemia (total cholesterol 73 mg/dl). Abdominal ultrasound, abdominal CT and ERCP revealed stones in the pancreatic duct. Symptoms and objective findings were only partially improved by medical regimens. Subsequently we performed endoscopic cannulation of the pancreatic duct for elimination of pancreatic stones. Successful elimination of large numbers of protein plugs resulted in dramatic improvement of symptoms and objective findings. This procedure proved to add a new important tool in the treatment of chronic pancreatitis.
en-copyright=
kn-copyright=

en-aut-name=TakedaMasahiko
en-aut-sei=Takeda
en-aut-mei=Masahiko
kn-aut-name=武田正彦
kn-aut-sei=武田
kn-aut-mei=正彦
aut-affil-num=1
ORCID=

en-aut-name=TanakaJuntaro
en-aut-sei=Tanaka
en-aut-mei=Juntaro
kn-aut-name=田中淳太郎
kn-aut-sei=田中
kn-aut-mei=淳太郎
aut-affil-num=2
ORCID=

en-aut-name=TakasugiKiyoshi
en-aut-sei=Takasugi
en-aut-mei=Kiyoshi
kn-aut-name=高杉潔
kn-aut-sei=高杉
kn-aut-mei=潔
aut-affil-num=3
ORCID=

en-aut-name=HaradaHideo
en-aut-sei=Harada
en-aut-mei=Hideo
kn-aut-name=原田英雄
kn-aut-sei=原田
kn-aut-mei=英雄
aut-affil-num=4
ORCID=

en-aut-name=ManjiTadatomi
en-aut-sei=Manji
en-aut-mei=Tadatomi
kn-aut-name=万治忠福
kn-aut-sei=万治
kn-aut-mei=忠福
aut-affil-num=5
ORCID=

en-aut-name=MorinagaHiroshi
en-aut-sei=Morinaga
en-aut-mei=Hiroshi
kn-aut-name=森永寛
kn-aut-sei=森永
kn-aut-mei=寛
aut-affil-num=6
ORCID=

en-aut-name=TsurumiTetsuya
en-aut-sei=Tsurumi
en-aut-mei=Tetsuya
kn-aut-name=鶴見哲也
kn-aut-sei=鶴見
kn-aut-mei=哲也
aut-affil-num=7
ORCID=

en-aut-name=FujiiYasuhisa
en-aut-sei=Fujii
en-aut-mei=Yasuhisa
kn-aut-name=藤井靖久
kn-aut-sei=藤井
kn-aut-mei=靖久
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学温泉研究所温泉内科学部門

affil-num=2
en-affil=
kn-affil=岡山大学温泉研究所温泉内科学部門

affil-num=3
en-affil=
kn-affil=岡山大学温泉研究所温泉内科学部門

affil-num=4
en-affil=
kn-affil=岡山大学温泉研究所温泉内科学部門

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=7
en-affil=
kn-affil=愛媛県立中央病院内科

affil-num=8
en-affil=
kn-affil=愛媛県立中央病院内科
END

start-ver=1.4
cd-journal=joma
no-vol=8
cd-vols=
no-issue=
article-no=
start-page=1
end-page=20
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2010
dt-pub=20100326
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An Essay on Comparative Case Analyses in Management Studies (Part 2)
kn-title=経営学における比較事例研究法に関する一考察 (2)
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiDaiji
en-aut-sei=Fujii
en-aut-mei=Daiji
kn-aut-name=藤井大児
kn-aut-sei=藤井
kn-aut-mei=大児
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学社会文化科学研究科組織経営専攻
END

start-ver=1.4
cd-journal=joma
no-vol=21
cd-vols=
no-issue=
article-no=
start-page=31
end-page=33
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2004
dt-pub=200409
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effect of Beni-Koji on Blood Pressure and Learning Behavior in Spontaneously Hypertensive Rats
kn-title=高血圧自然発症ラットの血圧および学習行動に及ぼす紅麹の影響
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1)紅麹投与群は米粉を投与した対照群と比べ､体重増加に対しては有意な差は認められなかった｡ 2)紅麹投与群は対照群と比べ2週目より有意な血圧下降作用が認められた｡ 3)紅麹投与群は､対照群に比べ総エラー数および参照記憶エラー数の減少､すなわち学習獲得能が高いことが判明した｡ 4)以上の成績より､紅麹の投与により生じた血圧下降が二次的に学習獲得能を上昇させたのではないかと考えられる｡
en-copyright=
kn-copyright=

en-aut-name=ShinomiyaKazuaki
en-aut-sei=Shinomiya
en-aut-mei=Kazuaki
kn-aut-name=四宮一昭
kn-aut-sei=四宮
kn-aut-mei=一昭
aut-affil-num=1
ORCID=

en-aut-name=AdachiYutaka
en-aut-sei=Adachi
en-aut-mei=Yutaka
kn-aut-name=安達豊
kn-aut-sei=安達
kn-aut-mei=豊
aut-affil-num=2
ORCID=

en-aut-name=ShigemotoYuki
en-aut-sei=Shigemoto
en-aut-mei=Yuki
kn-aut-name=重本有紀
kn-aut-sei=重本
kn-aut-mei=有紀
aut-affil-num=3
ORCID=

en-aut-name=KounoIsato
en-aut-sei=Kouno
en-aut-mei=Isato
kn-aut-name=河野勇人
kn-aut-sei=河野
kn-aut-mei=勇人
aut-affil-num=4
ORCID=

en-aut-name=FujiiYoko
en-aut-sei=Fujii
en-aut-mei=Yoko
kn-aut-name=藤井陽子
kn-aut-sei=藤井
kn-aut-mei=陽子
aut-affil-num=5
ORCID=

en-aut-name=KameiChiaki
en-aut-sei=Kamei
en-aut-mei=Chiaki
kn-aut-name=亀井千晃
kn-aut-sei=亀井
kn-aut-mei=千晃
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学薬学部薬物作用解析学

affil-num=2
en-affil=
kn-affil=岡山大学薬学部薬物作用解析学

affil-num=3
en-affil=
kn-affil=岡山大学薬学部薬物作用解析学

affil-num=4
en-affil=
kn-affil=岡山県工業技術センター

affil-num=5
en-affil=
kn-affil=岡山大学薬学部薬物作用解析学

affil-num=6
en-affil=
kn-affil=岡山大学薬学部薬物作用解析学
END

start-ver=1.4
cd-journal=joma
no-vol=99
cd-vols=
no-issue=1
article-no=
start-page=43
end-page=47
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2010
dt-pub=20100201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effect of Controlled-release Fertilizer and Root-proof Capillary Wick Addition to Root-zone on Tomato Growth and Yield
kn-title=トマトの防根給水ひも栽培における肥効調節型肥料と根域拡張に伴う「紐」の適用
en-subtitle=
kn-subtitle=
en-abstract=中玉トマト18段摘心の長期促成栽培における肥効調節型肥料の適用と生育途中の根域拡張に伴う「紐」適用が生育と果実収量に及ぼす効果を調べた．栽培容器は可動仕切り板で2つに仕切り区画当たり容量は2.8?とし，第8段花房開花時に仕切り板をはずして5.6?（1st Box＋2nd Box）とした．試験区は2区で2nd Boxに紐を配置しない1本区と2nd Boxにもう１本を配した2本区である．2本区の草丈は1月以降，1本区に比べ高く推移し第18段花房の開花日が約10日早まり，成長の指標とした摘心時の茎頂部新鮮重も1本区の2倍となった．1株の果実収量は1本区で8kg，2本区で9kgとなり果実の糖度，酸度には両区間に差はなかった．栽培終了時の根の乾物重と茎切断面から採取した木部いっ泌液は両区間に差はなかったが，両区とも栽培終期の4月には生育が衰え葉色は黄緑色で果実の着色も不均一であった．木部いっ泌の成分分析ではNO(3)-N濃度が1本区で10me/?，2本区で6me/?であり，これらの濃度は一般に養液栽培に使用される園試標準濃度よりも低かった．以上の結果から，第8段花房開花時に仕切りを開放し新区画への土壌と肥料ならびに紐の新たな適用は，生育安定と収量確保に効果的に作用することが明らかとなった．しかし，紐の有無にかかわらず生育後期の生育が不良となったことから，今後は施肥設計の面から，とくにNO(3)-NとSO(4)-Sの両面から検討する必要があると考察した．
kn-abstract=This study was conducted to investigate the effects of controlled-release fertilizers and wick addition to the root-zone on plant growth and yield of medium-fruit sized tomato up to the 18(th) truss in long-term forcing culture. The set-up consisted of a box partitioned by a board into two halves, named box 1 and box 2. Box 1 contained 2.8 ? of growth medium (soil : bark : perlite : peat=2 : 2 : 1 : 1). Plant was grown in box 1 with a capillary wick, and at flowering of the 8(th) truss, the partition was removed and box 2 filled with 2.8 ? of the medium. There were two treatments, with or without capillary wick in box 2, namely, single wick (S) and double wicks (D). Plant height was greater in D than S in January, and the difference increased gradually thereafter. Flowering time of 18(th) truss in D was 10 days earlier and decapitated shoot weight was twice that of S. Fruit yield per plant was 8 kg in S and 9 kg in D with similar value of Brix and titratable acidity. There was no difference between S and D in dry root weight (7g/plant) or in xylem exudates (8ml/h), while in S in April plant growth was inferior, leaf color yellow greenish and fruit colour uneven towards the end of growth of plants. Xylem sap analysis showed that NO(3)-N was 10 me/? in S and 6 me/? in D. This concentration is weaker than that of Enshi standard nutrient solution generally used in hydroponics. These results suggest that application of controlled-release fertilizers and wick addition to box 2 with root-zone extended was effective for plant growth performance and fruit yield.
en-copyright=
kn-copyright=

en-aut-name=MasudaMasaharu
en-aut-sei=Masuda
en-aut-mei=Masaharu
kn-aut-name=桝田正治
kn-aut-sei=桝田
kn-aut-mei=正治
aut-affil-num=1
ORCID=

en-aut-name=FujiiYuki
en-aut-sei=Fujii
en-aut-mei=Yuki
kn-aut-name=藤井由貴
kn-aut-sei=藤井
kn-aut-mei=由貴
aut-affil-num=2
ORCID=

en-aut-name=KinoshitaTakafumi
en-aut-sei=Kinoshita
en-aut-mei=Takafumi
kn-aut-name=木下貴文
kn-aut-sei=木下
kn-aut-mei=貴文
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=(独)農業・食品産業技術総合研究機構近畿中国四国農業研究センター
en-keyword=capillary watering
kn-keyword=capillary watering
en-keyword=combination of fertilizer
kn-keyword=combination of fertilizer
en-keyword=medium-fruit sized tomato
kn-keyword=medium-fruit sized tomato
en-keyword=sectional box
kn-keyword=sectional box
en-keyword=substrate volume
kn-keyword=substrate volume
END

start-ver=1.4
cd-journal=joma
no-vol=68
cd-vols=
no-issue=1-4
article-no=
start-page=95
end-page=107
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1956
dt-pub=19560430
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the Specifity in Direct Functions of Leukocyte Autolysate. �V. Additional Tests towards the Tissue Cultures of the Bone-marrow and Lymphnodes, and Conclusionsto Entire Series
kn-title=白血球自家融解液の所謂直接作用の特異性に関する研究 第3編 骨髄並に淋巴節 体外組織培養への添加実験 附,全編を通じての考察並に結論
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In the previous chapters, I have described the so-called direct functions indicated by pseudoeosinocytes, eosinophil leukocytes, as well as lymphocytes, at the same time examining their mechanism. In this, I am going to discuss the case in which the above mentioned leukocytic extract has been added to the tissue culture of the bone-marrow and lymphnodes. 1) In case pseudoeosinocyte extract are added to any tissue culture of rabbit's bone-marrow, an improvement of tissue growth rate (i.e., an increase in pseudoeosinocytes) as well as an excitement in their wandering velocity are achieved in comparative particularity. 2) If I add lymphocytic extract to a rabbit's lymphnode culture, there happens in comparative unique mode, an improvement in the tissue growth rate (i.e., lymphocytic increase), and the lymphocyte rises in its wandering velocity. 3) If I add guinea-pig's eosinophil leukocytes extract on the culture of the same animal's　bone-marrow, it induce an increase of eosinophil leukocytes in the growth zone, together with a rise in the wandering velocity of the same. 4) I evidenced that the direct influence of leukocyte extract explained in 1st and 2nd chapter, acts on the bone-marrow and lymphnodes in a direct manner. Conclusions. Owing to those ezperimental results obtained throughout these chapters, I can conclude as folllows: i.e. The extracts stimulate the bone-marrow or lymphnode directly with comparative specifity, no matter how the liver and spleen might stand, and induce the
increase of each sort of leukocytes respectively and of their. wandering velocity so that they appear in the peripheral blood in short time, though it is better that the reticuloendothelial system is normal.
en-copyright=
kn-copyright=

en-aut-name=FujiiSeiji
en-aut-sei=Fujii
en-aut-mei=Seiji
kn-aut-name=藤井正二
kn-aut-sei=藤井
kn-aut-mei=正二
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部平木内科
END

start-ver=1.4
cd-journal=joma
no-vol=68
cd-vols=
no-issue=1-4
article-no=
start-page=73
end-page=93
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1956
dt-pub=19560430
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the Specifity in Direct Functions of Leukocyte Autolysate. �U. Experiments in splenectomy, liver parenchymal disturbance, or reticuloendothelial blockade, that have happened to each animal group
kn-title=白血球自家融解液の所謂直接作用の特異性に関する研究 第2編 別脾，肝細胞障碍及び網内系填塞の各動物群に就いての実験
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=I reported in the 1st chapter the fact, that tle specific increase of each leukocyte is evidenced in the peripheral blood, bone-marrow and in the lymphatic tissue of the normal rabbit or guinea-pig injected with the extract from pseudoeosinophil, eosinophil or lymphatic leukocytes. ln this chapter, I, employing such animals as have undergone either splenectomy, liver parenchymal disturbance, or reticuloendothelial blockade, examined to get certain detailed notions as to their functions, from which, results as follows were obtained. 1) When the extracts out of the pseudoeosinocytes or eosinophil leukocytes have been applied to splenectomized or disturbed liver parenchy animal, an increase of each leukocyte was induced respectively, same as was seen in 1st chapter. 2) When the pseudoeosinocyte extract or eosinophil leukocyte extract was applied to animals of reticaloendothelial blockade, different from the case in 1st chapter, a feeble sort of increase took place in case of pseudoeosinocyte extract, While with the latter, no brieftime increase has appeared, but only when 24 hours have lapsed. 3) If lymphocyte extract was injected in animals with splenectomy, liver parenchymal disturbance or reticuloendothelial blockade, though the was seen no blood lymphocyte increase, same remarkable proliferation as stated in 1st chapter was detected.
en-copyright=
kn-copyright=

en-aut-name=FujiiSeiji
en-aut-sei=Fujii
en-aut-mei=Seiji
kn-aut-name=藤井正二
kn-aut-sei=藤井
kn-aut-mei=正二
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部平木内科
END

start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=4-2
article-no=
start-page=1969
end-page=1988
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1959
dt-pub=19590405
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Electrophysiological Study on the Pallidofugal Fibers as the Conduction System of Epileptic Discharges
kn-title=癲癇痙攣伝導路としての遠淡蒼球線維に関する生理学的研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In this study, the auther has attempt to study electrophysiologically the aspect of pallidofugal fibers which are intermediated by the pallidum to the fibers arising from the motor area as the conduction system of epileptic discharge. Action potentials of motor cortex, basal ganglia, nuclei of the midbrain and spinal cord were recorded during major convulsive or subclinical seizures which are elicited by local administration of metrazol to the motor cortex or the thalamus of dogs. For subcortical recordings, a pair of bipor needle electrodes made of steel wire, mapproximately 200 μ in diameter on tungsten microelectrodes approximately 20 μ in diameter at the tip were used. Both steel and tungsten electrodes insulated by baking enamel except the tip. Spike discharges (duration of each spike is 20-60 msec. amplitude 50-100 μV recorded by abovementioned electrodes) are accounted for the epileptic discharges in this study. The results were as follows: 1) There are two different pathways transmitting the discharges from the motor area to the pallidum, one is direct connection between the motor cortex to the pallidum and the other has some relays the nuclei, thalamus and caudate nucleus, between them. These different pathways are connected separately to two different pallidofugal fiber group at the pallidum. 2) The pallidofugal fiber group, which is connected to the former pathways at the pallidum, are relayed at the contralateral substantia nigra and then terminated to anterior horn cells of the spinal cord. There is a fiber crossing to the other side at the midbrain between the pallidum and substantia nigra. 3) The pallidofugal fiber group connected to the latter at the pallidum does not show crossing to the other side on its course to the homolateral substantia nigra. But the downward fibers from the substantia nigra show a crossing to the other side at the pons and terminate in the contralateral anterior horn cells.
en-copyright=
kn-copyright=

en-aut-name=FujiiShinichiro
en-aut-sei=Fujii
en-aut-mei=Shinichiro
kn-aut-name=藤井愼一郎
kn-aut-sei=藤井
kn-aut-mei=愼一郎
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第1外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=9
cd-vols=
no-issue=
article-no=
start-page=1
end-page=190
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=200803
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=「岡山大学生のジェンダー意識に関する調査」報告書
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=ジェンダーの多様性・普遍性・可変性の分析および独自のジェンダー教育プログラムの立案を含む学際的研究グループ
kn-aut-sei=ジェンダーの多様性・普遍性・可変性の分析および独自のジェンダー教育プログラムの立案を含む学際的研究グループ
kn-aut-mei=
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=73
cd-vols=
no-issue=10-12
article-no=
start-page=733
end-page=747
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1961
dt-pub=19611230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Electromyographic Study on Tonic and Kinetic Motor Units
kn-title=筋電図によるkineticなるびにtonic motor unitの特性に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=It became recently known that there are two types of characteristic spikes in EMG at voluntary contruction of skeletal muscle; the one is of low voltage and long duration, and the other, of high voltage and short duration. In this study a detailed observation was done for analysis of these spikes. 1) They would not be changed in duration by alternation of the recording electrode position. 2) In the histograms of the voltage and duration of the spikes recorded separately from flexor digitorum profudus muscle and soleus muscle, it was revealed that the one from the first muscle was of 50-550 μV in voltage range with two peaks at 100-200 μV and 300-450　μV and of 0.5-5.5 ms in duration range with also two peaks at 1.0-1.5 ms and 2.0-3.0 ms. The one from the latter muscle was ranged in similar manner as in the first, but the peak was found solely at 100-150 μV in voltage and 2.5-3.5 ms in duration. 3) In another figure drawn both voltage and duration, it is interesting to know that the first group was subgrouped into two; the one is of short duration and high voltage and the other is of long duration and low voltage. In contrast to it, the latter was of low voltage and long duration. 4) In the r-s curve based on average discharge interval and standard deviation of its irregular variation of these spikes, the one of high voltage and short duration manifested a sharp increment and the other of low voltage and long duration, a slow increment. 5) Two types of such characteristic diphasic spikes were also obtained in M wave of provocation EMG. The latency appeared to be short in the spike of high voltage and short duration compared with the other. 6) The reflactory periods, both in absolute and relative, were also found to be short in the spike of high voltage and short duration incomparison with the other. 7) It is to be noted that the intermediate spike between these two types was found, although relatively in few incidence, both at voluntary contruction and in M wave at provocation. It seem to be concluded that the spike of high voltage and short duration corresponds with the one of kinetic NMU and the other, with the one of tonic NMU.
en-copyright=
kn-copyright=

en-aut-name=FujiiTakao
en-aut-sei=Fujii
en-aut-mei=Takao
kn-aut-name=藤井喬夫
kn-aut-sei=藤井
kn-aut-mei=喬夫
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=80
cd-vols=
no-issue=11-12
article-no=
start-page=1211
end-page=1222
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1968
dt-pub=19681230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Antimitotic Action of the Cornin, as a Biologically Active Polypeptide (�W)
kn-title=生物学的活性 Polypeptide "CORNIN" の細胞分裂に及ぼす影響（IV）
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The difference of the effect of cornins extracted from various kinds of living tissues was examined by employing several cell lines in vitro. And the inhibitory effect on tumor growth of the cornins was tested on the mice transplanted with Ehrlich ascites carcinoma. The results are as follows: 1) The antimitotic effect of canine intestine cornin (CIC) was more effective on Ehrlich ascites carcinoma cells in vitro (JTC-11) than that of bovine intestine cornin (BIC) and that of porcine intestine cornin (PIC). 2) Dialysable fraction, undialysable fraction and crude of CIC showed similar activities on the JTC-11 cell line. 3) The antigenicity of CIC was not proved by the hemagglutination test and no mice injected intraperitoneally with large doses of CIC showed any intoxication and disturbance. 4) The inhibitory effect of CIC on tumor growth was the strongest in the three kinds of the intestine cornins with Ehrlich ascites carcinoma and some of tumor-bearing mice were cured completly by the intraperitoneal injections of CIC. 5) The cornin extracted from liver of normal rats (RLC) had marked inhibitory effect on the cell growth of the short-term cultured cell line (RLM-1) and the long-term cultured cell line (RLN-10) originated from normal rat liver, but no effect was observed on the cell line in culture which came from the DAB ascites hepatoma of the same line rat.
en-copyright=
kn-copyright=

en-aut-name=KimotoKatsuhiko
en-aut-sei=Kimoto
en-aut-mei=Katsuhiko
kn-aut-name=木本克彦
kn-aut-sei=木本
kn-aut-mei=克彦
aut-affil-num=1
ORCID=

en-aut-name=FujitaTakashi
en-aut-sei=Fujita
en-aut-mei=Takashi
kn-aut-name=藤田興
kn-aut-sei=藤田
kn-aut-mei=興
aut-affil-num=2
ORCID=

en-aut-name=KobayashiYoshiji
en-aut-sei=Kobayashi
en-aut-mei=Yoshiji
kn-aut-name=小林芳治
kn-aut-sei=小林
kn-aut-mei=芳治
aut-affil-num=3
ORCID=

en-aut-name=TakahashiSeiichiro
en-aut-sei=Takahashi
en-aut-mei=Seiichiro
kn-aut-name=高橋誠一郎
kn-aut-sei=高橋
kn-aut-mei=誠一郎
aut-affil-num=4
ORCID=

en-aut-name=FujiiYoshinobu
en-aut-sei=Fujii
en-aut-mei=Yoshinobu
kn-aut-name=藤井義信
kn-aut-sei=藤井
kn-aut-mei=義信
aut-affil-num=5
ORCID=

en-aut-name=YamadaToshisuke
en-aut-sei=Yamada
en-aut-mei=Toshisuke
kn-aut-name=山田俊典
kn-aut-sei=山田
kn-aut-mei=俊典
aut-affil-num=6
ORCID=

en-aut-name=ChikataYoshiko
en-aut-sei=Chikata
en-aut-mei=Yoshiko
kn-aut-name=智片芳子
kn-aut-sei=智片
kn-aut-mei=芳子
aut-affil-num=7
ORCID=

en-aut-name=OhtsukiHisashi
en-aut-sei=Ohtsuki
en-aut-mei=Hisashi
kn-aut-name=大月恒
kn-aut-sei=大月
kn-aut-mei=恒
aut-affil-num=8
ORCID=

en-aut-name=MurakamiTetuhide
en-aut-sei=Murakami
en-aut-mei=Tetuhide
kn-aut-name=村上哲英
kn-aut-sei=村上
kn-aut-mei=哲英
aut-affil-num=9
ORCID=

en-aut-name=NisidaIsamu
en-aut-sei=Nisida
en-aut-mei=Isamu
kn-aut-name=西田勇
kn-aut-sei=西田
kn-aut-mei=勇
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=7
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=8
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=9
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=10
en-affil=
kn-affil=岡山大学医学部第一生理学教室
END

start-ver=1.4
cd-journal=joma
no-vol=82
cd-vols=
no-issue=11-12
article-no=
start-page=549
end-page=560
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1970
dt-pub=19701230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Regulation of Cell Division with
kn-title=筋肉コルニンの細胞分裂調節作用と，そのin vivo応用への基礎的研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The sterilizing effect and hemolytic effect of cornin, extracted from skeletal muscle of rabbit were studied in vivo and in vitro. The results are summarized as follows: 1. Muscle cornin has no effect whatever on sterility when administrated into new born mice and adult mice. 2. There is no difference on the period of pregnancy and on the new born numbers as compared with no treated control. 3. When the erythrocytes are incubated with muscle cornin and then transfered into the hypotonic salt solution, the hemolytic effect occurs below 0.7 per cent salt solution.
en-copyright=
kn-copyright=

en-aut-name=FujiiYoshinobu
en-aut-sei=Fujii
en-aut-mei=Yoshinobu
kn-aut-name=藤井義信
kn-aut-sei=藤井
kn-aut-mei=義信
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一生理学教室
END

start-ver=1.4
cd-journal=joma
no-vol=82
cd-vols=
no-issue=9-10
article-no=
start-page=417
end-page=420
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1970
dt-pub=19701030
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Heat stability of catalalase in acatalasemic anemic blood enhanced reticulocytes
kn-title=acatalasemiaマウス血液の網状赤血球と成熟赤血球に含まれるカタラーゼのheat stability acatalasemiaマウス血液の残余カタラーゼの研究，第一報
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In order to know the beat stability of catalse in non-acatalasemic and acatalasemic reticulocyte, phenylhydrazine anemia and depleted anemia were induced both in non-acataltasemic and acatalasemic mice. The hemolysates from anemic blood diluted ten times with distilled water were incubated at 44℃ for 10min., thereafter changes in catalase activity were determined. (1) Both in non-acatalsemic and acatalasemic mice, the heat stability of catalase in anemic blood containing about 50 per cent of reticulocyte is lower than that of catalase in non-anemic blood containing about 2 per cent of reticulocyte. (2) Catalase in anemic blood containing about 50 per cent of reticulocyte in acatalasemic mice is more unstable for heat than that in non-acatalasemic mice. In the case of non-anemic blood rich in erythrocytes, the similar results were obtaind. (3) From the results, it is recognized that the catalase in acatalasemic reticulocyte is more unstable for heat than that in non-acatalasemic reticulocyte, suggesting that the catalase in acatalasemic mouse blood has the structural changes due to the structural gene mutation.
en-copyright=
kn-copyright=

en-aut-name=FujiiToyoko
en-aut-sei=Fujii
en-aut-mei=Toyoko
kn-aut-name=藤井豊子
kn-aut-sei=藤井
kn-aut-mei=豊子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部公衆衛生学教室
END

start-ver=1.4
cd-journal=joma
no-vol=86
cd-vols=
no-issue=7-8
article-no=
start-page=385
end-page=392
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1974
dt-pub=19740830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on Fatty Acids Metabolism of Goldthioglucose Obese Mice �U. Metabolism of (U)-(14)C-Palmitic Acid, 1-(14)C-Linoleic Acid and 1-(14)C-γ-Linolenic Acid
kn-title=Goldthioglucose肥満マウスにおける脂酸代謝に関する研究 第2編 (U)-14C-palmitic acid, 1-14C-linoleic acidおよび1-14C-γ-linolenic acidの脂酸代謝について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Fatty acids synthesis from acetate in goldthioglucose obese (GTG) mice was described in part �T. In this report, the incorporation of (14)C from (U)-(14)C-palmitic acid, 1-(14)C-linoleic acid and 1-(14)C-γlinolenic acid into individual fatty acids and major lipid classes of liver was determined in vivo. Results were as follows. 1) No significant differences between GTG and control mice were found in the incorporation of (14)C into saponifiable fraction of lipids (total fatty acids) from (14)C-palmitic acid, (14)C-linoleic acid and (14)C-γ-linolenic acid. 2) In the percentage distribution of (14)C in malor lipid classes in both groups of mice, it was found that (14)C come from (14)C-palmitic acid was incorporated mainly into triglyceride, (14)C from (14)C-linoleic acid into triglyceride and phospholipids, and (14)C from (14)C-γ-linolenic acid. mainly into phospholipids. A few differences between. GTG and control mice were found in the percentage distribution of (14)C from (14)C-palmltic acid, (14)C-linoleic acid and (14)C-γ-linolenic acid in triglyceride and phospholipids. 3) In regard to the study on the incorporation of (14)C into individual fatty acids of saponifiable fraction of lipids, the percentage of (14)C recovered in palmitic acid from (14)C-palmitic acid more increased and that in stearic acid more decreased in GTG mice than in control mice. When (14)C-linoleic acid was used as precursor the percentage of (14)C recovered in linoleic acid was 55-62% and that in arachidonic acid was about 12% of 14C in total fatty acids, in both groups of mice. However, the percentage distribution of (14)C in γ-linolenic acid from (14)C-γ-linolenic acid was 10% and that in arachidonic acid was 46-58% , in both groups of mice. The rate of conversion from γ-linolenic acid to arachidonic acid more increased in GTG mice than control mice. 4) In regard to the esterification of individual fatty acids into major lipid classes, it was
found in both groups of mice that linoleic acid was more esterified into tryglyceride than into phospholipids, and arachidonic acid was esterified mainly into phospholipids. From these results, metabolism of palmitic acid and essential fatty acids in GTG mice is characterized by increased palmitic acid pool and increased ratio of the conversion from γ-linolenic acid to arachidonic acid.
en-copyright=
kn-copyright=

en-aut-name=FujiiYasuhisa
en-aut-sei=Fujii
en-aut-mei=Yasuhisa
kn-aut-name=藤井靖久
kn-aut-sei=藤井
kn-aut-mei=靖久
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第2内科学教室
END

start-ver=1.4
cd-journal=joma
no-vol=86
cd-vols=
no-issue=7-8
article-no=
start-page=369
end-page=383
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1974
dt-pub=19740830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on Fatty Acids Metabolism of Goldthioglucose Obese Mice �T. Fatty Acids Synthesis from 1-(14)C-Acetate
kn-title=Goldthioglucose肥満マウスにおける脂酸代謝に関する研究 策1編 1-(14)C-acetateよりの脂酸合成について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Injection of goldthioglucose (GTG) destroys the bilateral ventro-medial nucleus, the "satiety area" and gives rise to hypothalamic obesity in mice (abbreated later as GTG mice). A considerable number of papers have been published on lipid metabolism of liver and adipose tissue in these obese animal. However, little is known about individual fatty acids synthesis in GTG mice. In this report, the author disclosed the individual fatty acids synthesis of liver and adipose tissue in GTG mice. Observations were performed both in vitro and in vivo, with analysis of the incorporation and distribution of 1-(14)C-acetate in individual fatty acids of major lipid classes Results were as follows. Experiment on liver; 1) Liver of GTG mice incorporated significantly more 1-(14)C-acetate in saponifiable fraction of lipids (=total fatty acids) than liver of control mice did. 2) In regard to the study on the distribution of 1-(14)C-acetate in individual fatty acids separated by gaschromatography, the percentage of radioactivity recovered in oleic acid significantly increased in GTG mice. On the other hand, the percentage of radioactivity in fatty acids with retention time corresponding to arachidic acid or longer relatively decreased. 3) After four hours' incubation of liver with 1-(14)C-acetate in vitro, the percentage distribution of radioactivity recovered in triglyceride significantly increased in GTG mice comparedd with control mice. In vivo, the percentage distribution of radioactivity increased in liver triglyceride with time from one hour to four hours after administration of 1-(14)C-acetate in GTG mice. 4) It is conspicuous that the amount of radioactivity recovered in oleic acid of GTG mice was always significantly higher than in that of control mice, on analysis of (14)C distribution in individual fatty acids esterified into triglyceride, both in vitro and in vivo. The percentage distribution of (14)C in oleic acid of triglyceride in GTG mice was increasing with time up to four hours in vivo, too. 5) In individual fatty acids esterified into phospholipids, the percentage of (14)C found in oleic acid of GTG mice was also higher than in that of control mice. 6) In vitro, fasted animals incorporated less (14)C into total fatty acids than fed animals in both GTG and control mice and significant decrease was observed in the percentage of (14)C in myristic acid and palmitic acid.
Experiment on adipose tissue; There was a highly significant increase in the incorporation of (14)C into total fatty acids in the tissue of GTG mice compared with control mice. However, no significant differences were found in the percentage distribution of (14)C in major lipid classes nor in individual fatty acids of saponifiable fraction of lipids between both groups of mice. From these results, the author advocates a possibility that obesity of these animals is due to the increased synthesis of fatty acids and increaed accumulation of triglyceride esterified with oleic acid.
en-copyright=
kn-copyright=

en-aut-name=FujiiYasuhisa
en-aut-sei=Fujii
en-aut-mei=Yasuhisa
kn-aut-name=藤井靖久
kn-aut-sei=藤井
kn-aut-mei=靖久
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第2内科学教室
END

start-ver=1.4
cd-journal=joma
no-vol=88
cd-vols=
no-issue=11-12
article-no=
start-page=1039
end-page=1054
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1976
dt-pub=19761230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on treatment in lung cancer Part �U. Studies on cellular immunity in lung cancer: Changes in cellular immune responses of patients treated with chemotherapeutic and streptococcal agents
kn-title=肺癌の治療に関する臨床的研究 第2編 肺癌患者の細胞性免疫能に関する研究―癌化学療法症例におけるその経時的変動と溶連菌剤の効果について―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Cellular immunity in lung cancer was studied by means of lymphocyte transformation by phytohemagglutinin (PHA), purified protein derivative (PPD) skin test, absolute counts of peripheral lymphocytes and leucocyte migration inhibition test. The lymphocyte transformation by PHA was reduced in lung cancer patients in comparison with healthy controls, and correlated with the disease stage, but not with the histology type. The lymphocyte transformation became further depressed by cancer chemotherapy. PPD skin reaction or absolute counts of peripheral lymphocytes did not correlate with the disease stage. However, all the three tests correlated with the disease stage. Therefore, these tests appeared to be general indices of the immunologic status. Inhibition of leucocyte migration was demonstrated in about a half of the patients with lung cancer, but not in patients with other cancers or infectious lung diseases or in healthy controls. These findings suggest the presence of tumor-associated antigens in lung cancer. Concerning the effect of the streptococcal agent, OK-432, enhancement of the function of lymphocyte was observed in the parameters such as lymphocyte transformation by PHA, PPD skin test and leucocyte migration inhibition test. In addition, OK-432 yielded a longer survival in lung cancer patients when used in combination with chemotherapy than with chemotherapy alone.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasafumi
en-aut-sei=Fujii
en-aut-mei=Masafumi
kn-aut-name=藤井昌史
kn-aut-sei=藤井
kn-aut-mei=昌史
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第2内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=88
cd-vols=
no-issue=11-12
article-no=
start-page=1031
end-page=1038
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1976
dt-pub=19761230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on treatment in lung cancer Part �T. Studies on chemotherapy in advanced lung cancer: Combination chemotherapy with FOBEM (5-fluorouracil, vincristine, bleomycin, cyclophosphamide and mitomycin C)
kn-title=肺癌の治療に関する臨床的研究 第1編 進行肺癌の化学療法に関する研究―5-fluorouracil, vincristine, bleomycin, cyclophosphamide, mitomycin Cによる多剤併用（FOBEM）療法について―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A regimen consisting of 5-fluorouracil, vincristine, bleomycin, cyclophosphamide and mitomycin C (FOBEM) was used for the treatment of advanced lung cancer patients. 5-fluorouracil (250mg) was administered every other day. Vincristine (1mg), bleomycin (15mg), cyclophosphamide (400mg) and mitomycin C (4mg) were each administered once a week for six consecutive weeks. Fourteen (28.6%) of 49 evaluated patients had significant tumor regression and included two patients with small cell carcinoma who shows complete regression. Histological classification indicated 17.6% of adenocarcinoma, 35.3% of squamous cell carcinoma and 57.0% of anaplastic carcinoma. And 12.5% of patients were diagnosed cytologically or clinically. Patients responding to FOBEM survived about two times longer after the initiation of chemotherapy than non-responders, and the survival was slightly longer in patients treated with FOBEM than in those administered one or two of these drugs. In aged patients pulmonary toxicity of bleomycin was the major dose limiting factor rather than the mild myelosuppressive toxicity, and the cumulative pulmonary toxicity necessitated the reduction of this drug. This FOBEM regimen warrants further investigation in the management of small cell and squamous cell carcinoma of the lung.
en-copyright=
kn-copyright=

en-aut-name=FujiiMasafumi
en-aut-sei=Fujii
en-aut-mei=Masafumi
kn-aut-name=藤井昌史
kn-aut-sei=藤井
kn-aut-mei=昌史
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第2内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=88
cd-vols=
no-issue=1-2
article-no=
start-page=39
end-page=50
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1976
dt-pub=19760228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The effects of heavy metals on developing sea urchin eggs.
kn-title=ウニ卵の発生に及ぼす重金属の影響
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The effects of heavy metals, such as Hg, Pb, Cu, Cd, As, Sn, Cr, Mn, Ni and Zn on the two developing sea urchin eggs. Temnopleurus and Hemicentrotus were investigated. The results obtained were as follows. 1. The development of fertilized eggs was inhibited when embryos were exposed to 10(-6) M of HgCl(2) and CuCl(2) and to 10(-4) M of CrCl(2) and NiCl(2) in Herbst's artificial seawater from fertilization until the formation of the blastula larva. 2. Chlorate and acetate of heavy metals were dissolved in filtered seawater. The morphological differences of embryo were not observed until the formation of the pluteus larva in the two solutions. Inhibitory effects were observed when embryos were exposed to seawater at concentrations of 10(-7) M of Hg and Cu, to 10(-6) M of Cd, and to 10(-5) M of Pb, Ni and Zn. At a concentration of 10(-4) M of Cd there were no visible effects until the appearance of swimming blastula larva, but larva development was strongly inhibited at time of bonification from pluteus larva, and there was no further later development. In 10(-6) M Hg, Cr, and Ni, the larvae were structural abnonal and shaped like Apollo. In 10(-7) M of Hg exogastrula embryos were produced. 3. Threshold concentration of complete inhibition on the early development of sea urchin embryos was at 10(-6) M of Hg, 10(-5) M of Cu, Cr, Ni, and Zn, 10(-3) M of Mn. In the case of Cd 10(-5) M, complete inhibition didn't occur until the pluteus larva stage. 4. Only additive effects were obtained on the developing sea urchin eggs when two heavy metals were combined in filtered seawater. A high frequency of morphological abnormalities were formed such as exogastrula and Apollo shaped pluteus especially in coupling of Hg and Cu or Cd and Zn. 5. There were no visible effects in filtered sewage from fertilization to the formation of the pluteus larva. When embryos were exposed to acetate salts of Hg, Cu, Cd, and Zn in filtered sewage, there were 10 fold inhibitory effects on development. But formation of skeleton in the pluteus larva was found in filtered sewage containing Cd. 6. Only additive effects were observed on sea urchin embryo when combined with Hg, Cu, Cd, and Zn in filterd sewage. But the abnormalities were decreased in all cases. Inhibition of bonification were reduced in mixture of Cd and filtered sewage.
en-copyright=
kn-copyright=

en-aut-name=MurakamiTetuhide
en-aut-sei=Murakami
en-aut-mei=Tetuhide
kn-aut-name=村上哲英
kn-aut-sei=村上
kn-aut-mei=哲英
aut-affil-num=1
ORCID=

en-aut-name=HayakawaMasashi
en-aut-sei=Hayakawa
en-aut-mei=Masashi
kn-aut-name=早川昌志
kn-aut-sei=早川
kn-aut-mei=昌志
aut-affil-num=2
ORCID=

en-aut-name=FujiiToshitake
en-aut-sei=Fujii
en-aut-mei=Toshitake
kn-aut-name=藤井和武
kn-aut-sei=藤井
kn-aut-mei=和武
aut-affil-num=3
ORCID=

en-aut-name=HaraTakehito
en-aut-sei=Hara
en-aut-mei=Takehito
kn-aut-name=原武仁
kn-aut-sei=原
kn-aut-mei=武仁
aut-affil-num=4
ORCID=

en-aut-name=ItamiYoshiaki
en-aut-sei=Itami
en-aut-mei=Yoshiaki
kn-aut-name=伊丹義明
kn-aut-sei=伊丹
kn-aut-mei=義明
aut-affil-num=5
ORCID=

en-aut-name=KishidaAkira
en-aut-sei=Kishida
en-aut-mei=Akira
kn-aut-name=岸田昭
kn-aut-sei=岸田
kn-aut-mei=昭
aut-affil-num=6
ORCID=

en-aut-name=NisidaIsamu
en-aut-sei=Nisida
en-aut-mei=Isamu
kn-aut-name=西田勇
kn-aut-sei=西田
kn-aut-mei=勇
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部第一生理学教室

affil-num=7
en-affil=
kn-affil=岡山大学医学部第一生理学教室
END

start-ver=1.4
cd-journal=joma
no-vol=87
cd-vols=
no-issue=7-8
article-no=
start-page=661
end-page=671
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1975
dt-pub=19750831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Statistical study on tympanoplasty and postoperative hearing gain. -Observations of cases operated for the past 10 years (1963-1972) in the Dept. of Otolaryngology, Okayama University-
kn-title=岡山大耳鼻科教室における鼓室成形術の統計と術後聴力―昭和38‐47年の間の手術に関して―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=(1) Tympanoplasties were done on 956 ears (789 persons) in our clinic for the past 10 years. (2) 684 operated ears of ages 10 to 29 were 72% in age distribution. (3) In 956 operated ears, the primary operations were 633 and the reoperations were 323. The rate of success of the hearing gain after surgery was 48.7% in the primary operation and was 44.4% in the reoperation. (4) In the primary operation, the conservative type (Wullstein �T and �U types) was done on 60.5% and its rate of success of hearing gain after surgery was 61.9%. The rate of success
of hearing gain after surgery was 29.5% of the radical type group (Wullstein �V and �W types, and modified types). (5) In the reoperation, the conservative type group was done on 29.1%, and its rate of success of hearing gain was 73.0%. The rate of success of hearing gain was 31.3% of the radical type group. (6) As the materials forming the tympanic membrane in the primary operation, the meatal skin flaps were used on 41.3%, the temporal fascia grafts were 35.1%, the thigh skin grafts were 12.8%, the double grafting were 9.8%. The rate of success of hearing gain after surgery was from 55.3% to 48.4% in the temporal fascia graft, meatal skin flap and double grafting, and was 28.0% in the thigh skin graft. In the reoperation, the meatal skin flaps were used on 52.3%, the thigh skin grafts were 17.3%, the double grafting were 15.1%, the temporal fascia graft were 14.6%. The rate of success of hearing gain after surgery was 81.3% in the double grafting, 68.4% in the temporal fascia graft, 32.8% in the meatel skin graft, 28.6% in the thigh skin graft. (7) As the materials of columella of the modified �V and �W types in the primary operation, the ossicles were used on 76.3%, the tragal cartilage were on 14.4%. The rate of success of hearing gain after surgery was 41.7% in the tragal cartilage, 27.1% in the ossicles. In the reoperation, the ossicles were used on 36.3%, the tragal caltilage were 40.8%. The rate of success of hearing gain after suergery was 46.2% in ossicles, 42.9% in the tragal cartilage. (8) The closed method was done on 44.7% in the primary operation and 8.4% in the reoperation. On the postoperative situation, the closed method were superior to the open method. (9) The operation technique was described, which was considered to be the most preferable at preset in our clinic.
en-copyright=
kn-copyright=

en-aut-name=KonishiShizuo
en-aut-sei=Konishi
en-aut-mei=Shizuo
kn-aut-name=小西静雄
kn-aut-sei=小西
kn-aut-mei=静雄
aut-affil-num=1
ORCID=

en-aut-name=TanakaTohru
en-aut-sei=Tanaka
en-aut-mei=Tohru
kn-aut-name=田中徹
kn-aut-sei=田中
kn-aut-mei=徹
aut-affil-num=2
ORCID=

en-aut-name=MikiMasami
en-aut-sei=Miki
en-aut-mei=Masami
kn-aut-name=三木正己
kn-aut-sei=三木
kn-aut-mei=正己
aut-affil-num=3
ORCID=

en-aut-name=KurokawaKyoko
en-aut-sei=Kurokawa
en-aut-mei=Kyoko
kn-aut-name=黒川恭子
kn-aut-sei=黒川
kn-aut-mei=恭子
aut-affil-num=4
ORCID=

en-aut-name=ShibataShiro
en-aut-sei=Shibata
en-aut-mei=Shiro
kn-aut-name=柴田四郎
kn-aut-sei=柴田
kn-aut-mei=四郎
aut-affil-num=5
ORCID=

en-aut-name=FujiiShizue
en-aut-sei=Fujii
en-aut-mei=Shizue
kn-aut-name=藤井静江
kn-aut-sei=藤井
kn-aut-mei=静江
aut-affil-num=6
ORCID=

en-aut-name=FujimuraAkiko
en-aut-sei=Fujimura
en-aut-mei=Akiko
kn-aut-name=藤本明子
kn-aut-sei=藤本
kn-aut-mei=明子
aut-affil-num=7
ORCID=

en-aut-name=OguraYoshio
en-aut-sei=Ogura
en-aut-mei=Yoshio
kn-aut-name=小倉義郎
kn-aut-sei=小倉
kn-aut-mei=義郎
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=川崎医科大学耳鼻咽喉科学教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部耳鼻咽喉科学教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部耳鼻咽喉科学教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部耳鼻咽喉科学教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部耳鼻咽喉科学教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部耳鼻咽喉科学教室

affil-num=7
en-affil=
kn-affil=岡山大学医学部耳鼻咽喉科学教室

affil-num=8
en-affil=
kn-affil=岡山大学医学部耳鼻咽喉科学教室
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2009
dt-pub=20090930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=先天性チアノーゼラットにおける心虚血再還流障害抵抗性の検討
kn-title=Tolerance of the developing cyanotic heart to ischemia-reperfusion injury in the rat
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiiYasuhiro
en-aut-sei=Fujii
en-aut-mei=Yasuhiro
kn-aut-name=藤井泰宏
kn-aut-sei=藤井
kn-aut-mei=泰宏
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=121
cd-vols=
no-issue=3
article-no=
start-page=169
end-page=171
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2009
dt-pub=20091201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A retrospective study of the PROLENE hernia system comparedwith the mesh-plug technique
kn-title=成人鼠径ヘルニア手術症例の臨床的検討：Mesh plug 法と PROLENE hernia system の比較
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=To compare the results of the PROLENE hernia system (PHS) and mesh-plug technique (MPT), a retrospective study of adult patients with inguinal hernia was performed. The total number of inguinal herniorrhaphies for the past 9 years was 376, and the numbers of operative treatments by PHS, MPT and the Bassini procedure were 79, 291 and 6, respectively. There were no significant differences either in the operating time or the hospitalization days. No postoperative complications were observed in the PHS group; however, 8 complications were found among the 291 cases (2.75 %) of the MPT group (hematoma, 3 ; seroma, 2 ; testitis, 1 ; mesh infection, 2). Out of the total 376 cases, the number of initial and recurrence cases was 355 and 21, respectively, and out of the 21 recurrence cases the number of initial surgeries by Bassini and MPT was 14 and 7, respectively. Among the 21 recurrence cases there were no recurrences after PHS.
en-copyright=
kn-copyright=

en-aut-name=HamanoRyosuke
en-aut-sei=Hamano
en-aut-mei=Ryosuke
kn-aut-name=濱野亮輔
kn-aut-sei=濱野
kn-aut-mei=亮輔
aut-affil-num=1
ORCID=

en-aut-name=OhtsukaShinya
en-aut-sei=Ohtsuka
en-aut-mei=Shinya
kn-aut-name=大塚眞哉
kn-aut-sei=大塚
kn-aut-mei=眞哉
aut-affil-num=2
ORCID=

en-aut-name=FujiiSayaka
en-aut-sei=Fujii
en-aut-mei=Sayaka
kn-aut-name=藤井清香
kn-aut-sei=藤井
kn-aut-mei=清香
aut-affil-num=3
ORCID=

en-aut-name=NishieManabu
en-aut-sei=Nishie
en-aut-mei=Manabu
kn-aut-name=西江学
kn-aut-sei=西江
kn-aut-mei=学
aut-affil-num=4
ORCID=

en-aut-name=TokunagaNaoyuki
en-aut-sei=Tokunaga
en-aut-mei=Naoyuki
kn-aut-name=徳永尚之
kn-aut-sei=徳永
kn-aut-mei=尚之
aut-affil-num=5
ORCID=

en-aut-name=TsunemitsuYosuke
en-aut-sei=Tsunemitsu
en-aut-mei=Yosuke
kn-aut-name=常光洋輔
kn-aut-sei=常光
kn-aut-mei=洋輔
aut-affil-num=6
ORCID=

en-aut-name=IwakawaKazuhide
en-aut-sei=Iwakawa
en-aut-mei=Kazuhide
kn-aut-name=岩川和秀
kn-aut-sei=岩川
kn-aut-mei=和秀
aut-affil-num=7
ORCID=

en-aut-name=InagakiMasaru
en-aut-sei=Inagaki
en-aut-mei=Masaru
kn-aut-name=稲垣優
kn-aut-sei=稲垣
kn-aut-mei=優
aut-affil-num=8
ORCID=

en-aut-name=OhsakiToshihide
en-aut-sei=Ohsaki
en-aut-mei=Toshihide
kn-aut-name=大崎俊英
kn-aut-sei=大崎
kn-aut-mei=俊英
aut-affil-num=9
ORCID=

en-aut-name=IwagakiHiromi
en-aut-sei=Iwagaki
en-aut-mei=Hiromi
kn-aut-name=岩垣博巳
kn-aut-sei=岩垣
kn-aut-mei=博巳
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=独立行政法人国立病院機構福山医療センター　外科

affil-num=2
en-affil=
kn-affil=独立行政法人国立病院機構福山医療センター　外科

affil-num=3
en-affil=
kn-affil=独立行政法人国立病院機構福山医療センター　外科

affil-num=4
en-affil=
kn-affil=独立行政法人国立病院機構福山医療センター　外科

affil-num=5
en-affil=
kn-affil=独立行政法人国立病院機構福山医療センター　外科

affil-num=6
en-affil=
kn-affil=独立行政法人国立病院機構福山医療センター　外科

affil-num=7
en-affil=
kn-affil=独立行政法人国立病院機構福山医療センター　外科

affil-num=8
en-affil=
kn-affil=独立行政法人国立病院機構福山医療センター　外科

affil-num=9
en-affil=
kn-affil=独立行政法人国立病院機構福山医療センター　外科

affil-num=10
en-affil=
kn-affil=独立行政法人国立病院機構福山医療センター　外科
en-keyword=鼠径ヘルニア (inguinal hernia)
kn-keyword=鼠径ヘルニア (inguinal hernia)
en-keyword=mesh plug 法 (mesh plug technique)
kn-keyword=mesh plug 法 (mesh plug technique)
en-keyword=PROLENE hernia system
kn-keyword=PROLENE hernia system
END

start-ver=1.4
cd-journal=joma
no-vol=89
cd-vols=
no-issue=7-8
article-no=
start-page=883
end-page=894
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19770830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Co-existence of inhibitory and stimulatory factors on cell proliferation in a same rat liver supernatant and their regenerating changes
kn-title=ラット肝上清中に共存せる細胞増殖抑制因子と促進因子の肝再生誘導による活性変換について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Responding mechanism of regenerating hepatocytes induced by partial hepatectomy was studied. 1) Fibroblast inhibitory and stimulatory factors on fibroblast proliferation co-exist in the same rat liver supernatant, and they were simply isolated each other by ethanol fractionation. 2) These factors have protein components and lose the biological activities by heat-treatment, and they show the competitive activity each other, respectively. 3) In regenerating liver, stimulatory factor(s) was not remarkably changed, but inhibitory one almost lost the inhibitory activity. These phenomena are very rational and suitable for hepatocyte regeneration. 4) The inhibitory activity was separatedly eluted by DEAE-cellulose chromatography of inactive regenerating liver fraction, and new peak that did not exist in normal inhibitory fraction was detected in polyacrylamid gel electrophoresis of regenerating liver same fraction. 5) These phenomena suggest that a possible new anti-inhibitory factor(s) would be formed by partial hepatectomy.
en-copyright=
kn-copyright=

en-aut-name=FujiiToshitake
en-aut-sei=Fujii
en-aut-mei=Toshitake
kn-aut-name=藤井利武
kn-aut-sei=藤井
kn-aut-mei=利武
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一生理学教室
END

start-ver=1.4
cd-journal=joma
no-vol=92
cd-vols=
no-issue=9-10
article-no=
start-page=1045
end-page=1053
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1980
dt-pub=19801030
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Paroxysmal atrial fibrillation
kn-title=発作性心房細動について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Out of 60 patients of transient atrial fibrillation including a case followed up for 12 years, 51 cases with unknown etiology or due to ischemic heart disease were studied in this paper. 1. Transient atrial fibrillation tends to induce cerebrovascular accidents although no direct relationship between the two was detected. 2. Transient atrial fibrillation combines frequently with sick sinus syndrome, especially with sinus bradycardia. 3. The cases combined with sick sinus syndrome have not only cardiac problems but also a higher risk of cerebrovascular accidents. 4. At the onset of atrial fibrillation, many cases complain of pollakisuria as well as other symptoms reported previously. 5. No apparent causes for atrial fibrillation was found in more than half of our cases. However, most cases had something to do with physical and/or mental stress.
en-copyright=
kn-copyright=

en-aut-name=MaeRitsuo
en-aut-sei=Mae
en-aut-mei=Ritsuo
kn-aut-name=前律夫
kn-aut-sei=前
kn-aut-mei=律夫
aut-affil-num=1
ORCID=

en-aut-name=NagahanaHaruki
en-aut-sei=Nagahana
en-aut-mei=Haruki
kn-aut-name=長花晴樹
kn-aut-sei=長花
kn-aut-mei=晴樹
aut-affil-num=2
ORCID=

en-aut-name=MashimaKozo
en-aut-sei=Mashima
en-aut-mei=Kozo
kn-aut-name=間嶋行造
kn-aut-sei=間嶋
kn-aut-mei=行造
aut-affil-num=3
ORCID=

en-aut-name=FujiiAkinobu
en-aut-sei=Fujii
en-aut-mei=Akinobu
kn-aut-name=藤井章伸
kn-aut-sei=藤井
kn-aut-mei=章伸
aut-affil-num=4
ORCID=

en-aut-name=IhoriyaKazuo
en-aut-sei=Ihoriya
en-aut-mei=Kazuo
kn-aut-name=庵谷和夫
kn-aut-sei=庵谷
kn-aut-mei=和夫
aut-affil-num=5
ORCID=

en-aut-name=SaitoDaiji
en-aut-sei=Saito
en-aut-mei=Daiji
kn-aut-name=斎藤大治
kn-aut-sei=斎藤
kn-aut-mei=大治
aut-affil-num=6
ORCID=

en-aut-name=HaraokaShoichi
en-aut-sei=Haraoka
en-aut-mei=Shoichi
kn-aut-name=原岡昭一
kn-aut-sei=原岡
kn-aut-mei=昭一
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=7
en-affil=
kn-affil=岡山大学医学部第一内科教室
en-keyword=発作性心房細動
kn-keyword=発作性心房細動
en-keyword=Sick Sinus Syndrome
kn-keyword=Sick Sinus Syndrome
en-keyword=脳血管障害
kn-keyword=脳血管障害
en-keyword=頻尿
kn-keyword=頻尿
END

start-ver=1.4
cd-journal=joma
no-vol=92
cd-vols=
no-issue=9-10
article-no=
start-page=1033
end-page=1044
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1980
dt-pub=19801030
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Tricuspid incompetence due to non-penetrating trauma with a congenital left pleuro-pericardial defect
kn-title=左側心外膜欠損を伴つた外傷性三尖弁閉鎖不全症の1例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We report a case of traumatic rupture of the chordae tendineae of the tricuspid valve with a congenital left pleuro-pericardial defect. The chest X ray film revealed a large cardiac silhouette which protruded to the left. Echocardiographic findings were: 1) large right ventricle and paradoxical septal motion 2) tricuspid regurgitatin which was recognized by contrast echocardiography 3) small left ventricle. This case also had a characteristic finding of systolic fine oscillation on the posterior tricuspid leaflet. Computed tomograms explained the discrepancy (protrusion to the left in chest X ray and small left ventricle): Computed tomograms of the heart revealed an enlarged right atrium and right ventricle associated with prominent clockwise rotation of the heart. Open heart surgery, performed successfully 16 years after the non-penetrating trauma, revealed the congenital pericardial defect which produced the findings of computed tomogram.
en-copyright=
kn-copyright=

en-aut-name=HaraokaShoichi
en-aut-sei=Haraoka
en-aut-mei=Shoichi
kn-aut-name=原岡昭一
kn-aut-sei=原岡
kn-aut-mei=昭一
aut-affil-num=1
ORCID=

en-aut-name=UedaMinoru
en-aut-sei=Ueda
en-aut-mei=Minoru
kn-aut-name=上田稔
kn-aut-sei=上田
kn-aut-mei=稔
aut-affil-num=2
ORCID=

en-aut-name=YamadaNobuyuki
en-aut-sei=Yamada
en-aut-mei=Nobuyuki
kn-aut-name=山田信行
kn-aut-sei=山田
kn-aut-mei=信行
aut-affil-num=3
ORCID=

en-aut-name=NagahanaHaruki
en-aut-sei=Nagahana
en-aut-mei=Haruki
kn-aut-name=長花晴樹
kn-aut-sei=長花
kn-aut-mei=晴樹
aut-affil-num=4
ORCID=

en-aut-name=IhoriyaKazuo
en-aut-sei=Ihoriya
en-aut-mei=Kazuo
kn-aut-name=庵谷和夫
kn-aut-sei=庵谷
kn-aut-mei=和夫
aut-affil-num=5
ORCID=

en-aut-name=MashimaKozo
en-aut-sei=Mashima
en-aut-mei=Kozo
kn-aut-name=間嶋行造
kn-aut-sei=間嶋
kn-aut-mei=行造
aut-affil-num=6
ORCID=

en-aut-name=FujiiAkinobu
en-aut-sei=Fujii
en-aut-mei=Akinobu
kn-aut-name=藤井章伸
kn-aut-sei=藤井
kn-aut-mei=章伸
aut-affil-num=7
ORCID=

en-aut-name=SaitoDaiji
en-aut-sei=Saito
en-aut-mei=Daiji
kn-aut-name=斎藤大治
kn-aut-sei=斎藤
kn-aut-mei=大治
aut-affil-num=8
ORCID=

en-aut-name=TeramotoShigeru
en-aut-sei=Teramoto
en-aut-mei=Shigeru
kn-aut-name=寺本滋
kn-aut-sei=寺本
kn-aut-mei=滋
aut-affil-num=9
ORCID=

en-aut-name=NawaKiyoto
en-aut-sei=Nawa
en-aut-mei=Kiyoto
kn-aut-name=名和清人
kn-aut-sei=名和
kn-aut-mei=清人
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=7
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=8
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=9
en-affil=
kn-affil=岡山大学医学部第二外科教室

affil-num=10
en-affil=
kn-affil=岡山大学医学部第二外科教室
en-keyword=非穿通性心外傷
kn-keyword=非穿通性心外傷
en-keyword=三尖弁閉鎖不全症
kn-keyword=三尖弁閉鎖不全症
en-keyword=心胸膜欠損
kn-keyword=心胸膜欠損
en-keyword=心エコー図と胸部CT
kn-keyword=心エコー図と胸部CT
END

start-ver=1.4
cd-journal=joma
no-vol=92
cd-vols=
no-issue=5-6
article-no=
start-page=629
end-page=633
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1980
dt-pub=19800630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Inverse relationship between heart rate and myocardial oxygen consumption per beat
kn-title=心拍数と心筋酸素消費量 ―1心拍当りの心筋酸素消費量と心拍数の関係―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Relationship between heart rate and myocardial oxygen consumption per beat was studied in anesthetized open-chest dogs. Myocardial oxygen consumption per minute (MVO(2)) was calculated as the product of the left coronary artery blood flow and coronary arterio-venous oxygen difference. Myocardial oxygen consumption per beat (MVO(2)-Beat) was the quotient of MVO(2) divided by heart rate (HR). HR was varied in 78-210 beats/min with left atrial pacing. Systemic arterial and left ventricular enddiastolic pressure were kept constant, and arterial blood gases were within physiological ranges. Although MVO(2) correlated significantly with HR (r=0.71), MVO(2)-Beat decreased in association with an increase in heart rate. Closer relationship was observed between MVO(2)-Beat and HR; MVO(2)-Beat (ml/100g LV muscle)= -0.00036 + 0.13, r= -0.86, P<0.001. As the results, MVO(2) was represented as a quadratic equation of HR; MVO(2) (ml/min/100g LV muscle)= -0.00036HR(2) + 0.13HR. There was a good correlation (r=0.88) between MVO(2)-Beat and the area under a stroke left ventricular pressure curve. This finding and constant systemic arterial and left ventricular pressure suggest that the inverse relationship between MVO(2)-Beat and HR is mainly due to a reduction in duration of systolic left ventricular wall tension.
en-copyright=
kn-copyright=

en-aut-name=HaraokaShoichi
en-aut-sei=Haraoka
en-aut-mei=Shoichi
kn-aut-name=原岡昭一
kn-aut-sei=原岡
kn-aut-mei=昭一
aut-affil-num=1
ORCID=

en-aut-name=SaitoDaiji
en-aut-sei=Saito
en-aut-mei=Daiji
kn-aut-name=斉藤大治
kn-aut-sei=斉藤
kn-aut-mei=大治
aut-affil-num=2
ORCID=

en-aut-name=IhoriyaKazuo
en-aut-sei=Ihoriya
en-aut-mei=Kazuo
kn-aut-name=庵谷和夫
kn-aut-sei=庵谷
kn-aut-mei=和夫
aut-affil-num=3
ORCID=

en-aut-name=NagahanaHaruki
en-aut-sei=Nagahana
en-aut-mei=Haruki
kn-aut-name=長花晴樹
kn-aut-sei=長花
kn-aut-mei=晴樹
aut-affil-num=4
ORCID=

en-aut-name=FujiiAkinobu
en-aut-sei=Fujii
en-aut-mei=Akinobu
kn-aut-name=藤井章伸
kn-aut-sei=藤井
kn-aut-mei=章伸
aut-affil-num=5
ORCID=

en-aut-name=MashimaIkuzo
en-aut-sei=Mashima
en-aut-mei=Ikuzo
kn-aut-name=間嶋行造
kn-aut-sei=間嶋
kn-aut-mei=行造
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部第一内科教室
en-keyword=心拍数
kn-keyword=心拍数
en-keyword=心筋酸素消費量
kn-keyword=心筋酸素消費量
en-keyword=左室内圧
kn-keyword=左室内圧
en-keyword=収縮時間
kn-keyword=収縮時間
END

start-ver=1.4
cd-journal=joma
no-vol=92
cd-vols=
no-issue=5-6
article-no=
start-page=613
end-page=627
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1980
dt-pub=19800630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Cardiac sympathetic nerve stimulation and electrocardiographic changes in the closed-chest dog
kn-title=心臓交感神経刺激による心電図変化 (実験的検討)
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Electrocardiographic and vectorcardiographic changes in Frank's corrected orthogonal lead system were studied stimulating electrically the right stellate ganglion (RSG), the left stellate ganglion (LSG) and both stellate ganglia (LSG+RSG) in anesthetized closed-chest dogs. The effects of propranolol on arrhythmias induced by the stimulation of the cardiac sympathetic nerve were also investigated. The following results were obtained: (1) The amplitude of T wave increased in Y lead with simultaneous stimulation of both right and left stellate ganglia. The spatial maximum T vector was displaced inferiorly and increased in the magnitude in all cases. These electrocardiographic changes were similar to those which occurred with LSG stimulation alone. (2) The rotation of the T loop, in the left sagital plane, was clockwise in more than 80% with RSG stimulation, while the T loop following the stimulation of LSG alone and LSG+RSG rotated counterclockwise in more than 75% of all cases. (3) In more than 40% of cases with stimulation of left cardiac sympathetic nerves (LSG, left ventrolateral cervical cardiac nerve), arrhythmias such as A-V dissociation and A-V junctional rhythm were recognized. Stimulation of right cardiac sympathetic nerve (RSG, right recurrent cardiac nerve) markedly increased the rate of sinus rhythm in more than 90% of cases. These arrhythmias resulted from the stimulation of nerves decreased or disappeared after the intravenous injection of propranolol.
en-copyright=
kn-copyright=

en-aut-name=HaraokaShoichi
en-aut-sei=Haraoka
en-aut-mei=Shoichi
kn-aut-name=原岡昭一
kn-aut-sei=原岡
kn-aut-mei=昭一
aut-affil-num=1
ORCID=

en-aut-name=YoshidaHidenori
en-aut-sei=Yoshida
en-aut-mei=Hidenori
kn-aut-name=吉田英紀
kn-aut-sei=吉田
kn-aut-mei=英紀
aut-affil-num=2
ORCID=

en-aut-name=IhoriyaKazuo
en-aut-sei=Ihoriya
en-aut-mei=Kazuo
kn-aut-name=庵谷和夫
kn-aut-sei=庵谷
kn-aut-mei=和夫
aut-affil-num=3
ORCID=

en-aut-name=KusachiShowzo
en-aut-sei=Kusachi
en-aut-mei=Showzo
kn-aut-name=草地省蔵
kn-aut-sei=草地
kn-aut-mei=省蔵
aut-affil-num=4
ORCID=

en-aut-name=NishiyamaOsamu
en-aut-sei=Nishiyama
en-aut-mei=Osamu
kn-aut-name=西山修
kn-aut-sei=西山
kn-aut-mei=修
aut-affil-num=5
ORCID=

en-aut-name=YasuharaKoichiro
en-aut-sei=Yasuhara
en-aut-mei=Koichiro
kn-aut-name=安原耕一郎
kn-aut-sei=安原
kn-aut-mei=耕一郎
aut-affil-num=6
ORCID=

en-aut-name=YamadaNobuyuki
en-aut-sei=Yamada
en-aut-mei=Nobuyuki
kn-aut-name=山田信行
kn-aut-sei=山田
kn-aut-mei=信行
aut-affil-num=7
ORCID=

en-aut-name=SogoTaiji
en-aut-sei=Sogo
en-aut-mei=Taiji
kn-aut-name=十河泰司
kn-aut-sei=十河
kn-aut-mei=泰司
aut-affil-num=8
ORCID=

en-aut-name=FujiiAkinobu
en-aut-sei=Fujii
en-aut-mei=Akinobu
kn-aut-name=藤井章伸
kn-aut-sei=藤井
kn-aut-mei=章伸
aut-affil-num=9
ORCID=

en-aut-name=UedaMinoru
en-aut-sei=Ueda
en-aut-mei=Minoru
kn-aut-name=上田稔
kn-aut-sei=上田
kn-aut-mei=稔
aut-affil-num=10
ORCID=

en-aut-name=SaitoDaiji
en-aut-sei=Saito
en-aut-mei=Daiji
kn-aut-name=斉藤大治
kn-aut-sei=斉藤
kn-aut-mei=大治
aut-affil-num=11
ORCID=

en-aut-name=HisamatsuMitsuo
en-aut-sei=Hisamatsu
en-aut-mei=Mitsuo
kn-aut-name=久松三生
kn-aut-sei=久松
kn-aut-mei=三生
aut-affil-num=12
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=7
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=8
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=9
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=10
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=11
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=12
en-affil=
kn-affil=岡山大学医学部第一内科教室
en-keyword=心臓交感神経刺激
kn-keyword=心臓交感神経刺激
en-keyword=Ｔ波（大きさ,回転）
kn-keyword=Ｔ波（大きさ,回転）
en-keyword=不整脈
kn-keyword=不整脈
en-keyword=心拍数
kn-keyword=心拍数
en-keyword=ベクトル心電図
kn-keyword=ベクトル心電図
END

start-ver=1.4
cd-journal=joma
no-vol=92
cd-vols=
no-issue=3-4
article-no=
start-page=455
end-page=461
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1980
dt-pub=19800430
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An autopsy case of liver cirrhosis with hepatic encephalopathy and intracranial bleeding
kn-title=肝性脳症慢性型を呈する肝硬変症にみられた頭蓋内出血の1剖検例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Bloody cerebrospinal fluid indicated that the neuropsychiatric abnormalities observed in a cirrhotic patient with a chronic type of hepatic encephalopathy were due to intracranial vascular lesions. Autopsy findings revealed hemorrhagic infarction at the left frontal pole and subarachinoideal bleeding at the occipital lobe. It is particularly important to realize that abnormal mental states occurring in patients with cirrhosis of the liver may be due to many other conditions leading to coma.
en-copyright=
kn-copyright=

en-aut-name=WatanabeAkiharu
en-aut-sei=Watanabe
en-aut-mei=Akiharu
kn-aut-name=渡辺明治
kn-aut-sei=渡辺
kn-aut-mei=明治
aut-affil-num=1
ORCID=

en-aut-name=IzumiMasaki
en-aut-sei=Izumi
en-aut-mei=Masaki
kn-aut-name=泉正樹
kn-aut-sei=泉
kn-aut-mei=正樹
aut-affil-num=2
ORCID=

en-aut-name=MizutaniShigeki
en-aut-sei=Mizutani
en-aut-mei=Shigeki
kn-aut-name=水谷繁樹
kn-aut-sei=水谷
kn-aut-mei=繁樹
aut-affil-num=3
ORCID=

en-aut-name=FujiiToshitake
en-aut-sei=Fujii
en-aut-mei=Toshitake
kn-aut-name=藤井利武
kn-aut-sei=藤井
kn-aut-mei=利武
aut-affil-num=4
ORCID=

en-aut-name=WatanabeMasahiro
en-aut-sei=Watanabe
en-aut-mei=Masahiro
kn-aut-name=渡辺正博
kn-aut-sei=渡辺
kn-aut-mei=正博
aut-affil-num=5
ORCID=

en-aut-name=HigashiToshihiro
en-aut-sei=Higashi
en-aut-mei=Toshihiro
kn-aut-name=東俊宏
kn-aut-sei=東
kn-aut-mei=俊宏
aut-affil-num=6
ORCID=

en-aut-name=YoshidaHideki
en-aut-sei=Yoshida
en-aut-mei=Hideki
kn-aut-name=吉田英紀
kn-aut-sei=吉田
kn-aut-mei=英紀
aut-affil-num=7
ORCID=

en-aut-name=EndoHiroshi
en-aut-sei=Endo
en-aut-mei=Hiroshi
kn-aut-name=遠藤浩
kn-aut-sei=遠藤
kn-aut-mei=浩
aut-affil-num=8
ORCID=

en-aut-name=NagashimaHideo
en-aut-sei=Nagashima
en-aut-mei=Hideo
kn-aut-name=長島秀夫
kn-aut-sei=長島
kn-aut-mei=秀夫
aut-affil-num=9
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=7
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=8
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=9
en-affil=
kn-affil=岡山大学医学部第一内科学教室
en-keyword=肝性脳症慢性型
kn-keyword=肝性脳症慢性型
en-keyword=肝硬変
kn-keyword=肝硬変
en-keyword=頭蓋内出血
kn-keyword=頭蓋内出血
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=7-8
article-no=
start-page=717
end-page=727
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Electrocardiographic changes after neurosurgery
kn-title=脳外科手術前後における心電図変化
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Electrocardiograms (ECG) and laboratory data were studied in 130 neurosurgical patients before and after neurosurgery. The following results were obtained: 1. The postoperative ECG showed ST-T changes in 21 % of the cases with subarachnoid hemorrhage, 15 % with cerebral tumor, 37.5 % with supracellar tumor and 50 % with Parkinson syndrome. 2. In 50 % of subarachnoid hemorrhage and 47 % of cerebral tumor, postoperative ECG deteriorated within 1 week. After 2 weeks such deterioration was observed in only 37 % in the former cases and 43 % in the latter. 3. Postoperative ECGs were improved or unchanged in 83 % cases of cerebral bleeding, 75 % (within 1 week) and 83 % (after 2 weeks) of intracerebral bleeding, and in all of Parkinson syndrome. However, in the cases of supra-cellar tumor, postoperative ECGs deteriorated 100 % within 1 week and 75 % after 2 weeks. 4. Serum K(+) and Ca(++) were decreased significantly in the group with deteriorated postoperative ECGs. The R. B. C., Hb and Ht were decreased regardless of postoperative ECGs. 5. Postoperative ECGs deteriorated when the operation time lasted longer than 6 h or blood loss during the operation was over 1,000 ml.
en-copyright=
kn-copyright=

en-aut-name=YoshidaHidenori
en-aut-sei=Yoshida
en-aut-mei=Hidenori
kn-aut-name=吉田英紀
kn-aut-sei=吉田
kn-aut-mei=英紀
aut-affil-num=1
ORCID=

en-aut-name=SaitoDaiji
en-aut-sei=Saito
en-aut-mei=Daiji
kn-aut-name=斉藤大治
kn-aut-sei=斉藤
kn-aut-mei=大治
aut-affil-num=2
ORCID=

en-aut-name=HyodoTazuo
en-aut-sei=Hyodo
en-aut-mei=Tazuo
kn-aut-name=兵頭多津男
kn-aut-sei=兵頭
kn-aut-mei=多津男
aut-affil-num=3
ORCID=

en-aut-name=NishiharaMasanobu
en-aut-sei=Nishihara
en-aut-mei=Masanobu
kn-aut-name=西原正信
kn-aut-sei=西原
kn-aut-mei=正信
aut-affil-num=4
ORCID=

en-aut-name=UchidaToshiaki
en-aut-sei=Uchida
en-aut-mei=Toshiaki
kn-aut-name=内田俊明
kn-aut-sei=内田
kn-aut-mei=俊明
aut-affil-num=5
ORCID=

en-aut-name=KimuraMasashi
en-aut-sei=Kimura
en-aut-mei=Masashi
kn-aut-name=木村正司
kn-aut-sei=木村
kn-aut-mei=正司
aut-affil-num=6
ORCID=

en-aut-name=TakedaKou
en-aut-sei=Takeda
en-aut-mei=Kou
kn-aut-name=武田光
kn-aut-sei=武田
kn-aut-mei=光
aut-affil-num=7
ORCID=

en-aut-name=FujiiAkinobu
en-aut-sei=Fujii
en-aut-mei=Akinobu
kn-aut-name=藤井章伸
kn-aut-sei=藤井
kn-aut-mei=章伸
aut-affil-num=8
ORCID=

en-aut-name=NagahanaHaruki
en-aut-sei=Nagahana
en-aut-mei=Haruki
kn-aut-name=長花晴樹
kn-aut-sei=長花
kn-aut-mei=晴樹
aut-affil-num=9
ORCID=

en-aut-name=HaraokaShoichi
en-aut-sei=Haraoka
en-aut-mei=Shoichi
kn-aut-name=原岡昭一
kn-aut-sei=原岡
kn-aut-mei=昭一
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=7
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=8
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=9
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=10
en-affil=
kn-affil=岡山大学医学部附属病院中央検査部
en-keyword=クモ膜下出血
kn-keyword=クモ膜下出血
en-keyword=術後心電図
kn-keyword=術後心電図
en-keyword=脳外科手術
kn-keyword=脳外科手術
en-keyword=脳性T波
kn-keyword=脳性T波
en-keyword=カテコールアミン
kn-keyword=カテコールアミン
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=5-6
article-no=
start-page=579
end-page=592
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Body surface isopotential maps in the case of R.B.B.B. special reference to Atrial Septal Defect. (Comparative study of the data from cardiac catetherization and two dimensional echocardiograms.)
kn-title=右脚ブロックの体表面心臓電位図（特に心房中隔欠損症を中心として）―超音波検査,右心カテーテル検査との対比―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A body surface isopotential map was recorded in 30 cases of ASD and 3 cases of ECD with right bundle branch block in ECG, then analyzed in comparison with results obtained by cardiac catetherization and two dimensional echocardiograms. 1) In all cases of right bundle branch block, breakthrough minimum appeared later and shifted to the left compared with the normal. 2) Breakthrough minimum of ASD and ECD appeared progressively later associated with Qp/Qs ratio and left to right intracardiac shunt ratio obtained with cardiac catetherization and RVDd with echocardiogram. Breakthrough minimum of ASD and ECD moved to the left accompanied by increases in mean RV pressure, mean PA pressure and RVDd. 3) R'max voltage, the maximum positive potential in the late stage of ventricular depolarization on the right precordial area, increased and correlated well with the mean RV pressure and left to right shunt ratio increment. 4) In the case of ASD, breakthrough minimum appeared later and shifted to the left along with age.
en-copyright=
kn-copyright=

en-aut-name=YoshidaHidenori
en-aut-sei=Yoshida
en-aut-mei=Hidenori
kn-aut-name=吉田英紀
kn-aut-sei=吉田
kn-aut-mei=英紀
aut-affil-num=1
ORCID=

en-aut-name=IhoriyaKazuo
en-aut-sei=Ihoriya
en-aut-mei=Kazuo
kn-aut-name=庵谷和夫
kn-aut-sei=庵谷
kn-aut-mei=和夫
aut-affil-num=2
ORCID=

en-aut-name=NagahanaHaruki
en-aut-sei=Nagahana
en-aut-mei=Haruki
kn-aut-name=長花晴樹
kn-aut-sei=長花
kn-aut-mei=晴樹
aut-affil-num=3
ORCID=

en-aut-name=NishiharaMasanobu
en-aut-sei=Nishihara
en-aut-mei=Masanobu
kn-aut-name=西原正信
kn-aut-sei=西原
kn-aut-mei=正信
aut-affil-num=4
ORCID=

en-aut-name=HyodoTatsuo
en-aut-sei=Hyodo
en-aut-mei=Tatsuo
kn-aut-name=兵頭多津男
kn-aut-sei=兵頭
kn-aut-mei=多津男
aut-affil-num=5
ORCID=

en-aut-name=UchidaToshiaki
en-aut-sei=Uchida
en-aut-mei=Toshiaki
kn-aut-name=内田俊明
kn-aut-sei=内田
kn-aut-mei=俊明
aut-affil-num=6
ORCID=

en-aut-name=KimuraMasashi
en-aut-sei=Kimura
en-aut-mei=Masashi
kn-aut-name=木村正司
kn-aut-sei=木村
kn-aut-mei=正司
aut-affil-num=7
ORCID=

en-aut-name=TakedaKou
en-aut-sei=Takeda
en-aut-mei=Kou
kn-aut-name=武田光
kn-aut-sei=武田
kn-aut-mei=光
aut-affil-num=8
ORCID=

en-aut-name=FujiiAkinobu
en-aut-sei=Fujii
en-aut-mei=Akinobu
kn-aut-name=藤井章伸
kn-aut-sei=藤井
kn-aut-mei=章伸
aut-affil-num=9
ORCID=

en-aut-name=SaitoDaiji
en-aut-sei=Saito
en-aut-mei=Daiji
kn-aut-name=斉藤大治
kn-aut-sei=斉藤
kn-aut-mei=大治
aut-affil-num=10
ORCID=

en-aut-name=TanataniSetsuro
en-aut-sei=Tanatani
en-aut-mei=Setsuro
kn-aut-name=種谷節郎
kn-aut-sei=種谷
kn-aut-mei=節郎
aut-affil-num=11
ORCID=

en-aut-name=KitaToshimasa
en-aut-sei=Kita
en-aut-mei=Toshimasa
kn-aut-name=喜多利正
kn-aut-sei=喜多
kn-aut-mei=利正
aut-affil-num=12
ORCID=

en-aut-name=SakaiHiroshi
en-aut-sei=Sakai
en-aut-mei=Hiroshi
kn-aut-name=堺裕
kn-aut-sei=堺
kn-aut-mei=裕
aut-affil-num=13
ORCID=

en-aut-name=HaraokaShoichi
en-aut-sei=Haraoka
en-aut-mei=Shoichi
kn-aut-name=原岡昭一
kn-aut-sei=原岡
kn-aut-mei=昭一
aut-affil-num=14
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=7
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=8
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=9
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=10
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=11
en-affil=
kn-affil=榊原十全病院

affil-num=12
en-affil=
kn-affil=榊原十全病院

affil-num=13
en-affil=
kn-affil=榊原十全病院

affil-num=14
en-affil=
kn-affil=岡山大学医学部附属病院中央検査部
en-keyword=体表面心臓電位図
kn-keyword=体表面心臓電位図
en-keyword=右脚ブロック
kn-keyword=右脚ブロック
en-keyword=心房中隔欠損
kn-keyword=心房中隔欠損
en-keyword=Breakthrough
kn-keyword=Breakthrough
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=5-6
article-no=
start-page=555
end-page=577
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A cardiovascular epidemiologic survey in three different areas in Okayama prefecture (Sakuto-cho, Sanyo-cho and Osafune-cho) in 1980. V. Special reference to HDL-cholesterol and total cholesterol.
kn-title=岡山県の三地区(作東町,山陽町,長船町)の循環器疫学調査 第5報 昭和55年度の血清コレステロール,HDLコレステロールとの関係について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A cardiovascular epidemiologic study was performed in three different areas in Okayama prefecture in 1980. The relationship between serum total and HDL-cholesterol and blood pressure, ECG findings, clinical disorders, obesity, drinking and smoking was examined in a total of 1092 subjects, with an age-range 49-79 years. The following results were obtained: 1) Along with an elevation of blood pressure, Code 1-0 in the ECG decreased and the code for left ventricular hypertrophy (a combination of two or more subcategories of Code 3 or of Code 3 with Code 4 or 5) increased. Code 4+5 increased in parallel with the systolic blood pressure and Code 5 increased directly with the diastolic blood pressure. 2) In the group of essential hypertension and coronary arterial disorders, HDL cholesterol/total cholesterol ratios were significantly low, and total cholesterol and the Atherogenic Index were in high compared with the normal group. 3) Along with an increase in body weight, the HDL-cholesterol/total cholesterol ratio decreased, while total cholesterol and the Atherogenic Index increased significantly. 4) The group with a drinking habit showed high HDL-cholesterol values but HDLcholesterol showed lower values in the group with a smoking habit.
en-copyright=
kn-copyright=

en-aut-name=HaraokaShoichi
en-aut-sei=Haraoka
en-aut-mei=Shoichi
kn-aut-name=原岡昭一
kn-aut-sei=原岡
kn-aut-mei=昭一
aut-affil-num=1
ORCID=

en-aut-name=YoshidaHidenori
en-aut-sei=Yoshida
en-aut-mei=Hidenori
kn-aut-name=吉田英紀
kn-aut-sei=吉田
kn-aut-mei=英紀
aut-affil-num=2
ORCID=

en-aut-name=SaitoDaiji
en-aut-sei=Saito
en-aut-mei=Daiji
kn-aut-name=斉藤大治
kn-aut-sei=斉藤
kn-aut-mei=大治
aut-affil-num=3
ORCID=

en-aut-name=UedaMinoru
en-aut-sei=Ueda
en-aut-mei=Minoru
kn-aut-name=上田稔
kn-aut-sei=上田
kn-aut-mei=稔
aut-affil-num=4
ORCID=

en-aut-name=KusachiShozo
en-aut-sei=Kusachi
en-aut-mei=Shozo
kn-aut-name=草地省蔵
kn-aut-sei=草地
kn-aut-mei=省蔵
aut-affil-num=5
ORCID=

en-aut-name=NishiyamaOsamu
en-aut-sei=Nishiyama
en-aut-mei=Osamu
kn-aut-name=西山修
kn-aut-sei=西山
kn-aut-mei=修
aut-affil-num=6
ORCID=

en-aut-name=YasuharaKoichiro
en-aut-sei=Yasuhara
en-aut-mei=Koichiro
kn-aut-name=安原耕一郎
kn-aut-sei=安原
kn-aut-mei=耕一郎
aut-affil-num=7
ORCID=

en-aut-name=YamadaNobuyuki
en-aut-sei=Yamada
en-aut-mei=Nobuyuki
kn-aut-name=山田信行
kn-aut-sei=山田
kn-aut-mei=信行
aut-affil-num=8
ORCID=

en-aut-name=IhoriyaKazuo
en-aut-sei=Ihoriya
en-aut-mei=Kazuo
kn-aut-name=庵谷和夫
kn-aut-sei=庵谷
kn-aut-mei=和夫
aut-affil-num=9
ORCID=

en-aut-name=FujiiAkinobu
en-aut-sei=Fujii
en-aut-mei=Akinobu
kn-aut-name=藤井章信
kn-aut-sei=藤井
kn-aut-mei=章信
aut-affil-num=10
ORCID=

en-aut-name=KimuraShoji
en-aut-sei=Kimura
en-aut-mei=Shoji
kn-aut-name=木村正司
kn-aut-sei=木村
kn-aut-mei=正司
aut-affil-num=11
ORCID=

en-aut-name=TakedaKo
en-aut-sei=Takeda
en-aut-mei=Ko
kn-aut-name=武田光
kn-aut-sei=武田
kn-aut-mei=光
aut-affil-num=12
ORCID=

en-aut-name=HyodoTatsuo
en-aut-sei=Hyodo
en-aut-mei=Tatsuo
kn-aut-name=兵頭多津男
kn-aut-sei=兵頭
kn-aut-mei=多津男
aut-affil-num=13
ORCID=

en-aut-name=UchidaToshiaki
en-aut-sei=Uchida
en-aut-mei=Toshiaki
kn-aut-name=内田俊明
kn-aut-sei=内田
kn-aut-mei=俊明
aut-affil-num=14
ORCID=

en-aut-name=NishiharaMasanobu
en-aut-sei=Nishihara
en-aut-mei=Masanobu
kn-aut-name=西原正信
kn-aut-sei=西原
kn-aut-mei=正信
aut-affil-num=15
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=吉田暎
kn-aut-sei=吉田
kn-aut-mei=暎
aut-affil-num=16
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=日下幸恵
kn-aut-sei=日下
kn-aut-mei=幸恵
aut-affil-num=17
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=7
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=8
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=9
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=10
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=11
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=12
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=13
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=14
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=15
en-affil=
kn-affil=岡山大学医学部第一内科学教室

affil-num=16
en-affil=
kn-affil=岡山県環境保健部

affil-num=17
en-affil=
kn-affil=岡山県環境保健部
en-keyword=HDLコレステロール
kn-keyword=HDLコレステロール
en-keyword=血清総コレステロール
kn-keyword=血清総コレステロール
en-keyword=Atherogenic Index
kn-keyword=Atherogenic Index
en-keyword=循環器疫学調査
kn-keyword=循環器疫学調査
END

start-ver=1.4
cd-journal=joma
no-vol=96
cd-vols=
no-issue=9-10
article-no=
start-page=921
end-page=932
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1984
dt-pub=19841030
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Echocardiographic and body surface mapping investigation of cardiac hypertrophy in cardiomyopathy and hypertension.
kn-title=高血圧心と肥大型心筋症に関する心エコー図および体表面電位図による検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=It is often difficult to diagnose between cardiomegaly due to essential hypertension (EH) and that due to idiopathic cardiomyopathy (ICM). For the purpose of finding some useful clinical data for differentiating between cardiomegaly due to EH and that due to ICM, we examined the E.C.G., chest X-P and U.C.G. findings of 66 cases of EH and 46 cases of ICM. Body surface isopotential mappings (maps) were studied in 16 cases of EH and 18 cases of hypertrophic cardiomyopathy (HCM). Among those showing ASH or SH patterns in U.C.G., the ages of the EH group were greater than those of the ICM group. The thickness of the intraventricular septum (IVST) and the IVST/PWT ratio were greater and the left ventricular diastolic dimenaion (LVDd) was smaller in the ICM group than in the EH group. Among EH patients, the age and the systolic blood pressure were greater in those with abnormal U.C.G. findings. The septal activation time (SAT) obtained from maps correlated well with the IVST (r=0.55, p<0.005) and IVST/PWT ratio (r=0.61, p<0.005) obtained from U.C.G. In all of the HCM cases, the values os SAT were over 30msec., the values of IVST over 25mm and the IVST/PWT ratio over 2.0. These results suggest that these parameters should discriminate cardiomegaly due to EH from that due to ICM.
en-copyright=
kn-copyright=

en-aut-name=YoshidaHidenori
en-aut-sei=Yoshida
en-aut-mei=Hidenori
kn-aut-name=吉田英紀
kn-aut-sei=吉田
kn-aut-mei=英紀
aut-affil-num=1
ORCID=

en-aut-name=HaraokaShoichi
en-aut-sei=Haraoka
en-aut-mei=Shoichi
kn-aut-name=原岡昭一
kn-aut-sei=原岡
kn-aut-mei=昭一
aut-affil-num=2
ORCID=

en-aut-name=IhoriyaKazuo
en-aut-sei=Ihoriya
en-aut-mei=Kazuo
kn-aut-name=庵谷和夫
kn-aut-sei=庵谷
kn-aut-mei=和夫
aut-affil-num=3
ORCID=

en-aut-name=NagahanaHaruki
en-aut-sei=Nagahana
en-aut-mei=Haruki
kn-aut-name=長花晴樹
kn-aut-sei=長花
kn-aut-mei=晴樹
aut-affil-num=4
ORCID=

en-aut-name=NishiharaMasanobu
en-aut-sei=Nishihara
en-aut-mei=Masanobu
kn-aut-name=西原正信
kn-aut-sei=西原
kn-aut-mei=正信
aut-affil-num=5
ORCID=

en-aut-name=KimuraMasashi
en-aut-sei=Kimura
en-aut-mei=Masashi
kn-aut-name=木村正司
kn-aut-sei=木村
kn-aut-mei=正司
aut-affil-num=6
ORCID=

en-aut-name=ImatakiKensuke
en-aut-sei=Imataki
en-aut-mei=Kensuke
kn-aut-name=今滝健介
kn-aut-sei=今滝
kn-aut-mei=健介
aut-affil-num=7
ORCID=

en-aut-name=IhoriyaFumio
en-aut-sei=Ihoriya
en-aut-mei=Fumio
kn-aut-name=庵谷文夫
kn-aut-sei=庵谷
kn-aut-mei=文夫
aut-affil-num=8
ORCID=

en-aut-name=MorichikaYutaka
en-aut-sei=Morichika
en-aut-mei=Yutaka
kn-aut-name=森近豊
kn-aut-sei=森近
kn-aut-mei=豊
aut-affil-num=9
ORCID=

en-aut-name=OnishiShigeaki
en-aut-sei=Onishi
en-aut-mei=Shigeaki
kn-aut-name=大西茂明
kn-aut-sei=大西
kn-aut-mei=茂明
aut-affil-num=10
ORCID=

en-aut-name=FujiiAkinobu
en-aut-sei=Fujii
en-aut-mei=Akinobu
kn-aut-name=藤井章伸
kn-aut-sei=藤井
kn-aut-mei=章伸
aut-affil-num=11
ORCID=

en-aut-name=SaitoDaiji
en-aut-sei=Saito
en-aut-mei=Daiji
kn-aut-name=斉藤大治
kn-aut-sei=斉藤
kn-aut-mei=大治
aut-affil-num=12
ORCID=

en-aut-name=NagashimaHideo
en-aut-sei=Nagashima
en-aut-mei=Hideo
kn-aut-name=長島秀夫
kn-aut-sei=長島
kn-aut-mei=秀夫
aut-affil-num=13
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院中央検査部

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院中央検査部

affil-num=3
en-affil=
kn-affil=岡山大学医学部第一内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部第一内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部第一内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部第一内科

affil-num=7
en-affil=
kn-affil=岡山大学医学部第一内科

affil-num=8
en-affil=
kn-affil=岡山大学医学部第一内科

affil-num=9
en-affil=
kn-affil=岡山大学医学部第一内科

affil-num=10
en-affil=
kn-affil=岡山大学医学部第一内科

affil-num=11
en-affil=
kn-affil=岡山大学医学部第一内科

affil-num=12
en-affil=
kn-affil=岡山大学医学部第一内科

affil-num=13
en-affil=
kn-affil=岡山大学医学部第一内科
en-keyword=体表面電位図
kn-keyword=体表面電位図
en-keyword=肥大型心筋症
kn-keyword=肥大型心筋症
en-keyword=比対称性中隔肥大
kn-keyword=比対称性中隔肥大
END

start-ver=1.4
cd-journal=joma
no-vol=96
cd-vols=
no-issue=5-6
article-no=
start-page=537
end-page=551
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1984
dt-pub=19840430
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Embryologic, histochemical and electron microscopic study of rat hippocampal formation
kn-title=海馬領域の発生学的・組織化学的・電子顕微鏡的研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=An embryologic study of rat hippocampal formation was performed. By the silver sulfide method for light microscopy, the same positive reaction as in adult rats was observed in 20-day rats in the same regions: the border between stratum radiatum and stratum pyramidale of h(3) and h(4), hilus fascia dentata(h5) and stratum multiforme of Gyrus dentatus. These regions corresponded to the site of mossy fiber endings. In the silver sulfide method modified for electron microscopy, deposits of silver grains were observed in mossy fiber endings of 8-day rats, and the morphology of mossy fiber endings of 14-day rats was similar to that of adult rats. These results suggest that these areas begin to mature in 8 days and complete maturation in 20 days after birth.
en-copyright=
kn-copyright=

en-aut-name=FujiiRyuhei
en-aut-sei=Fujii
en-aut-mei=Ryuhei
kn-aut-name=藤井龍平
kn-aut-sei=藤井
kn-aut-mei=龍平
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一解剖学教室
en-keyword=海馬領域
kn-keyword=海馬領域
en-keyword=発生
kn-keyword=発生
en-keyword=組織化学
kn-keyword=組織化学
en-keyword=電子顕微鏡
kn-keyword=電子顕微鏡
END

start-ver=1.4
cd-journal=joma
no-vol=96
cd-vols=
no-issue=5-6
article-no=
start-page=473
end-page=488
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1984
dt-pub=19840430
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Exercise vectorcardiographic study in essential hypertension
kn-title=本態性高血圧症患者の運動負荷ベクトル心電図
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Tha cause of ST-T changes with QRS high voltage in essential hypertension was investigated using Frank lead vectorcardiograms. Submaximal treadmill exercise was performed according to the modified Bruce protocol. The patients were divided into three groups. Group N consisted of 29 normal subjects; Group I (ischemic heart disease) consisted of 10 patients with angina pectoris and 16 patients with angiographically documented narrowing of one or more coronary arteries and Group H (essential hypertension) was subdivided into four groups according to ECG findings: Group H-1 of 30 subjects with normal ECG, Group H-2 of 20 subjects with QRS high voltage (Sv(1)+Rv(6)≧35mm) with normal ST-T pattern, Group H-3 of 20 subjects with QRS high voltage with ST-T changes but no "strain pattern" and Group 4 of 20 subjects with QRS high voltage and "strain pattern". After exercise, the maximum spatial QRS vectors shifted posteriorly and to the left in all groups. In Group N, the maximum spatial T vector was reduced in magnitude, and directed anteriorly, superiorly and to the left after exercise. The T loop configuration showed no significant changes, though slightly rounded and inscribed uniformly. In Group I, the maximum spatial T vector decreased in magnitude as in Group N, but was directed in significantly more ways than in Group N. In a few cases, the vectors were extremely dislocated upward. The T loop configurations had wide variation. This variation of the T loop after exercise was characteristic of Group I. In group H, the maximum spatial T vector was also reduced in size, while the azimuth, elevation and spatial QRS-T angle moved in the opposite direction of Group N, as cardiac hypertrophy beveloped. Analysis of T loop configuration changes induced by exercise strongly suggested that the ST-T changes in Group H-3 were related to primary changes due to myocardial ishemia. Effects of exercise on spatial T vectors and T loop configurations in Group H-4 were quite different from those in Group I, so that the ST-T changes in this group seemed to be secondary changes in association with QRS high voltage.
en-copyright=
kn-copyright=

en-aut-name=FujiiAkinobu
en-aut-sei=Fujii
en-aut-mei=Akinobu
kn-aut-name=藤井章伸
kn-aut-sei=藤井
kn-aut-mei=章伸
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一内科学教室
en-keyword=本能性高血圧症
kn-keyword=本能性高血圧症
en-keyword=運動負荷 (treadmill test)
kn-keyword=運動負荷 (treadmill test)
en-keyword=ベクトル心電図 (Frank法)
kn-keyword=ベクトル心電図 (Frank法)
END

start-ver=1.4
cd-journal=joma
no-vol=95
cd-vols=
no-issue=5-6
article-no=
start-page=497
end-page=506
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1983
dt-pub=19830630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A cardiovascular epidemiologic survey of three areas of Okayama prefecture with regard to differences in HDL-and total- cholesterol according to age and sex.
kn-title=岡山県の三地区(作東町,山陽町,長船町)の循環器疫学調査 第6報,昭和56年度の年齢,性別,内科診断別,HDL-コレステロール値の検討.
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A cardiovascular epidemiologic survey was performed in three areas (Sakuto-cho, Sanyo-cho and Osafune-cho) of Okayama prefecture in 1981 to determine age and sex differences in serum HDL-and total-cholesterol. A total of 1077 subjects, 389 male and 688 female, with 412 under 60 years of age (younger group) and 655 over 60 years of age (elder group) were studied, and the following results were obtained. The ratio of HDL-cholesterol to total-cholesterol in subjects from the mountain town of Sakutocho was higher than in those from urban areas (Sanyo-cho and Osafune-cho). In the female group, HDL-and total-cholesterol values were higher and the HDL-/total-cholesterol ratio lower than in the male group. Among healthy individuals, the value of HDL-cholesterol was higher in the younger and female groups. However, in the female group, the total-cholesterol value was also high, so there was no significant difference between sex concerning the HDL-cholesterol to total-cholesterol ratio. In those with hypertension, ECG abnormalities and obesity, we found a higher total cholesterol level and lower HDL-cholesterol to total-cholesterol ratio than in the healthy subjects. This tendency was especially remarkable in the elder group. We found no differences in the HDL cholesterol values according to sex and age. However there was lower HDL-cholesterol to total-cholesterol ratio in the female group than in the male group resulting from a higher total-cholesterol value in the former.
en-copyright=
kn-copyright=

en-aut-name=HaraokaShoichi
en-aut-sei=Haraoka
en-aut-mei=Shoichi
kn-aut-name=原岡昭一
kn-aut-sei=原岡
kn-aut-mei=昭一
aut-affil-num=1
ORCID=

en-aut-name=YoshidaHidenori
en-aut-sei=Yoshida
en-aut-mei=Hidenori
kn-aut-name=吉田英紀
kn-aut-sei=吉田
kn-aut-mei=英紀
aut-affil-num=2
ORCID=

en-aut-name=SaitoDaiji
en-aut-sei=Saito
en-aut-mei=Daiji
kn-aut-name=斉藤大治
kn-aut-sei=斉藤
kn-aut-mei=大治
aut-affil-num=3
ORCID=

en-aut-name=YamadaNobuyuki
en-aut-sei=Yamada
en-aut-mei=Nobuyuki
kn-aut-name=山田信行
kn-aut-sei=山田
kn-aut-mei=信行
aut-affil-num=4
ORCID=

en-aut-name=IhoriyaKazuo
en-aut-sei=Ihoriya
en-aut-mei=Kazuo
kn-aut-name=庵谷和夫
kn-aut-sei=庵谷
kn-aut-mei=和夫
aut-affil-num=5
ORCID=

en-aut-name=FujiiAkinobu
en-aut-sei=Fujii
en-aut-mei=Akinobu
kn-aut-name=藤井章伸
kn-aut-sei=藤井
kn-aut-mei=章伸
aut-affil-num=6
ORCID=

en-aut-name=UchidaToshiaki
en-aut-sei=Uchida
en-aut-mei=Toshiaki
kn-aut-name=内田俊明
kn-aut-sei=内田
kn-aut-mei=俊明
aut-affil-num=7
ORCID=

en-aut-name=KimuraMasashi
en-aut-sei=Kimura
en-aut-mei=Masashi
kn-aut-name=木村正司
kn-aut-sei=木村
kn-aut-mei=正司
aut-affil-num=8
ORCID=

en-aut-name=TakedaKo
en-aut-sei=Takeda
en-aut-mei=Ko
kn-aut-name=武田光
kn-aut-sei=武田
kn-aut-mei=光
aut-affil-num=9
ORCID=

en-aut-name=NishiharaMasanobu
en-aut-sei=Nishihara
en-aut-mei=Masanobu
kn-aut-name=西原正信
kn-aut-sei=西原
kn-aut-mei=正信
aut-affil-num=10
ORCID=

en-aut-name=HyodoTatsuo
en-aut-sei=Hyodo
en-aut-mei=Tatsuo
kn-aut-name=兵頭多津男
kn-aut-sei=兵頭
kn-aut-mei=多津男
aut-affil-num=11
ORCID=

en-aut-name=AbeYukihiro
en-aut-sei=Abe
en-aut-mei=Yukihiro
kn-aut-name=安部行弘
kn-aut-sei=安部
kn-aut-mei=行弘
aut-affil-num=12
ORCID=

en-aut-name=OhnishiShigeaki
en-aut-sei=Ohnishi
en-aut-mei=Shigeaki
kn-aut-name=大西茂明
kn-aut-sei=大西
kn-aut-mei=茂明
aut-affil-num=13
ORCID=

en-aut-name=MinatoTakeshi
en-aut-sei=Minato
en-aut-mei=Takeshi
kn-aut-name=湊武
kn-aut-sei=湊
kn-aut-mei=武
aut-affil-num=14
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学第一内科

affil-num=2
en-affil=
kn-affil=岡山大学第一内科

affil-num=3
en-affil=
kn-affil=岡山大学第一内科

affil-num=4
en-affil=
kn-affil=岡山大学第一内科

affil-num=5
en-affil=
kn-affil=岡山大学第一内科

affil-num=6
en-affil=
kn-affil=岡山大学第一内科

affil-num=7
en-affil=
kn-affil=岡山大学第一内科

affil-num=8
en-affil=
kn-affil=岡山大学第一内科

affil-num=9
en-affil=
kn-affil=岡山大学第一内科

affil-num=10
en-affil=
kn-affil=岡山大学第一内科

affil-num=11
en-affil=
kn-affil=岡山大学第一内科

affil-num=12
en-affil=
kn-affil=岡山大学第一内科

affil-num=13
en-affil=
kn-affil=岡山大学第一内科

affil-num=14
en-affil=
kn-affil=岡山大学第一内科
en-keyword=循環器疫学調査
kn-keyword=循環器疫学調査
en-keyword=HDL-コレステロール
kn-keyword=HDL-コレステロール
en-keyword=高血圧
kn-keyword=高血圧
en-keyword=虚血性心疾患
kn-keyword=虚血性心疾患
en-keyword=Atherogenic Index
kn-keyword=Atherogenic Index
END