start-ver=1.4
cd-journal=joma
no-vol=15
cd-vols=
no-issue=
article-no=
start-page=59
end-page=73
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2025
dt-pub=20250328
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effects of Career Years on the Coordination Behavior of Yogo Teachers
kn-title=養護教諭のコーディネーション行動に及ぼすキャリア年数の影響
en-subtitle=
kn-subtitle=
en-abstract=The purpose of this study was to clarify the factors influencing coordination behavior of Yogo teachers and the relationship between the occurrence process of the factors and career years. The subjects analyzed were 695 persons working in public elementary and junior high schools. The effect of years of career was seen in the improvement of scale scores of factors related to the stages of coordination behavior and motivation, as well as subscale scores of the factors. <br>
The relationship between the number of years of career and factors related to the generation process of coordination behavior suggested three characteristics. That is, (1) The establishment of a foundation for organizational support that starts from collaboration, due to the correlation between factors showing high subscale scores unaffected by the number of years of career, and (2) The correlation among factors of motivational factors whose subscale scores increase with the number of years of career, which leads to the promotion of individualized support efforts, and (3) Correlation between factors of leader recognition and individual support seen in the career category of 11 years or more, and which leads to the promotion of expansion to management of organizational support.
kn-abstract=　本研究の目的は，養護教諭のコーディネーション行動に影響する要因やその因子の傾向をキャリア年数から捉え，これらとコーディネーション行動の生起プロセスとの関係について明らかにすることであった。分析対象は，公立小学校・中学校勤務695名とした。キャリア年数の影響は，コーディネーション行動と動機づけの段階に関わる要因の尺度得点や，因子の下位尺度得点の向上に見られた。また，キャリア年数とコーディネーション行動の生起プロセスに関わる因子間の関係からは，（1）キャリア年数に影響されない高い下位尺度得点を示す因子間相関による，協働を起点にした組織支援の基盤づくり，（2）キャリア年数により下位尺度得点が高まる動機づけ要因の因子間相関による，個別支援の取組推進へのつながり，（3）11年以上キャリア区分で見られるリーダー認知と個別支援の因子間相関，及び組織的支援のマネジメントへの広がり，の３つの特徴をもつことが示唆された。
en-copyright=
kn-copyright=

en-aut-name=SUZUKIKaoru
en-aut-sei=SUZUKI
en-aut-mei=Kaoru
kn-aut-name=鈴木薫
kn-aut-sei=鈴木
kn-aut-mei=薫
aut-affil-num=1
ORCID=

en-aut-name=MIMURAYukari
en-aut-sei=MIMURA
en-aut-mei=Yukari
kn-aut-name=三村由香里
kn-aut-sei=三村
kn-aut-mei=由香里
aut-affil-num=2
ORCID=

affil-num=1
en-affil=Research student, United Graduate School of Education, Hyogo University of Teacher Education
kn-affil=兵庫教育大学連合大学院教育学研究科研究生

affil-num=2
en-affil=Graduate School of Education, Okayama University
kn-affil=岡山大学学術研究院教育学域
en-keyword=養護教諭 (Yogo teacher)
kn-keyword=養護教諭 (Yogo teacher)
en-keyword=コーディネーション行動 (coordination behavior)
kn-keyword=コーディネーション行動 (coordination behavior)
en-keyword=尺度得点 (scale score)
kn-keyword=尺度得点 (scale score)
en-keyword=下位尺度得点 (subscale scoreｒ)
kn-keyword=下位尺度得点 (subscale scoreｒ)
en-keyword=行動の生起プロセス (process of behavioral development)
kn-keyword=行動の生起プロセス (process of behavioral development)
END

start-ver=1.4
cd-journal=joma
no-vol=14
cd-vols=
no-issue=
article-no=
start-page=17
end-page=31
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=20240329
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Interrelationship between Autonomous and Organizational Learning among Elementary School Teachers: Differences Arising from the Images of Organizational Learning
kn-title=小学校教師の自律的な学びを支える組織的な学び ―組織的な学びのイメージに基づく比較―
en-subtitle=
kn-subtitle=
en-abstract=　This study examined the interrelationship between autonomous and organizational learning among elementary school teachers. A questionnaire survey administered to Japanese public elementary school teachers received 99 responses. We measured four aspects of autonomous learning attitudes: “self-reflection,” “incorporating colleagues’ experiences,” “considering children’ s and parents’ perspectives,” and “challenging attitude.” Additionally, two facets of perceptions of professional learning community (PLC) were assessed: “shared mission and responsibility” and “collaborative reflection with colleagues,” serving as indicators of organizational learning. Positive and negative images of organizational learning were also examined. Correlation analysis revealed that the PLC perceptions of “shared mission and responsibility” and “collaborative reflection with colleagues” were positively associated with learning attitudes of “incorporating colleagues’ experiences.” Furthermore, a positive association was identified between the PLC perception of “collaborative reflection with colleagues” and the autonomous learning attitudes of “self-reflection.” However, it was observed that when teachers held a negative image of organizational learning, the interrelation between autonomous and organizational learning might be constrained or even exhibit a negative correlation.
kn-abstract=　本研究では，教師の自律的な学びと組織的な学びの連動を検討した。質問紙調査を実施し，公立小学校教師99名から回答を得た。既往知見を参考に，自律的な学習姿勢は4側面（「自己省察」，「同僚の経験の取り入れ」，「児童・保護者の視点の考慮」，「前向きな挑戦姿勢」），組織的な学びについては専門的な学習共同体（PLC）の認識の2要素（「使命と責任の共有」，「同僚との協働的省察」），組織的な学びに対するポジティブおよびネガティブなイメージを測定した。相関分析の結果，PLC 認識の「使命と責任の共有」と「同僚との協働的省察」は学習姿勢の「同僚の経験の取り入れ」と正の関連を示した。また，「同僚との協働的省察」は学習姿勢の「自己省察」とも正の関連を示した。しかし，組織的な学びにネガティブなイメージを抱く場合，自律的な学びと組織的な学びの連動は制限されたり，負の関係になる可能性が示唆された。
en-copyright=
kn-copyright=

en-aut-name=MISAWARyo
en-aut-sei=MISAWA
en-aut-mei=Ryo
kn-aut-name=三沢良
kn-aut-sei=三沢
kn-aut-mei=良
aut-affil-num=1
ORCID=

en-aut-name=MATSUEMomoka
en-aut-sei=MATSUE
en-aut-mei=Momoka
kn-aut-name=松江桃果
kn-aut-sei=松江
kn-aut-mei=桃果
aut-affil-num=2
ORCID=

affil-num=1
en-affil=Faculty of Education, Okayama University
kn-affil=岡山大学学術研究院教育学域

affil-num=2
en-affil=Akashi Municipal Futami-Nishi Junior School
kn-affil=明石市立二見西小学校
en-keyword=小学校教師 (elementary school teacher)
kn-keyword=小学校教師 (elementary school teacher)
en-keyword=自律的な学び (autonomous learning)
kn-keyword=自律的な学び (autonomous learning)
en-keyword=組織的な学び (organizational learning)
kn-keyword=組織的な学び (organizational learning)
en-keyword=専門職の学習共同体 (professional lea rning community)
kn-keyword=専門職の学習共同体 (professional lea rning community)
END

start-ver=1.4
cd-journal=joma
no-vol=14
cd-vols=
no-issue=
article-no=
start-page=1
end-page=15
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=20240329
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A Preliminary Study of School-Based Strengths Intervention with Japanese elementary school students: Through Classroom Activity to Promote Awareness of Strengths
kn-title=児童を対象とした強み介入の予備的検討 ―強みへの気付きを促す学級活動の授業を通して―
en-subtitle=
kn-subtitle=
en-abstract=This study aimed to assess the effectiveness of a preliminary strengths intervention lesson for children. The participants included 95 sixth-grade students, comprising 50 boys, 40 girls, and 5 of unknown gender. The findings revealed three key points. Firstly, life satisfaction and the sense of trust and acceptance significantly improved in post-event scores. Secondly, a noteworthy positive partial correlation was identified between the amount of change in attention to one's strengths and the amount of change in feelings of trust and acceptance. Additionally, a quantitative text analysis was conducted to explore the learning impressions of children whose focus on strengths improved versus those whose attention did not improve. Results indicated no significant bias in descriptions for each group. Overall, most of the children described subjective experiences of positive emotions. Lastly, the study discussed the lessons for intervention and research design as areas to address, providing insights into future perspectives.
kn-abstract=　本研究の目的は，児童を対象とした強み介入の予備的検討のために実践した強みへの気付きを促す授業の効果について検討することである。対象者は小学６年生95名(男子50名，女子40名，不明５名)であった。本研究によって以下の３点が明らかになった。まず，生活充実感と被信頼感・受容感の事後の得点が有意に向上した。次に，自己の強みへの注目の変化量と被信頼感・受容感の変化量で有意な正の偏相関が確認された。さらに，強みへの注目が向上した児童と向上しなかった児童の学習の感想を計量テキスト分析で検証した。その結果，群ごとに有意な記述の偏りは確認されなかった。全体として，児童の多くはポジティブな感情に関する主観的経験について記述していた。最後に，課題として介入で実施する授業と研究デザインを取り上げ，今後の展望について議論した。
en-copyright=
kn-copyright=

en-aut-name=IZUMITsuguyuki
en-aut-sei=IZUMI
en-aut-mei=Tsuguyuki
kn-aut-name=伊住継行
kn-aut-sei=伊住
kn-aut-mei=継行
aut-affil-num=1
ORCID=

en-aut-name=TODAAkane
en-aut-sei=TODA
en-aut-mei=Akane
kn-aut-name=戸田朱音
kn-aut-sei=戸田
kn-aut-mei=朱音
aut-affil-num=2
ORCID=

en-aut-name=OKURAHisashi
en-aut-sei=OKURA
en-aut-mei=Hisashi
kn-aut-name=大倉尚志
kn-aut-sei=大倉
kn-aut-mei=尚志
aut-affil-num=3
ORCID=

affil-num=1
en-affil=Faculty of Education, Okayama University
kn-affil=岡山大学学術研究院教育学域

affil-num=2
en-affil=Shintoku Elementary School
kn-affil=新得町立新得小学校

affil-num=3
en-affil=Hayashima Kindergarten
kn-affil=早島町立早島幼稚園
en-keyword=促進的援助 (facilitative assistance)
kn-keyword=促進的援助 (facilitative assistance)
en-keyword=強み介入 (strengths intervention)
kn-keyword=強み介入 (strengths intervention)
en-keyword=学級活動(２) (classroom activities (2))
kn-keyword=学級活動(２) (classroom activities (2))
en-keyword=児童 (children)
kn-keyword=児童 (children)
en-keyword=計量テキスト分析 (quantitative text analysis)
kn-keyword=計量テキスト分析 (quantitative text analysis)
END

start-ver=1.4
cd-journal=joma
no-vol=20
cd-vols=
no-issue=
article-no=
start-page=9
end-page=15
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=20221225
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=乳幼児の親に対する養育省察機能質問票を開発する試み
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=　幼児の親に対する「養育省察機能質問票」（PRFQ）18項目版の日本語版（PRFQJ）が開発された。原版がバック・トランスレーションを通して日本語に訳された。この日本語版に因子分析を行った結果，確信的省察，省察不全，省察的姿勢という３つの因子が抽出された。この３因子に負荷の高い項目から成る下位尺度のα係数は. 80以上であった。この過程で２つの項目がすべての因子に負荷が低いので削除された。この質問票の妥当性確認のために，自己および他者の内面への意識，育児自己効力感，アレキシサイミア傾向との関連を検討した。この質間票で査定される省察機能は育児自己効力感と関連していた。「省察的姿勢」は自己および他者の内面への意識と正の相関を示し，「省察不全」はアレキシサイミア傾向と正の相関を示した。しかし，さらに妥当性の検討を行う必要があると思われる。
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=上地雄一郎
kn-aut-sei=上地
kn-aut-mei=雄一郎
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=小川紗有美
kn-aut-sei=小川
kn-aut-mei=紗有美
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院社会文化科学研究科

affil-num=2
en-affil=
kn-affil=三宅医院
en-keyword=乳幼児の親
kn-keyword=乳幼児の親
en-keyword=養育省察機能質問票(PRFQ)
kn-keyword=養育省察機能質問票(PRFQ)
en-keyword=日本語版
kn-keyword=日本語版
en-keyword=信頼性
kn-keyword=信頼性
en-keyword=妥当性
kn-keyword=妥当性
END

start-ver=1.4
cd-journal=joma
no-vol=20
cd-vols=
no-issue=
article-no=
start-page=1
end-page=8
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=20221225
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=サザンプトン・マインドフルネス質問票日本語版(SMQJ)作成の試み
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=　本研究では，マインドフルネスを測定するために開発された「サザンプトン・マインドフルネス質問票Southampton Mindfulness Questionnaire：SMQ」の日本語版（SMQJ）を作成し，初段階の信頼性と妥当性の検討を行った。SMQJを構成する16項目のα係数はα=.73で，まずまずの信頼性が得られた。SMQJと日本語版MAASとの相関係数はr=.27と，有意ではあるが低く，これはMAASが測定する傾向とSMQJが測定するものとの相違による結果だと思われた。SMQJと，Galexで測定されるアレキシサイミアとの相関については，SMQJと「体感・感情の認識不全」がr=.30の有意な相関を示したが，「空想・省察の不全」とは無相関であった。また，SMQJの因子分析の結果，２因子が抽出されたが，この因子分析によってSMQJの項目の１つについて日本語訳を修正する必要性が示唆された。
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=上地雄一郎
kn-aut-sei=上地
kn-aut-mei=雄一郎
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院社会文化科学研究科
en-keyword=サザンプトン・マイドフルネス質問票
kn-keyword=サザンプトン・マイドフルネス質問票
en-keyword=日本語版
kn-keyword=日本語版
en-keyword=信頼性
kn-keyword=信頼性
en-keyword=妥当性
kn-keyword=妥当性
END

start-ver=1.4
cd-journal=joma
no-vol=16
cd-vols=
no-issue=
article-no=
start-page=27
end-page=35
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2018
dt-pub=20181225
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=メンタライゼーション査定面接改訂版（MAI-R）の作成
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=本研究では，メンタライジング能力を測定するために，対人葛藤場面についての「メンタライゼーション査定面接改訂版」 (Mentalization Assessment Interview-the Revised Version; MAI-R) を作成した。MAI-Rは高い内的整合性を有しており，２名の評定者の評定同士も高い相関を示した。また，MAI-Rの妥当性については，MAI-R総得点は，愛着回避とは低い負の相関を示した。そして，MCQ-30によって測定された「心配への注目」および「思考の制御」とは有意な正の相関を示した。共感との関連については，EESRで分類された共感の4タイプの間でMAI-Rの得点に有意差は認められなかった。つまり，MAI-Rは，高い内的整合性および評定者間信頼性を示したが，妥当性が充分に証明されたとは言えない。
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藩艶麗
kn-aut-sei=藩
kn-aut-mei=艶麗
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=上地雄一郎
kn-aut-sei=上地
kn-aut-mei=雄一郎
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=UCLA

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=メンタライジング能力
kn-keyword=メンタライジング能力
en-keyword=メンタライゼーション
kn-keyword=メンタライゼーション
en-keyword=対人葛藤
kn-keyword=対人葛藤
END

start-ver=1.4
cd-journal=joma
no-vol=14
cd-vols=
no-issue=
article-no=
start-page=37
end-page=46
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2016
dt-pub=20161225
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=メタ認知的自覚質問票の信頼性と妥当性の検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=本研究では，抑うつに焦点を合わせたメタ認知を測定するためのメタ認知的自覚質問票を作成した。主成分分析の結果，先行研究である， Teasdale et al. (1995) のMetacognitive Awareness Questionnaire (MAQ) 同様，単主成分が抽出され，単主成分構造が妥当であると判断された。Cronbachのα係数を算出したところa=.72であった。また，各尺度間における相関係数を算出した結果，Metacognitive Questionnaire (MCQ) における「心配の制御不能性と危機に関するネガティブな信念」「心配についてのポジティブな信念」，「認知的自信の低さ」及び「思考制御の必要性」との間に正の相関，FFMQにおける「Nonjudging」と「Nonreacting」との間に負の相関がみられた。以上のことから，メタ認知的自覚質問票におけるある一定の信頼性及び妥当性が確認された。
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=谷口純代
kn-aut-sei=谷口
kn-aut-mei=純代
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=上地雄一郎
kn-aut-sei=上地
kn-aut-mei=雄一郎
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=愛媛県南予子ども・女性支援センター

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=メタ認知
kn-keyword=メタ認知
en-keyword=メタ認知的自覚
kn-keyword=メタ認知的自覚
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=20230324
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=CCN3の関節軟骨における発現は、年齢、荷重の有無に関わらず変形性股関節症と相関する
kn-title=Elevated expression of CCN3 in articular cartilage induces osteoarthritis in hip joints irrespective of age and weight bearing
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=HIROSEKazuki
en-aut-sei=HIROSE
en-aut-mei=Kazuki
kn-aut-name=廣瀬一樹
kn-aut-sei=廣瀬
kn-aut-mei=一樹
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=20220922
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=小児心臓外科における心肺バイパスにおける平均動脈圧と局所脳酸素飽和度との相関　
kn-title=Correlation between Mean Arterial Pressure and Regional Cerebral Oxygen Saturation on Cardiopulmonary Bypass in Pediatric Cardiac Surgery
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=PANYU
en-aut-sei=PAN
en-aut-mei=YU
kn-aut-name=潘禹
kn-aut-sei=潘
kn-aut-mei=禹
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=180
cd-vols=
no-issue=
article-no=
start-page=17
end-page=26
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=20220826
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Psychological Safety in the Teachers’ Room: Investigation of Interpersonal Risks that Hinder Teachers’ Collaboration
kn-title=職員室の心理的安全性 ―教師の協働を阻む対人関係リスクに関する検討―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=本研究では，学校の教師を対象に心理的安全性とそれを阻害する対人関係リスク（率直な発言や意見表明に伴う不安）の実態を把握し，両者の関連について実証的に検討した。Web調査会社の登録モニタから公立学校の常勤教諭を抽出し，インターネットを通じた調査により783 名から有効回答が得られた（小学校338 名，中学校244 名，高等学校201 名）。相関分析により，心理的安全性と対人関係リスクの間には，予測通りの負の関連が確認された。詳細を吟味するために重回帰分析を行ったところ，「無知」「ネガティブ」「邪魔をする人」だと思われる不安が，心理的安全性を阻害することが示唆された。さらに学校種別の分析から，小学校では「邪魔をする人」だと思われる不安，中学校・高等学校では「ネガティブ」だと思われる不安が，心理的安全性を阻害する主要な対人関係リスクであることが示唆された。
en-copyright=
kn-copyright=

en-aut-name=MisawaRyo
en-aut-sei=Misawa
en-aut-mei=Ryo
kn-aut-name=三沢良
kn-aut-sei=三沢
kn-aut-mei=良
aut-affil-num=1
ORCID=

en-aut-name=KamadaMasafumi
en-aut-sei=Kamada
en-aut-mei=Masafumi
kn-aut-name=鎌田雅史
kn-aut-sei=鎌田
kn-aut-mei=雅史
aut-affil-num=2
ORCID=

affil-num=1
en-affil=Faculty of Education, Okayama University
kn-affil=岡山大学学術研究院教育学域

affil-num=2
en-affil=Department of Infant Education, Shujitsu Junior College
kn-affil=就実短期大学幼児教育学科
en-keyword=心理的安全性
kn-keyword=心理的安全性
en-keyword=教師
kn-keyword=教師
en-keyword=協働
kn-keyword=協働
en-keyword=対人関係リスク
kn-keyword=対人関係リスク
END

start-ver=1.4
cd-journal=joma
no-vol=6
cd-vols=
no-issue=
article-no=
start-page=8
end-page=19
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20211230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An Analysis on the Correlation between TOEIC L&R Online Test and GTEC Test
kn-title=TOEIC L&Rオンライン試験とGTECテストの相関関係に関する一考察
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=本研究では、TOEICL&R オンライン試験とGTECAcademic 2技能テストのスコアの相関分析を行った結果を考察し、加えて、岡山大学が独自に開発したCan-Doリストを用いたアンケート結果も報告する。2021年4月に、岡山大学入学者2258名が全学統一GTEC2技能テストを受験し、そのうち96名がTOEICL&Rオンライン試験を受験した。TOEICL&Rオンライン試験の総合得点とGTEC2技能テストの総合得点の相関分析では、中程度の相関が認められた。さらに、約2300名の大学入学時における英語レベルを経年比較に基づき考察すると、従来のTOEIC L&R試験（マークシート式）とTOEIC L&R オンライン試験では、TOEICL&Rオンライン試験のスコアが高めに出る傾向が確認された。コロナ禍において、オンライン試験の需要が高まる中、2020年4月から実施できるようになったTOEIC L&Rオンライン試験が、今後、大学生の英語力を測る新たな指標としての外部検定試験の候補となるかどうか検討することを目的として、GTECテストと比較しながら詳細に報告する。
en-copyright=
kn-copyright=

en-aut-name=TeranishiMasako
en-aut-sei=Teranishi
en-aut-mei=Masako
kn-aut-name=寺西雅子
kn-aut-sei=寺西
kn-aut-mei=雅子
aut-affil-num=1
ORCID=

en-aut-name=OtoshiJunko
en-aut-sei=Otoshi
en-aut-mei=Junko
kn-aut-name=大年順子
kn-aut-sei=大年
kn-aut-mei=順子
aut-affil-num=2
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=剣持淑
kn-aut-sei=剣持
kn-aut-mei=淑
aut-affil-num=3
ORCID=

en-aut-name=OginoMasaru
en-aut-sei=Ogino
en-aut-mei=Masaru
kn-aut-name=荻野勝
kn-aut-sei=荻野
kn-aut-mei=勝
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学全学教育・学生支援機構

affil-num=2
en-affil=
kn-affil=岡山大学 全学教育・学生支援機構

affil-num=3
en-affil=
kn-affil=岡山大学全学教育・学生支援機構

affil-num=4
en-affil=
kn-affil=岡山大学全学教育・学生支援機構
en-keyword=TOEICオンライン試験
kn-keyword=TOEICオンライン試験
en-keyword=GTEC
kn-keyword=GTEC
en-keyword=Can-Doリスト
kn-keyword=Can-Doリスト
en-keyword=自己評価
kn-keyword=自己評価
END

start-ver=1.4
cd-journal=joma
no-vol=12
cd-vols=
no-issue=
article-no=
start-page=151
end-page=164
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=20220330
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=How to think of junior high school students about “The Period for Integrated Studies” - Relationship between the fulfillment of school life and subject learning and the competencies acquired by taking “The Period for Integrated Studies” -
kn-title=「総合的な学習の時間」に対する中学生のとらえかた -学校生活・教科学習の充実度と総学で身につく資質能力の関係-
en-subtitle=
kn-subtitle=
en-abstract=This study clarifies how junior high school students perceive “The Period for Integrated Studies”. Third-year students in the first half of the secondary school are the subjects of this survey. This Secondary School is working on a six-year integrated education that is conscious of the connection with the second half of secondary school. The school has a curriculum centered on “The Period for Integrated Studies” with the goal of equipping students with seven key competencies. In the third grade, they are supposed to set their own issues related to “the way of life” , devise solutions, and summarize the obtained results in papers and posters. In this survey, I asked about the degree of fulfillment of third-year junior high school students in school life, the willingness to work on subject classes, and the degree of understanding of the content of the classes. In addition, the relationship between these results and the theme setting of “problem research”, the degree of fulfillment of each research plan, and the competencies and abilities that they feel “acquired” through “problem research” was examined. It was clarified that the students who were able to make a fulfilling research plan and set high-quality research subjects were more satisfied with their school life, motivated to take lessons in the subject, and understood the contents of the lessons.
kn-abstract=本稿では「総合的な学習の時間」に対する中学生のとらえかたを学校社会学的視点から明らかにする。対象は中等教育学校前期課程の３年生である。同校では後期課程との接続を意識した六年一貫教育に取り組んでいる。７つのキー・コンピテンシーを設定し「課題研究（＝総合的な学習（探究）の時間）」を柱とする教育課程を編成している。３年生は「自己の生き方」に関わる課題を自ら設定し，解決方法を工夫して取り組み，得られた成果を論文及びポスターにまとめ，発表することになっている。調査では学校生活の充実度や教科の授業への意欲及び授業内容の理解度を尋ねた。また，それらと「課題研究」のテーマ設定や計画の充実度，「課題研究」を通して「身についた」と感じる資質能力との関係を検討した。計画の充実度や設定したテーマの質と，学校生活への満足度や教科の授業に対する意欲及び授業内容の理解度との間には明確な相関が見られることが明らかとなった。
en-copyright=
kn-copyright=

en-aut-name=TakahataHiroshi
en-aut-sei=Takahata
en-aut-mei=Hiroshi
kn-aut-name=��旗浩志
kn-aut-sei=��旗
kn-aut-mei=浩志
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Center for Teacher Education and Development, Okayama University
kn-affil=岡山大学教師教育開発センター
en-keyword=総合的な学習の時間(The Period for Integrated Studies)
kn-keyword=総合的な学習の時間(The Period for Integrated Studies)
en-keyword=課題研究（探究学習）(“problem research”)
kn-keyword=課題研究（探究学習）(“problem research”)
en-keyword=資質能力(competencies)
kn-keyword=資質能力(competencies)
en-keyword=中等教育学校(Secondary School)
kn-keyword=中等教育学校(Secondary School)
END

start-ver=1.4
cd-journal=joma
no-vol=21
cd-vols=
no-issue=
article-no=
start-page=17
end-page=35
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=20220318
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A Study of Correlation Between Economic Development Efficiency and Logistics Development in Xinjiang China Based on the DEA-Malmquist Index
kn-title=DEA-Malmquist Indexに基づく中国新疆における経済発展効率と物流機能充実の相関性研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=XUEYuyang
en-aut-sei=XUE
en-aut-mei=Yuyang
kn-aut-name=薛雨陽
kn-aut-sei=薛
kn-aut-mei=雨陽
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院社会文化科学研究科博士後期課程
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210924
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=明細胞癌成分を含む子宮体癌混合癌においてDNAミスマッチ修復タンパク欠損とp53変異は年齢と相関する
kn-title=DNA mismatch repair deficiency and p53 abnormality are age-related events in mixed endometrial carcinoma with a clear cell component
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=IdaNaoyuki
en-aut-sei=Ida
en-aut-mei=Naoyuki
kn-aut-name=依田尚之
kn-aut-sei=依田
kn-aut-mei=尚之
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=27
cd-vols=
no-issue=
article-no=
start-page=11
end-page=20
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210312
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=数学的モデリングを用いた授業の提案
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=日本の中学生・高校生は数学の力が国際的に高い水準にあるにもかかわらず現実世界との関連を充分理解しておらず、入学試験以外の面に数学を学ぶ意義や社会における数学との有用性をあまり感じていない生徒が多いといわれる(北澤・浜野,2000)。さらに、近年では、大学入試が「大学入試センター試験」から「大学入学共通テスト」に名前を変え、日常生活と結び付けた問題で知識を活用する能力や思考力を問うものが増えてきている。この様な近年の動向の中で、筆者は、数学的モデリングを教材として授業に取り入れることで、数学を用いた課題解決によって、生徒に数学を活用することの有用性や課題解決のぷろせすを感じさせる授業を提案する。今回提案する授業の教材は、「コンビニにおける在庫の仕入れ方」である。様々な状況のモデルに対して、いくつかの仕入れ方を検討していく。その上で、授業に適したモデルについても考察していく。
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=河瀬敦帆
kn-aut-sei=河瀬
kn-aut-mei=敦帆
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
en-keyword=モデリング教材
kn-keyword=モデリング教材
en-keyword=在庫管理
kn-keyword=在庫管理
en-keyword=自己相関係数
kn-keyword=自己相関係数
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=アルカリ超酸化物AO2のπ電子磁性と分子配列・軌道秩序の相関に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=MiyajimaMizuki
en-aut-sei=Miyajima
en-aut-mei=Mizuki
kn-aut-name=宮島瑞樹
kn-aut-sei=宮島
kn-aut-mei=瑞樹
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Natural Science and Technology, Okayama university
kn-affil=岡山大学大学院自然科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=11
cd-vols=
no-issue=
article-no=
start-page=75
end-page=88
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210322
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The E?ects of Taking a Class on Knowledge about Sexual and Gender Minorities and Homophobia
kn-title=性的マイノリティに関する授業が性的マイノリティへの知識や受容感に及ぼす影響 : 性的マイノリティに関する授業の前後で
en-subtitle=
kn-subtitle=
en-abstract=The purpose of this study is to clarify the effects of taking a class on knowledge about sexual and gender minorities, confidence in one's own knowledge, and levels of homophobia. We measured the amount of knowledge students had about sexual and gender minorities, students’ confidence in answering the questionnaires correctly, and their levels of homophobia. The results showed that taking a class about sexual and gender minorities significantly increased the amount of knowledge students had about sexual and gender minorities and decreased their homophobia. However, the effect size in the level of homophobia was very small. As for the students’ confidence of their correct answers, before the class, those who had incorrect knowledge about sexual and gender minorities were more confident in their knowledge, but after the class, those who had correct knowledge were more confident in their knowledge, a positive correlation. Based on these results, it is necessary to find an effective way to decrease homophobia. 
kn-abstract=本研究の目的は，性的マイノリティへの関心やレディネスが備わっていない場合であっても授業を受けることにより性的マイノリティへの受容感や知識及び自身の知識に対する自信が変化するかどうかを明らかにすることである。方法は，教員志望の学生を対象に 100分の授業を実施した。調査項目は，性的マイノリティに関する知識量および正答確信度と同性愛者受容感尺度であった。結果は，授業を受けることで，有意に性的マイノリティに関する知識量が増え，同性愛者への受容感が高まることが分かった。しかし，受容感に対する授業の効果量は僅かであった。正答確信度に関しては，授業前は，誤った知識をもっている人ほど自分の知識に自信をもっていたが，授業後は，正しい知識を持っている人ほど自分の知識に自信を持っているという正の相関へ転じた。以上の結果から，性的マイノリティに対する受容感を高める効果的な授業の方法を模索していく必要があると考えられた。 
en-copyright=
kn-copyright=

en-aut-name=NODAYukina
en-aut-sei=NODA
en-aut-mei=Yukina
kn-aut-name=野田夕月奈
kn-aut-sei=野田
kn-aut-mei=夕月奈
aut-affil-num=1
ORCID=

en-aut-name=YAMADATsuyoshi
en-aut-sei=YAMADA
en-aut-mei=Tsuyoshi
kn-aut-name=山田剛史
kn-aut-sei=山田
kn-aut-mei=剛史
aut-affil-num=2
ORCID=

en-aut-name=OHMORIIori
en-aut-sei=OHMORI
en-aut-mei=Iori
kn-aut-name=大守伊織
kn-aut-sei=大守
kn-aut-mei=伊織
aut-affil-num=3
ORCID=

affil-num=1
en-affil=Student at the Graduate School of Education, Okayama University
kn-affil=岡山大学大学院教育学研究科大学院生

affil-num=2
en-affil=Graduate School of Urban Social and Cultural Studies, Yokohama City University
kn-affil=横浜市立大学都市社会文化研究科

affil-num=3
en-affil=Graduate School of Education, Okayama University
kn-affil=岡山大学大学院教育学研究科
en-keyword=性的マイノリティ (sexual and gender minority)
kn-keyword=性的マイノリティ (sexual and gender minority)
en-keyword=性の多様性 (diversity of sexuality)
kn-keyword=性の多様性 (diversity of sexuality)
en-keyword=教育 (education)
kn-keyword=教育 (education)
END

start-ver=1.4
cd-journal=joma
no-vol=11
cd-vols=
no-issue=
article-no=
start-page=43
end-page=57
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210322
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The E?ects of Teachers? Beliefs on their Autonomous Learning Attitudes: Implications for Professional Growth.
kn-title=教師のビリーフが自律的な学習姿勢に及ぼす影響―職能成長への示唆―
en-subtitle=
kn-subtitle=
en-abstract=This study examined the effects of teachers’ beliefs on their autonomous learning attitudes. A questionnaire survey administered to in-service teachers in Japanese public elementary schools received 77 responses. The following four aspects of teachers’ autonomous learning attitudes were measured using scales based on previous findings: “incorporating colleagues’ experiences,” “considering children’s and parents’ perspectives,” “challenging attitude,” and “self-reflection.” Concerning teachers’ beliefs, three factors were extracted through a factor analysis: “ideal vision of school education,” “emphasis on discipline,” and “authority orientation.” The correlation analyses showed that the belief concerning the “ideal vision of school education” was positively related to each aspect of an autonomous learning attitude. Additionally, multiple regression analyses using interaction terms revealed that the positive effect of the “ideal vision of school education” belief on an autonomous learning attitude was moderated by the “emphasis on discipline” belief. That is, the “ideal vision of school education” only promoted autonomous learning attitudes when the “emphasis on discipline” belief was strong. Implications regarding the professional growth of teachers were discussed. 
kn-abstract=本研究は，教師のビリーフが自律的な学習姿勢に及ぼす影響について検討した。公立小学校の現職教員へ質問紙調査を行い，77 名から回答を得た。教師の自律的な学習姿勢については，既存尺度に基づき「同僚の経験の取り入れ」，「児童・保護者の視点の考慮」，「前向きな挑戦姿勢」，「自己省察」の 4 つの側面を測定した。教師のビリーフについては，因子分析により「学校教育の理想像」，「規律重視」，「権威志向」の 3 つの側面を表す因子を抽出した。相関分析の結果では，「学校教育の理想像」ビリーフが自律的な学習姿勢の各側面と正の関連を示した。また交互作用項を含む重回帰分析の結果，「学校教育の理想像」が学習姿勢に及ぼす効果は，「規律重視」ビリーフに調整されることが示された。すなわち，「規律重視」が高い場合にのみ，「学校教育の理想像」は学習姿勢を促進していた。得られた知見を基に，教師の職能成長に関する示唆を考察した。
en-copyright=
kn-copyright=

en-aut-name=MISAWARyo
en-aut-sei=MISAWA
en-aut-mei=Ryo
kn-aut-name=三沢良
kn-aut-sei=三沢
kn-aut-mei=良
aut-affil-num=1
ORCID=

en-aut-name=NABETAMizuki
en-aut-sei=NABETA
en-aut-mei=Mizuki
kn-aut-name=鍋田瑞希
kn-aut-sei=鍋田
kn-aut-mei=瑞希
aut-affil-num=2
ORCID=

en-aut-name=MORIYASUFumihiko
en-aut-sei=MORIYASU
en-aut-mei=Fumihiko
kn-aut-name=森安史彦
kn-aut-sei=森安
kn-aut-mei=史彦
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院教育学研究科

affil-num=2
en-affil=
kn-affil=伊予市立伊予小学校

affil-num=3
en-affil=
kn-affil=岡山大学教育学部附属中学校
en-keyword=小学校教師 (elementary school teacher)
kn-keyword=小学校教師 (elementary school teacher)
en-keyword=ビリーフ (belief)
kn-keyword=ビリーフ (belief)
en-keyword=自律的学習 (autonomous learning)
kn-keyword=自律的学習 (autonomous learning)
en-keyword=職能成長 (professional growth)
kn-keyword=職能成長 (professional growth)
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2020
dt-pub=20200925
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=粘液繊維肉腫における分泌型micro-RNA1260bの臨床相関性と浸潤機序の解析
kn-title=Clinical relevance and functional significance of cell-free microRNA-1260b expression profiles in infiltrative myxofibrosarcoma
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=MoritaTakuya
en-aut-sei=Morita
en-aut-mei=Takuya
kn-aut-name=森田卓也
kn-aut-sei=森田
kn-aut-mei=卓也
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=7
article-no=
start-page=41
end-page=56
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1979
dt-pub=19790301
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=長編小説の鑑賞試論――事象（心象）と人間像の相関把握へのアプローチ――”阿部知二「冬の宿」を素材に”
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=上村敦之
kn-aut-sei=上村
kn-aut-mei=敦之
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=津山商業高等学校
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=24
article-no=
start-page=74
end-page=64
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=19960331
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=言表事態とナイ文の意味的相関性について――狂言資料における――
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=久山佳子
kn-aut-sei=久山
kn-aut-mei=佳子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=30
article-no=
start-page=92
end-page=101
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2002
dt-pub=20020331
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=『とはずがたり』における地の文と和歌との相関性について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=金粉淑
kn-aut-sei=金
kn-aut-mei=粉淑
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=東亜大学校日語日文学科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2020
dt-pub=20200325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=総合内科外来患者における抑うつ状態と胃食道逆流症状の相関関係について
kn-title=Correlations between Depressive Condition and Gastroesophageal Reflux Symptoms in Patients Visiting a Department of General Medicine
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=SuganamiYu
en-aut-sei=Suganami
en-aut-mei=Yu
kn-aut-name=菅波由有
kn-aut-sei=菅波
kn-aut-mei=由有
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=10
cd-vols=
no-issue=
article-no=
start-page=27
end-page=37
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2020
dt-pub=20200320
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The Relationship between Word Play and Reading Fluency of Hiragana Words in Preschool Children
kn-title=年長児におけることば遊びとひらがな単語読字の 流暢性との関連
en-subtitle=
kn-subtitle=
en-abstract=in preschool children. Forty 5-6 aged children participated in the study, and we assessed on three skills: orthographic knowledge of long-vowel words, reading fluency, word play. The results of correlation analysis showed that orthographic knowledge of long-vowel words was moderately related to reading fluency. In addition, the results of multiple regression analysis showed that age and scores of word play variables were predictors of reading fluency. The findings provide further evidence for the relationship between reading fluency and word play that were demanded th e skills of phonological manipulatio n and word search.
kn-abstract= 本研究は，年長児のことば遊び，長音表記知識，およびひらがな単語読字の流暢性との関連を明らかにすることを目的とした。年長児40 名を対象に，文字を使ったことば遊びである“ことばのかくれんぼゲーム”，かな読み中後期の発達課題である，ひらがな長音単語の表記知識課題，ひらがな単語速読課題を実施した。各課題の相関から，ひらがな単語速読成績と長音表記選択課題の分節回答成績で有意な関連が認められた。また，ことばのかくれんぼゲーム成績，長音表記選択成績，月齢を独立変数，ひらがな単語速読成績を従属変数とした重回帰分析の結果，ことばのかくれんぼゲームの「部分文字列」成績と月齢が有意な予測変数として抽出された。本研究から，年長児におけるひらがな単語読字の流暢性には，ことばの音韻操作を駆使してことばを見つける力や，有意味な文字列をすばやく見つける力を必要とされるような，ことば遊びが関与することが示唆された。
en-copyright=
kn-copyright=

en-aut-name=YOKOYAMAMoe
en-aut-sei=YOKOYAMA
en-aut-mei=Moe
kn-aut-name=横山萌
kn-aut-sei=横山
kn-aut-mei=萌
aut-affil-num=1
ORCID=

en-aut-name=TANJITakayuki
en-aut-sei=TANJI
en-aut-mei=Takayuki
kn-aut-name=丹治敬之
kn-aut-sei=丹治
kn-aut-mei=敬之
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=佐用町立上月小学校

affil-num=2
en-affil=
kn-affil=岡山大学大学院教育学研究科
en-keyword=年長児 (Preschool children)
kn-keyword=年長児 (Preschool children)
en-keyword=ひらがな単語の読字 (Hiragana Word Reading)
kn-keyword=ひらがな単語の読字 (Hiragana Word Reading)
en-keyword=ことば遊び (Word Play)
kn-keyword=ことば遊び (Word Play)
en-keyword=流暢性 (Fluency)
kn-keyword=流暢性 (Fluency)
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=複素多環式化合物の合成および分子構造と半導体特性の相関解明
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=NishinagaShuhei
en-aut-sei=Nishinaga
en-aut-mei=Shuhei
kn-aut-name=西永周平
kn-aut-sei=西永
kn-aut-mei=周平
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=岡山大学大学院自然科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=スピン分解電子構造に基づくハーフメタル強磁性体の強相関効果の研究
kn-title=Studies on Strong Correlation Effects in Half-Metallic Ferromagnets based on Spin-Resolved Electronic Structure
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=FujiwaraHirokazu
en-aut-sei=Fujiwara
en-aut-mei=Hirokazu
kn-aut-name=藤原弘和
kn-aut-sei=藤原
kn-aut-mei=弘和
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=岡山大学大学院自然科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=好酸球性副鼻腔炎における黄色ブドウ球菌エンテロトキシンBの刺激によるIL-10産生障害と重症度との相関について
kn-title=Association between impaired IL-10 production following exposure to
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=HarunaTakenori
en-aut-sei=Haruna
en-aut-mei=Takenori
kn-aut-name=春名威範
kn-aut-sei=春名
kn-aut-mei=威範
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=9
cd-vols=
no-issue=
article-no=
start-page=251
end-page=257
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190320
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Study of “Confusion after the Entrance to Higher Education” �W : Grasp of the Consultation Situation for Second-Year Undergraduates
kn-title=「大1コンフュージョン」の実際（第4報） : 大学2年目の学生を対象とした相談状況とその検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract= 本研究は，現状の支援体制が「大1コンフュージョン」等の解消や緩和にどの程度寄与できているのかについて検討することを目的とした。2018年12月に実施した調査では，大学生活が1年半以上経過した2年目の学生を対象に，「大1コンフュージョン」項目群と，既存の相談先，意欲低下領域尺度，単位取得状況を聞き，その相関について分析と考察を行った。この結果，単位取得に影響が少ない範囲で対処できている学生は，戸惑いや困難が生じた場合，友人や家族等を中心に相談し，援助要請をすることによって深刻な状況を回避していると推察された。また，「大1コンフュージョン」が継続している学生は，友人や家族を中心とした援助を得ながらどうにか必要な単位取得は進められている場合であっても，大学や学業に対する意欲が低下する状況になっていると考えられた。
en-copyright=
kn-copyright=

en-aut-name=IketaniKosuke
en-aut-sei=Iketani
en-aut-mei=Kosuke
kn-aut-name=池谷航介
kn-aut-sei=池谷
kn-aut-mei=航介
aut-affil-num=1
ORCID=

en-aut-name=HaradaShin
en-aut-sei=Harada
en-aut-mei=Shin
kn-aut-name=原田新
kn-aut-sei=原田
kn-aut-mei=新
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学全学教育・学生支援機構学生総合支援センター

affil-num=2
en-affil=
kn-affil=岡山大学全学教育・学生支援機構学生総合支援センター
en-keyword=大1コンフュージョン
kn-keyword=大1コンフュージョン
en-keyword=高大接続
kn-keyword=高大接続
en-keyword=支援体制
kn-keyword=支援体制
END

start-ver=1.4
cd-journal=joma
no-vol=9
cd-vols=
no-issue=
article-no=
start-page=243
end-page=250
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190320
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Study of “Confusion after the Entrance to Higher Education” �V The Relationships among “Confusion after the entrance to Higher Education”, Life Skills, Passivity Area, and Psychological Stress Response.
kn-title=「大1コンフュージョン」の実際（第3報） : ライフスキル，意欲低下，心理的ストレス反応との関連
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract= 本研究では，大1コンフュージョンに陥りやすい大学新入生の様々な特徴について調べることを目的に，日常生活スキル尺度（大学生版），意欲低下領域尺度，心理的ストレス反応尺度との関連について検討した。相関分析の結果，大1コンフュージョン（大学生活全般）は，8種類のライフスキルおよび「学業意欲低下」とはほぼ無関連であったが，「授業意欲低下」，「大学意欲低下」および3種類のストレス反応とは中程度の正の相関がみられた。また大1コンフュージョン（一人暮らし）は，8種類のライフスキルおよび「学業意欲低下」，「大学意欲低下」，「不機嫌・怒り」とはほぼ無関連であったが，「授業意欲低下」，「抑うつ・不安」，「無気力」とは弱い正の相関がみられた。今後，スケジュール管理スキルや援助要請スキル等，今回測定できていないが大学適応に重要と考えられるライフスキルと，大1コンフュージョンとの関連についても検討を行う必要がある。
en-copyright=
kn-copyright=

en-aut-name=HaradaShin
en-aut-sei=Harada
en-aut-mei=Shin
kn-aut-name=原田新
kn-aut-sei=原田
kn-aut-mei=新
aut-affil-num=1
ORCID=

en-aut-name=IketaniKosuke
en-aut-sei=Iketani
en-aut-mei=Kosuke
kn-aut-name=池谷航介
kn-aut-sei=池谷
kn-aut-mei=航介
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学全学教育・学生支援機構学生総合支援センター

affil-num=2
en-affil=
kn-affil=岡山大学全学教育・学生支援機構学生総合支援センター
en-keyword=大1コンフュージョン
kn-keyword=大1コンフュージョン
en-keyword=高大接続
kn-keyword=高大接続
en-keyword=ライフスキル
kn-keyword=ライフスキル
en-keyword=意欲低下
kn-keyword=意欲低下
en-keyword=ストレス反応
kn-keyword=ストレス反応
END

start-ver=1.4
cd-journal=joma
no-vol=9
cd-vols=
no-issue=
article-no=
start-page=99
end-page=108
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190320
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A Study on the Change of Image of Student Guidance by Trainee Teachers Before and After University Lecture
kn-title=全学教職課程履修学生の講義前後における生徒指導イメージの変容の検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract= 本研究の目的は，全学教職課程履修学生の生徒指導に関する講義の前後における生徒指導イメージの変容を検討することであった。そのため，教育学部以外に所属し教職課程を履修する学生のうち，生徒指導に関する講義を受講する学生を対象に，講義の前後に調査を行い，115名の有効回答が得られた。その結果，（１）生徒指導イメージの8因子のうち，「指導の難しさ」「一方的な指導」「個に応じたきめ細かな指導」「間違いを正す」「やりがい」の5因子が有意に高まり，学生の生徒指導イメージが講義を通して深まっている可能性があること，（２）学生の生徒指導イメージの因子間相関を講義の前後で算出した結果，講義後に相関係数が有意に転じたものが多く，学生の生徒指導イメージが講義後により多面的になった可能性があること，が主に示唆された。そして，講義の充実度や生徒指導力の高まり度などの補足データと併せて結果が考察された。
en-copyright=
kn-copyright=

en-aut-name=MishimaTomotaka
en-aut-sei=Mishima
en-aut-mei=Tomotaka
kn-aut-name=三島知剛
kn-aut-sei=三島
kn-aut-mei=知剛
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学教師教育開発センター
en-keyword=生徒指導イメージ
kn-keyword=生徒指導イメージ
en-keyword=全学教職課程履修学生
kn-keyword=全学教職課程履修学生
en-keyword=大学講義
kn-keyword=大学講義
END

start-ver=1.4
cd-journal=joma
no-vol=118
cd-vols=
no-issue=355
article-no=
start-page=103
end-page=108
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2018
dt-pub=201812
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Proposing an Unsupervised Approach to Evaluate Essays Using IDF on Reference Data
kn-title=参照データとidf を利用した事前採点不要な小論文評価手法
en-subtitle=
kn-subtitle=
en-abstract=In this paper, we describe an on-going study of developing an automatic essay-scoring system in Japanese. Essay scoring systems have already been developed and used mainly in English, while not many previous studies have been done on Japanese essay evaluations. Most of the methods and systems of automatic essay evaluation need not small number of previously human-graded essays for calibrating the parameter of regression functions or parameter of machine learning. The previous studies show the high performance for essay evaluation task, however, it must be not easy to assume large graded essays in, for example, actual tests or entrance examinations. Thus, we take a approach to evaluate Japanese essays without previously human-graded essays but with assuming reference data related to essay questions. The proposed method is a simple one, that is, evaluating the essays with co-occurrences with the reference data in their words or morphemes. In the method technical terms would be given high scores using neologd dictionary and idf values. Experimental results show that the proposed method works well in our developing Japanese mock trial writing tests. Key words automatic scoring of essays, human annotation, supporting
kn-abstract=大学入試において2020 年から記述式問題が導入されることから記述式の問題を自動で採点する手法の開発が求められている．本論では，エッセイタイプの小論文課題を対象に，課題に関連する参照データとWikipedia 全文から作成したidf を利用した事前採点不要な自動採点手法を提案する．先行研究において，日本語小論文を対象とした自動採点では，多くの事前採点が必要となり，実際の数百人規模の試験では利用することが難しいと考えられる．そこで本研究では，事前採点が不要な小論文採点手法を提案する．また，小論文の模擬試験を実施して小論文データを構築する．構築した小論文データに対して採点手法を用い，実験を行い評価する．また小論文データの人手による採点に対しても評価を行う．評価実験の結果neologd 辞書を利用した形態素解析器を用いて， idf 値を利用した形態素の一致数が，人手の評価値と相関が高いことを示す．
en-copyright=
kn-copyright=

en-aut-name=OhnoMasayuki
en-aut-sei=Ohno
en-aut-mei=Masayuki
kn-aut-name=大野雅幸
kn-aut-sei=大野
kn-aut-mei=雅幸
aut-affil-num=1
ORCID=

en-aut-name=TakeuchiKoichi
en-aut-sei=Takeuchi
en-aut-mei=Koichi
kn-aut-name=竹内孔一
kn-aut-sei=竹内
kn-aut-mei=孔一
aut-affil-num=2
ORCID=

en-aut-name=MotojinKota
en-aut-sei=Motojin
en-aut-mei=Kota
kn-aut-name=泉仁宏太
kn-aut-sei=泉仁
kn-aut-mei=宏太
aut-affil-num=3
ORCID=

en-aut-name=ObataYuya
en-aut-sei=Obata
en-aut-mei=Yuya
kn-aut-name=小畑友也
kn-aut-sei=小畑
kn-aut-mei=友也
aut-affil-num=4
ORCID=

en-aut-name=TaguchiMasahiro
en-aut-sei=Taguchi
en-aut-mei=Masahiro
kn-aut-name=田口雅弘
kn-aut-sei=田口
kn-aut-mei=雅弘
aut-affil-num=5
ORCID=

en-aut-name=InadaYoshihiko
en-aut-sei=Inada
en-aut-mei=Yoshihiko
kn-aut-name=稲田佳彦
kn-aut-sei=稲田
kn-aut-mei=佳彦
aut-affil-num=6
ORCID=

en-aut-name=IizukaMasaya
en-aut-sei=Iizuka
en-aut-mei=Masaya
kn-aut-name=飯塚誠也
kn-aut-sei=飯塚
kn-aut-mei=誠也
aut-affil-num=7
ORCID=

en-aut-name=AboTatsuhiko
en-aut-sei=Abo
en-aut-mei=Tatsuhiko
kn-aut-name=阿保達彦
kn-aut-sei=阿保
kn-aut-mei=達彦
aut-affil-num=8
ORCID=

en-aut-name=UedaHitoshi
en-aut-sei=Ueda
en-aut-mei=Hitoshi
kn-aut-name=上田均
kn-aut-sei=上田
kn-aut-mei=均
aut-affil-num=9
ORCID=

affil-num=1
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=岡山大学大学院自然科学研究科

affil-num=2
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=岡山大学大学院自然科学研究科

affil-num=3
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=岡山大学大学院自然科学研究科

affil-num=4
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=岡山大学大学院自然科学研究科

affil-num=5
en-affil=Graduate School of Humanities and Social Science, Okayama University
kn-affil=岡山大学院社会文化科学研究科

affil-num=6
en-affil=Graduate School of Education, Okayama University
kn-affil=岡山大学院教育学研究科

affil-num=7
en-affil=Institute for Education and Student Services, Okayama University
kn-affil=岡山大学全学教育・学生支援機構

affil-num=8
en-affil=Institute for Education and Student Services, Okayama University
kn-affil=岡山大学全学教育・学生支援機構

affil-num=9
en-affil=Institute for Education and Student Services, Okayama University
kn-affil=岡山大学全学教育・学生支援機構
en-keyword=自動採点 (automatic scoring of essays)
kn-keyword=自動採点 (automatic scoring of essays)
en-keyword=アノテーション (human annotation)
kn-keyword=アノテーション (human annotation)
en-keyword=採点支援 (supporting system of essay evaluation)
kn-keyword=採点支援 (supporting system of essay evaluation)
en-keyword=idf
kn-keyword=idf
en-keyword=neologd
kn-keyword=neologd
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2018
dt-pub=20180323
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=コクヌストモドキの歩行移動に対する人為選択への直接反応と相関反応
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=MatumuraKentaro
en-aut-sei=Matumura
en-aut-mei=Kentaro
kn-aut-name=松村健太郎
kn-aut-sei=松村
kn-aut-mei=健太郎
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=岡山大学大学院環境生命科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=2
cd-vols=
no-issue=
article-no=
start-page=107
end-page=116
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=20171230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Essay on Pluralistic Self-assessment of Career Education �U : From the evaluation results of the 2016 school year
kn-title=キャリア教育における多元的自己評価試論�U : 2016 年度の評価結果から
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=　キャリア教育における教育効果を測るとき、評価項目を多元的に構築した試みを踏まえて、実際に2016 年度第4 学期に2 つのキャリア教育授業科目で評価測定を行った。そして、この評価測定を踏まえて、多元的自己評価の有用性について検証を試みた。特に、本稿では教育目標に関して認知的に自己評価できる領域と非認知能力を自己評価できる領域から個々の学生の受講前−受講後の変化を抽出して、領域間の相関関係について検討した。その結果、カリキュラム内で予め設定した関連づけられる評価項目においては、領域間の相関関係を見出すことができた。また、関連づけられない評価項目との相関関係についての検討も試みた。以上から、多元的自己評価に関する一定の有効性を提起できたとともに、そこからの今後の課題についても整理することができた。
en-copyright=
kn-copyright=

en-aut-name=NakayamaYoshikazu
en-aut-sei=Nakayama
en-aut-mei=Yoshikazu
kn-aut-name=中山芳一
kn-aut-sei=中山
kn-aut-mei=芳一
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Institute for Education and Student Services, Okayama University
kn-affil=岡山大学全学教育・ 学生支援機構
END

start-ver=1.4
cd-journal=joma
no-vol=106
cd-vols=
no-issue=
article-no=
start-page=27
end-page=32
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=20170201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=トウガラシ（Capsicum baccatum）における カプサイシノイド含量の変異とその非辛味系統
kn-title=Variations in capsaicinoid contents in the chili pepper (Capsicum baccatum) and its non-pungent accessions
en-subtitle=
kn-subtitle=
en-abstract=　トウガラシ（Capsicum 属）は世界的に重要な香辛料および野菜である．C. baccatum は南米原産のマイナーな栽培種であるが，果色，果形や辛味など果実形質に多様性が認められることから，トウガラシ遺伝資源として注目されている．トウガラシの辛味性についてはC. annuum 種において多くの研究が行われているが，C. baccatum 種においては十分研究されていない．<br>
　本研究では，C. baccatum 36系統について辛味成分カプサイシノイドの含量を調査した．カプサイシノイド含量の幅は0 〜4,258 ? /gDW であった．また果実重と辛味成分含量の間に負の相関が認められた．C. baccatum の辛味は低?中程度であるが，非辛味系統はほとんど認められず，唯一1 系統（‘Kaleidoscope’）が非辛味であった．この非辛味の安定性を調査するために，辛味程度の異なる系統とともに異なる収穫時期におけるカプサイシノイド含量を調査した．<br>
　他のC. baccatum 系統ではカプサイシノイド含量は収穫時期で変化したが，‘Kaleidoscope’ ではいずれの収穫時期でもカプサイシノイドは検出されなかった．本研究で見出された非辛味系統は将来のC. baccatum の育種において有用であろう．
kn-abstract=The chili pepper (Capsicum) is both an important spice and fresh vegetable worldwide. C. baccatum is a lesser known domesticated species that is native to the Andean region. Fruit traits such as color, shape, and pungency markedly vary in this species. C. baccatum has potential as a bioresource for future chili pepper breeding programs. Although extensive studies have been conducted on the pungency of C. annuum, that of C. baccatum has not been examined in as much detail. In the present study, capsaicinoid contents were analyzed in 36 C. baccatum accessions. Capsaicinoid contents ranged between 0 and 4,258 μg/gDW. Furthermore, a negative relationship was observed between capsaicinoid contents and fruit weights. Although the pungency of C. baccatum is regarded as low-mild, very few non-pungent accessions were detected ; only one non-pungent accession (‘Kaleidoscope’) was identified among the C. baccatum accessions examined. In order to validate the stability of non-pungency in the accession, capsaicinoid contents were determined at different harvest dates, along with other accessions with different pungencies. Although capsaicinoid contents in other C. baccatum accessions changed with the picking date, capsaicinoid was not detected in ‘Kaleidoscope’ at any date. The non-pungent accession reported here may be useful for future C. baccatum pepper breeding programs.
en-copyright=
kn-copyright=

en-aut-name=TanakaYoshiyuki
en-aut-sei=Tanaka
en-aut-mei=Yoshiyuki
kn-aut-name=田中義行
kn-aut-sei=田中
kn-aut-mei=義行
aut-affil-num=1
ORCID=

en-aut-name=HaraMotohito
en-aut-sei=Hara
en-aut-mei=Motohito
kn-aut-name=原一仁
kn-aut-sei=原
kn-aut-mei=一仁
aut-affil-num=2
ORCID=

en-aut-name=GotoTanjuro
en-aut-sei=Goto
en-aut-mei=Tanjuro
kn-aut-name=後藤丹十郎
kn-aut-sei=後藤
kn-aut-mei=丹十郎
aut-affil-num=3
ORCID=

en-aut-name=YoshidaYuichi
en-aut-sei=Yoshida
en-aut-mei=Yuichi
kn-aut-name=吉田裕一
kn-aut-sei=吉田
kn-aut-mei=裕一
aut-affil-num=4
ORCID=

en-aut-name=YasubaKen-ichiro
en-aut-sei=Yasuba
en-aut-mei=Ken-ichiro
kn-aut-name=安場健一郎
kn-aut-sei=安場
kn-aut-mei=健一郎
aut-affil-num=5
ORCID=

affil-num=1
en-affil=Graduate School of Environmental and life Science, Okayama University
kn-affil=岡山大学大学院環境生命科学研究科

affil-num=2
en-affil=Graduate School of Environmental and life Science, Okayama University
kn-affil=岡山大学大学院環境生命科学研究科

affil-num=3
en-affil=Graduate School of Environmental and life Science, Okayama University
kn-affil=岡山大学大学院環境生命科学研究科

affil-num=4
en-affil=Graduate School of Environmental and life Science, Okayama University
kn-affil=岡山大学大学院環境生命科学研究科

affil-num=5
en-affil=Graduate School of Environmental and life Science, Okayama University
kn-affil=岡山大学大学院環境生命科学研究科
en-keyword=Bio-resource
kn-keyword=Bio-resource
en-keyword=Fruit shape
kn-keyword=Fruit shape
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=20150630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=胃癌におけるDNAミスマッチ修復およびARID1A蛋白発現異常の臨床病理学意義および相関性
kn-title=ARID1A expression in gastric adenocarcinoma: Clinicopathological significance and correlation with DNA mismatch repair status
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=InadaRyo
en-aut-sei=Inada
en-aut-mei=Ryo
kn-aut-name=稲田涼
kn-aut-sei=稲田
kn-aut-mei=涼
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院
END

start-ver=1.4
cd-journal=joma
no-vol=35
cd-vols=
no-issue=5
article-no=
start-page=1217
end-page=1225
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199209
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=慢性関節リウマチの股関節障害における臼底骨移植を併用した全人工股関節置換術の検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=RAにおいて臼底への骨移植を併用したTHA 23例30関節について,臨床的及びX線学的に評価を行った。1)臨床的評価では疼痛,可動域及び歩行能力の改善がみられ,総合点で術前32.7点から追跡時68.4点に改善した。2)ソケットの傾斜角度は平均43.7°Cで,45±5°の範囲に56.7%が入っていた。3)移植骨の面積は平均233.7mm2で,PAの程度と正の相関がみられた。4)CZの発生率は臼蓋側で60.0%,大腿骨側で46.7%で,1例にlooseningがみられた。臼蓋側のCZの程度と,ソケットの傾斜角度及び移植骨の面積との間に有意差はみられなかった。5)移植骨は術後1年で大多数が癒合したが,脱臼した1例のみcollapseをきたした。癒合時期と移植骨面積との間には相関はみられなかった。以上,RAのTHAに際して,臼底へのsolid boneによる骨移植法は脆弱化した臼底の再建法として有用であった
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=楠戸康通
kn-aut-sei=楠戸
kn-aut-mei=康通
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=81
cd-vols=
no-issue=11
article-no=
start-page=1686
end-page=1693
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1990
dt-pub=199011
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=男子不妊症における精細管内アンドロゲンレセプターの研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=精細管内AR測定法を確立し,その基礎的検討とともに,特発性男子不妊症患者における精細管内ARを測定して,各種パラメーターと比較検討した.1) Total intratubular salt-soluble extractのARのBmaxは,細胞質分画と粗核抽出分画の中間の値を示し,Kdは同levelであった.2)通常の1/5 (40 μl)使用したmicro-receptor assayで,従来のreceptor assayと同levelのBmaxが得られた.3)精細管内ARと外陰部皮膚ARとの相関係数はr=-0.18と密接な関連性はなく,外陰部皮膚ARは男子不妊症のandrogen insensitibityを十分に反映しないと考えられた.4)精子形成能が正常と考えられる22例における検討より,精細管内ARのcut-off値は11 fmol/mg proteinと設定した.5)特発性男子不妊症61例中,精細管内AR低値群は7例と男子不妊症におけるandrogen insensitivityは少ないことが判明した.6) AR低値群のLH, TxLHはAR正常群に比し有意に高値を示したが,T, FSHは両群間に有意差がなく,また精細管内T, DHTとの関連性もないことより,精細管内AR低値群では中枢におけるARに何らかの異常の存在することが示唆された
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=大橋洋三
kn-aut-sei=大橋
kn-aut-mei=洋三
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=154
cd-vols=
no-issue=
article-no=
start-page=57
end-page=63
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=20131125
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Outbreak and process of the performance anxiety for university students
kn-title=大学生を対象とした演奏不安の発生と推移
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=　本研究は，定期演奏会（学生オペラ）と卒業・修了演奏会（独奏部門）に出演した大学生
を対象に，集団と個人の二種類の演奏形態が学生たちにもたらす演奏不安の実態について，
心理的ストレス反応とインタビューによって検討した。心理的ストレス反応は，新版STAI
を用いて本番３ヶ月前から当日まで計４回測定した。その結果，オペラ出演時には状態不安
が大きく変動し，特にキャストに配役された学生たちの本番１週間前と当日の間に有意な違
いが認められた。キャストの不安値は最後の一週間で大きく変動する一方，キャスト以外で
はあまり変動が見られず，高い値のまま推移する傾向にあった。また，独奏を主体とする個
人演奏では，３ヶ月間の状態不安にほとんど変化が見られず高いままであることが明らかに
なった。被験者自身の性格特性に由来する特性不安と状態不安の間に，強い相関は認められ
なかった。
en-copyright=
kn-copyright=

en-aut-name=OgawaYoko
en-aut-sei=Ogawa
en-aut-mei=Yoko
kn-aut-name=小川容子
kn-aut-sei=小川
kn-aut-mei=容子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院教育学研究科　芸術教育学系　音楽教育講座
en-keyword=演奏不安
kn-keyword=演奏不安
en-keyword=心理的ストレス反応
kn-keyword=心理的ストレス反応
en-keyword=状態不安
kn-keyword=状態不安
en-keyword=特性不安
kn-keyword=特性不安
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=20130325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Mucociliary clearance (MC) 評価系の構築とMC−経鼻吸収相関に基づいた経鼻吸収予測システムの開発に関する基礎的研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=InoueDaisuke
en-aut-sei=Inoue
en-aut-mei=Daisuke
kn-aut-name=井上大輔
kn-aut-sei=井上
kn-aut-mei=大輔
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=102
cd-vols=
no-issue=
article-no=
start-page=29
end-page=34
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=20130201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effect of Day Length, Supplemental Lighting Strength, Shading Period and Minimum Night Temperature on Occurrence of Abnormal Inflorescence in Gypsophila paniculata ‘Altair’
kn-title=日長，補光強度，遮光時期および最低夜温がシュッコンカスミソウ ‘アルタイル’の形態異常花序発生に及ぼす影響
en-subtitle=
kn-subtitle=
en-abstract=シュッコンカスミソウ‘アルタイル’の形態異常花序の発生には環境要因が関与していると考えられたので，日長，補光強度，遮光時期および最低夜温が形態異常花序発生に及ぼす影響を調査した．形態異常程度は４種類のパターン (０：正常，１：茎が短いもの，２：２本の茎が癒着，3：ひどく湾曲し変形したもの) に分類し，その影響を受けた小花の割合を求めた．蛍光灯による日長処理（12時間，16時間，20時間，24時間）や白熱灯による日長処理（自然日長，24時間）は形態異常花序発生率に影響を及ぼさなかった．蛍光灯（PPFD 1μmol・m-2・s-1），白熱灯（PPFD 3μmol・m-2・s-1），メタルハライドランプ（PPFD 14μmol・m-2・s-1），高圧ナトリウムランプ（PPFD 48μmol・m-2・s-1）を用いて16時間の補光を行った．異なる光源による光強度でも形態異常発生率に一定の傾向は認められなかった．遮光時期を変えても形態異常発生率に一定の傾向は認められなかった． 最低夜温を15℃に上げると８℃区と比較して15℃区の形態異常発生は大きく減少した．特にパターン２と３の発生率は大幅に低下した．各実験の処理開始から発蕾までの平均夜温（7.1℃，9.0℃，9.2℃，11.6℃，16.4℃）と，パターン３の形態異常発生率（13.1%，8.7%，7.1%，1.1%，0.7%）との間に高い負の相関（R2＝0.849）が認められ，処理開始から発蕾までの平均夜温が高いほど形態異常発生率は低下した．以上のことから，形態異常花序発生には夜間の温度が大きく関与しているのではないかと推察された．
kn-abstract=As occurrence of abnormal inflorescence in Gypsophila paniculata ‘Altair’ is caused by environmental conditions, effects of day length, supplemental lighting strength, shading period and minimum night temperature on occurrence of abnormal inflorescence were investigated. Abnormal inflorescence was classified into four types : normal, pattern 1 (Short-flower stalk), pattern 2 (Coalescent two-flower stalk) and pattern 3 (Looping and irregular-flower stalk). Neither of 12h, 16h, 20h or 24h day length by fluorescent lamp, nor 24h by incandescent lamp affected occurrence of abnormal inflorescence. Effects of four levels of light intensity (fluorescent lamp : PPFD 1μmol・m?2・s?1, incandescent lamp : PPFD 3μmol・m?2・s?1, metal halide lamp : PPFD 14μmol・m?2・s?1 and high-pressure sodium lamp : PPFD 48μmol・m?2・s?1) were examined in 16h photoperiod. Occurrence of abnormal inflorescence was not affected by different light intensities, neither was it affected by shading period. Occurrence of abnormal inflorescence at 15°C was however significantly reduced compared to that at 8°C. In particular, patterns 2 and 3 at 15°C were significantly reduced compared to those at 8°C. There was a strong negative correlation between average night temperature from starting the treatment to flower budding (7.1°C, 9.0°C, 9.2°C, 11.6°C and 16.4°C) and incidence of pattern 3 (13.1%, 8.7%, 7.1%, 1.1% and 0.7%). Therefore, as average night temperature increased, occurrence of abnormal inflorescence decreased. The results show that low night temperature may be the main factor inducing occurrence of abnormal inflorescence.
en-copyright=
kn-copyright=

en-aut-name=YamaguchiNorihito
en-aut-sei=Yamaguchi
en-aut-mei=Norihito
kn-aut-name=山口訓史
kn-aut-sei=山口
kn-aut-mei=訓史
aut-affil-num=1
ORCID=

en-aut-name=GotoTanjuro
en-aut-sei=Goto
en-aut-mei=Tanjuro
kn-aut-name=後藤丹十郎
kn-aut-sei=後藤
kn-aut-mei=丹十郎
aut-affil-num=2
ORCID=

en-aut-name=KobikiKayoko
en-aut-sei=Kobiki
en-aut-mei=Kayoko
kn-aut-name=小日置佳世子
kn-aut-sei=小日置
kn-aut-mei=佳世子
aut-affil-num=3
ORCID=

en-aut-name=OtaniShoko
en-aut-sei=Otani
en-aut-mei=Shoko
kn-aut-name=大谷翔子
kn-aut-sei=大谷
kn-aut-mei=翔子
aut-affil-num=4
ORCID=

en-aut-name=YoshidaYuichi
en-aut-sei=Yoshida
en-aut-mei=Yuichi
kn-aut-name=吉田裕一
kn-aut-sei=吉田
kn-aut-mei=裕一
aut-affil-num=5
ORCID=

affil-num=1
en-affil=
kn-affil=

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=

affil-num=4
en-affil=
kn-affil=

affil-num=5
en-affil=
kn-affil=岡山大学
en-keyword=abnormal inflorescence pattern
kn-keyword=abnormal inflorescence pattern
en-keyword=cut flower form
kn-keyword=cut flower form
en-keyword=environmental factor
kn-keyword=environmental factor
en-keyword=incidence of abnormal inflorescence
kn-keyword=incidence of abnormal inflorescence
en-keyword=low night temperature
kn-keyword=low night temperature
END

start-ver=1.4
cd-journal=joma
no-vol=102
cd-vols=
no-issue=
article-no=
start-page=21
end-page=28
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=20130201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Incidence of Blossom-end Rot in Relation to Water-soluble Ca Concentration in Tomato Fruits as Affected by Ca Nutrition under Root Restriction
kn-title=培養液中Ca濃度が根域制限栽培したトマト果実の 水溶性Ca濃度と尻腐れ果発生に及ぼす影響
en-subtitle=
kn-subtitle=
en-abstract=根域制限下におけるトマトの養分吸収を調査した結果，培養液中Caの多くは排液とともに排出され，Ｎに対するCaの吸収比率は園試処方やHoagland処方中の比率の50%以下であった．そこで，園試処方培養液中のCa(NO3)2･4H2Oの一部をNH4NO3に置換してCa濃度１，２，４ﾋの培養液を作成し，日射比例給液制御下で ‘ハウス桃太郎’の根城制限栽培（培地容量250，500
?）を行った．培養液のCa濃度が１ﾋであっても排液中のCa濃度が２ﾋよりも高く推移したが，Ca吸収量は極めて少なく，著しいCa欠乏症状が現れた．低Ca濃度区では尻腐れ果が多発し，１ﾋ区では第３果房より上段の果実は全て尻腐れ果となり，第９果房までの収量は２ﾋ区，１ﾋ区でそれぞれ４ﾋ区の50%，36%に低下した．腋芽茎中のCa濃度の低下は0.6N-NaCl可溶性画分や0.6N-HCl可溶性画分と比較して水溶性画分の低下が著しかった．そこで，Ca濃度が１〜４ﾋの培養液を用いて点滴栽培を行い，果実中のCa濃度を分画して定量した．果実頂部のCa濃度はいずれの画分においても培養液中Ca濃度が低いほど低く，開花から尻腐れ症状が発生するまでの日数も短くなった．尻腐れ果発生率と果頂部の水溶性Ca濃度との間にのみ有意な負の相関が認められた．以上のことから，果実の水溶性Ca濃度がトマトの尻腐れ果発生リスクの大小に大きくかかわっており，植物体の水溶性Ca濃度測定は尻腐れ果発生防止のためのCa栄養診断に応用できる可能性が高いと考えられる．
kn-abstract=The rate of absorbed Ca to N was less than half of Enshi or Hoagland solution in tomato (Solanum lycopersicum Mill.) grown with restricted root zone volume in previous experiments. Tomato plants were grown in plastic pots containing 250 or 500ml of peat based medium with modified Enshi solutions containing 1, 2 or 4mM of Ca. The solutions were prepared by replacing a part of Ca(NO3)2・4H2O to NH4NO3. Although Ca concentration was higher than 2mM in drainage collected from plants supplied 1mM Ca solution, absorbed amount of Ca was very small and severe symptom of Ca deficiency was observed. Incidence of blossom-end rot (BER) increased with decrease in Ca concentration of the solution and yield decreased to 50% and 36% of 4mM control, in 2mM and 1mM plots, respectively. Among fractionated Ca in stem of lateral shoot, decrease in water-soluble fraction was remarkable compared to 1N NaCl- or 0.6N HCl-soluble fractions. Tomato plants were then grown with modified solutions containing 1~4mM of Ca and fractionated Ca was determined for distal half of fruits. With decrease in solution Ca, fruit Ca decreased in all fractions, and days to BER incidence after flowering also decreased. Significant relationship was found only between the water-soluble Ca concentration in fruit tissue and rate of BER incidence. Thus water-soluble Ca in tomato fruit may closely relate to BER incidence, and an efficient tool to estimate the potential risk of BER may possibly be developed by determining the Ca fraction in the stem of lateral shoots.
en-copyright=
kn-copyright=

en-aut-name=YoshidaYuichi
en-aut-sei=Yoshida
en-aut-mei=Yuichi
kn-aut-name=吉田裕一
kn-aut-sei=吉田
kn-aut-mei=裕一
aut-affil-num=1
ORCID=

en-aut-name=ShingaiAya
en-aut-sei=Shingai
en-aut-mei=Aya
kn-aut-name=新開礼
kn-aut-sei=新開
kn-aut-mei=礼
aut-affil-num=2
ORCID=

en-aut-name=OoyamaMitsuo
en-aut-sei=Ooyama
en-aut-mei=Mitsuo
kn-aut-name=大山光男
kn-aut-sei=大山
kn-aut-mei=光男
aut-affil-num=3
ORCID=

en-aut-name=MurakamiKenji
en-aut-sei=Murakami
en-aut-mei=Kenji
kn-aut-name=村上賢治
kn-aut-sei=村上
kn-aut-mei=賢治
aut-affil-num=4
ORCID=

en-aut-name=GotoTanjuro
en-aut-sei=Goto
en-aut-mei=Tanjuro
kn-aut-name=後藤丹十郎
kn-aut-sei=後藤
kn-aut-mei=丹十郎
aut-affil-num=5
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=

affil-num=3
en-affil=
kn-affil=

affil-num=4
en-affil=
kn-affil=岡山大学

affil-num=5
en-affil=
kn-affil=岡山大学
en-keyword=BER
kn-keyword=BER
en-keyword=Ca absorption
kn-keyword=Ca absorption
en-keyword=Ca fractions
kn-keyword=Ca fractions
en-keyword=dripfertigation
kn-keyword=dripfertigation
en-keyword=Enshi solution
kn-keyword=Enshi solution
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120927
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=バスピン血中濃度はインスリン抵抗性と相関があり、日本人にはrs77060950によって規定される血中濃度高値群が存在する
kn-title=Serum Vaspin Concentrations Are Closely Related to Insulin Resistance, and rs77060950 at SERPINA12 Genetically Defines Distinct Group with Higher Serum Levels in Japanese Population
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=TeshigawaraSanae
en-aut-sei=Teshigawara
en-aut-mei=Sanae
kn-aut-name=勅使川原早苗
kn-aut-sei=勅使川原
kn-aut-mei=早苗
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=124
cd-vols=
no-issue=2
article-no=
start-page=105
end-page=110
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120801
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Preclinical evaluation of telomerase-specific oncolytic virotherapy for human bone and soft tissue sarcomas
kn-title=テロメラーゼ依存性腫瘍融解ウイルス療法の骨・軟部肉腫に対する前臨床的検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=骨・軟部肉腫は, 一部に治療抵抗性で予後の悪い症例が存在するため, 新たな治療法の確立が重要な課題である.　我々は, 5型アデノウイルスを基本骨格として, テロメラーゼ活性に依存して増殖する腫瘍融解ウイルス（OBP-301）や, coxsackie and adenovirus receptor（CAR）陰性の腫瘍細胞に感染するファイバー改変型ウイルス（OBP-405）を用い, 骨・軟部肉腫細胞に対する抗腫瘍効果を検討した.　
　14種類の骨・軟部肉腫細胞株に対してOBP-301の細胞障害活性を検討し, 12種類の細胞株でOBP-301に感受性を認めた.　また, OBP-301の細胞障害活性はCARの発現と相関していた.　さらに, テロメラーゼ活性の低い細胞に対しても, 5型アデノウイルスの複製に必須のE1Aによりテロメラーゼ活性の増強効果がおこり, 強い抗腫瘍活性を示すことを明らかにした.　次に, 骨肉腫脛骨同所性移植動物モデルを作成しOBP-301を投与したところ, OBP-301投与群では対象群と比べて有意に腫瘍増殖を抑制した.　最後に, OBP-301に感受性を認めなかったCAR陰性細胞株に対してOBP-405を用いて検討し, OBP-405が有効に作用することを確認した.　
　OBP-301やOBP-405を用いたウイルス療法は, 骨・軟部肉腫に対する新たな治療法となる可能性がある.　
en-copyright=
kn-copyright=

en-aut-name=SasakiTsuyoshi
en-aut-sei=Sasaki
en-aut-mei=Tsuyoshi
kn-aut-name=佐々木剛
kn-aut-sei=佐々木
kn-aut-mei=剛
aut-affil-num=1
ORCID=

en-aut-name=TazawaHiroshi
en-aut-sei=Tazawa
en-aut-mei=Hiroshi
kn-aut-name=田澤大
kn-aut-sei=田澤
kn-aut-mei=大
aut-affil-num=2
ORCID=

en-aut-name=HaseiJo
en-aut-sei=Hasei
en-aut-mei=Jo
kn-aut-name=長谷井嬢
kn-aut-sei=長谷井
kn-aut-mei=嬢
aut-affil-num=3
ORCID=

en-aut-name=KunisadaToshiyuki
en-aut-sei=Kunisada
en-aut-mei=Toshiyuki
kn-aut-name=国定俊之
kn-aut-sei=国定
kn-aut-mei=俊之
aut-affil-num=4
ORCID=

en-aut-name=YoshidaAki
en-aut-sei=Yoshida
en-aut-mei=Aki
kn-aut-name=吉田晶
kn-aut-sei=吉田
kn-aut-mei=晶
aut-affil-num=5
ORCID=

en-aut-name=HashimotoYuuri
en-aut-sei=Hashimoto
en-aut-mei=Yuuri
kn-aut-name=橋本悠里
kn-aut-sei=橋本
kn-aut-mei=悠里
aut-affil-num=6
ORCID=

en-aut-name=YanoShuya
en-aut-sei=Yano
en-aut-mei=Shuya
kn-aut-name=矢野修也
kn-aut-sei=矢野
kn-aut-mei=修也
aut-affil-num=7
ORCID=

en-aut-name=YoshidaRyosuke
en-aut-sei=Yoshida
en-aut-mei=Ryosuke
kn-aut-name=吉田亮介
kn-aut-sei=吉田
kn-aut-mei=亮介
aut-affil-num=8
ORCID=

en-aut-name=UnoFutoshi
en-aut-sei=Uno
en-aut-mei=Futoshi
kn-aut-name=宇野太
kn-aut-sei=宇野
kn-aut-mei=太
aut-affil-num=9
ORCID=

en-aut-name=KagawaShunsuke
en-aut-sei=Kagawa
en-aut-mei=Shunsuke
kn-aut-name=香川俊輔
kn-aut-sei=香川
kn-aut-mei=俊輔
aut-affil-num=10
ORCID=

en-aut-name=MorimotoYuki
en-aut-sei=Morimoto
en-aut-mei=Yuki
kn-aut-name=森本裕樹
kn-aut-sei=森本
kn-aut-mei=裕樹
aut-affil-num=11
ORCID=

en-aut-name=UrataYasuo
en-aut-sei=Urata
en-aut-mei=Yasuo
kn-aut-name=浦田泰生
kn-aut-sei=浦田
kn-aut-mei=泰生
aut-affil-num=12
ORCID=

en-aut-name=FujiwaraToshiyoshi
en-aut-sei=Fujiwara
en-aut-mei=Toshiyoshi
kn-aut-name=藤原俊義
kn-aut-sei=藤原
kn-aut-mei=俊義
aut-affil-num=13
ORCID=

en-aut-name=OzakiToshifumi
en-aut-sei=Ozaki
en-aut-mei=Toshifumi
kn-aut-name=尾�ｱ敏文
kn-aut-sei=尾�ｱ
kn-aut-mei=敏文
aut-affil-num=14
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学

affil-num=2
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学

affil-num=3
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学

affil-num=4
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学

affil-num=5
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学

affil-num=6
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学

affil-num=7
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学

affil-num=8
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学

affil-num=9
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学

affil-num=10
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学

affil-num=11
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学

affil-num=12
en-affil=
kn-affil=オンコリスバイオファーマ

affil-num=13
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学

affil-num=14
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学
en-keyword=アデノウイルス
kn-keyword=アデノウイルス
en-keyword=肉腫
kn-keyword=肉腫
en-keyword=ALT
kn-keyword=ALT
en-keyword=ヒトテロメラーゼ逆転写酵素
kn-keyword=ヒトテロメラーゼ逆転写酵素
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120323
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=難溶解性薬物シロスタゾールの経口吸収挙動におけるin vitro?in vivo相関に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=KamadaNaoki
en-aut-sei=Kamada
en-aut-mei=Naoki
kn-aut-name=鎌田直興
kn-aut-sei=鎌田
kn-aut-mei=直興
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120323
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=顎変形症患者の手術後の咀嚼機能評価に関する検討−主観的評価と客観的評価の相関性について−
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=OnoYuko
en-aut-sei=Ono
en-aut-mei=Yuko
kn-aut-name=尾野裕子
kn-aut-sei=尾野
kn-aut-mei=裕子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20111231
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=B型肝炎免疫グロブリンによる予防療法下であっても、肝移植術前の血清HBV DNAは術後HBV再感染に相関する
kn-title=Serum hepatitis B virus DNA before liver transplantation correlates with HBV reinfection rate even under successful low-dose hepatitis B immunoglobulin prophylaxis
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=YasunakaTetsuya
en-aut-sei=Yasunaka
en-aut-mei=Tetsuya
kn-aut-name=安中哲也
kn-aut-sei=安中
kn-aut-mei=哲也
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=113
cd-vols=
no-issue=1313
article-no=
start-page=44
end-page=50
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=200501
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=酸化物ガラスの塩基度と XPS による O1s 化学シフトの相関に関する考察
kn-title=Consideration on the Correlation between Basicity of Oxide Glasses and O1s Chemical Shift in XPS
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=O1s binding energy measured by X-ray photoelectron spectroscopy (XPS) is candidate as a new tool to determine a new scale of Lewis basicity of oxide ions in glass. Some mathematical expressions for the basicity or XPS chemical shift, such as charge parameter and optical basicity, were compared with the experimental O1s binding energy in binary alkali oxide glasses. The expressions so far in use needed some modification in parameters. A new empirical expression introduced in this paper gives a new concept and universal scale of basicity.
en-copyright=
kn-copyright=

en-aut-name=NanbaTokuro
en-aut-sei=Nanba
en-aut-mei=Tokuro
kn-aut-name=難波徳郎
kn-aut-sei=難波
kn-aut-mei=徳郎
aut-affil-num=1
ORCID=

en-aut-name=MiuraYoshinari
en-aut-sei=Miura
en-aut-mei=Yoshinari
kn-aut-name=三浦嘉也
kn-aut-sei=三浦
kn-aut-mei=嘉也
aut-affil-num=2
ORCID=

en-aut-name=SakidaShinichi
en-aut-sei=Sakida
en-aut-mei=Shinichi
kn-aut-name=崎田真一
kn-aut-sei=崎田
kn-aut-mei=真一
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Environmental Chemistry and Materials, Okayama University

affil-num=2
en-affil=
kn-affil=Department of Environmental Chemistry and Materials, Okayama University

affil-num=3
en-affil=
kn-affil=Health and Environment Center, Okayama University
en-keyword=XPS
kn-keyword=XPS
en-keyword=Basicity
kn-keyword=Basicity
en-keyword=Glass
kn-keyword=Glass
en-keyword=O1s binding energy
kn-keyword=O1s binding energy
en-keyword=Chemical shift
kn-keyword=Chemical shift
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20110325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=不動に関わる行動形質間の遺伝相関：不動のコストと進化力
kn-title=Genetic correlation between behavioral traits in relation to tonic immobility : cost and evolutionary force of tonic immobility
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=NakayamaSatoshi
en-aut-sei=Nakayama
en-aut-mei=Satoshi
kn-aut-name=中山慧
kn-aut-sei=中山
kn-aut-mei=慧
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=68
cd-vols=
no-issue=12
article-no=
start-page=2297
end-page=2300
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1956
dt-pub=19561231
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Study on the development of the sinus maxillaris in children by tomography Chapter III: Correlation between the development of the maxillary sinus of children and the shape of their face
kn-title=「レ」線断層撮影装置応用による小児上顎洞発育に関する研究 第三編 小児上顎洞発育度と顔型との相関関係に就いて
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The relation between the development of the paranasal sinus of school children and the shape of their face was studied. (1) The maxillary sinus area, ethmoidal sinus area and frontal sinus area have a high correlation with the up-down, left-right and anterior-posterior diameters, respectively. (2) The maxillary sinus area, and ethmoidal sinus area have a close correlation with the maximum head length, zygomatic arch width, external eye-orbit diameter, mandibular angle width, nasal height, morphological upper face height and morphological face height. However, the frontal sinus area has no correlation with them. (3) It is not clarified by my experiment, whether the mandible of pupils has any relation to the development of their paransal sinus.
en-copyright=
kn-copyright=

en-aut-name=NemotoEiki
en-aut-sei=Nemoto
en-aut-mei=Eiki
kn-aut-name=根本栄記
kn-aut-sei=根本
kn-aut-mei=栄記
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部耳鼻科教室
END

start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=6-2
article-no=
start-page=3591
end-page=3600
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1959
dt-pub=19590515
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Histological Studies on Correlation Between Function and Structure of Skeletal Muscle Part 3. Histological studies on correlation between function and structure of muscle spindle
kn-title=骨格筋の機能分化と構造との相関性に関する組織学的研究 第3編 筋紡錘の機能分化と構造との相関性に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1) By lipid and succinic dehydrogenase staining, it can be proved that muscle spindle (stretch receptor) consists of sarcosome rich (red) and sarcosome poor (pale) intrafusal fiber, which corresponds to the physiologically known 2 units, tonic (slow) and phasic (fast). 2) Muscle spindles can be classified into three types according to the histochemical type of intrafusal fibers. Type 1. Muscle spindle; consists of only red (tonic) intrafusal fibers Type 2. Muscle spindle; consists of only pale (phasic) intrafusal fibers Type 3. Muscle spindle; consists of both red and pale intrafusal fibers
Proximal muscles of the extremity with tonic function many 1 and 3 types while in the distal mucles with phasic contraction 2 and 3 types are often seen 3) Spindle efferent nerves (γ-fiber) consists of relatively large (5-9μ) and small (3-5μ) nerve fibers. 4) Human muscle spindle like that of a cat is composed of two types of intrafusal fibers and is innervated by small (6μ) and large (16μ) nerve fibers. These findings show that γ-system may exist in the human body as in a cat.
en-copyright=
kn-copyright=

en-aut-name=KondoMasami
en-aut-sei=Kondo
en-aut-mei=Masami
kn-aut-name=近藤正美
kn-aut-sei=近藤
kn-aut-mei=正美
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第1外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=6-2
article-no=
start-page=3569
end-page=3580
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1959
dt-pub=19590515
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Histological Studies on Correlation Between Function and Structure of Skeletal Muscle Part 1. Histological studies on correlation between function and structure of striated muscle fiber
kn-title=骨格筋の機能分化と構造との相関性に関する組織学的研究 第1編 骨格筋線維の機能分化と構造との相関性に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1) Every skeletal muscle contains three types of muscle fiber according to the content of sarcosome (mitochondria and fat body) in sarcoplasm which is the site of metabolism in the muscle fiber. In this study, these three types of fiber are classified as follows; sarcosome rich (red or dark), sarcosome poor (pale or light) and intermediate fiber. In general, sarcosome rich (red) fiber is thinner than the others, but that contained in functionally tonic proximal muscles of the extremity is thicker than the pale. The histological and histochemical differences among these three types of fibers are markedly seen in the lower animals than in the higher ones. 2) Extrinsic ocular muscles consist of three types of fiber with characteristic distribution. In the peripheral part of the muscle they are crowded with thin red fibers, but in the axial part the three types of fiber intermingle. 3) Red fibers in muscles with vigorous contractile power and also which take part in postural function have higher sarcosome density than the others. But muscles taking part in isotonic contraction and plastic tonus contain numerous intermediate fibers. Extremity muscles with phasic function have numerous sarcosome poor (pale) and a few intermediate and red fibers. Considering these findings, it seems that the three functions of the muscle are taken partial charge by the three types of fiber. That is, contractile tonus to sarcosome rich (red), phasic contraction to sarcosome poor (pale) and plastic tonus to intermediate fiber. 4) Each muscle fiber of these three types differs in their microscopic picture of contraction by indirect electrical stimulation to the muscle. Contraction knots are seen only in the red fibers and tetanizing picture in the pale ones. 5) Den?rvated muscle atrophy appears more early in the pale fibers than in the red.
en-copyright=
kn-copyright=

en-aut-name=KondoMasami
en-aut-sei=Kondo
en-aut-mei=Masami
kn-aut-name=近藤正美
kn-aut-sei=近藤
kn-aut-mei=正美
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第1外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=7-8
article-no=
start-page=843
end-page=852
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=19890831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Variations in blood cholinesterase activity level in termite control workers using chlorpyrifos
kn-title=クロルピリホス使用シロアリ防除作業者の血中コリンエステラーゼ活性値の変動について
en-subtitle=
kn-subtitle=
en-abstract=In order to clarify the effect of chlorpyrifos on workers using chlorpyrifos for termite control, changes in the cholinesterase activity in the blood of 6 workers was surveyed. Cholinesterase activity in the plasma and erythrocytes decreased in the busy season from May to September and recovered in the off season of January. The ratio of the lowest level of plasma cholinesterase activity from a worker in the busy season to the average activities of a worker examined several times in the off season, was examined in each workers. The ratio was under 50% in 6 workers using chlorpyrifos. The ratio of the mean cholinesterase activity in the erythrocytes of a worker in the busy season to that in the off season was examined, and was about 70% in 6 workers. A negative correlation between working time and increasing ratio of plasma cholinesterase was significant. A marked change in the subjective and objective symptoms of workers was not absent in busy season. Although some workers showed a decrease in the number of erythrocytes and leukocytes, and an increase in serum lipase activities, and abnormalities in the serum lipids. The data indicated that plasma cholinesterase activity levels are useful for biological exposure monitoring of chlorpyrifos.
kn-abstract=1986年9月よりシロアリ防除剤として広く使用されだしたクロルピリホス(有機リン系殺虫剤)のシロアリ防除作業者への健康影響を明らかにするために,シロアリ防除事業所の従業員8名について追跡調査を行い,以下の結果を得た. 1.処理作業従事者(6名)の毎月初めの平均血漿コリンエステラーゼ活性値は1987年4月までは正常範囲であったが,シロアリ防除シーズン(繁忙期)の5月より低下を始め, 6月〜9月は正常値の下限(0.6ΔpH)以下であった.その後閑散期には回復に向かい, 1988年1月にはシーズン前の水準に戻った.各作業者においては,シーズン中の最低値は,シーズン前の水準(1986年11月〜1987年4月の各人の平均値)の50%以下であり,うち2名は10%以下にまで低下した.一方,主として営業従事者の2名の血漿コリンエステラーゼ活性値はシーズン中にやや低下したものの正常値の範囲内であり,シーズン中の最低値もシーズン前の水準の60%以上であった. 2.赤血球コリンエステラーゼ活性値は, 1987年6月から1988年1月まで8名とも正常範囲であったが, 6〜9月は低く, 12月及び翌年の1月は高値であった.前者の期間における各人の平均値の後者の期間における各人の平均値に対する割合は, 8人の平均で72.2%であった. 3. 1作業者の観察において,シーズン中の処理作業従事時間数と血漿コリンエステラーゼ活性値の増加率との間には有意の負の相関が認められ, 1日の時間数が2時間で血漿コリンエステラーゼ活性値は横這い,それ以上で低下,それ以下で上昇することが明らかになった. 4.作業者の自覚症状,他覚症状には顕著な異常は認められていない.作業者によっでは赤血球数および白血球数の若干の低下,血清脂質およびリパーゼの異常等が認められており継続観察の必要がある. 5.血漿コリンエステラーゼ活性値はクロルピリホスの生物学的暴露指標として鋭敏であり,クロルピリホスによる健康障害の予防のために有用である.
en-copyright=
kn-copyright=

en-aut-name=JitsunariFumihiko
en-aut-sei=Jitsunari
en-aut-mei=Fumihiko
kn-aut-name=實成文彦
kn-aut-sei=實成
kn-aut-mei=文彦
aut-affil-num=1
ORCID=

en-aut-name=AsakawaFumiyuki
en-aut-sei=Asakawa
en-aut-mei=Fumiyuki
kn-aut-name=浅川冨美雪
kn-aut-sei=浅川
kn-aut-mei=冨美雪
aut-affil-num=2
ORCID=

en-aut-name=NakajimaTaichi
en-aut-sei=Nakajima
en-aut-mei=Taichi
kn-aut-name=中嶋泰知
kn-aut-sei=中嶋
kn-aut-mei=泰知
aut-affil-num=3
ORCID=

en-aut-name=ShimadaJunko
en-aut-sei=Shimada
en-aut-mei=Junko
kn-aut-name=島田潤子
kn-aut-sei=島田
kn-aut-mei=潤子
aut-affil-num=4
ORCID=

en-aut-name=OgataMasana
en-aut-sei=Ogata
en-aut-mei=Masana
kn-aut-name=緒方正名
kn-aut-sei=緒方
kn-aut-mei=正名
aut-affil-num=5
ORCID=

affil-num=1
en-affil=
kn-affil=香川医科大学人間環境医学講座

affil-num=2
en-affil=
kn-affil=香川医科大学人間環境医学講座

affil-num=3
en-affil=
kn-affil=香川医科大学人間環境医学講座

affil-num=4
en-affil=
kn-affil=前田病院

affil-num=5
en-affil=
kn-affil=岡山大学医学部公衆衛生学教室
en-keyword=クロルピリホス
kn-keyword=クロルピリホス
en-keyword=シロアリ防除作業者
kn-keyword=シロアリ防除作業者
en-keyword=有機リン中毒
kn-keyword=有機リン中毒
en-keyword=コリンエステラーゼ活性値
kn-keyword=コリンエステラーゼ活性値
en-keyword=生物学的暴露指標
kn-keyword=生物学的暴露指標
END

start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=3-4
article-no=
start-page=327
end-page=345
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198904
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Correlation of EEG analysis and Parkinsonism
kn-title=パーキンソニズムの頭皮上と深部脳波の相関分析
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Scalp and depth EEG were obtained during thalamotomy in 19 Parkinsonian patients, and a correlation analysis was performed to demonstrate additional information. 1) The decrease in mean frequency of alpha and increase in theta activity constituted a characteristic feature in Parkinsonism. The degree of these findings was closely related to the progression of the disease. 2) Simultaneous recordings in the thalamus and the scalp tended to show approximate spectral values in mild cases, but demonstrated some differences as the disease progressed. 3) Comparison of scalp and thalamic recordings revealed the existence of coincident and independent alpha activities in each area. 4) Cross-correlation analysis of the scalp EEG revealed that there were some progessive changes in phase relationships, including advance of activities from the front and delay of from the occiput with phase shifts over 90°. 5) Travelling waves were also found in the depth EEG, and the direction was from the thalamus to the cortex in some cases, but reversed in others. The phase shifts of alpha activities between the scalp and the thalamus were from 10° to 90°. From these values, the conduction velocity of the spreading alpha were from 2.4m/s to 21.6m/s.
en-copyright=
kn-copyright=

en-aut-name=TanigawaMasahiro
en-aut-sei=Tanigawa
en-aut-mei=Masahiro
kn-aut-name=谷川雅洋
kn-aut-sei=谷川
kn-aut-mei=雅洋
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部脳神経外科学教室
en-keyword=Parkinsonism
kn-keyword=Parkinsonism
en-keyword=Depth EEG
kn-keyword=Depth EEG
en-keyword=Alpha activity Correlation analysis
kn-keyword=Alpha activity Correlation analysis
en-keyword=Travelling wave
kn-keyword=Travelling wave
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2010
dt-pub=20100325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=膵管内乳頭粘液性腫瘍におけるK-ras変異の1種類への収束は手術適応と相関している
kn-title=Single-Pattern Convergence of K-ras Mutation Correlates With Surgical Indication of Intraductal Papillary Mucinous Neoplasms
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=MizunoOsamu
en-aut-sei=Mizuno
en-aut-mei=Osamu
kn-aut-name=水野修
kn-aut-sei=水野
kn-aut-mei=修
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=34
cd-vols=
no-issue=
article-no=
start-page=21
end-page=40
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1964
dt-pub=19641025
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Bed Rock and Wall Rock Alteration of the Uranium Deposits at the Togo Mine, Tottori Prefecture (1) Katamo and Asabatake Deposits
kn-title=鳥取県東郷鉱山ウラン鉱床の基盤岩ならびに母岩の変質 (1)方面･麻畑鉱床
en-subtitle=
kn-subtitle=
en-abstract=The Katamo and Asabatake Uranium Deposits, Togo Mine, about 5 Km south east of the lake Togo, central Tottori prefecture, is investigated to understand the nature of the bed rock and wall rock alterations. These alterations are remarkable and characterized as follows. (1) Both the clay mineral species and their relative amounts are closely related to the "oxidation-reduction enviroment" of the deposits. (2) The degree of alteration depends on the nature of the mother rocks and differs from an area to another. The most remarkable alteration is realized in the secondary oxidation zone. (3) Although the secondary uranium minerals are confined in the oxidation zone, there is no apparent relationship between the total amounts of clay minerals and uranium contents of the deposits. But the amounts of montmorillonite seems to decrease as uranium content goes up within some limited areas. The principal clay mineral in the deposits is montmorillonite. Kaolinite is also present in a small amount. Sericite is found only in some of the veins as an accessory mineral. Hydrothermal solutions seems to have played an important role for the formation of montmorillonite, as it is found in a well crystallized form in altered acidic pyroclastic sediments. Kaolinite, on the other hand, has a tendency to increase in its amount in arkose sediments which are sandwiched in volcanic sediments. This seems to show that kaolinite is a weathered product of the bed rocks of this region. The results presented in this paper could be a help in considering the origin of the Uranium deposits in this area.
kn-abstract=東郷鉱山,方面･麻畑ウラン鉱床の基盤岩および母岩は粘土化が著しく,その特徴として次のことが挙げられる. (a)粘土鉱物の種類,存在量は,鉱床の酸化帯･非酸化帯にはゞ規制されている.(b)粘土化の程度は原岩の種類により異なり,同一種数の岩石では酸化帯における変質が特に顕著である.(c)粘土量とウラン含有量との間には明確な相関は見出せないが,モンモリロナイトの量についてのみ観察すると,おおよそ負の相関がみられる.また,粘土化の主体をなすモンモリロナイトは,結晶度が良好で熱水変質が示唆きれる.化学分析の結果,SiO(2)の量が少ないので珪ばん比が異常に小さいが,ウラン鉱床近辺においてモンモリロナイト化に伴なう珪化帯が認められず,珪酸の逸脱が考えられる.鉱量的にみて,両鉱床の主体をなすウラン鉱物が燐顧塩鉱物であり,珪酸塩鉱物が少ないことなどから,モンモリロナイト化作用と鉱化作用との間には,直接関連がないものと考察される.
en-copyright=
kn-copyright=

en-aut-name=WatanabeKoji
en-aut-sei=Watanabe
en-aut-mei=Koji
kn-aut-name=渡辺晃二
kn-aut-sei=渡辺
kn-aut-mei=晃二
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学温泉研究所地質学部門
END

start-ver=1.4
cd-journal=joma
no-vol=55
cd-vols=
no-issue=
article-no=
start-page=7
end-page=10
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1984
dt-pub=19841130
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Spa therapy for patients with chronic obstructive lung disease
kn-title=Studies on the release of histamine from basophils 4. Difference between house dust- and Candida-induced secretion
en-subtitle=
kn-subtitle=
en-abstract=ハウスダストあるいはカンジダが特異抗原である気管支喘息30例を対象に,それぞれの抗原刺激時の好塩基球からのヒスタミン遊離を,抗ヒトIgEによる遊離と比較検討した. 1. ハウスダストが原因抗原である症例の好塩基球からのヒスタミン遊離は,抗原刺激時41.8%,抗ヒトIgE刺激時40.8%であった. 2. カンジダが原因抗原である症例の好塩基球からのヒスタミン遊離は,抗原刺激時27.1%,抗ヒトIgE刺激時32.2%であった. 3. ハウスダストと抗ヒトIgEによる好塩基球からのヒスタミン遊離は,ほぼ同様の値を示した. 一方カンジダと抗ヒトIgEによるヒスタミン遊離の間には有意の
相関関係はみられなかった.
kn-abstract=Histamine releasse from basophils induced by house dust and C. albicans was examined in 30 patients with bronchial asthma. House dust and C. albicans caused a significant amount of histamine release in subjects with a RAST score to corresponding allergen. A close correlation was found between house dust- and anti-IgE-induced histamine release. However, histamine release induced by C. albicans was considerably different from the release induced by anti-IgE.
en-copyright=
kn-copyright=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=1
ORCID=

en-aut-name=KomagoeHaruki
en-aut-sei=Komagoe
en-aut-mei=Haruki
kn-aut-name=駒越春樹
kn-aut-sei=駒越
kn-aut-mei=春樹
aut-affil-num=2
ORCID=

en-aut-name=SudoMichiyasu
en-aut-sei=Sudo
en-aut-mei=Michiyasu
kn-aut-name=周藤真康
kn-aut-sei=周藤
kn-aut-mei=真康
aut-affil-num=3
ORCID=

en-aut-name=MorinagaHiroshi
en-aut-sei=Morinaga
en-aut-mei=Hiroshi
kn-aut-name=森永寛
kn-aut-sei=森永
kn-aut-mei=寛
aut-affil-num=4
ORCID=

en-aut-name=KitaniHikaru
en-aut-sei=Kitani
en-aut-mei=Hikaru
kn-aut-name=貴谷光
kn-aut-sei=貴谷
kn-aut-mei=光
aut-affil-num=5
ORCID=

en-aut-name=NakagawaSaburo
en-aut-sei=Nakagawa
en-aut-mei=Saburo
kn-aut-name=中川三郎
kn-aut-sei=中川
kn-aut-mei=三郎
aut-affil-num=6
ORCID=

en-aut-name=KimuraIkuro
en-aut-sei=Kimura
en-aut-mei=Ikuro
kn-aut-name=木村郁郎
kn-aut-sei=木村
kn-aut-mei=郁郎
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=3
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学第2内科

affil-num=6
en-affil=
kn-affil=岡山大学第2内科

affil-num=7
en-affil=
kn-affil=岡山大学第2内科
END

start-ver=1.4
cd-journal=joma
no-vol=24
cd-vols=
no-issue=
article-no=
start-page=19
end-page=21
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2007
dt-pub=200712
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Study on the usefulness of Meg1Crb10 transgenic mouse as aType2 diabetes mellitus model animal. -Analysis of blood plasma component and expression of genes related to onset of diabetes -
kn-title=2型糖尿病モデル動物Meg1/Grb10遺伝子導入マウスの有用性の検討 - 血漿成分及び糖尿病関連遺伝子の発現と発症の解析 -
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Meg1/Grb10遺伝子導入マウス（Meg1マウス）はインスリンのシグナル伝達阻害による高インスリン血症を呈することから2型糖尿病モデルと考えられている。Meg1マウスは肥満を伴なわずに高血糖を発症するが､脂肪･カロリーの過剰摂取によっても糖尿病の発症が著しく増加する｡本研究はMeg1マウスの2型糖尿病モデルとしての有用性を検討するために､Meg1マウスと対照マウスを高脂肪･高カロリー飼料（HFD）及び対照飼料（NFD）で飼育した時の血漿アディポネクチン量とBMI値を比較するとともに糖尿病関連遺伝子の発現量について他の糖尿病モデルマウスと比較検討した。血漿アディポネクチン量はMeg1マウスのHFDが最も高く､対照マウスのNFDが最も低い値を示した。一方､BMI値は対照マウスのHFDが最も高い値を示し､血漿アディポネクチン量とBMI値は逆相関が認められ､ヒト2型糖尿病と類似することが認められた。また､Grb10､Glut4遺伝子の発現量はMeg1マウスと他の糖尿病モデルマウスでは異なる値を示し､Meg1マウスでのGrb10遺伝子の発現量は高く､Glut4遺伝子の発現量は低かった。以上のことから､Meg1マウスには他の糖尿病モデルと異なる発症機構の存在が示唆され､Meg1マウスは2型糖尿病モデルとしての有用性が考えられた。
en-copyright=
kn-copyright=

en-aut-name=YamamotoYoshie
en-aut-sei=Yamamoto
en-aut-mei=Yoshie
kn-aut-name=山本美江
kn-aut-sei=山本
kn-aut-mei=美江
aut-affil-num=1
ORCID=

en-aut-name=SuzukiOsamu
en-aut-sei=Suzuki
en-aut-mei=Osamu
kn-aut-name=鈴木治
kn-aut-sei=鈴木
kn-aut-mei=治
aut-affil-num=2
ORCID=

en-aut-name=Yamada-UchioKozue
en-aut-sei=Yamada-Uchio
en-aut-mei=Kozue
kn-aut-name=山田-内尾こずえ
kn-aut-sei=山田-内尾
kn-aut-mei=こずえ
aut-affil-num=3
ORCID=

en-aut-name=Ishino-KanekoTomoko
en-aut-sei=Ishino-Kaneko
en-aut-mei=Tomoko
kn-aut-name=石野-金児智子
kn-aut-sei=石野-金児
kn-aut-mei=智子
aut-affil-num=4
ORCID=

en-aut-name=MatsudaJunichirou
en-aut-sei=Matsuda
en-aut-mei=Junichirou
kn-aut-name=松田潤一郎
kn-aut-sei=松田
kn-aut-mei=潤一郎
aut-affil-num=5
ORCID=

en-aut-name=SatoKatsunori
en-aut-sei=Sato
en-aut-mei=Katsunori
kn-aut-name=佐藤勝紀
kn-aut-sei=佐藤
kn-aut-mei=勝紀
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院自然科学研究科

affil-num=2
en-affil=
kn-affil=医薬基盤研究所生物資源研究部

affil-num=3
en-affil=
kn-affil=医薬基盤研究所生物資源研究部

affil-num=4
en-affil=
kn-affil=東海大学健康科学部

affil-num=5
en-affil=
kn-affil=医薬基盤研究所生物資源研究部

affil-num=6
en-affil=
kn-affil=岡山大学大学院自然科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=143
cd-vols=
no-issue=
article-no=
start-page=27
end-page=38
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2010
dt-pub=20100225
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A Sturdy on a Method of Guidance Developing Basic Abilities of Choral Singing I
kn-title=合唱の基礎能力を伸ばす指導法に関する研究�T
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=合唱指導における呼吸法指導の重要性をKenneth. H. Phillips著『Teaching Kids To Sing』に沿って考察した｡その結果,呼吸法と発声および姿勢と発声の相関性,幼少期からの継続的な呼吸法の練習や姿勢の捉え方の正しい認識などの重要性を再確認することができた｡特徴としては,｢姿勢の発達練習｣に際して,胴体の伸張,肩･腕の準備運動,首･頭の準備
運動,脚の準備運動という流れを基本としている｡さらに,｢活動的な姿勢のとり方｣と｢精神的な姿勢のとり方｣では,開放的な空間をイメージして発声する点,フレーズの動きと腕の動作を利用する点など,エネルギーと音楽の方向が一体となっていること,アレクサンダー･テクニークをとりいれた精神的な開放と身体のリラックスに重点が置かれていることがわかった｡
en-copyright=
kn-copyright=

en-aut-name=MushiakiMasako
en-aut-sei=Mushiaki
en-aut-mei=Masako
kn-aut-name=虫明眞砂子
kn-aut-sei=虫明
kn-aut-mei=眞砂子
aut-affil-num=1
ORCID=

en-aut-name=KuroiKaori
en-aut-sei=Kuroi
en-aut-mei=Kaori
kn-aut-name=黒井かおり
kn-aut-sei=黒井
kn-aut-mei=かおり
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=元新見市立井倉小学校
en-keyword=合唱
kn-keyword=合唱
en-keyword=ウォーミング・アップ
kn-keyword=ウォーミング・アップ
en-keyword=姿勢
kn-keyword=姿勢
en-keyword=呼吸法
kn-keyword=呼吸法
en-keyword=指導
kn-keyword=指導
END

start-ver=1.4
cd-journal=joma
no-vol=38
cd-vols=
no-issue=5
article-no=
start-page=211
end-page=214
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=19890505
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Extractability of ion-associates fromed between organic onium ions and tetrabromophenolphthalein ethyl ester anion into a mixed micelle
kn-title=有機オニウムイオン-テトラブロモフェノールフタレインエチルエステル陰イオンのイオン会合体のミセル抽出
en-subtitle=
kn-subtitle=
en-abstract=Tetrabromophenolphthalein ethyl ester (TBPE?H) forms the mixed micelle (TBPE?H + nTX-100)(m) with Triton X-100 (TX-100) at pH 4. If a hydrophobic organic onium ion (C(+)) exists together, it forms an ion associate (C(+)?TBPE(-)), and dissolves into the micelle (micelle extraction of ion associates). The equilibrium of micelle extraction is expressed as follows, (TBPE?H + nTX-100)(m) + C(+) ? (C(+)?TBPE + nTX-100)(m) + H +(n≒10). In this work, the equilibrium of the micelle extraction of several organic onium ions, such as amines, ammonium ions, phoshonium ions, arsonium ion with various alkyl and/or aryl groups were investigated. The extractability of ion-associates into the micelle showed a good correlation with the extractability of ion associates into chloroform.
kn-abstract=テトラブロモフェノールフタレインエチルエステル(TBPE・H)はpH4でTritonX-100(TX-100)と混合ミセル(TBPE・H+nTX-100)(m)を形成している.これに,疎水性の有機オニウムイオン(C(+))が加えられると(C(+)・TBPE(-))のイオン会合体が生成され,ミセルに可溶化する(イオン会合体のミセル抽出).ミセル抽出の平衡は式,(TBPE・H+nTX-100)(m)+C(+)?(C(+)・TBPE(-)+nTX-100)(m)+H(+),(n≒10)に従うものとし,各種アルキル基を持つアミン,アンモニウムイオン,ホスホニウムイオン,アルソニウムイオンなどのオニウムイオンについて,ミセル抽出平衡を検討した.オニウムイオンのミセル抽出性は水-クロロホルム系における抽出性と良い相関を示すことが分かった.
en-copyright=
kn-copyright=

en-aut-name=HosoiYasuhiro
en-aut-sei=Hosoi
en-aut-mei=Yasuhiro
kn-aut-name=細井康宏
kn-aut-sei=細井
kn-aut-mei=康宏
aut-affil-num=1
ORCID=

en-aut-name=MotomizuShoji
en-aut-sei=Motomizu
en-aut-mei=Shoji
kn-aut-name=本水昌二
kn-aut-sei=本水
kn-aut-mei=昌二
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=micelle extraction of ion associates
kn-keyword=micelle extraction of ion associates
en-keyword=ion associates of organic onium ions with tetrabromophenolphthalein ethyl ester
kn-keyword=ion associates of organic onium ions with tetrabromophenolphthalein ethyl ester
en-keyword=equilibrium constants of micelle extraction of ion associates
kn-keyword=equilibrium constants of micelle extraction of ion associates
en-keyword=non-ionic surfactant Triton X-100
kn-keyword=non-ionic surfactant Triton X-100
END

start-ver=1.4
cd-journal=joma
no-vol=99
cd-vols=
no-issue=1
article-no=
start-page=35
end-page=42
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2010
dt-pub=20100201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=休眠程度の異なるブドウ‘ピオーネ’の発芽に及ぼす温度の影響
kn-title=Effect of Temperature on 'Pione' Grapevine Budbreaking at Different Stages of Dormancy
en-subtitle=
kn-subtitle=
en-abstract=露地栽培されているブドウ‘ピオーネ’について，休眠の深さが異なる7月から翌年3月まで約1か月間隔で枝を採取し，1芽を有す挿し穂を調整した後，20，25および30℃に制御したインキュベーター（いずれも14時間日長）に入れ，経時的に発芽を調査した．発芽の早さを示す発芽所要日数と発芽の揃いを示す60%発芽所要日数から発芽に及ぼす温度の影響を評価した．実験期間中の温度を測定し，休眠完了と温度との関係を考察した．いずれの処理時期においても30℃の発芽が最も優れ，次いで25℃，20℃の順であった．しかし，発芽に及ぼす温度の影響は処理時期によって大きく異なった．すなわち，発芽所要日数は7月から10月までは徐々に増加し，11月に最大に達した後，3月に向けて少しずつ減少した．このことから，‘ピオーネ’では7月から9月が条件的休眠期，10月から12月が自発休眠期，1月から3月が他発休眠期と推察された．自発休眠期までの最終発芽率はいずれの温度も100%未満であり，また7月〜9月の20℃処理では60%未満の発芽率であった．一方，自発休眠期の中期以降の処理ではいずれの温度とも均一な発芽を示し，最終発芽率はほぼ100%であった．11月以降の処理において，発芽所要日数と7.2℃以下の温度に遭遇した時間数（CCH）との間に有意な負の相関があった．また，11月１日から各処理時期までの0℃以上の温度に遭遇した時間数と20，25または30℃で処理を始めた日から各処理区の発芽までの時間数との積算（CT, ℃・h）との間にも有意な負の相関が認められた．以上のことから，‘ピオーネ’の芽の休眠完了の予測には低温遭遇量だけでなく，0℃以上の積算温度による方法も有効と考えられた．
kn-abstract=The effects of temperature on budbreak of cuttings obtained at different stages of dormancy from 'Pione' grapevines (Vitis labrusca × V. vinifera) grown in open field were investigated. Cuttings were collected at monthly intervals from July to March. Judging from the number of days to initial and 60% budbreak after treatment, indicating promotion and the uniformity of budbreak, respectively, 30℃ was the most effective in budbreak, followed by 25 and 20℃ in that order in all treatment times. However, the effect of temperature on budbreak was markedly affected by treatment time. The number of days to initial budbreak (NDIB) increased gradually from July to October, peaked in December and thereafter decreased gradually towards March. The periods from July to September, from October to December, and from January to March were assumed to correspond to paradormancy, endodormancy, and ecodormancy of 'Pione' grapevines, respectively. Final percentage of budbreak was less than 100% until endodormancy for all temperatures. It was below 60% at 20℃ treatments of July to September. On the other hand, a uniform budbreak was observed in the treatments after the middle of endodormancy for all temperatures, resulting in almost 100% of final percentage of budbreak. There was a significant negative correlation between NDIB and cumulative chilling hour (CCH) of exposure to below 7.2℃ in the treatments after November, and also between NDIB and cumulative temperature (CT, ℃･h), a summation of temperature and hours of exposure to above 0°C from November 1 to each treatment time and hours of exposure to 20, 25, or 30℃ from start of treatment
to budbreak in each plot. The results suggest that besides CCH, CT can also be used to estimate the completion of dormancy in 'Pione' grapevine bud.
en-copyright=
kn-copyright=

en-aut-name=PotjanapimonChaiwat
en-aut-sei=Potjanapimon
en-aut-mei=Chaiwat
kn-aut-name=ポジャナピモンチャイワット
kn-aut-sei=ポジャナピモン
kn-aut-mei=チャイワット
aut-affil-num=1
ORCID=

en-aut-name=FukudaFumio
en-aut-sei=Fukuda
en-aut-mei=Fumio
kn-aut-name=福田文夫
kn-aut-sei=福田
kn-aut-mei=文夫
aut-affil-num=2
ORCID=

en-aut-name=KubotaNaohiro
en-aut-sei=Kubota
en-aut-mei=Naohiro
kn-aut-name=久保田尚浩
kn-aut-sei=久保田
kn-aut-mei=尚浩
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学
en-keyword=breaking of grapevine bud
kn-keyword=breaking of grapevine bud
en-keyword=cumulative chilling hour (CCH)
kn-keyword=cumulative chilling hour (CCH)
en-keyword=cumulative temperature (CT)
kn-keyword=cumulative temperature (CT)
en-keyword=different dormant stages
kn-keyword=different dormant stages
en-keyword=temperature
kn-keyword=temperature
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=17
end-page=21
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The simplified method of measuring Radon in mineral waters by the liquid scintillation counter.
kn-title=液体シンチレーション計数器を用いるRn-222の簡易定量法
en-subtitle=
kn-subtitle=
en-abstract=Radon in mineral waters was determined with simplicity by newly developed method. In this method, 2.0m? of water sample was directly mixed with 15 m? of Hionic-Fluor in a vial, which was then filled up with additional Hionic-Fluor ; 190 minutes were allowed for the radioactivity to equilibrate. The radioactiviity of Radon was measured by the Liquid Scintillation Counter (Tri-Carb 460C). Radon content was easily calculated with the proposed formula by an electric desk calculater. The reproducibility was proved CV=5.77 % ; the lowest detection limit was 0.2 nCi/l. An adequate correlation was obtained from the results of measurements compared with the original method ; r=0.996, y=0.818x×0.875.
kn-abstract=鉱泉水中のラドンを測定するため，抽出法を省略し，少量の試料水を直接液状シンチレーターに溶解し，液体シンチレーション計数器を用いて放射能を測定し，次いで簡単な計算法により試料水中のラドン濃度を計算する簡易定量法を試みた。本法を用いて一鉱泉水のラドンを反復測定した際の精度は，σ＝0.136nCi/l，CV＝5.77　％　，（x＝2.36n　Ci/l）であった。次に本法でのRnの最少検出量は，0.2nCi/lである。原法と本法とを用いて得られた測定値の間には，r＝0.996，y＝0.818x＋0.875なる相関関係が成立した。本法を使用すると，簡単な予備処理後，極短時間内にラドンの測定が可能なため，花崗岩地域の井水，鉱泉水中のラドンを定量するためには，有用な方法である。
en-copyright=
kn-copyright=

en-aut-name=MifuneMasaaki
en-aut-sei=Mifune
en-aut-mei=Masaaki
kn-aut-name=御舩政明
kn-aut-sei=御舩
kn-aut-mei=政明
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院中央検査部
en-keyword=鉱泉水 (Mineral waters)
kn-keyword=鉱泉水 (Mineral waters)
en-keyword=ラドン (Radon)
kn-keyword=ラドン (Radon)
en-keyword=放射能泉 (Radioactive springs)
kn-keyword=放射能泉 (Radioactive springs)
en-keyword=液体シンチレーション計数器 (Liquid scintillation counter)
kn-keyword=液体シンチレーション計数器 (Liquid scintillation counter)
END

start-ver=1.4
cd-journal=joma
no-vol=70
cd-vols=
no-issue=12
article-no=
start-page=4593
end-page=4602
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1958
dt-pub=19581231
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the Capillary Picture at the Root of the Nail in Ifeectious Hepatitis Part 2 Studies on the correlativity between the capillary picture at the root of the nail and the results of the clinical examinations
kn-title=流行性肝炎患者の指爪根部毛細血管像に関する研究 第二編 指爪根部毛細血管像と各種臨床検査成績との相関性について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The capillary picture at the root of the nail was observed, comparing it with the results of the various clinical examinations, on 60 cases of hepatitis in our hospital and the correlativity between them was studies. The results are as follows. 1. The correlation between hepatomegaly and the capillary reaction is observed. 2. The correlation between splenomegaly or enlargement of the splenic dulness and the capillary reaction is observed. 3. The severe capillary reaction is observed in the cases with the decrease of hemoglobin in volume and erythrocyte in number, and also in the cases with the decrease of leucocyte in number and the remarkable increase of monocvte. 4. The correlation between the capillary reaction and the liver functions, i.d. urobilinogen and bilirubin in urine, bilirubin in serum jaundice and also the serum colloidal reaction, excretory process of foreign bodies antidotal function. The severe capillary reaction is also observed in the cases with the decreased ratio of albumin/globulin. 5. The special correlation between the sedimentation rate and the capillary reaction is not observed. 6. The correlation between the hemorrhagic tendency and the capillary reaction is not observed, but the correlation is observed in the cases with a hemorrhage on the capillary picture. 7. The opposite attitude is observed between the cases with the star-form capillary dilatation in the body surface and the capillary reaction at the root of the nail. 8. The capillary reaction has relation to the biopsy findings of the liver, especially the parenchymal damage of the liver, but no relation to the change of the Glisson's capsule. However, no differences of the capillary reaction are observed between the cases with the parenchymal and stromal change. 9. The disorder of the autonomic nervous system is greatly observed in the cases of chronic hepatitis with the normal liver function, but with the capillary reaction. 10. The capillary picture at the root of the nail is expected to achieve the important roles on making the diagnosis, observing the course and judging the prognosis of hepatitis, since it finely agrees with the results of the various clinical examinations.
en-copyright=
kn-copyright=

en-aut-name=YoriyaTsuneo
en-aut-sei=Yoriya
en-aut-mei=Tsuneo
kn-aut-name=庵谷恒夫
kn-aut-sei=庵谷
kn-aut-mei=恒夫
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一内科教室
END

start-ver=1.4
cd-journal=joma
no-vol=73
cd-vols=
no-issue=10-12
article-no=
start-page=791
end-page=802
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1961
dt-pub=19611230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Electrophysiological Studies on Stereotaxic Surgery of Extrapyramidal Disorders Part 1. Surgical Lesions and Excitability of Spinal Motoneurons
kn-title=不随意運動症に対する定位脳手術に関する電気生理学的研究 第1編 定位脳手術侵襲点と脊髄運動ニユーロンの興奮性との相関に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1) An attempt was made to analyse the pre- and postoperative EMG in order to correlate the physiological mechanism of pyramidal and extrapyramidal systems with clinical symptoms in course of stereotaxic surgery. 2) Globus pallidus, thalamocapsular area and ventrolateral nuclei of thalamus were selected as the main anatomical locations for target. 3) The thalamocapsular lesion manifesting the shortening of the silent period of the H-wave recovery curve signifies the increased activity of the α -system and a symptom of pyramidal system disorders. 4) The prolongation of the period in the cases of pallidal and VL lesions represents the decrement of α-motoneuron excitability secondary to the functional drop of γ-system. 5) It seems to be clear the silent period shortening the lesions are involved in internal capsule and the prolonging ones are in the nuclei of the extrapyramidal system.
en-copyright=
kn-copyright=

en-aut-name=AdachiIwao
en-aut-sei=Adachi
en-aut-mei=Iwao
kn-aut-name=芦立巌
kn-aut-sei=芦立
kn-aut-mei=巌
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第1外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=75
cd-vols=
no-issue=10
article-no=
start-page=965
end-page=979
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1963
dt-pub=19631030
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Relations between Reticulo-endothelial System, Tumor and X-Rays
kn-title=網内系機能と悪性腫瘍並びに放射線との関係に就いて 第2編 実験腫瘍（吉田肉腫），網内系，放射線との相関に就いて
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Vol. �T The effect given to the blood picture and the function of the reticulo-endothelial system using reticulo-endothelial system blocked by the Indian ink method and also the tumor growth, survival rates and metastasis after transplanting Yoshida sarcoma cells intramusclarlly in the albino-rat thigh were examined. Experiment was done to find out the relations between the reticulo-endothelial system and the latter, which the results were as follows: 1) As formerly reported, the reticulo-endothelial system blocked by the Indian ink method showed anaemia by a certain quantity of ink but it passed by and restored gradually. It showed parallel relation with the function of the reticulo-endothelial system. 2) If the ink was small in quantity, it did not give much effects to tumor growth though the function of the reticulo-endothelial system was low. 3) The reticulo-endothelial system blocked by the Indian ink method had a connection with the growth of tumor to some extent and gave pictures which accelerated its growth. And stromal reaction near the tumor was weak. 4) Using the reticulo-endothelial system blocked by the Indian ink method, the appearance of the reticulo-endothelial cells in the tumor tissue was less compared with the control. Vol. �U Chapter 1 To prove the reaction on the X-rays of the reticulo-endothelial system and tumor growths, the author made an experiment based on the idea of tumor-host relationship. X-rays, 600r a day continuing 5 days totalling 3000r, were irradiated into the tumor bed, albino-rat thigh, and then Yoshida sarcoma cells were transplanted on the irradiated part. The influence against tumor growth, survival rates and metastasis were examined and the effects were found as follows: 1) Compared with the control, the tumor growths were restrained in the order of transplanted groups of the next day after irradiation, transplanted groups of 10 days after irradiation, and transplanted groups of 30 days after irradiation. With the survival rates, life extension could be recognized in the same order. 2) Stromal reaction could be strongly found in pre-irradiated groups, especially in these being transplanted the next day. Reticulo-endothelial cells could be found many compared with the control. Above all, it could be presumed that in case of preoperative irradiation, the part of reticulo-endothelial cells which has not been infiltrated by tumor cells shows protection system by stromal reaction. Chapter 2 When the tumor which was transplanted by Yoshida sarcoma cells became a regular induration; the size, the rise and fall, and the survival rates were examined by irradiating 300r a day for 10 days totalling 3000r. The effect showed that when the function of the reticulo-endothelial system which is one of the living body reaction was irradiated after it was restrained, the irradiation effect was less than the non-treated group. Consequently if the function of the reticulo-endothelial system would be irradiated after it was accelerated, it would obtain satisfactory result to medical treatments.
en-copyright=
kn-copyright=

en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邊正忠
kn-aut-sei=田邊
kn-aut-mei=正忠
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線医学教室
END

start-ver=1.4
cd-journal=joma
no-vol=75
cd-vols=
no-issue=7-9
article-no=
start-page=633
end-page=644
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1963
dt-pub=19630930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Study on Anticancer Chemotherapy Especially on the effect of anticancer agents and anticancer supporting substances on the metabolism of cancer bearing mice- PART �V The effect of anticancer agents and their supporting substances on serum protein metabolism in the hosts of malignant tumor and also on serum electrolytes
kn-title=癌の化学療法に関する研究 特に制癌剤並びに制癌強化剤の担癌生体内代謝に及ぼす影響に就いて 第3編 制癌剤および制癌強化剤の担癌生体血清蛋白代謝に及ぼす影響,並びに血清電解質代謝との相関に就いて
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Metabolisms of serum protein and electrolytes in cancer bearing mice were studied to correlate with the effect of anticancer agents and their supporting substances administration. The results obtained are as follows: 1) Serum albumin was decreased in course of cancer progress, which was in negative correlation with ascites increment. 2) Serum Ca tended to decrease, K to increase and Na to fluctuate erratically. 3) The combined administration of anticancer agents and their supportiog substances improved more the liver function to accelerate the assimilation of serum protein and the anticancer resistance, and also improved more serum Ca metabolism than single administration of the anticancer agents in cancer bearing mice.
en-copyright=
kn-copyright=

en-aut-name=MatsuuraUmeharu
en-aut-sei=Matsuura
en-aut-mei=Umeharu
kn-aut-name=松浦梅春
kn-aut-sei=松浦
kn-aut-mei=梅春
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部砂田外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=75
cd-vols=
no-issue=7-9
article-no=
start-page=617
end-page=632
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1963
dt-pub=19630930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Study on Anticancer Chemotherapy Especially on the effect of anticancer agents and anticancer supporting substances on the metabolism of cancer bearing mice PART �U The effect of anticancer agents and their supporting substances on nucleic acid metabolism of malignant tumor and on cancer cell proliferation
kn-title=癌の化学療法に関する研究 特に制癌剤並びに制癌強化剤の担癌生体内代謝に及ぼす影響について 第2編 制癌剤および制癌強化剤の担癌生体核酸代謝に及ぼす影響,並びに癌細胞分裂像との相関に就いて
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Nucleic acid metabolism of tumor itself and liver in cancer bearing mice, DNA matabolism of intraperitoneal free cancer cells were measured by microspectrophotometer (MSP) and their correlation with cancer cell proliferation were analyzed under administrations of anticancer agents and their supporting substances. The results obtained are as follows: 1) The ratio of RNA to DNA is approximately 2.6 in liver of normal mice. DNA was considerably increased in cancer bearing group, and was about 2.5 times greater than that of normal group. 2) Mitomycin inhibited DNA metabolism of tumor, also inhibited DNA assimilation in liver of tumor bearing mice. Anticancer supporting substances, esfecially orotic acid, in contrast, could hardly cause any change in DNA metabolism of tumor, but slightly increased RNA metabolism. 3) With regard to nucleic acid metabolism in cancer cells, DNA inhibited cell counts were increased and octoploid cell counts were decreased in case of mitomycin administration. On the other hand, three peak type of cellular arrangement was obtained in case of the administration of supporting substances, showing disturbance of DNA assimilation process. 4) Mitomycin caused disturbance of cell proliferation in early stage of administration course, and also abnormal proliferation and cell destruction. The supporting substances, on the other hand, did not cause any disturbance in process of normal proliferation but accelerated the original degeneration process of tumor eclls as if to drive tumor cells to the final stage of necrosis.
en-copyright=
kn-copyright=

en-aut-name=MatsuuraUmeharu
en-aut-sei=Matsuura
en-aut-mei=Umeharu
kn-aut-name=松浦梅春
kn-aut-sei=松浦
kn-aut-mei=梅春
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部砂田外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=77
cd-vols=
no-issue=5-6
article-no=
start-page=773
end-page=794
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1965
dt-pub=19650630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A Case of Camplete Retrograde Amnesia
kn-title=軽度の一酸化炭素中毒の既往歴を有し，脳器質性異常を基盤にして発生した全生活史健忘の興味ある一症例について―とくに意識障害との関連を中心とした全生活史健忘の文献的考察―
en-subtitle=
kn-subtitle=
en-abstract=A high school sophomore was brought to out-patient clinic shortly after she was found vagrant in a far-off city. She was admitted to our university hospital for complete psychiatric and neurological examinations. Her hospital course are briefed as follows. 1. The peychiatric exam disclosed the evidence that she had been anxiety stricken due to some mental conflicts for a long period of time. 2. A day prior to the onset of her amnestic episode she accidentally incurred carbon monoxide poisoning. 3. It was revealed later on a hospital day that when she happened to have been caught by a strange character on her way home in the evening she collapsed losing consciousness due to terror. 4. On a later day after the admission she spontaneously fell into a trance-like state and then began relating her lost memory retrogressively up to the point of the gas poising. When awoke, she was incidentally cured of the amnesia. 5. From then on she succumbed to serial headache attacks and fits resembling epleptic automatism, probably due to the fact that she became devoid of an important defense mechanism of "amnesia". However, these symptoms gradually simmmered down responding psychotherapeutic measures. The pathological findings on certain tests and examinations are described below. 1. Pneumoencephalogram revealed impressio digitatae, and some symmetrical enlargement of lateral and third ventricles. Spinal puncture showed pressure of 200mm H(2)O in the lateral recumbent position. 2. Electroencepharogram at rest showed the irregular basic activity consisting of 3-Sc/s slow wave bursts and sporadic sharp or spiky waves, which are dominant symmetrically in temporal, parietal and occipital regions, No activated patterns or evoked seizures were elicited by means of various sleep provacations. Neverthless, her emotional tension built up abnormal E. E. G. patterns; 6c/s positive spike waves were evoked intermittently. 3. Rorschach test indicated high score of anxiety, neurotic signs, signs of an epileptoid and severe loss of reality testing. The repeated Rorshach showed increased signs of epileptoid after the recovery of her amnesia. The clinical courses above stated and the survey of correlating literatures suggest tbat CO-poisoning worked just as a trigger to produse the amnesia on this case. Aside from the questions whether the fainting spell at the time of the assault was "epilepsy" itself or it merely triggered her off to an epileptic attack as a precipitating factor, it is surmised that the pathological neurological findings have an important relevance to her whole clinical course and prognosis. Organicity of the brain and resultant clouding of consciousness can ferment a dissociative reaction of complete retrograde amnesia.
kn-abstract=16才女子高校生にみられた約2ヵ月間にわたる全生活史健忘例の発端および経過として,1.長期間に準備された不安・葛藤状態があり 2.健忘発端の一日前に偶発的な一酸化炭素中毒に罹患し 3.ついで驚愕体験にひき続く意識障碍より覚醒した時に全生活史健忘が始まり, 4.自発性催眠様状態で過去の生活を継時的に追体験し遂に一酸化炭素に罹る直前の状態で覚醒し健忘の回復をみたが, 5.健忘回復後もなお情緒の動揺に関連し,癲癇自動症を疑わせる発作および頭痛が頻発し,これらは精神療法により情緒の安定が得られるまで持続した.検査所見としては1.一酸化炭素中毒以前より存在したと思われる脳室拡大,頭蓋骨指圧痕,髄液圧亢進が認められ, 2.発端となつた意識障碍とも或程度の関係が推定され,その後の自動症と発作の相関は確実と思われる脳波異常として,後頭側頭部優位の同期性,間歇性のirregular slow wave burstおよび散発性のsharp waveないしはspiky waveが全径過を通じ安静時記録で認められたが睡眠誘発で賦活されず,情緒動揺の著明な時期に一致して上記所見が増強し,とくに右側々頭部で6c/s positive spikeが繰り返し出現するのが確められ, 3.ロールシャッハテストでも不安・神経症徴候および重篤な現実との接触喪失徴候とならんで,癲癇徴候がことに健忘回復後に増強するのが認められた.以上の経過,所見により,本例において健忘の発端となつた意識障碍に対する一酸化炭素および癲癇(とくに情動により誘発される癲癇)の関与如何につき,文献的に比較検討,綜合的に考察し,一酸化炭素の関与は完全には否定し難いが比較的に少く,ごく軽度の意識水準低下として発生準備状態の一要素を形成はていたと推定されるにとどまり,一方癲癇の関与は,発端の意識障宮が情動により誘発された癲癇それ自身であつたか,原始反応としての意識障害を惹起する準備状態の器質的主要因であつたかは別として,相当大きな比重をもつものと推定されることを述べ,併せて全生活史健忘というヒステリー反応が器質的意識障害の機構を利用しても起り得ることを推論した.
en-copyright=
kn-copyright=

en-aut-name=KomotoJunko
en-aut-sei=Komoto
en-aut-mei=Junko
kn-aut-name=古元順子
kn-aut-sei=古元
kn-aut-mei=順子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部神経精神医学教室
END

start-ver=1.4
cd-journal=joma
no-vol=77
cd-vols=
no-issue=4
article-no=
start-page=711
end-page=716
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1965
dt-pub=19650430
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Corticoid Metabolism in the Body: Correlation Pattern of Blood and Urine Corticoids in Psychiatric Patients
kn-title=ステロイドの体内代謝:精神病者における尿・血中コルチコイド相関
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=To investigate the corticoid metabolism In Vivo of endogenous psychosis, authors have studied the relationship between urinary and serum corticoid patterns. Twenty four hour urine and blood samples were taken from 17 cases of both sexes of schizophrenic patients, 17 cases from both sexes of depressed patients, 17 cases from both sexes of normal control persons, 11 cases of right and left lobotomized chronic schizophsenic patients and 12 cases from both sexes of patients with pituitary tumors, pituitary cysts, craniopharyngeomas, disturbances in hypothalamus and so on. The urinary 17-KS were measured by a modified method of Koch and Holtorff and 17-OHCS were measured by Silber-Porter and Bongiovanni. Bacterial β Glucuronidase was used in hydrolysis. The results were as follows: 1. Free 17-OHCS in the urine and the serum were increased in schizophrenic and depressed patients in aggravating situations without exception. 2. Urinary 17-KS were decreased in aggravating situations in both schizophrenic and depressed patients. 3. The decrease of urinary 17-KS was significant in the male but not in the female. 4. High serum 17-CHCS levels were followed by high urine 17-OHCS values; in other words the values moved parallel in psychotic patients. 5. The value of conjugated 17-OHCS over free 17-OHCS (C/F) in the urine and blood always decreased in schizophrenic and depressed patients. 6. The ratios of urinary 17-KS over free serum 17-OHCS, and urinary total 17-OHCS over free serum 17-OHCS showed significant relationships in both schizophrenic and depressed patients; these ratios are decreased in an aghravating situation. 7. The frontal lobe plays a role in urinary 17-KS excretion. It should be emphasized that separating the frontal lobe from the thalamus or hypothalamus area will cause an increase in urinary 17-KS excretion. 8. Urinary or serum 17-OHCS values du not move in parallel to urinary 17-KS but rather in a reverse manner in psychotic patients.
en-copyright=
kn-copyright=

en-aut-name=KohsakaMutsutoshi
en-aut-sei=Kohsaka
en-aut-mei=Mutsutoshi
kn-aut-name=高坂睦年
kn-aut-sei=高坂
kn-aut-mei=睦年
aut-affil-num=1
ORCID=

en-aut-name=KobayashiJunzo
en-aut-sei=Kobayashi
en-aut-mei=Junzo
kn-aut-name=小林潤三
kn-aut-sei=小林
kn-aut-mei=潤三
aut-affil-num=2
ORCID=

en-aut-name=TsujiHarunori
en-aut-sei=Tsuji
en-aut-mei=Harunori
kn-aut-name=辻治憲
kn-aut-sei=辻
kn-aut-mei=治憲
aut-affil-num=3
ORCID=

en-aut-name=IzumiyaKazunori
en-aut-sei=Izumiya
en-aut-mei=Kazunori
kn-aut-name=出宮一徳
kn-aut-sei=出宮
kn-aut-mei=一徳
aut-affil-num=4
ORCID=

en-aut-name=NagaoTakashi
en-aut-sei=Nagao
en-aut-mei=Takashi
kn-aut-name=長尾堯司
kn-aut-sei=長尾
kn-aut-mei=堯司
aut-affil-num=5
ORCID=

en-aut-name=FujiwaraTsunehiro
en-aut-sei=Fujiwara
en-aut-mei=Tsunehiro
kn-aut-name=藤原恒広
kn-aut-sei=藤原
kn-aut-mei=恒広
aut-affil-num=6
ORCID=

en-aut-name=KikuiShigeru
en-aut-sei=Kikui
en-aut-mei=Shigeru
kn-aut-name=菊井茂
kn-aut-sei=菊井
kn-aut-mei=茂
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部精神々経科

affil-num=2
en-affil=
kn-affil=岡山大学医学部精神々経科

affil-num=3
en-affil=
kn-affil=岡山大学医学部精神々経科

affil-num=4
en-affil=
kn-affil=岡山大学医学部精神々経科

affil-num=5
en-affil=
kn-affil=岡山大学医学部精神々経科

affil-num=6
en-affil=
kn-affil=岡山大学医学部精神々経科

affil-num=7
en-affil=
kn-affil=岡山大学医学部精神々経科
END

start-ver=1.4
cd-journal=joma
no-vol=80
cd-vols=
no-issue=5-6
article-no=
start-page=527
end-page=539
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1968
dt-pub=19680630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Re-Appraisal on the Rate of Parasite Carriers Estimating the Rate of Parasite Carriers in Community by using the Results of Mass Examination of Feces in the Fields of School Health Practice
kn-title=寄生虫保卵率の再検討 学童保卵率と地域住民保卵率との相関
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=There is a great need for prevention against parasitosis in the field of community health, though in actual practice, the mass examination for parasite carriers has not succeeded to get enough rate of receiving the examination. Because of this problem the author has investigated the conditions the performance of health practice against parasitosis, systematically. In order to get some criteria for the evaluation of the parasite control in communities, the author has investigated statistically the results of parasitic egg examination among general residents comparing to those of the school children at the same communities on O-prefecture. The objects were selected among the areas in this prefecture officially designed for "the promotion of preventive practice against ancylostomiasis". The studies have been carried out statistically and the results checked by the field surveys to learn the social factors influencing the receiving rate of examination and the efficiency of the practice. The results of the studies have been as follows: 1) By examining annual change of correlation between the rates of general residents and those of the school children in the same communities, there have been observed differences among the kinds of parasites. 2) Concerning "the special areas for preventive practice against ancylostomiasis" the parasite carries among the children has showed high correlation with those among general residents at the beginning of the designation as the special areas. This correlation has changed as the preventive practice proceeded. About ascariasis and other parasitoses, the correlation between the children and general residents have maintained relatively unchanged in high value. The differences of the elapse between the numbers of ancylostomiasis and the others could be derived from the ecological specialities and the mode of infection. 3) Correlation between the residents and children was high in ancylostomiasis when the receiving rate was over 80% and the same could be said in ascariasis when it was over 60%. 4) Also high correlation were observed between 1 to 3% of ancylostomiasis among school children, and under 15% of ascariasis among them. 5) These statistical results have been investigated expecting to get some criteria for evaluation of preventive practice. 6) The results of field survey about factors influencing on these data have been described.
en-copyright=
kn-copyright=

en-aut-name=KatoShyoji
en-aut-sei=Kato
en-aut-mei=Shyoji
kn-aut-name=加藤尚司
kn-aut-sei=加藤
kn-aut-mei=尚司
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部衛生学教室
END

start-ver=1.4
cd-journal=joma
no-vol=82
cd-vols=
no-issue=9-10
article-no=
start-page=431
end-page=434
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1970
dt-pub=19701030
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Urinary trichloroethanol and trichloroacetic acid excretion in workers exposed to various concentration of trlchloroethylene in an automobile parts factory (Part 1. Studies on trichloroethylene poisoning)
kn-title=三塩化エチレン気中濃度と暴露後の尿中，三塩化エタノール，三塩化酢酸の排泄量との関係 第1報 三塩化工チレン中毒の研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In order to know the relationship between concentration of trichloroethylne and the amount of urinary trichloroethanol or trichloroacetic acid, average concentration of trichloroethylene inhaled by the workers in an automobile parts factory was measured by Kitagawa detector tube at 20-minute's interval. And urinary trichloroethanol and trichloroacetic acid were determined by Ikeda's oxidation method of chromium trioxide and our direct colorimetric
method. The results were as follows. 1. Straight relationship between trichloroethylene concentration in the air and trichloroethanol or trichloroacetic acid in the urine was recognized by Ikeda's method. 2. Urinary trichloroethanol and trichloroacetic acid concentrations in workers exposed to trichloroethylene were determined by both our direct colorimetric method and Ikeda's oxidation method of chromium trioxide. Correlation between urinary trichloroethanol and trichloroacetic acid determined by Ikeda's method and our direct colorimetric method was observed.
泄されるのであろうと言つている.1946年,Forssman,Ahlmark(2)3))はトリクレン蒸気中で働く労働者の訴えと,その尿中三塩化酢酸濃度との関係を見い出し,その75mg/lがトリクレン中毒の警戒すべき限界であると報告した.これに対して,1950年,Frant,Westeadorp(4))は,環境に気中のトリクレン濃度100ppmのもとで働く場合,その尿中には200mg/l濃度の三塩化酢酸を含むと述べられている.現在までは,三塩化酢酸の許容濃度はFrantの成績より75mg/lであるとしている.又,トリクレンの尿中代謝産物には三塩化エタノールのグルクロン酸抱合物もあり,soucek and Vlachova(5))等は1964年に,三塩化エタノールは,三塩化酢酸より排泄量が多く,しかも,排泄速度がはやい事を報告している.著者は実際の作業場で,三塩化エタノール,三塩化酢酸の関係を調べ,気中濃度との関係を求めた.又,三酸化エタノールの定量を池田氏の方法に比べて,簡便な定量を見いだした.そして作業者の尿を用いて,著者等の方法と池田氏の方法との相関を調べた.その成績をここに報告する.
en-copyright=
kn-copyright=

en-aut-name=TakatsukaYoshiko
en-aut-sei=Takatsuka
en-aut-mei=Yoshiko
kn-aut-name=高塚住子
kn-aut-sei=高塚
kn-aut-mei=住子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部公衆衛生学教室
END

start-ver=1.4
cd-journal=joma
no-vol=86
cd-vols=
no-issue=11-12
article-no=
start-page=593
end-page=612
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1974
dt-pub=19741230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Visual Evoked Responses from the Human Thalamus
kn-title=光刺激による誘発反応の視床一皮質相関に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Visual evoked responses (VER) were recorded from the thalamus and the scalp during stereotaxic thalamotomy in our service. The study involved fourteen patients with various involuntary movement disorders and intractable pain. Routine monopolar EEGs were recorded, from the ventrolateral nuclens and the centremedian of the thalamus, with multipolar electrodes and from the vertex and the occipital region with needle electrodes simultaneously. VERs have been analysed by means of averaging techniques as well as spectral analysis of the EEGs. Experimental studies were also performed with chronically implanted electrodes in the ventrolateral nucleus, the lateral geniculate body, the visual cortex and the anterior sigmoid gyrus of the cats. The results were as follows: 1) Visual evoked responses (VERs) from the occipital regions were well demonstrated in seven out of fourteen cases. The responses had typical seven components (�T-�Z) with rhythmic after-discharge, documented by Ciganek's report. 2) The evoked responses from the vertex showed practically no early components. Therefore, four components of the response, namely P(1), N(1), P(2) and N(2), were started with P(1) of the peak latency of 105.2msec. This response was corresponded to so-called vertex potential, of which pattern had no similarity to the VER from the occipital region. 3) The evoked responses from the human thalamic VL and CM nuclei showed very similar patterns to the vertex potentials with four components. Peak latencies of them were noted P(1) with 96.4±12.8msec, N(1) with 134.6±19.4msec, P(2) with 196.0±25.5msec and N(2) with 260.9±29.3msec. The thalamic responses always tended to lead off the vertical one about 8.8 to 18.3msec in all cases. 4) In the animal (cat) experiments, VER from visual cortex showed similar pattern to the one from the lateral geniculate body, and VER from the thalamic VL nucleus resembled to the one from the anterior sigmoid gyrus. 5) Rhythmic after-discharges were noted in the thalamus as well as the vertex after their wave components. The after-discharges of the vertex were not disappeared after VL thalamotomy, while spontaneous spindle discharges were disappeared after the thalamotomy. Therefore, rhythmic after-discharges were thought to be involved some other physiological mechanisms to that of spantaneous spindle activity. 6) Spectral analysis of EEGs showed high value of coherence between the thalamic and thevertical EEGs before and during photic stimulation. On the other hand, low coherence were obtained between the vertical and the occipital EEGs in all cases. 7) Photic stimulation provoked VERs in the occipital cortex as well as the vertex potentials through the VL or CM nucleus of the thalamus. It is most interesting that, while the VL nucleus is known as one of specific thalamic nuclei physiologically, the nucleus is also concerned with one of non-specific response such as vertex potentials.
en-copyright=
kn-copyright=

en-aut-name=MatsumotoYuzo
en-aut-sei=Matsumoto
en-aut-mei=Yuzo
kn-aut-name=松本祐蔵
kn-aut-sei=松本
kn-aut-mei=祐蔵
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部脳神経外科学教室
END

start-ver=1.4
cd-journal=joma
no-vol=88
cd-vols=
no-issue=11-12
article-no=
start-page=1079
end-page=1092
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1976
dt-pub=19761230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Hypothalamic-hypophysial-adrenal function in acute and chronic schizophrenic patients and the role of the frontal lobe cortex to the adrenal system
kn-title=精神の興奮及び荒廃と体内コルチコイド代謝との相関について（血液,脳脊髄液分布）
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Cortisol and corticosterone were measured on 27 excited acute schizophrenic patients, 17 deteriorated chronic schizophrenic patients, and 16 general paresis patients. Cortisol and corticosterone were concurrently measured by the Van der Vies fluorimetric procedure. ACTH (water soluble regular ACTH) at 25 I.U. was injected once intramuscularly. Blood and cerebrospinal fluid (CSF) samples were collected one week prior to and 120 minutes after the ACTH injection. The results were as follows: 1. The mean total blood concentrations of cortisol and corticosterone were higher in the general paresis group than in either schizophrenic group. Almost no difference was present between the acute schizophrenic group and the chronic schizophrenic group. Blood concentrations of corticosterone were higher in the chronic schizophrenic group and general paresis group than in the acute schizophrenic group. The ratio of blood cortisol to corticosterone was high in the acute schizophrenic group while the chronic schizophrenic group and general paresis group showed low ratios. 2. Blood cortisol levels of the acute schizophrenic group and the general paresis group were markedly increased after ACTH administration, but the chronic schizophrenic group did not show such a marked increase. 3. The blood corticosterone level of the chronic schizophrenic group decreased after ACTH administration. This finding suggests that ACTH administration might induce some unknown responses on the metabolic pathway from progesterone to cortisol or from progesterone to corticosterone. 4. The ratios of blood cortisol to corticosterone induced by ACTH injection were reversed between the acute schizophrenic group and the chronic schizophrenic group, due presumable to the inefficient increase of cortisol in the chronic schizophrenic group. 5. Blood and CSF corticoid levels were high in the general paresis group. This may be due to atrophy of the frontal lobe cortex and impairment of the blood-brain barrier. 6. The ratios of plasma cortisol to CSF cortisol before and after ACTH administration were almost the same. However, the ratios of plasma corticosterone to CSF corticosterone before and after ACTH administration differed.7. Blood and CSF corticoid levels of the chronic schizophrenic group before and after ACTH injection indicated that this group had a distinctive response pattern compared to the acute schizophrenic group. 8. A characteristic feature of the chronic schizophrenic group was a decreased response to ACTH injection and a high level of plasma corticosterone. 9. Atrophy of the frontal lobe cortex seemed not to interfere with the acute stress response.
en-copyright=
kn-copyright=

en-aut-name=NagaoTakashi
en-aut-sei=Nagao
en-aut-mei=Takashi
kn-aut-name=長尾堯司
kn-aut-sei=長尾
kn-aut-mei=堯司
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部脳代謝研究施設病態生化学部門
END

start-ver=1.4
cd-journal=joma
no-vol=88
cd-vols=
no-issue=3-4
article-no=
start-page=177
end-page=183
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1976
dt-pub=19760430
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Diagnosis and treatment of acute rejection after kidney homotransplantation in dog Part 2. Correlation between the effect of a large dose of methylprednisolone administration and the finding of transplanted kidney tissue
kn-title=犬同種腎移植後の急性拒絶反応に対する診断と治療に関する研究 第2編 メチルプレドニン大量投与の効果と移植腎組織所見の相関について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=For the acute rejection after kidney homotransplantation in dogs when 20 mg/kg/day of MPSS (methylprednisolone) had been administered for 3 days, serum creatinine recovered from 3.4 mg/dl to 2.4 mg/dl, and the rejection was successfully inhibited in 13 cases (93%) out of 14. By histological findings 4 out of 6 cases showed a marked improvement of cell infiltration, 2 cases a slight improvement, and there was not a single case showing any increase of cell infiltration. As the complication of MPSS administration, there could be observed pneumonia and hemorrhage in the upper alimentary canal. Pneumonia occurred in 4 cases (29%) out of 14, of them 3 cases (21%) died from pneumonia. Hemorrhage in the upper alimentary canal was observed in 2 cases (14%) of the 14 studied.
en-copyright=
kn-copyright=

en-aut-name=TanakaKohki
en-aut-sei=Tanaka
en-aut-mei=Kohki
kn-aut-name=田中浩毅
kn-aut-sei=田中
kn-aut-mei=浩毅
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=89
cd-vols=
no-issue=9-10
article-no=
start-page=1165
end-page=1176
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19771030
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies of collagenase in malignant tumors 2. The collagenolytic activity and its relation to the development of human stomach cancer
kn-title=悪性腫瘍とcollagenase 第2編 胃癌の進展とcollagenase活性
en-subtitle=
kn-subtitle=
en-abstract=The role of collagenase has been investigated associated with the stromal changes of tumors which were known as degradation or resorption of collagen possibly. This time collagenolytic activity of 38 cases of human stomach cancer was measured by the culture methods of Gross and Lapiere and histological observation was performed simultaneously to examine the relationship between collagenolytic activity and morphological pattern of the gastric cancer. As the following results show the collagenolytic activity might be seemed to concern to the strength and direction of the invasion of gastric cancer. 1). In the tissues of gastric cancer collagenolytic activity was significantly higher than in normal stomach tissues. 2). The strongest collagenolytic activity in gastric cancer was observed in the spreading front and the second was the center of the tumor. In the surrounding of cancer the collagenolytic activity was only slightly higher than in normal stomach. 3). Histologically the more poorly differentiated, the higher collagenolytic activity, and in the medullary type of the poorly differentiated adenocarcinoma the activity was stronger than in the scirrous type. 4). Relating to the infiltrative pattern the collagenolytic activity was the highest at the spreading front of INF β and second was the same region of INF γ, interesting to say, the activity in the surroundings of such front was obviously increased. 5). Borr. IV type cancer showed the collagenolytic activity elevated in every part of the lesion. In contrast, this activity was weak in 0 and 5 type in the macroscopical classification. 6). Collagenolytic activity was significantly high at the mucosal spreading front of the superficial spreading type of the early gastric cancer, namely the collagenolytic activity was associated with the horizontal direction of development of this type of the cancer.
kn-abstract=胃癌38例について癌胃各部のco1lagenase活性を,組織培養法により測定し,形態学的特徴とcollagenase活性の相関を追求し,腫瘍の進展におけるcollagenaseの役割を検討した.結果は,癌胃全体では癌の進展先進部で最も高い活性がみられ,組織型別にみると,低分化傾向を示す癌ほど活性が高いと同時に,低分化腺癌の髄様型ではとくに高活性であった.進展形式についてみると, INFβの進展先進部の活性が高く,また表層拡大型早期癌の粘膜進展先進部で高活性であり,癌の進展の強さや方向とともに癌細胞密度とcollagenase活性は,相関する傾向を示した.
en-copyright=
kn-copyright=

en-aut-name=MimuraTetsushige
en-aut-sei=Mimura
en-aut-mei=Tetsushige
kn-aut-name=三村哲重
kn-aut-sei=三村
kn-aut-mei=哲重
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一外科学教室
END

start-ver=1.4
cd-journal=joma
no-vol=89
cd-vols=
no-issue=7-8
article-no=
start-page=865
end-page=875
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19770830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Correlation between cancer progress and activity of cancer-bearing host lymphocyte
kn-title=癌進展性と担癌生体リンパ球の有する活性の相関
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=As a link in the studies on biological activity of lymphocytes in the mice transplanted with Ehrlich ascites cancer and in cancer patients the correlation between machrophage migration inhibitory activity (MIF-activity) and the progress of cancer was investigated, and the results are presented briefly as follows. 1. MIF activity in the mouse transplanted s.c. with 5x10(6) Ehrlich cancer cells first appears markedly in the regional lymph nodes and the MIF activity disappears about 10 days after the cancer transplantation. 2. In three cases (8.6%) out of 36 having benign diseases MIF activity is positive. 3. In measuring the MIF activity of peripheral blood lymphocytes of 71 gastric cancer patients before operation, those showing positive or pseudo-positive activity of MIF are 24 cases, being 33.9% of the total. MIF activity of peripheral blood lymphocytes before operationin the cases of Stage II is 41.7% , in those of Stage III it is 29.0% and in those of Stage IV it is 15.4% , indicating that the positive rate of MIF declines as the cancer progresses. Lymphocytes of the lymph nodes extirpated during operation show a similar tendency. 4. In comparing MIF activity of peripheral blood lymphocytes of gastric cancer patients before operation with that after operation, the activity in Stage II before operation is 41.7% as against 0% after operation, that in Stage III it is 29.0 % before operation and 10.5% after operation, showing amarked decrease, while that in Stage IV, in contrast, rises from 15.4% to 23.1%. Usually the MIF activity disappears when tumor removal is completely performed, but in the cases of progressive cancer the MIF activity seems to be sustained. 5. Looking at the cross reaction, in gastric cancer cases with positive MIF activity for autochthonous antigen they show 42.9% positivity against heterogenous antigen. Besides we have observed the cross reaction between gastric cancer and colon cancer as well as between colon cancer and gastric cancer. The foregoing findings indicate that in human cancer just as in animal cancer MIF activity first appears in the regional lymph nodes, which tends to decrease and disappears as the cancer advances. Since there can be observed a marked cross reaction between gastric cancer patients, MIF would serve as a useful criterion for the discovery of gastric cancer and for the determination of prognosis.
en-copyright=
kn-copyright=

en-aut-name=UchidaYoshio
en-aut-sei=Uchida
en-aut-mei=Yoshio
kn-aut-name=内田善夫
kn-aut-sei=内田
kn-aut-mei=善夫
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=92
cd-vols=
no-issue=7-8
article-no=
start-page=989
end-page=993
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1980
dt-pub=19800831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on Donaggio Reaction and Micro-determination of urinary protein Part �U. Correlation between titer of Donaggio Reaction and α1-acid glycoprotein and albumin in the urine of before and after running
kn-title=Donaggio反応及び尿微量蛋白定量法に関する研究 第2報 スポーツ前後尿におけるDonaggio反応値,α1-acid glycoprotein濃度,Albumin濃度の相関関係について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Correlation between Donaggio-titer, on one hand and α1-acid glycoprotein and albumin on other in the urine of students before, after running was calculated correlation between increasing amounts of Donaggio-titer on one hand and α1-acid glycoprotein and albumin on the other in the urine of students after running was also calculated. 1) Correlation between values of Donaggio-titer and α1-acid glycoprotein was nice. 2) Correlation between values of Donaggio-titer and urinary albumin was lower than that between values Donaggio-titer and urinary α1-acid glycoprotein. 3) Tendency to be correlation between urinary α1-acid glycoprotein and urinary albumin was observed. 4) Regression between of Donaggio-titer on one hand and urinary α1-acid glycoprotein and urinary albumin on the other was made. 5) From above results it was concluded that Donaggio-titer in urine before and after a hard running was estimated from the concentration of ruinary α1-acid glycoprotein and urinary albumin.
en-copyright=
kn-copyright=

en-aut-name=MatsuiYoshinori
en-aut-sei=Matsui
en-aut-mei=Yoshinori
kn-aut-name=松井義典
kn-aut-sei=松井
kn-aut-mei=義典
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部公衆衛生学教室
en-keyword=Donaggio reaction
kn-keyword=Donaggio reaction
en-keyword=α1-acid glycoprotein
kn-keyword=α1-acid glycoprotein
en-keyword=albumin
kn-keyword=albumin
en-keyword=Correlation
kn-keyword=Correlation
END

start-ver=1.4
cd-journal=joma
no-vol=92
cd-vols=
no-issue=5-6
article-no=
start-page=675
end-page=684
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1980
dt-pub=19800630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A new non-invasive method for cardiac output measurement by combining an ultrasonic Doppler method to an ultrasonic echocardiography
kn-title=超音波ドプラー法と超音波カルディオグラフィ法の併用による非観血的心拍出量測定法
en-subtitle=
kn-subtitle=
en-abstract=It is a well-known fact that knowing cardiac output and blood flow volume in a certain region of the body is of importance not only in clinical practice but also in physiology. Furthermore, it would be ideal if they were measured, simply, non-invasively and repeatedly without torture to patients. The ultrasonic Doppler method has been believed to be suitable and modified for this purpose. However, critical shortcoming in this method is that this method lacks quantitative determination because sectional area of the vessels is unknown. This study was to develop a new non-invasive method of determining blood flow volume by combining echocardiography to Doppler method. Echocardiography is able to determine the diameter of the vessels and Doppler method simultaneously determines blood flow velocity in it. Then, blood flow volume becomes obtainable. This study of applying Doppler and echocardiographic probes in a short interval showed a good correlation of blood flow volume obtained with this method to that obtained with electromagnetic method. It was also found that cardiac output was obtainable by measuring the blood flow volume of the common carotid artery with the method. Correlation coefficient (r) between the diameter obtained by echocardiography and that measured with a ruler was 0.99 with a regression equation of y=0.89x + 0.22 (p<0.001). r between blood flow volume obtained with this method and that measured by electromagnetic probe was 0.96 with y=0.928x - 0.03 (p<0.001). Estimation of cardiac output from the blood flow volume of the left common carotid artery, which was determined with this method, was accurate with r=0.90 (y=37.08 + 18.9, p<0.001). With these data, it was concluded that this new method, namely, a combination of Doppler method and echocardiography, was accurate enough to clinical use to determine regional blood flow volume and it was also available to estimate cardiac output from the blood flow volume of the left common carotid artery. Moreover, this new method is measurable repeatedly without invasion and torture to patients with simple technique.
kn-abstract=近年,方向指示型超音波ドプラー血流計による末梢動脈,ことに総頸動脈の血流波形と心拍出量との関連を分析した報告がみられるようになった.これらの報告は非観血的に超音波ドプラー血流計を用いて,血流速度を連続的に測定しながら負荷を与えたり,術中,術後の心拍出量の変化を経時的に追う方向の有効性を強調している.しかし,こうした測定法では精度に関する限り,非観血的であるという理由からそれほど厳しい要求をなされていない.これらの欠点よりも経時的な相対変化を簡単に,無侵襲で追跡できるという他の追従を許さない特徴を活用できるため,外科臨床においても,術後の患者の経過観察の目的で心拍出量を知るための重要なパラメーターとなりうることによって有力な手段とされてきた.本研究は血流波形の分析のみならず,流量の定量化を試みたもので,超音波ドプラー法と超音波カルディオグラフィの組合せにより,一方の短所を他方の長所で補うことで好結果を得た.超音波ドプラー法で血流速度を経時的に計測し,同時に超音波カルディオグラフィによってその時々の血管径を計測し,波形の積分により流速を算出し,血管径より血管断面積を乗じて血流量の測定を試みた.実験方法は,左総頸動脈流量を中心に行い,流量の基準として電磁流量計を用いた.電磁流量計によって得られた心拍出量と,左総頸動脈の流量比の相関をだし,逆に左頸動脈の流量より心拍出量の推定を行ったものである.実験犬数は15頭で,電磁流量計でえられた左総頸動脈流量は超音波ドプラー法と超音波カルディオグラフィ法によってえられた流量の相関は,y=0.92x-0.03,r=0.96,P<0.001と高い相関関係を示し,さらに,この流量より心拍出量を推定した10例では,y=37.0x+18.9(r=0.90,p<0.001)の結果をえた.本法の臨床応用にあたっては非観血的であるだけに繰返し簡単に,しかも無侵襲に行いうるものであり,術後患者の経過観察のための重要なパラメーターとして好結果を期待できるものである.
en-copyright=
kn-copyright=

en-aut-name=OhyaAtsuo
en-aut-sei=Ohya
en-aut-mei=Atsuo
kn-aut-name=大屋厚夫
kn-aut-sei=大屋
kn-aut-mei=厚夫
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第2外科教室
en-keyword=非観血的血流量
kn-keyword=非観血的血流量
en-keyword=非観血的心拍出量
kn-keyword=非観血的心拍出量
en-keyword=超音波ドプラー法
kn-keyword=超音波ドプラー法
en-keyword=超音波カルディオグラフィ法
kn-keyword=超音波カルディオグラフィ法
END

start-ver=1.4
cd-journal=joma
no-vol=92
cd-vols=
no-issue=1-2
article-no=
start-page=125
end-page=135
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1980
dt-pub=19800228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Comparison of self-completion vs personal interview methods in a survey of respiratory symptoms
kn-title=呼吸器症状調査における自己記入方式と個別面接方式の比較 ―とくに,自己記入方式による地域評価の意義について―
en-subtitle=
kn-subtitle=
en-abstract=The level of pollutants, especially SOx, are becoming lower in the air. The prevalence rates of respiratory symptoms such as cough and phlegm are also decreasing, but the sampling size must be increased to know the effects of air pollution. Self-completion methods have the merit of increasing the sampling size, but the reliability of self completion method has been argued. In previous studies, agreement between the prevalence rates of self-completion methods and those of personal interview was tested. But this agreement is not considered to be always necessary, if a specific relationship between the two methods is observed in the range of the prevalence rate. From this point of view, the correlation and regression analyses of cough, phlegm, dyspnea and asthma symptoms were made, and the reliability of the self-completion method discussed. The data of 19 districts in Okayama prefecture was used, where surveys using both methods were attempted. The questionnaire for the personal interview method was the BMRC's standard questionnaire, and the questionnaire for self-completion method was made by referring to the CMI's and other self-completion questionnaires. The results were obtained as follows: 1. On regression analyses, the regression coefficients were statistically significant in many cases (p<0.01 for eight cases and p<0.05 for three out of twelve cases). 2. The correlation coefficients between the two methods were large, especially for the analyses of cough and phlegm. For phlegm, the lower limits of 95% confidence interval of correlation coefficients ranged from 0.833 to 0.982. For cough, it ranged from 0.630 to 0.941. 3. From the results of 1 and 2, it was considered that the self-completion method using a simple questionnaire was as useful as the personal interview method to study the prevalence of cough and phlegm in the districts.
kn-abstract=大気汚染の人体におよぼす影響に関して,疫学の分野では,持続性せき.たん有症率,慢性気管支炎有症率など呼吸器症状に関する指標が,影響の有無を検証するための指標として用いられてきた(1〜10)).この呼吸器症状に関する指標は種々の質問を用いた住民調査によって得られるが,なかでもBMRCの質問票は標準的な質問票として広く用いられてきた.BMRCの質問票は面接方式を原則として開発されたものであるが,面接方式は自己記入方式に比較して人的・時間的コストが大きく,自己記入方式で実施された例もある(5, 7)).また,一方,我が国における大気汚染物質濃度は,特に硫黄酸化物を中心として低下しており,これに伴って有症率の低い地域の調査が重要となってきた.春日ら(9))は,このように有症率の低い地域の調査では,母有症率の推定範囲が有症率の大きさに比較して広い範囲となることを強調している.さらに,大気汚染以外の因子(性・年令・喫煙歴などの他,職業歴・既往歴など)が有症率の大きさを変動させる重要な因子となってくる.従って,春日ら(9))も述べているように,今後の調査に於ては,大きなサンプル・サイズが必要となってくると考えられる.そして,自己記入方式は,大きなサンプル・サイズを得る方法としての利点を有しているため,この方式の意義を論じることは重要と考えられる.従来より,自己記入方式で実施して得た有症率(質問によっては有訴率という表現の方がより適当と思われる場合があるが,以下ではこれらも含めて有症率という)の信頼性について,面接方式と比較した多くの報告がある(7〜10)).表-1にこれらの報告の研究方法を示した.従来の報告の第一のタイプ(表-1・A)は,同一対象者に対し,面接と自己記入の2方式で調査を実施し,〔回答が一致するか?〕に注目した報告である(7,8)).米国のCHESS(l1))は常俊ら(8))の報告を一つの根拠として,自己記入方式を採用したと述べている.このタイプの報告は,解析方法からみると〔自己記入法が面接法と同一とみなし得るか否か〕を検証したものといえる.しかしながら,2つの方式からは本質的には異なる調査成績が得られるのであり,〔2つの方式を同一とみなし得なくても,2方式間に特定の関係が有症率の持定のrangeにわたって成立するならば,少なくともそのrange内では自己記入方式によっても有症率の比較が可能である〕といえる.従って,自己記入方式の意義を論じる上で,〔本質的に異なる調査方式をその同一性を証明しようとする解析〕によって論じることは,必須ではなく,むしろ,2つの方式で得た地区ごとの有症率の間に〔特定の関係が成立するか否か〕,そして〔その関係は密接であるか否か〕に注目した解析が必要と考えられる.例えば,自己記入方式の有症率が面接方式の有症率の2倍であったとしても(この場合,一致率は50% と低いが),この関係が一定のrange内で成立すれば,自己記入方式の信頼度は面接方式と同等といえる.最近,別のタイプの報告がなされた.春日ら(9))(表-1・B)は,異なる抽出法による2種の対象者に一方は面接方式で,他方は自己記入方式で調査した.彼らは,第一のタイプと同様に有症率の一致性に注目して,〔2種の対象者の有症率の差の検定〕を行ったが,さらに喫煙量別有症率の加令による変化,および年令階級別有症率の喫煙による変化を観察し,2方式の有症率の変化が同様の傾向を示したと述べた.これは,〔2方式の有症率の間に,低い有症率(若年層又は非喫煙者)から高い有症率(高年令層又は高度喫煙者)にわたって,密接な関係があるであろう〕と示唆するものである.久米ら(10))(表-1・C)は,2方式の有症者の一致状況をみると共に,岡山県の行なった面接方式による調査地区群と自己記入方式による調査地区群の中で久米らの調査した地区が,2方式共に,それぞれほぼ同様の相対的位置を示したと述べている.以上のように,第1のタイプ(表-1・A)は,もっぱら2方式の同一性に注目しているが,第2のタイプ(表-1・B・C)は,有症率のrangeを考慮している.第1のタイプでは,有症率のより高い地区,あるいはより低い地区においても,2方式の一致性が成立するか否かについては言及できない.これに対し,第2のタイプは有症率のrangeを考慮しているが,データの記述的観察を主としている.従って著者(表-1・D)は,岡上県の行なった19地区の成績を用いて比較的広い有症率のrangeにわたって,2方式の間に特定の関係があると言えるか否かまたその関係は密接であるか否かを回帰分析・相関分析によって検証することを試みた.
en-copyright=
kn-copyright=

en-aut-name=TsubotaNobutaka
en-aut-sei=Tsubota
en-aut-mei=Nobutaka
kn-aut-name=坪田信孝
kn-aut-sei=坪田
kn-aut-mei=信孝
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部公衆衛生学教室
en-keyword=自己記入方式
kn-keyword=自己記入方式
en-keyword=面接方式
kn-keyword=面接方式
en-keyword=BMRC標準化質問票
kn-keyword=BMRC標準化質問票
en-keyword=大気汚染影響
kn-keyword=大気汚染影響
END

start-ver=1.4
cd-journal=joma
no-vol=91
cd-vols=
no-issue=7-8
article-no=
start-page=905
end-page=927
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1979
dt-pub=19790830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Relationship between thalamic and scalp alpha rhythms in man -with cross-spectral analysis-
kn-title=ヒトの視床脳波と頭皮上脳波のαリズムの相関に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Thalamic and acalp EEGs were recorded simultaneously during stereotaxic surgery. Thalamic EEGs were recorded from the ventro-lateral (VL) nucleus of the thalamus in 19 patients with parkinsonism, and from the centre median (CM) nucleus in 3 with intractable pain. Scalp EEGs following thalamotomy were also recorded. These EEGs were analyzed quantitatively by means of cross-spectral analysis. The relationships between thalamic and scalp alpha rhythms and postoperative changes of scalp alpha rhythms were studied to investigate the hypothesis that the cortical alpha rhythms are paced by thalamic generators. The results were as follows: 1) The alpha rhythms in the thalamic VL and CM nuclei had the same frequency components as those in the scalp, and were more regular and predominant than those in the scalp. 2) Significant coherences were found between alpha rhythms in the thalamic VL and CM nuclei and those in the bilateral frontal, central and parietal scalp regions. The stronger coherences were found between VL thalamic alpha rhythms and frontal and central ones, and between CM thalamic alpha rhythms and central and parietal ones. 3) Among these alpha rhythms, there were found constant phase relationships that the alpha rhythms from the VL or CM thalamic nucleus were followed, in the order of time lag, by the scalp ones in the frontal, central and then parietal regions without interhemispheric phase lag. Interhemispheric time lag was not found. 4) The alpha-coherences between the contralateral central scalp region and the VL or CM nucleus were apt to be stronger than those between the two hemispheres.5) The alpha-coherences between the central scalp region and the CM nucleus were stronger than those between the central scalp region and the dorsomedial nucleus. 6) Intrathalamic and intrahemispheric alpha-coherences were stronger than those between thalamus and scalp. Intrathalamic alpha-coherences were the strongest and had a broad bandwidth. 7) Following VL or CM thalamotomy, alpha rhythms in the frontal, central and parietal regions slowed and became irregular in frequency, but the phase relationships in these alpha rhythms remained the same as preoperative ones which spread in anteroposterior direction. However, the coherences between the fronto-centro-parietal alpha rhythms and the occipital alpha rhythms became lessened and the phase lag between parietal and occipital alpha rhythms was prolonged. On the basis of these findings, it seems to indicate that the thalamus, with close intrathalamic and internuclear relationships, has an ability to generate more stable and regular alpha rhythms than the cortex, and that the individual thalamic nucleus has the ability to generate intrinsic alpha rhythms and to regulate the alpha rhythms arising in the cortical area which receives projections from the thalamic nucleus. It also suggests that the alpha rhythms in the fronto-centro-parietal cortex, with close relationships with VL and CM nucleus, are different to some degree in synchronization from the occipital alpha rhythms.
en-copyright=
kn-copyright=

en-aut-name=MimuraYasunaga
en-aut-sei=Mimura
en-aut-mei=Yasunaga
kn-aut-name=三村恭永
kn-aut-sei=三村
kn-aut-mei=恭永
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部脳神経外科教室
en-keyword=脳波
kn-keyword=脳波
en-keyword=視床脳波
kn-keyword=視床脳波
en-keyword=αリズム
kn-keyword=αリズム
en-keyword=スペクトル分析
kn-keyword=スペクトル分析
en-keyword=定位脳手術
kn-keyword=定位脳手術
END

start-ver=1.4
cd-journal=joma
no-vol=94
cd-vols=
no-issue=5-6
article-no=
start-page=471
end-page=485
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1982
dt-pub=19820630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Analgestic effect of histamine
kn-title=ヒスタミン脳内投与による鎮痛作用発現について
en-subtitle=
kn-subtitle=
en-abstract=All the test drugs were dissolved in saline and a fixed amount of 0.5μl was injected into the lateral ventricle of conscious mice (dd-Y, male). Injection of the same amount of saline exhibited a negligible effect. After mice were injected intraperitoneally with 0.1ml/10g of 0.02% aqueous solution of phenylquinone or 0.6% acetic acid solution, the number of writhing syndrome was counted for 30min. When histamine (Hi) was given immediately after intraperitoneal injections of those chemical stimulants, Hi displayed a protective effect and the number of writhes decreased significantly at doses higher than 5μg/body dose-dependently. Electrical stimulation (25V, 1Hz, 25msec) to the mouse tail evokes a squeak response with the mean reaction time of 5.6±0.4 sec. When Hi was applied, the reaction time was prolonged significantly at the doses higher than 10μg/body in a dose-dependent fashion. A similar analgesic effect of Hi was also displayed in a hot plate method which was carried out at 55℃. In this case, application of 10μg or more of Hi definitely prolonged the pain reaction time. When morphine was given subcutaneously at the dose of 3mg/kg which is less than the minimum effective dose, morphine augmented the analgesic effect of Hi. In accordance with this, pretreatment of naloxone (0.01mg/kg) antagonized the analgesic action of Hi almost completely. Further, by injecting the subthreshold dose of leucine-enkephalin (5mg/kg) prior to Hi administration, analgesic effect of the latter was enhanced. When the H(1)-receptor blocking agent, diphenhydramine was injected simultaneously with Hi either intraventricularly or intravenously at the doses less than affecting the reaction time in a hot plate method, it antagonized the analgesic action of Hi. However, the administration of H(2)-receptor blocking agent, cimetidine was not effective in antagonizing the Hi action. From these findings, it was concluded that Hi injected into the ventricle reveals some analgesic actions which appear via H(1) receptor and the mechanism of Hi analgesia may be related in some way to the enkephalinergic mechanism.
kn-abstract=中枢神経系に関するcatecholamine(CA)や5-hydroxytryptamine(5-HT)の生化学的及び薬理学的研究に比較すると,Histamine(Hi)の中枢作用は最近急速に注目を浴びてはいるが,まだ充分には理解されていない.しかし,哺乳動物の中枢神経系内におけるHiの分布は,CAや5-HTと極めて類似し,特に下垂体や視床下部には高濃度に分布する事が知られており(1)),Hiも中枢神経系においてneurotransmitterまたはneuromodulatorとしての役割を果している可能性は高いと考えられている(2)).Feldbergら(3))は,無麻酔ネコの側脳室にHi 100μg/bodyを注入した際,ネコの活動性が低下し,傾眠や筋力低下が観察される事を報告している.最近,Nowakら(4))はHiをラット脳室内に投与した際,運動量の低下やcatalepsyの発現がみられる事を報告している.また,ラット脳室内へのHi投与後に,動脈血圧が上昇する事も知られている(5)).マウスの場合には,Hiの脳内投与後体温下降が誘発される事が報告されている(6)).このようにHiの脳室内投与が,動物の行動,体温,血圧等に影響を与える事は知られているが,Hiが鎮痛効果を誘発し得るか否かについて検討された報告は見当らない.Hiをヒトに静注すると,搏動性の頭痛が誘発され(7)),皮内注射では局所の疼痛を惹起する事(8))が知られている.しかし, Sanuki(9))は,マウスにHiの大量を皮下注射したところ,鎮痛効果がみられたと報告している.Hiをマウスの末梢側に非経口投与した際発現する種々な中枢作用には,脳内にとりこまれたHiが関与している可能性が報告されている(10,11))ので,Sanukiの実験でも末梢側に投与された大量のHiの一部が中枢神経系に移行し,鎮痛効果を発現している可能性は否定できない.著者はマウス脳内にHiを投与した際,鎮痛効果と可成り密接に相関すると考えられる仮性疼痛反応に対するHiの効果を調べると共に,morphineやその関連物質の前処置がHiの効果をいかに修飾するのかを調べ,Hi鎮痛効果発現の機序についても検討した.また,Hiの鎮痛効果がH(1)またはH(2)-receptorのいずれとより密接に相関するのかについての検討も併せて行なった.
en-copyright=
kn-copyright=

en-aut-name=OkadaIkuo
en-aut-sei=Okada
en-aut-mei=Ikuo
kn-aut-name=岡田郁男
kn-aut-sei=岡田
kn-aut-mei=郁男
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学歯学部口腔外科学教室
en-keyword=ヒスタミン
kn-keyword=ヒスタミン
en-keyword=鎮痛作用
kn-keyword=鎮痛作用
en-keyword=脳内投与
kn-keyword=脳内投与
en-keyword=モルヒネ
kn-keyword=モルヒネ
en-keyword=抗ヒスタミン剤
kn-keyword=抗ヒスタミン剤
END

start-ver=1.4
cd-journal=joma
no-vol=94
cd-vols=
no-issue=5-6
article-no=
start-page=405
end-page=421
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1982
dt-pub=19820630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Epileptogenic action of cephalosporins in rats and its structure-activity relationship. Part 1.
kn-title=Cephalosporin系抗生物質の痙攣誘発作用について 第1報 Cephalosporin系抗生物質の脳室内投与による痙攣誘発作用とその構造ー活性相関
en-subtitle=
kn-subtitle=
en-abstract=Stainless-steel electrodes were implanted stereotaxically into the hippocampus and amygdala and screw electrodes were fixed in the frontal and accipital skull of male Wistar rats. A cannula guide was also implanted in the right lateral ventricle. Ten days after operation, unanesthetized rats were placed in an observation box and electroencephalograms were recorded before and after intraventricular injection of the test drugs. Behavioral changes were observed simultaneously. When the epileptogenic properties of 10 cephalosporins and penicillin G as the refefence drugs were compared, cefazolin was definitely more potent than penicillin. At doses higher than 32 μg/head, cefazolin provoked tremendous epileptiform activity; "spike and wave complex" appeared in close session in all tracings for more than 30 min and svere convusion were observed with this repeatedly. Cefotiam was a little bit stronger than penicillin; both ceftezole and cephaloridine were almost equipotent and their activities were slightly weaker than penicillin. No epileptogenic signs or behavious was observed in the EEGs after 1000 μg/head of cephalexin and cephradine. Cephapirin, cefmetazole, cephalothin and ceftizoxime caused some epileptogenic symptoms but less markedly, diminishing the activity in this order both in EEGs and the behavioral signs between active and inert drugs. The compounds with two different heterocyclic rings substituted at position 7 of the beta-lactam ring and at position 3 of the dihydrothiazine ring (R2) of 7-aminocephalosporanic acid were potent in producing epileptogenic signs both in EEGs and behaviors. While the compounds with a heterocyclic ring substituted at either position of 7-amino-cephalosporanic acid were less potent. The compounds such as cefizoxime, cephalexin and cephradine which had a small group substituted at R2 produced almost no epileptogenic activity.
kn-abstract=Newton and Abraham(1))により見い出されたcephalosporin Cが,現在のcephalosporin系抗生物質のprototypeである.この薬物は, penicillinやchloramphenicolに比較するとその抗菌力は必ずしも強くないが,広域な抗菌スペクトルを有し,penicillinaseに比較的抵抗し得る事が特長であった.その化学構造は,penicillin Gに類似したβ-lactam環を有する7-amino-cephalosporanic acidを基本骨格としている事が明らかとなり,この骨格に種々な側鎖を結合する事により,抗菌力,安定性のより優れた半合成の類似化合物が多数作られた.これらの半合成cephalosporin系抗生物質は,グラム陽性球菌,グラム陰性球菌,グラム陽性桿菌及び一部のグラム陰性桿菌に対し殺菌的に作用し,しかも抗菌作用も強く,またpenicillinに対し耐性を獲得した梅毒トレポネーマやブドウ球菌に対しても有効(2))であるため,広く臨床で使用されている.口腔外科領域においても,これらのcephalosporin系抗生物質の静脈内投与や点滴静注が繁用されており,しかも投与量は時に数gの大量に達する.一方,penicillin Gの静脈内投与後に痙攣が誘発されたという報告(3,4))があり,また,penicillin Gの大脳皮質内適用後誘発される痙攣は,抗痙攣薬の薬効評価に用いられている程周知である(5,6)).penicillin Gによる痙攣誘発作用は,その構造内のβ-lactam環が関与すると考えられている(7,8)).もし,この説が正しければ,その構造式にβ-lactam環をもっているcephalosporin系抗生物質も当然penicillinと同様な痙攣誘発作用をもつ可能性がある.この仮説の当否を調べ,且つ種々な化学構造をもつcephalosporin系抗生物質の痙攣誘発効果の強弱が,それらの化学構造とどのような相関を示すのかを検討する目的で本実験を行なった.
en-copyright=
kn-copyright=

en-aut-name=IkegamiNobuyuki
en-aut-sei=Ikegami
en-aut-mei=Nobuyuki
kn-aut-name=池上信行
kn-aut-sei=池上
kn-aut-mei=信行
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学歯学部口腔外科学教室
en-keyword=Cephalosporin系抗生物質
kn-keyword=Cephalosporin系抗生物質
en-keyword=痙攣誘発効果
kn-keyword=痙攣誘発効果
en-keyword=脳波
kn-keyword=脳波
en-keyword=行動
kn-keyword=行動
en-keyword=構造ー活性相関
kn-keyword=構造ー活性相関
END

start-ver=1.4
cd-journal=joma
no-vol=96
cd-vols=
no-issue=3-4
article-no=
start-page=377
end-page=384
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1984
dt-pub=19840430
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the applicability of enterococci and coli-form groups as indicators of water pollution
kn-title=腸球菌および糞便性大腸菌の水質汚染指標性に関する検討
en-subtitle=
kn-subtitle=
en-abstract=The applicability of using enterococci and coli-form groups as indicators of water pollution was assessed. In human feces, enterococci were 10 times more numerous than coli-forms. Suspension of feces in sterile 0.85% NaCl solution at 25℃ did not result in enterococci growth. Coli-form groups, however, grew remarkably well. Enterococci were incapable of growth and died in filtration-sterilized river water. On the contrary, coli-form groups demonstrated significant growth. Tre pathogeneic enterobacteria (Sal. typhi, Sh. sonnei) died within four days, faster than enterococci. A 50-case field sample presented a correlation coefficient of +0.71 between the number of enterococci and coli-form groups. This indicated that enterococci and coli-form groups both serve as indicators of fecal water pollution. Enterococci numbered 2.3 times more than coli-forms. Coli-form group detection was not suitable for routine work, as it requires incubation at 45.5℃. These results indicate that enterococci are applicable for the indication of water pollution and more available than coli-form groups.
kn-abstract=腸球菌および糞便性大腸菌の水質汚染指標性の検討を行ない次のようなことが判明した.○人糞便中に腸球菌は糞便性大腸菌の約10倍多く存在していた.○糞便水を25℃におくと糞便性大腸菌は増殖したが,腸球菌は増殖しなかった.○メンブランフィルター濾過滅菌河川水中でE. coliは微小濃度の栄養源を利用しているものと考えられる増殖を示した.一方,消化器系 病原菌(Sal. typhi, Sh. sonnei)は4日程度ですみやかに死滅するが,腸球菌はそれよりやや遅く死滅する良好な生残性を示した.○野外調査を行ない河川水から腸球菌・糞便性大腸菌の検出を行なった結果, 50例による両者の相関係数は+0.71で糞便汚染指標菌として相関性があることが示され,量的には腸球菌が糞便性大腸菌の2.3倍多く検出された.○検査における手技の簡便性を考察すると糞便性大腸菌の検出は培養温度(44.5℃)の管理がわずらわしく,ルチンとしては不向きであると考えられた.以上のことから腸球菌は糞便性大腸菌よりも公共用水の汚染指標として有用であると結論された.
en-copyright=
kn-copyright=

en-aut-name=KoujimaIzumi
en-aut-sei=Koujima
en-aut-mei=Izumi
kn-aut-name=国府島泉
kn-aut-sei=国府島
kn-aut-mei=泉
aut-affil-num=1
ORCID=

en-aut-name=KanataniTomohisa
en-aut-sei=Kanatani
en-aut-mei=Tomohisa
kn-aut-name=金谷誠久
kn-aut-sei=金谷
kn-aut-mei=誠久
aut-affil-num=2
ORCID=

en-aut-name=KumodeAkira
en-aut-sei=Kumode
en-aut-mei=Akira
kn-aut-name=口分田晃
kn-aut-sei=口分田
kn-aut-mei=晃
aut-affil-num=3
ORCID=

en-aut-name=NodaYasuko
en-aut-sei=Noda
en-aut-mei=Yasuko
kn-aut-name=野田泰子
kn-aut-sei=野田
kn-aut-mei=泰子
aut-affil-num=4
ORCID=

en-aut-name=FukuharaAkihiro
en-aut-sei=Fukuhara
en-aut-mei=Akihiro
kn-aut-name=福原明宏
kn-aut-sei=福原
kn-aut-mei=明宏
aut-affil-num=5
ORCID=

en-aut-name=MoriNoriko
en-aut-sei=Mori
en-aut-mei=Noriko
kn-aut-name=森徳子
kn-aut-sei=森
kn-aut-mei=徳子
aut-affil-num=6
ORCID=

en-aut-name=KanemasaYasuhiro
en-aut-sei=Kanemasa
en-aut-mei=Yasuhiro
kn-aut-name=金政泰弘
kn-aut-sei=金政
kn-aut-mei=泰弘
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部細菌学教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部細菌学教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部細菌学教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部細菌学教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部細菌学教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部細菌学教室

affil-num=7
en-affil=
kn-affil=岡山大学医学部細菌学教室
en-keyword=Enterococcus
kn-keyword=Enterococcus
en-keyword=Fecal coli-form
kn-keyword=Fecal coli-form
en-keyword=Water pollution
kn-keyword=Water pollution
en-keyword=Biological indicator
kn-keyword=Biological indicator
END

start-ver=1.4
cd-journal=joma
no-vol=98
cd-vols=
no-issue=11-12
article-no=
start-page=1007
end-page=1016
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1986
dt-pub=19861230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on vitamin E and lipoperoxide in stroke Part I. Changes in serum α-tocopherol and lipoperoxide levels in the acute stage of stroke
kn-title=脳卒中におけるビタミンEと過酸化脂質 第1編 脳卒中における血清ビタミンE,過酸化脂質の経時的変動
en-subtitle=
kn-subtitle=
en-abstract=Serum levels of α-tocopherol (α-Toc), lipoperoxide (TBARS) and lipids were studied in the acute stage of stroke. Serum α-Toc was 0.74±0.32mg/dl (n=67) within 48 hours of the onset of stroke, which was significantly lower than the level of the control group (0.99±0.22mg/dl). Concurrently, serum TBARS was 6.04±2.17 nmol/ml (n=57) which was markedly higher than the level of the control group (3.22±0.89 nmol/ml). No correlation was seen in serum α-Toc and TBARS. However, serum total cholesterol (TC) correlated with α-Toc in stroke. Serum α-Toc of most cases of stroke dropped to the lowest level in the first 5 to 6 days and thereafter recovered gradually. The ratio of a-Toc to TC in serum reached a minimum in the early phase and then rose gradually over two weeks. Serum TBARS increased during the first week, and thereafter decreased slowly. These results imply that α-Toc may be consumed as an antioxidant against lipoperoxide which presumably increases depending on tissue damage induced by stroke.
kn-abstract=脳卒中や心筋梗塞をはじめとする動脈硬化性病変の発生や進展に過酸化脂質が関与していることが最近注目されてきたが,これは1952年にGlavindら1)が大動脈粥状硬化巣に過酸化脂質の存在を証明し,粥状硬化の程度と過酸化脂質の量との間に相関があるとした報告に端を発している.過酸化脂質は高度不飽和脂肪酸が,酸素と直接結合したもので,強い反応性を持つため酵素やビタミンを失活させ,蛋白や生体膜を変性させ,その結果として,細胞機能に障害を及ぼし,老化や動脈硬化と関連しているとされている2〜4).一方,生体には過酸化脂質生成を制御している種々の機構も存在し,superoxide dismutaseあるいはビタミンE,還元グルタチオンなどのようないわゆるfree radical scavengerや抗酸化剤がその役割をはたしている.著者はその中で抗酸化剤であるビタミンEに注目し,代表的血管障害である脳卒中において,発症後より経時的に血清ビタミンE,過酸化脂質,血清脂質を測定し,ビタミンEの動態を過酸化脂質との関連において検討した.
en-copyright=
kn-copyright=

en-aut-name=ShojiKojiro
en-aut-sei=Shoji
en-aut-mei=Kojiro
kn-aut-name=正路浩二郎
kn-aut-sei=正路
kn-aut-mei=浩二郎
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学第2内科
en-keyword=α-tocopherol
kn-keyword=α-tocopherol
en-keyword=lipoperoxide
kn-keyword=lipoperoxide
en-keyword=TBARS
kn-keyword=TBARS
en-keyword=脳卒中
kn-keyword=脳卒中
END

start-ver=1.4
cd-journal=joma
no-vol=95
cd-vols=
no-issue=5-6
article-no=
start-page=437
end-page=447
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1983
dt-pub=19830630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Oxidative phosphorylation of mitochondria in digitonin-treated permeable ascites sarcoma cells
kn-title=ジギトニン処理permeable腹水肉腫細胞におけるミトコンドリアの酸化的リン酸化
en-subtitle=
kn-subtitle=
en-abstract=Substrate-permeable cells were prepared by treatment of Rous Sarcoma virus-induced mouse ascites sarcoma cells (SR-C3H/He) with a low concentration of digitonin. Using relatively small amounts of the digitonin-treated permeable cells, mitochondrial functions such as a respiratory rate, respiratory control ratio (RCR), and ADP/O ratio of oxidative phosphorylation were easily measured by the oxygen electrode method. The permeable ascites sarcoma cell mitochondria had a slightly lower RCR and ADP/O ratio than mitochondria isolated from mouse liver and ascites sarcoma cells. This result was found to be mainly due to higher extramitochondrial Mg(2+)-ATPase activity in the permeable ascites sarcoma cells. The effects of hexokinase and pyruvate kinase on the RCR and the ADP/O ratio were investigated by the additions of glucose and phosphoenolpyruvate as substrates, but these enzymes can not be the main factors in decreasing the RCR and the ADP/O ratio in the permeable ascites sarcoma cells since the glycolytic pathway was not continuous in these cells. The digitonin-treated permeable cell system is an extremely useful system for studying mitochondrial functions and their relations to other organelae and metabolic pathways under near in vivo conditions.
kn-abstract=ラウス肉腫ウィルス誘発腹水肉腫細胞(SR-C3H/He)を低濃度のジギトニン(終末0.01%)で処理し,基質透過性細胞とすることにより,少量の材料で簡単にミトコンドリアの呼吸速度,呼吸調節率(RCR),酸化的リン酸化能(ADP/0 比)などの機能を酸素電極法を用いて調べられることがわかった.この基質透過性腹水肉腫細胞ではマウス肝や腹水肉腫細胞から分離したミトコンドリアより,呼吸調節率や酸化的リン酸化能が幾分低い.この原因について種々なATPase活性を検討した結果,この透過性細胞では主にミトコンドリア以外のMg(2+)-ATPase活性がかなり高く存在し,これによって呼吸調節率や酸化的リン酸化能の低下が生じることが示唆された.また,この透過性細胞に解糖系の基質であるグルコースやホスホエノールピルビン酸を添加しhexokinaseやpyruvate kinaseの存在による呼吸調節への影響を認めたが,解糖系の一連の反応は不連続であり,呼吸調節率や酸化的リン酸化能の低下の主因であるとは考え難い.このように,低濃度のジギトニン処理透過性細胞は比較的少量のwhole cellでのミトコンドリアの酸化的リン酸化と呼吸阻害剤や脱共役剤の影響を簡便に調べることができ,さらに細胞内オルガネラの機能と代謝系の相関をin vivoに近い条件下で調べることのできるきわめて有用な実験系であると考えられる.
en-copyright=
kn-copyright=

en-aut-name=ShigeharaTsuguya
en-aut-sei=Shigehara
en-aut-mei=Tsuguya
kn-aut-name=茂原嗣也
kn-aut-sei=茂原
kn-aut-mei=嗣也
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部癌源研究施設生化学部
en-keyword=ミトコンドリア
kn-keyword=ミトコンドリア
en-keyword=透過性細胞
kn-keyword=透過性細胞
en-keyword=酸化的リン酸化
kn-keyword=酸化的リン酸化
en-keyword=ATPase
kn-keyword=ATPase
en-keyword=ジギトニン
kn-keyword=ジギトニン
END

start-ver=1.4
cd-journal=joma
no-vol=99
cd-vols=
no-issue=7-8
article-no=
start-page=955
end-page=969
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=19870830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the Pathogenesis of Duodenal Ulcer from the Viewpoint of the Gastro-Pancreatic Secretory Relationship.2. Gastric Juice Secretion and Pure Pancreatic Juice Secretion in Response to Intraduodenal Acid Load.
kn-title=胃膵分泌相関からみた十二指腸潰瘍の発生病理　第2編　胃酸分泌および内因性刺激に対する純粋膵液の分泌動態
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=To delineate stomach-pancreas interactions as related to the pathogenesis of duodenal ulcer, a comparison of gastric secretory function and exocrine pancreatic secretory function was made in controls, patients with gastric ulcer and those with duodenal ulcer. Gastric juice was aspirated through a Rehfuss tube before and after an injection of AOC-tetragastrin (4 μg/kg of body weight). Exocrine pancreatic function was determined by measuring the initial HCO(3) concentration (wash-out phase), HCO(3) output and maximal HCO(3) concentration of pure pancreatic juice collected endoscopically after intraduodenal instillation of hydrochloric acid (0.1 N, 100 ml). Serum secretin was also measured serially. Patients with duodenal ulcer showed significantly higher gastric acid secretion. They also showed significantly higher pancreatic HCO(3) output as well as higher initial HCO(3)　concentration as in my previous study on exogenous secretin stimulation. A significant correlation was noted between gastric acid secretion and pancreatic HCO(3) secretion. However, the serum secretin response did not differ significantly among the three groups. These results indicate that patients with duodenal ulcer display a normal secretin release response to intraduodenal acid load and an augmented pancreatic bicarbobate secretion in response to the released secretin. These findings were discussed in relation to the pathogenesis of duodenal ulcer.
en-copyright=
kn-copyright=

en-aut-name=HanafusaEiji
en-aut-sei=Hanafusa
en-aut-mei=Eiji
kn-aut-name=花房英二
kn-aut-sei=花房
kn-aut-mei=英二
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第二内科教室
en-keyword=胃膵分泌相関
kn-keyword=胃膵分泌相関
en-keyword=十二指腸潰瘍
kn-keyword=十二指腸潰瘍
en-keyword=純粋膵液
kn-keyword=純粋膵液
en-keyword=胃液分泌
kn-keyword=胃液分泌
en-keyword=膵外分泌
kn-keyword=膵外分泌
END

start-ver=1.4
cd-journal=joma
no-vol=99
cd-vols=
no-issue=7-8
article-no=
start-page=943
end-page=954
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=19870830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the Pathogenesis of Duodenal Ulcer from the Viewpoint of the Gastro-Pancreatic Secretory Relationship. 1. Gastric and Pure Pancreatic Juice Secretion in Response to Exogenous Hormone Stimulation.
kn-title=胃膵分泌相関からみた十二指腸潰瘍の発生病理　第1編　外因性刺激に対する胃液および純粋膵液の分泌動態
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Comparative studies on gastric secretory function and exocrine pancreatic secretory function were made in 9 normal controls, 6 patients with gastric ulcer and 10 patients with duodenal ulcer by analysis of gastric juice and pure pancreatic juice (PPJ). Gastric juice was obtained through a Rehfuss tube at 10-minute intervals for 60 minutes before and after AOC-tetra-gastrin stimulation (4 μg/kg). PPJ was obtained by endoscopic retrograde catheterization of the papilla at one-minute intervals for 20 minutes after a bolus intravenous injection of secretin (Eisai, 1 U/kg) and for 10 minutes after an injection of CCK-PZ (Boots, 1 U/kg). Patients with duodenal ulcer had significantly high basal acid output (BAO) and maximal acid output (MAO), a significantly high bicarbonate concentration in the initial fraction of PPJ, and significantly high bicarbonate output during the secretin phase. A significant correlation was noted between the bicarbonate concentration in the initial fraction of the PPJ and the BAO and MAO, and also between the bicarbonate output and the BAO and MAO. These results indicate that bicarbonate secretion of the pancreas in response to secretin is proportionally raised in patients with duodenal ulcer to neutralize the raised gastric acid secretion. These findings were discussed in relation to the pathogenesis of duodenal ulcer.
en-copyright=
kn-copyright=

en-aut-name=HanafusaEiji
en-aut-sei=Hanafusa
en-aut-mei=Eiji
kn-aut-name=花房英二
kn-aut-sei=花房
kn-aut-mei=英二
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第2内科教室
en-keyword=胃膵分泌相関
kn-keyword=胃膵分泌相関
en-keyword=十二指腸潰瘍
kn-keyword=十二指腸潰瘍
en-keyword=純粋膵液
kn-keyword=純粋膵液
en-keyword=胃液分泌
kn-keyword=胃液分泌
en-keyword=膵外分泌
kn-keyword=膵外分泌
END

start-ver=1.4
cd-journal=joma
no-vol=63
cd-vols=
no-issue=
article-no=
start-page=134
end-page=141
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199206
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=抗原および抗ヒトIgEに対する抗塩基球の反応性. 3.Ca2(+)の細胞内流入およびヒスタミン遊離
kn-title=Basophil response to antigen and anti-IgE 3. Ca(2+) influx and histamine release
en-subtitle=
kn-subtitle=
en-abstract=ハウスダスト,カンジダなどの抗原および抗ヒトIgE刺激時の,抗塩基球および肥満細胞からの化学伝達物質遊離機序について,若干の検討を行った｡1.肥満細胞へのCa(2+)の流入は,抗原刺激後に増加する傾向を示した｡この肥満細胞のCa(2+)取り込みの増加は,抗アレルギー剤であるクロモリン(DSCG)やトラニラストやCa(2+)拮抗剤であるニフェジピンやニカルジピンによって抑制された｡2.抗原(ハウスダスト)によるヒスタミン遊離の濃度依存性カーブは,抗ヒトIgEによるカーブとは異なっていた｡しかし,ハウスダストが抗原である症例では,抗原による最高ヒスタミン遊離値は,抗ヒトIgEによる遊離値とある程度の相関を示した｡そして,抗原(ハウスダスト)および抗ヒトIgEによる好塩基球からのヒスタミン遊離は,血清IgE値が上昇するにつれて,増加する傾向が見られた｡一方,カンジダによるヒスタミン遊離は,血清IgE値との相関は無く,また,抗ヒトIgEによるヒスタミン遊離との間にも関連は見られなかった。
kn-abstract=The release mechanism of chemical mediators from basophils and mast cells was discussed when these cells were stimulated by different antigens and anti-IgE. 1. Ca(2+) influx into mast cells increased after stimulation by antigen. The increased Ca(2+) uptake by mast cells was inhibited by antiallergic agents, disodium cromoglycate (DSCG) and tranilast, and calcium antagonists, nifedipine and nicardipine. 2. The dose-response curve of histamine release by antigen was different from that by anti-IgE. The maximum release of histamine by house dust was, however, similar to that by anti-IgE. House dust- and anti-IgE-induced release of histamine increased with higher- serum IgE levels. On the contrary, the release of histamine by Candida albicans was not releated to serum IgE levels, and the release by C. albicans did not parallel therelease by anti-IgE.
en-copyright=
kn-copyright=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=1
ORCID=

en-aut-name=KitaniHikaru
en-aut-sei=Kitani
en-aut-mei=Hikaru
kn-aut-name=貴谷光
kn-aut-sei=貴谷
kn-aut-mei=光
aut-affil-num=2
ORCID=

en-aut-name=OkazakiMorihiro
en-aut-sei=Okazaki
en-aut-mei=Morihiro
kn-aut-name=岡崎守宏
kn-aut-sei=岡崎
kn-aut-mei=守宏
aut-affil-num=3
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=4
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=5
ORCID=

en-aut-name=KimuraIkuro
en-aut-sei=Kimura
en-aut-mei=Ikuro
kn-aut-name=木村郁郎
kn-aut-sei=木村
kn-aut-mei=郁郎
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院

affil-num=6
en-affil=
kn-affil=岡山大学医学部第二内科
en-keyword=Ca(2+) influx (Ca2+流入)
kn-keyword=Ca(2+) influx (Ca2+流入)
en-keyword=histamine release (ヒスタミン遊離)
kn-keyword=histamine release (ヒスタミン遊離)
en-keyword=house dust (ハウスダスト)
kn-keyword=house dust (ハウスダスト)
en-keyword=Candida albicans (カンジダ)
kn-keyword=Candida albicans (カンジダ)
en-keyword=anti-lgE (抗ヒトIgE)
kn-keyword=anti-lgE (抗ヒトIgE)
END

start-ver=1.4
cd-journal=joma
no-vol=63
cd-vols=
no-issue=
article-no=
start-page=106
end-page=109
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199206
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Physical therapy of patients with total hysterectomy
kn-title=子宮全摘術後患者における理学療法 ―自転車エルゴメーター負荷による心拍数の変化について―
en-subtitle=
kn-subtitle=
en-abstract=Twenty-one patients with total hysterectomy had a physical therapy program, including swimming training in a hot spring pool, muscle stretching and muscle strengthening
exercise. Effects of this program were evaluated by bicycle ergometric challenge test. Maximum increased heart rate of the patients on the ergometric challenge test was significantly lower after the end of the program compared with the initial value before program (p<0.02). However, the effects of such physical therapy program on heart rate did not correlate with the frequency of the program. All patients were able to return to social work without any difficulties. These results support the efficacy of the physical therapy program in our hospital.
kn-abstract=子宮全摘術を受け,回復期に理学療法を実施した患者に,自転車エルゴメーターによる同一負荷運動時の心拍数について施行前と退院時の変化を検討した｡その結果,退院時に心拍数は有意に減少した｡しかし,その減少の程度は理学療法実施回数と相関しなかった｡患者は水中運動を積極的に実施し,速やかに家庭生活を含めた社会生活への復帰が可能となった｡退院後の外来診察時に異常も認められず,理学療法の有効性並びに安全性が確認された。
en-copyright=
kn-copyright=

en-aut-name=KamimotoManabu
en-aut-sei=Kamimoto
en-aut-mei=Manabu
kn-aut-name=上本学
kn-aut-sei=上本
kn-aut-mei=学
aut-affil-num=1
ORCID=

en-aut-name=OkudaHiroyuki
en-aut-sei=Okuda
en-aut-mei=Hiroyuki
kn-aut-name=奥田博之
kn-aut-sei=奥田
kn-aut-mei=博之
aut-affil-num=2
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院リハビリテーション部

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院産婦人科

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科
en-keyword=子宮全摘術 (Abdominal hysterectomy)
kn-keyword=子宮全摘術 (Abdominal hysterectomy)
en-keyword=術後理学療法 (Postoperative Physical therapy)
kn-keyword=術後理学療法 (Postoperative Physical therapy)
en-keyword=自転車エルゴメーター (Bicycle ergometer)
kn-keyword=自転車エルゴメーター (Bicycle ergometer)
en-keyword=心拍数 (Heart rate)
kn-keyword=心拍数 (Heart rate)
END

start-ver=1.4
cd-journal=joma
no-vol=63
cd-vols=
no-issue=
article-no=
start-page=99
end-page=105
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199206
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Relationship between bone mineral densities　of second metacarpal bone and lumber spine
kn-title=手指骨骨塩量と腰椎骨塩量の相関性と診断への応用
en-subtitle=
kn-subtitle=
en-abstract=To compare bone mineral density between second metacarpal bone and lumber spine,　two measuring methods, digital image processing　method (DIP) for second metacarpal bone and quantitative computed tomography (QCT) for lumber spine were employed in this study. The bone mineral density was evaluated in 89 females and the results were
compared between the two methods. A correlation between the bone mineral densities by QCT and ΣGS/D was found in subjects showing low mineral density by QCT, but not in those with high mineral density. These results reveal that DIP is useful to observe bone mineral density and if ΣGS/D and MCI are enough high, almost he hasn't risk of fracture of lumber spine.
kn-abstract=QCTおよびDIP法による測定値の相関性について検討し,DIP法による腰椎骨塩量の推定および,スクリーニングへの適用について考察した｡QCT値とΣGS/DやMClとの相関関係の検討では.対象のQCT値が低値か高値かによって相関関係がかなり異なることが明らかになった｡すなわち,QCT値が低い領域は,QCT値と,ΣGS/DやMCIに明らかな正の相関関係が認められたが,一方,
QCT値が高い領域では,相関関係は認められなかった｡また,ΣGS/D=2.8mmAI以上,またはMCI=0.48以上の症例においては腰椎圧迫骨折の危険は小さく,ΣGS/D=1.8mmAI以下,またはMCI=0.24以下の症例においては腰椎圧迫骨折の危険が大きい可能性が示唆された。
en-copyright=
kn-copyright=

en-aut-name=NakaiMutsuo
en-aut-sei=Nakai
en-aut-mei=Mutsuo
kn-aut-name=中井睦郎
kn-aut-sei=中井
kn-aut-mei=睦郎
aut-affil-num=1
ORCID=

en-aut-name=OkudaHiroyuki
en-aut-sei=Okuda
en-aut-mei=Hiroyuki
kn-aut-name=奥田博之
kn-aut-sei=奥田
kn-aut-mei=博之
aut-affil-num=2
ORCID=

en-aut-name=AkiyamaTsuneo
en-aut-sei=Akiyama
en-aut-mei=Tsuneo
kn-aut-name=穐山恒雄
kn-aut-sei=穐山
kn-aut-mei=恒雄
aut-affil-num=3
ORCID=

en-aut-name=TakatoriAkimasa
en-aut-sei=Takatori
en-aut-mei=Akimasa
kn-aut-name=高取明正
kn-aut-sei=高取
kn-aut-mei=明正
aut-affil-num=4
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=5
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院放射線室

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院産科婦人科

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院放射線室

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院産科婦人科

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科
en-keyword=骨粗鬆症 (osteoporosis)
kn-keyword=骨粗鬆症 (osteoporosis)
en-keyword=骨塩量 (bone mineral density)
kn-keyword=骨塩量 (bone mineral density)
en-keyword=QCT (quantitative computed tomography)
kn-keyword=QCT (quantitative computed tomography)
en-keyword=DIP法 (digital image processing method)
kn-keyword=DIP法 (digital image processing method)
END

start-ver=1.4
cd-journal=joma
no-vol=7
cd-vols=
no-issue=2
article-no=
start-page=99
end-page=103
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1997
dt-pub=19970131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=変形性膝関節炎患者膝関節液中の細胞外マトリックス成分と可溶性VCAM-1
kn-title=Extracellular matrix components and soluble VCAM-1 in synovial fluid with osteoarthritis of the knee
en-subtitle=
kn-subtitle=
en-abstract=変形性膝関節炎(OA)患者は,高齢化社会の到来とともに今後ますます増加するものと考えられる｡OAの発症メカニズムについては,関節軟骨の破壊･修復やパンヌス形成に関わる多くの関連因子(サイトカイン,マトリックス分解酵素,分解酵素抑制因子,プロテオグリカン,活性酸素,細胞接着因子など)について,多面的に研究が進んでいる｡しかし,膝関節の炎症初期の病態のメカニズムについては,なお詳細に解明されておらず,関節炎初期の炎症指標の検索が今後さらに必要と考えられる｡本研究で私たちは, OA患者膝関節液中の細胞外マトリックス構成成分であるコラーゲン,へパラン硫酸プロテオグリカン,ウロン酸および炎症の最も初期に血管内皮細胞に出現するVCAM-1等の可溶化成分濃度を測定した｡患者膝関節液(SF)中の可溶性コラーゲン量と可溶性VCAM-1(sVCAM-1)量とは有意な正の相関関係が(ρ=0.652)観察された｡しかし,ヘパラン硫酸プロテオグリカン(HSPG)と可溶性コラーゲン(sCOLL)値間には有意な相関関係は確認されなかった｡また,一般に炎症の指標として用いられるCRP値とも比戟検討したが,CRP値と他の測定項目値とは一定の相関関係は存在しなかった。以上の結果より,OA患者のSF中の炎症マーカ-として,急性炎症時には従来の炎症指標蛋白質であるCRP値が有力であるというSipe JDの報告から推測するとsCOLLとsVCAM-1はCRP値と一定の相関を示さないことより,CRPの動態とは異なった炎症指標としての有用性が考えられる｡しかし,HSPGはエンドサイトシスにより速やかに代謝されるためSF中への解離が少なく,炎症指標としての可能性は低いと考えられる｡
kn-abstract=It is generally accepted that the number of patients with osteoarthritis (OA) of the knee must increase in the future because of the increase of the aged. The pathogenic mechanisms of OA haven't been elucidated yet, but it is supposed that mediate pannus may cause the factors for irreversible cartilage damage in the inflammatory process. Therefore it is very important to find and predict OA at the early stage. Now there were many indices to determine joint damage with OA, for example, cytokines including IL, TNF, TGF, matrix metalloproteinase (MMPs), tissue inhibitor of metalloproteinase (TIMPs), proteoglycan (PG), hyaluronate (HA), super oxide, adhesion molecules including, ICAM-1, VCAM-1 and PECAM. In this study, we measured that the soluble VCAM-1 (sVCAM-1), soluble collagen (sCOLL), heparansulfate proteoglycan (HSPG), uronic acis and CRP in synovial fluids (SF) with OA. A positive correlation between the level of sVCAM-1 and sCOLL (ρ = 0.652) was noted. However there was no factor showing a correlation with CRP. It was suggested that the levels of sVCAM-1 and sCOLL in the synovia fluid were active inflammation indices of knee damage, as the different aspects from CRP. The level of HSPG also showed a unique trend because HSPG on the cell surface was quickly digested endocytosis, so that it was not suitable for the inflammatory index in synovial fluid with OA.
en-copyright=
kn-copyright=

en-aut-name=TohgeHiroko
en-aut-sei=Tohge
en-aut-mei=Hiroko
kn-aut-name=唐下博子
kn-aut-sei=唐下
kn-aut-mei=博子
aut-affil-num=1
ORCID=

en-aut-name=IchimuraMitsuko
en-aut-sei=Ichimura
en-aut-mei=Mitsuko
kn-aut-name=一村光子
kn-aut-sei=一村
kn-aut-mei=光子
aut-affil-num=2
ORCID=

en-aut-name=SakiyamaJunko
en-aut-sei=Sakiyama
en-aut-mei=Junko
kn-aut-name=崎山順子
kn-aut-sei=崎山
kn-aut-mei=順子
aut-affil-num=3
ORCID=

en-aut-name=OkamotoMotoi
en-aut-sei=Okamoto
en-aut-mei=Motoi
kn-aut-name=岡本基
kn-aut-sei=岡本
kn-aut-mei=基
aut-affil-num=4
ORCID=

en-aut-name=NakataYasunari
en-aut-sei=Nakata
en-aut-mei=Yasunari
kn-aut-name=中田安成
kn-aut-sei=中田
kn-aut-mei=安成
aut-affil-num=5
ORCID=

en-aut-name=EndoHiroshi
en-aut-sei=Endo
en-aut-mei=Hiroshi
kn-aut-name=遠藤浩
kn-aut-sei=遠藤
kn-aut-mei=浩
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医療技術短期大学部衛生技術学科

affil-num=2
en-affil=
kn-affil=岡山大学医療技術短期大学部衛生技術学科

affil-num=3
en-affil=
kn-affil=岡山大学医療技術短期大学部衛生技術学科

affil-num=4
en-affil=
kn-affil=岡山大学医療技術短期大学部衛生技術学科

affil-num=5
en-affil=
kn-affil=岡山大学医療技術短期大学部衛生技術学科

affil-num=6
en-affil=
kn-affil=岡山大学医療技術短期大学部衛生技術学科
en-keyword=変形性膝関節炎 (Osteoarthritis)
kn-keyword=変形性膝関節炎 (Osteoarthritis)
en-keyword=細胞外マトリックス (Extracellular matrix)
kn-keyword=細胞外マトリックス (Extracellular matrix)
en-keyword=可溶性VCAM-1 (Soluble VCAM-1)
kn-keyword=可溶性VCAM-1 (Soluble VCAM-1)
en-keyword=可溶性コラーゲン (Soluble Collagen)
kn-keyword=可溶性コラーゲン (Soluble Collagen)
en-keyword=可溶性ヘパラン硫酸プロテオグリカン (Soluble HSPG)
kn-keyword=可溶性ヘパラン硫酸プロテオグリカン (Soluble HSPG)
END

start-ver=1.4
cd-journal=joma
no-vol=8
cd-vols=
no-issue=1
article-no=
start-page=77
end-page=84
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1997
dt-pub=19970910
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Food intake and nutrients intake of nursing student.
kn-title=看護学生の食品摂取量と栄養摂取状況
en-subtitle=
kn-subtitle=
en-abstract=A questionnaire survey on daily food intake was conducted to assess the food intake,the nutritional intake and fulfilling rate of nutrients in 145 second-years students of School of Health Sciences, Okayama University, in 1993 and 1994. The following results were obtained. 1. The mean fulfilling rate was low for dietary fiber, while it was high for vitamin A and vitamin C. 2. There were low correlation between the number of foods and any specific nutrient. Intakes of energy,iron, Vitamin C and salt were significantly higher in students taking a large number of
foods than those taking a small number of foods. 3. There was a correlation between the intake of dietary fiber and that of vitamin A. Students with a low fulfilling rate of dietary fiber tended to have low fulfilling rate of calcium and iron. 4. There were no differences between students living with their parents and those living alone. Food intake should be decided effectively to correct nutritional imbalance in students. It is necessary to inform young people how to form dietary habits corresponding to their taste and life-style.
kn-abstract=1993年及び1994年度の本短期大学部看護学科の2年次生145名を対象に, 1日の摂取食品調査を行い,摂取食品数,栄養摂取量,栄養素等充足率を求めた。これらの分析の結果,以下の結論を得た。1.全体の平均充足率のバランスは,食物繊維が低く,ビタミンA,ビタミンCが高い値を示した。2.摂取食品数と栄養素等との相関は低かったが,食品数を2群に分けて比較すると,食品数多群でエネルギー,鉄,ビタミンC,食塩の摂取量が有意に多かった。3.充足率の低かった食物繊維とビタミンAは相関があり,また食物繊維の充足率の低い学生は,カルシウム,鉄の充足率が低い傾向にあった。4.自宅生と下宿生の比較では,差は見られなかった｡これらの改善には,栄養素等の不足を効果的に補える食品の選択や,若い世代の嗜好や生活にあった食習慣形成のための情報提供が必要である｡
en-copyright=
kn-copyright=

en-aut-name=HoshinaEiko
en-aut-sei=Hoshina
en-aut-mei=Eiko
kn-aut-name=保科英子
kn-aut-sei=保科
kn-aut-mei=英子
aut-affil-num=1
ORCID=

en-aut-name=OhtaNiwa
en-aut-sei=Ohta
en-aut-mei=Niwa
kn-aut-name=太田にわ
kn-aut-sei=太田
kn-aut-mei=にわ
aut-affil-num=2
ORCID=

en-aut-name=OhtaTakeo
en-aut-sei=Ohta
en-aut-mei=Takeo
kn-aut-name=太田武夫
kn-aut-sei=太田
kn-aut-mei=武夫
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医療技術短期大学部看護学科

affil-num=2
en-affil=
kn-affil=岡山大学医療技術短期大学部看護学科

affil-num=3
en-affil=
kn-affil=岡山大学医療技術短期大学部看護学科
en-keyword=看護学生 (nursing students)
kn-keyword=看護学生 (nursing students)
en-keyword=食品摂取量 (food intake)
kn-keyword=食品摂取量 (food intake)
en-keyword=栄養摂取量 (nutrients intake)
kn-keyword=栄養摂取量 (nutrients intake)
END

start-ver=1.4
cd-journal=joma
no-vol=8
cd-vols=
no-issue=1
article-no=
start-page=61
end-page=68
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1997
dt-pub=19970910
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The relationships between the components in QOL causal model of kidney posttransplant recipients and recipient characteristics.
kn-title=腎移植後レシピエントQOL因果モデルの構成要素とレシピエント特性との関係
en-subtitle=
kn-subtitle=
en-abstract=The purpose of this study is to analyze the relationships between the components in QOL causal model of kidney posttransplant recipients and recipients characteristics. Based on the conceptual framework for study, the QOL causal model was constructed. The subjects are 210 recipients after kidney transplant aged 20 or more from four hospitals in Kanto area and Nagoya city, who agreed
to participating in this study. The data were collected by means of an interview and a questionnaire, and from medical records. The questionnaire consists of physical state, self-concept, uncertainty, social support, coping, QOL, and medical and demographic characteristics such as age, marital status, education, time since transplant. Pearson's correlation coefficient, t-test, and one-way ANOVA were used for analysis. Age, job, marital status, education, time since transplant, frequency of hospitalization, and complications were related to any of the components of the causal model. From this evidence, it follows that they are important characteristics for the care of the recipients after kidney transplant.
kn-abstract=本研究の目的は,概念枠組みを基盤にして作成した腎移植後レシピエントQOL因果モデルの構成要素とレシピエント特性との関係を明らかにすることである｡対象者は,関東と名古屋の4施設において外来通院をしている腎移植者で,研究参加に同意を得た210名である。データ収集は,自己記入式質問紙
法,面接法ならびに診療記録より収集した。その内容は,身体の状態,自己概念,不確かさ,ソーシャルサポート,対処,QOLについてである｡またレシピエント特性として,年齢,婚姻状況,学歴,移植後年数などを取り上げた｡データ分析は,ピアソンの積率相関係数, t検定,一元配置分散分析(対比較)を用いた｡分析の結果,年齢,婚姻状況,学歴,就労状況,移植後年数,入院を要するほどの合併症および入院回数がモデルの構成要素のいずれかに関係していた｡
したがって,それらは腎移植後のケアを行う時に考慮されるべき重要なレシピエント特性であることが明らかになった｡
en-copyright=
kn-copyright=

en-aut-name=HayashiYuko
en-aut-sei=Hayashi
en-aut-mei=Yuko
kn-aut-name=林優子
kn-aut-sei=林
kn-aut-mei=優子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医療技術短期大学部看護学科
en-keyword=QOL (quality of life)
kn-keyword=QOL (quality of life)
en-keyword=対処 (coping)
kn-keyword=対処 (coping)
en-keyword=対処に影響を及ぼす要因 (affecting factors on the coping)
kn-keyword=対処に影響を及ぼす要因 (affecting factors on the coping)
en-keyword=レシピエント特性 (recipient characteristics)
kn-keyword=レシピエント特性 (recipient characteristics)
END

start-ver=1.4
cd-journal=joma
no-vol=9
cd-vols=
no-issue=2
article-no=
start-page=91
end-page=104
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990226
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A study on the correlation between the results of entrance examination and the academic record of the students in the department of laboratory technology
kn-title=衛生技術学科入学者の高校評点,入学試験成績と入学後の学業成績の関係 ―入学者選抜,教育方法の改善に向けた自己点検･評価(1)―
en-subtitle=
kn-subtitle=
en-abstract=The correlation between the school record in high school, result of entrance examination and the academic record, failure in promotion and withdrawal from school was examined in 361 students entered into department of laboratory technology from 1987 to 1995. 1) Thirty-nine students (10.8%) had failed in promotion, and 18 students (5%) had leaved from the school. The reason of withdrawal was refusal in 6 cases, and 4 students had changed their course to other universities. These cases were more frequent in the period until 1990 than in the period after 1991. 2) There were no differences in the school record in high school and the result of entrance examination among students who graduated scheduled period of attendance (regular students), those who failed in promotion, and those who had leaved the school. However, the students who
failed in promotion had got higher score in entrance examination than regular students in 1987 and 1988. In contrast, regular students had got higher score in entrance examination than the students failed in promotion in 1991 and 1993. 3) The school record in high school could be cheked during the period from 1991 to1995. In this
period, the students failed in promotion had got lower score in high school than regular students. Especially, the difference was significant in 1991 and 1993. 4) There was a significant positive correlation between the results in examination of general subjects and those in examination of technical and proffesional education. 5) The school records in high school had relatively weak positive correlation with the results of entrance examination. In contrast, both the school record in high school and result of entrance examination had clear positve correlations with both the results in examination of general subjects and technical and proffesional education. 6) However, the result of each subject of entrance examination, i.e. Japanese, Mathematics, English,
and Science, had no or weak positive correlation with both the results in examination of general subjects and technical and proffesional education. 7) The students who had not passed the national examination of laboratory technologist had lower score in school record in high school, entrance examination, examination of general subjects and technical and proffesional education, but the diffenreces were not statistically significant. The results of the study indicate that there were students who failed in promotion or leaved school despite their excellent ability during four years following the establishment of School of Health Sciences, but thereafter the ability of students gradually became homogeneous and increased the students who failed in promotion because of insufficient ability. The highly positive correlation
between the results in examination of general subjects and those in examination of technical and proffesional education indicate that the results of examination in the first year were directly reflected in the results of examination in second and third year, and that it is important to encourage the students's motivation and volition to study with ardor immediately after the entrance. The positive correlation of school record in high school and result of entrance examination with academic record after the entrance implicate the potential usefulness of school record in high school and result of entrance examination in determining the eligibility to enter the school. However, it is desirable to improve the subjects and problems of entrance examination because the result of each subject of entrance examination was poorly reflected in the academic record.
kn-abstract=1987年4月から1995年4月の9年間に衛生技術学科へ入学した361名を対象に,高校評点,入学試験(学力試験)成績と,入学後の学業成績,退学,留年,臨床検査技師国家試験との関係を調べた｡ 1)入学者総数は361名で,このうち留年者が39名(10,8%),退学者が18名(5%)であった｡退学者の中には,実質入学辞退者が6名,4年制大学へ進路を変更した者が4名いたが,こうした退学者は1992年度までの入学者に多かった｡ 2)入学者全体では,予定卒業者,留年者,退学者の間で高校評点,入学試験成績には差がなかったが,入学年度ごとにみると,1987,1988年度は留年者が予定卒業者に比べて入学試験の総得点が高い傾向があり,逆に1991年,1993年度は予定卒業者に比べて有意に低かった｡ 3)高校評点は,データが入手できた1991年度以降一貫して留年者の評点が予定卒業者より低く, とくに1991年,1993年度は留年者の評点が有意に低かった｡ 4)留年者も含めて,一般教育科目の成績と専門科目の成績との間に有意を正の相関がみられた｡ 5)高校評点と入学試験成績との間には軽度の相関しかみられなかったが,高校評点および入学試験総合点は入学後の一般教育科目,専門科目の成績と高い正の相関を示した｡ 6)しかし,個々の入学試験科目の得点は,入学後の成績と相関しないか,軽度の相関しかみられなかった｡ 7)国家試験不合格者は,高校評点,入学試験総合点,一般科目平均点,専門科目平均点のいずれも合格者に比べて得点が低かったが,有意差はなかった｡以上の結果から,短期大学部開設当初は留年者,退学者の中に予定卒業者より学力のある学生がいたが,年を追うごとに入学者の学力が均質化し,学力が不十分なために留年する学生が多くなってきていると言える。一般教育科目の成績と専門科目の成績が強い正の相関を示すことは,1年次の成績がそのまま2,3年次の成績に反映されることを示しており,入学当初の動機付けと勉学意欲の喚起が重要なことを示している｡高校評点や学力試験の成績は入学後の成績とよく相関しており,学生選抜の有効な指標であると考えられたが,各入試科目との相関は乏しかったことから,個々の試験科目の問題内容については改善すべき課題があると思われた｡
en-copyright=
kn-copyright=

en-aut-name=OkamotoMotoi
en-aut-sei=Okamoto
en-aut-mei=Motoi
kn-aut-name=岡本基
kn-aut-sei=岡本
kn-aut-mei=基
aut-affil-num=1
ORCID=

en-aut-name=SakiyamaJunko
en-aut-sei=Sakiyama
en-aut-mei=Junko
kn-aut-name=崎山順子
kn-aut-sei=崎山
kn-aut-mei=順子
aut-affil-num=2
ORCID=

en-aut-name=AkatsukaKazuya
en-aut-sei=Akatsuka
en-aut-mei=Kazuya
kn-aut-name=赤塚和也
kn-aut-sei=赤塚
kn-aut-mei=和也
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部保健学科検査技術科学専攻

affil-num=2
en-affil=
kn-affil=岡山大学医学部保健学科検査技術科学専攻

affil-num=3
en-affil=
kn-affil=福山臨床検査センター
en-keyword=高校評点 (school record in high school)
kn-keyword=高校評点 (school record in high school)
en-keyword=入学試験成績 (result of entrance examination)
kn-keyword=入学試験成績 (result of entrance examination)
en-keyword=入学後の学業成績 (academic record)
kn-keyword=入学後の学業成績 (academic record)
en-keyword=留年 (failure in promotion)
kn-keyword=留年 (failure in promotion)
en-keyword=退学 (withdrawal from school)
kn-keyword=退学 (withdrawal from school)
END

start-ver=1.4
cd-journal=joma
no-vol=9
cd-vols=
no-issue=2
article-no=
start-page=65
end-page=74
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990226
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Development of an aptitude scale for nursing students
kn-title=看護学生の適性に関する尺度開発の試み ―信頼性･妥当性の検証―
en-subtitle=
kn-subtitle=
en-abstract=Efforts to ensure the necessary aptitude for health care professionals as well as knowledge and skills taught to nursing students are important to provide proper health services and care. A questionnaire containing 22 items was developed to evaluate teaching effectiveness. These items were obtained from previous studies and our findings in nursing practice and teaching. Stability reliability of this method was estimated using test/retest. The correlation coefficient for individual items ranged from 0.36 to 0.71. Only 2 of the 22 items showed correlation values below 0.40. Internal reliability of the 5 subscales was determined using the Cronbach's alpha coefficient 0.83. The values ranged from 0.56 to 0.80. Five components extracted by factor analysis were identified as follows : <Leadership> <Sociability> <Spirit of inquiring> <Well-balanced personality> and <Patience>.
kn-abstract=看護教育では,看護者として必要な知識,技術のみならず看護するのにふさわしい態度や姿勢等を育成することを重視している｡このような看護者にふさわしい態度形成を援助する教育の成果を評価するために看護学生の適性に関する尺度開発を試みた｡尺度に用いる項目は,看護者にふさわしい態度や性格特性及び適性等に関する過去の文献調査と筆者等の臨床看護及び看護教育の経験とで検討し決定した｡最終的に絞り込んだ項目は,22項目であった｡この項目の信頼性･妥当性を検証するために,医療技術短大の看護学生206人を対象に質問紙調査を実施した｡信頼性については,76人を対象に再検査を実施し安定性を検討した｡その結果,相関係数の一番低い項目は｢研究心｣｢自制心｣で,0.36であった｡残りの項目は,相関係数0.40以上で,一番高い項目は｢冷静｣の0.71であった｡内的整合性を示すCronbach's α信頼性係数は,全項目では0.83であった｡因子分析の結果得られた5因子に基づく下位尺度のCronbach's α信頼性係数は,最も高いものは<リーダーシップ>0.80であり,最も低いものは<精神的成熟>0.56であった｡構成概念の妥当性を検討するために因子分析をおこなった結果,5因子が抽出された｡それぞれを<リ
ーダーシップ><社会性><探求心><精神的成熟><忍耐>と命名し,下位尺度とした｡
en-copyright=
kn-copyright=

en-aut-name=IkedaToshiko
en-aut-sei=Ikeda
en-aut-mei=Toshiko
kn-aut-name=池田敏子
kn-aut-sei=池田
kn-aut-mei=敏子
aut-affil-num=1
ORCID=

en-aut-name=KondohIsao
en-aut-sei=Kondoh
en-aut-mei=Isao
kn-aut-name=近藤勲
kn-aut-sei=近藤
kn-aut-mei=勲
aut-affil-num=2
ORCID=

en-aut-name=TanakaKoji
en-aut-sei=Tanaka
en-aut-mei=Koji
kn-aut-name=田中宏二
kn-aut-sei=田中
kn-aut-mei=宏二
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部保健学科看護学専攻

affil-num=2
en-affil=
kn-affil=岡山大学教育学部

affil-num=3
en-affil=
kn-affil=岡山大学教育学部
en-keyword=看護学生 (nursing students)
kn-keyword=看護学生 (nursing students)
en-keyword=看護教育 (nursing education)
kn-keyword=看護教育 (nursing education)
en-keyword=看護 (nursing)
kn-keyword=看護 (nursing)
en-keyword=適性 (aptitude)
kn-keyword=適性 (aptitude)
en-keyword=尺度 (scale)
kn-keyword=尺度 (scale)
END

start-ver=1.4
cd-journal=joma
no-vol=12
cd-vols=
no-issue=2
article-no=
start-page=107
end-page=117
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2002
dt-pub=20020320
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=マイクロコントローラを組み込んだ歯科インプラント動揺測定装置の開発
kn-title=Development of a microcontroller-based dental implant movement checker
en-subtitle=
kn-subtitle=
en-abstract=本研究の目的は歯科インプラントの動揺を簡易に測定できる装置の開発である｡本装置では測定プローブで一定振幅の周波数を歯科インプラントに与え､その加速度信号を検出する｡そして本研究で考察した評価基準に基づいてIM値を表示する｡さらにRigolac?やMolteno?を用い､インプラント体の長さおよび直径を変えたインプラントモデルを作製した｡400Hzにおけるモデルの機械モビリティとIM値との間には､よい相関が見られた(R(2)=0.92)｡IMチェッカーを用い､一人の測定者が行った12回の測定において､インプラントの動揺を判別することが可能であった(P<0.01)｡また4人の測定者による測定では,その平均値に対し測定者間の有意差は見られなかった(P<0.01)｡従ってIMチェッカーは十分な信頼性を有し､歯科臨床に有効であると考える｡
kn-abstract=The aim of this study was to develop a portable device (IM checker) for measuring dental implant mobility using a microcontroller. A constant amplitude and frequency vibration was applied to a dental implant model and the acceleration signal was detected using measuring probe. Then the IM score was obtained using the criteria developed
in this study. We made several implant models of different implant lengths, diameters and material of Rigolac? or Molteno?. There was a linear relationship between mechanical mobility at 400 Hz of the models and the IM scores (R(2) = 0.92). The IM checker could discriminate the mobility of dental implant models in twelve measurements with P < 0.01. There was no significant difference in the means of the IM score measured by four operators with P < 0.01. The results indicated that the IM checker had sufficient reliability and could be available in dental clinics.
en-copyright=
kn-copyright=

en-aut-name=Kusuma WijayaSastra
en-aut-sei=Kusuma Wijaya
en-aut-mei=Sastra
kn-aut-name=クスマ ウイジャヤサストラ
kn-aut-sei=クスマ ウイジャヤ
kn-aut-mei=サストラ
aut-affil-num=1
ORCID=

en-aut-name=OkaHisao
en-aut-sei=Oka
en-aut-mei=Hisao
kn-aut-name=岡久雄
kn-aut-sei=岡
kn-aut-mei=久雄
aut-affil-num=2
ORCID=

en-aut-name=SarataniKeiji
en-aut-sei=Saratani
en-aut-mei=Keiji
kn-aut-name=更谷啓治
kn-aut-sei=更谷
kn-aut-mei=啓治
aut-affil-num=3
ORCID=

en-aut-name=MatsutaniYoshio
en-aut-sei=Matsutani
en-aut-mei=Yoshio
kn-aut-name=松谷善雄
kn-aut-sei=松谷
kn-aut-mei=善雄
aut-affil-num=4
ORCID=

en-aut-name=TatsutaMitsuhiro
en-aut-sei=Tatsuta
en-aut-mei=Mitsuhiro
kn-aut-name=龍田光弘
kn-aut-sei=龍田
kn-aut-mei=光弘
aut-affil-num=5
ORCID=

en-aut-name=KawazoeTakayoshi
en-aut-sei=Kawazoe
en-aut-mei=Takayoshi
kn-aut-name=川添堯彬
kn-aut-sei=川添
kn-aut-mei=堯彬
aut-affil-num=6
ORCID=

en-aut-name=KojimaHideki
en-aut-sei=Kojima
en-aut-mei=Hideki
kn-aut-name=小嶋英幹
kn-aut-sei=小嶋
kn-aut-mei=英幹
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院自然科学研究科

affil-num=2
en-affil=
kn-affil=岡山大学医学部保健学科検査技術科学専攻

affil-num=3
en-affil=
kn-affil=大阪歯科大学有歯補綴咬合学講座

affil-num=4
en-affil=
kn-affil=大阪歯科大学有歯補綴咬合学講座

affil-num=5
en-affil=
kn-affil=大阪歯科大学有歯補綴咬合学講座

affil-num=6
en-affil=
kn-affil=大阪歯科大学有歯補綴咬合学講座

affil-num=7
en-affil=
kn-affil=隆祥産業株式会社生産本部技術部
en-keyword=Tooth mobility (歯の動揺)
kn-keyword=Tooth mobility (歯の動揺)
en-keyword=mechanical mobility (機械モビリティ)
kn-keyword=mechanical mobility (機械モビリティ)
en-keyword=dental implant (インプラント)
kn-keyword=dental implant (インプラント)
en-keyword=manual examination (触診)
kn-keyword=manual examination (触診)
END

start-ver=1.4
cd-journal=joma
no-vol=13
cd-vols=
no-issue=2
article-no=
start-page=83
end-page=90
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2003
dt-pub=20030320
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Achievement levels of students on clinical nursing practice for chronic illness
kn-title=成人看護実習(慢性期)における実習目標の到達度
en-subtitle=
kn-subtitle=
en-abstract=This paper is designed to demonstrate the relationships between each objective and the students' achievement levels for the objectives of clinical nursing practice. Seventy four students evaluated their own achievement levels related to their clinical nursing practice. Evaluation scores for each objective were analyzed. The
following results were obtained: The objective of cultivating the view of nursing and developing themselves had the highest score. Understanding the mechanism of disease, physical examination and treatment, and patient care, understanding nursing care toward patient's self care, and understanding nursing care for patient in crisis had high scores. The students, through their own nursing care, explored the meaning of each care (or each experience) and inquired about the nature of nursing. Their view of nursing and self development was formed from their own various experiences. Correlation among each objective was found. Each for clinical nursing practice has reliability and validity.
kn-abstract=実習目標の到達度及び実習目標間の関係を明らかにするために,74名の学生による実習目標の自己評価を分析した｡その結果,実習目標の到達度は,｢自己の看護観や自己成長を培う｣が最も高かった｡そして｢疾患の病態生理や検査･治療についての理解と看護援助｣｢セルフケアに向けた看護援助｣｢危機に直面している患者の看護援助｣などの看護実践面に関する目標が高値を示していた｡学生は目標に沿った看護を実践する中で,経験したひとつひとつのケアを意味づけたり,看護とは何かを探求していったと思われ,それが看護観の形成や自己成長につながっていったものと考えられた｡実習目標間の関係では,各実習目標との間に相関が見られ,それらは信頼性のある妥当な慢性期看護実習の目標であることが確認された｡
en-copyright=
kn-copyright=

en-aut-name=HayashiYuko
en-aut-sei=Hayashi
en-aut-mei=Yuko
kn-aut-name=林優子
kn-aut-sei=林
kn-aut-mei=優子
aut-affil-num=1
ORCID=

en-aut-name=KageyamaJingo
en-aut-sei=Kageyama
en-aut-mei=Jingo
kn-aut-name=景山甚郷
kn-aut-sei=景山
kn-aut-mei=甚郷
aut-affil-num=2
ORCID=

en-aut-name=NakanishiYoshiko
en-aut-sei=Nakanishi
en-aut-mei=Yoshiko
kn-aut-name=中西代志子
kn-aut-sei=中西
kn-aut-mei=代志子
aut-affil-num=3
ORCID=

en-aut-name=IshizakiHiroyuki
en-aut-sei=Ishizaki
en-aut-mei=Hiroyuki
kn-aut-name=石�ｱ博之
kn-aut-sei=石�ｱ
kn-aut-mei=博之
aut-affil-num=4
ORCID=

en-aut-name=MorimotoMichiko
en-aut-sei=Morimoto
en-aut-mei=Michiko
kn-aut-name=森本美智子
kn-aut-sei=森本
kn-aut-mei=美智子
aut-affil-num=5
ORCID=

en-aut-name=MoriKeiko
en-aut-sei=Mori
en-aut-mei=Keiko
kn-aut-name=森恵子
kn-aut-sei=森
kn-aut-mei=恵子
aut-affil-num=6
ORCID=

en-aut-name=TsuboiKeiko
en-aut-sei=Tsuboi
en-aut-mei=Keiko
kn-aut-name=坪井桂子
kn-aut-sei=坪井
kn-aut-mei=桂子
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部保健学科看護学専攻

affil-num=2
en-affil=
kn-affil=岡山大学医学部保健学科看護学専攻

affil-num=3
en-affil=
kn-affil=岡山大学医学部保健学科看護学専攻

affil-num=4
en-affil=
kn-affil=岡山大学医学部保健学科看護学専攻

affil-num=5
en-affil=
kn-affil=岡山大学医学部保健学科看護学専攻

affil-num=6
en-affil=
kn-affil=岡山大学医学部保健学科看護学専攻

affil-num=7
en-affil=
kn-affil=岡山大学医学部保健学科看護学専攻
en-keyword=慢性期看護実習 (Clinical nursing practice)
kn-keyword=慢性期看護実習 (Clinical nursing practice)
en-keyword=実習目標の到達度 (Achievement levels)
kn-keyword=実習目標の到達度 (Achievement levels)
en-keyword=自己評価 (Self-assessment)
kn-keyword=自己評価 (Self-assessment)
en-keyword=実習目標間の関係 (Relationships between each objective)
kn-keyword=実習目標間の関係 (Relationships between each objective)
END

start-ver=1.4
cd-journal=joma
no-vol=65
cd-vols=
no-issue=
article-no=
start-page=115
end-page=118
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=199409
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Relationship between vertebral transformation (or fracture) and bone mineral density in lumbar vertebrae.
kn-title=椎体変形と腰椎海綿骨骨塩量の関連-360症例の検討
en-subtitle=
kn-subtitle=
en-abstract=In 360 females, Bone mineral density (BMD) in lumbar vertebrae (L2-L4) was assessed by quantitative computed tomography (QCT), and the values obtained were compared with the frequency of vertebral transformation or fracture as assessed by lateral scan image (scanogram) by X-ray CT. A correlation was observed between the frequency of vertebral transformation (or fracture) and lumbar BMD values : BMD under 125mg/cm(3) was observed over 90% of women with vertebral transformation, and BMD under 70mg/cm(3) was found about 50% of them. These results suggest that decrease in BMD in lumbar vertebrae leads to vertebral transformation or fracture. Thus, measurement of BMD by QCT would be very useful in predicting vertebral
transformation or fractures.
kn-abstract=QCTによる腰椎海綿骨骨塩量と,圧迫骨折を含む,椎体(第11胸椎〜第4腰椎)の変形率の関係を検討した｡椎体変形率と腰椎QCT値の間の強い相関関係が確認され,椎体変形者全体の50%はQCT値70mg/cm(3)以下に分布し,90%は125mg/cm(3)以下に分布した｡さらに,この70mg/cm(3)付近での椎体変形者の割合は50%であり,125mg/cm(3)付近での椎体変形の割合は10%であった｡QCTによる腰椎海綿骨骨塩量測定値は,腰椎の変形および骨折の危険性を予
測する良好な指標であることが確認できた｡
en-copyright=
kn-copyright=

en-aut-name=NakaiMutsuo
en-aut-sei=Nakai
en-aut-mei=Mutsuo
kn-aut-name=中井睦郎
kn-aut-sei=中井
kn-aut-mei=睦郎
aut-affil-num=1
ORCID=

en-aut-name=AkiyamaTsuneo
en-aut-sei=Akiyama
en-aut-mei=Tsuneo
kn-aut-name=穐山恒雄
kn-aut-sei=穐山
kn-aut-mei=恒雄
aut-affil-num=2
ORCID=

en-aut-name=KajimotoKazuhiro
en-aut-sei=Kajimoto
en-aut-mei=Kazuhiro
kn-aut-name=梶本和宏
kn-aut-sei=梶本
kn-aut-mei=和宏
aut-affil-num=3
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=4
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=5
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院放射線室

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院放射線室

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科
en-keyword=骨粗鬆症 (osteoporosis)
kn-keyword=骨粗鬆症 (osteoporosis)
en-keyword=骨塩量 (bone mineral density)
kn-keyword=骨塩量 (bone mineral density)
en-keyword=QCT (quantitative computed tomography)
kn-keyword=QCT (quantitative computed tomography)
en-keyword=腰椎 (lumbar vertebrae)
kn-keyword=腰椎 (lumbar vertebrae)
END

start-ver=1.4
cd-journal=joma
no-vol=65
cd-vols=
no-issue=
article-no=
start-page=69
end-page=76
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=199409
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Study on the relatjonship between the bone mineral density mesured by QCT and the osteoporosis therapy.
kn-title=QCTによる経時的3回の骨塩量測定と骨粗髭症治療についての検討
en-subtitle=
kn-subtitle=
en-abstract=Bone mineral densities (BMD) were　mesured 3 times in 54 females aged 40 to 84 years old to evaluate about relationship between BMD and osteoporosis therapy or patient background factors. BMD decreased 3.1±14.6mg/cm(3) per year, and BMD values were more decreased in subjects with the age of 50's and over 70's than in those with the age of 40's and 60's. In patients with bronchial asthma or rheumatoid arthritis, treated with corticosteroids (predonisolone : 3-7.5mg/day), BMD were sigfnificantly more decreased than in patients without corticosteroid therapy. There was a significant positive correlation between BMD and body height, but no correlation between BMD and body weight, serum Ca, P, or alkaline phosphatase. No differences in background factors were found between subjects with increased BMD and those with decreased
BMD. These results indicate that female patients with corticosteroids need active treatments for the prophylaxis of osteoporosis at the age of 40's or 50's.
kn-abstract=当院通院あるいは入院中の女性患者54例を対象に骨塩量を経時的に3回測定し検討を行った。54例の骨塩量の平均は3回とも有意差はなく,年次骨塩変化量は-3.1±14.6mg/cm(3)/yearであった｡平均骨塩量の年齢別比較では40才台,50才台,60才台の順に有意な減少がみられ,60才台と70才以上との間には差は認めなかった｡また50才台及び70才以上の年代で1年当たりの骨塩量の減少が大きい傾向が窺われた｡身長と骨塩量との間に有意の正の相関を認めたが,体重との間には有意の相関を認めなかった｡血清中Ca,P及びALPと骨塩量との検討ではいずれも有意の相関を認めなかった｡骨塩変化量減少群と増加群との比較では,平均骨塩量及び背景因子の間に差を認めなかった｡女性,特にステロイド療法を必要とする患者については閉経の時期にあたる40〜50才台より積極的に骨粗髭症対策を考える必要性があると考えられた｡また運動療法については温泉プール療法自体を再検討するとともに,骨粗髭症に特異的な運動療法の確立が必要と思われた｡
en-copyright=
kn-copyright=

en-aut-name=KajimotoKazuhiro
en-aut-sei=Kajimoto
en-aut-mei=Kazuhiro
kn-aut-name=梶本和宏
kn-aut-sei=梶本
kn-aut-mei=和宏
aut-affil-num=1
ORCID=

en-aut-name=TakataIchiro
en-aut-sei=Takata
en-aut-mei=Ichiro
kn-aut-name=高田一郎
kn-aut-sei=高田
kn-aut-mei=一郎
aut-affil-num=2
ORCID=

en-aut-name=YokotaSatoshi
en-aut-sei=Yokota
en-aut-mei=Satoshi
kn-aut-name=横田聡
kn-aut-sei=横田
kn-aut-mei=聡
aut-affil-num=3
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=4
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=5
ORCID=

en-aut-name=KitaniHikaru
en-aut-sei=Kitani
en-aut-mei=Hikaru
kn-aut-name=貴谷光
kn-aut-sei=貴谷
kn-aut-mei=光
aut-affil-num=6
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=7
ORCID=

en-aut-name=KobayashiYasuaki
en-aut-sei=Kobayashi
en-aut-mei=Yasuaki
kn-aut-name=小林靖明
kn-aut-sei=小林
kn-aut-mei=靖明
aut-affil-num=8
ORCID=

en-aut-name=NakagiriYoshiyasu
en-aut-sei=Nakagiri
en-aut-mei=Yoshiyasu
kn-aut-name=中桐善康
kn-aut-sei=中桐
kn-aut-mei=善康
aut-affil-num=9
ORCID=

en-aut-name=NakaiMutsuro
en-aut-sei=Nakai
en-aut-mei=Mutsuro
kn-aut-name=中井睦郎
kn-aut-sei=中井
kn-aut-mei=睦郎
aut-affil-num=10
ORCID=

en-aut-name=AkiyamaTsuneo
en-aut-sei=Akiyama
en-aut-mei=Tsuneo
kn-aut-name=穐山恒雄
kn-aut-sei=穐山
kn-aut-mei=恒雄
aut-affil-num=11
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=7
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=8
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院産科婦人科

affil-num=9
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院産科婦人科

affil-num=10
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院放射線室

affil-num=11
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院放射線室
en-keyword=骨粗鬆症 (Osteoporosis)
kn-keyword=骨粗鬆症 (Osteoporosis)
en-keyword=骨塩量 (Bone mineral density)
kn-keyword=骨塩量 (Bone mineral density)
en-keyword=運動療法 (Exercise therapy)
kn-keyword=運動療法 (Exercise therapy)
en-keyword=QCT (quantitative computed tomograpy)
kn-keyword=QCT (quantitative computed tomograpy)
END

start-ver=1.4
cd-journal=joma
no-vol=65
cd-vols=
no-issue=
article-no=
start-page=62
end-page=68
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=199409
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=MASTシステムによる気管支喘息患者の特異的IgE抗体の検討
kn-title=Clinical evaluation of MAST system in the measurement of specific IgE antibodies in patients with bronchial asthma
en-subtitle=
kn-subtitle=
en-abstract=気管支喘息95例を対象に,MASTシステムにより吸入抗原,食餌抗原の陽性率を検討した｡その結果,吸入抗原の方が食餌抗原よりも陽性者が高率にみられ,さらに複数個の抗原に陽性の傾向が見られた｡また8名の食餌抗原陽性者の内7名が吸入抗原陽性であった｡MAST陽性率と年令,発症年令には食餌抗原では明らかな相関は見られなかったが,吸入抗原では,50才以下の症例に陽性率がやや高い傾向が,発症年令が60才以下の症例の陽性率が高い傾向が見られた｡食餌抗原では血清IgE値が300IU/ml以上の症例で陽性者がみられ,1001IU/ml以上の症例では66.7%と比較的高率であった｡一方,吸入抗原に対する陽性率は,血清IgE値が500IU/ml以上の症例で高く70%以上の陽性率であった｡以上の結果より1検体同時多項目(16項目)測定可能なMASTシステムは従来のRASTに比して臨床的に有用であると考えられた｡
kn-abstract=The serum levels of specific IgE antibodies to food allergens and inhalant allergens were evaluated in ninety five patients with bronchial asthma using the MAST system, which can measure specific IgE antibodies against sixteen different allergens with a single sample. 1. Higher positivities of specific IgE antibodies were found in
inhaled allergens than in food allergens. Specific IgE antibodies against several allergens were detected in individuals more frequently in inhaled allergens than in food allergens. 2. Positivities of specific IgE antibodies against food allergens did not correlate to patients' age and patients' age at onset. In inhaled allergens, positive
results in MAST system were frequently observed in patients under age of 50 and under age at onset of 60. 3. In subjects with high serum IgE levels, high positivities of specific IgE antibodies against inhaled allergens and food allergen were found. 4. The MAST system is suggested to be clinically more useful than RAST.
en-copyright=
kn-copyright=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=1
ORCID=

en-aut-name=KitaniHikaru
en-aut-sei=Kitani
en-aut-mei=Hikaru
kn-aut-name=貴谷光
kn-aut-sei=貴谷
kn-aut-mei=光
aut-affil-num=2
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=3
ORCID=

en-aut-name=KajimotoKazuhiro
en-aut-sei=Kajimoto
en-aut-mei=Kazuhiro
kn-aut-name=梶本和宏
kn-aut-sei=梶本
kn-aut-mei=和宏
aut-affil-num=4
ORCID=

en-aut-name=YokotaSatoshi
en-aut-sei=Yokota
en-aut-mei=Satoshi
kn-aut-name=横田聡
kn-aut-sei=横田
kn-aut-mei=聡
aut-affil-num=5
ORCID=

en-aut-name=TakadaIchiro
en-aut-sei=Takada
en-aut-mei=Ichiro
kn-aut-name=高田一郎
kn-aut-sei=高田
kn-aut-mei=一郎
aut-affil-num=6
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=7
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科
en-keyword=bronchial asthma (気管支喘息)
kn-keyword=bronchial asthma (気管支喘息)
en-keyword=specific IgE antibodies (特異的IgE抗体)
kn-keyword=specific IgE antibodies (特異的IgE抗体)
en-keyword=MAST system (MASTシステム)
kn-keyword=MAST system (MASTシステム)
END

start-ver=1.4
cd-journal=joma
no-vol=66
cd-vols=
no-issue=
article-no=
start-page=37
end-page=43
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1995
dt-pub=199509
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Study on the relationship between the bone mineral densities measured by QCT and biochemical parameters.
kn-title=QCTにより測定した骨塩量と骨代謝マーカーについての検討
en-subtitle=
kn-subtitle=
en-abstract=Bone mineral densities (BMD) were measured with QCT (quantitative computed tomography) in 24 females aged 57 to
89 years old to evaluate about relationship between BMD and biochemical parameters on bone metabolism (calcium : Ca, ionized calcium : Ca(2+), alkaline phosphatase : ALP, bone type isozyme of alkaline phosphatase : ALP 3 and osteocalcin : OC) in blood. As for exception that Ca was significantly higher in patients aged of 60's in comparison with those of 70's in the examination with regard to age, no significant differences were observed.
Significant opposite correlation (r=-0.50, p<0.01) between OC and Ca(2+) and significant positive correlation (r=0.41,
p<0.05) between OC and body bass index were observed. No significant correlation was observed between mean BMD and biochemical parameters. A trend of higher ALP 3 and lower OC was observed in adrenocortical steroid (steroid) administration group in comparison with patients with no steroid therapy. Also in steroid administration group, OC value was below 8.4ng/m? in all patients. Thus, it was suspected that the suppression of bone formation was related to the mechanism of osteoporosis induced by
steroid. Then, the further studies on the relationship
of BMD and these biochemical parameters including those of younger cases were considered necessary to clarify the mechanism of osteoporosis.
kn-abstract=当院内科に通院または入院中の女性患者24例(57〜89才,平均71.8才)を対象とし,定量的QCT法による骨塩量測定と同時に血中骨代謝マーカーを測定し検討を行った｡年齢についての検討では,カルシウム(Ca)が70才台で60才台に比べ有意に高値であった以外は年代による有意差は認められなかった｡オステオカルシン(OC)とイオン化Ca(Ca(2+))との間にr=-0.50,p<0.01の有意の逆相関を認め,OCとBody mass indexとの間に有意の正の相関(r=0.41,p<0.05)を認めた｡平均骨塩量と各生化学parameterとの間には有意な相関はみられなかった｡副腎皮質ステロイド剤(ステロイド)投与群では非投与群に比べ,投与群でALP骨型アイソザイム(ALP3)高値,OC低値の傾向がみられた｡またステロイド投与症例はすべてOC値が8.4ng/m?以下であり,ステロイドによる骨粗鬆症誘発の機序として骨形成の抑制が関与している可能性が考えられた｡今後骨塩量と骨代謝マーカーとの関連について,若年者を含めた検討が必要と考えられた｡
en-copyright=
kn-copyright=

en-aut-name=KajimotoKazuhiro
en-aut-sei=Kajimoto
en-aut-mei=Kazuhiro
kn-aut-name=梶本和宏
kn-aut-sei=梶本
kn-aut-mei=和宏
aut-affil-num=1
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=2
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=3
ORCID=

en-aut-name=YokotaSatoshi
en-aut-sei=Yokota
en-aut-mei=Satoshi
kn-aut-name=横田聡
kn-aut-sei=横田
kn-aut-mei=聡
aut-affil-num=4
ORCID=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保�ｱ泰弘
kn-aut-sei=保�ｱ
kn-aut-mei=泰弘
aut-affil-num=5
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷�ｱ勝朗
kn-aut-sei=谷�ｱ
kn-aut-mei=勝朗
aut-affil-num=6
ORCID=

en-aut-name=NakaiMutsuro
en-aut-sei=Nakai
en-aut-mei=Mutsuro
kn-aut-name=中井睦郎
kn-aut-sei=中井
kn-aut-mei=睦郎
aut-affil-num=7
ORCID=

en-aut-name=AkiyamaTsuneo
en-aut-sei=Akiyama
en-aut-mei=Tsuneo
kn-aut-name=穐山恒雄
kn-aut-sei=穐山
kn-aut-mei=恒雄
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学附属病院三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学附属病院三朝分院内科

affil-num=3
en-affil=
kn-affil=岡山大学附属病院三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学附属病院三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学附属病院三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学附属病院三朝分院内科

affil-num=7
en-affil=
kn-affil=岡山大学附属病院三朝分院放射線室

affil-num=8
en-affil=
kn-affil=岡山大学附属病院三朝分院放射線室
en-keyword=骨粗鬆症 (Osteoporosis)
kn-keyword=骨粗鬆症 (Osteoporosis)
en-keyword=骨塩量 (Bone mineral desity)
kn-keyword=骨塩量 (Bone mineral desity)
en-keyword=オステオカルシン (Osteocalcin)
kn-keyword=オステオカルシン (Osteocalcin)
en-keyword=骨型アルカリフォスファターゼ (alkaline phosphatase (bone type isozyme))
kn-keyword=骨型アルカリフォスファターゼ (alkaline phosphatase (bone type isozyme))
en-keyword=イオン化カルシウム (ionized calcium)
kn-keyword=イオン化カルシウム (ionized calcium)
END

start-ver=1.4
cd-journal=joma
no-vol=67
cd-vols=
no-issue=
article-no=
start-page=75
end-page=78
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=199611
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Gastro-biliary motility in patients with non-ulcer dyspepsia
kn-title=上腹部不定愁訴患者の胃･胆嚢運動に関する研究
en-subtitle=
kn-subtitle=
en-abstract=Subjective symptoms are quite similar between cystic duct syndrome (CDS) and non-ulcer dyspepsia (NUD) : epigastralgia, hypochondralgia and vague complaints in the
upper part of the abdomen. Recently, there has been several reports suggesting that the cause of these disorders is postprandial dysmotility in the gallbladder and stomach. However, there has been no report suggesting
incoordination of postprandial gastrobilialy motility as the cause of tha above mentioned complaints in these disorders. The aim of this study was to define the difference of postprandial gastrobiliary motility between
patients with NUD and controls. Eight patients with NUD and 10 controls were studied. Gastric emptying time of liquid meal and gallbladder contraction were measured, simultaneously. There was no significant difference between study patients and controls when gastric emptying time and gallbladder contraction rate were compared in isolation. However, when these two parameters were assessed in combination, gastric emptying time was linearly correlated with minimum ballbladder contraction time in controls but not in patients. We conclude that the incoordination between gastric emptying and minimal gallbladder contraction may be one of the major causes of the symptoms in NUD.
kn-abstract=現在,上腹部不定愁訴の原因は特定されていない｡その原因を解明するため,上腹部不定愁訴患者8人と健常対照者10人に対して液体食の胃排出能と,食事負荷による胆嚢収縮能を測定した｡胃排出時間,胆嚢収縮能はいずれも両者に有意な差は認められなかった｡健常対照者では胃排出時間と胆嚢収縮時間に有意な相関関係が認められたが,上腹部不定愁訴群では相関関係は認められなかった｡上腹部不定愁訴の原因として胃･胆嚢協調運動障害の存在が示唆
された。
en-copyright=
kn-copyright=

en-aut-name=MizushimaTakaaki
en-aut-sei=Mizushima
en-aut-mei=Takaaki
kn-aut-name=水島孝明
kn-aut-sei=水島
kn-aut-mei=孝明
aut-affil-num=1
ORCID=

en-aut-name=YamamotoRyoichi
en-aut-sei=Yamamoto
en-aut-mei=Ryoichi
kn-aut-name=山本良一
kn-aut-sei=山本
kn-aut-mei=良一
aut-affil-num=2
ORCID=

en-aut-name=MatsumuraNaoki
en-aut-sei=Matsumura
en-aut-mei=Naoki
kn-aut-name=松村直樹
kn-aut-sei=松村
kn-aut-mei=直樹
aut-affil-num=3
ORCID=

en-aut-name=ChowdhuryRiaz
en-aut-sei=Chowdhury
en-aut-mei=Riaz
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=KatoTadahiro
en-aut-sei=Kato
en-aut-mei=Tadahiro
kn-aut-name=加藤匡宏
kn-aut-sei=加藤
kn-aut-mei=匡宏
aut-affil-num=5
ORCID=

en-aut-name=OchiKoji
en-aut-sei=Ochi
en-aut-mei=Koji
kn-aut-name=越智浩二
kn-aut-sei=越智
kn-aut-mei=浩二
aut-affil-num=6
ORCID=

en-aut-name=TanakaJuntaro
en-aut-sei=Tanaka
en-aut-mei=Juntaro
kn-aut-name=田中淳太郎
kn-aut-sei=田中
kn-aut-mei=淳太郎
aut-affil-num=7
ORCID=

en-aut-name=HaradaHideo
en-aut-sei=Harada
en-aut-mei=Hideo
kn-aut-name=原田英雄
kn-aut-sei=原田
kn-aut-mei=英雄
aut-affil-num=8
ORCID=

en-aut-name=YokotaSatoshi
en-aut-sei=Yokota
en-aut-mei=Satoshi
kn-aut-name=横田聡
kn-aut-sei=横田
kn-aut-mei=聡
aut-affil-num=9
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=10
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=11
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=12
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第二内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部第二内科

affil-num=3
en-affil=
kn-affil=岡山大学医学部臨床検査医学

affil-num=4
en-affil=
kn-affil=岡山大学医学部臨床検査医学

affil-num=5
en-affil=
kn-affil=岡山大学医学部臨床検査医学

affil-num=6
en-affil=
kn-affil=岡山大学医学部臨床検査医学

affil-num=7
en-affil=
kn-affil=岡山大学医学部臨床検査医学

affil-num=8
en-affil=
kn-affil=岡山大学医学部臨床検査医学

affil-num=9
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=10
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=11
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=12
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科
en-keyword=胃運動 (Gastric motility)
kn-keyword=胃運動 (Gastric motility)
en-keyword=胆嚢運動 (Biliary motility)
kn-keyword=胆嚢運動 (Biliary motility)
en-keyword=不定愁訴 (indefinite complaint)
kn-keyword=不定愁訴 (indefinite complaint)
END

start-ver=1.4
cd-journal=joma
no-vol=67
cd-vols=
no-issue=
article-no=
start-page=28
end-page=34
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=199611
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Ia型(単純気管支れん縮型)喘息における気道過敏性について…年齢および気管支肺胞洗浄液中の細胞成分との関連について
kn-title=Bronchial hyperresponsiveness in type Ia (simple bronchoconstriction) asthma Relationship to patient age and the proportions of bronchoalveolar cells
en-subtitle=
kn-subtitle=
en-abstract=気管支喘息患者Ia型(単純気管支れん縮型)39人(Ia-1型25人,Ia-2型14人)の気道過敏性を年齢,呼吸機能検査,気管支肺胞洗浄液(BAL)中の細胞成分と関連で検討を行った｡1.BAL液中の好酸球の比率はIa-1型に比べIa-2型で優位に高値であった｡2.メサコリンに対しての過敏性はIa-1型とIa-2型とで差を認めなかった｡3.気道過敏性はどちらの病型においても年齢にともなって減弱する傾向にあったが,一秒率及びBAL液中の好中球,リンパ球の比率とは相関しなかった｡4.メサコリンに対しての気道過敏性はIa-1型,Ia-2型ともにBAL液中の好酸球の比率が増加するにしたがって亢進した｡以上より単純気管支れん縮型(Ia型)の気管支喘息患者の気道過敏性はその年齢,BAL液中の好酸球の比率に相関することが示唆された｡
kn-abstract=Bronchial hyperresponsiveness was examined in relation to age, ventilatory function, and the proportion of bronchoalveolar lavage (BAL) cells in 39 patients with type Ia asthma (simple bronchoconstriction) (25 with type Ia-1 and 14 with type Ia-2), classified by clinical symptoms. 1. The proportion of BAL eosinophils was significantly higher in type Ia-2 than that in type Ia-1 asthma patients. 2. Bronchial reactivity to methacholine was not different between type Ia-1 and type Ia-2 asthma patients. 3. Bronchial hyperreactivity tended to decrease as patient age was higher in both types of asthma. Neither ventilatory function (FEV1.0%) nor the proportions of BAL lymphocytes and neutrophils was not correlated with bronchial hyperresponsiveness in both types of asthma. 4. Bronchial reactivity to methacholine more dereased with the increase in the proportion of BAL eosinophils in both type Ia-1 and Ia-2 asthma patients. The results show that bronchial hyperresponsiveness in patients with type Ia asthma is correlated to patients age and the proportion of BAL eosinophils.
en-copyright=
kn-copyright=

en-aut-name=AshidaKozo
en-aut-sei=Ashida
en-aut-mei=Kozo
kn-aut-name=芦田耕三
kn-aut-sei=芦田
kn-aut-mei=耕三
aut-affil-num=1
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=2
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=3
ORCID=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保崎泰弘
kn-aut-sei=保崎
kn-aut-mei=泰弘
aut-affil-num=4
ORCID=

en-aut-name=YokotaSatoshi
en-aut-sei=Yokota
en-aut-mei=Satoshi
kn-aut-name=横田聡
kn-aut-sei=横田
kn-aut-mei=聡
aut-affil-num=5
ORCID=

en-aut-name=TsugenoHirofumi
en-aut-sei=Tsugeno
en-aut-mei=Hirofumi
kn-aut-name=柘野浩史
kn-aut-sei=柘野
kn-aut-mei=浩史
aut-affil-num=6
ORCID=

en-aut-name=TakeuchiKazuaki
en-aut-sei=Takeuchi
en-aut-mei=Kazuaki
kn-aut-name=竹内一昭
kn-aut-sei=竹内
kn-aut-mei=一昭
aut-affil-num=7
ORCID=

en-aut-name=NawaYuichiro
en-aut-sei=Nawa
en-aut-mei=Yuichiro
kn-aut-name=名和由一郎
kn-aut-sei=名和
kn-aut-mei=由一郎
aut-affil-num=8
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=9
ORCID=

en-aut-name=OchiKoji
en-aut-sei=Ochi
en-aut-mei=Koji
kn-aut-name=越智浩二
kn-aut-sei=越智
kn-aut-mei=浩二
aut-affil-num=10
ORCID=

en-aut-name=HaradaHideo
en-aut-sei=Harada
en-aut-mei=Hideo
kn-aut-name=原田英雄
kn-aut-sei=原田
kn-aut-mei=英雄
aut-affil-num=11
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=7
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=8
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=9
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=10
en-affil=
kn-affil=岡山大学医学部臨床検査医学

affil-num=11
en-affil=
kn-affil=岡山大学医学部臨床検査医学
en-keyword=Bronchial hyperresponsiveness
kn-keyword=Bronchial hyperresponsiveness
en-keyword=Type Ia asthma
kn-keyword=Type Ia asthma
en-keyword=Patient age
kn-keyword=Patient age
en-keyword=BAL eosinophiIs
kn-keyword=BAL eosinophiIs
END

start-ver=1.4
cd-journal=joma
no-vol=70
cd-vols=
no-issue=
article-no=
start-page=53
end-page=60
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=199912
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=気管支喘息症例における皮質骨海綿化
kn-title=Cortical bone porosity in patients with asthma
en-subtitle=
kn-subtitle=
en-abstract=【目的】これまでに我々は,気管支喘息症例において経口ステロイドによる皮質骨骨密度,容積の減少が骨折に関与する新知見を報告し,閉経後女性では皮質骨骨密度一容積の減少はステロイド投与量にかかわらず一定であることを報告してきた｡この皮質骨骨密度-容積の関係において性差による違いを検討するために,男性,女性患者の両方について検討を行った｡【方法】対象はステロイド依存性喘息99例(男性26例,女性73例)｡性別,年齢,経口ステロイド積算総投与量により6群に分類した｡椎体圧迫骨折は�]線側面像にて評価
し,皮質骨容積比および皮質骨骨密度はpQCT(Stratec XCT960)を用いて測定した｡それぞれの群の皮質骨骨密度-容積比の関係を算出し比較検定をおこなった｡【結果】それぞれの群の皮質骨の骨密度と容積比は有意に相関した｡それぞれの群の皮質骨骨密度-容積比の傾きは,いずれも有意差を認めなかった｡【結論】気管支喘息症例におけるステロイド投与による皮質骨の骨密度と容積の減少は,性別にかかわらずほぼ一定で,皮質骨は内側と外側において同様に海綿化してゆくと考えられた｡
kn-abstract=In previous studies, we have demonstrated that chronic administration of systemic glucocorticoids decreases cortical bone mineral density (BMD), cortical bone volume, bone strength, and induces development of pathologic fractures in asthmatic patients. We have also demonstrated that glucocorticoid administration appears to be responsible for the process of cortical bone porosity at both endosteal and intracortical sites in postmenopausal asthmatic patients. There is a difference of gonadal hormones between male and female. To investigate the influence of hormonal difference on glucocorticoid-induced cortical bone porosity, we studied cortical bone volume and
BMD in both male and female patients with asthma in this report. A total of 99 asthmatic patients (male 26 cases, female 73 cases) were enrolled in the study. Peripheral quantitative computed tomography (pQCT) was used to measure
cortical BMD and relative cortical volume. The cortical volume-density relationship appeared to remain constant regardless of the level of systemic glucocorticoid administration, age or sex, suggesting cortical bone
porosity causes similar and simultaneous decreases in cortical bone volume and density. In conclusion, glucocorticoid administration appears to be responsible for the process of cortical bone porosity at both endosteal and intracortical sites despite the gonadal
hormonal differences.
en-copyright=
kn-copyright=

en-aut-name=TsugenoHirofumi
en-aut-sei=Tsugeno
en-aut-mei=Hirofumi
kn-aut-name=柘野浩史
kn-aut-sei=柘野
kn-aut-mei=浩史
aut-affil-num=1
ORCID=

en-aut-name=NakaiMutsuro
en-aut-sei=Nakai
en-aut-mei=Mutsuro
kn-aut-name=中井睦郎
kn-aut-sei=中井
kn-aut-mei=睦郎
aut-affil-num=2
ORCID=

en-aut-name=OkamotoMakoto
en-aut-sei=Okamoto
en-aut-mei=Makoto
kn-aut-name=岡本誠
kn-aut-sei=岡本
kn-aut-mei=誠
aut-affil-num=3
ORCID=

en-aut-name=HaradaSeishi
en-aut-sei=Harada
en-aut-mei=Seishi
kn-aut-name=原田誠之
kn-aut-sei=原田
kn-aut-mei=誠之
aut-affil-num=4
ORCID=

en-aut-name=TakataShingo
en-aut-sei=Takata
en-aut-mei=Shingo
kn-aut-name=高田真吾
kn-aut-sei=高田
kn-aut-mei=真吾
aut-affil-num=5
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=6
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=7
ORCID=

en-aut-name=AshidaKozo
en-aut-sei=Ashida
en-aut-mei=Kozo
kn-aut-name=芦田耕三
kn-aut-sei=芦田
kn-aut-mei=耕三
aut-affil-num=8
ORCID=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保崎泰弘
kn-aut-sei=保崎
kn-aut-mei=泰弘
aut-affil-num=9
ORCID=

en-aut-name=AkiyamaTsuneo
en-aut-sei=Akiyama
en-aut-mei=Tsuneo
kn-aut-name=穐山恒雄
kn-aut-sei=穐山
kn-aut-mei=恒雄
aut-affil-num=10
ORCID=

en-aut-name=TsujiTakao
en-aut-sei=Tsuji
en-aut-mei=Takao
kn-aut-name=辻孝夫
kn-aut-sei=辻
kn-aut-mei=孝夫
aut-affil-num=11
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=12
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院放射線室

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=7
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=8
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=9
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=10
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院放射線室

affil-num=11
en-affil=
kn-affil=岡山大学医学部第一内科

affil-num=12
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科
en-keyword=bronchial asthma
kn-keyword=bronchial asthma
en-keyword=systemic glucocorticoid
kn-keyword=systemic glucocorticoid
en-keyword=cortical bone
kn-keyword=cortical bone
en-keyword=cortical porosity
kn-keyword=cortical porosity
en-keyword=peripheral quantitative computed tomography
kn-keyword=peripheral quantitative computed tomography
END

start-ver=1.4
cd-journal=joma
no-vol=70
cd-vols=
no-issue=
article-no=
start-page=36
end-page=42
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=199912
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=サーモグラフィーによる体表面温度の測定 3.体表面温度の回復率と末消血流量との相関
kn-title=Evaluation of Body Surface Temperature by Thermography 3. Correlation between the peripheral circulation estimatedby Laser-Doppler blood flowmetry and thermography.
en-subtitle=
kn-subtitle=
en-abstract=末梢神経障害を有する糖尿病患者の末梢循環障害の程度を数量的に検討する目的で､下肢に冷感ならびにしびれ感または疼痛を訴える糖尿病患者9症例と健常ボランティア3例の計12例(平均年齢59歳)についてサーモグラフィーを用いて体表面温度を測定した｡更に,サーモグラフィーで得られた結果と末梢皮膚血流量をレーザードプラー血流計を用いて測定して得られた結果と比較した｡サーモグラフィーによる測定で得られた結果は回復率として数量化して表示された｡回復率の算出方法は回復率= [冷水負荷後の特定温度27℃以
上の体表面温度のサーモグラフィーのPixelの総数]÷ [冷水負荷前の特定温度27℃以上の体表面温度のサーモグラフィーのPixelの総数]×100%で求めた｡レーザードプラ-血流計を用いて測定して得られた末梢血流量は左右それぞれ5カ所,計10カ所の測定値の平均で表示した｡その結果,末梢皮膚温度の回復率と末梢皮膚の血流量との問には正の相関関係(r=0.68,p<0.01)が認められた｡次に,末梢皮膚血流量について,室温20℃安静15分後,温水36℃浸水負荷10分後,冷水20℃浸水負荷30分後の異なる3条件について､またサーモグラフィーで得られた結果を,画像処理の過程で用いられた,26℃,27℃,28℃の3つの異なる特定温度との関連について検討を行なった｡対象は,下肢に冷感ならびにしびれ感または疼痛を訴える糖尿病患者16症例(平均年齢69歳,平均HbAIC9.6%)について測定した｡その結果,末梢皮膚
血流量は冷水20℃浸水負荷30分後に測定して得られた結果と,回復率は特定温度27℃で画像処理して得られた結果とが最も相関が高い(r=0.59,p=0.0002)ことが示された｡`次に,相関が高い条件は,室温20℃安静15分後に血流量を測定した場合(r=0.483,p=0.0002)であった｡そして温
水36℃浸水負荷10分後に測定して得られた結果とが最も相関関係が低い結果となった｡更に,冷水20℃浸水負荷30分後に測定して得られた結果を温水36℃浸水負荷10分後に測定して得られた結果で割った比を%で表示したところ回復率とこの比との間には正の相関関係(r=0.46,p<0.0001)が認められた｡このことから,温水36℃負荷時と,冷水20℃負荷時との差が大きい患者
において末梢皮膚温度の低下が著しいことが示された｡これまで悲観血的に測定されてきたサーモグラフィーによる末梢循環の数量的評価の試みは,レーザー血流計による結果と組み合わせることで,両者の間に正の相関関係が示されたことにより,今後,数量化された客観的評価を可能にした｡
kn-abstract=The body surface peripheral circulation in 12 cases,　including 9 patients with　diabetes mellitus who were suffering coldness, numbness or pain in their feet, and 3
healthy volunteers was examined using Laser-Doppler blood flowmetry. At the same time, the body surface temperature was estimated by thermography. Thermographic results were analyzed quantitatively by calculating a recovery ratio as : Recovery ratio = [Total counts of thermography(Pixels) over temperature (T) after cold loading] ÷ [Initial counts over T before cold loading] x 100(%). The recovery ratio and the blood flow were correlated, r=0.68, p<O.01. The peripheral circulation of 16 patients with diabetes mellitus was observed at three different conditions including, l)placed at room temperature at 20℃for 15 min, 2) submerged and warmed for 5 min in a hot bath at 36℃(i.e. hot loading), and 3) submerged and cooled for 5 min in a water bath at 20℃ (i.e. cold loading). Three different baseline temperatures, 26℃, 27℃ and 28 ℃, were used in processing the　thermographic results into pictures. The highest correlation (r=0.59, p=0.0002) was
obtained under the condition of cold loading using a baseline temperature limitation of27℃.The difference ratio (%) of blood flow was calculated as the blood flow at cold
loading divided by the blood flow at hot loading in these 16 patients. The difference　ratio of the blood flow and the recovery ratio of thermography were correlated,
r=0.46, p<O.OOO1. We found a strong correlation between the results of Laser-Doppler blood flowmetry and one of thermographic methods used to monitor peripheral circulation in patients with diabetes mellitus. Cold loading using a baseline temperature limitation of 27℃
were recommended for further examinations. Patients with low blood flow as well as　with large differences in their peripheral circulation between cold loading and hot　loading had severe coldness in their body surface temperature. We showed the usefulness of the results of thermography, when quantified by picture processing using computer software, in relation with the results of Laser-Doppler blood flowmetry.
en-copyright=
kn-copyright=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保崎泰弘
kn-aut-sei=保崎
kn-aut-mei=泰弘
aut-affil-num=1
ORCID=

en-aut-name=TakataShingo
en-aut-sei=Takata
en-aut-mei=Shingo
kn-aut-name=高田真吾
kn-aut-sei=高田
kn-aut-mei=真吾
aut-affil-num=2
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=3
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=4
ORCID=

en-aut-name=AshidaKozo
en-aut-sei=Ashida
en-aut-mei=Kozo
kn-aut-name=芦田耕三
kn-aut-sei=芦田
kn-aut-mei=耕三
aut-affil-num=5
ORCID=

en-aut-name=TsugenoHirofumi
en-aut-sei=Tsugeno
en-aut-mei=Hirofumi
kn-aut-name=柘野浩史
kn-aut-sei=柘野
kn-aut-mei=浩史
aut-affil-num=6
ORCID=

en-aut-name=OkamotoMakoto
en-aut-sei=Okamoto
en-aut-mei=Makoto
kn-aut-name=岡本誠
kn-aut-sei=岡本
kn-aut-mei=誠
aut-affil-num=7
ORCID=

en-aut-name=HaradaSeishi
en-aut-sei=Harada
en-aut-mei=Seishi
kn-aut-name=原田誠之
kn-aut-sei=原田
kn-aut-mei=誠之
aut-affil-num=8
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=9
ORCID=

en-aut-name=OchiKoji
en-aut-sei=Ochi
en-aut-mei=Koji
kn-aut-name=越智浩二
kn-aut-sei=越智
kn-aut-mei=浩二
aut-affil-num=10
ORCID=

en-aut-name=TsujiTakao
en-aut-sei=Tsuji
en-aut-mei=Takao
kn-aut-name=辻孝夫
kn-aut-sei=辻
kn-aut-mei=孝夫
aut-affil-num=11
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=7
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=8
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=9
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=10
en-affil=
kn-affil=岡山大学医学部臨床検査医学

affil-num=11
en-affil=
kn-affil=岡山大学医学部第一内科
en-keyword=サーモグラフィー (thermography)
kn-keyword=サーモグラフィー (thermography)
en-keyword=レーザードプラー血流計 (Laser-Doppler blood flowmetry)
kn-keyword=レーザードプラー血流計 (Laser-Doppler blood flowmetry)
en-keyword=糖尿病 (diabetes mellitus)
kn-keyword=糖尿病 (diabetes mellitus)
en-keyword=末梢循環 (peripheral circulation)
kn-keyword=末梢循環 (peripheral circulation)
en-keyword=冷水負荷 (cold loading)
kn-keyword=冷水負荷 (cold loading)
END

start-ver=1.4
cd-journal=joma
no-vol=70
cd-vols=
no-issue=
article-no=
start-page=28
end-page=35
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=199912
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=気管支喘息症例における気道過敏性と鼻腔･副鼻腔疾患の関係に関する検討
kn-title=Relationship between bronchial hyperresponsivenessand nasosinus lesions in patients with bronchial asthma
en-subtitle=
kn-subtitle=
en-abstract=鼻腔･副鼻腔疾患はしばしば気管支喘息症例に合併が認められ,喘息症例の下気道病態に影響を及ぼしている可能性が考えられる｡今回,気管支喘息17例において,CTを用いて上顎洞の不透明化率･鼻腔粘膜肥厚を計測し,アトピー性の有無,喘息の重症度,気道過敏性との関係を検討した｡上顎洞不透明化率は全上顎洞面積の総計に対する不透明化領域面積総計として計算を行った｡上顎洞不透明化率はアトピー性の有無で差は認められなかったが,鼻腔粘膜はアトピー性喘息症例で有意に肥厚していた｡重症気管支喘息における上顎
洞不透明化率は,中等症および軽症喘息症例に比べ有意に高値であった｡鼻腔粘膜肥厚は中等症喘息症例に比べ,軽症症例で有意に肥厚していた｡気道過敏性(Dmin)は上顎洞不透明化率とのあいだに弱い負の相関が認められた(rs=-0.551,p=0.0276).鼻粘膜肥厚と気道過敏性は相関が認められなかった｡今回の結果から副鼻腔病変が気道過敏性･喘息重症度に影響を及ぼしている可能性が考えられ.副鼻腔疾患の治療により喘息症状の改善に繋がる可能性が考えられた。
kn-abstract=Pathological changes of nasosinus occur often in subjects with bronchial asthma. Coexisting nasosinus lesion may affect pathophysiology of lower respiratory tract in asthmatics. The extent of nasal and sinus lesion was quantified in 17 patients with bronchial asthma, and their relationships to atopic status, asthma severity and bronchial hyperresponsiveness were evaluated in this study. Opacification degree of maxillary sinuses and nasal mucosa thickening were quantified using CT scans. The
opacification degree was evaluated as (total opacification area)/(total maxillary sinus area). Although the opacification degree of maxillary sinuses in atopic patients showed no significant difference compared with that in non-atopic patients, maximum nasal mucosa thickening in atopic patients had a significant difference compared with that in non-atopic patients (p=0.028). In severe asthmatics, the opacification degree of maxillary sinuses was significantly more prominent compared with those in moderate and mild asthmatics (p=0.0005, p=0.036, respectively). Significantly marked nasal mucosa thickening was recognized in mild asthmatics compared with that in moderate asthmatics (p=0.0462). Regarding bronchial hyperresponsiveness, a significant correlation
between Dmin and the opacification degree of maxillary sinuses was observed (rs= -0.551, p=0.0276). Nasal mucosa thickening had no correlation with bronchial hyperresponsiveness. The results suggest that sinusitis may affect bronchial hyperresponsiveness and asthma severity. Treatment of sinusitis may lead to improvement
of asthma symptoms.
en-copyright=
kn-copyright=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=1
ORCID=

en-aut-name=TakataShingo
en-aut-sei=Takata
en-aut-mei=Shingo
kn-aut-name=高田真吾
kn-aut-sei=高田
kn-aut-mei=真吾
aut-affil-num=2
ORCID=

en-aut-name=OkamotoMakoto
en-aut-sei=Okamoto
en-aut-mei=Makoto
kn-aut-name=岡本誠
kn-aut-sei=岡本
kn-aut-mei=誠
aut-affil-num=3
ORCID=

en-aut-name=TsugenoHirofumi
en-aut-sei=Tsugeno
en-aut-mei=Hirofumi
kn-aut-name=柘野浩史
kn-aut-sei=柘野
kn-aut-mei=浩史
aut-affil-num=4
ORCID=

en-aut-name=AshidaKozo
en-aut-sei=Ashida
en-aut-mei=Kozo
kn-aut-name=芦田耕三
kn-aut-sei=芦田
kn-aut-mei=耕三
aut-affil-num=5
ORCID=

en-aut-name=HaradaSeishi
en-aut-sei=Harada
en-aut-mei=Seishi
kn-aut-name=原田誠之
kn-aut-sei=原田
kn-aut-mei=誠之
aut-affil-num=6
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=7
ORCID=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保崎泰弘
kn-aut-sei=保崎
kn-aut-mei=泰弘
aut-affil-num=8
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=9
ORCID=

en-aut-name=HaradaMine
en-aut-sei=Harada
en-aut-mei=Mine
kn-aut-name=原田実根
kn-aut-sei=原田
kn-aut-mei=実根
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=7
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=8
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=9
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=10
en-affil=
kn-affil=岡山大学医学部第二内科
en-keyword=気管支喘息 (bronchial asthma)
kn-keyword=気管支喘息 (bronchial asthma)
en-keyword=副鼻腔炎 (sinusitis)
kn-keyword=副鼻腔炎 (sinusitis)
en-keyword=CT所見 (CT findings)
kn-keyword=CT所見 (CT findings)
en-keyword=気道過敏性 (hyperresponsiveness)
kn-keyword=気道過敏性 (hyperresponsiveness)
END

start-ver=1.4
cd-journal=joma
no-vol=70
cd-vols=
no-issue=
article-no=
start-page=17
end-page=27
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=199912
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=気管支喘息における胸部HRCT所見の臨床[光延文裕1]的意義
kn-title=Evaluation of low attenliation area (LAA) of the lungs in patients with reversible airway obstruction by high resolution computed tomography (HRCT).
en-subtitle=
kn-subtitle=
en-abstract=【目的】気管支喘息症例において胸部HRCTを用いて% LAA(Lowattenuationarea)を評価し,臨床病態との関連を検討する｡
【対象と方法】気管支喘息症例81例ならびに健常者22例を対象とした｡大動脈弓部,下葉分岐部,横隔膜上3cmの3スライスを撮影し,胸部CT値の演算によりCT値が-950HU以下の% LAA,さらに3スライス中の最大% LAAと3スライスの平均CT値を算出した｡その値と年齢,発症年齢,罹病期間,性別,喫煙歴,重症度,病型,肺機能との関連を検討した｡【結果】1.最大% LAAは平均CT値と強い相関を示した(r=-0.916,p<0.0001)。2.最大% LAAは喫煙喘息患者において非喫煙喘息患者,喫煙ならびに非喫煙健常者に比較して喫煙者において有意に高値を示した｡% LAAは喫煙者,非喫煙者ともに重症例において有意に高値を示した｡3.最大% LAAは肺機能では1秒率(r=-0.611,p<0.0001),全肺気量(r=-0.391,p<0.0001)と有意な相関を示した｡4.最大% LAAは喘息の重症度とは有意の竿間を示したが,病型とは関連は見られなかった｡
【考案】喘息患者におけるHRCTによる最大% LAAは喫煙,重症度,肺機能と関連を示しており,気管支喘息の臨床病態を反映する可能性が示唆された｡
kn-abstract=The significance of the low attenuation area (LAA) of the lungs on high resolution computed tomography (HRCT) has not been determined in patients with asthma. We examined the relationship between the percentage of lung area with CT numbers lower than -950HU (% LAA) and the mean CT number in 81 patients with reversible airway obstruction (asthma) and in 22 healthy subjects, as well as the relationship between maximal % LAA and various parameters of pulmonary function, smoking history, disease severity and allergic type in the asthmatic subjects. The mean CT
number was obtained by scans at three anatomic levels, and maximal % LAA was the % LAA which had the largest value of those measured at the three anatomic levels of the lung.
We found that: 1. The mean CT number was closely related to the maximal % LAA of the lungs in all subjects studied (r= -0.916, p<O.OOO1). 2. The maximal % LAA in asthmatics with a previous smoking history (median: 20.1) was significantly larger than that in asthmatics without a smoking history (median: 10.8), and that in healthy
subjects with (median: 8.8) and without a history of smoking (median: 10.4). 3. The maximal % LAA was significantly correlated with FEV1/FVC (r=-0.611, p<O.OOO1)
and TLC (r=0.391, p=0.0068) in the asthmatic subjects. 4. The maximal % LAA was significantly correlated with the severity of asthma (p<O.01), but not with the etiology of asthma. This study suggests that the maximal % LAA is influenced by disease severity in patients with asthma, and that a smoking history has a more significant effect on the pulmonary function of asthmatics than healthy individuals.
en-copyright=
kn-copyright=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=1
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=2
ORCID=

en-aut-name=AshidaKozo
en-aut-sei=Ashida
en-aut-mei=Kozo
kn-aut-name=芦田耕三
kn-aut-sei=芦田
kn-aut-mei=耕三
aut-affil-num=3
ORCID=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保崎泰弘
kn-aut-sei=保崎
kn-aut-mei=泰弘
aut-affil-num=4
ORCID=

en-aut-name=TsugenoHirofumi
en-aut-sei=Tsugeno
en-aut-mei=Hirofumi
kn-aut-name=柘野浩史
kn-aut-sei=柘野
kn-aut-mei=浩史
aut-affil-num=5
ORCID=

en-aut-name=OkamotoMakoto
en-aut-sei=Okamoto
en-aut-mei=Makoto
kn-aut-name=岡本誠
kn-aut-sei=岡本
kn-aut-mei=誠
aut-affil-num=6
ORCID=

en-aut-name=HaradaSeishi
en-aut-sei=Harada
en-aut-mei=Seishi
kn-aut-name=原田誠之
kn-aut-sei=原田
kn-aut-mei=誠之
aut-affil-num=7
ORCID=

en-aut-name=NakaiMutsuo
en-aut-sei=Nakai
en-aut-mei=Mutsuo
kn-aut-name=中井陸郎
kn-aut-sei=中井
kn-aut-mei=陸郎
aut-affil-num=8
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=9
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=3
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=7
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=8
en-affil=
kn-affil=岡山大学三朝分院放射線科

affil-num=9
en-affil=
kn-affil=岡山大学三朝分院内科
en-keyword=low attenuation area
kn-keyword=low attenuation area
en-keyword=high resolution computed tomography
kn-keyword=high resolution computed tomography
en-keyword=reversible airway obstruction
kn-keyword=reversible airway obstruction
END

start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=
article-no=
start-page=59
end-page=67
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2001
dt-pub=20010201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=ステロイド依存性気管支喘息症例の病的骨折と皮質骨傷害の検討
kn-title=Glucocorticoid-induced cortical bone porosity in postmenopausal patients with asthma
en-subtitle=
kn-subtitle=
en-abstract=【目的】骨強度には皮質骨の状態が主に関与するため，全身ステロイド療法に伴う病的骨折と皮質骨障害について検討した。【方法】閉経後女性気管支喘息患者82例で，ステロイド依存性群と非依
存群において，椎体骨折数，槙骨皮質骨骨密度，皮質骨容量，骨強度（SSI）を�]線側面像とpQCTを用いて検討した。
【結果】ステロイド依存群はステロイド非依存群に比べて，椎体圧迫骨折数は有意に多く，榛骨皮質骨骨密度，皮質骨容積比，骨強度は各々有意に低下していた。また，皮質骨骨密度と容積は一定の割合で減少していた。椎体圧迫骨折数は皮質骨骨密度，皮質骨容積比，骨強度の全てと高い相関を認めた。
【結論】ステロイド依存性気管支暗息症例においては，皮質骨の骨
密度と容量が同時に減少して骨強度が減少することによって，病的骨折が発症すると考えられた。
kn-abstract=In a previous study, we demonstrated that chronic administration of systemic glucocorticoids decreases cortical bone mineral density (BMD) and induces development of pathologic fractures in asthmatic patients. To investigate cortical bone porosity due to glucocorticoids, we studied cortical bone volume, BMD, bone strength, and fractures in patients with asthma in this report.
A total of 82 postmenopausal asthmatic patients were enrolled in the study. Vertebral fractures were diagnosed via plain spinal radiograms. Peripheral quantitative computed tomography (pQCT) was used to measure cortical BMD, relative cortical volume, and Strength Strain Index (SSI). Multiple regression analysis, Student's t test, and other statistical analyses were performed.
Patients with systemic glucocorticoids therapy had lower cortical BMD, relative cortical volume, SSI, and more number of vertebral fractures than patients without it.
Lifetime cumulative dose of glucocorticoids was related to cortical BMD, relative cortical volume, SSI, and the number of vertebral fractures. The cortical volumedensity
relationship appeared to remain constant regardless of systemic glucocorticoid administration. The number of vertebral fractures correlated highly with cortical
BMD, relative cortical volume, and SSI at the radius.
In conclusion, systemic glucocorticoid administration decreases cortical bone density, cortical bone volume, and bone strength. G lucocorticoid administration appears to be
responsible for the process of cortical bone porosity at both endosteal and intracortical sites. Given that both cortical bone density and volume provide bone strength, cortical
bone porosity was seen to contribute to glucocorticoid - induced bone strength loss and fractures.
en-copyright=
kn-copyright=

en-aut-name=TsugenoHirofumi
en-aut-sei=Tsugeno
en-aut-mei=Hirofumi
kn-aut-name=柘野浩史
kn-aut-sei=柘野
kn-aut-mei=浩史
aut-affil-num=1
ORCID=

en-aut-name=GotoBunrei
en-aut-sei=Goto
en-aut-mei=Bunrei
kn-aut-name=後藤文禮
kn-aut-sei=後藤
kn-aut-mei=文禮
aut-affil-num=2
ORCID=

en-aut-name=NakaiMutsuro
en-aut-sei=Nakai
en-aut-mei=Mutsuro
kn-aut-name=中井睦郎
kn-aut-sei=中井
kn-aut-mei=睦郎
aut-affil-num=3
ORCID=

en-aut-name=OkamotoMakoto
en-aut-sei=Okamoto
en-aut-mei=Makoto
kn-aut-name=岡本誠
kn-aut-sei=岡本
kn-aut-mei=誠
aut-affil-num=4
ORCID=

en-aut-name=TakataSingo
en-aut-sei=Takata
en-aut-mei=Singo
kn-aut-name=高田真吾
kn-aut-sei=高田
kn-aut-mei=真吾
aut-affil-num=5
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=6
ORCID=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保�ｱ泰弘
kn-aut-sei=保�ｱ
kn-aut-mei=泰弘
aut-affil-num=7
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=8
ORCID=

en-aut-name=AshidaKozo
en-aut-sei=Ashida
en-aut-mei=Kozo
kn-aut-name=芦田耕三
kn-aut-sei=芦田
kn-aut-mei=耕三
aut-affil-num=9
ORCID=

en-aut-name=AkiyamaTsuneo
en-aut-sei=Akiyama
en-aut-mei=Tsuneo
kn-aut-name=穐山恒雄
kn-aut-sei=穐山
kn-aut-mei=恒雄
aut-affil-num=10
ORCID=

en-aut-name=TsujiTakao
en-aut-sei=Tsuji
en-aut-mei=Takao
kn-aut-name=辻孝夫
kn-aut-sei=辻
kn-aut-mei=孝夫
aut-affil-num=11
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=12
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=2
en-affil=
kn-affil=カルシウム研究所

affil-num=3
en-affil=
kn-affil=岡山大学三朝分院放射線室

affil-num=4
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=7
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=8
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=9
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=10
en-affil=
kn-affil=岡山大学三朝分院放射線室

affil-num=11
en-affil=
kn-affil=岡山大学第一内科

affil-num=12
en-affil=
kn-affil=岡山大学三朝分院内科
en-keyword=glucocorticoid
kn-keyword=glucocorticoid
en-keyword=cortical bone
kn-keyword=cortical bone
en-keyword=pQCT
kn-keyword=pQCT
en-keyword=osteoporosis
kn-keyword=osteoporosis
END

start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=
article-no=
start-page=42
end-page=49
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2001
dt-pub=20010201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=寒冷負荷の末梢循環に及ぼす影響
kn-title=Effect of partial cold-loading on peripheral circulation
en-subtitle=
kn-subtitle=
en-abstract=局所寒冷負荷の全身の末梢循環に及ぼす影響について検討する目的で，下肢の20℃冷水負荷時における上肢末梢循環の変化をレーザードプラー血流計を用いて数量的に測定し検討を行なった。症例は，下肢に冷え症，しびれ感を有した25歳から86歳までの24症例（平均年齢64.3歳）であった。下肢，上肢の末梢循環を20℃冷水負荷時に，末梢血流量，血液量，血流速度について観察した。上肢の末梢血流量は20℃室内安静時平均5.00mβ/min/100g tissue，血液量は287，血流速度は0.516であった。下肢は血流量2.23，血液量は149，血流速度は0.574であった。上肢の血流量，血液量ともに下肢より多いことが示された。しかし同一症例における上肢と下肢との間の血流量，血液量，血流速度に相関関係は認めなかった。下肢の20℃
冷水負荷中の上肢の血流量は平均3.69で有意に低下（26.2％）した。下肢はその間1．51で有意に低下（32.3％）した。上肢の血液量は平均241で有意に低下（16．0％）した。下肢はその間113で有
意に低下（24.2％）した。上肢の血流速度は平均0.501で不変であった。下肢はその間0．642で有意に増加（11.8％）した。冷水負荷直後よりそれぞれ負荷前に復帰する傾向を示した。負荷後20分では上肢の血流量は平均5．74で負荷前値に比べて増加（14.8％）傾向を示した。下肢は1.87で負荷前値に比べて低値（83.9％）に留まる傾向にあった。下肢の冷水負荷は上肢の末梢循環にも影響を及ぼすことが数量的に示された。局所の寒冷負荷による体温の低下を防ぐために反射的に全身の皮膚の末梢循環量を低下させていることが示された。
kn-abstract=The purpose of this study is the effect of partial cold-loading on whole body peripheral circulation. The body surface peripheral circulation in 24 cases (25 years old
to 86 years old, the average was 64.3 years) who were suffering coldness, numbness or pain in their feet was examined using Laser-Doppler blood flowmetry. The peripheral
circulation at the base of the 2nd toe of the right foot was estimated after the foot was submerged and cooled for 5 min in a water bath at 20°C (i. e. cold-loading). At the same time, the distant body surface peripheral circulation was estimated at the base of the 2nd finger of the right hand. Simultaneous observations were made of blood flow, blood mass and blood velocity. The peripheral blood flow of the upper
limbs at a room temperature of 20°C (pre-loading) was 5.00 ml/min 100 9 tissue on average. The average blood rnass was 287 and the average blood velocity was 0.516. On the other hand, the average peripheral blood flow of the lower limbs was 2.23, the average blood mass was 149 and the average blood velocity was 0.574. This result shows that the blood flow and blood mass of the upper limbs were more than in the
lower limbs. The average blood flow at the upper limbs decreased to 3.69 from 5.00 (or at 26.2% ) when the lower limbs were submerged and cooled for 5 min in a water
bath at 20°C (i. e. cold-loading). On the other hand, blood flow of the lower limb was 1.51 m l under a condition of cold-loading, and decreased 32.3% from 2.23. Blood mass
of the upper limb was 241 on average and decreased 16.0% from 287. Blood mass of the lower limb was 113 on average and decreased 24.2% from 149. There was no difference between blood velocity of the upper limb under the conditions of room
temperature at 20°C (0.516) and cold-loading (0.501). However, blood velocity of the lower limb increased to 0.642 from 0.574. After the end of cold loading, there was
some tendency for blood flow, blood rnass and blood velocity to return to the amount at pre-loading. Twenty minutes after the end of cold-loading, blood flow increased to 5.74 (14.8% ) compared with pre-loading (5.00). However, blood flow of the lower limb remained at only 83.9% (1.87) of the amount at pre-loading (2.23). These results show that partial cold-loading of the lower limb had a quantitative effect on the distant peripheral circulation. The speculated mechanism of this phenomenon is that it to protects against loosing body heat from the body surface under the conditions of
local cold-loading. Our body has defense mechanisms to decrease whole body peripheral circulation to protect against loosing body heat.
en-copyright=
kn-copyright=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保�ｱ泰弘
kn-aut-sei=保�ｱ
kn-aut-mei=泰弘
aut-affil-num=1
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=2
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=3
ORCID=

en-aut-name=AshidaKozo
en-aut-sei=Ashida
en-aut-mei=Kozo
kn-aut-name=芦田耕三
kn-aut-sei=芦田
kn-aut-mei=耕三
aut-affil-num=4
ORCID=

en-aut-name=TsugenoHirofumi
en-aut-sei=Tsugeno
en-aut-mei=Hirofumi
kn-aut-name=柘野浩史
kn-aut-sei=柘野
kn-aut-mei=浩史
aut-affil-num=5
ORCID=

en-aut-name=OkamotoMakoto
en-aut-sei=Okamoto
en-aut-mei=Makoto
kn-aut-name=岡本誠
kn-aut-sei=岡本
kn-aut-mei=誠
aut-affil-num=6
ORCID=

en-aut-name=TakataShingo
en-aut-sei=Takata
en-aut-mei=Shingo
kn-aut-name=高田真吾
kn-aut-sei=高田
kn-aut-mei=真吾
aut-affil-num=7
ORCID=

en-aut-name=YokoiTadashi
en-aut-sei=Yokoi
en-aut-mei=Tadashi
kn-aut-name=横井正
kn-aut-sei=横井
kn-aut-mei=正
aut-affil-num=8
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=9
ORCID=

en-aut-name=OchiKoji
en-aut-sei=Ochi
en-aut-mei=Koji
kn-aut-name=越智浩二
kn-aut-sei=越智
kn-aut-mei=浩二
aut-affil-num=10
ORCID=

en-aut-name=TsujiTakao
en-aut-sei=Tsuji
en-aut-mei=Takao
kn-aut-name=辻孝夫
kn-aut-sei=辻
kn-aut-mei=孝夫
aut-affil-num=11
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=7
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=8
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=9
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=10
en-affil=
kn-affil=医学部臨床検査医学

affil-num=11
en-affil=
kn-affil=医学部第一内科
en-keyword=Laser-Doppler blood flowmetry (レーザードプラー血流計)
kn-keyword=Laser-Doppler blood flowmetry (レーザードプラー血流計)
en-keyword=cold loading (冷水負荷)
kn-keyword=cold loading (冷水負荷)
en-keyword=peripheral circulation (末梢循環)
kn-keyword=peripheral circulation (末梢循環)
en-keyword=blood flow (血流量)
kn-keyword=blood flow (血流量)
en-keyword=blood velocity (血流速度)
kn-keyword=blood velocity (血流速度)
END

start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=
article-no=
start-page=29
end-page=35
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2001
dt-pub=20010201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=気管支喘息患者における肺機能とHRCT上のlow attenuation areaに対する喫煙の影響
kn-title=Correlation between pulmonary function and low attenuation area (LAA) on HRCT III patients with asthma in relation to smoking
en-subtitle=
kn-subtitle=
en-abstract=気管支喘息49例を対象に､肺機能およびHigh resolution computed tomography(HRCT)上のLow attenuation are (LAA) <-950HUで示される肺気腫様変化に及ぼす喫煙の影響について検討した｡　
1.気管支喘息患者のうち､非喫煙例では% 残気量(% RV)は多くの症例(65.6% )で129% 以下であったが､一方喫煙症例では130% から189% を示す症例が最も多く見られた(60.0% )｡非喫煙例および喫煙例いずれにおいても､
2.% RVと% LAA､% RVとCT number 間に有意の相関が見られた: % RVが上昇するにつれて､% LAA値は増加し､CT numberは低下する傾向が見られた｡　
3.喫煙例では､% RVが130-189% あるいは190% 以上の症例で､% DLco値
が明かに低値を示す症例が見られたが､非喫煙症例では% RVが高い値を示しても% DLcoの低下はみられなかった｡　
4.喫煙例､非喫煙例いずれにおいても､% FEV1.0倍と% RV値の問には有意の相関が見られ､% RV値が上昇するにつれて､% FEV1.0値は低下する傾向が見られた｡　
5.% FVCと% RVの問には相関は見られなかった｡以上の結果より､喫煙は気管支喘息患者のHRCT上の% LAAおよび% DLcoに影響を与えることが示唆された｡
kn-abstract=The influence of smoking on pulmonary function and emphysematous changes of the lung (percentage of attenuation area < -950 HU (% LAA) on high resolution computed tomography (HRCT) was examined in 49 patients with bronchial asthma.  
1. In patients with asthma, the % residual volume (RV) in many nonsmokers was less than 129%, in contrast, the % RV in many smokers was between 130% and 189% , which was higher than that in nonsmokers.  
2. Significant correlations between % RV and 96LAA value, and between % RV and CT number were observed both in
nonsmokers and smokers with asthma, in which as % RV more increased, % LAA value was larger, and CT number was lower.  
3. % DLco value was lower in smoking patients with asthma, whose % RV was between 130% and 189% and larger than 190% , however, the % DLco value did not change in nonsmoking patients despite of higher valure in % RV.  
4. A significant correlation was also observed between % FEV1.0 value and % RV both in smoking and nonsmoking patients with asthma; as % RV value more increased, % FEV1.0 value was lower.  
5. Any correlation between % FVC value and % RV was not observed. These results suggest that smoking affects the % LAA of the lung on HRCT and % DLco in patients with asthma.
en-copyright=
kn-copyright=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=1
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=2
ORCID=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保�ｱ泰弘
kn-aut-sei=保�ｱ
kn-aut-mei=泰弘
aut-affil-num=3
ORCID=

en-aut-name=AshidaKozo
en-aut-sei=Ashida
en-aut-mei=Kozo
kn-aut-name=芦田耕三
kn-aut-sei=芦田
kn-aut-mei=耕三
aut-affil-num=4
ORCID=

en-aut-name=TsugenoHirofumi
en-aut-sei=Tsugeno
en-aut-mei=Hirofumi
kn-aut-name=柘野浩史
kn-aut-sei=柘野
kn-aut-mei=浩史
aut-affil-num=5
ORCID=

en-aut-name=OkamotoMakoto
en-aut-sei=Okamoto
en-aut-mei=Makoto
kn-aut-name=岡本誠
kn-aut-sei=岡本
kn-aut-mei=誠
aut-affil-num=6
ORCID=

en-aut-name=TakadaShingo
en-aut-sei=Takada
en-aut-mei=Shingo
kn-aut-name=高田真吾
kn-aut-sei=高田
kn-aut-mei=真吾
aut-affil-num=7
ORCID=

en-aut-name=YokoiTadashi
en-aut-sei=Yokoi
en-aut-mei=Tadashi
kn-aut-name=横井正
kn-aut-sei=横井
kn-aut-mei=正
aut-affil-num=8
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=9
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=7
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=8
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=9
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科
en-keyword=asthma
kn-keyword=asthma
en-keyword=smoking
kn-keyword=smoking
en-keyword=% LAA of the lungs
kn-keyword=% LAA of the lungs
en-keyword=FEV1.0
kn-keyword=FEV1.0
en-keyword=DLco
kn-keyword=DLco
END

start-ver=1.4
cd-journal=joma
no-vol=72
cd-vols=
no-issue=
article-no=
start-page=74
end-page=79
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2002
dt-pub=20020201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=高齢者気管支喘息の病態におよぼす加齢および喫煙の影響について
en-subtitle=
kn-subtitle=
en-abstract=Influences of aging and cigarette smoking on the pathophysiology in elderly patients wish asthma were examined in 152 patients with asthma and 14 patients with pulmonary emphysema. The low attenuation area (LAA) <-950 HU of the lungs on high-resolution computed tomography (HRCT) was significantly larger in patients over age 70 years than in those under age 49 years. A significant increase in residual
volume (RV) of the lungs and significant decrease in the value of DLco were observed in these patients over age 70 compared to the values in those under age 49. A significant correlation between % LAA and % FEV1.0 was found in patients with asthma (in both smoker and nonsmoker) and with pulmonary emphysema. However, any correlation between % LAA and the
value of DLco was not observed in nonsmoking patients with asthma, suggesting that the influence of smoking on DLco is remarkably larger than the influence of aging.
kn-abstract=高齢者喘息の病態に対する加齢および喫煙の影響について,若干の検討を加えた｡高齢者喘息,特に70才以上の喘息では,HRCT上の1950HU以下の肺のlow attenuation area(LAA)は,苦青年者喘息と比べ有意に増加していた.また,同時にこの年齢層では残気量の有意の増加,拡散能の有意の低下が見られた.% LAAと% 1秒量との間には,喘息の非喫煙例,喫煙例,肺気腫(全例喫煙例),いずれにおいても相関が見られた｡しかし,% LAAと拡散能との間には,喘息の喫煙例および肺気腫では相関が見られたが,非喫煙例では有意の相関は見られなかった｡これは,喫煙の拡散能におよぽす影響が大きいことを示唆しているものと考えられた｡
en-copyright=
kn-copyright=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=1
ORCID=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保崎泰弘
kn-aut-sei=保崎
kn-aut-mei=泰弘
aut-affil-num=2
ORCID=

en-aut-name=AshidaKozo
en-aut-sei=Ashida
en-aut-mei=Kozo
kn-aut-name=芦田耕三
kn-aut-sei=芦田
kn-aut-mei=耕三
aut-affil-num=3
ORCID=

en-aut-name=TsugenoHirofumi
en-aut-sei=Tsugeno
en-aut-mei=Hirofumi
kn-aut-name=柘野浩史
kn-aut-sei=柘野
kn-aut-mei=浩史
aut-affil-num=4
ORCID=

en-aut-name=OkamotoMakoto
en-aut-sei=Okamoto
en-aut-mei=Makoto
kn-aut-name=岡本誠
kn-aut-sei=岡本
kn-aut-mei=誠
aut-affil-num=5
ORCID=

en-aut-name=NishidaNorikazu
en-aut-sei=Nishida
en-aut-mei=Norikazu
kn-aut-name=西田典数
kn-aut-sei=西田
kn-aut-mei=典数
aut-affil-num=6
ORCID=

en-aut-name=YokoiTadashi
en-aut-sei=Yokoi
en-aut-mei=Tadashi
kn-aut-name=横井正
kn-aut-sei=横井
kn-aut-mei=正
aut-affil-num=7
ORCID=

en-aut-name=TakataShingo
en-aut-sei=Takata
en-aut-mei=Shingo
kn-aut-name=高田真吾
kn-aut-sei=高田
kn-aut-mei=真吾
aut-affil-num=8
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=9
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=3
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=7
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=8
en-affil=
kn-affil=岡山大学三朝分院内科

affil-num=9
en-affil=
kn-affil=岡山大学三朝分院内科
en-keyword=高齢者喘息 (asthma in the elderly)
kn-keyword=高齢者喘息 (asthma in the elderly)
en-keyword=気腫化傾向 (emphysematous changes)
kn-keyword=気腫化傾向 (emphysematous changes)
en-keyword=HRCT
kn-keyword=HRCT
en-keyword=残気量 (residual volume)
kn-keyword=残気量 (residual volume)
en-keyword=DLco
kn-keyword=DLco
END

start-ver=1.4
cd-journal=joma
no-vol=72
cd-vols=
no-issue=
article-no=
start-page=31
end-page=37
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2002
dt-pub=20020201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Non-invasive study for peripheral circulation in patients with diabetes mellitus
en-subtitle=
kn-subtitle=
en-abstract=糖尿病患者における閉塞性動脈硬化症の合併を早期に診断,予知,予防する目的で末梢循環障害の程度を非侵襲的にかつ客観的に測定することを試みた｡非侵襲的測定方法としてサーモグラフィーとレ-ザードップラー血流計を同時に用い,得られた結果を数量化した｡症例は,下肢に冷え症,しびれ感,下肢痛を有した51歳から82歳までの
27症例(平均年齢67.4歳)であった｡性別は,男性14例,女性13例,HbA1Cは6.8%-13.0%,辛均9.5%であった｡サーモグラフィーで得られた結果は回復率として数量化して表示された｡回復率の算出方法は回復率-【20℃冷水負荷後の27℃以上の体表面温度のサーモグラフィーの画素(pixel)の総数】÷【36℃の温水負荷後の27℃以上の体表面温度のサーモグラフィーのPixelの総数】×100%で求めた｡
サ-モグラフィーにより測定された回復率は0%-93.5%の範囲にあった｡平均は34.0%であった｡レーザードップラー血流計により20℃冷水負荷後に測定された血流量は0.91-5.36ml/min/100g tissueの範囲にあった｡平均は2.04mi/min/100g tissueであった｡得られたサーモグラフィーの回復率とレ-ザードップラ-血流計の血流量との間には正の相関関係を認めた(p<0.0001,r=0.634)0 36℃の温水負荷後に測定された血流量とサーモグラフィーの回復率との間には20℃冷水負
荷後同様に相関関係(p-0.0002,r=0.483)を認めたが,相関係数は20℃冷水負荷後に比較して低値であった｡性別と回復率との間には男性28%,女性40%で女性の方が回復率が高い傾向にあったが,2群間に有意差を認めなっかた｡年齢と回復率の間には正の相関関係(p<0.0001,r=0.187)を認めたが相関係数は低値であった｡HbA1Cと回復率との間には正の相関関係(p<0.001,r=0.041)を認めたが相関係数は低値であった｡一方,性別と血流量との間には男性2.03,女性2.05ml/min/100g tissueで女性の方が血流量が多い傾向にあったが,2群間に有意差を認めなかった｡年齢と血流量との間には正の相関関係(p<0.0001,r=0.110)を認めたが相関係数は低値であった｡HbA1Cと血涜量との間には負の相関関係(p<0.0001,r=-0.179)を認めたが相関係数は低値であった｡36℃温水負荷時の血流量を100%とした時の20℃冷水負荷時の血流量の割合を求めたところ38.1%〜122%の範囲にあった｡
平均は80.6%であった｡冷水負荷後の血流量の温水負荷時との比と回復率との間には正の相関関係を認めた(p<0.0001,r=0.502)｡このことは,末梢血流量が冷水負荷後,速やかに冷水負荷前値に回復するか,あるいはさらに前値よりも上回って増加する症例においては末梢皮膚温度の回復率が高いことが示された｡
糖尿病患者における末梢循環障害の程度をサーモグラフィーとレーザ-ドップラー血流計を同時に用い非侵襲的にかつ客観的に測定することが可能であった｡今後,両者の併用は糖尿病患者における閉塞性動脈硬化症の合併の早期診断,予知,予防に役立つことのみならず,末梢循環障害の程度に応じた治療とその効果について定量的な評価に有用な方法と考えられた｡
kn-abstract=The purpose of this study is to establish a new, non - invasive diagnostic technique for peripheral circulation in patients with diabetes mellitus in the early stage of arteriosclerosis obliterans (ASO) as one of the complications of diabetes mellitus. We observed peripheral circulation quantitatively by thermography and Laser- Doppler blood flowmetry. The body surface peripheral circulation in 27 patients with diabetes mellitus, including 14 males and 13 females with a mean age of 67.4 years (range from 51-82 years), and with a mean hemoglobin A1C (HbA1C) 019.5% (range from 6.8%-13.0%), and who were suffering coldness, numbness or pain in their feet, was examined using thermography and Laser- Doppler blood flowmetry. Thermographic results
were analyzed quantitatively by calculating a recovery ratio as : Recovery ratio= [Total counts of thermography (Pixels) over temperature (T) after cold -loading] + [Initial counts over T after hot-loading] Xl00 (%). Results of recovery ratios for 27 cases were 0% - 93.5%, and the average was 34.0%. At the same time, the blood flow after cold -loading was 0.91 - 5. 36ml/min/lOOg tissue and the average was 2.04ml/min/l00g tissue. We found that the recovery ratio
and the blood flow were correlated (r=O. 634, p<O. 0001). The recovery ratio for males was 28.4% and that of females was 39.9%, and there was a tendency for the recovery ratio of females to be higher than males, however, this was not statistically significant. There was a correlation between the recovery ratio and age (r=O.187, p < 0.0001), although, the correlation was low. There was also a slight correlation between the recovery ratio and HbA1C (r=0.041, p<O.OOl). On the other hand, the blood flow of males was 2. 03ml/min/lOOg tissue and that of females was 2.05. There was a tendency for the recovery ratio of females to be higher than males.
however. the correlation was not significant. There was a correlation between blood flow and age (r=O. 110, p<0 . 0001) , however, the correlation was low. There was also a
slight negative correlation between blood flow and HbA1C (r=-0.179, p<O.OOOl). The ratio of the blood flow after cold -loading at 20t divided by the blood flow after hot -loading at 36 C was 38.1 %-122%, and the average was 80.6%. There was correlation between this ratio and the recovery ratio (r=0.502, p<O.OOOl). The case of the peripheral blood flow recovered immediately to the amount of the hot-loading or
access amount of hot-loading after cold-loading, and had a high recovery ratio of thermography. This might mean that the cooled body surface was warmed by overcirculation of blood flow to keep body temperature at 30C in the mean of homeostasis. We showed that thermography and Laser- Doppler blood flowmetry were useful for non - invasive study to separate patients with poor peripheral circulation. We recommend that these methods for evaluation of further treatment, such as with Prostaglandin E1, on peripheral circulation in patients with diabetes mellitus and ASO.
en-copyright=
kn-copyright=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保崎泰弘
kn-aut-sei=保崎
kn-aut-mei=泰弘
aut-affil-num=1
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=2
ORCID=

en-aut-name=AshidaKozo
en-aut-sei=Ashida
en-aut-mei=Kozo
kn-aut-name=芦田耕三
kn-aut-sei=芦田
kn-aut-mei=耕三
aut-affil-num=3
ORCID=

en-aut-name=TsugenoHirofumi
en-aut-sei=Tsugeno
en-aut-mei=Hirofumi
kn-aut-name=柘野浩史
kn-aut-sei=柘野
kn-aut-mei=浩史
aut-affil-num=4
ORCID=

en-aut-name=OkamotoMakoto
en-aut-sei=Okamoto
en-aut-mei=Makoto
kn-aut-name=岡本誠
kn-aut-sei=岡本
kn-aut-mei=誠
aut-affil-num=5
ORCID=

en-aut-name=NishidaNorikazu
en-aut-sei=Nishida
en-aut-mei=Norikazu
kn-aut-name=西田典教
kn-aut-sei=西田
kn-aut-mei=典教
aut-affil-num=6
ORCID=

en-aut-name=TakataShingo
en-aut-sei=Takata
en-aut-mei=Shingo
kn-aut-name=高田真吾
kn-aut-sei=高田
kn-aut-mei=真吾
aut-affil-num=7
ORCID=

en-aut-name=YokoiTadashi
en-aut-sei=Yokoi
en-aut-mei=Tadashi
kn-aut-name=横井正
kn-aut-sei=横井
kn-aut-mei=正
aut-affil-num=8
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=9
ORCID=

en-aut-name=OchiKoji
en-aut-sei=Ochi
en-aut-mei=Koji
kn-aut-name=越智浩二
kn-aut-sei=越智
kn-aut-mei=浩二
aut-affil-num=10
ORCID=

en-aut-name=TsujiTakao
en-aut-sei=Tsuji
en-aut-mei=Takao
kn-aut-name=辻孝夫
kn-aut-sei=辻
kn-aut-mei=孝夫
aut-affil-num=11
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=2
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=3
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=4
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=5
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=6
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=7
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=8
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=9
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=10
en-affil=
kn-affil=医学部臨床検査医学

affil-num=11
en-affil=
kn-affil=医学部第一内科
en-keyword=diabetes mellitus (糖尿病)
kn-keyword=diabetes mellitus (糖尿病)
en-keyword=peripheral circulation (末梢循環)
kn-keyword=peripheral circulation (末梢循環)
en-keyword=thermography (サーモグラフィー)
kn-keyword=thermography (サーモグラフィー)
en-keyword=Laser-Doppler blood flowmetry (レーザードプラー血流計)
kn-keyword=Laser-Doppler blood flowmetry (レーザードプラー血流計)
en-keyword=blood flow (血流量)
kn-keyword=blood flow (血流量)
END

start-ver=1.4
cd-journal=joma
no-vol=72
cd-vols=
no-issue=
article-no=
start-page=9
end-page=15
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2002
dt-pub=20020201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=HRCT上の肺のLow Attenuation Areaおよび肺機能により評価された高齢者善喘息の特徴
kn-title=% Low attenuation area (% LAA) of the lungs on high resolution computed tomography (HRCT), associated with pulmonary function in elderly patients with asthma
en-subtitle=
kn-subtitle=
en-abstract=気管支喘息80例(全例非喫煙者)を対象に,high resolution computedt omography (HRCT)上の肺の-950HU以下のLow attenuation area (LAA)の臨床的意義について, 患者年齢, CT number,残気率(% RV),拡散能(% DLco)を含む肺機能検査,白血球のコイコトリエンB4,C4の産生能などとの関連のもとに検討を加えた｡
1.% LAAは,年齢が高くなるにつれて増加する傾向を示し,60才以上の症例の% LAAは,49歳以下の症例に比べ有意に高い値を示した｡また,CT numberも,年齢が高くなるにつれて有意の増加を示した｡
2.% FVC,% FEV1.0およびFEV1.0%値は,いずれも70才以上の症例で49歳以下の症例に比べ有意に低い値を示した｡
3.残気率(% RV)は,年齢が高くなるにつれて増加する傾向を示し,70才以上の症例の% RVは,50-59才および49才以下の症例の% RVに比べ有意に高い値を示した｡
4.一方,拡散能(% DLco)は,年齢が高くなるにつれて有意に低下する傾向を示し,70才以上の症例の% DLcoは,50-59才および49才以下の症例のDLcoに比べ有意に低い値を示した｡
5.% LAAと% RVとの間には有意の相関が見られたが,% LAAと% DLco,および% LAAと換気機能(% FVC,% FEV1.0,FEV1.0%)との間には関連は見られなかった｡
6.白血球のLTB4およびLTC4の産生能においては年齢による差は見られなかった｡これらの結果は,% LAAが年齢とともに増加すること,そして% LAAは% RVと密接な関連を有していることを示している｡
kn-abstract=The clinical significance of low attenuation area <-950 HU of the lungs on high - resolution computed tomography (HRCT) was evaluated in 80 patients with asthma in relation to patient age, CT number, pulmonary function including % residusal volume (% RV) and % DLco, and generation of leukotrienes B4 and C4 by leucocytes. 
1. The % LAA (<- 950 HU) of the lungs showed a tendency to increase significantly with aging; the % LAA was significantly larger in elderly patients over the age of 60 years than in those under the age of 49 years. The CT number was also significantlyincreased with aging.
2. The values of % FVC, % FEV1.0, and FEV1.0% were
significantly decreased in elderly patients over age 70 compared with the values in those under age 49. 
3. The value of % residual volume (% RV) tended to increase significantly with aging; the value in patients over the age of 70 years was significantly larger in those between the ages of 50 and 59 (p<O.OOl). and under the age of 49
years (p<O.OOl). 4. The % DLco value significantly decreased with aging; the value in patients over age 70 was significantly lower than the value in those between the ages
of 50 and 59 (p<O.Ol) and under age 49 (p<O.OOl).
5. A significant correlation was observed between % LAA of the lungs and % RV (r=O. 67, p<0.001), however. any
significant correlations were not observed between % LAA and the values of % FVC, % FEV1.0, and FEV1.0% .
6. The generation of LTB4 and LTC4 by leucocytes was not
significantly related with patient age. The results suggested that % LAA of the lungs on HRCT tended to increse with
aging, accompanied with a significant increase in % RV.
en-copyright=
kn-copyright=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=1
ORCID=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保崎泰弘
kn-aut-sei=保崎
kn-aut-mei=泰弘
aut-affil-num=2
ORCID=

en-aut-name=AshidaKozo
en-aut-sei=Ashida
en-aut-mei=Kozo
kn-aut-name=芦田耕三
kn-aut-sei=芦田
kn-aut-mei=耕三
aut-affil-num=3
ORCID=

en-aut-name=TsugenoHirofumi
en-aut-sei=Tsugeno
en-aut-mei=Hirofumi
kn-aut-name=柘野浩史
kn-aut-sei=柘野
kn-aut-mei=浩史
aut-affil-num=4
ORCID=

en-aut-name=OkamotoMakoto
en-aut-sei=Okamoto
en-aut-mei=Makoto
kn-aut-name=岡本誠
kn-aut-sei=岡本
kn-aut-mei=誠
aut-affil-num=5
ORCID=

en-aut-name=NishidaNorikazu
en-aut-sei=Nishida
en-aut-mei=Norikazu
kn-aut-name=西田典教
kn-aut-sei=西田
kn-aut-mei=典教
aut-affil-num=6
ORCID=

en-aut-name=TakataShingo
en-aut-sei=Takata
en-aut-mei=Shingo
kn-aut-name=高田真吾
kn-aut-sei=高田
kn-aut-mei=真吾
aut-affil-num=7
ORCID=

en-aut-name=YokoiTadashi
en-aut-sei=Yokoi
en-aut-mei=Tadashi
kn-aut-name=横井正
kn-aut-sei=横井
kn-aut-mei=正
aut-affil-num=8
ORCID=

en-aut-name=NakaiMutsuo
en-aut-sei=Nakai
en-aut-mei=Mutsuo
kn-aut-name=中井睦郎
kn-aut-sei=中井
kn-aut-mei=睦郎
aut-affil-num=9
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=2
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=3
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=4
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=5
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=6
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=7
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=8
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=9
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院

affil-num=10
en-affil=
kn-affil=岡山大学医学部付属病院三朝分院
en-keyword=low attenuation area of the lung
kn-keyword=low attenuation area of the lung
en-keyword=CT number
kn-keyword=CT number
en-keyword=residual volume
kn-keyword=residual volume
en-keyword=DLco
kn-keyword=DLco
en-keyword=aging
kn-keyword=aging
END

start-ver=1.4
cd-journal=joma
no-vol=74
cd-vols=
no-issue=
article-no=
start-page=62
end-page=67
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2004
dt-pub=20040201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Emphysematous changes of the lungs in asthmatics in the elderly. Differences between hyperinflation of the lungs by aging and pulmonary emphysema
kn-title=高齢者喘息における気腫化傾向 - 加齢変化と病的変化（肺気腫）の相違点
en-subtitle=
kn-subtitle=
en-abstract=?Pathophysiological changes by aging were examined in asthmatics in the elderly. 
1 . A level of serum IgE and frequency of positive RAST score
for allergens were in general low. However, the frequency of patients with family history of allergic diseases was considerably high, and in these patients with family history having allergic diseases the presence of IgE-mediated allergic reaction was frequently observed. 
2 . Bronchial hyperresponsiveness tended to decrease with
aging. 
3 . Ventilatory function and gas exchange (DLco) showed a decrease with aging, and the decrease in ventilatory function and DLco in older patients over age 70 was significantly
lower than the decrease in younger patients with asthma under age 49. 
4 . The volume of the lungs, evaluated by % residual volume (% RV) , tended to increase with aging. The low attenuation
area (LAA) of the lungs < -950 HU on HRCT, which represents hyperinflation in asthma, was also increased with aging. A significant correlation was found between % RV and % LAA of
the lungs <-950HU on HRCT in patients over age 70.
kn-abstract=高齢者喘息の病態的特徴を臨床的に観察した。その結果は以下のごとくであった。
1．血清IgE値や抗原に対するIgE抗体の陽性率は一般的に低いが，しかしアレルギー疾患の家族歴を有する症例の頻度は高く，アトピー性の素因を有する症例の頻度がかなり高いこと，そして，このような症例ではIgE系反応の関与が示唆された。　
2．気道過敏性は加齢とともに低下する傾向が見られた。　
3．換気機能，ガス交換能は加齢とともに低下し，特に70才以上
の症例では若青年者喘息と比べ有意の低下が見られた。　
4．肺容積は，加齢とともに増大し，70才以上の症例では有意の増大傾向が見られた。また，この肺容積の増大は，HRCT上の−950HU以下の肺% UIAと有意の相関が見られ，肺の過膨張の状態が存在することが示唆された。
en-copyright=
kn-copyright=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光廷文裕
kn-aut-sei=光廷
kn-aut-mei=文裕
aut-affil-num=1
ORCID=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保崎泰弘
kn-aut-sei=保崎
kn-aut-mei=泰弘
aut-affil-num=2
ORCID=

en-aut-name=AshidaKozo
en-aut-sei=Ashida
en-aut-mei=Kozo
kn-aut-name=芦田耕三
kn-aut-sei=芦田
kn-aut-mei=耕三
aut-affil-num=3
ORCID=

en-aut-name=IwagakiNaofumi
en-aut-sei=Iwagaki
en-aut-mei=Naofumi
kn-aut-name=岩垣尚史
kn-aut-sei=岩垣
kn-aut-mei=尚史
aut-affil-num=4
ORCID=

en-aut-name=NagataTakuya
en-aut-sei=Nagata
en-aut-mei=Takuya
kn-aut-name=永田拓也
kn-aut-sei=永田
kn-aut-mei=拓也
aut-affil-num=5
ORCID=

en-aut-name=FujiiMakoto
en-aut-sei=Fujii
en-aut-mei=Makoto
kn-aut-name=藤井誠
kn-aut-sei=藤井
kn-aut-mei=誠
aut-affil-num=6
ORCID=

en-aut-name=TakataShingo
en-aut-sei=Takata
en-aut-mei=Shingo
kn-aut-name=高田真吾
kn-aut-sei=高田
kn-aut-mei=真吾
aut-affil-num=7
ORCID=

en-aut-name=YokoiTadashi
en-aut-sei=Yokoi
en-aut-mei=Tadashi
kn-aut-name=横井正
kn-aut-sei=横井
kn-aut-mei=正
aut-affil-num=8
ORCID=

en-aut-name=HamadaMasanori
en-aut-sei=Hamada
en-aut-mei=Masanori
kn-aut-name=浜田全紀
kn-aut-sei=浜田
kn-aut-mei=全紀
aut-affil-num=9
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=?岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=3
en-affil=
kn-affil=岡山大学医学部・学部附属病院三朝医療センター 内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部・学部附属病院三朝医療センター 内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=7
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター リハビリテーション科

affil-num=8
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター リハビリテーション科

affil-num=9
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=10
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科
en-keyword=lgE系反応 (IgE-mediated allergy)
kn-keyword=lgE系反応 (IgE-mediated allergy)
en-keyword=気道過敏性 (bronchial hyperresponsiveness)
kn-keyword=気道過敏性 (bronchial hyperresponsiveness)
en-keyword=換気機能 (ventilatory function)
kn-keyword=換気機能 (ventilatory function)
en-keyword=ガス交換能 (gas exchange)
kn-keyword=ガス交換能 (gas exchange)
en-keyword=気腫化傾向 (emphysematous changes)
kn-keyword=気腫化傾向 (emphysematous changes)
END

start-ver=1.4
cd-journal=joma
no-vol=74
cd-vols=
no-issue=
article-no=
start-page=42
end-page=47
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2004
dt-pub=20040201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=IgE系アレルギー反応はアトピー型気管支喘息の白血球ロイコトリエンB4（LTB4）およびC4（LTC4）産生を促進させ，喫煙は気道過敏性を亢進させる
kn-title=IgE-mediated allergy and cigarette smoking enhancethe generation of leukotrienes B4 (LTB4) and C4 (LTC4) by leucocytes and bronchial hyperresponsiveness in patients with atopic asthma
en-subtitle=
kn-subtitle=
en-abstract=ハウスダストあるいカンジダ抗原に対して特異的IgE抗体が陽性を示す気管支喘息69例を対象に，IgE系反応と喫煙の，気道過敏性および白血球のLTB4,LTC4産生に対する影響について検討を加えた。　
1．気道過敏性は，非喫煙者に比べ喫煙者でより高度であることが明らかにされた。　
2．白血球のLTC4，LVC4産生は，血清IgE値が351単位/ml以上の非喫煙症例で150単位以下および151−350単位/mlの症例に比べ有意に高い値を示した（m4：p＜0．01，LTC4：p＜0．05）。 
3．長期間の副腎皮質ホルモン投与は，LTC4産生を抑制したが，気道過敏性およびLTB4産生には影響しなかった。 
4．今回のようなアトピー型喘息では，気道過敏性と年令の間には有意の相関は見られなかった。以上の結果より，アトピー喘息では，IgE系反応は白血球のLTB4，LTC4産生を促進させ，また喫煙は気道過敏性を促進させることが明らかになった。
kn-abstract=Influences of IgE-mediated allergy and cigarette smoking on pathophysiology, evaluated by bronchial hyperresponsiveness and the generation of LTB4 and LTC4, of asthma were examined in 69 patients with asthma sensitive to inhalant allergens such as house dust mite and Candida albicans.
1 . Bronchial byperresponsiveness was significantly higher in previous and current smokers of asthmatics than in never-smokers. 2 . The generation of leukotrienes 84 (LTB4) and C4 (LTC4) by leucocytes was significantly larger in patients with serum IgE over 350 IU/ml than in those with serum IgE less than 150 IU/ml (LTB4 : p<O. 01 , LTC4 : p<0.05) . 3 . Long term glucocorticoid regimen suppressed the generation of LTC4, but not bronchial hyperresponsiveness and LTB4 generation. 4 . Bronchial
hyperresponsiveness was not significantly correlated with patient age in thse patients with atopic asthma. The results demonstrate that IgE-mediated allergy significantly enhances the generation of LTB4 and LRC4 by leucocytes, and cigarette smoking significantly enhances bronchial hyperresponsiveness in patients with atopic asthma.
en-copyright=
kn-copyright=

en-aut-name=AshidaKozo
en-aut-sei=Ashida
en-aut-mei=Kozo
kn-aut-name=芦田耕三
kn-aut-sei=芦田
kn-aut-mei=耕三
aut-affil-num=1
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光廷文裕
kn-aut-sei=光廷
kn-aut-mei=文裕
aut-affil-num=2
ORCID=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保崎泰弘
kn-aut-sei=保崎
kn-aut-mei=泰弘
aut-affil-num=3
ORCID=

en-aut-name=IwagakiNaofumi
en-aut-sei=Iwagaki
en-aut-mei=Naofumi
kn-aut-name=岩垣尚史
kn-aut-sei=岩垣
kn-aut-mei=尚史
aut-affil-num=4
ORCID=

en-aut-name=NagataTakuya
en-aut-sei=Nagata
en-aut-mei=Takuya
kn-aut-name=永田拓也
kn-aut-sei=永田
kn-aut-mei=拓也
aut-affil-num=5
ORCID=

en-aut-name=FujiiMakoto
en-aut-sei=Fujii
en-aut-mei=Makoto
kn-aut-name=藤井誠
kn-aut-sei=藤井
kn-aut-mei=誠
aut-affil-num=6
ORCID=

en-aut-name=TakataShingo
en-aut-sei=Takata
en-aut-mei=Shingo
kn-aut-name=高田真吾
kn-aut-sei=高田
kn-aut-mei=真吾
aut-affil-num=7
ORCID=

en-aut-name=YokoiTadashi
en-aut-sei=Yokoi
en-aut-mei=Tadashi
kn-aut-name=横井正
kn-aut-sei=横井
kn-aut-mei=正
aut-affil-num=8
ORCID=

en-aut-name=HamadaMasanori
en-aut-sei=Hamada
en-aut-mei=Masanori
kn-aut-name=浜田全紀
kn-aut-sei=浜田
kn-aut-mei=全紀
aut-affil-num=9
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部・学部附属病院三朝医療センター 内科

affil-num=2
en-affil=
kn-affil=?岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=3
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部・学部附属病院三朝医療センター 内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=7
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター リハビリテーション科

affil-num=8
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター リハビリテーション科

affil-num=9
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=10
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科
en-keyword=lgE-mediated allergy
kn-keyword=lgE-mediated allergy
en-keyword=bronchial hyperresponsiveness
kn-keyword=bronchial hyperresponsiveness
en-keyword=LTB4
kn-keyword=LTB4
en-keyword=LTC4
kn-keyword=LTC4
en-keyword=asthma
kn-keyword=asthma
en-keyword=cigarette smoking
kn-keyword=cigarette smoking
END

start-ver=1.4
cd-journal=joma
no-vol=74
cd-vols=
no-issue=
article-no=
start-page=18
end-page=25
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2004
dt-pub=20040201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=長期間の喫煙は高齢者気管支喘息における気道過敏性と関連した白血球LTB4産生を亢進させる
kn-title=Cigarette smoking enhances LTB4 generation by leucocytes associated with bronchial hyperresponsiveness in asthma in the elderly
en-subtitle=
kn-subtitle=
en-abstract=?気管支喘息110例を対象に，長期間の喫煙の気道過敏性および白血球のロイコトリエンB4産生に及ぼす影響について検討した。　
1．吸入抗原に対してRAST陽性を示す症例の頻度および白血球のLTB4産生は，喫煙例において非喫煙例に比べ有意に高い値を示した。　
2．非喫煙例においては、その気道過敏性は49才以下の症例において50−59才，60−69才および70才以上の症例に比べ，有意に高い値を示した。しかし，喫煙例においては，年令による気道過敏性の差は見られなかった。　
3．60才以上の症例では，その気道過敏性は非喫煙例に比べ，喫煙例で有意に高い値を示した。このような症例では，LTB4産生能も非喫煙例に比べ喫煙例で有意の亢進が見られた。　
4．非喫煙例では，気道過敏性とLTB4産生との間に有意の相関が見
られた。以上の結果より，60才以上の症例では喫煙がLTB4産生を克進させ，その結果として気道過敏性が亢進してくることが推測された。
kn-abstract=Abstract : Influence of cigarette smoking on leukotriene 84 (LTB4) generation by leucocytes associated with bronchial hyperresponsiveness was examined in 110 patients with asthma. l. The frequency of positive RAST score for inhalant allergens and LTB4 generation by leucocytes were significantly larger in previous and current smokers than in nonsmokers. 2. In nonsmokers, bronchial hyperresponsiveness was significantly higher in asthmatics under the age of 49 years compared with that in patients between 50 and 59 years, between 60 and 69 years, and those over age 70 years. In
contrast, no significant differences were present between bronchial hyperresponsiveness and patient age in previous and current smokers. 3. In patients over age 60, bronchial hyperresponsiveness was significantly higher in previous and current smokers than in nonsmokers. In these patients, LTB4 generation was significantly more increased in previous and current smokers than in nonsmokers. 4. A significant
correlation was observed in asthmatics of nonsmokers between LTB4 generation and bronchial hyperresponsiveness . 5. LTC4 generation was significantly higher in previous and current smokers than in nonsmokers in patients under age 49 years.
These results show that in patients over age 60 years, cigarette smoking induces an increase in the generation of LTB4, leading to an increase in bronchial hyperresponsiveness
.
en-copyright=
kn-copyright=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=光廷文裕
kn-aut-sei=光廷
kn-aut-mei=文裕
aut-affil-num=1
ORCID=

en-aut-name=HosakiYasuhiro
en-aut-sei=Hosaki
en-aut-mei=Yasuhiro
kn-aut-name=保崎泰弘
kn-aut-sei=保崎
kn-aut-mei=泰弘
aut-affil-num=2
ORCID=

en-aut-name=AshidaKozo
en-aut-sei=Ashida
en-aut-mei=Kozo
kn-aut-name=芦田耕三
kn-aut-sei=芦田
kn-aut-mei=耕三
aut-affil-num=3
ORCID=

en-aut-name=IwagakiNaofumi
en-aut-sei=Iwagaki
en-aut-mei=Naofumi
kn-aut-name=岩垣尚史
kn-aut-sei=岩垣
kn-aut-mei=尚史
aut-affil-num=4
ORCID=

en-aut-name=NagataTakuya
en-aut-sei=Nagata
en-aut-mei=Takuya
kn-aut-name=永田拓也
kn-aut-sei=永田
kn-aut-mei=拓也
aut-affil-num=5
ORCID=

en-aut-name=FujiiMakoto
en-aut-sei=Fujii
en-aut-mei=Makoto
kn-aut-name=藤井誠
kn-aut-sei=藤井
kn-aut-mei=誠
aut-affil-num=6
ORCID=

en-aut-name=TakataShingo
en-aut-sei=Takata
en-aut-mei=Shingo
kn-aut-name=高田真吾
kn-aut-sei=高田
kn-aut-mei=真吾
aut-affil-num=7
ORCID=

en-aut-name=YokoiTadashi
en-aut-sei=Yokoi
en-aut-mei=Tadashi
kn-aut-name=横井正
kn-aut-sei=横井
kn-aut-mei=正
aut-affil-num=8
ORCID=

en-aut-name=HamadaMasanori
en-aut-sei=Hamada
en-aut-mei=Masanori
kn-aut-name=浜田全紀
kn-aut-sei=浜田
kn-aut-mei=全紀
aut-affil-num=9
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=?岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=3
en-affil=
kn-affil=岡山大学医学部・学部附属病院三朝医療センター 内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部・学部附属病院三朝医療センター 内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=7
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター リハビリテーション科

affil-num=8
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター リハビリテーション科

affil-num=9
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科

affil-num=10
en-affil=
kn-affil=岡山大学医学部・歯学部附属病院三朝医療センター 内科
en-keyword=cigarette smoking
kn-keyword=cigarette smoking
en-keyword=asthma
kn-keyword=asthma
en-keyword=LTB4 generation
kn-keyword=LTB4 generation
en-keyword=LTC4 generation
kn-keyword=LTC4 generation
en-keyword=bronchial hyperresponsiveness
kn-keyword=bronchial hyperresponsiveness
END

start-ver=1.4
cd-journal=joma
no-vol=103
cd-vols=
no-issue=11-12
article-no=
start-page=1287
end-page=1299
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1991
dt-pub=1991
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Nutritional effects of branched chain amino acids and lipids in surgical stress after partial hepatectomy in the rat
kn-title=高濃度分岐鎖アミノ酸を窒素源とする成分栄養剤の侵襲下における効果―肝切除ラットを用いて―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The nutritional influence of branched chain amino acids (BCAA) and lipids in surgical stress was examined after 70% hepatectomy in rats. Two types of elemental diet (ED) were given through the gastrostomy tude for 7 days. Group A : ED containing 33% BCAA and 30% lipid (medium chain triglycerides 8.5g＋soy bean oil 1.5g/300 kcal). Group B : ED containing 17% BCAA and 1.5% lipid (soy bean oil 0.49g/300 kcal). Up to the 7th postoperative day, the excretion of nitrogen into urine decreased in group A, but no change occurred in group B. Up to the 5th postoperative day, molar ratio of 3MH to creatinine in urine in group A decreased more rapidly than in group B. Plasma concentration of albumin in group A was higher than in group B on the 7th postoperative day. Fischer ratio was significantly higher in group A than in group B on the 7th postoperative day. Both plasma and muscle levels of Tyr, Met and Gln were higher in group B than in group A, Glu and Ala were lower in group B than in group A. Essential fatty acid deficiency occurred more severely in group B than in group A. While fatty livers were microscopically observed in some livers in group B, there were few fatty deposits in group A.
en-copyright=
kn-copyright=

en-aut-name=MizutaMinoru
en-aut-sei=Mizuta
en-aut-mei=Minoru
kn-aut-name=水田稔
kn-aut-sei=水田
kn-aut-mei=稔
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第二外科学教室
en-keyword=分岐鎖アミノ酸
kn-keyword=分岐鎖アミノ酸
en-keyword=脂肪乳剤
kn-keyword=脂肪乳剤
en-keyword=経腸栄養
kn-keyword=経腸栄養
en-keyword=脂肪肝
kn-keyword=脂肪肝
END

start-ver=1.4
cd-journal=joma
no-vol=102
cd-vols=
no-issue=1-2
article-no=
start-page=143
end-page=152
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1990
dt-pub=199002
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Integration and expression of E1 region DNA in human adenovirus type 12-induced tumors
kn-title=ヒトアデノウィルス12型誘発腫瘍におけるE1領域遺伝子の組み込みと発現
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Integration and expression of human adenovirus type 12 (Ad12) were studied on two Ad12-induced tumor lines of C3Hf/OK mouse origin (IC and D tumors). Southern hybridization using whole Ad12 genome as probe demonstrated that DNA of IC and D tumors contained about 9 and 23 copies, respectively, of the entire Ad12 genome eqivalent per diploid cell. Left ends of Ad12 DNA appeared as off-size bands, indicating their linkage to different cellular DNAs. Southern hybridization using and Ad12 EcoRI-C fragment containing the E1 region as a probe revealed that intergration sites were much fewer than presumen numbers of integrated Ad12 genones. These results suggested that the viral and cellular DNA complex was repeated at integration sites. Northen hybridization using an Ad12 EcoRI-C fragment as a probe showed that tha E1 region was transcribed in both IC and D tumors. Much more intensive expression in the D tumor suggested possible dependence of the expression of the E1 region on the copy numbers of Ad12 genomes.
en-copyright=
kn-copyright=

en-aut-name=MorikawaTomoko
en-aut-sei=Morikawa
en-aut-mei=Tomoko
kn-aut-name=森川智子
kn-aut-sei=森川
kn-aut-mei=智子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=香川医科大学病理学講座第一病理学
en-keyword=ヒトアデノウィルス12型
kn-keyword=ヒトアデノウィルス12型
en-keyword=E1領域
kn-keyword=E1領域
en-keyword=C3Hf/OK マウス
kn-keyword=C3Hf/OK マウス
en-keyword=ウィルス発癌
kn-keyword=ウィルス発癌
END

start-ver=1.4
cd-journal=joma
no-vol=103
cd-vols=
no-issue=4
article-no=
start-page=387
end-page=397
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1991
dt-pub=1991
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the lymphocyte function bronchial asthma Part 1. Examination of lymphocyte responsiveness with inhalation antigens of bronchial asthma
kn-title=気管支喘息におけるリンパ球機能に関する研究 第1編 気管支喘息におけるBAL 液中並びに末梢血中リンパ球の吸入抗原に対する幼若化反応の検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Various antigens such as mite and fungi have been known to provoke bronchoconstriction in patients with bronchial asthma. The allergic mechanisms of asthmatic attack induced by these antigens were analyzed to clarify the role of cellular immunity in the pathogenesis of bronchial asthma. Mite and Candida antigens were applied to lymphocyte blastogenesis in asthmatic patients. Both lymphocytes in bronchoalveolar lavage fluid (BALF) and in peripheral blood of asthmatic patients responded significantly to mite and Candida antiten. Furthermore, BALF lymphocytes of patients with non-atopic and intractable asthma showed higher responses against Candida antigen than those of patients with atopic and non-intractable asthma, while peripheral blood lymphocytes showed a higher response against mite antigen in patients with atopic and non-intractable asthma. These findings indicate that lymphocytes in lugns sensitized with Candida antigen might play an important role in the pathogenesis of non-atopic and intractable asthma.
en-copyright=
kn-copyright=

en-aut-name=TakadaSho
en-aut-sei=Takada
en-aut-mei=Sho
kn-aut-name=武田昌
kn-aut-sei=武田
kn-aut-mei=昌
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第二内科学教室
en-keyword=気管支喘息
kn-keyword=気管支喘息
en-keyword=リンパ球幼若化反応
kn-keyword=リンパ球幼若化反応
en-keyword=bronchoalveolar lavage
kn-keyword=bronchoalveolar lavage
en-keyword=Candida
kn-keyword=Candida
en-keyword=mite
kn-keyword=mite
END

start-ver=1.4
cd-journal=joma
no-vol=103
cd-vols=
no-issue=1-2
article-no=
start-page=173
end-page=181
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1991
dt-pub=1991
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effects of heparin-urokinase on the brain damage induced by complete global brain ischemia
kn-title=完全全脳虚血後の脳障害に対するへパリン・ウロキナーゼ併用療法の効果に関する実験的研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The effect of heparin-urokinase (H-U) on the prevention of brain damage induced by ischemia was evaluated in 31 dogs subjected to an 18 min of complete global brain ischemia. Complete brain ischemia was produced by clamping the ascending aorta with aorto-atrial and aorto-femoral bypass formation. Post-ischemic cerebral blood flow (CBF) and other hemodynamic parameters were measured for 7 hours after ischemia in 15 dogs (acute study). Neurologic outcome was evaluated for 7 days after ischemia in 16 dogs (chronic study). Fifteen minutes after restoration of circulation to the brain, an intravenous bolus of heparin 100 I.U./kg and urokinase 3000 I.U./kg, was given, followed by continuous intravenous infusion of heparin 0.25 I.U./kg/min and urokinase 8.3 I.U./kg/min for 6 hours. H-U significantly improved both post-ischemic CBF and neurologic outcome. H-U was effective in treating brain damage when given 15 min after ischemia. These results suggest that H-U improved both post ischemic CBF and neurologic outcome owing to amelioration of the deterioration of microcirculation.
en-copyright=
kn-copyright=

en-aut-name=MorimotoNaoki
en-aut-sei=Morimoto
en-aut-mei=Naoki
kn-aut-name=森本直樹
kn-aut-sei=森本
kn-aut-mei=直樹
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部麻酔・蘇生学教室
en-keyword=完全全脳虚血
kn-keyword=完全全脳虚血
en-keyword=へパリン
kn-keyword=へパリン
en-keyword=ウロキナーゼ
kn-keyword=ウロキナーゼ
en-keyword=No-reflow 現象
kn-keyword=No-reflow 現象
en-keyword=遅発性脳血流減少
kn-keyword=遅発性脳血流減少
END

start-ver=1.4
cd-journal=joma
no-vol=98
cd-vols=
no-issue=1
article-no=
start-page=9
end-page=16
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2009
dt-pub=200902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Estimation of Completion of Dormancy in Grapevine Bud Based on Cumulative Temperature
kn-title=積算温度によるブドウの芽の休眠完了予測
en-subtitle=
kn-subtitle=
en-abstract=ブドウの芽の休眠完了と温度との関係を調査するため，温度条件の異なる７園（中信農試，山梨果試，岡山農試，岡山農試北部支場，岡山大学，福岡農試および宮崎）で栽培されている‘巨峰’と‘ピオーネ’から低温遭遇量の異なる３時期（12月，１月，２月）に結果母枝を採取した．直ちに岡山大学に送り，１芽を持つ挿し穂に調整した後，25または30℃のインキュベーター（14時間日長）に入れ，２日間隔で60日間発芽を調査した．処理開始時の7.2℃以下の遭遇量は中信農試で最も多く，次いで岡山農試北部支場，山梨果試，岡山農試，岡山大学，福岡農試，宮崎の順で，中信農試と宮崎では処理時期により2.5〜4.8倍の差があった．発芽所要日数は，両品種とも処理時期が遅いほど，また温度が高いほど少なく，60％発芽所要日数もほぼ同様の傾向であった．‘巨峰’の発芽所用日数は中信農試，岡山大学および宮崎で少ない一方，岡山農試，山梨果試および福岡農試で多く，また‘ピオーネ’では福岡農試と岡山大学で少なく，山梨果試と岡山農試で多かった．７園のうち４園で低温遭遇量と発芽所要日数との間に負の相関がみられたが，相関係数は低かった．一方，11月以降処理開始までの０℃以上の温度の積算値と処理開始から発芽までの25または30℃での積算値を合計した積算温度と発芽所要日数との間には１園を除き極めて高い正の相関が認められた．これらの結果を基に，積算温度によるブドウの休眠完了予測の可能性を考察した．
kn-abstract=　This study was conducted to investigate the relationship between completion of dormancy of grapevine
bud and temperature. Canes of ‘Kyoho’ and ‘Pione’ grapevines (Vitis labrusca×V. vinifera) grown in 7 vineyards with different temperature conditions, in Nagano, Northern Okayama, Yamanashi, Okayama, Okayama University, Fukuoka and Miyazaki, were collected at three different chilling exposures,
December, January and February. These were then sent to Okayama University all at the same time. Cuttings with one bud were put into growth chambers kept at 25 or 30°C with 14 hours daylength, and budbreak in each cutting was surveyed at two day intervals for 60 days. Cumulative chilling hours (CCH) of exposure to below 7.2°C in each treatment time was largest in Nagano, followed in order by Northern Okayama, Yamanashi, Okayama, Okayama University, Fukuoka and Miyazaki. The CCH in Nagano was 2.5 to 4.8 times larger than in Miyazaki depending on the treatment time. The later the treatment time and the higher the temperature, the fewer were the number of days to first budbreak (NDFB) after treatment, irrespective of cultivar. A similar trend was observed in the number of days to 60% budbreak. In ‘Kyoho’ the NDFB was short in Nagano, Okayama University and Miyazaki, and longer in Okayama, Yamanashi and Fukuoka. In ‘Pione’ the NDFB was short in Fukuoka and Okayama University, and longer in Yamanashi and Okayama. The result was a weak negative correlation observed between CCH and NDFB in 4 of 7 vineyards. However, there was a strong positive correlation between NDFB and cumulative temperature (CT), a summation of temperature and hours of exposure to above 0°C from November 1 to treatment time and hours of exposure to 25 or 30°C from start of treatment to budbreak in each plot, in 6 vineyards excluding Miyazaki. The importance of estimating the completion of dormancy in grapevine bud based on CT is discussed.
en-copyright=
kn-copyright=

en-aut-name=KubotaNaohiro
en-aut-sei=Kubota
en-aut-mei=Naohiro
kn-aut-name=久保田尚浩
kn-aut-sei=久保田
kn-aut-mei=尚浩
aut-affil-num=1
ORCID=

en-aut-name=PotjanapimonChaiwat
en-aut-sei=Potjanapimon
en-aut-mei=Chaiwat
kn-aut-name=ポジャナピモンチャイワット
kn-aut-sei=ポジャナピモン
kn-aut-mei=チャイワット
aut-affil-num=2
ORCID=

en-aut-name=FukudaFumio
en-aut-sei=Fukuda
en-aut-mei=Fumio
kn-aut-name=福田文夫
kn-aut-sei=福田
kn-aut-mei=文夫
aut-affil-num=3
ORCID=

en-aut-name=FujiiaYuichiro
en-aut-sei=Fujiia
en-aut-mei=Yuichiro
kn-aut-name=藤井雄一郎
kn-aut-sei=藤井
kn-aut-mei=雄一郎
aut-affil-num=4
ORCID=

en-aut-name=OnoToshiro
en-aut-sei=Ono
en-aut-mei=Toshiro
kn-aut-name=小野俊朗
kn-aut-sei=小野
kn-aut-mei=俊朗
aut-affil-num=5
ORCID=

en-aut-name=KurafujiYuki
en-aut-sei=Kurafuji
en-aut-mei=Yuki
kn-aut-name=倉藤祐輝
kn-aut-sei=倉藤
kn-aut-mei=祐輝
aut-affil-num=6
ORCID=

en-aut-name=OgoroAtsuo
en-aut-sei=Ogoro
en-aut-mei=Atsuo
kn-aut-name=尾頃敦郎
kn-aut-sei=尾頃
kn-aut-mei=敦郎
aut-affil-num=7
ORCID=

en-aut-name=KunugiYukihiro
en-aut-sei=Kunugi
en-aut-mei=Yukihiro
kn-aut-name=功刀幸博
kn-aut-sei=功刀
kn-aut-mei=幸博
aut-affil-num=8
ORCID=

en-aut-name=KobayashiKazushi
en-aut-sei=Kobayashi
en-aut-mei=Kazushi
kn-aut-name=小林和司
kn-aut-sei=小林
kn-aut-mei=和司
aut-affil-num=9
ORCID=

en-aut-name=ShigeharaIzumi
en-aut-sei=Shigehara
en-aut-mei=Izumi
kn-aut-name=茂原泉
kn-aut-sei=茂原
kn-aut-mei=泉
aut-affil-num=10
ORCID=

en-aut-name=YamashitaHiroyuki
en-aut-sei=Yamashita
en-aut-mei=Hiroyuki
kn-aut-name=山下裕之
kn-aut-sei=山下
kn-aut-mei=裕之
aut-affil-num=11
ORCID=

en-aut-name=FujishimaHiroyuki
en-aut-sei=Fujishima
en-aut-mei=Hiroyuki
kn-aut-name=藤島宏之
kn-aut-sei=藤島
kn-aut-mei=宏之
aut-affil-num=12
ORCID=

affil-num=1
en-affil=
kn-affil=応用植物科学コース

affil-num=2
en-affil=
kn-affil=応用植物科学コース

affil-num=3
en-affil=
kn-affil=応用植物科学コース

affil-num=4
en-affil=
kn-affil=岡山県農業総合センター農業試験場

affil-num=5
en-affil=
kn-affil=岡山県農業総合センター農業試験場

affil-num=6
en-affil=
kn-affil=岡山県農業総合センター農業試験場

affil-num=7
en-affil=
kn-affil=岡山県農業総合センター農業試験場

affil-num=8
en-affil=
kn-affil=山梨県果樹試験場

affil-num=9
en-affil=
kn-affil=山梨県果樹試験場

affil-num=10
en-affil=
kn-affil=長野県中信農業試験場

affil-num=11
en-affil=
kn-affil=長野県中信農業試験場

affil-num=12
en-affil=
kn-affil=福岡県農業総合試験場
en-keyword=budbreak
kn-keyword=budbreak
en-keyword=chilling exposure
kn-keyword=chilling exposure
en-keyword=growing region
kn-keyword=growing region
en-keyword=temperature condition
kn-keyword=temperature condition
en-keyword=Vitis labrusca × V. vinifera
kn-keyword=Vitis labrusca × V. vinifera
END

start-ver=1.4
cd-journal=joma
no-vol=103
cd-vols=
no-issue=1-2
article-no=
start-page=53
end-page=63
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1991
dt-pub=1991
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The role of endogenous thyrotropin releasing hormone (TRH) in maintenance of the blood pressure in awake and unrestrained rats with hemorrhagic hypotension
kn-title=無麻酔･無拘束下ラットの出血性低血圧モデルにおける内因性 Thyrotropin releasing hormone (TRH) の血圧維持作用ならびにその作用部位に関する実験的研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A pressor effect of TRH in hemorrhagic hypotensive rats was studied. First, TRH (1mg/kg, 2mg/kg, 5mg/kg), its analogue MK771 (0.2mg/kg) and anti-TRH antibody were given intravenously. The change in the mean arterial blood pressure (MAP) was observed. After administration of TRH, MAP rose dose-dependently, and it also rose after administration of MK771. The anti-TRH antibody significantly suppressed the compensatory and reflective increase of MAP following the hemorrhage. This suggested that the endogenous TRH plays an important role in the maintenance of MAP in the hemorrhagic hypotensive state. Next, the same hypotention models were made using adreno-demedullated rats. TRH or anti-TRH antibody was given intravenously. TRH significantly increased MAP, while the anti-TRH antibody suppressed MAP. This indicates that the pressor effect of TRH is not mediated by the adrenal medulla. The endogenous TRH may play its maintenance role of blood pressure via medulla oblongata.
en-copyright=
kn-copyright=

en-aut-name=MiyazakiMineo
en-aut-sei=Miyazaki
en-aut-mei=Mineo
kn-aut-name=宮崎峰生
kn-aut-sei=宮崎
kn-aut-mei=峰生
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部麻酔・蘇生学教室
en-keyword=出血性低血圧
kn-keyword=出血性低血圧
en-keyword=TRH
kn-keyword=TRH
en-keyword=MK771
kn-keyword=MK771
en-keyword=抗 TRH 抗体
kn-keyword=抗 TRH 抗体
en-keyword=副腎髄質除去ラット
kn-keyword=副腎髄質除去ラット
END

start-ver=1.4
cd-journal=joma
no-vol=103
cd-vols=
no-issue=9-10
article-no=
start-page=1055
end-page=1063
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1991
dt-pub=1991
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Correlation between natural killer (NK) cell activity and graft-versus-host disease (GVHD) after small bowel transplantation of rat - especially for cutaneous GVHD -
kn-title=ラット小腸移植による Graft-Versus-Host Disease (GVHD) と Natural Killer (NK) 細胞活性の相関―特に cutaneous GVHD との関連について―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Using (LEW) parent to (LEW×WKA)F1 combination, heterotopic total small bowel transplantation was performed in rats. We divided this GVHD model into four groups (group 1 ; control, group 2 ; Cyclosporine A (CyA) 5mg/�s 0-2 pod, group 3 ; CyA 5mg/�s 0-6 pod, group 4 ; anti-ASGM1 antibody 50μ1 twice). All rats in group 1 developed cutaneous GVHD on 8 or 9 pod, and developed systemic GVHD and died within 19 pod (Mean Survival Times (MST)＝17.5±1.5). All rats in group 2 developed cutaneous GVHD on 11-14 pod and died in 20-25 pod due to systemic GVHD (MST＝22.7±1.6). However, 3 of the 7 rats in group 3 and none of those in group 4 developed cutaneous GVHD and survival times were elongated (MST≧107.6±106.9, 52.5±41.9). We also evaluated the cytotoxic activity of recipient spleen cells against three strains of rat skin cells (LEW, WKA, (LEW×WKA)F1) and K-562 cell line on 7 pod. In group 1 and 2, cytotoxic activity was augmented, compared with that in normal F1 rat, against all target cells. However, in group 3 and 4, cytotoxic activity was attenuated, compared with that in group 1 and 2, and lower than in normal F1 rat. We considered that this cytotoxic activity was due to MHC non-restricted NK cells, because there were no differences in any kind of target cells. We concluded that the NK cell might play a great role in GVHD, especially for skin lesions.
en-copyright=
kn-copyright=

en-aut-name=FujiokaMasahiro
en-aut-sei=Fujioka
en-aut-mei=Masahiro
kn-aut-name=藤岡正浩
kn-aut-sei=藤岡
kn-aut-mei=正浩
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一外科学教室
en-keyword=小腸移植
kn-keyword=小腸移植
en-keyword=GVHD
kn-keyword=GVHD
en-keyword=NK 細胞
kn-keyword=NK 細胞
en-keyword=AsialoGM 1
kn-keyword=AsialoGM 1
en-keyword=Cyclosporine A
kn-keyword=Cyclosporine A
END

start-ver=1.4
cd-journal=joma
no-vol=104
cd-vols=
no-issue=1-2
article-no=
start-page=165
end-page=176
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=1992
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Two useful indicators for the preoperative prediction of pulmonary and cardiac complications after lung resection
kn-title=肺切除術における術後心肺合併症発生予測のための指数設定及びその臨床的有用性の検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Two indicators (Risk score and Resection Index) for pulmonary and cardiac complications after lung resection were evaluated on 182 patients with bronchogenic carcinoma by quantita-tive technetium 99m macroaggregation albumin (MAA) perfusion scanning preoperatively and who then underwent lung resection. After surgerg, the correlations between preoperative lung function and the development of postoperative pulmonary and cardiac complications (PPCC) were examined in each case. The Risk score consisted of eight parameters (% FVC, FEV 1.0%, % MVV, % MMF, V50/HT, V25/HT, % peak flow, and % DLco), and a value of from 0 to 8 was assigned. In the patients with a Risk score of 0, PPCC occurred in 5 of the 71 cases, while complications were noted in 26 of the 94 patients with a Risk score from 1 to 5 and in 14 of the 17 patients with a score of over 6. The Resection Index was calculated from the predicted postoperative FEV 1.0 from the quantitative 99m Tc MAA perfusion scan and the predicted FEV 1.0, PPCC occurred in 20 of the 27 patients with a Resection Index of below 40%, 25 of the 131 patients with an index of 40% to 65%, and none of the 24 with an index over 65%. Both indicators had a good correlation with the occurrence of PPCC. These two indicators, the Risk score and the Resection Index, were clincally useful for predicting PPCC preoperatively and may help reduce the incidence of PPCC.
en-copyright=
kn-copyright=

en-aut-name=KobashiYuichi
en-aut-sei=Kobashi
en-aut-mei=Yuichi
kn-aut-name=小橋雄一
kn-aut-sei=小橋
kn-aut-mei=雄一
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第二外科学教室
en-keyword=肺癌
kn-keyword=肺癌
en-keyword=肺切除術
kn-keyword=肺切除術
en-keyword=術前肺機能
kn-keyword=術前肺機能
en-keyword=術後心肺合併症発生予測
kn-keyword=術後心肺合併症発生予測
en-keyword=肺血流シンチグラフィー
kn-keyword=肺血流シンチグラフィー
END

start-ver=1.4
cd-journal=joma
no-vol=104
cd-vols=
no-issue=7-8
article-no=
start-page=789
end-page=795
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199208
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The relationships between physique and throwing ability in high school baseball players
kn-title=高校野球選手における形態と投能力の関係
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=There is little information on anthropometric measures (i. e., length, breadth and girth of body's parts) related to throwing ability. To clarify the influence of the physique on the throwing ability, the relationships between physique and throwing distance, as well as ball speed were investigated. The subjects were fourty-nine high school baseball players, and thirty-eight high school volleyball players, football players and canoeists served as a control group. The throwing distance was significantly related to lean body mass (r=.290), chest girth (r=.416), upper arm girth (r=.307), abdominal girth (r=.288), thigh girth (r=.327) and lower leg girth (r=.285) in baseball players group (p<0.05-0.01). A significant relationship between the throwing distance and foot length in control group (r=.329, p<0.05) was demonstrated. Significant relationships between ball speed and standing height in the baseball players group (r=.354, p<0.01) and that  between ball speed and Impedance in the control group (r=-.288, p<0.05) were ovserved. These findings indicate that the throwing distance is influenced by quantity of body muscle in baseball players. There was no relation between physique and throwing ability in unskilled players.
en-copyright=
kn-copyright=

en-aut-name=UchidaHayato
en-aut-sei=Uchida
en-aut-mei=Hayato
kn-aut-name=内田勇人
kn-aut-sei=内田
kn-aut-mei=勇人
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部衛生学教室
en-keyword=野球選手
kn-keyword=野球選手
en-keyword=形態
kn-keyword=形態
en-keyword=遠投距離
kn-keyword=遠投距離
en-keyword=ボールスピード
kn-keyword=ボールスピード
en-keyword=Impedance
kn-keyword=Impedance
END

start-ver=1.4
cd-journal=joma
no-vol=106
cd-vols=
no-issue=5-6
article-no=
start-page=561
end-page=571
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=1994
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Clinical studies on inhalation provocatopn test of Candida antigen in bronchial asthma
kn-title=気管支喘息におけるカンジダ抗原吸入誘発試験の臨床的検討―遅延型気道反応を中心に―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Various allergic mechanisma participate in the reversible bronchospasms of an asthma attack. Candida albicans was suspected as the causative antigen in late-onset and severe intractable asthma. In this study, inhalation provocation test was performed with Candida antigen to evaluate the asthmatic responses of asthmatic patients with positive skin reaction to Candida antigen. More than 20% decrease in park flow after antigen inhalation was considered an asthmatic response and such responses were classified as immediate (IAR), late (LAR) or delayed (DeAR) depending on the time course after antigen inhalation. Provocation tests induced asthmatic responses in 26(42.6%) patients and 11(42.3%) showed DeAR. Eight of the 11 patients with DeARs had late onst asthma and 7 patients had intractable asthma. Furthermore, patients with DeARs showed higher lymphocyte responses to Candida antigen than those with IAR or LAR. These date indicate that EeAR to Canidia antigen plays an important role in the pathogenesis of severe intractable asthma.
en-copyright=
kn-copyright=

en-aut-name=InokiAtsuhiro
en-aut-sei=Inoki
en-aut-mei=Atsuhiro
kn-aut-name=猪木篤弘
kn-aut-sei=猪木
kn-aut-mei=篤弘
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第二内科学教室
en-keyword=難治性喘息
kn-keyword=難治性喘息
en-keyword=カンジダ抗原
kn-keyword=カンジダ抗原
en-keyword=吸入誘発試験
kn-keyword=吸入誘発試験
en-keyword=遅延型気道反応
kn-keyword=遅延型気道反応
en-keyword=リンパ球幼若化反応
kn-keyword=リンパ球幼若化反応
END

start-ver=1.4
cd-journal=joma
no-vol=106
cd-vols=
no-issue=3-4
article-no=
start-page=287
end-page=297
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=1994
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A clinical study of resting energy expenditure in patients with lung cancer : Effect of branched chain amino acid
kn-title=肺癌患者におけるエネルギー代謝の研究―術後における分岐鎖アミノ酸投与の影響について―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The relationship between the nutritional assessment and the energy metabolism in the pre-and postoperative period of lung-resected patients was examined, and the effect of branched chain amino acids on the nutritional state in the early postoperative period was determined. The lung cancer patients had a significantly higher resting energy expenditure than the benign lung disease patients. In the lung cancer patients, progress of stage was accompanied by an increase in the resting energy expenditure and a decrease in the nonprotein respiratory quotient. There was protein calorie maluntrition in ablut 10% of the lung cancer patients, and the decrease of nutrition was accompanied by an increase in the resting energy expenditure. Administration of branched chain amino acids in the early postoperative period did not reduce the increase in the resting energy expenditure, but had a tendency of decreasing the arterial carbon dioxidie tension.
en-copyright=
kn-copyright=

en-aut-name=NaniwaHiroyuki
en-aut-sei=Naniwa
en-aut-mei=Hiroyuki
kn-aut-name=浪花宏幸
kn-aut-sei=浪花
kn-aut-mei=宏幸
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第二外科学教室
en-keyword=間接熱量測定
kn-keyword=間接熱量測定
en-keyword=肺癌
kn-keyword=肺癌
en-keyword=安静時エネルギー消費量
kn-keyword=安静時エネルギー消費量
en-keyword=分岐鎖アミノ酸
kn-keyword=分岐鎖アミノ酸
END

start-ver=1.4
cd-journal=joma
no-vol=105
cd-vols=
no-issue=7-8
article-no=
start-page=665
end-page=671
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1993
dt-pub=199308
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on alveolar lymphocyte proliferation induced by Propionibacterium acnes in sarcoidosis Part 2. Correlation between local lymphocyte response and clinical features in sarcoidosis
kn-title=サルコイドーシス肺リンパ球の Propionibacterium acnes に対する反応性に関する研究 第2編 P. acnes に対する反応性と臨床検査との相関
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Alveolar lymphocyte response by Propionibacterium acnes (P. acnes) in patients with active sarcoidosis was previously reported by our group. The response of alveolar lymphocytes in 34 untreated patients with sarcoidosis was studied in correlation with clinical findings on radiographic, physiologic and bronchoalveolar lavage. There was a significant correlation between lymphocyte blastogenesis and the number of lymphocytes (p<0.05), and CD4(＋) T-cells (p<0.01) obtained by bronchoalveolar lavage. Furthermore, the response was significantly correlated with the activity of Interleukin-2 released by alveolar lymphocytes stimulated by P. acnes (p<0.05). In patients who showed abnormalities on all three clinical examinations, i. e. serum angiotensin converting enzyme activity, number of alveolar lymphocytes and 67Ga scintigraphy of the lung, the response was significantly higher than in the controls (p<0.001) or in patients with none of these abnormalities (p<0.01). These data suggest that the response of alveolar lymphocytes reflects the activity of pulmonary sarcoidosis.
en-copyright=
kn-copyright=

en-aut-name=MaetaTsuyoshi
en-aut-sei=Maeta
en-aut-mei=Tsuyoshi
kn-aut-name=前田剛
kn-aut-sei=前田
kn-aut-mei=剛
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第二内科学教室
en-keyword=Sarcoidosis
kn-keyword=Sarcoidosis
en-keyword=alveolar-lymphocyte
kn-keyword=alveolar-lymphocyte
en-keyword=P. acnes
kn-keyword=P. acnes
en-keyword=Angiotensin-converting enzyme
kn-keyword=Angiotensin-converting enzyme
en-keyword=Gallium-scintigraphy
kn-keyword=Gallium-scintigraphy
END

start-ver=1.4
cd-journal=joma
no-vol=108
cd-vols=
no-issue=3-6
article-no=
start-page=83
end-page=95
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=19960629
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Comparison of postoperative circulatory, respiratory and immunological parameters between one-stage and two-stage surgery of intrathoracic esophageal carcinoma
kn-title=循環，呼吸，免疫動態よりみた胸部食道癌に対する1期的手術と分割手術との比較検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=There are two major surgical procedures for excision of esophageal carcinoma and reconstruction of the esophagus: the one-stage procedure and the two-stage procedure. In the present study, we evaluated the two methods by comparing the cardiovascular, respiratory and immune parameters of 10 patients who underwent one-stage procedure with those of 10 other patients who underwent two-stage procedure. To estimate cardiovascular function, we measured the left ventricular stroke work index (LVSWI)-pulmonary capillary wedge pressure (PCWP). Most of the patients treated by the one-stage procedure showed a significant decrease in LVSWI-PCWP, whereas the index of patients treated by the two-stage procedure did not change much. When we assessed the respiratory system by forced vital capacity (FVC) and peak expiratory flow (PEF), the patients treated by the two-stage procedure recovered much faster and better than those receiving the one-stage procedure. Natural killer (NK) activity in lymphocytes was also measured as a marker of the immuno-reactive system. Although most patients show a drop in NK activity one week after major surgery, NK activity did not demonstrate a significant change in any of the patients who underwent the two-stage procedume. Thus, our systemic comparison of the three different parameters demonstrated better results after the two-stage procedure and we recommend it over the one-stage procedure, especially for aged and high risk patients.
en-copyright=
kn-copyright=

en-aut-name=MuramatsuTomoyoshi
en-aut-sei=Muramatsu
en-aut-mei=Tomoyoshi
kn-aut-name=村松友義
kn-aut-sei=村松
kn-aut-mei=友義
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一外科学教室
en-keyword=intrathoracic esophageal carcinoma
kn-keyword=intrathoracic esophageal carcinoma
en-keyword=one-stage procedure
kn-keyword=one-stage procedure
en-keyword=two-stage procedure
kn-keyword=two-stage procedure
en-keyword=reduction of operative stress
kn-keyword=reduction of operative stress
END

start-ver=1.4
cd-journal=joma
no-vol=116
cd-vols=
no-issue=3
article-no=
start-page=229
end-page=234
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=20050131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=気管支喘息における高分解能CT (high-resolution computed tomography) による評価の有用性―岡山大学医学賞（砂田賞）を受賞して―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=気管支喘息は気道の慢性炎症性疾患であり, 本質的に可逆性障害と考えられるが, 持続的慢性炎症によって生ずる肺実質を含む気道の器質的変化すなわち気道リモデリングが原因で不可逆性気流制限をきたし得ることが知られている. 最近, 高分解能CT (HRCT; high-resolution computed tomography) によって気管支壁肥厚, 気管支拡張, 気腫化, モザイク状低吸収域などの変化の評価が可能であることが報告されている. 気管支喘息患者の気道壁は健常者に比較して肥厚しており, その肥厚の程度は喘息の重症度, 気流制限, 気道反応性に関連していることが明らかになっている. 気道リモデリングを反映するHRCTの異常所見は, 慢性気流制限を有する重症喘息患者においてしばしば認められ, 長期の罹病期間や強い気道炎症と関係するとされている. 我々は, HRCTにおける-950Hounsfield unit (HU) 以下のlow attenuation area (RA(950)) は非喫煙喘息患者においても検出され, 気流制限, 肺気量, 喘息の重症度と相関しているが, 肺拡散能との有意の相関は認めないことを報告してきた. 最近, フラクタル解析によってRA(950)は, 喫煙歴を有する喘息患者では気腫性変化を示すのに対し, 非喫煙喘息患者では非気腫性変化 (過膨張) を示す可能性を示した. さらに, HRCTによって評価された気道壁肥厚およびRA950は, 治療によって改善することが認められており, HRCTは喘息の治療効果判定に有用である可能性が示唆された.
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=光延文裕
kn-aut-sei=光延
kn-aut-mei=文裕
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院医歯学総合研究所　老年医学
en-keyword=気管支喘息
kn-keyword=気管支喘息
en-keyword=高分解能CT
kn-keyword=高分解能CT
en-keyword=low attenuation area
kn-keyword=low attenuation area
en-keyword=気管支壁肥厚
kn-keyword=気管支壁肥厚
en-keyword=気道リモデリング
kn-keyword=気道リモデリング
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=20080630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=血清IP-10値は心筋梗塞患者において増加し、心筋梗塞巣の大きさに負の相関を示した
kn-title=Serum interferon-gamma-inducible protein 10 level was increased in myocardial infarction patients, and negatively correlated with infarct size
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=KotenKazuya
en-aut-sei=Koten
en-aut-mei=Kazuya
kn-aut-name=小天和也
kn-aut-sei=小天
kn-aut-mei=和也
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2007
dt-pub=20071231
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=冠動脈楔入圧にて決定される冠動脈側副血流は冠動脈閉塞中のST上昇と有意に相関する
kn-title=Significant correlation of recruitable coronary collateral blood flow determined by coronary wedge pressure with ST-segment elevation during coronary occlusion
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=KamikawaShigeshi
en-aut-sei=Kamikawa
en-aut-mei=Shigeshi
kn-aut-name=上川滋
kn-aut-sei=上川
kn-aut-mei=滋
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2007
dt-pub=20070930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=コンピュータードラッグデザインに基づく抗腫瘍薬としての新規フラビン類縁体のデザイン，合成および構造活性相関
kn-title=Design,Synthesis, and Structure-Activity Relationships of Novel Flavin Analogs as Antitumor Agents Based on Computer Aided Drug Design
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=HamedIsmail Ali Ismail
en-aut-sei=Hamed
en-aut-mei=Ismail Ali Ismail
kn-aut-name=ハーメドイスマイル アリ イスマイル
kn-aut-sei=ハーメド
kn-aut-mei=イスマイル アリ イスマイル
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2007
dt-pub=20070323
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=渦相関法による大気−海洋間の二酸化炭素輸送量の直接測定に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=KondoFumiyoshi
en-aut-sei=Kondo
en-aut-mei=Fumiyoshi
kn-aut-name=近藤文義
kn-aut-sei=近藤
kn-aut-mei=文義
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=5
cd-vols=
no-issue=
article-no=
start-page=71
end-page=77
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1995
dt-pub=19950131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=リウマチ因子陽性ヒト血清中の免疫グロブリンGクラスリウマチ因子と免疫複合体ならびにCRPとの相関性
kn-title=Correlation between IgG class of rheumatoid factors, immune complexes and C-reactive protein in human sera containing RF.
en-subtitle=
kn-subtitle=
en-abstract=一般に慢性関節リウマチの診断ならびに活動性の一指標として、日常臨床検査では患者血清中のリウマチ因子の測定が実施されている。本論文ではRF検査依頼が有り、高RF値（24.0〜2350.0IU/ml）を示した患者血清74検体について、免疫グロブリンクラス別RF値を測定するとともに自己IgGと補体との免疫複合体（IC）であるC1q-IgG・IC（C1q-IC）、C3d-IgG・IC（C3d-IC）ならびにCRP値を測定し、それらの測定値間の相関性について統計学的検討を行った。C3d-IC値が15.0μg/ml以上の高値を示す患者血清では、CRP値とIgGクラスのRF（IgG-RF）値間については正の相関結果がが得られた。また、C1q-IC値が80.0μg/ml以上の場合にもCRP値とIgG-RF値間およびC3d-IC値とIgG-RF値間では正の相関結果が得られた。しかし、C3d-ICならびにC1q-ICともに高値例の患者血清中のCRP値とC1q-IC値間には有意な相関は観察されなかった。以上の結果より、慢性関節リウマチの活動度を判定する上で、従来から炎症マーカーとしてCRP値が利用されているが、血清中に免疫複合体が高レベルに検出される患者については、炎症の指標としてCRP以外にもC1q-ICやC3d-ICおよびIgG-RF等を加えた総合的な判断が必要であることが示唆される。
kn-abstract=We measured the concentration of three immunoglobulin classes of rheumatoid factors (Ig-RFs), C3d binding IgG immune complex (C3d-IC), C1q binding IgG immune complex (C1q-IC) and C-reactive protein (CRP) in 74 samples of human sera with high levels of RF (24.0~2350.0IU/ml). In sera with high levels of C3d-IC (>15.0μg/ml), there was a positive correlation between the levels of CRP and the IgG-RF, but there was no correlation between the levels of CRP and the immune complexes (C3d-IC and C1q-IC). And then, there was a positive correlation between the levels of CRP and IgG-RF or C3d-IC and IgG-RF when the levels of C1q-IC in patients sera were higher than 80.0μg/ml. However, there was no correlation between the levels of CRP and C1q-IC in these patients sera containing high levels of both C3d-IC and C1q-IC. These results indicated that the determination of C3d-IC, C1q-IC, IgG-RF and CRP in human sera containing RF denote different implications as inflammatory indexes on progression of rheumatoid arthritis and other autoimmune diseases.
en-copyright=
kn-copyright=

en-aut-name=TohgeHiroko
en-aut-sei=Tohge
en-aut-mei=Hiroko
kn-aut-name=唐下博子
kn-aut-sei=唐下
kn-aut-mei=博子
aut-affil-num=1
ORCID=

en-aut-name=IchimuraMitsuko
en-aut-sei=Ichimura
en-aut-mei=Mitsuko
kn-aut-name=一村光子
kn-aut-sei=一村
kn-aut-mei=光子
aut-affil-num=2
ORCID=

en-aut-name=SakiyamaJunko
en-aut-sei=Sakiyama
en-aut-mei=Junko
kn-aut-name=�ｱ山順子
kn-aut-sei=�ｱ山
kn-aut-mei=順子
aut-affil-num=3
ORCID=

en-aut-name=MoriShuji
en-aut-sei=Mori
en-aut-mei=Shuji
kn-aut-name=森秀治
kn-aut-sei=森
kn-aut-mei=秀治
aut-affil-num=4
ORCID=

en-aut-name=NakataYasunari
en-aut-sei=Nakata
en-aut-mei=Yasunari
kn-aut-name=中田安成
kn-aut-sei=中田
kn-aut-mei=安成
aut-affil-num=5
ORCID=

en-aut-name=EndoHiroshi
en-aut-sei=Endo
en-aut-mei=Hiroshi
kn-aut-name=遠藤浩
kn-aut-sei=遠藤
kn-aut-mei=浩
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医療技術短期大学部衛生技術学科

affil-num=2
en-affil=
kn-affil=岡山大学医療技術短期大学部衛生技術学科

affil-num=3
en-affil=
kn-affil=岡山大学医療技術短期大学部衛生技術学科

affil-num=4
en-affil=
kn-affil=岡山大学医療技術短期大学部衛生技術学科

affil-num=5
en-affil=
kn-affil=岡山大学医療技術短期大学部衛生技術学科

affil-num=6
en-affil=
kn-affil=岡山大学医療技術短期大学部衛生技術学科
en-keyword=self-associating IgG rheumatoid factor (自己IgG結合性リウマチ因子)
kn-keyword=self-associating IgG rheumatoid factor (自己IgG結合性リウマチ因子)
en-keyword=C1q binding IgG immune complex (C1q結合IgG免疫複合体)
kn-keyword=C1q binding IgG immune complex (C1q結合IgG免疫複合体)
en-keyword=C3d binding IgG immune complex (C3d結合IgG免疫複合体)
kn-keyword=C3d binding IgG immune complex (C3d結合IgG免疫複合体)
en-keyword=C-reactive protein (C反応性タンパク質(CRP))
kn-keyword=C-reactive protein (C反応性タンパク質(CRP))
END

start-ver=1.4
cd-journal=joma
no-vol=5
cd-vols=
no-issue=
article-no=
start-page=65
end-page=70
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1995
dt-pub=19950131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Antibody to Propionibacterium acnes (P.acnes) in guinea pigs with pulmonary granulomatosis
kn-title=Propionibacterium acnes感作肺肉芽腫モルモットの特異抗体の測定
en-subtitle=
kn-subtitle=
en-abstract=In guinia pig models of P.ances induced pulmonary granulomatosis, anti-P.acnes antibody activity in bronchoalveolar lavage fluid peaked at 1 week after the endotracheally injection and decreased progressively, attaining control animal value by 4 weeks. The change of lymphocyte counts paralleled the change of anti-P.acnes antibody activity levels in bronchoalveolar fluids. Furthermore, the degree of granuloma formation in the lung paralleled the rise of anti-P.acnes antibody activity level. This data suggests that the anti-P.acnes antibody play a central role in the induction of lymphocyte alveolitis in experimental pulmonary granulomatosis.
kn-abstract=P.acnesを皮内前感作した後、P.acnes菌体壁成分をimcomplete Freund's adjuvantと共に気管内に投与して作製した実験的肺肉芽腫症モルモットにおける抗P.acnes抗体について検討した。気管支肺胞洗浄液中抗P.acnes抗体価は気管内投与後1週目ピークを示し2週目までは上昇が認められ、4週目では気管内投与前の値に復した。この経過は肺胞内リンパ球数の変動と軌を一にしており、抗体価とリンパ球数の間には正の強い相関が認められた。血清中の抗P.acnes抗体価は1週目に低下が認められ、2週以後に徐々に回復して4週以後は元に戻った。P.acnesの気管内投与により血清中の抗体は肺へと移行し、リンパ球浸潤による胞隔炎、更には類上皮細胞肉芽腫の形成にP.acnesの関与を示すものであった。
en-copyright=
kn-copyright=

en-aut-name=NakataYasunari
en-aut-sei=Nakata
en-aut-mei=Yasunari
kn-aut-name=中田安成
kn-aut-sei=中田
kn-aut-mei=安成
aut-affil-num=1
ORCID=

en-aut-name=MoriYoshihiro
en-aut-sei=Mori
en-aut-mei=Yoshihiro
kn-aut-name=森由弘
kn-aut-sei=森
kn-aut-mei=由弘
aut-affil-num=2
ORCID=

en-aut-name=EjiriTohgo
en-aut-sei=Ejiri
en-aut-mei=Tohgo
kn-aut-name=江尻東伍
kn-aut-sei=江尻
kn-aut-mei=東伍
aut-affil-num=3
ORCID=

en-aut-name=KataokaMikio
en-aut-sei=Kataoka
en-aut-mei=Mikio
kn-aut-name=片岡幹男
kn-aut-sei=片岡
kn-aut-mei=幹男
aut-affil-num=4
ORCID=

en-aut-name=HiramatsuJun-ichi
en-aut-sei=Hiramatsu
en-aut-mei=Jun-ichi
kn-aut-name=平松順一
kn-aut-sei=平松
kn-aut-mei=順一
aut-affil-num=5
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医療技術短期大学部衛生技術学科

affil-num=2
en-affil=
kn-affil=高松病院

affil-num=3
en-affil=
kn-affil=市立吉備病院

affil-num=4
en-affil=
kn-affil=岡山大学医学部第二内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部第二内科
en-keyword=サルコイドーシス (sarcoidosis)
kn-keyword=サルコイドーシス (sarcoidosis)
en-keyword=プロピオニバクテリウム (propionibacteium acnes)
kn-keyword=プロピオニバクテリウム (propionibacteium acnes)
en-keyword=肺肉芽腫症 (pulmonary granulomatosis)
kn-keyword=肺肉芽腫症 (pulmonary granulomatosis)
en-keyword=動物実験モデル (experimental model)
kn-keyword=動物実験モデル (experimental model)
en-keyword=気管支肺胞洗浄液 (bronchoalveolar lavage)
kn-keyword=気管支肺胞洗浄液 (bronchoalveolar lavage)
END

start-ver=1.4
cd-journal=joma
no-vol=3
cd-vols=
no-issue=
article-no=
start-page=81
end-page=85
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1993
dt-pub=19930131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Relationship between intracellular uptake of adriamycin and membrane potential in ADR resistant Ehrlich ascites tumor cells
kn-title=薬剤耐性細胞におけるアドリアマイシンの細胞内取り込みと細胞膜電位差の相関
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We observed adiamycin (ADR) uptake and cellular transmembrane potential [amount of intracellular fluorescence of 3,3'- (Di-n-hexyl)- 2,2'- oxacarbocyanine iodide (NK-2280)] in ADR-resistant cells established from Ehrlich ascites tumor cells (EATC) and wild type EATC. In ADR-resistant cells, ADR uptake and the cellular transmembrane potential decreased as the degree of resistance increased. 4,4'- diisothiocyanatostilbene- 2,2'- disulfonic acid (DIDS) induced markedly decreases of ADR uptake and the cellular transmembrane potential. A good correlation was observed between ADR uptake and transmembrane potential in cultured cells.
en-copyright=
kn-copyright=

en-aut-name=AsaumiJun-ichi
en-aut-sei=Asaumi
en-aut-mei=Jun-ichi
kn-aut-name=浅海淳一
kn-aut-sei=浅海
kn-aut-mei=淳一
aut-affil-num=1
ORCID=

en-aut-name=KawasakiShoji
en-aut-sei=Kawasaki
en-aut-mei=Shoji
kn-aut-name=川崎祥二
kn-aut-sei=川崎
kn-aut-mei=祥二
aut-affil-num=2
ORCID=

en-aut-name=NishikawaKoji
en-aut-sei=Nishikawa
en-aut-mei=Koji
kn-aut-name=西川光治
kn-aut-sei=西川
kn-aut-mei=光治
aut-affil-num=3
ORCID=

en-aut-name=Shu GaoXian
en-aut-sei=Shu Gao
en-aut-mei=Xian
kn-aut-name=高献書
kn-aut-sei=高献
kn-aut-mei=書
aut-affil-num=4
ORCID=

en-aut-name=KurodaMasahiro
en-aut-sei=Kuroda
en-aut-mei=Masahiro
kn-aut-name=黒田昌宏
kn-aut-sei=黒田
kn-aut-mei=昌宏
aut-affil-num=5
ORCID=

en-aut-name=HirakiYoshio
en-aut-sei=Hiraki
en-aut-mei=Yoshio
kn-aut-name=平木祥夫
kn-aut-sei=平木
kn-aut-mei=祥夫
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線医学教室

affil-num=2
en-affil=
kn-affil=岡山大学医療技術短期大学部診療放射線技術学科

affil-num=3
en-affil=
kn-affil=岡山大学医学部放射線医学教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部放射線医学教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部放射線医学教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部放射線医学教室
en-keyword=Adriamycin
kn-keyword=Adriamycin
en-keyword=Cell Membrane Potential
kn-keyword=Cell Membrane Potential
en-keyword=Flow Cytometry
kn-keyword=Flow Cytometry
en-keyword=ADR-Resistant Cells
kn-keyword=ADR-Resistant Cells
en-keyword=DIDS
kn-keyword=DIDS
END

start-ver=1.4
cd-journal=joma
no-vol=2
cd-vols=
no-issue=
article-no=
start-page=51
end-page=61
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=19920205
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Measurement of Serum Lipid Peroxides used Thiobarbituric Acid Method: Colorimetric and Fluorometric Assays and Effect of Ferrous Ion
kn-title=チオバルビツール酸法による血清過酸化脂質の測定：比色法と蛍光法の比較並びに二価鉄の影響
en-subtitle=
kn-subtitle=
en-abstract=患者血清を試料に脂質過酸化物をTBA法を用い、酢酸酸性下(TBA−AA系）、塩酸酸性下（TBA-HCl系）で加熱反応させ、比色法（TBA[OD]値）と蛍光法（TBA[FR]値）で計測した。併せてFe(++)（Fe-TBA値）、Fe(+++)、EDTAの影響を検討した。両系においてMDAの検量を行った結果、TBA[OD]値は同一数値が得られたが、TBA[FR]値は異なって示された。低TBA値では蛍光法が、高TBA値では比色法が適している結果をみた。しかし、患者血清の定量からはTBA[OD]値、TBA[FR]値で相関は得られたものの、両測定方法に関与する血清内在因子の影響は異なることが示唆された。TBA-AA,TBA-HCl両系に対するFeの影響は異なり、特にTBA-AA系では著しいFe-TBA値が得られ、Fe誘導脂質過酸化反応が加熱発色反応中に誘起されていることが示されたが、EDTA添加でその誘導は抑制された。また、TBA-AA系ではFe(++),Fe(+++)で同様の影響がみられたが、TBA-HCl系では異なった影響がみられた。両系のTBA値、Fe-TBA値の相違の原因としてpH、酢酸の影響が考えられた。患者血清でTBA値とFe-TBA値に相関は得られず、Fe(++)誘導反応に相違がみられ、また、EDTAの抑制作用も血清試料で異なることから、Fe-TBA値で血清の質的な相違が計測できる可能性が示唆された。
kn-abstract=Serum lipid peroxides were measured by a thiobarbituric acid (TBA) method. TBA color reactions carried out under the conditions with acetic acid (TBA-AA) or hydrochloric acid (TBA-HCl) systems, and then TBA value was detected by colorimetric ([OD]) and fluorometric ([FR]) measurements. Effects of ferrous ion, ferric ion and EDTA on the both systems were examined. Equal TBA value dependent upon concentrations of MDA (tetraethoxypropane) were obtained on both systems detected by [OD], but the relative fluorescence of TBA-AA system was higher than that of TBA-HCl system. Fluorometric determination was suitable for low TBA value, and colorimetric one was for high TBA value. Good correlation between TBA[OD] values and TBA[FR] values of serum from patients was estimated, but it was suggested that effects of serum substance were differ on the both systems. Effects of iron on TBA-AA and TBA-HCl systems were different significantly, particularly high Fe-TBA values obtained from TBA-AA system in the presence of ferrous ion. The fact suggests that serum lipid peroxidation is induced by ferrous ion during a heating of TBA color reaction. Same effect of ferric ion in TBA-AA system was observed. The increment of TBA values by ferrous and ferric ions was inhibited by a addition of EDTA. It was considered that the difference effect of iron on the both systems was due to pH and acetic acid concentration. The relationship of TBA values and Fe-TBA values of serum from patients was no correlated, and the various inhibition ratios of EDTA for the TBA value was calculated. It is suggested that Fe-TBA value is possible to detemine the qualitative difference of serum lipid peroxides.
en-copyright=
kn-copyright=

en-aut-name=YamamotoGoki
en-aut-sei=Yamamoto
en-aut-mei=Goki
kn-aut-name=山本剛禧
kn-aut-sei=山本
kn-aut-mei=剛禧
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医療技術短期大学部診療放射線技術学科
en-keyword=Serum Lipid Peroxides
kn-keyword=Serum Lipid Peroxides
en-keyword=Thiobarbituric Acid
kn-keyword=Thiobarbituric Acid
en-keyword=Ferrous Ion
kn-keyword=Ferrous Ion
END

start-ver=1.4
cd-journal=joma
no-vol=7
cd-vols=
no-issue=1
article-no=
start-page=81
end-page=86
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=19960930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Factors involved in the movement of the center of mass in healthy women
kn-title=健康女性の重心動揺変化に及ぼす諸因子
en-subtitle=
kn-subtitle=
en-abstract=During the period of pregnancy, movement of the center of mass due to changes in the posture results from the changes in the body form, and this may cause minor troubles. In this study, we examined body form factors which may be involved in the movement of the center of mass in 37 healthy womem, and obtained the following results. 1) In the examination items of the movement of the center of mass, the moving distance of the center of mass, the envelope area and the area of moving of the center of mass were significantly larger when measured with the eyes open than when measured with the eyes closed, while there were no differences in the means of moving in the x-axis direction and in the y-axis direction whether the eyes were open or closed. 2) The moving examinations of the center of mass in the Romberg's posture with open or closed eyes suggested positive correlations with the sitting height and the length of the inferir limb and a negative correlation with the obesity level.
kn-abstract=妊娠中の体形変化は姿勢変化をもたらし、このためにおこる重心移動がマイナートラブルを起こす原因となることが考えられる。そこで、健康女性37人を対象に、重心動揺を起こす因子と考えられる体型要因に着目した基礎的研究を行い、以下の結果を得た。1）重心動揺測定項目の中で、重心動揺距離、包絡面積、重心動揺面積の項目は開眼時より閉眼時が有意に数値が大きく、X軸方向動揺平均、Y軸方向動揺平均の項目は、開眼時と閉眼時とで差がなかった。2）ロンベルグ姿勢での開眼及び閉眼重心動揺検査では、座高、下肢長に正の相関が、肥満度に負の相関があるこが示唆された。
en-copyright=
kn-copyright=

en-aut-name=ShiraiKiyoko
en-aut-sei=Shirai
en-aut-mei=Kiyoko
kn-aut-name=白井喜代子
kn-aut-sei=白井
kn-aut-mei=喜代子
aut-affil-num=1
ORCID=

en-aut-name=GodaNoriko
en-aut-sei=Goda
en-aut-mei=Noriko
kn-aut-name=合田典子
kn-aut-sei=合田
kn-aut-mei=典子
aut-affil-num=2
ORCID=

en-aut-name=OkazakiYuka
en-aut-sei=Okazaki
en-aut-mei=Yuka
kn-aut-name=岡�ｱ愉加
kn-aut-sei=岡�ｱ
kn-aut-mei=愉加
aut-affil-num=3
ORCID=

en-aut-name=JinFumio
en-aut-sei=Jin
en-aut-mei=Fumio
kn-aut-name=神文雄
kn-aut-sei=神
kn-aut-mei=文雄
aut-affil-num=4
ORCID=

en-aut-name=OhtaTakeo
en-aut-sei=Ohta
en-aut-mei=Takeo
kn-aut-name=太田武夫
kn-aut-sei=太田
kn-aut-mei=武夫
aut-affil-num=5
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医療技術短期大学部専攻科助産学特別専攻

affil-num=2
en-affil=
kn-affil=岡山大学医療技術短期大学部専攻科助産学特別専攻

affil-num=3
en-affil=
kn-affil=岡山大学医療技術短期大学部専攻科助産学特別専攻

affil-num=4
en-affil=
kn-affil=岡山大学医療技術短期大学部一般教育

affil-num=5
en-affil=
kn-affil=岡山大学医療技術短期大学部看護学科
en-keyword=重心動揺 (Sway of the center of gravity)
kn-keyword=重心動揺 (Sway of the center of gravity)
en-keyword=直立姿勢 (upright standing position)
kn-keyword=直立姿勢 (upright standing position)
en-keyword=健康女性 (healthy females)
kn-keyword=健康女性 (healthy females)
en-keyword=体型 (body build)
kn-keyword=体型 (body build)
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2007
dt-pub=20070323
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=重症患者ではヘム代謝が増加する：呼気一酸化炭素、動脈血一酸化炭素ヘモグロビンと血清ビリルビンIXαの相関
kn-title=Increased heme catabolism in critically ill patients: correlation among exhaled carbon monoxide, arterial carboxyhemoglobin, and serum bilirubin IXα concentrations
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=It has been reported that exhaled carbon monoxide (CO) concentrations and arterial carboxyhemoglobin (CO-Hb) concentration in blood may be increased in critically ill patients. However, there was no study that examined correlation among amount of CO in exhaled air, CO-Hb concentrations in erythrocytes, and bilirubin IXalpha (BR) in serum, i.e., the three major indexes of heme catabolism, within the same subject. Here, we examined CO concentrations in exhaled air, CO-Hb concentrations in arterial blood, and BR levels in serum in 29 critically ill patients. Measurements of exhaled CO, arterial CO-Hb, and serum total BR have been done in the intensive care unit. As control, exhaled CO concentration was also measured in eight healthy volunteers. A median exhaled CO concentration was significantly higher in critically ill patients compared with control. There was significant correlation between CO and CO-Hb and CO and total BR level. We also found CO concentrations correlated with indirect BR but not direct BR. Multivariate linear regression analysis for amount of exhaled CO concentrations also showed significant correlation with CO-Hb and total BR, despite the fact that respiratory variables of study subjects were markedly heterogeneous. We found no correlation among exhaled CO, patients' severity, and degree of inflammation, but we found a strong trend of a higher exhaled CO concentration in survivors than in nonsurvivors. These findings suggest there is an increased heme breakdown in critically ill patients and that exhaled CO concentration, arterial CO-Hb, and serum total BR concentrations may be useful markers in critically ill conditions.
en-copyright=
kn-copyright=

en-aut-name=MorimatsuHiroshi
en-aut-sei=Morimatsu
en-aut-mei=Hiroshi
kn-aut-name=森松博史
kn-aut-sei=森松
kn-aut-mei=博史
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
en-keyword=heme oxygenase
kn-keyword=heme oxygenase
en-keyword=oxidative stress
kn-keyword=oxidative stress
END

start-ver=1.4
cd-journal=joma
no-vol=6
cd-vols=
no-issue=
article-no=
start-page=35
end-page=40
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=19960229
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A subjective well-being of the aged - psychological characteristics of elderly people of 90 or older -
kn-title=高齢者の主観的幸福感に関する研究 ―90歳以上の特徴―
en-subtitle=
kn-subtitle=
en-abstract=The population of the aged is currently increasing with advanced medical science and technology. The aged have become to keep their lives long. In this paper, We especially focused on their psychological characteristics of elderly people of 90 and older to offer high quality of nursing care for them. We interviewed 50 patients of 80 years and older about a subjective well-being, using a questionaire based on Philadelphia Geriatric Center Morale Scale. And also we asked 50 nurses, who took care of them exclusively, a questinaire about their images of the aged. We report as follows : 1. The nurses estimated that their images of the second group (range : 90 years old ~) were better than the first group (range : 80~89 years old). 2. In subjective well-being which Philadelphia Geriatric Center Morale Scale showed, above-mentioned both groups were similar in total scores. However, each item was marked differently by them. 3. In both groups, their subjective well-being correlated with good images for them.
kn-abstract=高齢化社会の到来に伴い一言で老人といっても幅広い年代が対象となり、一律に老人では説明できない。実際看護をしていると90歳をすぎた老人はその年代迄にはない、穏やかさ、焦りのなさ、人生を達観しているような感じを受けることが多い。そこで90歳以上の老人にみられるイメージや心理面の特徴を明らかにし看護実践の一助としたいと考えた。方法は80歳以上の入院患者50名に身体、生活、家族面からみた現状、他者から見たイメージ、主観的幸福感を調査した。その結果、90歳以上は80歳代にくらべ看護者に肯定的イメージに受け取られる傾向にあった。主観的幸福感を示すモラール得点の総合点では差はなかったが得点する内容に差が見られ、80歳は積極的な生き方で得点しているものが多く90歳代は現状に満足している点で得点している者が多かった。看護者からみたイメージと本人の主観的幸福感は両年代とも肯定的イメージで相関した。
en-copyright=
kn-copyright=

en-aut-name=IkedaToshiko
en-aut-sei=Ikeda
en-aut-mei=Toshiko
kn-aut-name=池田敏子
kn-aut-sei=池田
kn-aut-mei=敏子
aut-affil-num=1
ORCID=

en-aut-name=KondoMasuko
en-aut-sei=Kondo
en-aut-mei=Masuko
kn-aut-name=近藤益子
kn-aut-sei=近藤
kn-aut-mei=益子
aut-affil-num=2
ORCID=

en-aut-name=SakuraiKeiko
en-aut-sei=Sakurai
en-aut-mei=Keiko
kn-aut-name=桜井桂子
kn-aut-sei=桜井
kn-aut-mei=桂子
aut-affil-num=3
ORCID=

en-aut-name=FutoyuYoshiko
en-aut-sei=Futoyu
en-aut-mei=Yoshiko
kn-aut-name=太湯好子
kn-aut-sei=太湯
kn-aut-mei=好子
aut-affil-num=4
ORCID=

en-aut-name=AshikiAkemi
en-aut-sei=Ashiki
en-aut-mei=Akemi
kn-aut-name=阿式明美
kn-aut-sei=阿式
kn-aut-mei=明美
aut-affil-num=5
ORCID=

en-aut-name=SeitaReiko
en-aut-sei=Seita
en-aut-mei=Reiko
kn-aut-name=清田玲子
kn-aut-sei=清田
kn-aut-mei=玲子
aut-affil-num=6
ORCID=

en-aut-name=TanimotoNobuko
en-aut-sei=Tanimoto
en-aut-mei=Nobuko
kn-aut-name=谷本伸子
kn-aut-sei=谷本
kn-aut-mei=伸子
aut-affil-num=7
ORCID=

en-aut-name=AndoSakiko
en-aut-sei=Ando
en-aut-mei=Sakiko
kn-aut-name=安藤佐記子
kn-aut-sei=安藤
kn-aut-mei=佐記子
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医療技術短期大学部看護学科

affil-num=2
en-affil=
kn-affil=岡山大学医療技術短期大学部看護学科

affil-num=3
en-affil=
kn-affil=岡山県看護教育研究会(老人看護分科会)

affil-num=4
en-affil=
kn-affil=岡山県看護教育研究会(老人看護分科会)

affil-num=5
en-affil=
kn-affil=岡山県看護教育研究会(老人看護分科会)

affil-num=6
en-affil=
kn-affil=岡山県看護教育研究会(老人看護分科会)

affil-num=7
en-affil=
kn-affil=岡山県看護教育研究会(老人看護分科会)

affil-num=8
en-affil=
kn-affil=岡山県看護教育研究会(老人看護分科会)
en-keyword=高齢者 (the aged people)
kn-keyword=高齢者 (the aged people)
en-keyword=イメージ (image of the aged)
kn-keyword=イメージ (image of the aged)
en-keyword=幸福感 (well-being)
kn-keyword=幸福感 (well-being)
END

start-ver=1.4
cd-journal=joma
no-vol=6
cd-vols=
no-issue=
article-no=
start-page=23
end-page=28
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=19960229
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Percentage body fat and results of a periodic health examination
kn-title=体脂肪率と定期健康診断成績
en-subtitle=
kn-subtitle=
en-abstract=Data from periodic health examinations such as ALP, UA, RBC, Hb, SGOT, SGPT, Tch(total choresterol), TG(triglyceride), blood pressure, body length, body weight and also percentage body fat(% Fat) as measured by bioelectrical impedance mehtod were obtained from 235 male and 137 female workers at a brewery factory in Okayama Prefecture and results were analyzed. The correlation coefficients for % Fat and Body Mass Index values(BMI) are found to be 0.678 for males and 0.803 for females. Examinees were then devided into normal and obesity groups respectively, and the frequency of values over normal ranges (classified by obesity indicators such as % Fat, BMI and obesity rate calculated from standard weight) were statistically compared. Results showed that % Fat and BMI were more sensitive than obesity rate and that the obesity group had statistically high frequencies of abnormality in some of the data as in the case of SGPT, γGTP and TG compared to the control group. Furthermore this tendency was found to be more significant among male workers than female ones.
kn-abstract=肥満や栄養過剰は多くの慢性疾患、とりわけ成人病と関連が強いことが従来から指摘されている。肥満の判定には体脂肪率を測定することが重要であるが、その方法の一つとして、集団検診に使用しやすい生体電気インピーダンス法（bioelectrical impedance analysis）がある。今回、1ビール製造工場の定期健康診断において、対象者男235人および女137人の体脂肪率をこの方法により測定した。まずこの体脂肪率とBMIおよび肥満度との相関関係を求め、男性より女性において相関が高いことを認めた。ついで肥満群と正常群に分けて、血圧および血液検査の異常率の出現頻度を統計的に比較したところ、肥満群では男女共に総コレステロールで、また男性では尿酸、γGTP、SGPTの各値で、異常者が高率であることを認めた。またSGPTは30才台から、γGTP及びTchは40才台からその傾向が見られた。しかし、肥満指数とこれらの検査値との相関係数は高くはなかった。
en-copyright=
kn-copyright=

en-aut-name=OhtaTakeo
en-aut-sei=Ohta
en-aut-mei=Takeo
kn-aut-name=太田武夫
kn-aut-sei=太田
kn-aut-mei=武夫
aut-affil-num=1
ORCID=

en-aut-name=GotoAkio
en-aut-sei=Goto
en-aut-mei=Akio
kn-aut-name=後藤彰夫
kn-aut-sei=後藤
kn-aut-mei=彰夫
aut-affil-num=2
ORCID=

en-aut-name=MasakiHisako
en-aut-sei=Masaki
en-aut-mei=Hisako
kn-aut-name=正木久子
kn-aut-sei=正木
kn-aut-mei=久子
aut-affil-num=3
ORCID=

en-aut-name=TakamiYoko
en-aut-sei=Takami
en-aut-mei=Yoko
kn-aut-name=高見陽子
kn-aut-sei=高見
kn-aut-mei=陽子
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医療技術短期大学部看護学科

affil-num=2
en-affil=
kn-affil=倉敷成人病健診センター

affil-num=3
en-affil=
kn-affil=倉敷成人病健診センター

affil-num=4
en-affil=
kn-affil=キリンビール岡山工場健康管理室
en-keyword=体脂肪率 (percentage body fat)
kn-keyword=体脂肪率 (percentage body fat)
en-keyword=インピーダンス (bioelectorical impedance)
kn-keyword=インピーダンス (bioelectorical impedance)
en-keyword=BIA
kn-keyword=BIA
en-keyword=健康診断 (periodic health examination)
kn-keyword=健康診断 (periodic health examination)
en-keyword=BMI
kn-keyword=BMI
END

start-ver=1.4
cd-journal=joma
no-vol=10
cd-vols=
no-issue=2
article-no=
start-page=69
end-page=76
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2000
dt-pub=20000324
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An experimental study on the relation of T2-signal high intensity in MRI to histopathological changes in the kainic acid model of temporal lobe epilepsy in rats.
kn-title=ラットにおけるカイニン酸けいれん発作重積後のMRI所見と病理所見の関係
en-subtitle=
kn-subtitle=
en-abstract=The relation of T2-signal high intensity areas observed in temporal lobe epilepsy to histopathological changes in limbic structures was examined in the rat kainic acid (KA) model of epilepsy. Male 8-week-old Sprague-Dawley rats were injected with 10mg/kg(i.p.) of KA or saline (control). Repetitive generalized convulsions (stage 3, or stage 4,5 seizures of amygdala kindled seizures) lasted for 3 to 4 hrs. were induced by KA injection in all rats. MRI was recorded on the day before the KA injection and 1, 2, 4, 8 weeks after the injection by fluid-attenuated inversion recovery method under deep pentobarbital anesthesia. Following the last MRI recording, rats were perfused with 4% paraformaldehyde (PFA) from left cardiac ventricle, post-fixed overnight in 4% PFA and brains were embedded in parafin. Coronal brain sections (6μm) were stained with cresyl violet, or mouse anti-GFAP antibody followed by biotinylated goat anti-mouse IgG and avidin-biotin-peroxidase (vectastain ABC kit). Irregularshaped moderate to severe high T2-signal areas were observed in bilateral piriform and entorhinal cortex in MRI. These high T2-signal areas were ovserved from 1 week after the KA injection to 8 weeks after the injection, and were more prominent in rats elicited stage 4 or 5 seizures than in rats elicited stage 3 seizures. Loss of pyramidal neurons and increased GFAP immunoreactivity were observed in piriform cortex, entorhinal cortex, CA1, subiculum, and hilus of dentate gyrus. The increase of GFAP immunoreactivity, but not the intensity of neuronal loss, in piriform and entorhinal cortex was almost correponded to the size and intensity of T2-signal. However, the increase of GFAP immunoreactivity in hippocampus was not detected as the increase of T2-signal in MRI. These findings indicate that astroglial reactions in piriform and entorhinal cortex are more sensitive to T2-weighted MRI than those in hippocampus.
kn-abstract=側頭葉てんかんでは，てんかん焦点に一致してMRI T2高信号領域が見られ，FLAIR法でこれがより明瞭になるが，このMRI所見と病理組織学的変化との関係は必ずしもはっきりしていない。そこで，Sprague−Dawleyラットにカイニン酸（KA）でけいれん発作重積状態を起こし，経時的にMRIを記録するとともに，ニッスル染色，GFAP免疫染色での病理組織学的変化を調べて両者の関係について検討した。KA群では，MRIで1〜8週間後のいずれにおいてもpiriform cortexからentorhinal cortexにかけて不整形のT2高信号領域がみられたが，stage3のけいれん発作しか出現しなかったラットではstage4，5が出現したラットに比べて程度が弱かった。組織学的には，CA1，subiculum，piriform cortex，entorhinal cortexで神経細胞の消失，濃染細胞の増加と萎縮，GFAP免疫反応の増強が見られたが，piriform cortex，entorhinal cortexでの神経細胞消失の程度はT2信
号の程度と相関せず，GFAP免疫反応が増強した領域に一致して高信号がみられた。しかし，海馬のGFAP免疫反応増強はMRI所見に反映されず，これはMRIの解像度の限界にもよると考えられた。
en-copyright=
kn-copyright=

en-aut-name=SakiyamaJunko
en-aut-sei=Sakiyama
en-aut-mei=Junko
kn-aut-name=�ｱ山順子
kn-aut-sei=�ｱ山
kn-aut-mei=順子
aut-affil-num=1
ORCID=

en-aut-name=OkamotoMotoi
en-aut-sei=Okamoto
en-aut-mei=Motoi
kn-aut-name=岡本基
kn-aut-sei=岡本
kn-aut-mei=基
aut-affil-num=2
ORCID=

en-aut-name=KitamuraYoshihiro
en-aut-sei=Kitamura
en-aut-mei=Yoshihiro
kn-aut-name=北村吉宏
kn-aut-sei=北村
kn-aut-mei=吉宏
aut-affil-num=3
ORCID=

en-aut-name=YamadaNorihito
en-aut-sei=Yamada
en-aut-mei=Norihito
kn-aut-name=山田了士
kn-aut-sei=山田
kn-aut-mei=了士
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部保健学科検査技術科学専攻

affil-num=2
en-affil=
kn-affil=岡山大学医学部保健学科検査技術科学専攻

affil-num=3
en-affil=
kn-affil=岡山療護センター

affil-num=4
en-affil=
kn-affil=岡山大学医学部医学科神経精神医学講座
en-keyword=カイニン酸 (kainic acid)
kn-keyword=カイニン酸 (kainic acid)
en-keyword=MRI
kn-keyword=MRI
en-keyword=FLAIR法 (FLAIR)
kn-keyword=FLAIR法 (FLAIR)
en-keyword=神経細胞死 (neuronal death)
kn-keyword=神経細胞死 (neuronal death)
en-keyword=GFAP
kn-keyword=GFAP
END

start-ver=1.4
cd-journal=joma
no-vol=11
cd-vols=
no-issue=1
article-no=
start-page=17
end-page=24
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2000
dt-pub=20001116
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Study for self-efficacy of intensive care unit nursing
kn-title=ICU看護ケアの自己効力に関する研究
en-subtitle=
kn-subtitle=
en-abstract=The purposes of this study were; (1) to examine the self-efficacy of ICU nursing, and (2) to clear the factors related to the self-efficacy of ICU nursing, (3) to investigate between the self-efficacy of ICU nursing and the self-efficacy of leadership for 15 nurses who had experience more than 3 years in the ICU section. Subjects were 45 ICU working nurses whose average age was 27.8±5.0. Using originally designed scales of self-efficacy of ICU nursing and the self-efficacy of leadership, we found following results; (1) the self-efficacy of ICU nursing was significantly related to age (r(s)=0.35, p<0.05), duration of experience as a nurse (r(s)=0.35, p<0.05) and that of ICU (r(s)=0.56, p<0.01). (2) there were no significant relation between the self-efficacy of ICU
nursing and desire to be ICU nurse, job satisfaction and belief in positive effect of her nursing care for patient's recovery. (3) the self-efficacy of ICU nursing didn't have significant relationship to the self-efficacy of leadership.
kn-abstract=ICU看護婦の看護ケアの自信（以下ICU看護ケアの自己効力とする）の程度を知り，ICU看護ケアの自己効力に影響する要因を明らかにすると同時に，ICU経験3年以上の15名の看護婦についてはICU看護ケアの自己効力とリーダーとしての自信（以後リーダーシップの自己効力とする）との関係を明らかにすることを目的する。ICU看護ケアの自己効力とリーダーシップの自己効力について尺度を作成し，ICU勤務の看護婦48名を対象として調査を行った。有効回答数は45で，平均年齢は27.8±5.0歳であった。その結果，以下の3点が明らかとなった。1．年齢，看護婦経験年数，ICUでの経験年数が増すごとにICU看護ケアの自己効力も上昇していた（年齢：r(s)＝0.35，pく0.05，看護婦経験年数：r(s)＝0.35，pく0.05，ICUでの経験年数：r(s)＝0.56，P＜0.01）。2．配属の希望の有無，職場に満足しているか否か，看護ケアが患者の回復に影響すると考えているか否かについては，ICU看護ケアの自己効力への影響を認めなかった。3．リーダー役割をとっている看護婦のICU看護ケアの自己効力とリーダーシップの自己効力の間には，有意な相関はみられなかった。
en-copyright=
kn-copyright=

en-aut-name=KajikiyoTomomi
en-aut-sei=Kajikiyo
en-aut-mei=Tomomi
kn-aut-name=梶清友美
kn-aut-sei=梶清
kn-aut-mei=友美
aut-affil-num=1
ORCID=

en-aut-name=KanetadaTamayo
en-aut-sei=Kanetada
en-aut-mei=Tamayo
kn-aut-name=金只共世
kn-aut-sei=金只
kn-aut-mei=共世
aut-affil-num=2
ORCID=

en-aut-name=NakanishiMisako
en-aut-sei=Nakanishi
en-aut-mei=Misako
kn-aut-name=中西美佐子
kn-aut-sei=中西
kn-aut-mei=美佐子
aut-affil-num=3
ORCID=

en-aut-name=KubotaChiyoka
en-aut-sei=Kubota
en-aut-mei=Chiyoka
kn-aut-name=窪田千代香
kn-aut-sei=窪田
kn-aut-mei=千代香
aut-affil-num=4
ORCID=

en-aut-name=SumiyoshiKazuko
en-aut-sei=Sumiyoshi
en-aut-mei=Kazuko
kn-aut-name=住吉和子
kn-aut-sei=住吉
kn-aut-mei=和子
aut-affil-num=5
ORCID=

en-aut-name=KawataChieko
en-aut-sei=Kawata
en-aut-mei=Chieko
kn-aut-name=川田智恵子
kn-aut-sei=川田
kn-aut-mei=智恵子
aut-affil-num=6
ORCID=

en-aut-name=YamadaKazuaki
en-aut-sei=Yamada
en-aut-mei=Kazuaki
kn-aut-name=山田一朗
kn-aut-sei=山田
kn-aut-mei=一朗
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院集中治療部

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院集中治療部

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院集中治療部

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院集中治療部

affil-num=5
en-affil=
kn-affil=岡山大学医学部保健学科看護学専攻

affil-num=6
en-affil=
kn-affil=岡山大学医学部保健学科看護学専攻

affil-num=7
en-affil=
kn-affil=岡山大学医学部保健学科看護学専攻
en-keyword=自己効力 (Self-efficacy)
kn-keyword=自己効力 (Self-efficacy)
en-keyword=ICU看護ケア (ICU Nursing)
kn-keyword=ICU看護ケア (ICU Nursing)
en-keyword=リーダーシップ (Leadership)
kn-keyword=リーダーシップ (Leadership)
END

start-ver=1.4
cd-journal=joma
no-vol=61
cd-vols=
no-issue=
article-no=
start-page=89
end-page=97
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1990
dt-pub=199009
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Clinical significance of eosinophilic leucocytes in onset mechanisms of bronchial asthma
kn-title=気管支喘息の発症病態における好酸球の臨床的意義
en-subtitle=
kn-subtitle=
en-abstract=Participation of eosinophil leucocytes in onset mechanisms of bronchial asthma was discussed in following sections ; 1. changes in number of eosinophils in the peripheral
blood, 2. emergence of eosinophils in local allergic reaction sites, 3. eosinophils and allergic reactions, 4. different functions of eosinophils III allergic reactions, 5. eosinophils and clinical types of bronchial asthma. The results showed that eosinophilia in the peripheral blood was generally observed in patients with bronchial asthma.
In these cases, eosinophils migrated into local allergic reaction sites. A reversed correlation was present between number of eosinophils and macrophages, and number of
eosinophils correlated to a certain extent with number of lymphocytes in the small airways and alveolar region.
Function of eosinophils was shown to be different between IgE-and non-IgE-mediated reactions, by measurement of
arylsulfatase activity III BALF. Marked eosinophilia in BALF was observed in any clinical types of atopic asthma, although eosinophils were increased only in bronchoconstriction + hypersecretion type (type
II) of non-atopic asthma.
kn-abstract=末梢血好酸球が気管支喘息の発症病態にどのように関与しているかについて，1．末梢血好酸球の変動，2．好酸球の局所出現，3，好酸球とアレルギー反応，4．アレルギー反応と好酸球の機能，5．好酸球と喘息の臨床病態の各項目で検討した。その結果，気管支喘息では，全般的に末梢血好酸球増多がみられ，同時にアレルギー反応局所への遊走が観察されること，末梢気
道では，ある程度肺胞マクロファージの出現と逆相関にあること，リンパ球との関連もある程度認められることなどが示された。そして，局所出現した好酸球は，IgE抗体の関与の程度により，その機能が異なる可能性が示唆された。また臨床病型別の検討では，アトピー型ではいずれの臨床山型においても好酸球の出現率は明かな増加傾向を示したが，非アトピー型では，Ib．気管支攣縮＋過分二型においてのみ好酸球増多が著明であった。
en-copyright=
kn-copyright=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=1
ORCID=

en-aut-name=SudoMichiyasu
en-aut-sei=Sudo
en-aut-mei=Michiyasu
kn-aut-name=周藤眞康
kn-aut-sei=周藤
kn-aut-mei=眞康
aut-affil-num=2
ORCID=

en-aut-name=KitaniHikaru
en-aut-sei=Kitani
en-aut-mei=Hikaru
kn-aut-name=貴谷光
kn-aut-sei=貴谷
kn-aut-mei=光
aut-affil-num=3
ORCID=

en-aut-name=KawauchiKazuhisa
en-aut-sei=Kawauchi
en-aut-mei=Kazuhisa
kn-aut-name=河内和久
kn-aut-sei=河内
kn-aut-mei=和久
aut-affil-num=4
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=5
ORCID=

en-aut-name=TadaShinya
en-aut-sei=Tada
en-aut-mei=Shinya
kn-aut-name=多田慎也
kn-aut-sei=多田
kn-aut-mei=慎也
aut-affil-num=6
ORCID=

en-aut-name=TakahashiKiyoshi
en-aut-sei=Takahashi
en-aut-mei=Kiyoshi
kn-aut-name=高橋清
kn-aut-sei=高橋
kn-aut-mei=清
aut-affil-num=7
ORCID=

en-aut-name=KimuraIkuro
en-aut-sei=Kimura
en-aut-mei=Ikuro
kn-aut-name=木村郁郎
kn-aut-sei=木村
kn-aut-mei=郁郎
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=7
en-affil=
kn-affil=岡山大学医学部附属病院第二内科

affil-num=8
en-affil=
kn-affil=岡山大学医学部附属病院第二内科
en-keyword=好酸球 (Eosinophils)
kn-keyword=好酸球 (Eosinophils)
en-keyword=肺生検 (Lung biopsy)
kn-keyword=肺生検 (Lung biopsy)
en-keyword=気管支肺胞洗浄 (Bronchoalveolar lavage)
kn-keyword=気管支肺胞洗浄 (Bronchoalveolar lavage)
en-keyword=臨床病型 (Clinical type)
kn-keyword=臨床病型 (Clinical type)
en-keyword=気管支喘息 (Bronchial asthma)
kn-keyword=気管支喘息 (Bronchial asthma)
END

start-ver=1.4
cd-journal=joma
no-vol=61
cd-vols=
no-issue=
article-no=
start-page=16
end-page=22
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1990
dt-pub=199009
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=気管支喘息患者末梢血好塩基球の抗ヒトIgEおよびカルシウムイオノフォァA23187に対する反応性について
kn-title=Basophil reactivity to anti-IgE and calcium ionophore A23187 in patients with bronchial asthma
en-subtitle=
kn-subtitle=
en-abstract=気管支喘息27例および健康人7名を対象に，抗ヒトIgEおよびカルシウムイオノフォァA23187（CaI)刺激時の末梢血好塩基球からのヒスタミン遊離について検討を加えた。(1)抗ヒトIgEおよびCaI刺激時の好塩基球からのヒスタミン遊離は，非アトピー型喘息に比べ，アトピー型喘息において有意に高い値を示した。(2)これらの刺激物質によるヒスタミン遊離は，非使用例に比べ，ステロイド依存性喘息において低い傾向がみられた。また，年齢では39才以下，発症年齢では39才以下でヒズタミン遊離がより高い傾向がみられた。(3)血清IgE値の高い症例の好塩基球は，低い症例に比べより多くのヒスタミンを遊離する傾向がみられた。(4)全般的には，抗ヒトIgE刺激によるヒスタミン遊離とCaI刺激時の遊離との間にはある程度の相関がみられた。以上の結果より，好塩基球の反応性はいろいろの条件下でかなり異なることが示唆された。
kn-abstract=The release of histamine from basophils induced by anti-lgE and calcium ionophore A 23187 ( Cal) was examined in 27 patients with bronchial asthma and 7 healthy subjects, using a whole blood method. (1)The release of histamine induced by anti-IgE and CaI was significantly higher in atopic asthmatics than in non-atopic cases. (2) The histamine release with anti-lgE and CaI was significantly lower in cases with long-term steroid therapy compared to the release in cases without steroid therapy. (3) The release with anti-lgE and CaI was increased in cases
with age of 0-39 years and in cases wpth age at onset of 0-39 years. (4) Anti-IgE induced release correlated to a certain extent with the release induced by CaI. These results show that basophil reactivity as expressed by histamine release changes under different conditions.
en-copyright=
kn-copyright=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=1
ORCID=

en-aut-name=SudoMichiyasu
en-aut-sei=Sudo
en-aut-mei=Michiyasu
kn-aut-name=周藤眞康
kn-aut-sei=周藤
kn-aut-mei=眞康
aut-affil-num=2
ORCID=

en-aut-name=KitaniHikaru
en-aut-sei=Kitani
en-aut-mei=Hikaru
kn-aut-name=貴谷光
kn-aut-sei=貴谷
kn-aut-mei=光
aut-affil-num=3
ORCID=

en-aut-name=KawauchiKazuhisa
en-aut-sei=Kawauchi
en-aut-mei=Kazuhisa
kn-aut-name=河内和久
kn-aut-sei=河内
kn-aut-mei=和久
aut-affil-num=4
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=御舩尚志
kn-aut-sei=御舩
kn-aut-mei=尚志
aut-affil-num=5
ORCID=

en-aut-name=OkudaHiroyuki
en-aut-sei=Okuda
en-aut-mei=Hiroyuki
kn-aut-name=奥田博之
kn-aut-sei=奥田
kn-aut-mei=博之
aut-affil-num=6
ORCID=

en-aut-name=KomagoeHaruki
en-aut-sei=Komagoe
en-aut-mei=Haruki
kn-aut-name=駒越春樹
kn-aut-sei=駒越
kn-aut-mei=春樹
aut-affil-num=7
ORCID=

en-aut-name=TadaShinya
en-aut-sei=Tada
en-aut-mei=Shinya
kn-aut-name=多田慎也
kn-aut-sei=多田
kn-aut-mei=慎也
aut-affil-num=8
ORCID=

en-aut-name=TakahashiKiyoshi
en-aut-sei=Takahashi
en-aut-mei=Kiyoshi
kn-aut-name=高橋清
kn-aut-sei=高橋
kn-aut-mei=清
aut-affil-num=9
ORCID=

en-aut-name=KimuraIkuro
en-aut-sei=Kimura
en-aut-mei=Ikuro
kn-aut-name=木村郁郎
kn-aut-sei=木村
kn-aut-mei=郁郎
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科

affil-num=6
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院産科婦人科

affil-num=7
en-affil=
kn-affil=岡山大学医学部附属病院第二内科

affil-num=8
en-affil=
kn-affil=岡山大学医学部附属病院第二内科

affil-num=9
en-affil=
kn-affil=岡山大学医学部附属病院第二内科

affil-num=10
en-affil=
kn-affil=岡山大学医学部附属病院第二内科
en-keyword=Histamine release (ヒスタミン遊離)
kn-keyword=Histamine release (ヒスタミン遊離)
en-keyword=Basophils (好塩基球)
kn-keyword=Basophils (好塩基球)
en-keyword=Anti-lgE (抗ヒトIgE)
kn-keyword=Anti-lgE (抗ヒトIgE)
en-keyword=Calcium ionophore A 23187 (カルシウムイオノフォァA23187)
kn-keyword=Calcium ionophore A 23187 (カルシウムイオノフォァA23187)
en-keyword=Bronchial asthma (気管支喘息)
kn-keyword=Bronchial asthma (気管支喘息)
END

start-ver=1.4
cd-journal=joma
no-vol=3
cd-vols=
no-issue=1
article-no=
start-page=145
end-page=156
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1998
dt-pub=19980114
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Consideration for the correlation between basicity of oxide glasses and chemical shift of O1s binding energy in XPS
kn-title=酸化物ガラスの塩基度とXPSによるO1ｓ束縛エネルギーの化学シフトの相関に関する考察
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Binding energy of O1s core electron measured in XPS is a candidate to determine new scale of Lewis basicity of oxide ion in glass. Some mathematical expressions for the basicity or XPS chemical shift, such as charge parameter and optical basicity, are compared with experimental O1s binding energy in binary alkali oxide glasses. The expressions so far in use need some modification in parameters. A new empirical expression introduced in this paper gives new concept and universal scale of basicity.
en-copyright=
kn-copyright=

en-aut-name=NanbaTokuro
en-aut-sei=Nanba
en-aut-mei=Tokuro
kn-aut-name=難波徳郎
kn-aut-sei=難波
kn-aut-mei=徳郎
aut-affil-num=1
ORCID=

en-aut-name=MiuraYoshinari
en-aut-sei=Miura
en-aut-mei=Yoshinari
kn-aut-name=三浦嘉也
kn-aut-sei=三浦
kn-aut-mei=嘉也
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=9
cd-vols=
no-issue=1
article-no=
start-page=69
end-page=73
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2004
dt-pub=20040227
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=CO(2) Fluxes Measured by Eddy Correlation and Aerodynamic Techniques
kn-title=傾度法と渦相関法で測定した二酸化炭素フラックスの比較
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=To elucidate the seasonal and inter-annual variation of CO(2) exchanges between the atmosphere and cultivated field in Japan, the CO(2) flux has been measured by the eddy correlation technique at the experimental farm of Agricultural Faculty, Okayama University since December in 1998. The CO(2) sensor, however, does not work under rainy conditions. The improved aerodynamic technique was developed and used to cover CO(2) flux data which were not collected. This technique gives reasonable CO(2) fluxes even in rainy days. The reliability of the technique was also confirmed by comparing CO(2) fluxes with those measured by the eddy correlation technique using data in fine weather conditions.
en-copyright=
kn-copyright=

en-aut-name=InoharaSachiko
en-aut-sei=Inohara
en-aut-mei=Sachiko
kn-aut-name=猪原幸子
kn-aut-sei=猪原
kn-aut-mei=幸子
aut-affil-num=1
ORCID=

en-aut-name=IwataToru
en-aut-sei=Iwata
en-aut-mei=Toru
kn-aut-name=岩田徹
kn-aut-sei=岩田
kn-aut-mei=徹
aut-affil-num=2
ORCID=

en-aut-name=OhtakiEiji
en-aut-sei=Ohtaki
en-aut-mei=Eiji
kn-aut-name=大滝英治
kn-aut-sei=大滝
kn-aut-mei=英治
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学
en-keyword=CO(2) flux
kn-keyword=CO(2) flux
en-keyword=Eddy correlation technique
kn-keyword=Eddy correlation technique
en-keyword=Aerodynamic techniques
kn-keyword=Aerodynamic techniques
en-keyword=Dimensionless profile
kn-keyword=Dimensionless profile
END

start-ver=1.4
cd-journal=joma
no-vol=3
cd-vols=
no-issue=1
article-no=
start-page=77
end-page=86
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2003
dt-pub=2003
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A Modeling of Cognitive Interpretation for Streetscape Images on VDT works
kn-title=VDTにおける画像評価認知特性のモデル化
en-subtitle=
kn-subtitle=
en-abstract=Our hypothesis is that the mode of subjective interpretation is based on abstract information process. In order to model the subjective interpretation for streetscape we analyze a relationship between adjectives and three graphical attributes color, derection, and position. We focus especially on the graphical descriptors such as Lab color system, its auto-correlation and rough image segmentation, which correspond to the graphical attributes. Our psychological experiment indicates that the subjective interpretation consists of "general evaluation","spatial", and "textual" factors. By analyzing the relationships between these three factors and the graphical descriptors, we find that each factor requires different graphical descriptors.
kn-abstract=本研究は、感性情報処理の研究としてVDTでのCG風景画印象評価で画像特徴量とその評価形容詞との対応関係を統計的に分析し認知構造を解析した。人間の経験的知識の違いにより、同じ刺激が違う認知効果を生む場合があるため、感性情報処理分野では個人の学習・認知経験により、同じ刺激が違う心理効果をうむ現象と画像特徴量との関係を分析している。その関係をモデル化することにより、画像特徴量をもとに、CGの評価を一般化することが可能になる。本研究では、街路の景観画像における植栽や面積（視野角）と「嗜好性」（好き、快いなどの形容詞）に相関関係があることを前提に分析・モデル化を行った。CGで作成した街路の景観画像をVDTで被験者に見せる心理実験の結果、いくつかの因子を抽出した。その分析から例えば、「広々感」という心理的効果には、空と道路の部分画像のみに関連しており、建物は従属的な要素となるという知見を得た。つまり、景象画像イメージは、必ずしも全体の画像は必要ないといえる。
en-copyright=
kn-copyright=

en-aut-name=YamaguchiYumi
en-aut-sei=Yamaguchi
en-aut-mei=Yumi
kn-aut-name=山口有美
kn-aut-sei=山口
kn-aut-mei=有美
aut-affil-num=1
ORCID=

en-aut-name=YamaguchiHaruhisa
en-aut-sei=Yamaguchi
en-aut-mei=Haruhisa
kn-aut-name=山口晴久
kn-aut-sei=山口
kn-aut-mei=晴久
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=VDT
kn-keyword=VDT
en-keyword=景象 (Landscape)
kn-keyword=景象 (Landscape)
en-keyword=認知特性 (Cognitive character)
kn-keyword=認知特性 (Cognitive character)
en-keyword=モデル化 (Modeling)
kn-keyword=モデル化 (Modeling)
END

start-ver=1.4
cd-journal=joma
no-vol=5
cd-vols=
no-issue=1
article-no=
start-page=109
end-page=117
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=2005
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An experiment on making "Belongingness to Classroom Group Scale" in high school.
kn-title=高等学校における学級集団帰属意識尺度作成の試み
en-subtitle=
kn-subtitle=
en-abstract=In this study, factors of "Belongingness to Classroom Group" among high school students of today were clarified and the correlations with "School Morale" and "Adaptation to School Life Scale" were also investigated under the structure of those factors. To begin with, items of factors of "Belongingness to Classroom Group" were collected from 145 students and 46 questionnaires were selected from concrete situations meeting their mental reality. After that, factor analysis was done on the scores and three factors "Acceptance from Class", "Class Unity" and "Obstacle to Belonging" were extracted. By doing the reliability analysis, it is understood that sufficient reliabilities have been confirmed on these three factors. Also, significant correlations were observed with all tests done in parallel and therefore we think that the construct validity has been supported.
kn-abstract=本研究では、現代の高校生における学級集団への帰属意識の要因を明確にし、その学級集団への帰属意識の要因の構造をもとに、高等学校における学級集団への帰属意識とスクールモラールや、学校生活適応感尺度との関連性について考察した。まず、145名の高校生から学級集団への帰属意識の規定要因についての項目を収集し、高校生の心的リアリティーに添った具体的場面での46の質問項目を選定した。学級集団への帰属意識尺度の得点について因子分析を行ったところ、「学級からの受容」、「学級のまとまり」、「帰属阻害感」の3因子が抽出された。各因子尺度の信頼性分析により、信頼性が確認された。また、全ての並行検査との間に有意な相関がみられることから構成概念妥当性が支持されたと考える。
en-copyright=
kn-copyright=

en-aut-name=HondaKimiko
en-aut-sei=Honda
en-aut-mei=Kimiko
kn-aut-name=本多公子
kn-aut-sei=本多
kn-aut-mei=公子
aut-affil-num=1
ORCID=

en-aut-name=InoueShoji
en-aut-sei=Inoue
en-aut-mei=Shoji
kn-aut-name=井上祥治
kn-aut-sei=井上
kn-aut-mei=祥治
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=帰属意識 (Belongingness)
kn-keyword=帰属意識 (Belongingness)
en-keyword=高等学校 (High School)
kn-keyword=高等学校 (High School)
en-keyword=学級集団 (Classroom Group)
kn-keyword=学級集団 (Classroom Group)
en-keyword=心的リアリティー (Mental Reality)
kn-keyword=心的リアリティー (Mental Reality)
END

start-ver=1.4
cd-journal=joma
no-vol=4
cd-vols=
no-issue=1
article-no=
start-page=89
end-page=96
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=1996
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Varietal Variation and Mechanism of Hull-cracked Grains in Two-rowed Barley
kn-title=二条オオムギにおける裂皮粒歩合の品種変異と発生機構
en-subtitle=
kn-subtitle=
en-abstract=二条カワムギ615品種を供試して裂皮粒（外頴が裂けて頴果が外から見えるもの）の発生歩合を調査した。全体の83％にあたる513品種では裂皮粒歩合が5％以下であったが、最高の品種は61％と高い値を示し、裂皮粒歩合の頻度分布は極めて歪んでいた。在来品種に比べて育成品種の中には裂皮粒歩合の高いものが多く、品種改善、特にビール麦としての品種改善の方向と裂皮粒の発生には関係があるとみられた。次に裂皮粒歩合の異なる二条オオムギ9品種を様々な条件で栽培し、裂皮粒歩合と1,000粒重を調査したところ、両者の環境相関係数は0.918と密接で、登熟の良い環境条件で裂皮粒が多発すること、すなわち、穀皮の大きさに比べて穀粒が大きくなり過ぎるような条件で裂皮粒が発生することが明らかにされた。
kn-abstract=Hull-cracked grain which causes low germinability and low malt extract has been observed in malting barley varieties mainly in the western part of Japan. In the first part of this study, more than 600 two-rowed barley varieties were examined for the percentage of hull-cracked grains. A markedly skewed frequency distribution pattern was observed for varietal variation of hull-cracked grain percentage. More than 80% of the varieties developed less than 5% hull-cracked grains, while a few of the varieties frequently developed the hull-cracked grains. The maximum hull-cracked grain percentage was as high as 61% in Yoshikei 16. Improved varieties developed hull-cracked grains more frequently than the local varieties, indicating varietal improvement indirectly caused the hull-cracked grains. In the second part, nine two-rowed varieties were grown in eight different conditions to analyze the mechanism of hull-cracking. Variances due to varieties, environment and their interaction were all statistically significant. Some of the varieties developed almost no hull-cracked grains throughout the environmental conditions examined, while others sharply responded to the environmental conditions. The environmental correlation coefficient between 1,000-kernel weight and hull-cracked grains was as high as 0.918, indicating that hull-cracked grains had developed under favorable ripening conditions.
en-copyright=
kn-copyright=

en-aut-name=KanataniRyoichi
en-aut-sei=Kanatani
en-aut-mei=Ryoichi
kn-aut-name=金谷良一
kn-aut-sei=金谷
kn-aut-mei=良一
aut-affil-num=1
ORCID=

en-aut-name=TakedaKazuyoshi
en-aut-sei=Takeda
en-aut-mei=Kazuyoshi
kn-aut-name=武田和義
kn-aut-sei=武田
kn-aut-mei=和義
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=Barley
kn-keyword=Barley
en-keyword=Varietal varietal
kn-keyword=Varietal varietal
en-keyword=Hull-crached grain
kn-keyword=Hull-crached grain
en-keyword=Ripening
kn-keyword=Ripening
END

start-ver=1.4
cd-journal=joma
no-vol=6
cd-vols=
no-issue=1
article-no=
start-page=13
end-page=19
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=1999
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Influence of climatic factors on "crop situation index" of wheat and barley in Okayama prefecture
kn-title=岡山県における小麦・大麦の作況指数変動に対する気象要素の影響
en-subtitle=
kn-subtitle=
en-abstract=1966-1995年の30年間について、岡山県の麦類の作況指数の変動と気象要素との関係について解析した。生育月別に作況指数と気象要素との関係を検討した結果、小麦では4月、6月の日照時間と正の相関、4月の降水量と負の相関が見られ、六条大麦では1月の降水日数、3月の気温、4月の日照時間と正の相関が、4月の降水量と負の相関が見られた。二条大麦では4月、5月の日照時間と正の相関、11月、4月の降水量と負の相関が認められた。このことから岡山県の麦の作況指数の年々の変動は、生育後期の日照時間と登熟期の降水量に最も深く関係していると考えられた。
kn-abstract=The influences of air temperature, precipitation, number of rainy days and sunshine duration on the crop situation index of wheat, six-rowed barley and two-rowed barley in Okayama prefecture were analyzed by using the data for the 30-year-period of 1966-1995. The crop situation index of these three crops showed high negative correlation with the precipitation in April and a positive correlation with sunshine duration in April. Precipitation over 150 mm or lesser sunshine duration under 190 hrs in April seems to reduce the yield of wheat and barley in Okayama.
en-copyright=
kn-copyright=

en-aut-name=KimuraKazuyoshi
en-aut-sei=Kimura
en-aut-mei=Kazuyoshi
kn-aut-name=木村和義
kn-aut-sei=木村
kn-aut-mei=和義
aut-affil-num=1
ORCID=

en-aut-name=TanakamaruShigemi
en-aut-sei=Tanakamaru
en-aut-mei=Shigemi
kn-aut-name=田中丸重美
kn-aut-sei=田中丸
kn-aut-mei=重美
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=Wheat
kn-keyword=Wheat
en-keyword=Barley
kn-keyword=Barley
en-keyword=Crop situation index
kn-keyword=Crop situation index
en-keyword=Precipitaion
kn-keyword=Precipitaion
en-keyword=Climatic factor
kn-keyword=Climatic factor
END

start-ver=1.4
cd-journal=joma
no-vol=6
cd-vols=
no-issue=1
article-no=
start-page=1
end-page=11
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=1999
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Estimation of Turbulent Fluxes by Gradient Method with Surface Temperatures of Rice Plant Canopy
kn-title=イネ群落表面温度を用いた傾度法による乱流輸送量の推定
en-subtitle=
kn-subtitle=
en-abstract=1997年夏季にイネ群落で、微細気象観測とともに、イネ群落の表面温度の測定を行った。得られた観測資料とイネ群落表面温度を用いてイネ群落上の乱流輸送量の推定を行った。結果は以下のように要約される。イネ群落上では、ほぼ全期間に亘って中立に近い安定な温度成層を形成し、日中には顕熱輸送量に比較して潜熱輸送量が格段に大きかった。熱映像温度計で測定されたイネ群落の表面温度から、群落上の顕熱輸送量と、植物の蒸散量と密接に関係する群落上の潜熱輸送量の推定を試みた。渦相関法で計算された顕熱輸送量とイネ群落表面温度から計算された顕熱輸送量と比較した。データのばらつきは大きいが、相関係数（R）の値は、0.79で、ほぼ1対1に対応していることが分かった。またイネ群落の表面で、水蒸気圧が飽和していると仮定し、イネ群落表面温度から、潜熱輸送量を推定すると、渦相関法で計算された潜熱輸送量よりも日中に2倍以上も過大評価されることが分かった。イネ群落直上で実測された水蒸気圧から、イネ群落表面の位置に相当する比湿を推定し、傾度法を用いて計算された潜熱輸送量が、渦相関法で得られた潜熱輸送量に、ほぼ1対1の対応をすることが分かった。また両者の間には、0.98と非常に高い相関関係が得られた。ここで行った計算には、尚幾つかの仮定が含まれているが、イネ群落の表面温度を用いて、顕熱、潜熱輸送量を推定する新たな評価法の一つとして今後利用できると期待される。
kn-abstract=Micrometeorological observations including turbulent fluxes and canopy surface temperatures were made in paddy in the summer of 1997. The sensible and latent heat fluxes were estimated by the gradient method under the assumption of similarity between the turbulent exchange coefficient for momentum and that for heat and water vapor. The surface temperatures measured by a thermal imager and water vapor pressures estimated from surface temperatures and relative humidity were used for temperature and water vapor at the height(d+z0) of U=0, where d is the displacement height, z0 the roughness length and U the mean wind velocity. The sensible and latent heat fluxes estimated by the gradient method depicted typical diurnal varietions. The turbulent fluxes by the present method and eddy correlation method showed fairly good agreement, especially for latent heat fluxes. These results confirmed that this method is a promising one.
en-copyright=
kn-copyright=

en-aut-name=MiyashitaKoichi
en-aut-sei=Miyashita
en-aut-mei=Koichi
kn-aut-name=宮下晃一
kn-aut-sei=宮下
kn-aut-mei=晃一
aut-affil-num=1
ORCID=

en-aut-name=MaitaniToshihiko
en-aut-sei=Maitani
en-aut-mei=Toshihiko
kn-aut-name=米谷俊彦
kn-aut-sei=米谷
kn-aut-mei=俊彦
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=Surface temperature
kn-keyword=Surface temperature
en-keyword=Rice plant canopy
kn-keyword=Rice plant canopy
en-keyword=Thermal imager
kn-keyword=Thermal imager
en-keyword=Turbulent fluxes
kn-keyword=Turbulent fluxes
END

start-ver=1.4
cd-journal=joma
no-vol=4
cd-vols=
no-issue=1
article-no=
start-page=49
end-page=58
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=1996
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=幼苗期と成熟期のオオムギ系統間における禾穀類アブラムシの密度とグラミン含量の関係
kn-title=Relationship between Gramine Concentration and Cereal Aphid Polulations in Seedling and Maturation Stages in Barley Lines
en-subtitle=
kn-subtitle=
en-abstract=オオムギ（Hordeum spontaneum及びH.vulgare）14系統の幼苗期と成熟期における、アブラムシの密度とインドールアルカロイド化合物であるグラミン含量の関係を調べた。温室内の幼苗では、グラミン含量に関わらずムギミドリアブラムシ（Schizaphis graminum）の寄生密度に有意差は認められなかった。一方、ムギクビレアブラムシ（Rhopalosiphum padi）の密度は、幼苗間で異なる場合もあった。圃場におけるアブラムシの寄生に対して、抵抗性は出穂期に顕著に現れた。アブラムシの寄生密度とグラミン含量の間には負の相関が認められた。成熟期のオオムギでは、グラミンの分解活性の高い感受性系統と比較して、抵抗性系統のグラミン含量は多く、特に野生系統では著しかった。
kn-abstract=The relationship between the indole alkaloid gramine concentration and aphid population was examined seedling and maturation stages in 14 barley lines of Hordeum spontaneum and H. unlgare. The density of Schizaphis graminum did not differ significantly with the gramine concentration in the seedling in the greenhouse. However, the population of Rhopalosiphum padi sometimes differed with the seedling. The plant resistance to the natural infestation of cereal aphids was obvious at the heading stage. There was a negative correlation between the high population density of aphids and gramine concentration. The gramine concentration was high in matured resistant resistant lines, especially wild lines, as compared with susceptible lines due to higher biodegradation activity.
en-copyright=
kn-copyright=

en-aut-name=MoharramipourSaeid
en-aut-sei=Moharramipour
en-aut-mei=Saeid
kn-aut-name=MoharramipourSaeid
kn-aut-sei=Moharramipour
kn-aut-mei=Saeid
aut-affil-num=1
ORCID=

en-aut-name=MurataShin-ichi
en-aut-sei=Murata
en-aut-mei=Shin-ichi
kn-aut-name=村田眞一
kn-aut-sei=村田
kn-aut-mei=眞一
aut-affil-num=2
ORCID=

en-aut-name=KanehisaKatsuo
en-aut-sei=Kanehisa
en-aut-mei=Katsuo
kn-aut-name=兼久勝夫
kn-aut-sei=兼久
kn-aut-mei=勝夫
aut-affil-num=3
ORCID=

en-aut-name=TsumukiHisaaki
en-aut-sei=Tsumuki
en-aut-mei=Hisaaki
kn-aut-name=積木久明
kn-aut-sei=積木
kn-aut-mei=久明
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学

affil-num=4
en-affil=
kn-affil=岡山大学
en-keyword=Barley
kn-keyword=Barley
en-keyword=Resistance
kn-keyword=Resistance
en-keyword=Gramine
kn-keyword=Gramine
en-keyword=Cereal aphids
kn-keyword=Cereal aphids
END

start-ver=1.4
cd-journal=joma
no-vol=4
cd-vols=
no-issue=1
article-no=
start-page=43
end-page=48
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=1996
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Relationship between Resistance to Cereal Aphids and Gramine Concentration in Beer Barley
kn-title=ビールムギのアブラムシ抵抗性とグラミン含量
en-subtitle=
kn-subtitle=
en-abstract=ビールムギを含む各種オオムギへのアブラムシの寄生数と、グラミン含量に注目して実験を行った。用いたビールムギは他のオオムギに比べ、アブラムシに比較的抵抗性を示すものが多く、極端な感受性を示す品種はなかった。特に、アサヒ5号やハルナ2条は野生系統H603（W603）に近い抵抗性を示した。ビールムギのグラミン含量はいずれも低く、アブラムシの寄生密度との間には負の相関が見られなかった。
kn-abstract=To beer barley resistance to cereal aphids, the relationship between the aphid density and gramine concentration was examined in various barley lines including beer barley cultivars. All beer barley cultivars tested were resistant or moderately resistant to the aphids, especially Asahi 5 and Haruna Nijo were similar to a wild line, H603 (W603), for checking resistant. However, these beer barleys contained much less gramine than the wild barley line, suggesting that another resistant factor(s) affects cereal aphid density.
en-copyright=
kn-copyright=

en-aut-name=TsumukiHisaaki
en-aut-sei=Tsumuki
en-aut-mei=Hisaaki
kn-aut-name=積木久明
kn-aut-sei=積木
kn-aut-mei=久明
aut-affil-num=1
ORCID=

en-aut-name=KasaharaToshihiko
en-aut-sei=Kasahara
en-aut-mei=Toshihiko
kn-aut-name=笠原敏彦
kn-aut-sei=笠原
kn-aut-mei=敏彦
aut-affil-num=2
ORCID=

en-aut-name=KanehisaKatsuo
en-aut-sei=Kanehisa
en-aut-mei=Katsuo
kn-aut-name=兼久勝夫
kn-aut-sei=兼久
kn-aut-mei=勝夫
aut-affil-num=3
ORCID=

en-aut-name=SaeidMoharramipour
en-aut-sei=Saeid
en-aut-mei=Moharramipour
kn-aut-name=SaeidMoharramipour
kn-aut-sei=Saeid
kn-aut-mei=Moharramipour
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学

affil-num=4
en-affil=
kn-affil=岡山大学
en-keyword=Beer barley
kn-keyword=Beer barley
en-keyword=Cereal aphid
kn-keyword=Cereal aphid
en-keyword=Resistance
kn-keyword=Resistance
en-keyword=Gramine
kn-keyword=Gramine
END

start-ver=1.4
cd-journal=joma
no-vol=3
cd-vols=
no-issue=1
article-no=
start-page=43
end-page=53
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1995
dt-pub=1995
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=大麦網斑病抵抗性の選抜効果
kn-title=Selection Effectiveness for the Resistance to Net Blotch in Barley
en-subtitle=
kn-subtitle=
en-abstract=抵抗性と罹病性の両親間の交雑に由来する2組のF2集団とその後代のF3系統を用いて、大麦網斑病における抵抗性の選抜効果を推定した。F3系統の平均値と分散から、病斑指数の分散が小さく、すでに固定した系統が多数存在したので、抵抗性は少数の遺伝子に支配されているとみられた。F2個体とF3系統間の親子相関、親子回帰およびF2の選抜差とF3系統の遺伝獲得量から遺伝率を推定したところ、2組の交雑組合せで抵抗性親の病斑指数は異なっていたにもかかわらず、3種類の遺伝率の推定値はいずれも0.6〜0.8の値を示した。遺伝率が高く、しかも関与する遺伝子数であるため、雑種集団で連続変異を示す場合の大麦網斑病抵抗性の選抜はF2からでも効果的とみられた。
kn-abstract=Selection effectiveness for the resistance to net blotch was estimated by using two sets of F2 and F3 populations derived from the crosses between resistant and susceptible parents. In every F2 and F3 population, disease ratings showed a continuous distribution. As many F3 lines with intermediate resistance had a smaller variance and homozygous genotype, the resistance might be controlled by a few genes. The heritabilities of the disease rating were estimated　by correlation coefficients and regression coefficients between each F2 plant and the descended F3 lines. Another estimate for heritability was calculated by the selection differential in the F2 plants and genetic gain in the F3 lines. Despite the different level of resistance in the resistant parents of the two crosses, the three kinds of heritabilities estimated were similar and ranged from 0.6 to 0.8. Because of the fewer number of genes controlling the disease resistance and the higher heritabilities, selection in a early generation may be effective for net blotch resistance in barlcy.
en-copyright=
kn-copyright=

en-aut-name=SatoKazuhiro
en-aut-sei=Sato
en-aut-mei=Kazuhiro
kn-aut-name=佐藤和広
kn-aut-sei=佐藤
kn-aut-mei=和広
aut-affil-num=1
ORCID=

en-aut-name=TakedaKazuyoshi
en-aut-sei=Takeda
en-aut-mei=Kazuyoshi
kn-aut-name=武田和義
kn-aut-sei=武田
kn-aut-mei=和義
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=Net blotch
kn-keyword=Net blotch
en-keyword=Pyrenophora teres
kn-keyword=Pyrenophora teres
en-keyword=Selection
kn-keyword=Selection
en-keyword=Barley
kn-keyword=Barley
en-keyword=Disease resistance
kn-keyword=Disease resistance
END

start-ver=1.4
cd-journal=joma
no-vol=2
cd-vols=
no-issue=1
article-no=
start-page=123
end-page=134
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=1994
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=カクヤリグサ科一年生雑草における数量分類学的研究
kn-title=Numerical Taxonomic Study in Annual Cyperaceous Weeds
en-subtitle=
kn-subtitle=
en-abstract=カヤツリグサ科の3種の雑草カヤツリグサ（C.microiria Steud.）12系統、コゴメガヤツリ（Cyperus iria L.）12系統およびチャガヤツリ（C.amuricus Maxim.）6系統を岡山県、鳥取県および東京都なら採集して倉敷で栽培し、形態的特性、バイオマスおよび種子生産性など21形質を調査した。各形質を分散分析したところ系統間差はいずれも有意であったが、種間の値は多くの形質で重複し、単一形質による種の判別は困難であった。21形質間の相関行列を主成分分析したところ、上位3主成分の累積寄与率は83％と大きく、第1主成分（37％）は小穂の形態と種子生産性、第2主成分（28％）は生長量、第3主成分（18％）は種子重と小穂密度とそれぞれ関係が深いとみられた。第1主成分と第3主成分によって供試30系統は3群に分けられ、各群はそれぞれの種と一致した。さらに、第2主成分と第3主成分によってカヤツリグサ種内の系統は主として生長量の異なる3群に分類できた。クラスター分析によって供試30系統は4つの大きな群に分けられた。一番目の群には、C.amuricusの全系統、二番目の群にはC.microiriaの3系統、三番目の群にはC.microiriaの残りの系統、および最後のクラスターにはC.iriaの全系統が含まれた。従って、C.microiriaha形態的および生態的形質において異なる2ないし3の生態型から成ると考えられた。このように数量分類学あるいは多変量解析はカヤツリグサ科の雑草の種間ならびに種内の分類に極めて有効な解析法であることが示された。
kn-abstract=Three species of Cyperaceous weeds, Cyperus iria (12 strains), C.　microiria(12 strains) and C. amuricus (6 strains), were collected from different sites of Okayama, Tottori and Tokyo prefectures, and various morphological characters, biomass and seed production were observed on the plants which were cultivated at Kurashiki. The analysis of variance showed a significant difference among the strains in each character. However, the species overlapped with each other in most morphological characters. Prinipal component analysis on the 21 characters showed that 83% of the total variation could be explained by the first three components: the first component (37%) was regarded as factors concerning spikelet and seed production; the second component (28%) was regarded as factors concerned the size of vegetative parts; the third component (18%) was largely affected by seed weight and floret density. Scatter diagram on the first and third principal components showed that the 30 strains of three species divided into three groups, and strains in each group correspond to the three species without exception. Based on the second and third principal components, strains of C. microiria were further divided into three sub-groups according to size of vegetative parts. Using the cluster analysis, 30 strains of these species were divided into four large clusters; the first was composed of C. amuricus strains, the second was of three strains of C. microiria, the third included the remaining strains of C. microiria, and the last cluster was composed of C. iria strains. It may be concluded that C. microiria is composed of two or three ecotypes which are different in morphological and reproductive traits.
en-copyright=
kn-copyright=

en-aut-name=Muhamad AhmadChozin
en-aut-sei=Muhamad Ahmad
en-aut-mei=Chozin
kn-aut-name=Muhamad AhmadChozin
kn-aut-sei=Muhamad Ahmad
kn-aut-mei=Chozin
aut-affil-num=1
ORCID=

en-aut-name=SatouKazuhiro
en-aut-sei=Satou
en-aut-mei=Kazuhiro
kn-aut-name=佐藤和広
kn-aut-sei=佐藤
kn-aut-mei=和広
aut-affil-num=2
ORCID=

en-aut-name=YasudaShozo
en-aut-sei=Yasuda
en-aut-mei=Shozo
kn-aut-name=安田昭三
kn-aut-sei=安田
kn-aut-mei=昭三
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学
en-keyword=Cyperus iria
kn-keyword=Cyperus iria
en-keyword=Cyperus microiria
kn-keyword=Cyperus microiria
en-keyword=Cyperus amuricus
kn-keyword=Cyperus amuricus
en-keyword=Numerical taxonomy
kn-keyword=Numerical taxonomy
en-keyword=Speciation
kn-keyword=Speciation
END

start-ver=1.4
cd-journal=joma
no-vol=2
cd-vols=
no-issue=1
article-no=
start-page=91
end-page=102
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=1994
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Sources of Resistance to Net Blotch in Barley Germplasm
kn-title=大麦網斑病における抵抗性遺伝資源
en-subtitle=
kn-subtitle=
en-abstract=日本ならびにカナダで採取した大麦網斑病菌4菌株を、岡山大学資源生物科学研究所大麦系統保存施設の保有する2,200あまりの品種に接種して、各菌株に対する抵抗性遺伝子源を評価すると共に病原性の分化を検討した。結果の概要は以下の通りである。1）3回にわたって44品種に4菌株を接種した予備試験の結果、病斑指数の品種変異は極めて大きく、品種の抵抗性に対する接種時期の影響は小さかった。2）供試4菌株に対するオオムギ品種の抵抗性の頻度分布はいずれも連続的で、そのピークは抵抗性側であった。各菌株間の病斑指数は有意な正の相関関係にあり、菌株間の病原性の分化は小さかった。3）各菌株に対する抵抗性遺伝資源はエチオピア、北アフリカおよび朝鮮半島に多かった。一方、日本で採取した2菌株に対する罹病性の品種はトルコおよびヨーロッパに多いのに対して、カナダで採取した菌株に対する罹病性の品種はネパールに多かった。また、ネパールに由来する品種の病斑指数は、日本の2菌株に対しては抵抗性と罹病性の2群に分かれたが、カナダの2菌株に対しては連続的な分布を示した。特に、カナダの菌株WRS102に対するネパール由来の品種の反応は、強度の抵抗性を示す品種がなく、ピークが罹病性側に片寄っており、日本の菌株に対する反応とは大きく異なった。4）日本で採取したK105とカナダで採取したWRS102の病斑指数の菌株間相関係数は、4菌株の組合せの中で最も小さく、K105とWRS102の病原性は多少分化していた。なお、K105に抵抗性でWRS102に罹病性の品種は25品種であり、そのうち20品種がネパール由来で、かつ、そのほとんどが小穂脱落性東亜型を示した。従ってK105に抵抗性でWRS102に罹病性の遺伝子は、ネパールの東亜型品種に偏在しているとみられる。
kn-abstract=Net blotch caused by a fungus Pyrenophora teres Drechs. is a common disease in barley. Its source of resistance has been screened by many researchers by field evaluations or seedling tests inoculating a single isolatc. Since the pathogcnic variation of isolates has been reported in net blotch, resistance of the varieties to the disease may be different among the isolates with different pathogenicities. In this study, the pathogenic variation was examined and the varietal variation of the resistance was evaluated by inoculating with four P. teres isolates collected from Japan and Canada to more than 2,200 barley varieties of the world collection preserved at the Barley Germplasm Center of Okayama University. A preliminary inoculation test showed that the disease rating was affected little by the inoculation seasons. Disease ratings of varieties showed a continuous variation with a single mode in the resistant range in each of the four isolates. However, the correlation coefficient between Japanese isolate K105 and Canadian isolate WRS102 was as low as 0.55, indicating a slight pathogenic differentiation between these isolates. Significant correlation coefficients (r=.55~.78) among the ratings of isolates indicated that the pathogenicity to the varieties was rather similar and that the pathogenic differentiation was small among the four isolates tested. In general, varieties from Ethiopia, North Africa and Korea were more resistant than those from other regions. Varieties from Turkey and Europe were susceptible to Japanese isolates, while Nepalese varieties were susceptible to Canadian isolates. Twenty of 25 varieties which were resistant to the isolate K105 but susceptible to the isolate WR102 were from Nepal and most of those were Oriental-type (Bt bt2) in brittleness of rachis. These findings revealed an example of regional concentration of resistant gene in net blotch.
en-copyright=
kn-copyright=

en-aut-name=SatoKazuhiro
en-aut-sei=Sato
en-aut-mei=Kazuhiro
kn-aut-name=佐藤和広
kn-aut-sei=佐藤
kn-aut-mei=和広
aut-affil-num=1
ORCID=

en-aut-name=TakedaKazuyoshi
en-aut-sei=Takeda
en-aut-mei=Kazuyoshi
kn-aut-name=武田和義
kn-aut-sei=武田
kn-aut-mei=和義
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=Barley
kn-keyword=Barley
en-keyword=Net blotch
kn-keyword=Net blotch
en-keyword=Disease resistance
kn-keyword=Disease resistance
en-keyword=Genetic resources
kn-keyword=Genetic resources
en-keyword=Race differentiation
kn-keyword=Race differentiation
END

start-ver=1.4
cd-journal=joma
no-vol=2
cd-vols=
no-issue=1
article-no=
start-page=79
end-page=89
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=1994
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Diallel Analysis for the Percentage of Grains with Hull Rupture in F2 Populations of Two-rowed Barley
kn-title=二条オオムギのF2集団における裂皮粒歩合のダイアレル分析
en-subtitle=
kn-subtitle=
en-abstract=二条オオムギにおける裂皮粒歩合の遺伝子を解析するために、裂皮粒歩合が大きく異なる8品種・系統の間で総当たりの交雑を行い、逆交雑を除く28組合せのF2集団とその親を供試して、裂皮粒歩合の遺伝子を調べた。片面ダイアレル分析の結果、裂皮粒歩合の遺伝子にはエピスタシスが認められず、単純な相加優性モデルが適合した。全体として裂皮粒歩合の低い方が部分優性と見られ、その平均優性度は0.97と推定された。裂皮粒歩合の遺伝率は狭義で0.58、広義で0.91と推定された。28組合せのF2集団の裂皮粒歩合はいずれの組合せにおいても連続的な分離を示し、また、超越分離が認められた。F2集団の平均値と両親品種の平均値の相関は高く、雑種集団における裂皮粒歩合は遺伝子の相加的な作用によって支配されていることが示唆された。28組合せのF2集団における裂皮粒歩合の表現型分散と遺伝分散の割合から推定した広義の遺伝率は0.43〜0.80（平均0.65）であった。
kn-abstract=Half diallel F2 populations crossed among eight two-rowed barley varieties with warious percentages of hull ruptured grains were raised to analyze the inheritance of the trait. The percentage of grains with hull rupture varied from 0 to 87% among the parents. The diallel analysis revealed the following: the trait was predominantly controlled by the additive genes, and the dominance effect of some parents was also significant. However, the epistatic effect of the genes was not significant. The average dominance was 0.97. The heritability value was estimated as 0.57 and 0.91 in a narrow and a broad sense, respectivelly. The percentage of grains with hull rupture showed continuous and transgressive segregations in 28 F2 populations derived from half diallel crosses among eight parents. Heritability of the trait in a broad sense was 0.43~0.80(0.65 on average) in 28 F2 populations.
en-copyright=
kn-copyright=

en-aut-name=WuJiri
en-aut-sei=Wu
en-aut-mei=Jiri
kn-aut-name=呉基日
kn-aut-sei=呉
kn-aut-mei=基日
aut-affil-num=1
ORCID=

en-aut-name=TakedaKazuyoshi
en-aut-sei=Takeda
en-aut-mei=Kazuyoshi
kn-aut-name=武田和義
kn-aut-sei=武田
kn-aut-mei=和義
aut-affil-num=2
ORCID=

en-aut-name=KanataniRyoichi
en-aut-sei=Kanatani
en-aut-mei=Ryoichi
kn-aut-name=金谷良一
kn-aut-sei=金谷
kn-aut-mei=良一
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学
en-keyword=Barley
kn-keyword=Barley
en-keyword=Grain quality
kn-keyword=Grain quality
en-keyword=Hull rupture
kn-keyword=Hull rupture
en-keyword=Diallel analysis
kn-keyword=Diallel analysis
en-keyword=Heritability
kn-keyword=Heritability
END

start-ver=1.4
cd-journal=joma
no-vol=2
cd-vols=
no-issue=1
article-no=
start-page=33
end-page=42
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=1994
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Comparison of Regenerating Ability of Calli Derived from Mature and Immature Embryos in Barley Varieties
kn-title=オオムギ品種における完熟胚および未熟胚由来カルスの再分化能の比較
en-subtitle=
kn-subtitle=
en-abstract=本研究では世界各地のオオムギ132品種を供試して完熟胚と未熟胚からのカルス誘導と再分化能について調査し、材料植物が有する遺伝要素と、外植片の違いが再分化能のどのように関与しているかを考察した。供試品種のほとんどがカルスを形成したが、全くカルスを形成しない品種もあった。エチオピアの品種にはカルス形成の悪いものが多くみられた。完熟胚培養系ならびに未熟胚培養系ともに供試品種によってカルスの増殖量に幅広い変異があり、カルスがほとんど形成されない品種から、著しく増殖する品種まであった。カルスの形態的特徴に関しては、完熟胚培養系ではほとんどの品種が水っぽいカルスを形成したのに対して、未熟胚培養系では品種によって、水っぽいタイプ、硬くしまったタイプ、もろく崩れやすいタイプの3タイプを形成し、両培養系間に大きな差異が認められた。完熟胚培養系の場合、再分化するのはほとんどが不定根であり、不定芽を再分化したのは日本の関東二条5号、ふじ二条および紫麦の3品種だけであった。一方、未熟胚培養系では、21.2％の品種が不定芽を再分化した。不定芽を再分化した品種は朝鮮半島や日本に多く、反対にエチオピアや西南アジアの品種には再分化するものが少なかった。供試品種における不定根の再分化率と不定芽の再分化率の間には相関関係はなかった。（r＝0.05）。両培養系の間ではカルス増殖量について相関関係はなく（r＝0.07）、不定根の再分化率については低い値ではあるが有意な正の相関があった（r＝0.24）。また、未熟胚培養系におけるカルス増殖量と不定芽の再分化率についても相関関係は認められなかった（r＝0.14）。二条品種と六条品種の間では、完熟胚培養系の不定根再分化率を除いて差は認められなかった。
kn-abstract=The callus forming ability and regenerating ability of the calli derived from mature and immature embryos of 132 barley varieties were examined. These materials were taken from a world-wide collection preserved at the Barley Germplasm Center of Okayama University. The callus forming ability varied widely according to genotype in both mature and immature embryos, but the varieties collected from Ethiopia showed low callus forming ability. Calli derived from mature embryos generally did not regenerate shoots, except for three Japanese varieties. The frequency of shoot regeneration from the calli derived from immature embryos was somewhat higher than that from those derived from mature embryos. Many of the Korean and Japanese varieties had a high shoot regenerating ability. However, few of the varieties from Ethiopia and Southwest Asia had a high shoot regenerating ability. No correlation was observed btween root regenerating ability and shoot regenerating ability of the varieties. No correlation was observed between callus proliferation and root regenerating ability between calli derived from mature and immature embryos. We could not find any difference in the shoot regenerating ability btween the two-rowed and six-rowed genotypes.
en-copyright=
kn-copyright=

en-aut-name=RikiishiKazuhide
en-aut-sei=Rikiishi
en-aut-mei=Kazuhide
kn-aut-name=力石和英
kn-aut-sei=力石
kn-aut-mei=和英
aut-affil-num=1
ORCID=

en-aut-name=YasudaShozo
en-aut-sei=Yasuda
en-aut-mei=Shozo
kn-aut-name=安田昭三
kn-aut-sei=安田
kn-aut-mei=昭三
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=Barley
kn-keyword=Barley
en-keyword=Tissue culture
kn-keyword=Tissue culture
en-keyword=Mature embryo
kn-keyword=Mature embryo
en-keyword=Immature embryo
kn-keyword=Immature embryo
en-keyword=Regenerating
kn-keyword=Regenerating
END

start-ver=1.4
cd-journal=joma
no-vol=1
cd-vols=
no-issue=2
article-no=
start-page=147
end-page=158
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1993
dt-pub=1993
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=日本とカナダの春播オオムギから採取した大麦網斑病菌株の病原性の変異
kn-title=Pathogenic Variation of Pyrenophora teres Isolates Collected from Japanese and Canadian Spring Barley
en-subtitle=
kn-subtitle=
en-abstract=北海道およびカナダの春播オオムギがら採取した22の大麦網斑病菌株（Pyrenophora teres Drechs.）を世界各地のオオムギ38品種に幼苗接種し、病斑指数によって病原性の変異を検討した。分散分析の結果、菌株の病原力ならびに品種の抵抗性には有意差が認められたが、菌株と品種の交互作用は統計的には有意でなかった。各菌株の反応をFinlay-Wilkinson（1963）の回帰分析によって解析したところ、北海道とカナダの菌株で病原性反応に差が認められた。この傾向はカナダの菌株のうち、通常のNet typeの菌株よりも斑点状病斑を示すSpot typeの菌株で顕著であった（Fig.1）。さらに、菌株と品種の交互作用を詳細に解析するために相互作用と相乗交互作用モデル（AMMIモデル）を適用して交互作用に関する主成分分析を行った結果、各菌株は日本のNet type、カナダのNet type、カナダのSpot typeの3群に分けられた（Fig.1）。各菌株について群間ならびに群内の相関係数を算出したところ（Table5）、Net typeの菌株相互の相関係数は0.601〜0.969と相対的に高かったが、一部の菌株と品種の組合わせでは抵抗性反応の逆転がみられた（Fig.4）。一方、Spot typeの菌株とNet typeの菌株の相関係数は0.302〜0.538と低く、両者の病原性は多少異なることが示された。このような一部の菌株と品種の間に認められる弱い交互作用は、抵抗性を支配する主働遺伝子の特異的な反応が、いわゆる圃場抵抗性を支配する微働遺伝子の作用によって修飾された結果と考えられる。
kn-abstract=Twenty-two isolates of Pyrenophora teres Drechs. collected from Japanese and Canadian spring barleys were inoculated to 38 barley varieties having various genetic backgrounds. The analysis of variance for the discase ratings showed that there were significant differences both in the virulence of isolates and the resistance of varieties. However, the interaction among isolates and varieties was not statistically significant. Both Finlay-Wilkinson regression analysis and principal component analysis by Additive Main effects and Multiplicative Interaction effects(AMMI)model classified the isolates into three groups,which were different in origins and sympton types. A spot tyte isolate was distinguished from net type isolates by its generally high virulence. A slight pathogenic differentiation was suggested between Japanese and Canadian net type isolates.
en-copyright=
kn-copyright=

en-aut-name=SatoKazuhiro
en-aut-sei=Sato
en-aut-mei=Kazuhiro
kn-aut-name=佐藤和広
kn-aut-sei=佐藤
kn-aut-mei=和広
aut-affil-num=1
ORCID=

en-aut-name=TakedaKazuyoshi
en-aut-sei=Takeda
en-aut-mei=Kazuyoshi
kn-aut-name=武田和義
kn-aut-sei=武田
kn-aut-mei=和義
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=Hordeum vulgare
kn-keyword=Hordeum vulgare
en-keyword=Pyrenophora teres
kn-keyword=Pyrenophora teres
en-keyword=Barley
kn-keyword=Barley
en-keyword=Net blotch
kn-keyword=Net blotch
en-keyword=Race differentiation
kn-keyword=Race differentiation
END

start-ver=1.4
cd-journal=joma
no-vol=60
cd-vols=
no-issue=569
article-no=
start-page=240
end-page=247
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=19940125
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A Fundamental Study of Heat-Transfer Enhancement and Flow-Drag Reduction in Tubes by Means of Wire Coil Insert : 1st Report, Characteristics of Flow Resistance and Heat Transfer in Tubes with Wire Coil Insert
kn-title=ワイヤーコイルを用いた円管内熱伝達促進と流動抵抗軽減に関する基礎研究 : 第1報,ワイヤーコイルによる管内流動抵抗および熱伝達特性
en-subtitle=
kn-subtitle=
en-abstract=円管内の対流熱伝達促進は、高粘性油の管内加熱・冷却操作、円管型太陽熱集熱器内循環水の昇温そして人工肺細血管内血流の温度制御などにみられる様々なタイプの熱交換器に関係するものである。特に、管内層流熱伝達の向上は、この種熱交換器のコンパクト化そして省エネルギーの立場から伝熱工学における重要な課題である。管内熱伝達促進に関する報告は数多いが、Berglesら、Shah＆Muellerそして棚澤により、その熱伝達促進技術が解説されている。管内熱伝達促進法を大別すると、（1）伝熱面近傍に比較的小さな突起物（台形、三角形、針状など）を設け、伝熱面近傍の境界層流れを撹乱する方法、（2）ねじれテープ等を管内に挿入し、主流を旋回させ、主流と管内壁近傍の流れを入れ換える方法、（3）比較的大きな円環などを管路に一定間隔で並べ、主流を撹乱させる方法などがある。いずれの熱伝達促進法においても、熱伝達の向上が認められ、熱交換器の小型化に寄与する。一方において、流動抵抗の増大となり、熱媒体のポンプが動力を含めた熱交換器システム全体でのエネルギー消費の増加を生み、省エネルギー機器としての熱交換器の性能評価に重要な問題を提起している現状にある。本研究では、比較的取扱いが容易なワイヤーコイルを伝熱促進体として管内に挿入した場合の熱伝達と流動抵抗特性を総合的に検討するものである。従来よりワイヤーコイルを伝熱促進体として用いた研究は、比較的素線径eの小さな（e＜1mm）もので、伝熱壁近傍流れの撹乱により伝熱促進を図り、コイルピッチPとコイル素線径eの比がP/e＝10前後で最大の熱伝達となる結果を得ているが、流動抵抗との相関関係を総合的に検討したのは少ないようである。Uttarwar＆Raoによりワイヤーコイル素線径e＝2〜3.4mmにて熱媒体として油を用いた低レイノルズ数（Re≦1000）の範囲で、伝熱促進効果の検討が唯一行われているが、流動抵抗の軽減までには言及していない。本研究においては、これらの現状に鑑み、比較的簡便に伝熱促進体の配置そして寸法の変更の容易なワイヤーコイルの特徴を生かした管内熱伝達促進と流動抵抗に関する実験を行い、管内レイニズル数、ワイヤーコイルピッチ、そしてコイル長さの効果を定量的に把握するものである。得られた結果は、今後この種ワイヤーコイルを用いた伝熱促進と流動抵抗軽減法の開発に大いに役立つものと思われる。
kn-abstract=Experimental studies have been carried out on heat-transfer enhancement and flow-drag reduction in a tube by means of wire coil insert. Heat-transfer rate and pressure-drop data of tubes with wire coil inserts have been taken under various experimental conditions of wire coil diameter and pitch, water flow rate and heating-surface temperature. The performance of these tubes with wire coil inserts has been evaluated concerning the increase of heat-transfer rate and flow resistance. The useful nondimensional correlations of heat-transfer rate and flow-resistance factor have been derived as functions of Reynolds number and wire coil pitch-to-diameter ratio.
en-copyright=
kn-copyright=

en-aut-name=InabaHideo
en-aut-sei=Inaba
en-aut-mei=Hideo
kn-aut-name=稲葉英男
kn-aut-sei=稲葉
kn-aut-mei=英男
aut-affil-num=1
ORCID=

en-aut-name=OzakiKoichi
en-aut-sei=Ozaki
en-aut-mei=Koichi
kn-aut-name=尾崎公一
kn-aut-sei=尾崎
kn-aut-mei=公一
aut-affil-num=2
ORCID=

en-aut-name=KanaokaShinichi
en-aut-sei=Kanaoka
en-aut-mei=Shinichi
kn-aut-name=金岡伸一
kn-aut-sei=金岡
kn-aut-mei=伸一
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学
en-keyword=Heat-Transfer Enhancement
kn-keyword=Heat-Transfer Enhancement
en-keyword=Flow-Drag Reduction
kn-keyword=Flow-Drag Reduction
en-keyword=Wire Coil
kn-keyword=Wire Coil
en-keyword=Turbulence Promoter
kn-keyword=Turbulence Promoter
en-keyword=Heat Exchanger
kn-keyword=Heat Exchanger
END

start-ver=1.4
cd-journal=joma
no-vol=62
cd-vols=
no-issue=594
article-no=
start-page=330
end-page=337
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=19960225
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Mixed Convection Heat Transfer in an Open Shallow Cavity Heated from Below and Packed with One-Step Arrangement of Spherical Particles : 2nd Report, Effect of Cavity Length
kn-title=比較的浅い底面加熱を受ける上部開放矩形くぼみに球状粒子を一段充填した場合の共存対流熱伝達 : 第2報, くぼみ長さの効果
en-subtitle=
kn-subtitle=
en-abstract=基盤上に配された電子素子群の冷却や、フィン群からの熱伝達、または果実等顆粒状農作物の保冷等、複雑な形状を有する物体からの熱伝達に関しては、その厳密な取扱いが非常に困難である。しかしながら、これら複雑な形状物を多孔質体として扱うことにより、比較的容易に伝熱解析できることも知られている。多孔質体層と純流体層よりなる系の対流熱伝達に関しては、従来より多数の研究が行われているがこれらの研究の大部分では、多孔質体を一様な均質体とみなした扱いがなされており、多孔質体表面近傍の流動・伝熱現象に関する詳細な議論はなされていない現状にある。しかしながら、文面に挙げた実例のように、比較的大きな物体より構成される系を多孔質体と見なした場合には、多孔質体表面付近の不均一性が伝熱特性に大きく影響されることが予測される。また、筆者らは、下面加熱を受ける比較的深い球状粒子充填矩形くぼみにおける共存対流熱伝達に関する基礎研究を行い、強制対流の効果は上部数段の粒子層に限定されることを見出しており、多孔質体表面近傍における熱伝達現象の解明が必要となっている。最近の研究では、二次元円柱群を多孔質体に見立て、N-S方程式等の基礎式を数値的に解析し、多孔質体表面近傍の流動・伝熱現象を検討する試みもなされているが、このような数値解析による方法では、安定な収束解が得られるのは非常に小さいレイノルズ数条件に限定される。本研究は、比較的実用的な空気流速範囲（数十cm/s〜数m/s）のもとで、不均質な多孔質層として一段配列球状粒子層を取り上げ、その熱伝達特性の解明を行うものである。また、本実験結果は、多孔質層の表面近傍における流動・伝熱特性の理解にも寄与するものと考えられる。前報では、長さL=90mmの底面加熱を受ける矩形くぼみ内に直径d=10mmの球状粒子を一段に配列した場合について実験的検討を行い、伝熱面上に配された球状粒子は、流れの攪拌効果を有する反面、伝熱面近傍の流れを抑制することや、熱伝導率の大きい球状粒子が拡大伝熱面として機能すること、さらに、くぼみ深さを小さくし、球状粒子層を流れの中に直接されした場合には、くぼみ上流端より粒子直径の4倍程度下流までの領域において伝熱特性の向上することが明らかとなった。本報では、前報にて観察された、くぼみ上流端より粒子直径の4倍程度下流までの領域にて、伝熱特性が流動挙動に大きく左右される事実に着目し、くぼみ長さLを、L=19.6mm、43mm、および90mmに設定した場合の共存対流伝達実験を行った。また、流れの可視化実験も行い、熱伝達と流動挙動の相関関係を、種々のくぼみ長さおよびくぼみ深さについて定性的に解明した。さらに、前報の結果も含めた全実験データを対象に、熱伝達特性の無次元整理をも行ったものである。
kn-abstract=Forced-natural-mixed convection heat transfer characteristics of a one-stage spherical particle layer in an air flow are investigated experimentally. The one-stage spherical particle layer is provided in a rectangular cavity having a heating bottom surface and is installed at the lower part of a rectangular air channel. Three types of spherical particles, which have almost the same diameter (about 10 mm) but different thermal conductivities, are tested. The cavity length is varied from 19.6 mm to 90 mm, and the cavity depth is varied between 0 mm and 10 mm. The variation of the heat transfer coefficient with the length of the heating surface can be explained by the flow behavior around the particle layer ; that is, the case of the zero cavity depth, the flow is suppressed by the particles within about three rows from the leading edge. Therefore, the heat transfer coefficient increases with a derease in the length of the heating surface. In the case with a shorter heating surface (about twice the diameter of the particle), a considerable increase in the heat transfer coefficient is achieved because the flow from the upstream runs through the particle layer. In the case of the cavity depth having almost the same value as the diameter of the particles, air flows over the particle layer and air near the cavity bottom is almost still. In this case, a decrease of the length of the heat transfer surface decreases the extent of the flow in the depth direction, and the heat transfer coefficient is also decreased. The heat transfer coefficient can be expressed as a nondimensional heat transfer correlation, where the effects of the cavity length, the cavity depth, the air velocity and the temperature difference between the air and the bottom surface of the cavity are taken into consideration.
en-copyright=
kn-copyright=

en-aut-name=OzakiKoichi
en-aut-sei=Ozaki
en-aut-mei=Koichi
kn-aut-name=尾崎公一
kn-aut-sei=尾崎
kn-aut-mei=公一
aut-affil-num=1
ORCID=

en-aut-name=InabaHideo
en-aut-sei=Inaba
en-aut-mei=Hideo
kn-aut-name=稲葉英男
kn-aut-sei=稲葉
kn-aut-mei=英男
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=Spherical Particle Layer
kn-keyword=Spherical Particle Layer
en-keyword=Forced Convection Heat Transfer
kn-keyword=Forced Convection Heat Transfer
en-keyword=Nonhomogeneous Porous Layer
kn-keyword=Nonhomogeneous Porous Layer
en-keyword=Effective Thermal Conductivity
kn-keyword=Effective Thermal Conductivity
END

start-ver=1.4
cd-journal=joma
no-vol=62
cd-vols=
no-issue=602
article-no=
start-page=172
end-page=179
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=19961025
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Fundamental Study on Latent Cold Heat Storage by means of Oil Droplets with Low Freezing Point : 3rd Report, Cold Heat Energy Release Characteristics of Direct-Contact Heat Exchange between Solidified Oil Droplets and Hot Air
kn-title=低凝固点油滴の凝固を利用した潜熱蓄冷熱に関する基礎研究 : 第3報, 粒状凝固潜熱蓄冷熱材と温空気の直接接触熱交換による放冷熱特性
en-subtitle=
kn-subtitle=
en-abstract=前報において、低温熱媒体槽中に非水溶液性油を噴射・凝固させることにより潜熱蓄冷熱を行う方法の提案を行った。このような潜熱蓄冷熱システムの放冷熱法として凝固した潜熱蓄冷熱材と暖かい空気を直接接触させて放冷熱を行う方法が考えられる。潜熱蓄冷熱材と熱媒体温空気が直接接触熱交換を行う場合、両者間の熱伝達効率が非常に高くなり、装置の高効率化および小型化が実現可能である。さらに、このような潜熱放冷熱法では、熱交換後の空気温度を蓄冷熱剤の融点に近づけることが可能であり、結果として必要とする空気温度に近い融点を持った潜熱蓄冷熱材を選ぶことにより、目的の熱交換後の空気温度を安定した状態で得られるという利点がある。しかしながら、この種の直接接触型潜熱放冷熱に関する研究は非常に少ない現状にある。本報告は、前報において述べた潜熱蓄冷熱材製造装置により得られた凝固油滴と水の混合物中に、下部から暖かい空気を吹き込み、微細な空気泡と凝固油滴の融解挙動および流通空気の熱交換特性について実験的に検討するものである。実験は無限に広い均一な凝固油滴層を対象とすることから、層最下部に多数の円形ノズルを均一に配列した分板を設置し、そこから温空気を層内に噴射した。このような直接接触熱交換法では、噴射空気泡により蓄冷熱充填層が流動するため、層内の温度場が均一となり、全ての凝固油滴において均一に融解が進行するという利点がある。さらに、凝固油滴と水の混合割合を変化させると凝固油滴層の流動状態をさまざまに変化させることが可能である。本報告は、実験因子としての入口空気温度、湿度および空気流量、そして凝固油滴混合水層高さが熱交換後の空気温度、湿度および潜熱放冷熱完了時間に及ぼす影響について実験的に検討し、これらの相関関係を実験式の形でまとめるものである。
kn-abstract=This paper deals with the cold latent heat energy release characteristics of direct-contact heat exchange between the solidified oil droplets [tetradecane, CH_3(CH_2)_<12>CH_3, melting point5.8℃] and hot air. Hot air is injected into the solidified oil droplet-water mixture layer from the distributor with a number of small circular nozzles. The solidified oil droplet-water mixture layer is fluidized by the air bubbles ascending in the layer, and the air bubbles are cooled from the layer by the direct-contact heat exchange. This paper deals with the characteristics of temperature and humidity of the outlet air from the layer, and time history of the cold heat energy release. The experiments were performed with respect to several experimental parameters, i. e., air flow rate, air temperature and humidity, and the amount of oil droplets and water in the mixture layer. Finally, some empirical correlations for the outlet air temperature and humidity and the finishing time of cold latent heat release were derived in terms of various nondimensional parameters.
en-copyright=
kn-copyright=

en-aut-name=InabaHideo
en-aut-sei=Inaba
en-aut-mei=Hideo
kn-aut-name=稲葉英男
kn-aut-sei=稲葉
kn-aut-mei=英男
aut-affil-num=1
ORCID=

en-aut-name=SatoKenji
en-aut-sei=Sato
en-aut-mei=Kenji
kn-aut-name=佐藤憲二
kn-aut-sei=佐藤
kn-aut-mei=憲二
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=Latent Cold Heat Release
kn-keyword=Latent Cold Heat Release
en-keyword=Direct-Contact Heat Exchange
kn-keyword=Direct-Contact Heat Exchange
en-keyword=Frozen Tetradecane Oil Droplet-Water Mixture
kn-keyword=Frozen Tetradecane Oil Droplet-Water Mixture
en-keyword=Temperature Efficiency
kn-keyword=Temperature Efficiency
en-keyword=Humidity
kn-keyword=Humidity
END

start-ver=1.4
cd-journal=joma
no-vol=67
cd-vols=
no-issue=654
article-no=
start-page=210
end-page=217
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2001
dt-pub=20010225
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Fundamental Study on Cold Energy Release by Direct Contact Heat Exchange between Ice Water Slurry and Hot Air
kn-title=氷水スラリーと温空気との直接接触熱交換による放冷に関する基礎研究
en-subtitle=
kn-subtitle=
en-abstract=近年、電力需要の急増傾向に対応すべく、夜間電力を利用した氷蓄熱システムの開発が盛んに行われ、ビル用空調を初めとして一般業務用空調にも製品として展開されてきている。その中で、蓄熱槽内にて氷と熱交換した冷水を利用側空調へ搬送させて冷房運転を行う水搬送方式に替わって、氷水スラリーを直接、利用側空調機へ搬送する氷水搬送技術の研究開発が行われている。このシステムは氷の潜熱を直接、利用側へ供給することにより、冷水搬送方法と比較して単位流量当たりの冷熱輸送能力が格段に増大するため、配管口径の縮小や輸送動力の低減が図れるものである。さらに、氷水スラリー搬送技術に加えて、搬送された氷水スラリーを冷房熱源として二重管式熱交換器の内管に流動させ、その外管に温水を流して採冷熱する方法や、角氷を充填層へ搬送して空気と直接接触熱交換させる採冷熱方法が提案されている。また、各種潜熱蓄冷熱材を被熟媒体とし、空気泡を熱媒体として両者を直接接触させて熱交換する直接接触熱交換に関する研究も行われている。上記直接接触熱交換では、噴射空気泡により潜熱蓄冷熱材が流動するため、潜熱蓄冷熱材の温度場が均一となり、潜熱蓄冷熱材と空気泡との熱交換が比較的均一に進行するという利点がある。しかしながら、氷水と空気との直接接触型潜熱放冷特性に関する研究が少ないのが現状である。氷水と空気との直接接触型放冷方式では、空気は氷水により冷却されるだけでなく、空気に含まれる水蒸気が氷水により凝縮されるため、冷却と除湿を同時に行える効果が期待できる。本研究は均一な氷水スラリー層を対象として、氷水スラリー層下部に多数の円形ノズルを均一に配列した分散板を設置し、そこから温空気を層内に噴射し、発生した空気泡と氷水スラリーとを直接接触熱交換させた場合の氷の融解挙動および通過空気の熱交換特性について実験的に検討するものである。その際の現象は粒状氷と水との混合割合や通過空気流速等を変化させることによりさまざまに変化させることが可能である。本研究では実験因子である流入空気温度、湿度、空気流量および氷質量充填率が、熱交換後の空気温度、湿度および潜熱放冷完了時間に及ぼす影響について実験的に検討し、これらの相関関係を実験式の形でまとめることを狙いとする。
kn-abstract=This paper has dealt with direct contact heat exchange characteristics between ice water slurry (average ice particle diameter : 3.10 mm) and hot air bubbles. The hot air bubbles ascending in the layer fluidized the ice water slurry layer, and the bubbles were cooled down directly by the ice water slurry. The following results were obtained from the experiment. In case of ice water slurry layer, the hot air bubbles fluidized the layer in earlier stage and heat exchange performance was higher than using only ice particles layer. The maximum temperature efficiency increased as Reynolds number Re increased because fluid in the layer became active and kept at the fixed value in the region of Re >__=900. Dehumidity efficiency increased as modified Stefan number and Re increased since the heat capacity of inlet air and heat transfer coefficient increased. Some empirical correlations for temperature efficiency, dehumidity efficiency and the completion time of latent cold heat release were derived in terms of various nondimensional parameters.
en-copyright=
kn-copyright=

en-aut-name=AoyamaShigeo
en-aut-sei=Aoyama
en-aut-mei=Shigeo
kn-aut-name=青山繁男
kn-aut-sei=青山
kn-aut-mei=繁男
aut-affil-num=1
ORCID=

en-aut-name=InabaHideo
en-aut-sei=Inaba
en-aut-mei=Hideo
kn-aut-name=稲葉英男
kn-aut-sei=稲葉
kn-aut-mei=英男
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=Slurry
kn-keyword=Slurry
en-keyword=Moist Air
kn-keyword=Moist Air
en-keyword=Packed Bed
kn-keyword=Packed Bed
en-keyword=Direct Contact Heat Exchange
kn-keyword=Direct Contact Heat Exchange
en-keyword=Temperature Efficiency
kn-keyword=Temperature Efficiency
en-keyword=Cold Energy Release
kn-keyword=Cold Energy Release
END

start-ver=1.4
cd-journal=joma
no-vol=85
cd-vols=
no-issue=1
article-no=
start-page=115
end-page=117
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=19960201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effect of Alternating Magnetic Field on Plant Growth
kn-title=変動磁場の植物生長に及ぼす影響
en-subtitle=
kn-subtitle=
en-abstract=戦後日本の農業は、農業機械の導入と化学薬品の投入により飛躍的にその生産性を高めてきた。今や、米の単位面積当たりの収量は世界有数であるといえる。しかしながら、多量のエネルギを圃場に投入し続けてきたことによるひずみは、農業生産の場のあちこちに現れてきており、環境問題の観点からも早急な対策を講じる必要がある。そこでまず検討すべき点は、現在の収量を維持しつつ、いかにして圃場への投入エネルギ量を低減していくかということである。そのため数々の手法が研究されているが、著者が注目しているのは微少エネルギの有効利用である。磁場を含む微少な環境因子の植物の生長に与える影響は、活発な論議がなされている。光、温度、水、栄養や大気環境等の環境因子と植物生長の相関についてに比べ、研究テーマとしてはそれほど大きく取り上げられてはこなかった。一方、篤農家を始めとする現場においては、例えば植物栽培に音楽を取り入れて生長促進を図るなど、微少環境の効果が決して小さくないことが実証されている。著者の現在までの研究でも、磁場等微少環境が植物の生長に対して何らかの影響を及ぼすことが確かめられており、これを定量化していくことがこれからの課題となっている。微少エネルギを植物の栽培に適応していくメリットとしては、安全かつ安価に植物の生長をコントロールできることがあげられる。現在の農業は大量のエネルギを植物に提供することで、増収や生長促進などの効果をあげてきた。確かに、作れば売れた時代はそれでもよかった。しかし、供給が需要を上回り、農家そのものが自由競争の原理の中での生き残りを迫られている今、新たな視点に立った農業生産方法の確立が必要とされている。高すぎる生産コストは市場での競争に不利であるし、化学薬品を大量に投入しての農産物は社会的に敬遠されつつある。ただし、値段が高いにも関わらず有機農法が社会的に支持を受けているのは、安全性を消費者がより重要視していると考えてよいだろう。したがって、微少エネルギの農業への導入は人に環境に優しいことを目指す、これからの農業大系に不可欠であるといえる。
kn-abstract=This paper describes the effect of alternating magnetic fields on plant germination. Experiments were conducted utilizing various frequencies and two states of polarity.Electromagnetic coils were used to generate the fields and 'Komatsuna' plants were chosen as subjects. The frequency was varied from 1 to 1000 Hz,at a fixed intensity of 5 Gauss. The magnetic polarity was controlled by reversing the current direction. Measured parameter was the germination rate. The results indicated that magnetic fields do influence plant germination, and that frequency of the fields is a more important factor in germination rates than polarity. Maximum germination rates,which were 20% higher than control rates,were obtained at around 10 Hz.
en-copyright=
kn-copyright=

en-aut-name=NambaKazuhiko
en-aut-sei=Namba
en-aut-mei=Kazuhiko
kn-aut-name=難波和彦
kn-aut-sei=難波
kn-aut-mei=和彦
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
en-keyword=magnetic stimulation
kn-keyword=magnetic stimulation
en-keyword=frequency
kn-keyword=frequency
en-keyword=germination
kn-keyword=germination
en-keyword=alternating magnetic field
kn-keyword=alternating magnetic field
END

start-ver=1.4
cd-journal=joma
no-vol=84
cd-vols=
no-issue=1
article-no=
start-page=25
end-page=30
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1995
dt-pub=19950201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effects of Air Movement on Respiration Rate,Heart Rate,Rectal Temperature,and Meat Production in Cattle
kn-title=牛の呼吸数，心搏数，体温および肉生産に対する気動の影響
en-subtitle=
kn-subtitle=
en-abstract=この研究は開始時平均9ヶ月令、体重375kg、終了時10ヶ月令、体重420kgのホルスタイン種去勢牛6頭を用い呼吸数、心搏数、体温に対する気動の効果を調べるために計画した。研究は7,8月で気温が28℃以上の日に実施した。自然の空気またはパッドアンドファン方式による冷気を送風機により牛舎内の牛の背部から1ｍの高さに設置したビニールフィルム管の送風口から牛の背部に送風した。本研究の送風は乾球温度および乾カタ冷却力と正相関、湿カタ冷却力と負相関があった。心搏数とエネルギー消費の関係に基づき牛肉生産に対する送風効果の概算評価を行った。5時間の送風により去勢牛1頭（400kg）当り、28〜32℃の環境では標準的肉質の牛肉60ｇ中のカロリーに相当するエネルギーの節約になった。
kn-abstract=The study was designed to investigate the effect of air movement on respiration rate,heart rate and rectal temperature,using six Holstein steers,avereging 9 months of age and 375.0kg of body weight at the beginning of the study and 10 monhts and 402kg at the end.The investigation was carried out in the days in July and August when abbient temperature were over 28℃.Either cooled air using a pad-and-fan sysytem or natural air was sent by electric fan to the back of each steer from distributing hole of vinyl film duct set 1 meter upside from the back of cattle in the shelter.The fannig caused a decrease in heart rate and respiration rate,but not in rectal temperature.Decrease in ambient temperature also caused a decrease in respiration rate.On reduction of the respiration rate,the fanning in the study had the effect same with that of decrease in ambieit temparature as much as 4℃.Fannnig using the wet pad system was more effective on reduction of respiration rate than the fanning without the pad.Respiration rate had a positive correlation with dry bulb temperature and dry kata cooling power,and a negative correlation with wet kata cooling power.On the basis of the relation between heart rate and energy con-sumption,the effect of the fanninng beaf production was estimated.The fanning for 5 hours a steer economized energy equiv alent to the Calorie in 60 grams of beaf with standard quality at ambient temperature of 28-32℃,and of beef in above 32℃.
en-copyright=
kn-copyright=

en-aut-name=WadaHiroshi
en-aut-sei=Wada
en-aut-mei=Hiroshi
kn-aut-name=和田宏
kn-aut-sei=和田
kn-aut-mei=宏
aut-affil-num=1
ORCID=

en-aut-name=YuharaMasataka
en-aut-sei=Yuhara
en-aut-mei=Masataka
kn-aut-name=湯原正高
kn-aut-sei=湯原
kn-aut-mei=正高
aut-affil-num=2
ORCID=

en-aut-name=OkushimaShiroh
en-aut-sei=Okushima
en-aut-mei=Shiroh
kn-aut-name=奥島史朗
kn-aut-sei=奥島
kn-aut-mei=史朗
aut-affil-num=3
ORCID=

en-aut-name=NakaiKatsuhiro
en-aut-sei=Nakai
en-aut-mei=Katsuhiro
kn-aut-name=中井捷宏
kn-aut-sei=中井
kn-aut-mei=捷宏
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学

affil-num=4
en-affil=
kn-affil=兵庫県柏原農業改良普及所
en-keyword=Steer
kn-keyword=Steer
en-keyword=Respiration rate
kn-keyword=Respiration rate
en-keyword=Heart rate
kn-keyword=Heart rate
en-keyword=Fanning
kn-keyword=Fanning
en-keyword=Beaf production
kn-keyword=Beaf production
END

start-ver=1.4
cd-journal=joma
no-vol=87
cd-vols=
no-issue=1
article-no=
start-page=169
end-page=173
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1998
dt-pub=199802
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Feeding Situation and the Meat Producing Characteristics of Jersey Cow in Hiruzen Province
kn-title=蒜山地域におけるジャージー種雌牛の飼育状況と産肉特性
en-subtitle=
kn-subtitle=
en-abstract=ジャージー種雌牛の食肉利用を推進する観点から、蒜山地域で行われている利用の状況ならびに食肉資源としての特性について検討した。その結果は次のとおりである。(1)蒜山酪農農業協同組合で飼育されているジャージー種のうち、酪農組合で食肉として処理、販売されるのは主としてさく去勢牛で、雌牛については1割程度しか利用されていなかった。(2)未経産牛と5歳齢以下の経産牛では、肥育飼養されていると推察された。(3)出荷体重と枝肉重の間に正の相関関係が認められ、出荷体重が大きいほど産肉牛が多かった。(4)ジャージー種はホルスタイン種よりも胸最長筋の脂肪含量が高く、脂肪交雑の入りやすい特性があると推察された。
kn-abstract=To promote utilization of Jersey cow's meat, we investigated the feeding situation and the ment producing characteristics of the Jersey breed in Hiruzen province. The results obtained were as follows: (1) Jersey meat is processed and sold by hiruzen Dairy Co-operation Association at Hiruzen. Most of the meat is occupied from steers, and cow meat comprises only 10%. (2) Fattening-feed performance was observed on non-delivered cows and delivered ones which were less than 5 years old. Dressing yield of the non-delivered cows was higher than that of delivered ones. (3) A linear correlation between body and carcass weight was found. Therefore, it was recommended that large cow production would bring profits in terms of economic gain. (4) The fat contents of longissimus muscle of the Jersey breed were higher than those of Holsteins, so it was considered they would probably have high marbling characteristics.
en-copyright=
kn-copyright=

en-aut-name=KurikiTakayoshi
en-aut-sei=Kuriki
en-aut-mei=Takayoshi
kn-aut-name=栗木隆吉
kn-aut-sei=栗木
kn-aut-mei=隆吉
aut-affil-num=1
ORCID=

en-aut-name=IzumimotoMasatoshi
en-aut-sei=Izumimoto
en-aut-mei=Masatoshi
kn-aut-name=泉本勝利
kn-aut-sei=泉本
kn-aut-mei=勝利
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=Jersey cow
kn-keyword=Jersey cow
en-keyword=meat production
kn-keyword=meat production
en-keyword=carcass quality
kn-keyword=carcass quality
END

start-ver=1.4
cd-journal=joma
no-vol=87
cd-vols=
no-issue=1
article-no=
start-page=35
end-page=41
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1998
dt-pub=199802
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=ヒマ種子カルス化に伴うアスパラギン結合型糖鎖の構造変化
kn-title=Changes in Asparagine-linked Sugar Chains of Glycoproteins in Ricinus communis Seeds during Callus Induction
en-subtitle=
kn-subtitle=
en-abstract=植物細胞の脱分化と糖蛋白質糖鎖（アスパラギン結合型糖鎖）の発現機構との相関を明らかにすることを目的とし、ヒマ種子から誘導したカルス中に発現されるアスパラギン結合型糖鎖（N-グルカン）の構造解析を行った。2,4-D処理によるカルス化誘導を行い、経時的に採取した組織からTriton X-100を含むHEPES緩衝液（ph7.4)で全糖蛋白質を抽出した。得られた糖蛋白質からヒドラジン分解によりN-グリカンを遊離された後、N-アセチル化、ピリジルアミン(PA)化により蛍光標識糖鎖を調製した。逆相およびサイズフラクショネーションHPLCによりPA-糖鎖を単一に精製後、糖鎖2次元マップ法により構造の同定を行った。その結果、カルス化に伴い、ハイマンノース型糖鎖(Man7-4GlcNAc2)の相対量が顕著に減少するのに対して、キシロース/フコース含有型糖鎖(
GlcNAclMan3FuclXyllGlcNAc2)の相対量が増加することが明らかになった。この現象は、植物細胞の脱分化に伴い、糖鎖プロセシングに関与するα-マンノシダーゼあるいはN-アセチルグリコサミン転移酵素の活性化が起こることを示唆するものと考えられる。
kn-abstract=Using glycotechnology procedures, structural changes in asparagine-linked sugar chains (N-glycans) of glycoproteins in Ricinus communis seeds during dedifferentiation (callus induction) have been explored. N-Glycans were released from the glycoproteins in the 2,4-D derived callus tissues by hydrazinolysis, and the resulting oligosaccharides were N-acetylated and coupled with 2-aminopyridine. Structures of the purified pyridylaminated (PA-) N-glycans could be deduced by two-dimensional (2D) sugar chain mapping method. Structural analysis clearly showed that the relative amount of high-mannose type N-glycans of the endospermic glycoproteins decreased as the plant cells dedifferentiated, while that of complex type N-glycans increased. this observation suggested that enhancement of expression and/or activation of certain α-mannosidase(s) involved in N-glycan processing could occur during dedifferentiation of plant cells.
en-copyright=
kn-copyright=

en-aut-name=KimuraYoshinobu
en-aut-sei=Kimura
en-aut-mei=Yoshinobu
kn-aut-name=木村吉伸
kn-aut-sei=木村
kn-aut-mei=吉伸
aut-affil-num=1
ORCID=

en-aut-name=TakagiShigeaki
en-aut-sei=Takagi
en-aut-mei=Shigeaki
kn-aut-name=高木茂明
kn-aut-sei=高木
kn-aut-mei=茂明
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=N-glycan structure
kn-keyword=N-glycan structure
en-keyword=plant glycoprotein
kn-keyword=plant glycoprotein
en-keyword=callus induction
kn-keyword=callus induction
en-keyword=Ricinus communis
kn-keyword=Ricinus communis
END

start-ver=1.4
cd-journal=joma
no-vol=88
cd-vols=
no-issue=1
article-no=
start-page=47
end-page=55
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=199902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effects of Cell Volume and Transplant Age in Cell Flat on Growth and Flowering after Transplanting in Antirrhinum majus L.and  Initial Growth after Transplanting in Matthiola incana R.Br.
kn-title=セル苗育苗におけるセル容量および移植時苗齢がキンギョソウの移植後の生長と開花ならびにストックの移植後の初期生長に及ぼす影響
en-subtitle=
kn-subtitle=
en-abstract=促成栽培したイチゴ’女峰’の’成り疲れ’と同時に発生する受精不良による奇形果発生要因を明らかにするため、イチゴ生産者の15棟のビニルハウスの花粉稔性の変化を調査し、気象要因、葉中無機養分および炭水化物濃度との関係について解析した。花粉稔性は、気温、日射量が低下し、着果負担が増大する1,2月に急激に低下したことから、奇形果発生の原因が花粉稔性の低下にあることが示された。花粉稔性と開花前1〜3日の日射量、当日の戸外の最低気温、葉中炭水化物濃度との間に高い相関が認められなかった。CO2施肥によって腋果房収穫開始期（1月）の花粉稔性が高まったことから、低日射と過重な着果負担による光合成産物不足が花粉稔性低下の大きな原因であると考えられた。
kn-abstract=Effects of Cell Volume and Transplant Age in Cell Flat on Growth and Flowering after Transplanting in Antirrhinum majus L.cv.Mangetsu and initial growth after transplanting in Matthiola incana R.Br.cv.White Dorse were studied.Seeds were sownin flats of two cell sizes (cylinders,448 and 220;volume6,12ml,respectively).At the same time each species were directly sown into wooden containers(38880ml).
The plants in cells were transplanted 32,37,42,47,52days old after sowing in A.majus and 18,25,32,39days old in M.incana.
The plants having formed root-balls could be found at 42 days and 47days after sowing in cell volume of 6ml and 12ml
respectively in A.majus.,and at 25days and 32days after sowing in cell volume of 6ml and 12ml respectively in M.incana.In both species shoot dry weight,root dry weight,stem length,node number and total leaf area were increaced with increaces in cell volume or transplant age.In A.majus flowering was delayed with increases in transplant age,especially in cell volume of 6ml.Cut flower quality suffered markedly with increaces in transplant age.
Node number was affected by cell volume but not by transplant age.In M.incana the growth 4weeks after transplanting of plants grown for 25days in cell volume of 12ml showed little difference compared with that of plants grown in the wooden container.
The results showed that for cell transplant production in both species,transplanting before 10days formde root-balls using cell volume of 12ml was optimal.Our investigation suggests that the suitable transplant age for work efficiency of transplanting may differ considerably from that for plant growth in both species.
en-copyright=
kn-copyright=

en-aut-name=GotoTanjuro
en-aut-sei=Goto
en-aut-mei=Tanjuro
kn-aut-name=後藤丹十郎
kn-aut-sei=後藤
kn-aut-mei=丹十郎
aut-affil-num=1
ORCID=

en-aut-name=KageyamaYoshihiro
en-aut-sei=Kageyama
en-aut-mei=Yoshihiro
kn-aut-name=景山詳弘
kn-aut-sei=景山
kn-aut-mei=詳弘
aut-affil-num=2
ORCID=

en-aut-name=KonishiKuniyoshi
en-aut-sei=Konishi
en-aut-mei=Kuniyoshi
kn-aut-name=小西国義
kn-aut-sei=小西
kn-aut-mei=国義
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学
en-keyword=cell volume
kn-keyword=cell volume
en-keyword=transplant age
kn-keyword=transplant age
en-keyword=root-balls
kn-keyword=root-balls
en-keyword=cut flower quality
kn-keyword=cut flower quality
en-keyword=dwarf plant
kn-keyword=dwarf plant
END

start-ver=1.4
cd-journal=joma
no-vol=88
cd-vols=
no-issue=1
article-no=
start-page=39
end-page=45
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=199902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Changes in Pollen Fertility of 'Nyoho' Strawberry in Relation to Light Intensity, Temperature and Leaf Carbohydrate and Mineral Concentration
kn-title=イチゴ’女峰’花粉稔性の変化と日射量、気温並びに体内炭水化物、無機養分濃度との関係
en-subtitle=
kn-subtitle=
en-abstract=促成栽培したイチゴ’女峰’の’成り疲れ’と同時に発生する受精不良による奇形果発生要因を明らかにするため、イチゴ生産者の15棟のビニルハウスの花粉稔性の変化を調査し、気象要因、葉中無機養分および炭水化物濃度との関係について解析した。花粉稔性は、気温、日射量が低下し、着果負担が増大する1,2月に急激に低下したことから、奇形果発生の原因が花粉稔性の低下にあることが示された。花粉稔性と開花前1〜3日の日射量、当日の戸外の最低気温、葉中炭水化物濃度との間に高い相関が認められなかった。CO2施肥によって腋果房収穫開始期（1月）の花粉稔性が高まったことから、低日射と過重な着果負担による光合成産物不足が花粉稔性低下の大きな原因であると考えられた。
kn-abstract=Changes in pollen fertility in forcing strawberry cv. Nyoho(Fragaria×ananassa Duch.)were investigated to clarify the factors affecting fruit malformation caused by poor fertilization which occurs with plant dwarfing and yeild decreace in February to March .Pollen were sampled from 15 greenhouses of strawberry growers,and relationships between pollen germination and climatic factors,mineral and carbohydrate concentration in leaves were analyzed.Pollen fertility decreased in January and February with decrease in
light intensity and outside air temprerature,and increace in
fruit load.It was suggested that the occurrence of fruit malfomation may be mainly caused by the decrease in pollen fetillity. There were highly significant relationships between the pollen fertility and light intensity in 1 to 3
days before anthesis,minimum outside air temperature on the day of anthesis,and carbohyrates,P,K and Ca concentration in  the leaves.No constant relationship could be found between polln fertility and leaf N concentration.Pollen fertility at the beginning of harvest for second inflorescence(January)was
improved with CO2 enrichment.These results indicate that the poor pollen development may result from the shortage of photosynthate caused by low light and fruit load.
en-copyright=
kn-copyright=

en-aut-name=YoshidaYuichi
en-aut-sei=Yoshida
en-aut-mei=Yuichi
kn-aut-name=吉田裕一
kn-aut-sei=吉田
kn-aut-mei=裕一
aut-affil-num=1
ORCID=

en-aut-name=TanimotoKeiichiro
en-aut-sei=Tanimoto
en-aut-mei=Keiichiro
kn-aut-name=谷本圭一郎
kn-aut-sei=谷本
kn-aut-mei=圭一郎
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=香川大学農学部
en-keyword=Fragaria×ananassa Duch.
kn-keyword=Fragaria×ananassa Duch.
en-keyword=pollen
kn-keyword=pollen
en-keyword=light energy
kn-keyword=light energy
en-keyword=nitorogen nutrition
kn-keyword=nitorogen nutrition
en-keyword=CO2 enrichment
kn-keyword=CO2 enrichment
END

start-ver=1.4
cd-journal=joma
no-vol=24
cd-vols=
no-issue=1
article-no=
start-page=9
end-page=11
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2003
dt-pub=200312
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=八浜農場でのCO2フラックス
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1997年のCOP3（京都会議)では、陸上生態系による炭素固定量を評価し、これを国別排出量から差し引くことが同意された。このため、陸域生態系における高精度の二酸化炭素、水蒸気、熱フラックス等の長期観測に基づいた科学的知見を集積し、対策を決めることが緊要課題となっている。このような社会的要請に応えるために、アメリカやヨーロッパ諸国では植生−大気相互作用の長期観測ネットワーク（EuroFlux, AmeriFlux)化が始まっている。日本でも1999年9月、日本を拠点としてアジアのネットワーク（AshiaFlux)の構築が決議された。我々は、AsiaFluxネットワークの一員として、岡山県南部の干拓農地に立地している岡山大学農学部附属農場において、二酸化炭素、水蒸気、熱フラックスの通年観測を実施している。本年度は、(1)岡山地方の一般的な農業形態をとっている八浜農場における炭素と熱収支の実態把握、(2)渦相関法では熱収支が閉じないという問題点の検討、という2つの課題に取り組んだ。
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=北垣順大
kn-aut-sei=北垣
kn-aut-mei=順大
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=牛川希望
kn-aut-sei=牛川
kn-aut-mei=希望
aut-affil-num=2
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=岩田徹
kn-aut-sei=岩田
kn-aut-mei=徹
aut-affil-num=3
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=大滝英治
kn-aut-sei=大滝
kn-aut-mei=英治
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学

affil-num=4
en-affil=
kn-affil=岡山大学
en-keyword=八浜農場
kn-keyword=八浜農場
en-keyword=CO2フラックス
kn-keyword=CO2フラックス
en-keyword=COP3
kn-keyword=COP3
END

start-ver=1.4
cd-journal=joma
no-vol=25
cd-vols=
no-issue=1
article-no=
start-page=7
end-page=10
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2003
dt-pub=200312
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=八浜農場での熱収支
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=太陽から地表面に与えられた熱エネルギーは、顕熱や潜熱に変換されるが、地表面の種類や状態によってその配分比率が変わり、大気に及ぼす効果は異なる。従来から、いろいろな地表面において熱収支に関する研究が行われており、裸地面ではその収支は釣り合っているとされている（例えば、古藤田、1984；近藤、1995；Seo、1958)。しかし、森林などの複雑地形状で渦相関法を用いた測定では熱収支が閉じないと指摘されている（Finnigan et al.,2003)。我々の研究目的は、裸地と森林の中間的な粗度面である水稲群落圃場での熱収支を明らかにすることである。特に、圃場の土壌及び灌漑水の貯熱量に注目し解析を行った。
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=楊冬梅
kn-aut-sei=楊
kn-aut-mei=冬梅
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=岩田徹
kn-aut-sei=岩田
kn-aut-mei=徹
aut-affil-num=2
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=三浦健志
kn-aut-sei=三浦
kn-aut-mei=健志
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学
en-keyword=八浜
kn-keyword=八浜
en-keyword=熱収支
kn-keyword=熱収支
en-keyword=水稲群落圃場
kn-keyword=水稲群落圃場
END

start-ver=1.4
cd-journal=joma
no-vol=134
cd-vols=
no-issue=
article-no=
start-page=85
end-page=91
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2007
dt-pub=20070315
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Nutritional Status and Competitive Ability in Wheelechair Basketball Players
kn-title=車椅子バスケットボール選手に対するアンケート調査
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=本研究では、障害者スポーツの中でも最も人気が高く、競技人口の多い競技のうちの１つである車椅子バスケットボール選手を対象にアンケート調査を実施し、競技力向上の手がかりと食生活に関する調査を行い、障害者スポーツ選手のサポート・食生活のあり方について検討することを目的とした。その結果、1)車椅子バスケットボール実施者、競技水準が上がるにつれて年齢は下がっている傾向がみられた、2)車椅子バスケットボール実施理由を「競技志向」、「健康志向」、「きっかけづくり」と3因子に分類したとき「競技志向」と競技水準には有意な相関がみられた、3)「栄養・食生活に関するサポート」と競技水準とについて有意な相関がみられ、競技水準の高いものが栄養・食生活に関する意識が高い傾向がみられた。
en-copyright=
kn-copyright=

en-aut-name=MiuraKoji
en-aut-sei=Miura
en-aut-mei=Koji
kn-aut-name=三浦孝仁
kn-aut-sei=三浦
kn-aut-mei=孝仁
aut-affil-num=1
ORCID=

en-aut-name=MatsuiKumiko
en-aut-sei=Matsui
en-aut-mei=Kumiko
kn-aut-name=松井久美子
kn-aut-sei=松井
kn-aut-mei=久美子
aut-affil-num=2
ORCID=

en-aut-name=KatayamaKeiko
en-aut-sei=Katayama
en-aut-mei=Keiko
kn-aut-name=片山敬子
kn-aut-sei=片山
kn-aut-mei=敬子
aut-affil-num=3
ORCID=

en-aut-name=OchiEisuke
en-aut-sei=Ochi
en-aut-mei=Eisuke
kn-aut-name=越智英輔
kn-aut-sei=越智
kn-aut-mei=英輔
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学

affil-num=4
en-affil=
kn-affil=岡山大学
en-keyword=車椅子バスケットボール
kn-keyword=車椅子バスケットボール
en-keyword=アンケート
kn-keyword=アンケート
en-keyword=食生活
kn-keyword=食生活
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=1
article-no=
start-page=51
end-page=57
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2004
dt-pub=200402
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Cultivar Differences in Palatability and Physicochemical Properties of Cooked Rice Cultivated in Okayama Prefecture
kn-title=岡山県における主要水稲品種の食味と理化学的特性
en-subtitle=
kn-subtitle=
en-abstract=岡山県における米の食味に関する基礎的知見を得ることを目的として，岡山県の主要水稲品種，コシヒカリ・ヒノヒカリ・朝日・アケボノと日本晴を供試し，岡山・八浜・倉敷の各水田において，異なる施肥段階を設定して栽培を行い，米飯の食味と理化学的特性を調査した．その結果，５品種間ではヒノヒカリが食味官能評価の全項目において最も優れた．朝日は総合評価・粘りでコシヒカリと同等の値を示し，味はコシヒカリよりも優れ，硬さはアケボノよりも硬いことが認められた．３試験地間では長期間無施肥栽培を行っている倉敷水田の食味が優れ，これには土壌窒素含有率が低く，玄米に蓄積されるタンパク質量が少ないことが関係すると考えられた．施肥レベル間では，施肥量の増加に伴い，いずれの品種においても食味値が低下する傾向が認められた．全品種込みで食味の総合評価と精米のタンパク質含有率との間には密接な正の相関関係が認められたが，アミロース含有率との間には直接的な関係は認められなかった．またアミログラム特性の最高粘度とブレークダウンにおいても直線関係は認められなかった．テクスチャー特性においては，Ｈ/−ＨとＨ/A３と総合評価との間に密接な負の相関関係が認められた．このことから，岡山県において，良食味米生産を行うためには，精米の窒素含有率に着目して，収益性を考慮しつつ，食味低下の小さい栽培指針を，それぞれの地域の土壌条件に対応して示すことが必要であると考えられた．
kn-abstract=The palatability and physicochemical properties of cooked rice, in the cultivars Koshihikari, Hinohikari, Asahi and Akebono, which are commonly cultivated in Okayama prefecture were compared with standard cultivar Nipponbare, in the paddy fields of Okayama, Hachihama and Kurashiki Farm of Okayama University. The rate of fertilizer application on those properties in Okayama Farm was also examined. Hinohikari beat the other four cultivars in all tests of palatability. Asahi tested better than Koshihikari, and was harder than Akebono, but in overall eating quality and stikiness it was almost indistinguishable from Koshihikari. The palatability values of cooked rice produced at Kurashiki farm, in which fertilizers were not applied for 25 years, were the highest out of the three locations. It was considered that the protein content of milled rice was lowest in Kurashiki due to the lower nitrogen content of the soil there. In all cultivars the higher the application rate of fertilizer, the lower the values of palatability due to the increase in nitrogen content of the milled rice, but not with amylose content or amylographic characteristics, i.e., maximum viscosity and breakdown values. The textural characteristics, i.e., the ratio of hardness/stichiness and hardness/adhesiveness were negatively correlated with overall eating quality. The results suggested that it is important to create manuals for the production of rice with good eating quality at each location in consideration of the nitrogen content of milled rice and the yield of brown rice.
en-copyright=
kn-copyright=

en-aut-name=YamamotoEma
en-aut-sei=Yamamoto
en-aut-mei=Ema
kn-aut-name=山本永真
kn-aut-sei=山本
kn-aut-mei=永真
aut-affil-num=1
ORCID=

en-aut-name=MatsueYuji
en-aut-sei=Matsue
en-aut-mei=Yuji
kn-aut-name=松江勇次
kn-aut-sei=松江
kn-aut-mei=勇次
aut-affil-num=2
ORCID=

en-aut-name=SaitohKuniyuki
en-aut-sei=Saitoh
en-aut-mei=Kuniyuki
kn-aut-name=齊藤邦行
kn-aut-sei=齊藤
kn-aut-mei=邦行
aut-affil-num=3
ORCID=

en-aut-name=KurodaToshiro
en-aut-sei=Kuroda
en-aut-mei=Toshiro
kn-aut-name=黒田俊郎
kn-aut-sei=黒田
kn-aut-mei=俊郎
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=福岡県農業総合試験場

affil-num=3
en-affil=
kn-affil=岡山大学

affil-num=4
en-affil=
kn-affil=岡山大学
en-keyword=Fertilizer application
kn-keyword=Fertilizer application
en-keyword=Okayama Prefecture
kn-keyword=Okayama Prefecture
en-keyword=Palatability
kn-keyword=Palatability
en-keyword=Protein content
kn-keyword=Protein content
en-keyword=Rice
kn-keyword=Rice
END

start-ver=1.4
cd-journal=joma
no-vol=95
cd-vols=
no-issue=1
article-no=
start-page=87
end-page=91
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2006
dt-pub=200602
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Isothiocyanates as Novel Cancer Chemopreventive Agents and Their Underlying Molecular Mechanisms
kn-title=イソチオシアネートによるがんの化学予防の可能性
en-subtitle=
kn-subtitle=
en-abstract=野菜全般の摂取と健康状態に関する疫学的研究は，近年数多く報告されており，様々な疾患リスクの低減だけでなく，通常の健康状態に関しても野菜の有効・有用性が示唆されている．その一方で，食生活の欧米化の着実な進行から，肉食・魚介類の順調な消費の伸びに対し，野菜消費量が減少の一途を辿っている．特に，若年齢層を中心とした世代の野菜消費量の減少が顕著であり，生活習慣病の若年齢化との相関から，社会問題として注目を浴びつつある．例えば，野菜を十分に摂取出来れば所要量の確保が容易なビタミンである葉酸であるが，新生児の神経管閉鎖障害症の最近の増加から，妊娠初期の女性の摂取不足に厚生労働省が警鐘を鳴らしている．また，昨今の栄養・健康情報の氾濫とサプリメント（栄養補助食品，健康補助食品）市場の急激な成長により，サプリメントを利用しておけば普段の食生活はないがしろにしても構わないという風潮に歯止めがかからなくなっている．野菜の摂取を推奨していくためには，人の健康と野菜摂取との関連を科学的かつ体系的に解明・整理にすることが今一度必要である．野菜中に含まれる，より具体的な機能性成分の性質や分布を正確に理解し，健康維持や疾病予防への寄与を明らかにすることができれば，より健全な「日本型食生活」への回帰を目指した野菜の消費拡大の一助となることはいうまでもない．それゆえ，これからの食品機能の基盤的研究が果たす役割は極めて重要であるといえる．食品機能の基盤的研究のなかで，現在最も体系的に進んでいる研究分野として，がん予防に関する研究が挙げられる．発がんの原因物質の排除と発がん抑制物質の積極的な摂取が「がんの化学予防」の基本戦略であるが，数多くの疫学的研究や動物実験の成果から，野菜や果物などの植物性食品の摂取が予防に有効であるといわれて久しい．特に，1990年代に米国で「デザイナーフーズ」計画がスタートしたことをきっかけとして，十数余年にわたるこれまでの研究は，がん予防に有望な素材・成分の化学的解明，動物実験成績や基本的作用機構に関する知見の蓄積だけでなく，その他の疾病をターゲットとし
た食品機能研究の進展に大きく寄与してきた．その一方で，β-カロテンのヒト介入試験での不成功から，食品成分による疾病予防法確立への道は決して平坦なものではないことも浮彫りとなった．現在，がんの化学予防研究は，ヒトにおける有効性をどのように評価して行くかを共通課題とし，体内動態や遺伝子発現の網羅的，体系的解析などのより詳細な分子レベルでの研究へと進展を遂げつつあり，筆者も例に漏れず研究標的をシフトしてきた．また，これまで有効とされてきた素材・成分の再評価，品種改良などによる有効成分（活性及び含量の）増強素材の開発，より偏りの少ない食事・栄養指導など，網羅すべき課題の広がりにより，食品化学分野は新展開の局面を迎えている
kn-abstract=A promising group of compounds that have a chemopreventive property are isothiocyanates (ITCs). ITCs have been shown to induce apoptosi in various cancer cell lines and experimental rodents. Multiple signaltransduction pathways as well as apoptosis intermediates have been also posturalted. We recently clarified the moleculae mechanism underlying the relationship between cell cycle arrest ad apoptosis induced by benzyl isothiocyanate(BITC), a major ITC compound isolated from papaya. The exposure of cells to BITC resulted in the inhibition of the G<sub>2</sub>/M progression that coincided with not only hte up-regulated expression of the G<sub>2</sub>/M cell cycle arrest-regulating genes but also the apoptosis induction. Conversely, treatment with an excessive concentration of BITC resulted in an abortive apoptotic pathway without DNA ladder formation. This commentary will review the biological impact of cell death induction by BITC as well as other ITCs and the involved signal transduction pathways.
en-copyright=
kn-copyright=

en-aut-name=NakamuraYoshimasa
en-aut-sei=Nakamura
en-aut-mei=Yoshimasa
kn-aut-name=中村宣督
kn-aut-sei=中村
kn-aut-mei=宣督
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
en-keyword=isothiocyanates
kn-keyword=isothiocyanates
en-keyword=cancer chemoprevention
kn-keyword=cancer chemoprevention
en-keyword=apoptosis
kn-keyword=apoptosis
en-keyword=cell cycle arrest
kn-keyword=cell cycle arrest
en-keyword=necrosis
kn-keyword=necrosis
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2003
dt-pub=20030930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=肝切除患者における肝線維化,再生とTc-99m-GSAシンチグラフィの相関
kn-title=Comparison of Tc-99m-GSA scintigraphy with hepatic fibrosis and regeneration in patients, with hepatectomy
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=IguchiToshihiro
en-aut-sei=Iguchi
en-aut-mei=Toshihiro
kn-aut-name=生口俊浩
kn-aut-sei=生口
kn-aut-mei=俊浩
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=20050325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=再灌流に成功した前壁急性心筋梗塞患者の血漿osteopontin･レベルの経時的変化:左室容積と機能の相関
kn-title=Time-dependent Changes of Plasma Osteopontin Levels in Patients with Anterior Wall Acute Myocardial Infarction after Successful Reperfusion: Correlation with Left Ventricular Volumes and Function
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=SuezawaChisato
en-aut-sei=Suezawa
en-aut-mei=Chisato
kn-aut-name=末澤知聡
kn-aut-sei=末澤
kn-aut-mei=知聡
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=20050325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=再疎通療法成功後の急性心筋梗塞において,循環白血球数は,梗塞のリスク領域とは独立して､左心室指数と相関する
kn-title=Circulating white blood cell count correlates with left ventricular indices independently of the extent of risk area for myocardial infarction after successful reperfusion
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=UesugiTadahisa
en-aut-sei=Uesugi
en-aut-mei=Tadahisa
kn-aut-name=上杉忠久
kn-aut-sei=上杉
kn-aut-mei=忠久
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=3/4filledバンドを有する擬2次元有機伝導体の低温構造と絶縁相
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=本研究では，有機分子BEDT-TTFからなる有機伝導体のうち，バンドが3/4filledであり，2次元的なフェルミ面を持ちながら低温で非金属状態となる物質を含む2タイプの結晶構造に関してX線回折の手法により実験をおこない，電子状態の研究を行った．κ型結晶κ-(BEDT-TTF)(2)Cu[N(CN))(2)]X[X =Cl, Br]では，BEDT-TFF分子の2量体(ダイマー)化によってバンドが分裂し，伝導バンドは実効的に1/2 filledと見なせる．これまで提案されてきた"ダイマーモデル"では，ダイマーを1サイトと考え，ダイマー上のon site Coulomb反発U(eff)が2量体化の程度に左右され，系がMott絶縁体となるか否かはU(eff)と伝導バンドの幅W(u)との比で決定されるとしていたが，構造的な証拠が存在しなかった．X=Cl, Brの水素(h8)体，重水素置換(d8) 体について低温で精密結晶構造解析をおこない，"ダイマーモデル"が系統的に成り立つかを研究した．この結果，結晶構造の温度変化が大きく，低温構造が本質的に重要であることが明らかになった．つまり，低温で反強磁性体となるととが知られているCl塩では構造不安定性が小さく順調に格子が熱収縮し，低温でダイマー性が強くなる．これに対し，低温で金属から超伝導体になるBr塩では，2種類の構造変化が200〜220K近辺，80K付近で生じる．前者ではきわめて弱い2c周期の変調構造が陰イオン間の相互作用により形成されるが，層間のカップリングが弱く2次元的な秩序に留まる．BEDT-TTF分子にはほとんど影響がなく電子状態への影響は小さい．しかし，80Kでは陰イオンとBEDT-TTFのフラストレーションにより，BEDT-TTFにも配置の変化が起こりon site Coulomb反発U(eff)の程度に影響を与える．この2種類の変化は独立であり，そのいずれもが，これまでの予想とは異なり，BEDT-TTF終端のエチレン基の配向度とは直接関連していない．今回，低温で得られた原子座標と既存の原子座標とを用いてバンド計算をおこない比較した結果，(1)h8体のBr塩を除き，絶縁体から金属まで，低温構造から見積もられるU(eff)/Wで整理され，ダイマーモデルで理解できること，(2)Cl塩とBr塩とではハロゲン原子の置換が80Kの構造変化の有無をひき起こし， 80K以下で2量体化の程度が大きく拡大しU(eff)に差が生ずること，および，(3)d8-Br塩の急冷状態が絶縁体なのはU(eff)の差ではなく，80Kの構造変化が不完全になりダイマー問の移動積分(つまりはバンド幅)が小さくなるためであることがわかった．h8-Brでは，d8-Brの急冷状態とほぼ同じ傾向が観測された．これは徐冷時には金属(11.6K以下で超伝導)になることと一見矛盾するが，発表されているh8体のBr塩の構造データは，温度因子が低温でも大きく，構造的には急冷相であると考えられるので，実はダイマーモデルでも理解可能である．第2の物質系であるθ-(BEDT-TTF)(2)CsCo(SCN)(4)では，金属状態ではBEDT-TTF分子の2量体化がなく，したがって単一の3/4 filledバンドをもち，フェルミ面も常圧では楕円型に近い単純な形状をしている．アニオン中の金属原子を化学置換したものでは金属ー絶縁体転移温度が系統的に増加する．この化学置換により分子間の2面角が変化する結果バンド幅Wが減少することから，絶縁相がMott相であり，低温では2量体が形成されると予想されていた．たしかにθ-(BEDT-TTF)(2)CsCo(SCN)(4)の低温非金属状態では2倍の超格子構造が形成されることが発見されたが，その振幅，相関長から，ダイマーモデルのMott相としての取り扱いは困難であり，むしろ最近接クーロン反発の効果による電荷秩序相と考えた方よいことがわかった．なお，物理的な圧力を加えると，分子2面角θが増加するときに，化学置換の効果と逆にバンド幅Wは増加する．このように，物理圧効果と化学置換効果とは，体積の減少という点では似ているが本質的には異なることが明らかになった．更に10.7kbarの物理的圧力下では，衛星反射の観測により他に類例のない圧力誘起の2k(F)CDWを発見した．これはバンド幅の増大と擬1次元的なフェルミ面の形成の双方に起因するものとして理解される．
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=渡邉真史
kn-aut-sei=渡邉
kn-aut-mei=真史
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2002
dt-pub=20020325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=宇宙線空気シャワー中の大広域にわたる相関の研究
kn-title=Study on large-scale correlations in cosmic ray air showers
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=越智信彰
kn-aut-sei=越智
kn-aut-mei=信彰
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1998
dt-pub=19980325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=ブドウにおけるチャノキイロアザミウマの発生生態と防除に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=チャノキイロアザミウマScirtothrips dorsalis Hood (アザミウマ目，アザミウマ科)はブドウの最重要害虫である。本研究では、ブドウにおける本種の発生生態および生態的特性を明らかにし、それをもとにして本種の各種防除手段の有効性を検討した。 以下に主要な結論を要約する。1．ブドウにおけるチャノキイロアザミウマの発生生態　(1)露地圃場における個体群の季節的変動と発生部位　本種成虫の初発生は5月上旬に認められたが、生息密度はわずかであった。その後、6月から成幼虫とも生息密度が増加し、7〜9月に多発して9月下旬に減少した。本種の生息密度はネオ・マスカットがマスカット・ベーリーAより高く、推定生息個体数も多かった。新梢全体における本種の発生はネオ・マスカットでは副梢における発生に影響されたが、マスカット・ベーリーAでは8月下旬までは葉茎における発生に影響され、それ以降は副梢における発生に影響された。また、本種の生息密度はネオ・マスカットでは新梢の先端部および中央部で高かったが、マスカット・べーリーAでは新梢の先端部のみで高かった。分布様式は成幼虫とも個体を単位とした集中分布であった。(2)発生変動に及ぼす有用資源の影響　8〜9月の本種の生息密度はネオ・マスカットがデラウェアより高かった。この原因として、デラウェアでは落葉がネオ・マスカットより早く、8〜9月に始まったことと、8〜9月のネオ・マスカットにおける副梢数がデラウェアより多かったことがあげられた。本種の生息密度はブドウの有用資源の量に影響されることが示された。(3)発生密度調査法の比較検討　洗浄法は必要抽出新梢数が調査可能新梢数より少なく抑えられ、発生密度調査法として直接見取り法より実用性が高いと考えられた。黄色粘着トラップによる本種成虫の誘殺は5〜10月に認められ、7〜9月の誘殺数が多かった。直接見取り法による成虫の生息密度と黄色粘着トラップによる誘殺成虫数、洗浄法による成虫の採集個体数と黄色粘着トラップによる誘殺成虫数との間にはともに有意な正の相関関係が認められ、粘着トラップ法は発生密度調査法として利用が可能と考えられた。また、洗浄法で採集された成虫の雌率は高く、粘着トラップ法では低かったことから、雌成虫は新梢に生息している個体が多く、雄成虫は飛翔活動により移動分散している個体が多いと考えられた。(4)越冬場所と越冬態　本種はブドウの樹皮や落葉、および土壌において主として成虫態で越冬することが示されたが、ガラス室内および露地圃場における越冬密度は極めて低かった。これは落葉樹のブドウでは新梢の枯死や落葉のために11月下旬〜12月上旬に付近の常緑樹へ成虫が移動するためと考えられ、ブドウでは圃場内よりその付近の常緑樹、およびその落葉や周辺の土壌で越冬した成虫、または第一世代成虫が飛来することにより発生が始まると考えられた。(5)寄主間の移動分散　ブドウ圃場に隣接するイヌマキ防風樹のブドウ園場側と道路側に黄色粘着トラップを設置したところ、誘殺成虫数は道路側よりブドウ圃場側で多かった。本種成虫はイヌマキからブドウに向けて寄主間で移動分散していると考えられた。(6)捕食性天敵および寄生性天敵の発生変動　本種の捕食性天敵の候補としてカプリダニ類4種、ハナカメムシ類、ハダニアザミウマの発生を確認できたが、本種の生息密度に及ぼす影響は小さいと考えられた。卵寄生蜂アザミウマタマゴパチは9〜10月に本種卵に対する寄生と羽化を確認したが、寄生率は低く、本種の生息密度に及ぼす影響は小さいと考えられた。(7)発育に及ぼす温度の影響　本種の産卵から孵化までの発育零点は9.5℃、有効積算温度は119.0日度であった。ブドウで飼育した場合の孵化から羽化までの発育零点は7.7℃、有効積算温度は181.8日度であった。以上より、産卵から羽化までの本種の発育零点は8.5℃、有効積算温度は294.1日度であった。(8)年間世代数と発生時期の予察　露地栽培ブドウにおける本種の年間世代数は9〜10世代であると推定された。露地栽培ブドウでは黄色粘着トラップによる最初の成虫の飛来が250日度前後に認められ、550日度前後と850日度前後に2回の成虫のピークが認められた。それぞれ、越冬世代成虫、第一世代成虫および第二世代成虫の発生と考えられた。施設栽培ブドウにおける黄色粘着トラップの誘殺成虫数は4月上旬〜5月中旬より増加し、12〜3月の誘殺はほとんど認められなかった。施設栽培のブドウでは主として施設外からの成虫の飛来侵入により発生が始まると考えられた。2.ブドウにおけるチャノキイロアザミウマの防除　(1)被害解析　露地栽培デラウェアの果房における生息密度と被害との聞には6月中旬〜7月中旬に有意な正の相関関係が認められ、この時期の生息密度の多少が被害に関与することが示唆された。 被害度20に対する果房当たり被害許容密度は6月中旬では0.8個体、6月下旬では2.0個体、7月上旬では3.5個体、7月中旬では4.0個体と推定され、密度は低かった。 また、黄色粘着トラップによる誘殺成虫数と被害との間にも6月中旬〜7月中旬に有意な正の相関関係が認められた。被害度20に対する黄色粘着トラップによるトラップ当たり日当たり被害許容水準は誘殺成虫数が6月中旬では10.1個体、6月下旬では10.0個体、7月上旬では23.0個体、7月中旬では71.8個体と推定された。 ブドウにおいて黄色粘着トラップを設置することによって、防除要否を判断することが可能であると考えられた。 施設栽培ブドウでは本種の被害程度は低く抑えられ、これは落花直後から幼果期に本種が低密度で推移したためと考えられた。(2)殺虫剤散布による化学的防除　露地栽培デラウェアではペルメトリン剤の散布によって新梢では10日間、果房では30日間、幼虫密度の増加が抑制され、落花直後から1か月間に相当する6月中旬〜7月中旬の生息密度を抑制することで被害程度は低く抑えられることが示された。また、露地栽培デラウェアでは本種の防除のため、一般的には5月下旬と6月中旬に殺虫剤を2回散布する必要があると考えられるが、本種の発生が少ない場合には6月中旬に殺虫剤を1回散布することで十分な密度抑制効果と被害防止効果が得られた。黄色粘着トラップによる誘殺成虫数と気象データによる有効積算温度の算出により本種の発生を把握し、ブドウの落花時期を考慮して適期
に防除を行う必要があると考えられた。現在のところ、各種殺虫剤による本種の密度抑制効果と被害防止効果は高く、薬剤抵抗性の発達は認められなかった。(3)新梢管理による耕種的防除　露地栽培ブドウにおいて副梢の切除管理によってブドウの有用資源量を抑制することで、本種の生息密度を低く抑えることができた。この方法はブドウにおける本種の総合的防除を補完する技術のひとつとして有効であると考えられた。(4) フィルム被覆による物理的防除　露地栽培ブドウにおいて酢酸ビニールフィルムを屋根掛け被覆することで、本種の生息密度を低く抑えることができた。この原因として、屋根掛け被覆によって成虫の飛来侵入が抑制されたことと、紫外線カットタイプのフィルムの被覆により成虫の行動が抑制された可能性が考えられた。屋根掛け被覆により被害が軽減される傾向が認められ、この方法はフドウにおける本種の総合的防除を補完する技術のひとつとして有効であると考えられた。
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=柴尾学
kn-aut-sei=柴尾
kn-aut-mei=学
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1995
dt-pub=19950325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Oncogene and Tumor Suppressor Gene Products in Ameloblastoma and Malignant Ameloblastoma : Correlation with Cell Kinetics
kn-title=エナメル上皮腫，悪性エナメル上皮腫における細胞増殖能と癌遺伝子産物，癌抑制遺伝子産物の相関
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=HayashiKatsuhiko
en-aut-sei=Hayashi
en-aut-mei=Katsuhiko
kn-aut-name=林勝彦
kn-aut-sei=林
kn-aut-mei=勝彦
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
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dt-received=
dt-revised=
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dt-pub-year=2003
dt-pub=20030325
dt-online=
en-article=
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en-subject=
kn-subject=
en-title=
kn-title=歯原性腫瘍の形態分化･機能分化とBMP family発現の相関
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=InoueMasahisa
en-aut-sei=Inoue
en-aut-mei=Masahisa
kn-aut-name=井上正久
kn-aut-sei=井上
kn-aut-mei=正久
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
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dt-received=
dt-revised=
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dt-pub-year=2001
dt-pub=20010325
dt-online=
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en-subject=
kn-subject=
en-title=
kn-title=ビスマス系酸化物ガラスの構造､電子状態､ガラス化機構及びその相関について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=渡邊智大
kn-aut-sei=渡邊
kn-aut-mei=智大
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1998
dt-pub=19980930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=音楽呈示における指尖容積微分脈波の波高変化と気分状態の相関関係
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=松浦美晴
kn-aut-sei=松浦
kn-aut-mei=美晴
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
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dt-received=
dt-revised=
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dt-pub-year=1991
dt-pub=19910328
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=マントル深部の相関係の実験的研究: マントルの化学的･熱的構造及び気圏との相互作用
kn-title=EXPERIMENTAL STUDY OF THE PHASE RELATIONS IN THE DEEP MANTLE : THE CHEMICAL AND THERMAL STRUCTURE AND THE INTERACTION WITH THE ATMOSPHERE.
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kn-title=定位脳手術における頭蓋脳相関と Forel-H 野を中心とした脳基底核群の立体的位置関係に関する研究
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en-title=音楽に関係した精神作業中の脳波ならびに循環機能の変化 第1編ピアノ演奏および関連する精神作業中に生じる脳波変化) 第2編音楽活動中の脳波および循環機能の変化) 第3編音楽聴収による生理機能の変動と大学生の音楽学習歴におけるばらつきの相関)
kn-title=第1編　Electroencephalographic　changes　during　piano　playing　and　related　mental　takes　　第2編　Changes　in　the　EEG　and　circulatory　functions　during　musical　tasks　　第3編　Correlation　between　the　variance　in　physiological　function　scaused　by　listening　to　music　and　divergence　in　the　histories　of　musical　traning　of　university　students
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kn-title=高度先端医療技術の導入と都道府県別の虚血性心疾患における致命率の関連性〜死亡/患者比を用いた地域相関分析〜
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kn-title=ラット小腸移植による Graft-Versus-Host Disease (GVHD) と Natural Killer (NK) 細胞活性の相関 特に cutaneous GVHD との関連について
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en-title=脳血流慢性低潅流ラットにおけるコリン作動性神経機能低下と弁別学習障害の相関
kn-title=Relationship between cholinergic dysfunction and discrimination learning disabilities in Wistar rats following chronic cerebral hypoperfusion
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en-title=Microsatellite Instabilityを示す大腸癌におけるE2F4とhMSH3 遺伝子変異の相関
kn-title=Close Correlation between Mutations of E'2F4 and hMSH3 Genes in Colorectal Cancers with Microsatellite Instability
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dt-pub-year=1983
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kn-title=Cephalosporin 系抗生物質の痙攣誘発作用について 第1報 Cephalosporin 系抗生物質の脳室内投与による痙攣誘発作用とその構造 活性相関 第2報 静脈内投与による痙牽誘発作用と抗痙攣薬の抑制作用について
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affil-num=1
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kn-affil=岡山大学
END

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dt-pub-year=1968
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kn-title=家兎唾液腺の水分,塩分ならびに蛋白質分泌の相関性について
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en-aut-name=
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affil-num=1
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END

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dt-pub-year=1990
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kn-title=パーキンソニズムの頭皮上と深部脳波の相関分析
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END

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en-title=再灌流療法成功心筋梗塞症例におけるプロコラーゲン�T C末ペプチド(PICP)およびコラーゲンI C 末テロペプチド(ICTP)の経時的変化:左室容量係数との相関について
kn-title=Time-dependent　changes　of　serum　carboxy-terminal　peptide　of　field name="type"　I　procollagen　and　carboxy-terminal　telopeptide　of　field name="type"　I　collagen　concentrations　in　patients　with　acute　myocardial　infarction　after　successful　reperfusion:correlation　with　left　ventricular　volume　indices
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ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END