start-ver=1.4 cd-journal=joma no-vol=25 cd-vols= no-issue=1 article-no= start-page=1 end-page=5 dt-received= dt-revised= dt-accepted= dt-pub-year=2018 dt-pub=20181227 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Non-calcareous beachrock found in Akagurisaki, Ohi Town, Fukui Prefecture kn-title=福井県おおい町赤礁崎で見出された非石灰質ビーチロック en-subtitle= kn-subtitle= en-abstract= kn-abstract= Beachrock which was formed about 0.5 meter higher than high tide is found in Akagurisaki, Ohi Town, Fukui Prefecture. The outcrops always get wet by spring water. The sediments are composed of well sorted rounded gravels and sands but calcareous shell is not found at all. Intergranular space is occupied by white amorphous cement. Magnesium and silicon rich composition of the cement is obtained by EPMA analysis. There is a conjecture that the magnesium rich cement was precipitated in spite of solution of calcareous shell under saturated state by spring water, because calcium has a higher tendency to ionize than magnesium. en-copyright= kn-copyright= en-aut-name=SuzukiShigeyuki en-aut-sei=Suzuki en-aut-mei=Shigeyuki kn-aut-name=鈴木茂之 kn-aut-sei=鈴木 kn-aut-mei=茂之 aut-affil-num=1 ORCID= en-aut-name=AzumaYoichi en-aut-sei=Azuma en-aut-mei=Yoichi kn-aut-name=東洋一 kn-aut-sei=東 kn-aut-mei=洋一 aut-affil-num=2 ORCID= en-aut-name=DeyamaYasuyo en-aut-sei=Deyama en-aut-mei=Yasuyo kn-aut-name=出山康代 kn-aut-sei=出山 kn-aut-mei=康代 aut-affil-num=3 ORCID= en-aut-name=YukawaHirokazu en-aut-sei=Yukawa en-aut-mei=Hirokazu kn-aut-name=湯川弘一 kn-aut-sei=湯川 kn-aut-mei=弘一 aut-affil-num=4 ORCID= en-aut-name=UsuiMayumi en-aut-sei=Usui en-aut-mei=Mayumi kn-aut-name=臼井まゆみ kn-aut-sei=臼井 kn-aut-mei=まゆみ aut-affil-num=5 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil=岡山大学大学院自然科学研究科 affil-num=2 en-affil=平寺町松岡兼定島 4-1-1 ** kn-affil=福井県立大学恐竜学研究所 affil-num=3 en-affil=平寺町松岡兼定島 4-1-1 ** kn-affil=福井県立大学恐竜学研究所 affil-num=4 en-affil=Fukui Prefectural Dinosaur Museum kn-affil=福井県立恐竜博物館 affil-num=5 en-affil=Fujigakuin-Okayama kn-affil=富士学院 en-keyword=Beachrock kn-keyword=Beachrock en-keyword=Akagurisaki kn-keyword=Akagurisaki en-keyword=non-calcareous cement kn-keyword=non-calcareous cement en-keyword=ionization tendency kn-keyword=ionization tendency END start-ver=1.4 cd-journal=joma no-vol=24 cd-vols= no-issue=1 article-no= start-page=1 end-page=4 dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20171227 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Rounded pebble of metamorphosed iron-formations from conglomerate of the Miocene deposits in Yatakayama, Kibi Plateau, Okayama Prefecture kn-title=岡山県吉備高原弥高山地域に分布する中新統礫岩から変成鉄鉱石礫の発見 en-subtitle= kn-subtitle= en-abstract= kn-abstract= The Kibi Plateau was a part of the Eurasian Continent and separated by the event of opening of Japan Sea. The rounded pebble which is considered to be continental origin was discovered. The pebble is siliceous and attracts magnets. Prepared thin-sections were observed under microscope. Selected minerals were analyzed by EPMA. The rock is composed of recrystallized quartz, magnetite, riebeckite, stilpnomelane and associated with very tiny minerals with very high relief and interference colors. The assemblage suggests that there is a possibility that the rock is a metamorphic rock of iron-formations and derived from continent. en-copyright= kn-copyright= en-aut-name=SuzukiShigeyuki en-aut-sei=Suzuki en-aut-mei=Shigeyuki kn-aut-name=鈴木茂之 kn-aut-sei=鈴木 kn-aut-mei=茂之 aut-affil-num=1 ORCID= en-aut-name=小網晴男 en-aut-sei=小網 en-aut-mei=晴男 kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=臼井まゆみ en-aut-sei=臼井 en-aut-mei=まゆみ kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil=岡山大学大学院自然科学研究科 affil-num=2 en-affil=Okayama Prefectural Okayama Asahi Senior High School kn-affil=岡山県立岡山朝日高等学校 affil-num=3 en-affil=Fujigakuin-Okayama kn-affil=富士学院 en-keyword=Continental origin kn-keyword=Continental origin en-keyword=Miocene conglomerate kn-keyword=Miocene conglomerate en-keyword=rounded pebble kn-keyword=rounded pebble en-keyword=iron-formations kn-keyword=iron-formations en-keyword=Kibi Plateau kn-keyword=Kibi Plateau END start-ver=1.4 cd-journal=joma no-vol=128 cd-vols= no-issue=1 article-no= start-page=21 end-page=25 dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20160401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of mucinous adenocarcinoma of the duodenum and literature review of 16 cases reported in Japan kn-title=原発性十二指腸粘液癌の一例― 本邦報告16例の検討― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　Primary mucinous adenocarcinoma of the duodenum is rare. Here we report a case we recently encountered, and we review 16 cases reported in Japan. An 82-year-old Japanese woman was admitted to our hospital complaining of abdominal pain and heartburn. An endoscopic examination revealed a Type 2 tumor in the descending limb of the duodenum, and endoscopically obtained specimens revealed a poorly differentiated adenocarcinoma. We performed a curative pancreatoduodenectomy with lymph node resection, and the surgical specimen revealed that the duodenum was the primary site of the mucinous adenocarcinoma. The patient is currently alive ＞ 1 year after the operation without any evidence of recurrence. Of the 16 patients reviewed, all patients had advanced tumors those depth were T3-T4. 9 patients had lymph node metastasis and 4 patients had peritoneal dissemination at the time of surgery. Since mucinous adenocarcinoma of the duodenum is often progressive cancer at a diagnosis, which is tend to have a worse prognosis than other histological types. en-copyright= kn-copyright= en-aut-name=HamanoIkumi en-aut-sei=Hamano en-aut-mei=Ikumi kn-aut-name=浜野郁美 kn-aut-sei=浜野 kn-aut-mei=郁美 aut-affil-num=1 ORCID= en-aut-name=MatsumotoYusuke en-aut-sei=Matsumoto en-aut-mei=Yusuke kn-aut-name=松本祐介 kn-aut-sei=松本 kn-aut-mei=祐介 aut-affil-num=2 ORCID= en-aut-name=EndoYoshikatsu en-aut-sei=Endo en-aut-mei=Yoshikatsu kn-aut-name=遠藤芳克 kn-aut-sei=遠藤 kn-aut-mei=芳克 aut-affil-num=3 ORCID= en-aut-name=WatanabeNaoki en-aut-sei=Watanabe en-aut-mei=Naoki kn-aut-name=渡邊直樹 kn-aut-sei=渡邊 kn-aut-mei=直樹 aut-affil-num=4 ORCID= en-aut-name=KaiKyouhei en-aut-sei=Kai en-aut-mei=Kyouhei kn-aut-name=甲斐恭平 kn-aut-sei=甲斐 kn-aut-mei=恭平 aut-affil-num=5 ORCID= en-aut-name=SatoShizou en-aut-sei=Sato en-aut-mei=Shizou kn-aut-name=佐藤四三 kn-aut-sei=佐藤 kn-aut-mei=四三 aut-affil-num=6 ORCID= en-aut-name=WaniYoji en-aut-sei=Wani en-aut-mei=Yoji kn-aut-name=和仁洋治 kn-aut-sei=和仁 kn-aut-mei=洋治 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=姫路赤十字病院　外科 affil-num=2 en-affil= kn-affil=姫路赤十字病院　外科 affil-num=3 en-affil= kn-affil=姫路赤十字病院　外科 affil-num=4 en-affil= kn-affil=姫路赤十字病院　外科 affil-num=5 en-affil= kn-affil=姫路赤十字病院　外科 affil-num=6 en-affil= kn-affil=姫路赤十字病院　外科 affil-num=7 en-affil= kn-affil=姫路赤十字病院　病理診断科 en-keyword=原発性十二指腸癌（primary duodenal cancer） kn-keyword=原発性十二指腸癌（primary duodenal cancer） en-keyword=粘液癌（mucinous carcinoma） kn-keyword=粘液癌（mucinous carcinoma） en-keyword=膵頭十二指腸切除（pancreatoduodenectomy） kn-keyword=膵頭十二指腸切除（pancreatoduodenectomy） END start-ver=1.4 cd-journal=joma no-vol=127 cd-vols= no-issue=3 article-no= start-page=213 end-page=218 dt-received= dt-revised= dt-accepted= dt-pub-year=2015 dt-pub=20151201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case report of giant ectopic pheochromocytoma conversion therapy with radioisotope therapy and chemotherapy followed by curative resection kn-title=術前内照射および化学療法が著効し,根治切除し得た巨大異所性褐色細胞腫の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A 46-year-old man was found to be positive for occult blood at a medical checkup and was revealed to have a 14-cm tumor on the right side of abdominal aorta by a subsequent abdominal CT scan. The endocrinology laboratory data showed elevations in the levels of serum noradrenaline, and ectopic pheochromocytoma was suspected. The tumor was compressing the inferior vena cava and portal vein, the superior mesenteric artery and the pancreas. Since it would be difficult to cure by operation, neoadjuvant therapy was started using radioisotope therapy by I-131 metaiodobenzylguanidine (131I-MIBG) and chemotherapy (CVD therapy ; cyclophosphamide, vincristine, dacarbazine). He was treated with three courses of radioisotope therapy and 16 courses of chemotherapy, which significantly reduced the tumor size. This made radical resection possible ; we were able to avoid the merger excision of great vessels and other organs. On pathological and immunopathological findings, the tumor was diagnosed as ectopic　pheochromocytoma. Regarding the safety and curability of the treatment, neoadjuvant therapy may be useful in treating very large tumors that show invasion of other organs. en-copyright= kn-copyright= en-aut-name=YasuiKazuya en-aut-sei=Yasui en-aut-mei=Kazuya kn-aut-name=安井和也 kn-aut-sei=安井 kn-aut-mei=和也 aut-affil-num=1 ORCID= en-aut-name=UmedaYuzo en-aut-sei=Umeda en-aut-mei=Yuzo kn-aut-name=楳田祐三 kn-aut-sei=楳田 kn-aut-mei=祐三 aut-affil-num=2 ORCID= en-aut-name=KumanoKenjiro en-aut-sei=Kumano en-aut-mei=Kenjiro kn-aut-name=熊野健二郎 kn-aut-sei=熊野 kn-aut-mei=健二郎 aut-affil-num=3 ORCID= en-aut-name=TabataMasahiro en-aut-sei=Tabata en-aut-mei=Masahiro kn-aut-name=田端雅弘 kn-aut-sei=田端 kn-aut-mei=雅弘 aut-affil-num=4 ORCID= en-aut-name=OtsukaFumio en-aut-sei=Otsuka en-aut-mei=Fumio kn-aut-name=大塚文男 kn-aut-sei=大塚 kn-aut-mei=文男 aut-affil-num=5 ORCID= en-aut-name=YagiTakahito en-aut-sei=Yagi en-aut-mei=Takahito kn-aut-name=八木孝仁 kn-aut-sei=八木 kn-aut-mei=孝仁 aut-affil-num=6 ORCID= en-aut-name=FujiwaraToshiyoshi en-aut-sei=Fujiwara en-aut-mei=Toshiyoshi kn-aut-name=藤原俊義 kn-aut-sei=藤原 kn-aut-mei=俊義 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 affil-num=6 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 affil-num=7 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 en-keyword=異所性褐色細胞腫（ectopic pheochromocytoma） kn-keyword=異所性褐色細胞腫（ectopic pheochromocytoma） en-keyword=化学療法（chemo therapy） kn-keyword=化学療法（chemo therapy） en-keyword=131I-MIBG kn-keyword=131I-MIBG END start-ver=1.4 cd-journal=joma no-vol=126 cd-vols= no-issue=3 article-no= start-page=209 end-page=215 dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=20141201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Hospital and clinic cooperation for the treatment of rheumatoid arthritis in Okayama Prefecture, Japan kn-title=岡山県下のクリニック・診療所におけるリウマチ診療・病診連携の実態に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Objective: To survey the current status and problems of cooperation between clinics and hospitals in Okayama Prefecture, Japan for the treatment of rheumatoid arthritis (RA). 　Methods: We distributed a questionnaire to 300 of the 983 Okayama Prefecture clinics that had either an internal medicine or orthopedic surgery department, from December 2013 to February 2014. The questionnaire covered practice pattern for RA treatment in clinics, current status of the hospital and clinic cooperation, and acceptance of the biologic therapy. 　Results: One hundred clinics responded to the questionnaire. Seventy percent of the clinics reported making referrals to rheumatologists before the initiation of RA treatment, and half of the other 30% of the clinics administered methotrexate as the first-line treatment for RA by their own decision. Sixty-six clinics cooperated with flagship hospitals, conducting medical and laboratory examinations, providing prescriptions, and treating common diseases of patients. These clinics expected the cooperating rheumatologists to follow-up patients every 3 to 6 months and to make the diagnosis, make decisions regarding RA treatment changes, and perform surgery. Seventy-one percent of the clinics responded that cooperation with a hospital is possible even for patients who are administered biologics. As reasons for no cooperation with the flagship hospitals, clinics noted the lack of information about rheumatologists in the area and recent trends in the management of RA. 　Conclusion: The current study reported, for the first time, the actual conditions of management of RA in clinics, as well as future problems of hospital and clinic cooperation in Okayama Prefecture. en-copyright= kn-copyright= en-aut-name=SadaKen-ei en-aut-sei=Sada en-aut-mei=Ken-ei kn-aut-name=佐田憲映 kn-aut-sei=佐田 kn-aut-mei=憲映 aut-affil-num=1 ORCID= en-aut-name=NishidaKeiichiro en-aut-sei=Nishida en-aut-mei=Keiichiro kn-aut-name=西田圭一郎 kn-aut-sei=西田 kn-aut-mei=圭一郎 aut-affil-num=2 ORCID= en-aut-name=YamanakaTakao en-aut-sei=Yamanaka en-aut-mei=Takao kn-aut-name=山中隆夫 kn-aut-sei=山中 kn-aut-mei=隆夫 aut-affil-num=3 ORCID= en-aut-name=MisakiKenta en-aut-sei=Misaki en-aut-mei=Kenta kn-aut-name=三崎健太 kn-aut-sei=三崎 kn-aut-mei=健太 aut-affil-num=4 ORCID= en-aut-name=WakabayashiHiroshi en-aut-sei=Wakabayashi en-aut-mei=Hiroshi kn-aut-name=若林宏 kn-aut-sei=若林 kn-aut-mei=宏 aut-affil-num=5 ORCID= en-aut-name=ShinodaJunko en-aut-sei=Shinoda en-aut-mei=Junko kn-aut-name=篠田潤子 kn-aut-sei=篠田 kn-aut-mei=潤子 aut-affil-num=6 ORCID= en-aut-name=TakagiToru en-aut-sei=Takagi en-aut-mei=Toru kn-aut-name=木徹 kn-aut-sei=木 kn-aut-mei=徹 aut-affil-num=7 ORCID= en-aut-name=YanoRyusuke en-aut-sei=Yano en-aut-mei=Ryusuke kn-aut-name=矢野隆介 kn-aut-sei=矢野 kn-aut-mei=隆介 aut-affil-num=8 ORCID= en-aut-name=NakamuraAkihiko en-aut-sei=Nakamura en-aut-mei=Akihiko kn-aut-name=中村明彦 kn-aut-sei=中村 kn-aut-mei=明彦 aut-affil-num=9 ORCID= en-aut-name=NanbaYoshifumi en-aut-sei=Nanba en-aut-mei=Yoshifumi kn-aut-name=難波良文 kn-aut-sei=難波 kn-aut-mei=良文 aut-affil-num=10 ORCID= en-aut-name=MoritaYoshitaka en-aut-sei=Morita en-aut-mei=Yoshitaka kn-aut-name=守田吉孝 kn-aut-sei=守田 kn-aut-mei=吉孝 aut-affil-num=11 ORCID= en-aut-name=KoyamaYoshinobu en-aut-sei=Koyama en-aut-mei=Yoshinobu kn-aut-name=小山芳伸 kn-aut-sei=小山 kn-aut-mei=芳伸 aut-affil-num=12 ORCID= en-aut-name=YamamotoKeiji en-aut-sei=Yamamoto en-aut-mei=Keiji kn-aut-name=山本惠嗣 kn-aut-sei=山本 kn-aut-mei=惠嗣 aut-affil-num=13 ORCID= en-aut-name=EzawaKazuhiko en-aut-sei=Ezawa en-aut-mei=Kazuhiko kn-aut-name=江澤和彦 kn-aut-sei=江澤 kn-aut-mei=和彦 aut-affil-num=14 ORCID= en-aut-name=OtaYusuke en-aut-sei=Ota en-aut-mei=Yusuke kn-aut-name=太田裕介 kn-aut-sei=太田 kn-aut-mei=裕介 aut-affil-num=15 ORCID= en-aut-name=YoshiharaYoshiki en-aut-sei=Yoshihara en-aut-mei=Yoshiki kn-aut-name=吉原由樹 kn-aut-sei=吉原 kn-aut-mei=由樹 aut-affil-num=16 ORCID= en-aut-name=MiyoshiShinya en-aut-sei=Miyoshi en-aut-mei=Shinya kn-aut-name=三好信也 kn-aut-sei=三好 kn-aut-mei=信也 aut-affil-num=17 ORCID= en-aut-name=NatsumedaMasamitsu en-aut-sei=Natsumeda en-aut-mei=Masamitsu kn-aut-name=棗田将光 kn-aut-sei=棗田 kn-aut-mei=将光 aut-affil-num=18 ORCID= en-aut-name=UsuiMasaaki en-aut-sei=Usui en-aut-mei=Masaaki kn-aut-name=臼井正明 kn-aut-sei=臼井 kn-aut-mei=正明 aut-affil-num=19 ORCID= en-aut-name=YoshinagaYasuhiko en-aut-sei=Yoshinaga en-aut-mei=Yasuhiko kn-aut-name=吉永泰彦 kn-aut-sei=吉永 kn-aut-mei=泰彦 aut-affil-num=20 ORCID= en-aut-name=HayashiTakashi en-aut-sei=Hayashi en-aut-mei=Takashi kn-aut-name=林充 kn-aut-sei=林 kn-aut-mei=充 aut-affil-num=21 ORCID= en-aut-name=YamamuraMasahiro en-aut-sei=Yamamura en-aut-mei=Masahiro kn-aut-name=山村昌弘 kn-aut-sei=山村 kn-aut-mei=昌弘 aut-affil-num=22 ORCID= en-aut-name=HashizumeHiroyuki en-aut-sei=Hashizume en-aut-mei=Hiroyuki kn-aut-name=橋詰博行 kn-aut-sei=橋詰 kn-aut-mei=博行 aut-affil-num=23 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　腎・免疫・内分泌代謝内科学 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　人体構成学 affil-num=3 en-affil= kn-affil=南岡山医療センター　リウマチ科 affil-num=4 en-affil= kn-affil=倉敷中央病院　内分泌代謝・リウマチ内科 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　腎・免疫・内分泌代謝内科学 affil-num=6 en-affil= kn-affil=岡山労災病院　整形外科 affil-num=7 en-affil= kn-affil=岡山赤十字病院　整形外科 affil-num=8 en-affil= kn-affil=矢野内科医院 affil-num=9 en-affil= kn-affil=おさふねクリニック affil-num=10 en-affil= kn-affil=川崎医科大学附属病院　整形外科 affil-num=11 en-affil= kn-affil=川崎医科大学附属病院　リウマチ・膠原病科 affil-num=12 en-affil= kn-affil=岡山赤十字病院　膠原病リウマチ内科 affil-num=13 en-affil= kn-affil=山本整形外科医院 affil-num=14 en-affil= kn-affil=倉敷スイートホスピタル　内科 affil-num=15 en-affil= kn-affil=香川労災病院　整形外科 affil-num=16 en-affil= kn-affil=倉敷成人病センター　整形外科 affil-num=17 en-affil= kn-affil=倉敷成人病センター　整形外科 affil-num=18 en-affil= kn-affil=倉敷スイートホスピタル　内科 affil-num=19 en-affil= kn-affil=岡山市民病院　整形外科 affil-num=20 en-affil= kn-affil=倉敷成人病センター　リウマチ膠原病内科 affil-num=21 en-affil= kn-affil=佐用中央病院　整形外科 affil-num=22 en-affil= kn-affil=岡山済生会総合病院　内科 affil-num=23 en-affil= kn-affil=笠岡第一病院　整形外科 en-keyword=病診連携（hospital and clinic cooperation） kn-keyword=病診連携（hospital and clinic cooperation） en-keyword=関節リウマチ（rheumatoid arthritis） kn-keyword=関節リウマチ（rheumatoid arthritis） en-keyword=生物学的製剤（biologics） kn-keyword=生物学的製剤（biologics） en-keyword=メトトレキサート（methotrexate） kn-keyword=メトトレキサート（methotrexate） END start-ver=1.4 cd-journal=joma no-vol=67 cd-vols= no-issue=3 article-no= start-page=135 end-page=143 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=201306 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Somatosensory and Visual Deprivation Each Decrease the Density of Parvalbumin Neurons and Their Synapse Terminals in the Prefrontal Cortex and Hippocampus of Mice en-subtitle= kn-subtitle= en-abstract= kn-abstract=In the phenomenon known as cross-modal plasticity, the loss of one sensory system is followed by improved functioning of other intact sensory systems. MRI and functional MRI studies suggested a role of the prefrontal cortex and the temporal lobe in cross-modal plasticity. We used a mouse model to examine the effects of sensory deprivation achieved by whisker trimming and visual deprivation achieved by dark rearing in neonatal mice on the appearance of parvalbumin (PV) neurons and the formation of glutamic acid decarboxylase 67 (GAD67)-positive puncta around pyramidal neurons in the prefrontal cortex and hippocampus. Whisker trimming, but not dark rearing, decreased the density of PV neurons in the hippocampus at postnatal day 28 (P28). In the prefrontal cortex, whisker trimming and dark rearing decreased the density of PV neurons in layer 5/6 (L5/6) at P28 and in L2/3 at P56, respectively, whereas dark rearing increased the density of PV neurons in L5/6 at P56. Whisker trimming decreased the density of GAD67-positive puncta in CA1 of the hippocampus at both P28 and P56 and in L5/6 of the prefrontal cortex at P28. Dark rearing decreased the density of GAD67-positive puncta in CA1 of the hippocampus and in both L2/3 and L5/6 of the prefrontal cortex at P28, and in L2/3 of the prefrontal cortex at P56. These results demonstrate that somatosensory or visual deprivation causes changes in the PV-interneuronal network in the mouse prefrontal cortex and hippocampus. The results also suggest that the alteration of the PV-interneuronal network, especially in the prefrontal cortex, may contribute to cross-modal plasticity. en-copyright= kn-copyright= en-aut-name=UenoHiroshi en-aut-sei=Ueno en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShoshiChikafumi en-aut-sei=Shoshi en-aut-mei=Chikafumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SuemitsuShunsuke en-aut-sei=Suemitsu en-aut-mei=Shunsuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=UsuiShinichi en-aut-sei=Usui en-aut-mei=Shinichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SujiuraHiroko en-aut-sei=Sujiura en-aut-mei=Hiroko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=OkamotoMotoi en-aut-sei=Okamoto en-aut-mei=Motoi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University affil-num=2 en-affil= kn-affil=Department of Medical Technology, Kawasaki College of Allied Health Professions affil-num=3 en-affil= kn-affil=Department of Psychiatry, Kawasaki Medical University affil-num=4 en-affil= kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University affil-num=5 en-affil= kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University affil-num=6 en-affil= kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University en-keyword=sensory deprivation kn-keyword=sensory deprivation en-keyword=parvalbumin kn-keyword=parvalbumin en-keyword=glutamate decarboxylase (GAD67) kn-keyword=glutamate decarboxylase (GAD67) en-keyword=prefrontal cortex kn-keyword=prefrontal cortex en-keyword=hippocampus kn-keyword=hippocampus END start-ver=1.4 cd-journal=joma no-vol=66 cd-vols= no-issue=2 article-no= start-page=143 end-page=154 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=201204 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Attenuated Sensory Deprivation-induced Changes of Parvalbumin Neuron Density in the Barrel Cortex of FcγRllB-deficient Mice en-subtitle= kn-subtitle= en-abstract= kn-abstract=Recent studies have demonstrated the important role of immune molecules in the development of neuronal circuitry and synaptic plasticity. We have detected the presence of FcγRllB protein in parvalbumin- containing inhibitory interneurons (PV neurons). In the present study, we examined the appearance of PV neurons in the barrel cortex and the effect of sensory deprivation in FcγRllB-deficient mice (FcγRllB-/-) and wild-type mice. There was no substantial difference in the appearance of PV neurons in the developing barrel cortex between FcγRllB-/- and wild-type mice. Sensory deprivation from immediately after birth (P0) or P7 to P12-P14 induced an increase in PV neurons. In contrast, sensory deprivation from P7 or P14 to P28, but not from P21 to P28, decreased PV neurons in wild-type mice. However, sensory deprivation from P0 or P7 to P12-P14 did not increase PV neurons and sensory deprivation from P7 or P14 to P28 did not decrease or only modestly decreased PV neurons in FcγRllB-/- mice. The results indicate that expression of PV is regulated by sensory experience and the second and third postnatal weeks are a sensitive period for sensory deprivation, and suggest that FcγRllB contributes to sensory experience-regulated expression of PV. en-copyright= kn-copyright= en-aut-name=WatanabeMakiko en-aut-sei=Watanabe en-aut-mei=Makiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=UenoHiroshi en-aut-sei=Ueno en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SuemitsuShunsuke en-aut-sei=Suemitsu en-aut-mei=Shunsuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YokobayashiEriko en-aut-sei=Yokobayashi en-aut-mei=Eriko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MatsumotoYosuke en-aut-sei=Matsumoto en-aut-mei=Yosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=UsuiShinichi en-aut-sei=Usui en-aut-mei=Shinichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=SujiuraHiroko en-aut-sei=Sujiura en-aut-mei=Hiroko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=OkamotoMotoi en-aut-sei=Okamoto en-aut-mei=Motoi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University affil-num=2 en-affil= kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University affil-num=3 en-affil= kn-affil=Koyodai Hospital affil-num=4 en-affil= kn-affil=Department of Psychiatry, Kawasaki Medical University affil-num=5 en-affil= kn-affil=Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=6 en-affil= kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University affil-num=7 en-affil= kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University affil-num=8 en-affil= kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University en-keyword=parvalbumin kn-keyword=parvalbumin en-keyword=fast-spiking interneurons kn-keyword=fast-spiking interneurons en-keyword=FcγRllB kn-keyword=FcγRllB en-keyword=barrel cortex kn-keyword=barrel cortex en-keyword=sensory deprivation kn-keyword=sensory deprivation END start-ver=1.4 cd-journal=joma no-vol=41 cd-vols= no-issue=3 article-no= start-page=134 end-page=139 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=200802 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Association of elevated plasma B-type natriuretic peptide levels with paroxysmal atrial fibrillation in patients with nonobstructive hypertrophic cardiomyopathy en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Objectives: To investigate the relationship between the plasma B-type natriuretic peptide (BNP) level and the occurrence of atrial fibrillation (AF) in nonobstructive hypertrophic cardiomyopathy (HCM) patients.
Methods: Patients (n=97) were classified into chronic AF (CAF; n=14), paroxysmal AF (PAF; n=18) and normal sinus rhythm (NSR; n=65) groups. The plasma BNP values were analyzed with logarithmic transformation.
Results: The PAF group showed significantly higher plasma BNP levels than the NSR group [mean (range; -1 SD and +1 SD); 248.3 (143.5, 429.5) vs. 78.2 (27.9, 218.8 ng/L), p<0.0001]. The CAF group also showed significantly higher plasma BNP levels than the NSR group [291.1 (161.4, 524.8 ng/L), p<0.0001]. Multivariate analysis with other clinical factors selected association of PAF as one of the factors that increased the plasma BNP level.
Conclusions: The present study indicated that plasma BNP level is clinically useful for identification of nonobstructive HCM patients who have a risk of PAF.

en-copyright= kn-copyright= en-aut-name=MatsuuraHiroko en-aut-sei=Matsuura en-aut-mei=Hiroko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MurakamiTakashi en-aut-sei=Murakami en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HinaKazuyoshi en-aut-sei=Hina en-aut-mei=Kazuyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamamotoKeizo en-aut-sei=Yamamoto en-aut-mei=Keizo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KawamuraHiroshi en-aut-sei=Kawamura en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SogoTaiji en-aut-sei=Sogo en-aut-mei=Taiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=ShinohataRyoko en-aut-sei=Shinohata en-aut-mei=Ryoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=UsuiShinichi en-aut-sei=Usui en-aut-mei=Shinichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=NinomiyaYoshifumi en-aut-sei=Ninomiya en-aut-mei=Yoshifumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=KusachiShozo en-aut-sei=Kusachi en-aut-mei=Shozo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=Department of Medicine and Medical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=2 en-affil= kn-affil=Department of Cardiology, Cardiovascular Center, Sakakibara Hospital affil-num=3 en-affil= kn-affil=Department of Cardiology, Cardiovascular Center, Sakakibara Hospital affil-num=4 en-affil= kn-affil=Department of Cardiology, Cardiovascular Center, Sakakibara Hospital affil-num=5 en-affil= kn-affil=Department of Cardiology, Cardiovascular Center, Sakakibara Hospital affil-num=6 en-affil= kn-affil=Department of Cardiovascular Medicine, Takamatsu Red Cross Hospital affil-num=7 en-affil= kn-affil=Department of Medical Technology, Okayama University Graduate School of Health Sciences affil-num=8 en-affil= kn-affil=Department of Medical Technology, Okayama University Graduate School of Health Sciences affil-num=9 en-affil= kn-affil=Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=10 en-affil= kn-affil=Department of Medical Technology, Okayama University Graduate School of Health Sciences en-keyword=clinical study kn-keyword=clinical study en-keyword=cardiomyopathy kn-keyword=cardiomyopathy en-keyword=tachyarrhythmia kn-keyword=tachyarrhythmia en-keyword=enzyme immunoassay kn-keyword=enzyme immunoassay en-keyword=peptide kn-keyword=peptide en-keyword=sensitivity and specificity kn-keyword=sensitivity and specificity END start-ver=1.4 cd-journal=joma no-vol=97 cd-vols= no-issue=9-10 article-no= start-page=889 end-page=912 dt-received= dt-revised= dt-accepted= dt-pub-year=1985 dt-pub=19851030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A scanning electron microscopic study of microcirculation of rabbit and human lymph nodes kn-title=家兎およびヒトリンパ節の微細血管構築の走査電子顕微鏡的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Corrosion casts of rabbit and human lymph nodes were observed by SEM. Casts showed a broad bean appearance. On the outer surface of casts, the afferent and efferent vessels and the vessels of the capsule were seen. Cross-sectioned surfaces of the casts showed a marked difference between the architecture of the cortex and the medulla. The casts of primary nodules appeared as small roundish capillary networks. The casts of secondary nodules formed spheres, inside of which there were poor capillaries. Secondary nodules showed many transitions. Pseudo-nodules appeared as egg-like, large capillary networks and included secondary nodules. The capillaries in diffuse lymphoid tissue anastomosed with the PCV. The PCV, which ran deeply into the cortex, anastomosed with the veins of the medulla in the cortico-medullary junction. The capillaries of medulla anastomosed directly with the veins of the medulla. Basically, the elements and arrangements of the vascular casts of the rabbit lymph node were similar to those of the human lymph node. en-copyright= kn-copyright= en-aut-name=UsuiTakashi en-aut-sei=Usui en-aut-mei=Takashi kn-aut-name=臼井隆 kn-aut-sei=臼井 kn-aut-mei=隆 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=高知医科大学第一外科教室 END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=1 article-no= start-page=9 end-page=14 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20041215 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The effect of Coicis semen and Rhizopus oligosporus-fermented Coicis semen (tempeh) on serum cholesterol in the rat kn-title=はとむぎ,はとむぎテンペのラットコレステロール代謝改善作用に関する研究 en-subtitle= kn-subtitle= en-abstract=The effect of Coicis semen and Rhizopus oligosporus-fermented Coicis semen (tempeh) on serum cholesterol fractions was examined in the rat. Twelve-week-old male Sprague-Dawley rats were received commercial MF meal (control group), Coicis semen-containing MF meal (Coicis semen group), or tempeh-containing MF meal (tempeh group). Cholesterol fractions were analyzed by high performance liquid chromatography at the start of experiment, and 2, 6, 18 weeks later. No difference was found in body weight nor total cholesterol among the three groups. LDL cholesterol was significantly lowered in the tempeh group at 2, 6, 18 weeks. LDL cholesterol/HDL cholesterol ratio also decreased at 2 and 18 weeks. In the both Coicis semen- and tempeh-fooded groups, LDL cholesterol and LDL cholesterol/HDL cholesterol ratio were lower than the control group although they were not statistically significant. No difference was found in HDL cholesterol among the three groups. The results suggest that tempeh may have a favorable effect on cholesterol metabolism. kn-abstract=はとむぎ(Coicis semen)をテンペ菌(Rhizopus oligosporus)で発酵したはとむぎテンペ(テンペ)の血清コレステロール代謝に対する作用を検討した｡生後12週齢のSprague-Dawley系雄ラットに市販固形飼料(コントロール群),はとむぎ混合飼料(はとむぎ群),テンペ混合飼料(テンペ群)を投与し,2,6,18週間後に高速液体クロマトグラフィー法で血清コレステロールを測定した｡体重増加,総コレステロールはいずれの時点でも3群間に差がなかったが,テンペ群では投与前と比較して2,6,18週間後にLDLコレステロールが有意に低下し,LDLコレステロール/HDLコレステロール比も2,18週間後に有意に低下した｡テンペ群はコントロール群と比較してもLDLコレステロールとLDLコレステロール/HDLコレステロール比が低く,はとむぎ群でも低い傾向がみられたが,有意差はなかった｡以上から,テンペがコレステロール代謝改善作用をもつことが示唆された｡ en-copyright= kn-copyright= en-aut-name=OkamotoMotoi en-aut-sei=Okamoto en-aut-mei=Motoi kn-aut-name=岡本基 kn-aut-sei=岡本 kn-aut-mei=基 aut-affil-num=1 ORCID= en-aut-name=UsuiShinichi en-aut-sei=Usui en-aut-mei=Shinichi kn-aut-name=臼井真一 kn-aut-sei=臼井 kn-aut-mei=真一 aut-affil-num=2 ORCID= en-aut-name=OkazakiMitsuyo en-aut-sei=Okazaki en-aut-mei=Mitsuyo kn-aut-name=岡崎三代 kn-aut-sei=岡崎 kn-aut-mei=三代 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科検査技術科学専攻 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科検査技術科学専攻 affil-num=3 en-affil= kn-affil=東京医科歯科大学教養部 en-keyword=はとむぎ (Coicis semen) kn-keyword=はとむぎ (Coicis semen) en-keyword=はとむぎテンペ (Rhizopus oligosporus, tempeh) kn-keyword=はとむぎテンペ (Rhizopus oligosporus, tempeh) en-keyword=コレステロール (cholesterol) kn-keyword=コレステロール (cholesterol) en-keyword=ラット (rat) kn-keyword=ラット (rat) END start-ver=1.4 cd-journal=joma no-vol=121 cd-vols= no-issue=2 article-no= start-page=123 end-page=125 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20090803 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=田野病院 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=臼井隆 kn-aut-sei=臼井 kn-aut-mei=隆 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=3-4 article-no= start-page=297 end-page=310 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical and histological studies on steroid-induced avascular necrosis of the femoral head, especially in ststemic lupus erythematosus kn-title=ステロイド性大腿骨頭壊死症の病態に関する研究―全身性エリテマトーデス(SLE)を中心に― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Clinical and radiological studies were performed on avascular necrosis of the femoral head (ANF) in 220 hips 140 patients including 51 hips of 28 patients with systemic lupus erythe-matosus (SLE group). Sixty-nine hips of 41 patients wee treated with corticosteroid adminis-tration (S group) and 100 hips of 71 patients without corticosteroid administration (Non-S group). All patients with SLE were treated with corticosteroid adminstration. Thirty-one femoral heads (11 heads of SLE group, 9 heads of S group and 11 heads of Non-S group) were resected at operations nad studied histologically. Seventy-seven hips at an early stage showed that collapse of the femoral heads occurred in 80% without 3 years and no differences were found among these group. In the SLE group, bilateral involvement, multiple bone necrosis and predilection for young females were apparent. Collapse of the femoral head and subcapital fractures were more frequently seen in the SLE group. Histologically, almost all heads even in the SLE group showed repair process such as enchondral ossification and appositional bone formation, while the heads with subcapital fracture showed no such no such changes. en-copyright= kn-copyright= en-aut-name=UsuiMasaaki en-aut-sei=Usui en-aut-mei=Masaaki kn-aut-name=臼井正明 kn-aut-sei=臼井 kn-aut-mei=正明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部整形外科学教室 en-keyword=大腿骨頭壊死症 kn-keyword=大腿骨頭壊死症 en-keyword=全身性エリテマトーデス(SLE) kn-keyword=全身性エリテマトーデス(SLE) en-keyword=病態 kn-keyword=病態 END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=3-4 article-no= start-page=211 end-page=221 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=1994 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Phagocytic function and production of colony-stimulating factor of peripheral mononuclear cells in the elderly kn-title=高齢者における貪食細胞機能並びに末梢単核球コロニー刺激因子産生能に検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Elderly individuals have an increased susceptibility to infections. To evaluate one of the possible causes of increased susceptibility to infections in the elderly, peripheral neutrophil and monocyte counts, neutrophil and monocyte chemiluminescence (ChL), macrophage precursor test and production of colony-stimulating factor (CSF) of peripheral mononuclear cells (PMNCs) were examined. The neutrophil and monocyte counts in the peripheral blood were not different between the elderly (≧70 years old) and the younger (<70years old) groups. In the neutrophil ChL assay, the base lines, peak levels and peak times were not different between the elderly and the younger groups. In the monocyte ChL assay, the peak level in the elderly group was significantly lower than that in the younger group (p<0.05). The values in a macrophage precursor test in the eldely group were signicantly lower than those in the younger group (P<0.05). CSF production of PMNCs in the eldely was significantly lower than that in the younger group(P<0.05). These findings indicated that the impaired intracel-lular bactericidal activity and maturation ability of monocytes and impaired CSF production of PMNCs were possible causes of increased susceptibility to infections in the elderly. en-copyright= kn-copyright= en-aut-name=OsadaKen en-aut-sei=Osada en-aut-mei=Ken kn-aut-name=長田建 kn-aut-sei=長田 kn-aut-mei=建 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=the elderly kn-keyword=the elderly en-keyword=mononuclear cells kn-keyword=mononuclear cells en-keyword=chemiluminescence kn-keyword=chemiluminescence en-keyword=macrophage precursor test kn-keyword=macrophage precursor test en-keyword=CSF production kn-keyword=CSF production END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=7-8 article-no= start-page=673 end-page=680 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=199308 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental studies on nicaraven as a radioprotector : Survival ratio of mice, spleen colony formation, blood picture and lipid peroxidation kn-title=ニカラベンの放射線防護剤としての有用性の検討―マウス生存率，脾コロニー，末梢血液像，脂質過酸化について― en-subtitle= kn-subtitle= en-abstract= kn-abstract=The degree of radiation protection from Nicaraven after whole-body irradiation was investigated in C3H mice. Nicaraven is a free radical scavenging agent, which was shown to improve brain edema and blood flow. Nicaraven was injected intraperitoneally in mice before and/or after whole-body irradiation with 640cGy or 740cGy using Toshiba Lineac LMR-4C (4MV, 6.45×10(-2)C/s/min). The 30 day survival ratio was improved significantly by Nicaraven (P≦0.02). Endogenous spleen colony formation was investigated after 640cGy. The agent was injected before (pre), after (post) or before and after irradiation (pre-post), and compared with the untreated group (control). Nine days after irradiation, the mean colony formation was 2.00 (pre), 3.09 (post), 4.31 (pre-post) and 1.47 (control). The differences between pre and post (p≦0.01), between pre-post and control (p≦0.01) and between post and control (p≦0.05) were significant. Nicaraven induced recovery of leukocyte and lymphocyte counts after irradiation, but not that of erythrocytes. The effect of the agent on mice liver mitochondrial lipid peroxidation was also investigated. The lag time was not shortened, but reduction of the TBA value was observed. Nicaraven was not only recognized as a radioprotector, but its ability to promote recovery from the damage caused by irradiation was also suggested. en-copyright= kn-copyright= en-aut-name=MoriYasutane en-aut-sei=Mori en-aut-mei=Yasutane kn-aut-name=森泰胤 kn-aut-sei=森 kn-aut-mei=泰胤 aut-affil-num=1 ORCID= en-aut-name=TakashimaHitoshi en-aut-sei=Takashima en-aut-mei=Hitoshi kn-aut-name=高島均 kn-aut-sei=高島 kn-aut-mei=均 aut-affil-num=2 ORCID= en-aut-name=SeoHiroyuki en-aut-sei=Seo en-aut-mei=Hiroyuki kn-aut-name=瀬尾裕之 kn-aut-sei=瀬尾 kn-aut-mei=裕之 aut-affil-num=3 ORCID= en-aut-name=OhkawaMotoomi en-aut-sei=Ohkawa en-aut-mei=Motoomi kn-aut-name=大川元臣 kn-aut-sei=大川 kn-aut-mei=元臣 aut-affil-num=4 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田邉正忠 kn-aut-sei=田邉 kn-aut-mei=正忠 aut-affil-num=5 ORCID= en-aut-name=YamamotoGoki en-aut-sei=Yamamoto en-aut-mei=Goki kn-aut-name=山本剛禧 kn-aut-sei=山本 kn-aut-mei=剛禧 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=香川医科大学放射線医学教室 affil-num=2 en-affil= kn-affil=香川医科大学放射線医学教室 affil-num=3 en-affil= kn-affil=香川医科大学放射線医学教室 affil-num=4 en-affil= kn-affil=香川医科大学放射線医学教室 affil-num=5 en-affil= kn-affil=香川医科大学放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 en-keyword=Radioprotector kn-keyword=Radioprotector en-keyword=Nicaraven kn-keyword=Nicaraven en-keyword=Radical scavenger kn-keyword=Radical scavenger en-keyword=Spleen colony kn-keyword=Spleen colony en-keyword=Lipid peroxidation kn-keyword=Lipid peroxidation END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=7-8 article-no= start-page=751 end-page=756 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=199408 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case report of esophageal cyst kn-title=食道?腫の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Esophageal cyst is a relatively rare disease and about 91 cases have been reported in Japan. We report a new case of esophageal cyst. Tha patient was a 36-year-old male who complained of nausea and vomiting. We performed esophagography, endoscopy, endoxcopic echography, CT and MRI and found a cystic lesion in the lower esophagus. We made the diagnosis of an esophageal cyst and performed operation. The tumor was in the esophageal muscle but did not have a commissure to the esophageal lumen. We extirpated it with esophageal muscle and repaired the muscle defect with diaphragma. This tumor, 7.5×5.0cm in size, was a monolocular cyst and contained brown muddy material. Microscopic findings revealed a ciliated columnar epithelium and squamous epithelium in the cyst wall but cartilage was not found. The cyst was covered with double smooth muscle layers. It was difficult to differentiate an esophageal cyst from a paraesophageal bronchogenic cyst but these histological findings suggested that this cyst was an esophageal cyst. en-copyright= kn-copyright= en-aut-name=IshiiYasunori en-aut-sei=Ishii en-aut-mei=Yasunori kn-aut-name=石井泰則 kn-aut-sei=石井 kn-aut-mei=泰則 aut-affil-num=1 ORCID= en-aut-name=InoueFumiyuki en-aut-sei=Inoue en-aut-mei=Fumiyuki kn-aut-name=井上文之 kn-aut-sei=井上 kn-aut-mei=文之 aut-affil-num=2 ORCID= en-aut-name=BanHidetoshi en-aut-sei=Ban en-aut-mei=Hidetoshi kn-aut-name=伴秀利 kn-aut-sei=伴 kn-aut-mei=秀利 aut-affil-num=3 ORCID= en-aut-name=KamikawaYasuaki en-aut-sei=Kamikawa en-aut-mei=Yasuaki kn-aut-name=上川康明 kn-aut-sei=上川 kn-aut-mei=康明 aut-affil-num=4 ORCID= en-aut-name=OritaKunzo en-aut-sei=Orita en-aut-mei=Kunzo kn-aut-name=折田薫三 kn-aut-sei=折田 kn-aut-mei=薫三 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第一外科学教室 en-keyword=食道?腫 kn-keyword=食道?腫 en-keyword=esophageal cyst kn-keyword=esophageal cyst en-keyword=気管支食道?腫 kn-keyword=気管支食道?腫 en-keyword=bronchial-esophageal cyst kn-keyword=bronchial-esophageal cyst en-keyword=foregut cyst kn-keyword=foregut cyst END start-ver=1.4 cd-journal=joma no-vol=1 cd-vols= no-issue=1 article-no= start-page=137 end-page=152 dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=2003 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=漂流民の自他認識：神力丸バタン漂流事件を素材に en-subtitle= kn-subtitle= en-abstract= kn-abstract=最近の漂流民研究は、近世人の自他認識を考える上で貴重な成果を積み上げてきているのだが、他方では、漂流民研究が持つ根本的な問題も自覚されるようになっている。それは、漂流記の歴史史料としての問題性である。つまり、一般に漂流記録は、帰国後に漂流民を取り調べた役人や談話の聞き手が記したもので、それがどこまで漂流体験の「真実」を明らかにするものなのか、また、漂流民の意識をどこまで正しく反映しているのか、はなはだおぼつかないのである。しかも、漂流記録の作られ方によって、その問題性の性格や程度もかなり異なることが予想される。漂流記録の史料論を踏まえたうえで、漂流民の自他認識を検討することが求められる所以である。 　本稿は、以上のような問題意識に基づき、文政１３年（１８３０）に備前岡山の神力丸がフィリピンのバターン諸島に漂流した事件を取り上げる。この漂流事件の記録については、別に、史料論的な検討を行っており、本稿の記述はその作業を踏まえたものである。また、この神力丸の漂流事件については、最近、臼井洋輔の労作が発表された。　これは、現在のバターン諸島での生活と漂流記の記述とを比較しながら、主に民俗誌的な関心から漂流事件を追体験しようとしたものであり、教えられるところが多い。　本稿では、それと重複しないように、漂流民の自他認識の一旦を紹介してみたい。 en-copyright= kn-copyright= en-aut-name=KurachiKatsunao en-aut-sei=Kurachi en-aut-mei=Katsunao kn-aut-name=倉地克直 kn-aut-sei=倉地 kn-aut-mei=克直 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20040325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=アメリカ合衆国南西部､コロラド台地に産するエクロジャイト捕獲岩の地球化学的研究:沈み込む海洋地殻の進化に関する考察 kn-title=A geochemical study of the origin of eclogite xenoliths from the Colorado Plateau, southwestern United States: Implications for the evolution of subducted oceanic crust en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=UsuiTomohiro en-aut-sei=Usui en-aut-mei=Tomohiro kn-aut-name=臼井寛裕 kn-aut-sei=臼井 kn-aut-mei=寛裕 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=｢正阿弥勝義と逸見東洋の研究｣-時代の変転が工芸に及ぼす影響について- en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=臼井洋輔 kn-aut-sei=臼井 kn-aut-mei=洋輔 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1985 dt-pub=19851231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=家兎およびヒトリンパ節の微細血管構築の走査電子顕微鏡的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=臼井隆 kn-aut-sei=臼井 kn-aut-mei=隆 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1986 dt-pub=19861231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=15N標識 leucine 負荷による急性肝不全ラットにおける分枝鎖アミノ酸代謝の研究 kn-title=Metabolism of branched-chain amino acids in rats with acute hepatic failure: A tracer study using 15N-leucine en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=臼井裕子 kn-aut-sei=臼井 kn-aut-mei=裕子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1984 dt-pub=19840331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=超音波ドップラー法による下肢閉塞性動脈疾患の血行動態に関する研究 とくに運動負荷試験の有用性について en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=臼井由行 kn-aut-sei=臼井 kn-aut-mei=由行 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=19921231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=ステロイド性大腿骨頭壊死症の病態に関する研究 全身性エリテマトーデス(SLE)を中心に en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=臼井正明 kn-aut-sei=臼井 kn-aut-mei=正明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=20030325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=HMG-CoA還元酵素阻害薬の多面的作用による糖尿病性腎症抑制効果 kn-title=HMG-CoA reductase inhibitor ameliorates diabetic nephropathy by its pleiotropic effects in rats en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=臼井仁美 kn-aut-sei=臼井 kn-aut-mei=仁美 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END