start-ver=1.4
cd-journal=joma
no-vol=110
cd-vols=
no-issue=
article-no=
start-page=1
end-page=6
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A comparative gene analysis reveals a diatom-specific SET domain protein family
kn-title=遺伝子比較解析による珪藻類特異的なSET ドメインタンパク質ファミリーの同定
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=　The silica cell walls of diatoms, which exhibit species-spe-cific micro- and nano- patterned structures are promising candidates for applications in nanotechnology. Previous studies revealed a number of silica cell wall-associated proteins involved in silica formation. However, molecular biological analyses toward understanding of diatom cell wall formation have been mostly limited to model diatom species and general silica formation process in diatoms is still incompletely understood. In this study, to gain a compre-hensive insight into diatom silica biomineralization, tran-scriptome data of three diatom species, Nitzschia palea, Achnanthes kuwaitensis and Pseudoleyanella lunata, were newly developed. The reads obtained from RNA sequencing were assembled into 31,946, 60,767 and 38,314 unique transcripts for N. palea, A. kuwaitensis and P. lunata, respectively. In order to identify the diatom-specific genes, three transcriptome data sets developed in this study and the protein-coding gene sets of five genome-sequenced diatoms were compared. The proteins shared only by eight diatom species that are predicted to possess an endoplasmic reticulum (ER)-targeting signal peptide were selected for further analyses. These include proteins showing homology to silicanin-1, a recently reported diatom-specific protein involved in silica formation, as well as a number of SET domain proteins. The SET domain proteins might be novel diatom-specific family of methyltransferases that may reg-ulate the function of silica formation related proteins or long chain polyamines. The genes encoding the diatom-specific SET domain proteins identified in this study, which were shown to respond to silicon were suggested to be implicated in silica biomineralization.  
en-copyright=
kn-copyright=

en-aut-name=NemotoMichiko
en-aut-sei=Nemoto
en-aut-mei=Michiko
kn-aut-name=根本理子
kn-aut-sei=根本
kn-aut-mei=理子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=岡山大学大学院環境生命科学研究科
en-keyword=Biomineralization
kn-keyword=Biomineralization
en-keyword=Diatom
kn-keyword=Diatom
en-keyword=Silica
kn-keyword=Silica
en-keyword=Protein
kn-keyword=Protein
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=軟骨細胞におけるCCNファミリー遺伝子の糖代謝を介した制御
kn-title=Metabolic regulation of the CCN family genes by glycolysis in chondrocytes
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=AkashiSho
en-aut-sei=Akashi
en-aut-mei=Sho
kn-aut-name=明石翔
kn-aut-sei=明石
kn-aut-mei=翔
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2016
dt-pub=20161227
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=重症薬疹におけるプラキンファミリータンパクに対する抗体プロファイルの長期観察：特に薬剤性過敏症症候群の組織障害との関連性について
kn-title=Longitudinal analysis of antibody profiles against plakins in severe drug eruptions: emphasis on correlation with tissue damage in drug-induced hypersensitivity syndrome and drug reaction with eosinophilia and systemic symptoms
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=TakeharaAya
en-aut-sei=Takehara
en-aut-mei=Aya
kn-aut-name=竹原彩
kn-aut-sei=竹原
kn-aut-mei=彩
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=106
cd-vols=
no-issue=
article-no=
start-page=5
end-page=12
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=20170201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Ginkgo biloba α-fucosidase with activity towards plant complex type N-glycans containing the Lewis a epitope: Purification and characterization
en-subtitle=
kn-subtitle=
en-abstract=　銀杏種子から高分子量 （SDS-PAGE で120 kDa） を有し，α-フコース含有オリゴ糖に活性を示すα-フコシダーゼ（α-fucosidase Gb）を均一に精製した．ルイス a エピトープ含有 N-グリカンを基質とした場合，α-fucosidase Gb の至適 pH は 5.5 付近であることから，本酵素は液胞のような酸性環境で機能していることが示唆された．N?末端アミノ酸配列が化学修飾のため同定できなかったため，本酵素が GH29 ファミリーに属するかどうかは不明である．α-Fucosidase Gb は，Lacto-N-fucopentaose IIIの α1,3-フコース残基やルイス a エピトープ含有の植物複合型N-グリカンのα1,4-フコース残基を加水分解することから，α-フコース含有オリゴ糖やN 型糖タンパク質の分解プロセスに関与することが示唆された．
kn-abstract=　We have identified, and purified to homogeneity, a high molecular weight Ginkgo biloba α-fucosidase (α-fucosidase Gb, 120 kDa estimated by SDS?PAGE) with activity against α-fucosylated oligosaccharides. When a Lewis a epitope-containing N-glycan was used as a substrate, α-fucosidase Gb showed optimum activity at approximately pH 5.5, suggesting that it functions in acidic environments such as the vacuole. It remains uncertain, however, whether this Ginkgo α-fucosidase belongs to the GH29 family, since its N-terminal sequence could not be determined, probably due to a chemical modification. α-Fucosidase Gb showed substantial activity towards the α1,3-fucosyl linkage in Lacto-N-fucopentaose III and an α1,4-fucosyl linkage in the Lewis a epitope found in plant complex type N-glycans, indicating an involvement in the degradation process of α-fucosylated oligosaccharides or N-glycoproteins.
en-copyright=
kn-copyright=

en-aut-name=ItanoSatsuki
en-aut-sei=Itano
en-aut-mei=Satsuki
kn-aut-name=板野紗月
kn-aut-sei=板野
kn-aut-mei=紗月
aut-affil-num=1
ORCID=

en-aut-name=MaedaMegumi
en-aut-sei=Maeda
en-aut-mei=Megumi
kn-aut-name=前田恵
kn-aut-sei=前田
kn-aut-mei=恵
aut-affil-num=2
ORCID=

en-aut-name=Md. Ziaur Rahman
en-aut-sei=Md. Ziaur Rahman
en-aut-mei=
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=KimuraYoshinobu
en-aut-sei=Kimura
en-aut-mei=Yoshinobu
kn-aut-name=木村吉伸
kn-aut-sei=木村
kn-aut-mei=吉伸
aut-affil-num=4
ORCID=

affil-num=1
en-affil=Graduate School of Environmental and life Science, Okayama University
kn-affil=岡山大学大学院環境生命科学研究科

affil-num=2
en-affil=Graduate School of Environmental and life Science, Okayama University
kn-affil=岡山大学大学院環境生命科学研究科

affil-num=3
en-affil=Institute of Food and Radiation Biology, Atomic Energy Research Establishment, Bangladesh Atomic Energy Commission
kn-affil=

affil-num=4
en-affil=Graduate School of Environmental and life Science, Okayama University
kn-affil=岡山大学大学院環境生命科学研究科
en-keyword=α-fucosidase
kn-keyword=α-fucosidase
en-keyword=plant N-glycan
kn-keyword=plant N-glycan
en-keyword=N-glycan degradation
kn-keyword=N-glycan degradation
en-keyword=Ginkgo biloba
kn-keyword=Ginkgo biloba
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2016
dt-pub=20160325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=血小板中のマトリセルラーCCNファミリータンパク質：骨・軟骨再生における役割
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=HaraChikako
en-aut-sei=Hara
en-aut-mei=Chikako
kn-aut-name=原規子
kn-aut-sei=原
kn-aut-mei=規子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=103
cd-vols=
no-issue=
article-no=
start-page=21
end-page=30
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2014
dt-pub=20140201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=コムギ染色体欠損系統を用いた新規活性型レトロトランスポゾン TriRe-1 の分子遺伝学的解析
kn-title=Characterization of a novel retrotransposon TriRe?1 using nullisomic-tetrasomic lines of hexaploid wheat
en-subtitle=
kn-subtitle=
en-abstract=　レトロトランスポゾンは植物ゲノムの主要な構成要素であり，コムギゲノムにおいてはその80ｵを占める．特に
LTR 型レトロトランスポゾンの割合が高く，ゲノムの拡大，配列の多様性およびゲノム構造変異等に大きく寄与し
てきたと考えられている．これら配列は自身のコピー配列を複製し増幅するため，ゲノム中には数百，数千に及ぶコ
ピー配列をもつ．また，ゲノム進化の過程において多数のファミリーを形成してきた．これら多数のファミリーのう
ち，現在でも転移活性を示す活性型ファミリーは，品種間において高い挿入多型を示すことが知られている．このよ
うな挿入多型は，連鎖解析および系統解析等各種遺伝解析に利用可能である. 本研究では，コムギにおける新規活性
型レトロトランスポゾンファミリー TriRe-1 の特徴を詳細に解析した．TriRe-1 は転移に必要なタンパク質をコー
ドする内部配列をもち，また日本で育成されたコムギ近縁品種間においても高い挿入多型を示したため，現在でも転
移活性を有している，もしくはごく最近まで転移していた可能性が高いと考えられた．一方で，コムギ染色体欠損系
統（ナリソミックテトラソミック系統）を用い，TriRe-1 の挿入箇所を比較解析した．その結果，大部分の挿入箇所
は複数の同祖染色体に存在すると考えられたが，Ｂゲノムにおいて最も多くの特異的な挿入箇所が同定された．よっ
て，Ｂゲノム祖先種において活発に増幅してきた可能性が示唆された．今回の結果により，新規活性型レトロトラン
スポゾン TriRe-1 の品種間挿入多型を利用した DNA マーカー，また，各ゲノム（Ａ，Ｂ，Ｄゲノム）特異的な挿
入箇所を利用したゲノム識別性に優れた DNA マーカーの開発の可能性が期待される．
kn-abstract=　Retrotransposons constitute the large fraction (〜80%) of the wheat genome where numerous and
diverse retrotransposon families exist, where especially the long terminal repeat (LTR) retrotransposon
family is known to be predominant. Thus, they have been considered to contribute to the genome
expansion, sequence diversification and the genome structure alternation in the wheat genome. In addition,
the insertion polymorphism of the LTR retrotransposon family among the cultivars has been
known to be quite useful for the genetic analysis such as the linkage mapping and the phylogenetic studies.
Here, we report the characteristics of a novel active LTR retrotransposon family TriRe?1, which
belongs to the Ty1?copia group in the hexaploid wheat (Triticum aestivum L.) genome. This retroelement
appears to encode all proteins required for the transposition and showed high insertion polymorphism
among the hexaploid wheat cultivars, suggesting its potential of transpositional activity with at least
recent transposition during wheat evolution. We studied the chromosomal localization of the TriRe?1
insertion site based on the genome-wide comparative analysis using the nullisomic-tetrasomic lines of
the cultivar Chinese Spring. The results showed that although the majority of the TriRe?1 insertion sites
exist across the homoeologous chromosomes of A, B or D genomes, a higher number of insertions in the
B genome was detected compared to A or D genome, suggesting a specific amplification in the history
of B genome progenitors. In conclusion, a novel LTR retrotransposon TriRe?1 should be valuable for the
development of molecular markers based on insertion polymorphism among the cultivars, and also the
genome-specific TriRe?1 insertion site can be utilized to study evolutional history of wheat genomes.
en-copyright=
kn-copyright=

en-aut-name=MondenYuki
en-aut-sei=Monden
en-aut-mei=Yuki
kn-aut-name=門田有希
kn-aut-sei=門田
kn-aut-mei=有希
aut-affil-num=1
ORCID=

en-aut-name=TakaiTakeru
en-aut-sei=Takai
en-aut-mei=Takeru
kn-aut-name=高井健
kn-aut-sei=高井
kn-aut-mei=健
aut-affil-num=2
ORCID=

en-aut-name=TaharaMakoto
en-aut-sei=Tahara
en-aut-mei=Makoto
kn-aut-name=田原誠
kn-aut-sei=田原
kn-aut-mei=誠
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学
en-keyword=Retrotransposon
kn-keyword=Retrotransposon
en-keyword=Wheat
kn-keyword=Wheat
en-keyword=Molecular markers
kn-keyword=Molecular markers
en-keyword=Nullisomic-tetrasomic lines
kn-keyword=Nullisomic-tetrasomic lines
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20110325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=乳腺上皮細胞の分化とがんにおけるErbBファミリー受容体に関する研究
kn-title=Studies on the ErbB family receptors in mammary epithelial cell differentiation and cancer
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=VaidyanathArun
en-aut-sei=Vaidyanath
en-aut-mei=Arun
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=27
cd-vols=
no-issue=
article-no=
start-page=26
end-page=30
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=201105
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Physiological roles of Runx3 in female reproductive organs in mice
kn-title=雌マウス生殖器官におけるRunx3の役割
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Runx3(Runtdomaintranscriptionfactor3)はRunxファミリーに属する転写因子で雌マウスにおいてRunx3 mRNAは, 卵巣や子宮に発現していた。雌のRunx3(-/-)マウスは不妊であった。Runx3(-/-)マウスは卵胞形成異常を起こしており, 無排卵であった。一方で, 排卵能および黄体形成能は有していた。以上より, Runx3は卵胞形成および排卵制御に関与していることを明らかにした。Runx3(-/-)マウスの子宮は萎縮している。子宮内膜上皮細胞では, E2依存性の細胞増殖が起こらなかった。しかし,子宮内膜間質細胞では, E2, P4存在下で正常に細胞増殖が起きた。以上より, Runx3はE2による子宮の細胞増殖に関与していることを明らかにした｡
en-copyright=
kn-copyright=

en-aut-name=TsuchiyaYukiko
en-aut-sei=Tsuchiya
en-aut-mei=Yukiko
kn-aut-name=土家由起子
kn-aut-sei=土家
kn-aut-mei=由起子
aut-affil-num=1
ORCID=

en-aut-name=SakumaAtsuko
en-aut-sei=Sakuma
en-aut-mei=Atsuko
kn-aut-name=佐久間敦子
kn-aut-sei=佐久間
kn-aut-mei=敦子
aut-affil-num=2
ORCID=

en-aut-name=TakeuchiSakae
en-aut-sei=Takeuchi
en-aut-mei=Sakae
kn-aut-name=竹内栄
kn-aut-sei=竹内
kn-aut-mei=栄
aut-affil-num=3
ORCID=

en-aut-name=TakahashiSumio
en-aut-sei=Takahashi
en-aut-mei=Sumio
kn-aut-name=高橋純夫
kn-aut-sei=高橋
kn-aut-mei=純夫
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院自然科学研究科生体統御学グループ

affil-num=2
en-affil=
kn-affil=岡山大学大学院自然科学研究科生体統御学グループ

affil-num=3
en-affil=
kn-affil=岡山大学大学院自然科学研究科生体統御学グループ

affil-num=4
en-affil=
kn-affil=岡山大学大学院自然科学研究科生体統御学グループ
END

start-ver=1.4
cd-journal=joma
no-vol=30
cd-vols=
no-issue=
article-no=
start-page=65
end-page=79
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2010
dt-pub=20101124
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Chinese Hosts' Intercultural Contact with Japanese International Students : Categorization of Recognition and Coping Based on the AUC?GS Learning Model
kn-title=中国人ホストにおける日本人留学生との異文化接触―AUC-GS学習モデルに基づく異文化への認知と対応の整理―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=日本人留学生と交流経験を持つ、中国人ホスト学生15名及び中国人ホストファミリー6名を対象として、異文化接触における認知と対応について半構造化面接を実施し、AUC-GS学習モデル（田中・中島,2006）に基づき分析を行った。異文化に対する「気づき（A段階）｣「理解（U段階）」「対処（C段階）」の3段階につき、語りからこれらの有無を判断してカテゴリ分けを行った。異文化への気づきはあるが葛藤への理解はなく葛藤場面にも出会ったことがない、というカテゴリに最も多くのホストが分類された。従来から異文化交流の正統派であると考えられてきた、異文化への気づきと葛藤理解と葛藤対処の3段階全てが備わったカテゴリにも、4名の学生が認定された。しかし､異文化葛藤への対処の仕方は、日本人学生のそれとは異なる傾向が認められた。中国人ホストは、日本人学生が実践していたような他者視点に立った調整型の対処方法というよりは（奥西・田中,2009）、自己の視点を機軸とした寛容さの発露により解決を試みていた。
en-copyright=
kn-copyright=

en-aut-name=OkunishiYuri
en-aut-sei=Okunishi
en-aut-mei=Yuri
kn-aut-name=奥西有理
kn-aut-sei=奥西
kn-aut-mei=有理
aut-affil-num=1
ORCID=

en-aut-name=TanakaTomoko
en-aut-sei=Tanaka
en-aut-mei=Tomoko
kn-aut-name=田中共子
kn-aut-sei=田中
kn-aut-mei=共子
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学社会文化科学研究科

affil-num=2
en-affil=
kn-affil=岡山大学社会文化科学研究科
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2009
dt-pub=20090325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=CCNファミリー2/結合組織成長因子は軟骨細胞の増殖と分化を調節し、シグナルコンダクターとしてBMPシグナル伝達経路を制御する
kn-title=CCN family 2/connective tissue growth factor modulates BMP signaling as a signal conductor, which action regulates the proliferation and differentiation of chondrocytes
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=MaedaAzusa
en-aut-sei=Maeda
en-aut-mei=Azusa
kn-aut-name=前田あずさ
kn-aut-sei=前田
kn-aut-mei=あずさ
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=26
cd-vols=
no-issue=1
article-no=
start-page=155
end-page=167
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=20081128
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Hosts in Intercultural Contacts : Empirical Study on Hosts - Guest Exchanges and their Relationships
kn-title=ホストの異文化接触に関する研究課題の展望　−ゲストとの交流と関係性についての実証的研究−
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=本論では､外国からのゲストを迎え入れるホストに関する先行文献を､大学における学生交流及び地域におけるホストファミリー交流という2つの教育的場面の交流に絞って概観する｡大学における
交流をみると､留学交流に関する研究蓄積が多く､特に異文化滞在者であるゲストの困難への関心が高い｡一方で､受け入れ側であるホストについての研究は､比較的僅かである｡大学での交流を巡っては､ホストとゲストの関係が進展しづらい現象が頻繁に注目されており､その原因を究明する試みから､両者間の認識の甑僻が明らかにされてきたoLかし両者の岨鯨を埋めていく方法となると､日本人と留学生の交流実践によって両者の隔たりが埋められるとする簡易な報告はあるが､学術的背景を備えた介入実践などの微密な実証研究はない｡両者の関係改善に向けた､教育的介入の研究の進展が期待される｡地域のホストファミリー交流においては､アカデミックな観点からの研究例は少なく､体験談や経験則の報告が中心となっている｡数少ないアカデミックな立場からの報告には､現状や課題を生理して報告したもの､満足度を調べたもの､特定のコミュニケーション理論に少数のサンプルを当てはめて解釈したものがみられる程度で､体系化されるに至っていない｡すなわち実証研究の質的･量的な不足が指摘できる｡ホストとゲストがどのような葛藤に出くわし､どのようなプロセスを経て関係を改善させていけるのかという問いに対しては､まずフィールドの現実に密着したデータ収集と理論化の試みが求められる｡ホストは教育交流を通じて変容するのか､それはどのような道筋を経るのか､変容は教育的に促せるのか､人為学習と自然学習はどう異なるのかなどが､今後の解明を要する課題と考えられる｡ホストとゲストの接触を巡る研究がホストの側からも蓄積されていけば､両者のダイナミックな関係がより解明できるものと期待される｡
en-copyright=
kn-copyright=

en-aut-name=OkunishiYuri
en-aut-sei=Okunishi
en-aut-mei=Yuri
kn-aut-name=奥西有理
kn-aut-sei=奥西
kn-aut-mei=有理
aut-affil-num=1
ORCID=

en-aut-name=TanakaTomoko
en-aut-sei=Tanaka
en-aut-mei=Tomoko
kn-aut-name=田中共子
kn-aut-sei=田中
kn-aut-mei=共子
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=106
cd-vols=
no-issue=5-6
article-no=
start-page=549
end-page=560
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=1994
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Clinical studies on plasma cyclic nucleotide levels in acute leukemia
kn-title=急性白血病における血漿cyclic nucleotides動態に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Plasma levels of cyclic nucleotides were measured in 71 patients with acute leukemia [50 patients with acute nonlymphocytic leukemia (ANLL), five patients with hypoplastic leuke-mia, and 16 patients with acute lymphocytic leukemia (ALL)], five patients with myelodysplas-tic syndrome (MDS), and 47 healthy volunteers. The cyclic GMP (c-GMP) level, cyclic AMP (c-AMP) level, and c-AMP/c-GMP ratio in healthy volunteers were 15.74±5.10 pmol/ml, 3.20±1.15 pmol/ml and 5.39±2.18, respectively. In the patients with untreated acute leukemia other than hypoplastic leukemia, c-GMP levels were significantly elevated (ANLL : 11.31±13.61 pmol/ml ; ALL : 10.66±7.23 pmol/ml) and c-AMP/c-GMP ratios were significantly reduced (ANLL : 2.01±1.03 ; ALl : 1.66±1.03). These values normalized at remission, than increased or decreased again with recurrence of the disease. Although patients with MDS showed normal c-GMP levels or c-AMP/c-GMP rations, these values were increased or decreased when progression to acute leukemia occurred. There was correlation between c-GMP levels and peripheral leukocyte counts (r=0.429,p<0.05), plasma c-GMP levels and peripheral leukemic cell counts (r=0.412,p<0.05), c-AMP/c-GMP rations and peripheral leukocyte counts (r=-0.577,p<0.05), c-AMP/c-GMP rations and periph-eral leukemic cell counts (r=-0.512,p<0.05), and c-AMP/c-GMP rations and periph-eral leukemic cell counts (r=-0.512,p<0.05), and c-AMP/c-GMP rations and maximum counts of colonies derived from leukemic blast progenitors (r=-0.996,p<0.01). Since plasma levls of cyclic nucleotides reflect the leukemic cell proliferation, measurement of these nucleotides was considered useful for monitoring leukemic cell volume.
en-copyright=
kn-copyright=

en-aut-name=NonakaKenichi
en-aut-sei=Nonaka
en-aut-mei=Kenichi
kn-aut-name=野中研一
kn-aut-sei=野中
kn-aut-mei=研一
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第二内科学教室
en-keyword=血漿 cyclic nucleotides
kn-keyword=血漿 cyclic nucleotides
en-keyword=急性白血病
kn-keyword=急性白血病
en-keyword=低形成型白血病
kn-keyword=低形成型白血病
END

start-ver=1.4
cd-journal=joma
no-vol=106
cd-vols=
no-issue=3-4
article-no=
start-page=401
end-page=413
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=1994
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Kinetics of heat shock protein 72 in HeLa cells after treatment with heating and/or anticancer agents analyzed by a laser cytometer
kn-title=レーザーサイトメーターを用いたheat shock protein 72の加温および抗癌剤添加による動態の検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Heat shock proteins (HSPs) are regarded as the proteins most related to the development of thermotolerance. Recently, not only their role in thermotolerance, but also their role in resistance to anticancer agents is gathering concern. In this study, the kinetics of hsp 72 in HeLa cells treated with heating and/or anticancer agents were studied. Hsp 72 was immuno-stained by the indirect fluorescent technique using a monoclonal anti-hsp 72 antibody (Amer-sham). The staining pattern was observed and analyzed using a laser cytometer, ACAS 570 (Meridian). Hsp 72 was normally found in the cytoplasm at 37℃ and moved rapidly into the nucleus with heating at 43℃ for 2 hours. It then returned to the cytoplasm 4 to 6 hours after heating. The hsp 72 content reached a peak at 8 hours after heating. Hsp 72 was induced in all cells treated with cisplation, adriamycin, peplomycin, or etoposide for 48 hours. In the cells treated with both heating at 43℃ for 2 hours and these anticancer agents, hsp 72 induction was most suppressed by adriamycin. However, translocation of hsp 72 to the nucleus was specific for heating and was not affected by the anticancer agents. By laser cytometry the intracellular localization of hsp 72 and the changes of its content were simultaneously detected, Moreover, the change pattern of hsp 72 content measured by laser cytomtry coincided with that measured by the Western blotting procedure.
en-copyright=
kn-copyright=

en-aut-name=SawaiHideaki
en-aut-sei=Sawai
en-aut-mei=Hideaki
kn-aut-name=澤井秀秋
kn-aut-sei=澤井
kn-aut-mei=秀秋
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部産科婦人科学教室
en-keyword=レーザーサイトメーター
kn-keyword=レーザーサイトメーター
en-keyword=heat shock proteinｎ
kn-keyword=heat shock proteinｎ
en-keyword=抗癌剤
kn-keyword=抗癌剤
END

start-ver=1.4
cd-journal=joma
no-vol=106
cd-vols=
no-issue=1-2
article-no=
start-page=61
end-page=70
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=199402
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Interleukin-2 receptor α(p55) mRNA expression in alveolar lymphocytes of patients with sarcoidosis
kn-title=サルコイドーシス患者肺胞リンパ球のInterleukin-2 receptor α(IL-2R α) mRAの発現に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=T-lymphocytosis was detected in bronchoalveolar lavage fluid of patients with sarcoidosis. To clarify the mechanism of this phenomenon, interleukin-2 receptor(IL-2R) α gene expres-sion of lymphocytes recovered from bronchoalveolar lavage fluid was investigated in 8 patients with sarcoidosis and 5 healthy individuals, using reverse transcription polymerase chain reactin (RT-PCR). Cytoplasmic RNA derived from alveolar lymphocytes was reverse transcribed by RAV-2 reverse transcriptase to cDNA. The cDNA produced by reverse transcription was subjected to PCR. The primers of IL-2R α were utilized and a template derived from IL-2R mRNA was amplified by PCR. Southern blot analysis using 32P labeled cDNA probe for IL-2R α was performed followed by PCR. The intensities of IL-2R mRNA expression in Southern blot analysis were closely correlated to the cell numbers determined in RT-PCR.
 All patients with sarcoidosis had higher expression of IL-2R α mRNA transcript in alveolar lymphoctes compared with healty with healthy individuals. Moreover, the expression increased after stimulation by Propionibacterium acnes in 5 of 6 patents with sarcoidosis. These findings suggest that alvalar T-lymphocytes in the patients with sarcoidosis were actiated and played a central role in the pathogenesis of sarcoidosis.
en-copyright=
kn-copyright=

en-aut-name=NishizakiHiroshi
en-aut-sei=Nishizaki
en-aut-mei=Hiroshi
kn-aut-name=西崎浩
kn-aut-sei=西崎
kn-aut-mei=浩
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第二内科学教室
en-keyword=sarcoidosis
kn-keyword=sarcoidosis
en-keyword=interleukin-2 receptor α
kn-keyword=interleukin-2 receptor α
en-keyword=reverse transcription-polymerase chain reaction
kn-keyword=reverse transcription-polymerase chain reaction
en-keyword=alveolar lymphocyte
kn-keyword=alveolar lymphocyte
en-keyword=Propionibacterium acnes
kn-keyword=Propionibacterium acnes
END

start-ver=1.4
cd-journal=joma
no-vol=114
cd-vols=
no-issue=3
article-no=
start-page=253
end-page=259
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2003
dt-pub=20030131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=癌抑制遺伝子 ING ファミリーの構造と機能
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=GunduzMehmet
en-aut-sei=Gunduz
en-aut-mei=Mehmet
kn-aut-name=グンデウズメーメット
kn-aut-sei=グンデウズ
kn-aut-mei=メーメット
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医歯学総合研究科　病態機構学講座，口腔病理病態学分野
en-keyword=ING 1
kn-keyword=ING 1
en-keyword=ING 3
kn-keyword=ING 3
en-keyword=ING ファミリー
kn-keyword=ING ファミリー
en-keyword=癌抑制遺伝子
kn-keyword=癌抑制遺伝子
en-keyword=LOH
kn-keyword=LOH
END

start-ver=1.4
cd-journal=joma
no-vol=117
cd-vols=
no-issue=1
article-no=
start-page=17
end-page=20
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=20050520
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=グリア境界膜に局在する新規遺伝子「リミトリン」の発見
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=米澤朋子
kn-aut-sei=米澤
kn-aut-mei=朋子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院医歯学総合研究科分子医化学
en-keyword=血液脳関門
kn-keyword=血液脳関門
en-keyword=アストロサイト
kn-keyword=アストロサイト
en-keyword=基底膜
kn-keyword=基底膜
en-keyword=グリア境界
kn-keyword=グリア境界
en-keyword=イムノグロブリンスーパーファミリー
kn-keyword=イムノグロブリンスーパーファミリー
END

start-ver=1.4
cd-journal=joma
no-vol=118
cd-vols=
no-issue=1
article-no=
start-page=17
end-page=21
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2006
dt-pub=20060501
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=原発性肺高血圧症の病態形成における骨形成蛋白（BMP）�T型受容体の関与とその意義：肺動脈血管平滑筋細胞を用いた検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=武田昌也
kn-aut-sei=武田
kn-aut-mei=昌也
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=大塚文男
kn-aut-sei=大塚
kn-aut-mei=文男
aut-affil-num=2
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=中村一文
kn-aut-sei=中村
kn-aut-mei=一文
aut-affil-num=3
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=稲垣兼一
kn-aut-sei=稲垣
kn-aut-mei=兼一
aut-affil-num=4
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=鈴木二郎
kn-aut-sei=鈴木
kn-aut-mei=二郎
aut-affil-num=5
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=三浦大志
kn-aut-sei=三浦
kn-aut-mei=大志
aut-affil-num=6
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=藤尾栄起
kn-aut-sei=藤尾
kn-aut-mei=栄起
aut-affil-num=7
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=松原広己
kn-aut-sei=松原
kn-aut-mei=広己
aut-affil-num=8
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=伊達洋至
kn-aut-sei=伊達
kn-aut-mei=洋至
aut-affil-num=9
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=大江透
kn-aut-sei=大江
kn-aut-mei=透
aut-affil-num=10
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=槇野博史
kn-aut-sei=槇野
kn-aut-mei=博史
aut-affil-num=11
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　腎・免疫・内分泌代謝内科学

affil-num=2
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　腎・免疫・内分泌代謝内科学

affil-num=3
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　循環器内科学

affil-num=4
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　腎・免疫・内分泌代謝内科学

affil-num=5
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　腎・免疫・内分泌代謝内科学

affil-num=6
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　循環器内科学

affil-num=7
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　循環器内科学

affil-num=8
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　循環器内科学

affil-num=9
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　腫瘍・胸部外科学

affil-num=10
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　循環器内科学

affil-num=11
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科　腎・免疫・内分泌代謝内科学
en-keyword=原発性肺高血圧症 (PPH)
kn-keyword=原発性肺高血圧症 (PPH)
en-keyword=骨形成蛋白 (BMP)
kn-keyword=骨形成蛋白 (BMP)
en-keyword=肺動脈血管平滑筋細胞
kn-keyword=肺動脈血管平滑筋細胞
en-keyword=TGF-β スーパーファミリー
kn-keyword=TGF-β スーパーファミリー
en-keyword=BMP IＢ型受容体 (ALK-6)
kn-keyword=BMP IＢ型受容体 (ALK-6)
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=20080325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=軟骨細胞および骨芽細胞分化におけるCCNファミリータンパク質の機能解析
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=KawakiHarumi
en-aut-sei=Kawaki
en-aut-mei=Harumi
kn-aut-name=川木晴美
kn-aut-sei=川木
kn-aut-mei=晴美
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=3
cd-vols=
no-issue=2
article-no=
start-page=145
end-page=149
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1995
dt-pub=1995
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Cloning of PCR-Products Encoding Potassium Channel Proteins from Mesembryanthemum crystallinum
kn-title=Mesembryanthemum crystallinum(ice plant)におけるカリウムチャンネルをコードするPCR産物のクローニング
en-subtitle=
kn-subtitle=
en-abstract=耐塩性、耐乾性の極めて高い Mesembryanthemum crystallinum からPCR法を用いてカリウムチャンネル遺伝子断片を得た。2つのクローンが独立に得られたが、互いによく似ていて、シロイヌナズナのカリウムチャンネルとは67から88％の相同性を示した。サザンハイブリダイゼーションの結果から、今回得られた遺伝子はシングルコピーであり、またカリウムチャンネル遺伝子ファミリーが存在する可能性が示唆された。
kn-abstract=Gene fragments of potassium channels were cloned from Mesembryanthemum crystallinum by using RT-PCR (reverse transcription-polymerase chain reaction). The two fragments were isolated independently and showed high similarity with each other. About 80% identity was found between the two fragments and potassium-channel genes of Arabidopsis. Southern hybridization indicated that the potassium channel gene may be a single copy gene or that a small gene family of potassium channels exists.
en-copyright=
kn-copyright=

en-aut-name=KatsuharaMaki
en-aut-sei=Katsuhara
en-aut-mei=Maki
kn-aut-name=且原真木
kn-aut-sei=且原
kn-aut-mei=真木
aut-affil-num=1
ORCID=

en-aut-name=BohnertHans J.
en-aut-sei=Bohnert
en-aut-mei=Hans J.
kn-aut-name=BohnertHans J.
kn-aut-sei=Bohnert
kn-aut-mei=Hans J.
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学
en-keyword=Mesembryanthemum crystallinum
kn-keyword=Mesembryanthemum crystallinum
en-keyword=Potassium channel
kn-keyword=Potassium channel
en-keyword=RT-PCR
kn-keyword=RT-PCR
END

start-ver=1.4
cd-journal=joma
no-vol=87
cd-vols=
no-issue=1
article-no=
start-page=53
end-page=58
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1998
dt-pub=199802
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Structural Analysis of the mde Operon lnvolved in L-Methionine Degradative Metabolism of Pseudomonas putida
kn-title=Pseudomonas putida のＬ−メチオニン分解系オペロンの解析
en-subtitle=
kn-subtitle=
en-abstract=mdeオペロン及びその上流調節遺伝子(mdeR)がPseudomonas putida染色体DNAからクローニングされ、これらの遺伝子の塩基配列が決定された。mdeオペロンは、L-メチオニン分解代謝に伴われる2つの構造遺伝子mdeA (L-メチオニン　γ-リアーゼ遺伝子)及び、mdeB(ピルビン酸デヒドロゲナーゼ複合体のE1成分に相同性のあるタンパク質をコードする遺伝子)を含んでいた。ロー因子非依存型のターミネーター構造がmdeBのすぐ下流に存在し、α-ケト酸デヒドロゲナーゼ複合体の他の成分に相当するオープンリーディングフレームは見られなかった。mdeB産物が大腸菌中で過剰発現されたとき、その細胞抽出液は、ピルビン酸よりもむしろα-ケト酪酸に対し高い特異性を持つE1活性を示した。すなわちmdeB遺伝子は新規のE1成分であるα-ケト酪酸デヒドロゲナーゼE1成分をコードしており、L-メチオニンからL-メチオニンγ-リアーゼによって生産されたα-ケト酪酸の代謝に、mdeBが重要な役割を果たすことが示唆された。さらに我々は、mdeA遺伝子の翻訳開始点から127bp上流反対方向にコードされるmdeR遺伝子を見い出した。mdeR産物は、ロイシン応答調節タンパク質(Lrp)ファミリーの一つとして同定され、mdeABオペロンの発現に必須な正の調整因子として作用することが明らかとなった。
kn-abstract=The mde operon and an upstream regulatory gene (mdeR) have been cloned and sequenced from Pseudomonas putida chromosomal DNA. The mde operon contains two structural genes involved in L-methionine degradative metabolism, which are mdeA (L-methionine γ-lyase gene) and mdeB (a gene encoding a homologous protein to the E1 component of pyruvate dehydrogenase complex). A rho-independent terminator was present just downstream of mdeB and open reading frames corresponding to other components of α-keto acid dehydrogenase complex were not found. When the mdeB gene product was overproduced in Escherichia coli, the E1 activity of the cell extract showed high specificity for α-ketobutyrate rather than pyruvate. these results suggest that mdeB encodes a novel E1 component, α-ketobutyrate dehydrogenase E1 component, and plays an important role in the metabolism of α-ketobutyrate produced by L-methionine γ-lyase from L-methionine. In addition,we found that mdeR gene was located on the opposite strand and began at 127 bp from the translational start site of mdeA. The mdeR gene product has been idetified as a member of the leucine responsive regulatory protein (Lrp) family and revealed to act as an essential positive regulator allowing the expression of the mdeAB operon.
en-copyright=
kn-copyright=

en-aut-name=InoueHiroyuki
en-aut-sei=Inoue
en-aut-mei=Hiroyuki
kn-aut-name=井上浩之
kn-aut-sei=井上
kn-aut-mei=浩之
aut-affil-num=1
ORCID=

en-aut-name=TamuraTakashi
en-aut-sei=Tamura
en-aut-mei=Takashi
kn-aut-name=田村隆
kn-aut-sei=田村
kn-aut-mei=隆
aut-affil-num=2
ORCID=

en-aut-name=InagakiKenji
en-aut-sei=Inagaki
en-aut-mei=Kenji
kn-aut-name=稲垣賢二
kn-aut-sei=稲垣
kn-aut-mei=賢二
aut-affil-num=3
ORCID=

en-aut-name=TanakaHidehiko
en-aut-sei=Tanaka
en-aut-mei=Hidehiko
kn-aut-name=田中英彦
kn-aut-sei=田中
kn-aut-mei=英彦
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学

affil-num=4
en-affil=
kn-affil=岡山大学
en-keyword=L-methionine
kn-keyword=L-methionine
en-keyword=α-ketobutyrate
kn-keyword=α-ketobutyrate
en-keyword=mde operon
kn-keyword=mde operon
en-keyword=pyruvate dehydrogenase E1 component
kn-keyword=pyruvate dehydrogenase E1 component
en-keyword=leucine responsive regulatory protein
kn-keyword=leucine responsive regulatory protein
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=20050325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=新規CTX遺伝子ファミリーadipocyte adhesion molecule(ACAM)は,脂肪細胞の分化と肥満形成に関与する
kn-title=Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene part name="family", implicated in adipocyte maturation and development of obesity
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=EguchiJun
en-aut-sei=Eguchi
en-aut-mei=Jun
kn-aut-name=江口潤
kn-aut-sei=江口
kn-aut-mei=潤
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1990
dt-pub=19900328
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=好中球細胞膜糖蛋白(LFA-1フｧミリー)が関与する歯周病の病態研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=小林充治
kn-aut-sei=小林
kn-aut-mei=充治
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2003
dt-pub=20031231
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=イムノグロブリンスーパーファミリーに属するリミトリンはアストロサイト終足が形成するグリア境界膜に局在する
kn-title=Limitrin, a Novel Immunoglobulin Superpart name="family" Protein Localized to Glia Limitans Formed by Astrocyte Endfeet
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=YonezawaTomoko
en-aut-sei=Yonezawa
en-aut-mei=Tomoko
kn-aut-name=米澤朋子
kn-aut-sei=米澤
kn-aut-mei=朋子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2001
dt-pub=20010325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=ヒトRBフｧミリーp107遺伝子の全体構造とB細胞リンパ腫細胞株における遺伝子欠失についての解析
kn-title=Structure of the human retinoblastoma-related p107 gene and its intragenic deletion in a B-cell lymphoma cell line
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=市村浩一
kn-aut-sei=市村
kn-aut-mei=浩一
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=角化細胞分化過程におけるbcl-2 フｧミリーの発現
kn-title=Expression of the bcl-'2 part name="family" in the course of keratinocyte differentiation
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=TomkovaHana
kn-aut-sei=Tomkova
kn-aut-mei=Hana
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
en-keyword=Bcl-2
kn-keyword=Bcl-2
en-keyword=ヒト角化細胞
kn-keyword=ヒト角化細胞
en-keyword=bax遺伝子
kn-keyword=bax遺伝子
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1998
dt-pub=19980325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=FACIT コラーゲンフｧミリーの祖先遺伝子より進化したと思われるヒトXIX 型コラーゲンα1 鎖遺伝子の構造
kn-title=Structure of the human field name="type" XIX collagen(COL19A1)gene, which suggests it has arisen from an ancestor gene of the FACIT part name="family"
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=MohammedKhaleduzzaman
kn-aut-sei=Mohammed
kn-aut-mei=Khaleduzzaman
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END