start-ver=1.4 cd-journal=joma no-vol=8 cd-vols= no-issue=4 article-no= start-page=509 end-page=518 dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20191204 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Effects of loading contact on electric-power generation of lead zirconate titanate piezoelectric ceramic plate en-subtitle= kn-subtitle= en-abstract= kn-abstract=To better understand the generation of electric power for piezoelectric PbZrTiO3 (PZT) ceramic plate (phi 25 mm), an attempt was made to investigate experimentally and numerically electric-power generation characteristics during cyclic bending under various loading fixtures (phi 0-phi 20 mm), i.e., different contact areas. Increasing the load-contact area on the PZT ceramic leads to a nonlinear decrease in the generated voltage. Decreasing contact area basically enhances the generated voltage, although the voltage saturates during loading when the contact area is less than phi 5 mm. A similar voltage is generated for phi 0 and phi 5 mm, which is attributed to strain status (ratio of compressive and tensile strain) and material failure due to different stress distribution in the PZT ceramic. On the basis of the obtained electric generation voltage, suitable loading conditions are clarified by loading with the phi 5 mm fixture, which generates a higher voltage and a longer lifetime of the PZT ceramic. From this approach, it is appeared that the area contact with the area ratio of 0.04 (phi 5 mm/phi 20 mm) is suitable to obtain the high efficiency of the electric voltage. en-copyright= kn-copyright= en-aut-name=OkayasuMitsuhiro en-aut-sei=Okayasu en-aut-mei=Mitsuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OgawaTsukasa en-aut-sei=Ogawa en-aut-mei=Tsukasa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= en-keyword=piezoelectric ceramic kn-keyword=piezoelectric ceramic en-keyword=lead zirconate titanate ceramic kn-keyword=lead zirconate titanate ceramic en-keyword=electric power generation kn-keyword=electric power generation END start-ver=1.4 cd-journal=joma no-vol=6 cd-vols= no-issue=1 article-no= start-page=25 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20200116 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Recurring radiation-induced angiosarcoma of the breast that was treated with paclitaxel chemotherapy: a case report en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background Angiosarcoma of the breast is very rare and can be divided into primary and secondary angiosarcoma. Radiation-induced angiosarcoma (RIAS) is classified as secondary angiosarcoma. Diagnosis of RIAS is difficult due to its rarity, and the interpretation of pathological imaging is complicated. In the National Comprehensive Care Network (NCCN) guidelines, the first choice of treatment is surgery with negative margins. Adjuvant radiotherapy (RT) for close soft tissue margins should be considered. Preoperative or adjuvant chemotherapy of nonmetastatic disease is not recommended for angiosarcoma. We report a case of RIAS, which was impossible to diagnose with core needle biopsy (CNB) but was diagnosed by excisional biopsy. The patient was then administered adjuvant chemotherapy using conjugated paclitaxel (PTX).
Case presentation A 62-year-old woman noticed a tumor in her right breast. She had a history of right breast cancer and had undergone breast-conserving surgery, RT, and tamoxifen therapy 8 years previously. CNB, which was performed twice, was inconclusive. The tumor was surgically excised and pathological analysis yielded a diagnosis of angiosarcoma. She then underwent a right mastectomy. One month after she underwent right mastectomy, a nodule reappeared on the skin of her right breast, and excisional biopsy revealed recurrence of angiosarcoma. A few weeks later another nodule reappeared near the post-operative scar and excisional biopsy revealed recurrence of angiosarcoma. We assumed that surgical therapy was insufficient because the patient experienced relapse of angiosarcoma after complete mastectomy. After the second recurrence, we treated her with systemic chemotherapy using PTX. There was no evidence of recurrence 8 months after chemotherapy.
Conclusion Although angiosarcoma is difficult to diagnose, many patients have a poor prognosis. Therefore, prompt treatment intervention is desired. Moreover, there is little evidence regarding adjuvant therapy of angiosarcoma since it is a rare disease. We consider that adjuvant therapy helped to effectively prevent recurrence in the patient after complete excision. en-copyright= kn-copyright= en-aut-name=SuzukiYoko en-aut-sei=Suzuki en-aut-mei=Yoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TaniguchiKohei en-aut-sei=Taniguchi en-aut-mei=Kohei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HatonoMinami en-aut-sei=Hatono en-aut-mei=Minami kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KajiwaraYukiko en-aut-sei=Kajiwara en-aut-mei=Yukiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=AbeYuko en-aut-sei=Abe en-aut-mei=Yuko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KawadaKengo en-aut-sei=Kawada en-aut-mei=Kengo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=TsukiokiTakahiro en-aut-sei=Tsukioki en-aut-mei=Takahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KochiMariko en-aut-sei=Kochi en-aut-mei=Mariko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=NishiyamaKeiko en-aut-sei=Nishiyama en-aut-mei=Keiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=IwamotoTakayuki en-aut-sei=Iwamoto en-aut-mei=Takayuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=IkedaHirokuni en-aut-sei=Ikeda en-aut-mei=Hirokuni kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=ShienTadahiko en-aut-sei=Shien en-aut-mei=Tadahiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=TairaNaruto en-aut-sei=Taira en-aut-mei=Naruto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=TabataMasahiro en-aut-sei=Tabata en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= en-aut-name=YanaiHiroyuki en-aut-sei=Yanai en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=15 ORCID= en-aut-name=DoiharaHiroyoshi en-aut-sei=Doihara en-aut-mei=Hiroyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=16 ORCID= affil-num=1 en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital kn-affil= affil-num=2 en-affil=Department of Pathological diagnosis, Okayama University Japan Hospital kn-affil= affil-num=3 en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital kn-affil= affil-num=4 en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital kn-affil= affil-num=5 en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital kn-affil= affil-num=6 en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital kn-affil= affil-num=7 en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital kn-affil= affil-num=8 en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital kn-affil= affil-num=9 en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital kn-affil= affil-num=10 en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital kn-affil= affil-num=11 en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital kn-affil= affil-num=12 en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital kn-affil= affil-num=13 en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital kn-affil= affil-num=14 en-affil=Department of Hematology, Oncology, Respiratory, and Allergy Medicine, Okayama University Japan Hospital kn-affil= affil-num=15 en-affil=Department of Pathological diagnosis, Okayama University Japan Hospital kn-affil= affil-num=16 en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital kn-affil= en-keyword=Radiation-induced angiosarcoma kn-keyword=Radiation-induced angiosarcoma en-keyword=Radiotherapy kn-keyword=Radiotherapy en-keyword=Breast-conserving surgery kn-keyword=Breast-conserving surgery en-keyword=Breast cancer kn-keyword=Breast cancer en-keyword=Paclitaxel therapy kn-keyword=Paclitaxel therapy en-keyword=Adjuvant therapy of angiosarcoma kn-keyword=Adjuvant therapy of angiosarcoma END start-ver=1.4 cd-journal=joma no-vol=9 cd-vols= no-issue=1 article-no= start-page=22 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230511 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Delayed emergence from anesthesia caused by an intraoperative cerebral embolism of a malignant peripheral nerve sheath tumor in a neurofibromatosis type 1 patient: a case report en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background@Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas which commonly arise from neurofibromatosis type 1. Lung metastases of the tumors are well-known, but intraoperative cerebral tumor embolisms of MPNSTs have not been reported in literature.
Case presentation@A 52-year-old female patient with neurofibromatosis type 1 underwent a right lung partial resection for lung tumors. She was extubated after adequate recovery of spontaneous breathing; however, she could not respond to verbal commands. In the intensive care unit, her neurological examination revealed conjugate eye deviation, right hemiparalysis, and aphasia. Magnetic resonance imaging revealed acute cerebral ischemia, so she underwent an endovascular thrombectomy. The histopathological diagnosis of emboli was a MPNST, which was identical with that of the resected lung tumor.
Conclusion@We report the first case of delayed emergence caused by a cerebral tumor embolism of MPNST during partial lung resection. en-copyright= kn-copyright= en-aut-name=KawanoKeishi en-aut-sei=Kawano en-aut-mei=Keishi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TaniMakiko en-aut-sei=Tani en-aut-mei=Makiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MorimatsuHiroshi en-aut-sei=Morimatsu en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil=Department of Anesthesiology, Okayama City Hospital kn-affil= affil-num=2 en-affil=Department of Anesthesiology and Resuscitology, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama University Hospital kn-affil= affil-num=3 en-affil=Department of Anesthesiology and Resuscitology, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama University Hospital kn-affil= en-keyword=Delayed emergence kn-keyword=Delayed emergence en-keyword=Cerebral tumor embolism kn-keyword=Cerebral tumor embolism en-keyword=Endovascular thrombectomy kn-keyword=Endovascular thrombectomy en-keyword=Neurofibromatosis type 1 kn-keyword=Neurofibromatosis type 1 en-keyword=Malignant peripheral nerve sheath tumor kn-keyword=Malignant peripheral nerve sheath tumor en-keyword=Lung surgery kn-keyword=Lung surgery END