start-ver=1.4
cd-journal=joma
no-vol=9
cd-vols=
no-issue=1
article-no=
start-page=22
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=20230511
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Delayed emergence from anesthesia caused by an intraoperative cerebral embolism of a malignant peripheral nerve sheath tumor in a neurofibromatosis type 1 patient: a case report
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Background@Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas which commonly arise from neurofibromatosis type 1. Lung metastases of the tumors are well-known, but intraoperative cerebral tumor embolisms of MPNSTs have not been reported in literature.
Case presentation@A 52-year-old female patient with neurofibromatosis type 1 underwent a right lung partial resection for lung tumors. She was extubated after adequate recovery of spontaneous breathing; however, she could not respond to verbal commands. In the intensive care unit, her neurological examination revealed conjugate eye deviation, right hemiparalysis, and aphasia. Magnetic resonance imaging revealed acute cerebral ischemia, so she underwent an endovascular thrombectomy. The histopathological diagnosis of emboli was a MPNST, which was identical with that of the resected lung tumor.
Conclusion@We report the first case of delayed emergence caused by a cerebral tumor embolism of MPNST during partial lung resection.
en-copyright=
kn-copyright=
en-aut-name=KawanoKeishi
en-aut-sei=Kawano
en-aut-mei=Keishi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=TaniMakiko
en-aut-sei=Tani
en-aut-mei=Makiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=MorimatsuHiroshi
en-aut-sei=Morimatsu
en-aut-mei=Hiroshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
affil-num=1
en-affil=Department of Anesthesiology, Okayama City Hospital
kn-affil=
affil-num=2
en-affil=Department of Anesthesiology and Resuscitology, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama University Hospital
kn-affil=
affil-num=3
en-affil=Department of Anesthesiology and Resuscitology, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama University Hospital
kn-affil=
en-keyword=Delayed emergence
kn-keyword=Delayed emergence
en-keyword=Cerebral tumor embolism
kn-keyword=Cerebral tumor embolism
en-keyword=Endovascular thrombectomy
kn-keyword=Endovascular thrombectomy
en-keyword=Neurofibromatosis type 1
kn-keyword=Neurofibromatosis type 1
en-keyword=Malignant peripheral nerve sheath tumor
kn-keyword=Malignant peripheral nerve sheath tumor
en-keyword=Lung surgery
kn-keyword=Lung surgery
END
start-ver=1.4
cd-journal=joma
no-vol=6
cd-vols=
no-issue=1
article-no=
start-page=25
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2020
dt-pub=20200116
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Recurring radiation-induced angiosarcoma of the breast that was treated with paclitaxel chemotherapy: a case report
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Background Angiosarcoma of the breast is very rare and can be divided into primary and secondary angiosarcoma. Radiation-induced angiosarcoma (RIAS) is classified as secondary angiosarcoma. Diagnosis of RIAS is difficult due to its rarity, and the interpretation of pathological imaging is complicated. In the National Comprehensive Care Network (NCCN) guidelines, the first choice of treatment is surgery with negative margins. Adjuvant radiotherapy (RT) for close soft tissue margins should be considered. Preoperative or adjuvant chemotherapy of nonmetastatic disease is not recommended for angiosarcoma. We report a case of RIAS, which was impossible to diagnose with core needle biopsy (CNB) but was diagnosed by excisional biopsy. The patient was then administered adjuvant chemotherapy using conjugated paclitaxel (PTX).
Case presentation A 62-year-old woman noticed a tumor in her right breast. She had a history of right breast cancer and had undergone breast-conserving surgery, RT, and tamoxifen therapy 8 years previously. CNB, which was performed twice, was inconclusive. The tumor was surgically excised and pathological analysis yielded a diagnosis of angiosarcoma. She then underwent a right mastectomy. One month after she underwent right mastectomy, a nodule reappeared on the skin of her right breast, and excisional biopsy revealed recurrence of angiosarcoma. A few weeks later another nodule reappeared near the post-operative scar and excisional biopsy revealed recurrence of angiosarcoma. We assumed that surgical therapy was insufficient because the patient experienced relapse of angiosarcoma after complete mastectomy. After the second recurrence, we treated her with systemic chemotherapy using PTX. There was no evidence of recurrence 8 months after chemotherapy.
Conclusion Although angiosarcoma is difficult to diagnose, many patients have a poor prognosis. Therefore, prompt treatment intervention is desired. Moreover, there is little evidence regarding adjuvant therapy of angiosarcoma since it is a rare disease. We consider that adjuvant therapy helped to effectively prevent recurrence in the patient after complete excision.
en-copyright=
kn-copyright=
en-aut-name=SuzukiYoko
en-aut-sei=Suzuki
en-aut-mei=Yoko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=TaniguchiKohei
en-aut-sei=Taniguchi
en-aut-mei=Kohei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=HatonoMinami
en-aut-sei=Hatono
en-aut-mei=Minami
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=KajiwaraYukiko
en-aut-sei=Kajiwara
en-aut-mei=Yukiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=AbeYuko
en-aut-sei=Abe
en-aut-mei=Yuko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=KawadaKengo
en-aut-sei=Kawada
en-aut-mei=Kengo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=TsukiokiTakahiro
en-aut-sei=Tsukioki
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=KochiMariko
en-aut-sei=Kochi
en-aut-mei=Mariko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=NishiyamaKeiko
en-aut-sei=Nishiyama
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=IwamotoTakayuki
en-aut-sei=Iwamoto
en-aut-mei=Takayuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
en-aut-name=IkedaHirokuni
en-aut-sei=Ikeda
en-aut-mei=Hirokuni
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=
en-aut-name=ShienTadahiko
en-aut-sei=Shien
en-aut-mei=Tadahiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=
en-aut-name=TairaNaruto
en-aut-sei=Taira
en-aut-mei=Naruto
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=
en-aut-name=TabataMasahiro
en-aut-sei=Tabata
en-aut-mei=Masahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=
en-aut-name=YanaiHiroyuki
en-aut-sei=Yanai
en-aut-mei=Hiroyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=
en-aut-name=DoiharaHiroyoshi
en-aut-sei=Doihara
en-aut-mei=Hiroyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=16
ORCID=
affil-num=1
en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital
kn-affil=
affil-num=2
en-affil=Department of Pathological diagnosis, Okayama University Japan Hospital
kn-affil=
affil-num=3
en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital
kn-affil=
affil-num=4
en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital
kn-affil=
affil-num=5
en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital
kn-affil=
affil-num=6
en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital
kn-affil=
affil-num=7
en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital
kn-affil=
affil-num=8
en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital
kn-affil=
affil-num=9
en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital
kn-affil=
affil-num=10
en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital
kn-affil=
affil-num=11
en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital
kn-affil=
affil-num=12
en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital
kn-affil=
affil-num=13
en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital
kn-affil=
affil-num=14
en-affil=Department of Hematology, Oncology, Respiratory, and Allergy Medicine, Okayama University Japan Hospital
kn-affil=
affil-num=15
en-affil=Department of Pathological diagnosis, Okayama University Japan Hospital
kn-affil=
affil-num=16
en-affil=Department of Breast and Endocrine surgery in Okayama University Japan Hospital
kn-affil=
en-keyword=Radiation-induced angiosarcoma
kn-keyword=Radiation-induced angiosarcoma
en-keyword=Radiotherapy
kn-keyword=Radiotherapy
en-keyword=Breast-conserving surgery
kn-keyword=Breast-conserving surgery
en-keyword=Breast cancer
kn-keyword=Breast cancer
en-keyword=Paclitaxel therapy
kn-keyword=Paclitaxel therapy
en-keyword=Adjuvant therapy of angiosarcoma
kn-keyword=Adjuvant therapy of angiosarcoma
END
start-ver=1.4
cd-journal=joma
no-vol=8
cd-vols=
no-issue=4
article-no=
start-page=509
end-page=518
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20191204
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Effects of loading contact on electric-power generation of lead zirconate titanate piezoelectric ceramic plate
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=To better understand the generation of electric power for piezoelectric PbZrTiO3 (PZT) ceramic plate (phi 25 mm), an attempt was made to investigate experimentally and numerically electric-power generation characteristics during cyclic bending under various loading fixtures (phi 0-phi 20 mm), i.e., different contact areas. Increasing the load-contact area on the PZT ceramic leads to a nonlinear decrease in the generated voltage. Decreasing contact area basically enhances the generated voltage, although the voltage saturates during loading when the contact area is less than phi 5 mm. A similar voltage is generated for phi 0 and phi 5 mm, which is attributed to strain status (ratio of compressive and tensile strain) and material failure due to different stress distribution in the PZT ceramic. On the basis of the obtained electric generation voltage, suitable loading conditions are clarified by loading with the phi 5 mm fixture, which generates a higher voltage and a longer lifetime of the PZT ceramic. From this approach, it is appeared that the area contact with the area ratio of 0.04 (phi 5 mm/phi 20 mm) is suitable to obtain the high efficiency of the electric voltage.
en-copyright=
kn-copyright=
en-aut-name=OkayasuMitsuhiro
en-aut-sei=Okayasu
en-aut-mei=Mitsuhiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=OgawaTsukasa
en-aut-sei=Ogawa
en-aut-mei=Tsukasa
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
affil-num=1
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=
affil-num=2
en-affil=Graduate School of Natural Science and Technology, Okayama University
kn-affil=
en-keyword=piezoelectric ceramic
kn-keyword=piezoelectric ceramic
en-keyword=lead zirconate titanate ceramic
kn-keyword=lead zirconate titanate ceramic
en-keyword=electric power generation
kn-keyword=electric power generation
END