ID | 48272 |
フルテキストURL | |
著者 |
Ghosh, S
Department of Hygiene, Sapporo Medical University School of Medicine, S 1,W 17, Chuo-Ku, Sapporo
Kobayashi, N
Department of Hygiene, Sapporo Medical University School of Medicine, S 1,W 17, Chuo-Ku, Sapporo
Nagashima, S
Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine
Chawla-Sarkar, M
Division of Virology, National Institute of Cholera and Enteric Diseases
Krishnan, T
Division of Virology, National Institute of Cholera and Enteric Diseases
Ganesh, B
Division of Virology, National Institute of Cholera and Enteric Diseases
Naik, TN
School of Biology, National Institute of Science Education and Research
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抄録 | Studies on bovine group B rotaviruses (GBRs) are limited. To date, only the VP6 gene of a single bovine GBR strain and the VP7 and NSP5 genes of a few bovine GBR strains have been sequenced and analyzed. In the present study, using a single-primer amplification method, we have determined the full-length nucleotide sequences of the VP1, VP2, VP4, VP6, NSP1 and NSP2 genes of three bovine GBR strains from eastern India. In all six of these genes, the bovine GBR strains shared high genetic relatedness among themselves but exhibited high genetic diversity with cognate genes of human, murine and ovine GBRs. Interestingly, as with group A rotaviruses, the bovine GBR VP1, VP2, VP6 and NSP2 genes appeared to be more conserved than the VP4 and NSP1 genes among strains of different species. The present study provides important insights into the genetic makeup and diversity of bovine GBRs, and also identifies a novel GBR VP4 genotype.
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発行日 | 2009-11-21
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出版物タイトル |
Archives of Virology
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巻 | 155巻
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号 | 2号
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出版者 | Springer
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開始ページ | 159
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終了ページ | 167
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ISSN | 0304-8608
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NCID | AA00548901
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資料タイプ |
学術雑誌論文
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プロジェクト |
インド感染症共同研究
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オフィシャル URL | http://www.springerlink.com/content/f24n7361k1370257/
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言語 |
英語
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著作権者 | © Springer-Verlag 2009
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論文のバージョン | author
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査読 |
有り
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DOI | |
PubMed ID | |
Web of Science KeyUT |