ID | 62311 |
フルテキストURL | |
著者 |
Selvam, Karthik Paneer
Graduate School of Natural Science and Technology, Okayama University
Nagahata, Taichi
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
Kato, Kosuke
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
Koreishi, Mayuko
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
Nakamura, Toshiyuki
Graduate School of Environmental and Life Science, Okayama University
Nakamura, Yoshimasa
Graduate School of Environmental and Life Science, Okayama University
ORCID
Kaken ID
publons
researchmap
Nishikawa, Takeshi
Graduate School of Natural Science and Technology, Okayama University
Kaken ID
publons
researchmap
Satoh, Ayano
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
ORCID
Kaken ID
publons
researchmap
Hayashi, Yasuhiko
Graduate School of Natural Science and Technology, Okayama University
ORCID
Kaken ID
researchmap
|
抄録 | Background
Conductive sheets of cellulose and carbon nanomaterials and its human skin applications are an interesting research aspect as they have potential for applications for skin compatibility. Hence it is needed to explore the effects and shed light on these applications. Method To fabricate wearable, portable, flexible, lightweight, inexpensive, and biocompatible composite materials, carbon nanohorns (CNHs) and hydroxyethylcellulose (HEC) were used as precursors to prepare CNH-HEC (Cnh-cel) composite sheets. Cnh-cel sheets were prepared with different loading concentrations of CNHs (10, 20 50,100mg) in 200mg cellulose. To fabricate the bio-compatible sheets, a pristine composite of CNHs and HEC was prepared without any pretreatment of the materials. Results The obtained sheets possess a conductivity of 1.83x10(-10)S/m and bio-compatible with human skin. Analysis for skin-compatibility was performed for Cnh-cel sheets by h-CLAT in vitro skin sensitization tests to evaluate the activation of THP-1 cells. It was found that THP-1 cells were not activated by Cnh-cel; hence Cnh-cel is a safe biomaterial for human skin. It was also found that the composite allowed only a maximum loading of 100mg to retain the consistent geometry of free-standing sheets of <100 Conclusion It can be concluded that cellulose and CNHs sheets are conductive and compatible to human skin applications. |
キーワード | Carbon Nanohorns
Cellulose
Skin sensitization
Composites
Bio-compatible
|
発行日 | 2021-10-23
|
出版物タイトル |
Biomaterials Research
|
巻 | 24巻
|
号 | 1号
|
出版者 | Springer Nature
|
開始ページ | 18
|
ISSN | 1226-4601
|
資料タイプ |
学術雑誌論文
|
言語 |
英語
|
OAI-PMH Set |
岡山大学
|
著作権者 | © The Author(s). 2020
|
論文のバージョン | publisher
|
PubMed ID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.1186/s40824-020-00194-3
|
ライセンス | http://creativecommons.org/licenses/by/4.0/
|
助成機関名 |
Okayama Prefecture Industrial promotion grant "Toku-den"
Japan Society for the Promotion of Science
|
助成番号 | 18 K06133
17H03818
|