ID | 56312 |
フルテキストURL | |
著者 |
Nishimura, Noriyuki
Radiation Breeding Division, Institute of Crop Science, National Agriculture and Food Research Organization
Tsuchiya, Wataru
Structural Biology Team, Advanced Analysis Center, National Agriculture and Food Research Organization
Moresco, James J.
Department of Molecular Medicine, The Scripps Research Institute
Hayashi, Yuki
Division of Biological Science, Graduate School of Science, Nagoya University
Satoh, Kouji
Radiation Breeding Division, Institute of Crop Science, National Agriculture and Food Research Organization
Kaiwa, Nahomi
Radiation Breeding Division, Institute of Crop Science, National Agriculture and Food Research Organization
Irisa, Tomoko
Radiation Breeding Division, Institute of Crop Science, National Agriculture and Food Research Organization
Kinoshita, Toshinori
Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University
Schroeder, Julian I.
Division of Biological Sciences, Cell and Developmental Biology Section, University of California
Yates III, John R.
Department of Molecular Medicine, The Scripps Research Institute
Hirayama, Takashi
Institute of Plant Science and Resources, Okayama University
Yamazaki, Toshimasa
Structural Biology Team, Advanced Analysis Center, National Agriculture and Food Research Organization
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抄録 | Abscisic acid (ABA) regulates abiotic stress and developmental responses including regulation of seed dormancy to prevent seeds from germinating under unfavorable environmental conditions. ABA HYPERSENSITIVE GERMINATION1 (AHG1) encoding a type 2C protein phosphatase (PP2C) is a central negative regulator of ABA response in germination; however, the molecular function and regulation of AHG1 remain elusive. Here we report that AHG1 interacts with DELAY OF GERMINATION1 (DOG1), which is a pivotal positive regulator in seed dormancy. DOG1 acts upstream of AHG1 and impairs the PP2C activity of AHG1 in vitro. Furthermore, DOG1 has the ability to bind heme. Binding of DOG1 to AHG1 and heme are independent processes, but both are essential for DOG1 function in vivo. Our study demonstrates that AHG1 and DOG1 constitute an important regulatory system for seed dormancy and germination by integrating multiple environmental signals, in parallel with the PYL/RCAR ABA receptor-mediated regulatory system.
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発行日 | 2018-06-06
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出版物タイトル |
Nature Communications
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巻 | 9巻
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出版者 | Springer Nature
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開始ページ | 2132
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ISSN | 2041-1723
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NCID | AA12645905
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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論文のバージョン | publisher
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PubMed ID | |
DOI | |
関連URL | isVersionOf https://doi.org/10.1038/s41467-018-04437-9
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