SoftMatter_7_fulltext.pdf 2.55 MB
Watanabe, Takaichi Department of Material and Energy Science, Graduate School of Environmental Science, Okayama University ORCID Kaken ID researchmap
Ono, Tsutomu Department of Material and Energy Science, Graduate School of Environmental Science, Okayama University ORCID Kaken ID publons researchmap
Monodisperse polylactide (PLA) microspheres were continuously fabricated by microfluidic emulsification and subsequent dilution in water. The diameter was precisely tuned from 6 to 50 μm by changing the flow rate of the fluids in microfluidics or the PLA concentration in the dispersed phase. The use of amphiphilic oil-soluble poly(ethylene glycol)-b-polylactide (o-PEG–PLA) as a matrix resulted in a highly porous microsphere morphology, and the porosity was controlled by blending PLA. Therefore, monodisperse PLA microspheres with the predetermined surface porosity were continuously produced by just enough reagents and energy.
Royal Society of Chemistry
|Web of Science KeyUT|