ID | 56937 |
JaLCDOI | |
フルテキストURL | |
著者 |
Isozaki, Hiroshi
Department of Surgery, Oomoto Hospital
Yamamoto, Yasuhisa
Department of Surgery, Oomoto Hospital
Murakami, Shigeki
Department of Surgery, Oomoto Hospital
Matsumoto, Sasau
Department of Surgery, Oomoto Hospital
Takama, Takehiro
Department of Surgery, Oomoto Hospital
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抄録 | To clarify the surgical outcomes of breast cancer patients with a preoperative diagnosis of ductal carcinoma in situ (DCIS) by core needle biopsy (CNB) (abbreviated as CNBDCIS), we retrospectively analyzed the cases of 131 patients with CNBDCIS who underwent surgery at Oomoto Hospital (32 total mastectomies, 99 conservative mastectomies). Our analysis of underestimation and predictors of invasive breast cancer of CNBDCIS revealed that the underestimation rate of CNBDCIS was 40.5% (53/131). A logistic regression analysis revealed that palpable tumors (yes to no, odds ratio [OR] 3.25), mammography (MMG) category group (category 4 or 5 to categories 1 , 2, or 3, OR 4.69) and MMG microcalcifications (no to yes, OR 0.24) were significant predictive factors for CNBDCIS invasion. In our analysis of the predictors of positive margins during CNBDCIS surgery, 36 (27.5%) of the 131 patients had positive margins after postoperative pathological examination. A logistic regression analysis revealed that the operative procedure (conservative surgery to total mastectomy, OR 21.4) and MMG microcalcifications (yes to no, OR 3.35) were significant factors related to positive margins during CNBDCIS surgery. Thus, MMG microcalcifications are a negative predictor of upgrading of CNBDCIS and a positive predictor of positive surgical margins for CNBDCIS.
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キーワード | ductal carcinoma in situ
core needle biopsy
underestimation
positive margins
microcalcifications on mammography
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Amo Type | Original Article
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出版物タイトル |
Acta Medica Okayama
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発行日 | 2019-08
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巻 | 73巻
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号 | 4号
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出版者 | Okayama University Medical School
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開始ページ | 349
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終了ページ | 356
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ISSN | 0386-300X
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NCID | AA00508441
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資料タイプ |
学術雑誌論文
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言語 |
英語
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著作権者 | CopyrightⒸ 2019 by Okayama University Medical School
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論文のバージョン | publisher
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査読 |
有り
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PubMed ID |