ID | 55311 |
JaLCDOI | |
フルテキストURL | |
著者 |
Yamazaki, Kenji
Department of Epidemiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Wakabayashi, Hiroshi
Department of Rheumatology, Okayama City Hospital
Suganami, Yu
Department of General Internal medicine, Okayama City Hospital
Sano, Shinichi
Department of General Internal medicine, Okayama City Hospital
Wakunami, Yu
Department of General Internal medicine, Okayama City Hospital
Katayama, Takashi
Department of General Internal medicine, Okayama City Hospital
Deguchi, Kentaro
Department of Neurology, Okayama City Hospital
Nagotani, Shoko
Department of Neurology, Okayama City Hospital
Kishida, Masayuki
|
抄録 | We report a case of a woman with typical dermatomyositis (DM) with skin manifestations, severe myalgia and muscle weakness complicated by interstitial lung disease (ILD) and pneumomediastinum. Pneumomediastinum persisted despite treatment with immunosuppressive therapy (steroids and cyclosporine). After the test for anti-melanoma differentiation-associated gene 5 (MDA5) antibody came out positive, we doubled the cyclosporine dose and her condition improved. Despite typical clinical features of DM, in cases complicated by pneumomediastinum or steroid resistance, measurement of anti-MDA5 antibody may be useful for immunosuppressant dose titration.
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キーワード | dermatomyositis
anti-melanoma differentiation-associated gene 5 antibody
interstitial lung disease
pneumomediastinum
|
Amo Type | Case Report
|
出版物タイトル |
Acta Medica Okayama
|
発行日 | 2017-08
|
巻 | 71巻
|
号 | 4号
|
出版者 | Okayama University Medical School
|
開始ページ | 341
|
終了ページ | 344
|
ISSN | 0386-300X
|
NCID | AA00508441
|
資料タイプ |
学術雑誌論文
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言語 |
英語
|
著作権者 | CopyrightⒸ 2017 by Okayama University Medical School
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論文のバージョン | publisher
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査読 |
有り
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PubMed ID |