ID | 58273 |
JaLCDOI | |
フルテキストURL | |
著者 |
Otsuki, Hideo
Department of Urology, Abiko Toho Hospital
Yamasaki, Tomoya
Department of Urology, Abiko Toho Hospital
Hori, Shunsuke
Department of Urology, Abiko Toho Hospital
Aoki, Hiroshi
Department of Urology, Abiko Toho Hospital
Kosaka, Takeo
Department of Urology, Keio University
Uehara, Shinya
Department of Urology, Kawasaki Medical School General Medical Center
Fujio, Kei
Department of Urology, Abiko Toho Hospital
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抄録 | To investigate the efficacy of mirabegron for lower urinary tract symptoms in patients with an indwelling ureteral stent after ureterorenoscopic lithotripsy. This was a prospective follow-up study of 76 patients with stent-related symptoms (SRSs). Patients with upper urinary calculi who were pre-stented for > 2 weeks before lithotripsy were examined for the presence of SRSs by tests including the International Prostate Symptom Score (IPSS), OAB Symptom Score (OABSS), and urinary bother and pain measured by a Visual Analogue Scale (VAS) before lithotripsy. Mirabegron (50 mg/day) was prescribed post-lithotripsy for 2 weeks. SRSs were assessed at the time of stent removal. The IPSS scores improved significantly from 16.2 to 14.3 (p<0.001) and the IPSS-QoL scores decreased significantly from 5.0 to 4.6 (p=0.012). The OABSS scores improved significantly from 7.7 to 6.8 (p=0.006), and the urinary urgency scores (OABSS-Q3) decreased significantly from 3.24 to 2.68 (p<0.001). The number of nocturia episodes decreased significantly from 2.5 to 2.2 (p=0.045). Urinary bother and pain assessed by the VAS declined from 4.2 and 3.1 to 3.8 (p=0.15) and 2.5 (p=0.075), respectively. Mirabegron significantly improved SRSs and the number of nocturia episodes due to a ureteral stent.
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キーワード | stent-related symptoms
overactive bladder
mirabegron
ureterorenoscopic lithotripsy
ureteral stent
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Amo Type | Original Article
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出版物タイトル |
Acta Medica Okayama
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発行日 | 2020-04
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巻 | 74巻
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号 | 2号
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出版者 | Okayama University Medical School
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開始ページ | 145
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終了ページ | 150
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ISSN | 0386-300X
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NCID | AA00508441
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資料タイプ |
学術雑誌論文
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言語 |
英語
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著作権者 | CopyrightⒸ 2020 by Okayama University Medical School
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論文のバージョン | publisher
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査読 |
有り
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PubMed ID | |
Web of Science KeyUT | |
NAID |