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ID 58272
JaLCDOI
フルテキストURL
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著者
Isozaki, Hiroshi Department of Surgery, Oomoto Hospital
Yamamoto, Yasuhisa Department of Surgery, Oomoto Hospital
Sakai, Kunihiko Department of Surgery, Oomoto Hospital
Sho, Tatuo Department of Surgery, Oomoto Hospital
Ishihara, Kiyohiro Department of Surgery, Oomoto Hospital
Murakami, Shigeki Department of Surgery, Oomoto Hospital
Matsumoto, Sasau Department of Surgery, Oomoto Hospital
Takama, Takehiro Department of Surgery, Oomoto Hospital
抄録
Mucinous carcinoma (MC) of the breast is a rare and special type of malignancy, with a substantial amount of extracellular mucin. We compared the clinicopathological features and the long-term survival of MC patients with those of invasive ductal carcinoma-no special type (IDC-NST) patients, and we examined prognostic factors of MC. A total of 116 patients with mucinous carcinoma and 3,258 patients with IDC-NST who underwent surgery at our hospital (1977-2008) were enrolled. The 10-year overall survival rate and breast cancer-specific survival rate (BSS) of the MC patients (88.3%, 93.7%) were both significantly higher than those of IDC-NST patients (81.6%, 85.0%) (p=0.015, p=0.005, respectively). A Cox regression analysis demonstrated that MC tended to be an independent prognostic factor (hazard ratio 0.44, p=0.098). The BSS of the MC patients with positive lymph node (LN) metastasis was significantly poorer than that of the patients without it, by univariate analysis (p=0.002). The tumor size in the MC patients with positive LN metastasis (mean 3.2 cm) was significantly larger than that in the patients without it (mean 1.9 cm) (p=0.0004). Although a Cox regression analysis revealed no independent factor, MC patients with positive LN metastasis should be treated for advanced invasive ductal breast cancer.
キーワード
breast cancer
mucinous carcinoma
clinicopathological features
long-term prognosis
Amo Type
Original Article
発行日
2020-04
出版物タイトル
Acta Medica Okayama
74巻
2号
出版者
Okayama University Medical School
開始ページ
137
終了ページ
143
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
著作権者
CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Science KeyUT