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ID 53646
フルテキストURL
著者
Tsuda, Toshihide Graduate School of Environmental and Life Science, Okayama University
Tokinobu, Akiko Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Yamamoto, Eiji Faculty of Informatics, Okayama University of Science
Suzuki, Etsuji Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
抄録
Background: After the Great East Japan Earthquake and Tsunami in March 2011, radioactive elements were released from the Fukushima Daiichi Nuclear Power Plant. Based on prior knowledge, concern emerged about whether an increased incidence of thyroid cancer among exposed residents would occur as a result. Methods: After the release, Fukushima Prefecture performed ultrasound thyroid screening on all residents ages <=18 years. The first round of screening included 298,577 examinees, and a second round began in April 2014. We analyzed the prefecture results from the first and second round up to December 31, 2014, in comparison with the Japanese annual incidence and the incidence within a reference area in Fukushima Prefecture. Results: The highest incidence rate ratio, using a latency period of 4 years, was observed in the central middle district of the prefecture compared with the Japanese annual incidence (incidence rate ratio = 50; 95% confidence interval [CI] = 25, 90). The prevalence of thyroid cancer was 605 per million examinees (95% CI = 302, 1,082) and the prevalence odds ratio compared with the reference district in Fukushima Prefecture was 2.6 (95% CI = 0.99, 7.0). In the second screening round, even under the assumption that the rest of examinees were disease free, an incidence rate ratio of 12 has already been observed (95% CI = 5.1, 23). Conclusions: An excess of thyroid cancer has been detected by ultrasound among children and adolescents in Fukushima Prefecture within 4 years of the release, and is unlikely to be explained by a screening surge.
備考
This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.
発行日
2015
出版物タイトル
Epidemiology
出版者
International Society for Environmental Epidemiology
ISSN
1044-3983
NCID
AA10832184
資料タイプ
学術雑誌論文
オフィシャル URL
http://dx.doi.org/10.1097/EDE.0000000000000385
言語
English
著作権者
Copyright (C) 2015 Wolters Kluwer Health
論文のバージョン
publisher
査読
有り
DOI
PubMed ID