start-ver=1.4 cd-journal=joma no-vol=34 cd-vols= no-issue=4 article-no= start-page=845 end-page=848 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=200805 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Improvement of piezoresistance properties of silicon carbide ceramics through co-doping of aluminum nitride and nitrogen en-subtitle= kn-subtitle= en-abstract= kn-abstract=The piezoresistance coefficient was measured on co-doped silicon carbide ceramics. Evaluation samples of alpha-silicon carbide ceramics were first fabricated by glass capsule HIP method using powder mixture of silicon carbide and aluminum nitride with various ratios. The resultant aluminum nitride added silicon carbide ceramics were doped with nitrogen by changing the post-HIP nitrogen gas pressure. The lattice parameter increased with the amount of adding aluminum nitride indicating that the incorporated aluminum substituted smaller silicon atoms. After post-HIP treatment, lattice parameter then decreased with nitrogen gas pressure. The piezoresistive coefficient increased with the addition of aluminum nitride, it further increased with the nitrogen doping pressure. en-copyright= kn-copyright= en-aut-name=KishimotoAkira en-aut-sei=Kishimoto en-aut-mei=Akira kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OkadaYasuyuki en-aut-sei=Okada en-aut-mei=Yasuyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HayashiHidetaka en-aut-sei=Hayashi en-aut-mei=Hidetaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University affil-num=2 en-affil= kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University affil-num=3 en-affil= kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University en-keyword=HIP kn-keyword=HIP en-keyword=co-doping kn-keyword=co-doping en-keyword=donor kn-keyword=donor en-keyword=acceptor kn-keyword=acceptor en-keyword=silicon carbide kn-keyword=silicon carbide en-keyword=strain sensor kn-keyword=strain sensor END start-ver=1.4 cd-journal=joma no-vol=38 cd-vols= no-issue=9 article-no= start-page=1751 end-page=1759 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=200509 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Flow-induced hardening of endothelial nucleus as an intracellular stress-bearing organelle en-subtitle= kn-subtitle= en-abstract= kn-abstract=The mechanical contribution of nucleus in adherent cells to bearing intracellular stresses remains unclear. In this paper, the effects of fluid shear stress on morphology and elastic properties of endothelial nuclei were investigated. The morphological observation suggested that the nuclei in the cytoplasm were being vertically compressed under static conditions, whereas they were elongated and more compressed with a fluid shear stress of 2 Pa (20 dyn/cm(2)) onto the cell. The elongated nuclei remained the shape even after they were isolated from the cells. The micropipette aspiration technique on the isolated nuclei revealed that the elastic modulus of elongated nuclei, 0.62 +/- 0.15 kPa (n = 13, mean +/- SD), was significantly higher than that of control nuclei, 0.42 +/- 0.12 kPa (n = 11), suggesting that the nuclei remodeled their structure due to the shear stress. Based of these results and a transmission electron microscopy, a possibility of the nucleus as an intracellular compression-bearing organelle was proposed, which will impact interpretation of stress distribution in adherent cells. (C) 2005 Elsevier Ltd. All rights reserved. en-copyright= kn-copyright= en-aut-name=DeguchiShinji en-aut-sei=Deguchi en-aut-mei=Shinji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MaedaKenjiro en-aut-sei=Maeda en-aut-mei=Kenjiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OhashiToshiro en-aut-sei=Ohashi en-aut-mei=Toshiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SatoMasaaki en-aut-sei=Sato en-aut-mei=Masaaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Department of Energy Systems Engineering, Graduate School of Natural Science and Technology, Okayama University affil-num=2 en-affil= kn-affil=Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University affil-num=3 en-affil= kn-affil=Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University affil-num=4 en-affil= kn-affil=Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University en-keyword=cell mechanics kn-keyword=cell mechanics en-keyword=nucleus kn-keyword=nucleus en-keyword=mechanical properties kn-keyword=mechanical properties en-keyword=shear stress kn-keyword=shear stress en-keyword=mechanotransduction kn-keyword=mechanotransduction en-keyword=atomic-force microscopy kn-keyword=atomic-force microscopy en-keyword=shear-stress kn-keyword=shear-stress en-keyword=mechanical-properties kn-keyword=mechanical-properties en-keyword=viscoelastic kn-keyword=viscoelastic en-keyword=properties kn-keyword=properties en-keyword=cells kn-keyword=cells END