ID | 32940 |
フルテキストURL | |
著者 |
Uchida, Naohiko
Department of Neuropsychiatry, Okayama University Graduate School of Medicine and Dentistry
Ujike, Hiroshi
Department of Neuropsychiatry, Okayama University Graduate School of Medicine and Dentistry
Nakata, Kenji
Department of Neuropsychiatry, Okayama University Graduate School of Medicine and Dentistry
Takaki, Manabu
Department of Neuropsychiatry, Okayama University Graduate School of Medicine and Dentistry
Kaken ID
publons
researchmap
Nomura, Akira
Department of Neuropsychiatry, Okayama University Graduate School of Medicine and Dentistry
Katsu, Takeshi
Department of Neuropsychiatry, Okayama University Graduate School of Medicine and Dentistry
Tanaka, Yuji
Department of Neuropsychiatry, Okayama University Graduate School of Medicine and Dentistry
Imamura, Takaki
Department of Neuropsychiatry, Okayama University Graduate School of Medicine and Dentistry
Sakai, Ayumu
Department of Neuropsychiatry, Okayama University Graduate School of Medicine and Dentistry
Kuroda, Shigetoshi
Department of Neuropsychiatry, Okayama University Graduate School of Medicine and Dentistry
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抄録 | Background: Several lines of evidence have supported possible roles of the sigma receptors in the etiology of schizophrenia and mechanisms of antipsychotic efficacy. An association study provided genetic evidence that the sigma receptor type 1 gene (SIGMAR1) was a possible susceptibility factor for schizophrenia, however, it was not replicated by a subsequent study. It is necessary to evaluate further the possibility that the SIGMAR1 gene is associated with susceptibility to schizophrenia.
Methods: A case-control association study between two polymorphisms of the SIGMAR1 gene, G-241T/C-240T and Gln2Pro, and schizophrenia in Japanese population, and meta-analysis including present and previous studies. |
備考 | Digital Object Identifier: 10.1186/1471-244X-3-13
Published with permission from the copyright holder. This is the institute's copy, as published in BMC Psychiatry, 21 October 2003, 3:13. Publisher URL:http://dx.doi.org/10.1186/1471-244X-3-13 Copyright © 2003 Uchida et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL. |
発行日 | 2003-10-21
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出版物タイトル |
BMC Psychiatry
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巻 | 3巻
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出版者 | BioMed Central
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NCID | AA12072671
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資料タイプ |
学術雑誌論文
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言語 |
英語
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著作権者 | Uchida et al; licensee BioMed Central Ltd.
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論文のバージョン | publisher
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査読 |
有り
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DOI | |
PubMed ID | |
Submission Path | internal_medicine/3
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