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ID 55376
フルテキストURL
著者
Morimoto, Naoki Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Div Pharmaceut Sci
Morioku, Kumika Okayama Univ, Fac Engn, Dept Appl Chem & Biotechnol
Suzuki, Hideyuki Okayama Univ, Res Core Interdisciplinary Sci
Takeuchi, Yasuo Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Div Pharmaceut Sci
Nishina, Yuta Okayama Univ, Res Core Interdisciplinary Sci
抄録
Indole readily undergoes nucleophilic substitution at the C3 site, and many indole derivatives have been functionalized using this property. Indole also forms indolium, which allows electrophilic addition in acidic conditions, but current examples have been limited to intramolecular reactions. C2 site-selective nucleophilic addition to indole derivatives using fluoroalcohol and a Lewis acid was developed.
備考
This is an Accepted Manuscript of an article published by American Chemical Society
発行日
2016-04-27
出版物タイトル
Organic Letters
18巻
9号
出版者
American Chemical Society
開始ページ
2020
終了ページ
2023
ISSN
1523-7060
NCID
AA11347843
資料タイプ
学術雑誌論文
言語
English
OAI-PMH Set
岡山大学
著作権者
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン
author
PubMed ID
DOI
Web of Sience KeyUT
関連URL
https://doi.org/10.1021/acs.orglett.6b00629