JaLCDOI | 10.18926/bgeou/52424 |
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タイトル(別表記) | Evoked potentials in patients with Angelman syndrome |
フルテキストURL | 108_0037_0040.pdf |
著者 | 眞田 敏| 小川 和則| 大守 伊織| 荻野 竜也| 石田 喬士| |
抄録 | Evoked potentials were studied in four cases with Angelman syndrome. Chromosome 15ql1-13 deletion was proved in two cases and paternal uniparental disomy was proved in the rest. Prolonged photo-evoked eyelid microvibration latencies were noted in all four, while visual evoked potential latencies remained within normal limits in three of four. Interpeak latencies of wave I to wave V in auditory brainstem response were prolonged in two of four. Short latency somatosensory evoked potential was examined in two cases and prolonged interpeak latency of wave P3 to wave N1 was noted in one case. Brink reflex was examined in one case and prolonged R2 latency was noted. These findings suggest that the brainstem is disturbed in cases with Angelman syndrome. |
キーワード | Angelman syndrome severely handicapped evoked potentials photic stimulation brink reflex |
出版物タイトル | 岡山大学教育学部研究集録 |
発行日 | 1998 |
巻 | 108巻 |
号 | 1号 |
開始ページ | 37 |
終了ページ | 40 |
ISSN | 0471-4008 |
言語 | 日本語 |
論文のバージョン | publisher |
NAID | 120005425642 |
JaLCDOI | 10.18926/AMO/30765 |
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フルテキストURL | fulltext.pdf |
著者 | Oka, Eiji| Sanada, Satoshi| Asano, Takashi| Ishida, Takashi| |
抄録 | Mental retardation is detected in 20-30% of children with epilepsy at hospitals specializing in treatment of childhood epilepsy. However, the incidence of mental deterioration in childhood epilepsy is not high. In this study, mental deterioration was found in 52 (1.8%) of the 2,880 children with epilepsy at Okayama University Hospital. The patients showing mental deterioration mostly suffered from specific epileptic syndromes, such as West syndrome, Lennox-Gastaut syndrome, severe myoclonic epilepsy in infancy and epilepsy with continuous spike-waves during slow wave sleep. These types of epilepsy show generalized electroencephalographic (EEG) abnormalities. It is presumed that mental deterioration is caused by the total effects of prolonged diffuse EEG abnormalities and the age of the patients. Antiepileptic drugs exert a relatively minor effect on mental deterioration. |
キーワード | mental deterioration mental retardation epilepsy EFG children |
Amo Type | Review |
出版物タイトル | Acta Medica Okayama |
発行日 | 1997-08 |
巻 | 51巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 173 |
終了ページ | 178 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 9284965 |
Web of Science KeyUT | A1997XU03200001 |
JaLCDOI | 10.18926/AMO/30779 |
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フルテキストURL | fulltext.pdf |
著者 | Sanada, Satoshi| Murakami, Nagako| Horiuchi, Isaac| Oka, Eiji| Ohtahara, Shunsuke| |
抄録 | Using a transcranial Doppler blood flowmeter, the blood flow velocity (BFV) ratio of the middle cerebral artery (MCA) to the basilar artery (BA) was investigated in 12 patients with severe motor and intellectual disability syndrome. The BFV of the MCA was also investigated in 58 handicapped children, classified according to the severity of their motor and intellectual disability. The ratio of the MCA to the BA was lower by 2 SD from the mean of our previously reported standard value in 8 out of the 12 cases with severe motor and intellectual disability syndrome, suggesting a more profound decrease in the level of brain activity in the MCA area than that of the BA area. The BFV of the MCA mainly decreased in cases belonging to the category of the most severe motor disability (bed-ridden). Hence, it is suggested that motor disability is the main factor related to the decrease in the BFV of the MCA. |
キーワード | transcranial blood flowmetry blood flow velocity handicapped children severe motor and intellectual disability syndrome |
Amo Type | Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 1997-04 |
巻 | 51巻 |
号 | 2号 |
出版者 | Okayama University Medical School |
開始ページ | 111 |
終了ページ | 113 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 9142349 |
Web of Science KeyUT | A1997WX19600009 |
著者 | 真田 敏| 岡 鍈次| 大田原 俊輔| 河原 道子| 栄 勝美| 平木 祥夫| |
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発行日 | 1997-02-28 |
出版物タイトル | 岡山医学会雑誌 |
巻 | 109巻 |
号 | 1-2号 |
資料タイプ | 学術雑誌論文 |