JaLCDOI 10.18926/AMO/64363
フルテキストURL 77_1_65.pdf
著者 Sato, Ken| Takigawa, Nagio| Kubo, Toshio| Katayama, Hideki| Kishino, Daizo| Okada, Toshiaki| Hisamoto, Akiko| Mimoto, Junko| Ochi, Nobuaki| Yoshino, Tadashi| Ueoka, Hiroshi| Tanimoto, Mitsune| Maeda, Yoshionobu| Kiura, Katsuyuki|
抄録 We investigated the effects of celecoxib combined with (−)-epigallocatechin-3-gallate (EGCG) or polyphenon E in a cisplatin-induced lung tumorigenesis model. Four-week-old female A/J mice were divided into seven groups: (i) Control, (ii) 150 mg/kg celecoxib (150Cel), (iii) 1,500 mg/kg celecoxib (1500Cel), (iv) EGCG+150 mg/kg celecoxib (EGCG+150Cel), (v) EGCG+1,500 mg/kg celecoxib (EGCG+1500Cel), (vi) polyphenon E+150 mg/kg celecoxib (PolyE+150Cel), and (vii) polyphenon E+1,500 mg/kg celecoxib (PolyE+1500Cel). All mice were administered cisplatin (1.62 mg/kg of body weight, i.p.) 1×/week for 10 weeks and sacrificed at week 30; the numbers of tumors on the lung surface were then determined. The tumor incidence and multiplicity (no. of tumors/mouse, mean±SD) were respectively 95% and 2.15±1.50 in Control, 95% and 2.10±1.29 in 150Cel, 86% and 1.67±1.20 in 1500Cel, 71% and 1.38±1.24 in EGCG+150Cel, 67% and 1.29±1.38 in EGCG+1500Cel, 80% and 1.95±1.36 in PolyE+150Cel, and 65% and 1.05±0.10 in PolyE+1500Cel. The combination of high-dose celecoxib with EGCG or polyphenon E significantly reduced multiplicity in cisplatin-induced lung tumors.
キーワード celecoxib cisplatin EGCG lung tumor polyphenon E
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-02
77巻
1号
出版者 Okayama University Medical School
開始ページ 65
終了ページ 70
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 36849147
Web of Science KeyUT 000952992100004
フルテキストURL fulltext.pdf
著者 Nishimura, Tomoka| Ichihara, Eiki| Yokoyama, Toshihide| Inoue, Koji| Tamura, Tomoki| Sato, Ken| Oda, Naohiro| Kano, Hirohisa| Kishino, Daizo| Kawai, Haruyuki| Inoue, Masaaki| Ochi, Nobuaki| Fujimoto, Nobukazu| Ichikawa, Hirohisa| Ando, Chihiro| Hotta, Katsuyuki| Maeda, Yoshinobu| Kiura, Katsuyuki|
キーワード pleural effusion non-small cell carcinoma immune checkpoint inhibitors
発行日 2022-12-14
出版物タイトル Cancers
14巻
24号
出版者 MDPI
開始ページ 6184
ISSN 2072-6694
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2022 by the authors.
論文のバージョン publisher
PubMed ID 36551668
DOI 10.3390/cancers14246184
Web of Science KeyUT 000900618600001
関連URL isVersionOf https://doi.org/10.3390/cancers14246184
フルテキストURL fulltext.pdf
著者 Bu-Omer, Hani M.| Gofuku, Akio| Sato, Kenji| Miyakoshi, Makoto|
キーワード sense of agency electroencephalography (EEG) mirror visual feedback virtual reality delayed visual feedback
発行日 2021-06-03
出版物タイトル Brain Sciences
11巻
6号
出版者 MDPI
開始ページ 743
ISSN 2076-3425
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 by the authors.
論文のバージョン publisher
PubMed ID 34205076
DOI 10.3390/brainsci11060743
Web of Science KeyUT 000665308500001
関連URL isVersionOf https://doi.org/10.3390/brainsci11060743
JaLCDOI 10.18926/AMO/53021
フルテキストURL 68_6_323.pdf
著者 Hirayama, Takahiro| Nagano, Osamu| Shiba, Naoki| Yumoto, Tetsuya| Sato, Keiji| Terado, Michihisa| Ugawa, Toyomu| Ichiba, Shingo| Ujike, Yoshihito|
抄録 In adult high-frequency oscillatory ventilation (HFOV), stroke volume (SV) and mean lung pressure (PLung) are important for lung protection. We measured the airway pressure at the Y-piece and the lung pressure during HFOV using a lung model and HFOV ventilators for adults (R100 and 3100B). The lung model was made of a 20-liter, airtight rigid plastic container (adiabatic compliance: 19.3ml/cmH2O) with or without a resistor (20cmH2O/l/sec). The ventilator settings were as follows: mean airway pressure (MAP), 30cmH2O;frequency, 5-15Hz (every 1Hz);airway pressure amplitude (AMP), maximum;and % of inspiratory time (IT), 50% for R100, 33% or 50% for 3100B. The measurements were also performed with an AMP of 2/3 or 1/3 maximum at 5, 10 and 15Hz. The PLung and the measured MAP were not consistently identical to the setting MAP in either ventilator, and decreasing IT decreased the PLung in 3100B. In conclusion, we must pay attention to the possible discrepancy between the PLung and the setting MAP during adult HFOV.
キーワード HFOV mean lung pressure mean airway pressure
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2014-12
68巻
6号
出版者 Okayama University Medical School
開始ページ 323
終了ページ 329
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25519026
Web of Science KeyUT 000346882200002
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/53132
JaLCDOI 10.18926/AMO/53027
フルテキストURL 68_6_375.pdf
著者 Yamanaka, Reiko| Soga, Yoshihiko| Moriya, Yoshie| Okui, Akemi| Takeuchi, Tetsuo| Sato, Kenji| Morimatsu, Hiroshi| Morita, Manabu|
抄録 We encountered a 74-year-old male patient with tongue laceration after convulsive seizures under intensive care. The tongue showed severe swelling, and the right ventral surface had been lacerated by his isolated and pointed right lower canine. Our university hospital has established a perioperative management center, and is promoting interprofessional collaboration, including dentists, in perioperative management. Dentists collaborating in the perioperative management center took dental impressions, with the support of anesthesiologists who opened the patientʼs jaw under propofol sedation, to produce a mouth protector. By raising the patientʼs bite, the completed mouth protector prevented the isolated tooth from contacting the tongue and protected the lacerated wound. Use of the mouth protector prevented the lacerated tongue from coming into contact with the pointed tooth, and the tongue healed gradually. These findings underscore that interprofessional collaboration including dentists can improve the quality of medical care.
キーワード mouth protector tongue laceration
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2014-12
68巻
6号
出版者 Okayama University Medical School
開始ページ 375
終了ページ 378
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25519032
Web of Science KeyUT 000346882200008
JaLCDOI 10.18926/AMO/53023
フルテキストURL 68_6_339.pdf
著者 Nishie, Hiroyuki| Mizobuchi, Satoshi| Suzuki, Etsuji| Sato, Kenji| Toda, Yuichiro| Matsuoka, Junji| Morimatsu, Hiroshi|
抄録 The main purpose of this study was to determine the relationships between Japanese individualsʼ interest in living wills and their preferred end-of-life care and death locations. Questionnaires were mailed to 1,000 individuals aged ァ50 to measure these 2 factors. We examined the associations between the respondentsʼ characteristics and their preferred care and death locations by using multinomial logistic regression models. The response rate was 74%. Home was the most frequently preferred place for end-of-life care (64%), and a palliative care unit (PCU) was the most commonly preferred place to die (51%). Living will interest was associated with a preference for care (odds ratio [OR] 4.74, 95% confidence interval [CI] 1.95-12.1) and death (OR 2.75, 95% CI 1.70-4.47) in a PCU rather than a hospital, but it was not associated with the choice between receiving care or dying at home instead of a hospital. We must consider why Japanese people think home death is impracticable. The Japanese palliative care system should be expanded to meet patientsʼ end-of-life needs, and this includes not only facilitating home care but also increasing access to PCU care.
キーワード advance healthcare directive living will end-of-life care palliative care unit place of death
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2014-12
68巻
6号
出版者 Okayama University Medical School
開始ページ 339
終了ページ 348
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25519028
Web of Science KeyUT 000346882200004
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/53134
著者 西江 宏行| 溝渕 知司| 松崎 孝| 三宅 麻子| 賀来 隆治| 石川 慎一| 佐藤 健治| 松三 昌樹| 森田 潔|
発行日 2007-05-01
出版物タイトル 岡山医学会雑誌
119巻
1号
資料タイプ 学術雑誌論文
著者 春木 直人| 稲葉 英男| 堀部 明彦| 田中 真司| 中田 達| 佐藤 健次|
発行日 2005-02
出版物タイトル 日本機械学會論文集 B編
71巻
702号
資料タイプ 学術雑誌論文
著者 稲葉 英男| 春木 直人| 中田 達| 堀部 明彦| 古本 直行| 佐藤 健次|
発行日 2002-02-25
出版物タイトル 日本機械学會論文集 B編
68巻
666号
資料タイプ 学術雑誌論文
著者 稲葉 英男| 佐藤 憲二|
発行日 1997-03-25
出版物タイトル 日本機械学會論文集 B編
63巻
607号
資料タイプ 学術雑誌論文
著者 稲葉 英男| 佐藤 憲二|
発行日 1997-03-25
出版物タイトル 日本機械学會論文集 B編
63巻
607号
資料タイプ 学術雑誌論文
著者 稲葉 英男| 佐藤 憲二|
発行日 1996-10-25
出版物タイトル 日本機械学會論文集 B編
62巻
602号
資料タイプ 学術雑誌論文
著者 稲葉 英男| 佐藤 憲二|
発行日 1996-01-25
出版物タイトル 日本機械学會論文集 B編
62巻
593号
資料タイプ 学術雑誌論文
著者 稲葉 英男| 佐藤 憲二|
発行日 1994-12-25
出版物タイトル 日本機械学會論文集 B編
60巻
580号
資料タイプ 学術雑誌論文
タイトル(別表記) 殺菌剤、ベノミル、チウラムの土壌微生物相と2~3の土壌生息性糸状菌に及ぼす影響
フルテキストURL 054_0001_0008.pdf
著者 奥 八郎| 沖 和生| 白石 友紀| 佐藤 健二| 大内 成志|
抄録 Effects of Benomyl and Thiram on the soil microflora and some soil inhabitant fungi were studied using the_ soil (sandy loam) of the experimental field, Okayama University. Under field conditions, heavy application of Benomyl did not affect significantly the soil microflora. Thiram, however, reduced the fungal population in soil to 1/6 at the next day of treatment, but recovered to the normal level after 6 days. Under laboratory conditions, both fungicides did not affect soil microflora. Population of Benomyl-to lerant fungi was about 1/10 of the total fungi and increased slightly in the field soil by treatment with Benomyl at the later stage of experiment during June to October. Neither Thiram-tolerant fungus nor bacterium was found in both Thiram-treated and non-treated soils. A fungus highly tolerant to Benomyl was isolated and identified as Aspergillus versicolor, and found to not have the metabolic activity to degrade BCM. The absorption of BCM by the mycelia of this tolerant fungus, A. versicolor, was less than half of the BCM-sensitive one, such as Cladosporium harbarum.
出版物タイトル 岡山大学農学部学術報告
発行日 1979
54巻
1号
開始ページ 1
終了ページ 8
ISSN 0474-0254
言語 英語
論文のバージョン publisher