start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=20050325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=2-または3-次元的有機-無機ハイブリッドの創成とバイオミネラリゼーションの誘起
kn-title=Synthesis of two- and three dimensional organic-inorganic hybrids for inducing biomineralization
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=ShirosakiYuki
en-aut-sei=Shirosaki
en-aut-mei=Yuki
kn-aut-name=城崎由紀
kn-aut-sei=城崎
kn-aut-mei=由紀
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END

start-ver=1.4
cd-journal=joma
no-vol=36
cd-vols=
no-issue=1
article-no=
start-page=117
end-page=121
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2001
dt-pub=200112
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Improvement of Biocompatibility of Silicone Elastomer by Surface Modification
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=γ-Methacryloxypropyltrimethoxysilane (γ-MPS) was grafted to silicone due to emulsion polymerization to induce Si-OH groups, in order to provide silicone with bioactivity spontaneous deposition of apatite in body fluid and to improve cytocompatibility. Apatite deposited on the grafted silicone within 7 days of soaking in 1.5 times as concentrated as the Kokubo solution. Osteoblastic cells (MC3T3-E1) were cultured on the specimens up to 7 days. After 5 days of culture, the number of MC3T3-E1 cells on the grafted specimen was much greater than that on the original specimen. These results indicated that the biocompatibility of silicone elastomer was improved by the grafting γ-MPS.
en-copyright=
kn-copyright=

en-aut-name=ShirosakiYuki
en-aut-sei=Shirosaki
en-aut-mei=Yuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=TsuruKanji
en-aut-sei=Tsuru
en-aut-mei=Kanji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=HayakawaSatoshi
en-aut-sei=Hayakawa
en-aut-mei=Satoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=OsakaAkiyoshi
en-aut-sei=Osaka
en-aut-mei=Akiyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=TakashimaSeisuke
en-aut-sei=Takashima
en-aut-mei=Seisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University

affil-num=2
en-affil=
kn-affil=Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University

affil-num=3
en-affil=
kn-affil=Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University

affil-num=4
en-affil=
kn-affil=Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University

affil-num=5
en-affil=
kn-affil=Co-operative Research Center, Okayama University
END

start-ver=1.4
cd-journal=joma
no-vol=34
cd-vols=
no-issue=1-2
article-no=
start-page=39
end-page=43
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2000
dt-pub=20000327
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Cytocompatibility of Silicone Elastomer Treated with Hydrogenperoxide Containing Tantalum Chloride
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Silicone elastomer was chemically treated at 60℃ for 7 days with 30 wt% H(2)O(2) solutions with or without TaCl(5) and soaked for various periods in a simulated body
fluid(Kokubo solution) up to 21 days. Apatite formation ability of the surface of the silicone elastomer specimens was investigated with thin-film X-ray diffraction and FT-IR
reflection spectroscopy. These silicone specimens did not deposit apatite or calcium phosphates, irrespective of chemical treatment. Osteoblast-like cells (MC3T3-El) derived from mouse were cultured on the specimens at 36.5℃ under 5%C0(2) and 95% humidity. Similar degree of proliferation of cells was observed at 7 days among three specimens, while the no treatment specimen after incubation for 5 days showed a lower degree of proliferation than the silicone treated with 30 wt% H(2)O(2) solutions with or without TaCl(5). Alkaline phosphatase activity of the cells proliferated on the no treatment specimen was lower than those of the silicone treated with 30 wt% H(2)O(2) solutions with or without
TaCl(5). These results indicate that the cytotoxicity of the silicone could be improved by the chemical treatment with 30 wt% H(2)O(2) solutions with or without TaCl(5).
en-copyright=
kn-copyright=

en-aut-name=HayakawaSatoshi
en-aut-sei=Hayakawa
en-aut-mei=Satoshi
kn-aut-name=早川聡
kn-aut-sei=早川
kn-aut-mei=聡
aut-affil-num=1
ORCID=

en-aut-name=ShirosakiYuki
en-aut-sei=Shirosaki
en-aut-mei=Yuki
kn-aut-name=城崎由紀
kn-aut-sei=城崎
kn-aut-mei=由紀
aut-affil-num=2
ORCID=

en-aut-name=YabutaTakeshi
en-aut-sei=Yabuta
en-aut-mei=Takeshi
kn-aut-name=籔田武司
kn-aut-sei=籔田
kn-aut-mei=武司
aut-affil-num=3
ORCID=

en-aut-name=TsuruKanji
en-aut-sei=Tsuru
en-aut-mei=Kanji
kn-aut-name=都留寛治
kn-aut-sei=都留
kn-aut-mei=寛治
aut-affil-num=4
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=OhtsukiChikara
kn-aut-sei=Ohtsuki
kn-aut-mei=Chikara
aut-affil-num=5
ORCID=

en-aut-name=OsakaAkiyoshi
en-aut-sei=Osaka
en-aut-mei=Akiyoshi
kn-aut-name=尾坂明義
kn-aut-sei=尾坂
kn-aut-mei=明義
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Bioscience and Biotechnology

affil-num=2
en-affil=
kn-affil=Department of Bioscience and Biotechnology

affil-num=3
en-affil=
kn-affil=Department of Bioscience and Biotechnology

affil-num=4
en-affil=
kn-affil=Department of Bioscience and Biotechnology

affil-num=5
en-affil=
kn-affil=Graduate School of Materials Science. Nara Institute of Science and Technology

affil-num=6
en-affil=
kn-affil=Department of Bioscience and Biotechnology
END