フルテキストURL fulltext.pdf
著者 Ono, Kisho| Yoshioka, Norie| Masui, Masanori| Obata, Kyoichi| Kunisada, Yuki| Okui, Tatsuo| Ibaragi, Soichiro| Kawai, Hotaka| Nagatsuka, Hitoshi| Sasaki, Akira|
キーワード delayed metastasis lymphatic regurgitation neck dissection occipital lymph node oral cancer
発行日 2020-07-30
出版物タイトル Clinical Case Reports
出版者 Wiley
ISSN 2050-0904
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © 2020 The Authors.
論文のバージョン publisher
DOI 10.1002/ccr3.3086
Web of Science KeyUT 000553667700001
関連URL isVersionOf https://doi.org/10.1002/ccr3.3086
JaLCDOI 10.18926/AMO/54506
フルテキストURL 70_4_291.pdf
著者 Yoshioka, Norie| Shimo, Tsuyoshi| Ibaragi, Soichiro| Sasaki, Akira|
抄録 Temporomandibular joint (TMJ) dislocation can occur during daily activities and negatively affect a patientʼs quality of life. Although both nonsurgical and surgical techniques have been used to treat recurrent TMJ dislocation, the former is not always successful and the latter, although having a high success rate, is invasive and requires hospitalization. Recently, autologous blood injection has been used to treat recurrent TMJ dislocation. However, this technique is not yet widely used in clinical practice. We designed this study to obtain further information as to efficacy, safety and stability of autologous blood injection for recurrent TMJ dislocation.
キーワード autologous blood injection recurrent temporomandibular joint dislocation
Amo Type Clinical Study Protocols
発行日 2016-08
出版物タイトル Acta Medica Okayama
70巻
4号
出版者 Okayama University Medical School
開始ページ 291
終了ページ 294
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2016 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 27549675
Web of Science KeyUT 000384748600010
フルテキストURL fulltext.pdf
著者 Sakamoto, Yumi| Okui, Tatsuo| Yoneda, Toshiyuki| Ryumon, Shoji| Nakamura, Tomoya| Kawai, Hotaka| Kunisada, Yuki| Ibaragi, Soichiro| Masui, Masanori| Ono, Kisho| Obata, Kyoichi| Shimo, Tsuyoshi| Sasaki, Akira|
キーワード Oral squamous cell cancer HMGB1 Bone destruction Osteoclasts
発行日 2020-10-20
出版物タイトル Biochemical and Biophysical Research Communications
531巻
3号
出版者 Elsevier
開始ページ 422
終了ページ 430
ISSN 0006-291X
NCID AA00564395
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © 2020 The Authors
論文のバージョン publisher
PubMed ID 32800556
DOI 10.1016/j.bbrc.2020.07.120
Web of Science KeyUT 000571663900011
関連URL isVersionOf https://doi.org/10.1016/j.bbrc.2020.07.120
フルテキストURL fulltext.pdf
著者 Obata, Kyoichi| Okui, Tatsuo| Kishimoto, Koji| Ibaragi, Soichiro| Sasaki, Akira|
発行日 2020-04-28
出版物タイトル Case Reports in Medicine
2020巻
出版者 Hindawi
開始ページ 4814519
ISSN 1687-9627
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © 2020 Kyoichi Obata et al.
論文のバージョン publisher
PubMed ID 32411253
DOI 10.1155/2020/4814519
Web of Science KeyUT 000534278000001
関連URL isVersionOf https://doi.org/10.1155/2020/4814519
フルテキストURL IJO54_1_283.pdf
著者 Shimizu, Rieko| Ibaragi, Soichiro| Eguchi, Takanori| Kuwajima, Daisuke| Kodama, Shinichi| Nishioka, Takashi| Okui, Tatsuo| Obata, Kyoichi| Takabatake, Kiyofumi| Kawai, Hotaka| Ono, Kisho| Okamoto, Kuniaki| Nagatsuka, Hitoshi| Sasaki, Akira|
キーワード nicotine head and neck squamous cell carcinoma lymph node metastasis cetuximab
発行日 2018-11-12
出版物タイトル International Journal of Oncology
54巻
1号
出版者 Spandidos Publications
開始ページ 283
終了ページ 294
ISSN 1019-6439
NCID AA10992511
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
論文のバージョン publisher
PubMed ID 30431077
DOI 10.3892/ijo.2018.4631
Web of Science KeyUT 000451845400025
関連URL isVersionOf https://doi.org/10.3892/ijo.2018.4631
著者 Fujioka, Shinsuke| Nishimura, Hiroaki| Nishihara, Katsunobu| Sasaki, Akira| Sunahara, Atsushi| Okuno, Tomoharu| Ueda, Nobuyoshi| Ando, Tsuyoshi| Tao, Yezheng| Shimada, Yoshinori| Hashimoto, Kazuhisa| Yamaura, Michiteru| Shigemori, Keisuke| Nakai, Mitsuo| Nagai, Keiji| Norimatsu, Takayoshi| Nishikawa, Takeshi| Miyanaga, Noriaki| Izawa, Yasukazu| Mima, Kunioki|
発行日 2005-11
出版物タイトル Physical Review Letters
95巻
23号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/49257
フルテキストURL 67_1_55.pdf
著者 Shimo, Tsuyoshi| Nishiyama, Akiyoshi| Jinno, Tokiari| Sasaki, Akira|
抄録 In this article, we report the successful surgical treatment of a patient, 34 years of age, who had a severe gummy smile and a class II malocclusion. The patient had an 11-mm gingival exposure during full smile and a convex profile. A LeFort I osteotomy combined with a horseshoe osteotomy was used for the superior repositioning of the maxilla;then, an intraoral vertical ramus osteotomy (IVRO) and genioplasty were performed for mandibular advancement. The maxilla was acceptably impacted 8mm at the first incisor and 5mm at the first molar. Both the occlusion and facial appearance were significantly improved by this surgical-orthodontic treatment. Our results suggest that the combination of a horseshoe osteotomy with a LeFort I osteotomy is a useful technique for reliable superior repositioning of the maxilla.
キーワード LeFort I osteotomy horseshoe osteotomy gummy smile
Amo Type Case Report
発行日 2013-02
出版物タイトル Acta Medica Okayama
67巻
1号
出版者 Okayama University Medical School
開始ページ 55
終了ページ 60
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 23439509
Web of Science KeyUT 000316829900007
フルテキストURL fulltext.pdf
著者 Murase, Yurika| Kishimoto, Koji| Yoshida, Shoko| Kunisada, Yuki| Kadoya, Koichi| Ibaragi, Soichiro| Sasaki, Akira|
発行日 2020-03-28
出版物タイトル Journal of Surgical Case Reports
3号
出版者 Oxford University Press
開始ページ rjaa061
ISSN 2042-8812
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2020.
論文のバージョン publisher
PubMed ID 32257103
DOI 10.1093/jscr/rjaa061
Web of Science KeyUT 000535663800034
関連URL isVersionOf https://doi.org/10.1093/jscr/rjaa061
フルテキストURL fulltext.pdf
著者 Okui, Tatsuo| Ibaragi, Soichiro| Ono, Kisho| Hasegawa, Kazuaki| Sasaki, Akira|
キーワード peripheral ossifying fibroma
発行日 2020-11-06
出版物タイトル Clinical Case Reports
出版者 Wiley
ISSN 2050-0904
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © 2020 The Authors.
論文のバージョン publisher
DOI 10.1002/ccr3.3494
Web of Science KeyUT 000586702500001
関連URL isVersionOf https://doi.org/10.1002/ccr3.3494
JaLCDOI 10.18926/AMO/55204
フルテキストURL 71_3_219.pdf
著者 Takakura, Hiroaki| Domae, Shohei| Ono, Toshiro| Sasaki, Akira|
抄録  Anticancer drugs induce cell-cycle arrest and apoptosis not only in tumor cells, but also in immune cells. However, many preclinical and clinical findings show that some chemotherapeutic agents can improve the antitumor efficacy of immunotherapy. We immunohistochemically analyzed the degree of immune cell infiltration and the relevance of programmed cell death 1 ligand-1 (PD-L1) expression in surgically resected oral squamous cell carcinoma (OSCC) specimens from patients who had undergone pretreatment with certain chemotherapies and other patients without pretreatment. We divided the patients into the group of neoadjuvant chemotherapy (NAC) patients (n=8) and the nNAC (without NAC) patient group (n=10). We observed that NAC induced infiltrations of CD4, CD8 T cells and CD56 NK cells into the tumor microenvironment. Decreased numbers of Tregs and PD-1-positive cells were observed in the NAC group. No significant difference was observed in the degree of immune-cell infiltration between the patient groups except for CD56 NK cells in the stroma and PD-1 cells in cancer nests. Eighty percent of the nNAC specimens showed intermediate-to-strong PD-L1 protein expression, whereas 75% of the NAC specimens showed down-regulation of the PD-L1 protein, indicating the effectiveness of the chemotherapeutic treatment before surgery.
キーワード oral squamous cell carcinoma programmed cell death 1 ligand-1 tumor microenvironment neoadjuvant chemotherapy immunohistochemistry
Amo Type Original Article
発行日 2017-06
出版物タイトル Acta Medica Okayama
71巻
3号
出版者 Okayama University Medical School
開始ページ 219
終了ページ 226
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28655941
著者 佐々木 朗|
発行日 1990-10-31
出版物タイトル
資料タイプ 学位論文
JaLCDOI 10.18926/21194
タイトル(別表記) Stable isotope study of the hotsprings and volcanoes of Hokkaido, Japan
フルテキストURL pitsr_047_055_067.pdf
著者 松葉谷 治| 酒井 均| 上田 晃| 堤 真| 日下部 実| 佐々木 昭|
抄録 Stable isotope ratios of hydrogen, oxygen, carbon and sulfur of precipitation, thermal and mineral waters, and volcanic gases were measured. The isotopic data combined with chemical and geological information were discussed in terms of origin and evolution of the hotsprings and volcanic gases. The hotsprings along the Uchiura Bay, Oshima Peninsula are mostly near-neutral NaCl-type thermal water and may be divided into three groups : (1) thermal waters isotopically similar to the precipitation of this area, (2) those similar in D/H to the local meteoric waters but enriched by 2 to 3‰ in (18)O compared to the latter, and (3) those enriched significantly in both D and (18)O relative to the local meteoric waters. The first and second types of thermal water probably form from local meteoric water which percolates through "Green Tuff" formations and acquires dissolved chemicals from them. However, high salt concentration and the oxygen isotope shift (thesecond type) may imply that the NaCl-type water of volcanic origin might be involved. On the other hand, the waters of the third group can be explained by mixing of modern sea water into the second type thermal water (in case of Yachigashira) or by incorporation of fossil sea water of Tertiary origin into modern meteoric water (Nigorigawa). Except for Esan, Noboribetsu and Atosanupuri volcanic systems, waters from all the hotsprings and volcanic fumaroles associated with Quaternary volcanic rocks are meteoric in origin. Thermal waters at Esan, Noboribetsu and Atosanupuri have δD = -30~-50 and δ(18)O = -1~+ 3‰ and are enriched in D and (18)O relative to local meteoric water of the respective area. The origin of these waters and the mechanism (s) controlling the isotope ratios could not be made clear by the present study. Interesting is the finding that at Esan, Noboribetsu and Atosanupuri, thermal waters are enriched in D and (18)O relative to near-by fumarolic gases. The enrichment factor is 18 to 26‰ for hydrogen and 4 to 6‰ for oxygen, implying that more than one stages of liquidvapor separation are taking place in underground hydrothermal systems.
出版物タイトル 岡山大学温泉研究所報告
発行日 1978-03-25
47巻
開始ページ 55
終了ページ 67
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 40000321119
著者 山中 玲子| 曽我 賢彦| 縄稚 久美子| 柳 文修| 兒玉 直紀| 中田 貴| 三浦 留美| 羽川 操| 竹内 哲男| 山根 美榮子| 森田 学| 高柴 正悟| 浅海 淳一| 皆木 省吾| 吉山 昌宏| 下野 勉| 窪木 拓男| 佐々木 朗| 森田 潔|
発行日 2009-06
出版物タイトル 岡山歯学会雑誌
28巻
1号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/21159
タイトル(別表記) An isotope study of hot springs in Nagano Prefecture
フルテキストURL pitsr_050_017_024.pdf
著者 松葉谷 治| 酒井 均| 日下部 実| 佐々木 昭|
抄録 Water samples from 28 hotsprings and mineral springs in Nagano Prefecture, central Japan, were examined for their stable isotope ratios of hydrogen, oxygen, carbon, and sulfur. Spring waters of Kashio are highly saline and enriched in heavy isotopes of oxygen and hydrogen (δ(18)O=-2.5~-4.6‰, δD=-54~-57‰). Linear relationships among δD, δ(18)O, and Cl(-) suggest that spring waters are the mixtures of a deep brine and local surface water. Extrapolation of the linear relationships indicates that the deep brine is both isotopically and chemically very similar to the deep brine previously suggested for the springs of Arima, Takarazuka, and Ishibotoke of which δD, δ(18)O, and Cl(-) are estimated as -33‰, +8.0‰, and 44g/l, respectively. A common origin may be warranted among these postulated brines, while their provenance is yet to be worked out. The hot springs in Matsushiro are a Na-Ca-Cl type of high carbonate content. Their hydrogen and oxygen isotope ratios (δD=-71~-46‰, δ(18)O=-9.1~-2.0‰) are higher than the local surface water. On the basis of the relationships among δD, δ(18)O, and Cl(-), they are considered to be the mixtures of fossil sea water and certain water of meteoric origin of which Cl(-) is about 4g/l and δ(18)O is higher by about 3‰ than the local surface water. The latter may be meteoric water circulating in the marine sedimentary formations (Green Tuff formations) with soluble sea salts. Isotopic exchange with carbonate minerals in the formations explains its (18)O enrichment. Spring waters from Yashio and Isobe (Gunma Pref.) as well as Yunosawa and Yatate (Akita Pref.) were previously interpreted to be mixtures of fossil sea water and local surface water of low Cl(-) content. Re-examination of their data revealed that the meteoric waters responsible for these springs contain about 3g/l Cl(-), similar to the value obtained for Matsushiro. However, unlike Matsushiro, the meteoric waters in these areas are found to be isotopically similar to the local surface waters. Waters from other hot springs studied here are of simply meteoric origin, thus belonging to the GreenTuff type water previously defined.
出版物タイトル 岡山大学温泉研究所報告
発行日 1980-03-25
50巻
開始ページ 17
終了ページ 24
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002310953