大西秀樹

著者	Nakanishi, Yutaka\| Shiraha, Hidenori\| Nishina, Shin-ichi\| Tanaka, Shigetomi\| Matsubara, Minoru\| Horiguchi, Shigeru\| Iwamuro, Masaya\| Takaoka, Nobuyuki\| Uemura, Masayuki\| Kuwaki, Kenji\| Hagihara, Hiroaki\| Toshimori, Junichi\| Ohnishi, Hideki\| Takaki, Akinobu\| Nakamura, Shinichiro\| Kobayashi, Yoshiyuki\| Nouso, Kazuhiro\| Yagi, Takahito\| Yamamoto, Kazuhide\|
発行日	2011-01-04
出版物タイトル	BMC Cancer
巻	11巻
資料タイプ	学術雑誌論文

Risk factors for recurrence after transarterial chemoembolization for early-stage hepatocellular carcinoma

著者	Kinugasa, Hideaki\| Nouso, Kazuhiro\| Takeuchi, Yasuto\| Yasunaka, Tetsuya\| Onishi, Hideki\| Nakamura, Shin-ichiro\| Shiraha, Hidenori\| Kuwaki, Kenji\| Hagihara, Hiroaki\| Ikeda, Fusao\| Miyake, Yasuhiro\| Takaki, Akinobu\| Yamamoto, Kazuhide\|
発行日	2012-04
出版物タイトル	Journal of Gastroenterology
巻	47巻
号	4号
資料タイプ	学術雑誌論文

Clinical utility of serum fucosylated hemopexin in Japanese patients with hepatocellular carcinoma

著者	Kobayashi, Sayo\| Nouso, Kazuhiro\| Kinugasa, Hideaki\| Takeuchi, Yasuto\| Tomoda, Takeshi\| Miyahara, Koji\| Hagihara, Hiroaki\| Kuwaki, Kenji\| Onishi, Hideki\| Nakamura, Shinichiro\| Ikeda, Fusao\| Miyake, Yasuhiro\| Shiraha, Hidenori\| Takaki, Akinobu\| Yamamoto, Kazuhide\|
発行日	2012-12
出版物タイトル	Hepatology Research
巻	42巻
号	12号
資料タイプ	学術雑誌論文

Serum oxidative-anti-oxidative stress balance is dysregulated in patients with hepatitis C virus-related hepatocellular carcinoma

著者	Nishimura, Mamoru\| Takaki, Akinobu\| Tamaki, Naofumi\| Maruyama, Takayuki\| Onishi, Hideki\| Kobayashi, Sayo\| Nouso, Kazuhiro\| Yasunaka, Tetsuya\| Koike, Kazuko\| Hagihara, Hiroaki\| Kuwaki, Kenji\| Nakamura, Shinichiro\| Ikeda, Fusao\| Iwasaki, Yoshiaki\| Tomofuji, Takaaki\| Morita, Manabu\| Yamamoto, Kazuhide\|
発行日	2013-01-30
出版物タイトル	Hepatology Research
巻	43巻
号	10号
資料タイプ	学術雑誌論文

The impact of patatin-like phospholipase domain-containing protein 3 polymorphism on hepatocellular carcinoma prognosis

著者	Takeuchi, Yasuto\| Ikeda, Fusao\| Moritou, Yuki\| Hagihara, Hiroaki\| Yasunaka, Tetsuya\| Kuwaki, Kenji\| Miyake, Yasuhiro\| Ohnishi, Hideki\| Nakamura, Shinichiro\| Shiraha, Hidenori\| Takaki, Akinobu\| Iwasaki, Yoshiaki\| Nouso, Kazuhiro\| Yamamoto, Kazuhide\|
発行日	2013-03
出版物タイトル	Journal of Gastroenterology
巻	48巻
号	3号
資料タイプ	学術雑誌論文

Assessment of health-related quality of life and how it predicts the outcome of pegylated interferon and ribavirin therapy for chronic hepatitis C

著者	Matsushita, Hiroshi\| Ikeda, Fusao\| Iwasaki, Yoshiaki\| Seki, Hiroyuki\| Nanba, Shintaro\| Takeuchi, Yasuto\| Moritou, Yuki\| Yasunaka, Tetsuya\| Onishi, Hideki\| Miyake, Yasuhiro\| Takaki, Akinobu\| Nouso, Kazuhiro\| Yamamoto, Kazuhide\|
発行日	2014-02
出版物タイトル	Journal of Gastroenterology and Hepatology
巻	29巻
号	2号
資料タイプ	学術雑誌論文

Aberrant Expression of Keratin 7 in Hepatocytes as a Predictive Marker of Rapid Progression to Hepatic Failure in Asymptomatic Primary Biliary Cirrhosis

JaLCDOI	10.18926/AMO/53520
フルテキストURL	69_3_137.pdf
著者	Seki, Hiroyuki\| Ikeda, Fusao\| Nanba, Shintaro\| Moritou, Yuki\| Takeuchi, Yasuto\| Yasunaka, Tetsuya\| Onishi, Hideki\| Miyake, Yasuhiro\| Takaki, Akinobu\| Nouso, Kazuhiro\| Iwasaki, Yoshiaki\| Nakamura, Minoru\| Yamamoto, Kazuhide\|
抄録	A predictive marker of the rapid progression to hepatic failure is desired for patients with asymptomatic primary biliary cirrhosis (aPBC). We performed a systematic cohort analysis of 101 patients diagnosed as having aPBC and the rapid progression to liver failure in some, by focusing on cholestasis. Cholestasis was assessed by aberrant keratin7 (K-7) expressions in the patientsʼ hepatocytes. Intralobular expressions of K-7 were found in 9 of the 101 patients. The grades of K-7 expression were significantly associated with the levels of alanine aminotransferase, alkaline phosphatase, and total bilirubin at the time of diagnosis, but not with bile duct loss or cholestasis. Stepwise logistic regression analysis revealed that high grades of K-7 expression correlated positively with high levels of total bilirubin. During the follow-up period, 8 patients developed jaundice, and the mean period until the development of jaundice was 5.2 years. The proportional hazards models for the risk of developing jaundice identified a high grade of aberrant K-7 expression in hepatocytes as the only significant risk factor. Aberrant K-7 expression in hepatocytes can be used as an additional marker to predict rapid progression to liver failure in patients with aPBC at the time of diagnosis.
キーワード	primary biliary cirrhosis keratin 7 hepatic failure
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2015-06
巻	69巻
号	3号
出版者	Okayama University Medical School
開始ページ	137
終了ページ	144
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	26101189
Web of Science KeyUT	000356903000002

The Colon Wall Thickness Measured Using Transabdominal Ultrasonography Is Useful for Detecting Mucosal Inflammation in Ulcerative Colitis

フルテキストURL	fulltext.pdf
著者	Takahara, Masahiro\| Hiraoka, Sakiko\| Ohmori, Masayasu\| Takeuchi, Keiko\| Takei, Kensuke\| Yasutomi, Eriko\| Igawa, Shoko\| Yamamoto, Shumpei\| Yamasaki, Yasushi\| Inokuchi, Toshihiro\| Kinugasa, Hideaki\| Harada, Keita\| Ohnishi, Hideki\| Okada, Hiroyuki\|
キーワード	bowel wall thickness Mayo endoscopic subscore classification transabdominal ultrasonography ulcerative colitis
発行日	2022-09-15
出版物タイトル	Internal Medicine
巻	61巻
号	18号
出版者	The Japanese Society of Internal Medicine
開始ページ	2703
終了ページ	2709
ISSN	0918-2918
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Japanese Society of Internal Medicine
論文のバージョン	publisher
PubMed ID	35185047
DOI	10.2169/internalmedicine.8827-21
Web of Science KeyUT	000857218300001
関連URL	isVersionOf https://doi.org/10.2169/internalmedicine.8827-21

大西 秀樹