JaLCDOI 10.18926/AMO/52789
フルテキストURL 68_4_235.pdf
著者 Ono, Tetsuichiro| Shikata, Kenichi| Obika, Mikako| Miyatake, Nobuyuki| Kodera, Ryo| Hirota, Daisyo| Wada, Jun| Kataoka, Hitomi| Ogawa, Daisuke| Makino, Hirofumi|
抄録 The aim of this study was to clarify the factors associated with the remission and/or regression of microalbuminuria in Japanese patients with type 2 diabetes mellitus. We retrospectively analyzed the data of 130 patients with type 2 diabetes mellitus with microalbuminuria for 2-6 years (3.39±1.31 years). Remission was defined as improving from microalbuminuria to normoalbuminuria using the albumin/creatinine ratio (ACR), and regression of microalbuminuria was defined as a decrease in ACR of 50% or more from baseline. Progression of microalbuminuria was defined as progressing from microalbuminuria to overt proteinuria during the follow-up period. Among 130 patients with type 2 diabetes mellitus with microalbuminuria, 57 and 13 patients were defined as having remission and regression, respectively, while 26 patients progressed to overt proteinuria. Sex (female), higher HDL cholesterol and lower HbA1c were determinant factors associated with remission/regression of microalbuminuria by logistic regression analysis. Lower systolic blood pressure (SBP) was also correlated with remission/regression, but not at a significant level. These results suggest that proper control of blood glucose, BP and lipid profiles may be associated with remission and/or regression of type 2 diabetes mellitus with microalbuminuria in clinical practice.
キーワード microalbuminuria type 2 diabetes mellitus remission regression
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2014-08
68巻
4号
出版者 Okayama University Medical School
開始ページ 235
終了ページ 241
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25145409
Web of Science KeyUT 000340687500005
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/52828
フルテキストURL BMCMedEduc_19_1_87.pdf
著者 Yamamoto, Akira| Obika, Mikako| Mandai, Yasuhiro| Murakami, Taku| Miyoshi, Tomoko| Ino, Hideo| Kataoka, Hitomi| Otsuka, Fumio|
キーワード Simulation-based learning Peer-assisted learning Lecture Postgraduate education Junior residents
発行日 2019-03-20
出版物タイトル BMC Medical Education
19巻
1号
出版者 BMC
開始ページ 87
ISSN 1472-6920
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン publisher
PubMed ID 30894162
DOI 10.1186/s12909-019-1509-y
Web of Science KeyUT 000462328100001
関連URL isVersionOf https://doi.org/10.1186/s12909-019-1509-y
JaLCDOI 10.18926/AMO/57370
フルテキストURL 73_5_403.pdf
著者 Ando, Akemi| Mitsuhashi, Toshiharu| Honda, Mitsugi| Hanayama, Yoshihisa| Hasegawa, Kou| Obika, Mikako| Kataoka, Hitomi| Otsuka, Fumio|
抄録 Osteoporosis increases the risk of bone fractures. It is diagnosed based on an individual’s bone mineral density (BMD) or a fracture without trauma. BMD is usually measured by the dual energy X-ray absorptiometry (DXA) method. Here we investigated factors for the earliest possible prediction of decreased BMD by examining the relationships between patients’ BMD values and changes in the patients’ physical and laboratory values. We retrospectively reviewed the medical records of 149 patients who visited our department in 2014-2015 for a variety of reasons and underwent an area BMD examination by DXA. We analyzed the relationships between decreasing BMD and the patients’ gender, age, body mass index (BMI), medical background, hemoglobin, electrolytes, and thyroid function. Thirty-nine of the patients were diagnosed with osteoporosis based on their T-scores. An adjusted analysis showed that female gender, aging, and increased serum calcium level were significantly related to decreasing femoral BMD, whereas high BMI was associated with an increase in femoral BMD. Collectively the results indicate that for the early detection of low BMD, it is important for general-practice physicians to consider conducting a BMD checkup when treating female and elderly patients with a low BMI and/or elevated serum calcium level.
キーワード bone mineral density (BMD) body mass index (BMI) female gender hypercalcemia osteoporosis
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2019-10
73巻
5号
出版者 Okayama University Medical School
開始ページ 403
終了ページ 411
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 31649366
Web of Science KeyUT 000491886600005
JaLCDOI 10.18926/AMO/57711
フルテキストURL 73_6_479.pdf
著者 Suganami, Yu| Oka, Kosuke| Hanayama, Yoshihisa| Honda, Hiroyuki| Hamahara, Jun| Obika, Mikako| Kariyama, Kazuya| Kishida, Masayuki| Otsuka, Fumio|
抄録 To clarify the potential relevance of patients’ chief complaints at a general medicine department to their self-rating depression scale (SDS) and frequency scale for symptoms of gastroesophageal reflux disease (GERD) (FSSG) scores, we analyzed data of 478 patients who visited our general medicine department. The chief complaints (553 symptoms of 447 patients) were categorized into major symptom-based groups: respiratory (31%), circulatory (3%), gastrointestinal (GI) tract (26%), neurology (8%), orthopedic and skin (10%), and systemic (22%) symptoms. The SDS score tended to be higher in females and younger patients. The FSSG score did not differ by gender but was higher in younger patients. The patients receiving social welfare had higher SDS and FSSG scores. A close inter-relationship between the FSSG (including both degrees of reflux and dysmotility) and SDS was observed in all patients. Although the averages of the SDS and FSSG scores were not significantly different among the symptom-based categories, we observed significantly positive correlations between the FSSG and SDS in each category, suggesting that depressive status may be closely related to GERD-related symptoms regardless of the patients’ chief complaints. An initial checkup of patients’ psychological condition and/or GERD-like symptoms could help screen for latent disorders in outpatients with uncertain complaints.
キーワード chief complaints frequency scale for the symptoms of gastroesophageal reflux disease (FSSG) self-rating depression scale (SDS) welfare
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2019-12
73巻
6号
出版者 Okayama University Medical School
開始ページ 479
終了ページ 486
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 31871329
Web of Science KeyUT 000503431400002
JaLCDOI 10.18926/AMO/57950
フルテキストURL 74_1_33.pdf
著者 Honda, Hiroyuki| Hanayama, Yoshihisa| Obika, Mikako| Hasegawa, Kou| Hamahara, Jun| Kishida, Masayuki| Hagiya, Hideharu| Ogawa, Hiroko| Kataoka, Hitomi| Otsuka, Fumio|
抄録 A relationship between diabetes and depression is apparent. To clarify the clinical relevance of diabetic patients’ gastroesophageal symptoms to their psychological status, we retrospectively analyzed the data from a Selfrating Depression Scale (SDS) and a Frequency Scale for Symptoms of Gastroesophageal reflux disease (FSSG) among 143 type 2 diabetic patients who visited a general medicine department. Among the 45 Japanese patients enrolled, the group with relatively high SDS scores (≥ 36) showed higher (FSSG) dysmotility symptom scores versus the low-SDS (< 36) group, although the 2 groups’ characteristics and laboratory data were not significantly different. Positive correlations of postprandial plasma glucose (PPG) levels with FSSG scores (R=0.321, p<0.05), particularly with reflux scores (R=0.455, p<0.01) were revealed. PPG and HbA1c levels were not correlated with SDS scores. The patients’ SDS scores were significantly correlated with their FSSG scores (R=0.41, p<0.01), suggesting that depressive status is linked to GERD-related manifestations. Considering that the patients’ PPG levels were correlated with GERD-related symptoms, diabetic patients’ blood glucose levels are associated with depressive status. Collectively, key symptoms related to GERD and glucose level values would be helpful
キーワード blood glucose type 2 diabetes mellitus gastroesophageal reflux depressive status postprandial plasma glucose
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2020-02
74巻
1号
出版者 Okayama University Medical School
開始ページ 33
終了ページ 40
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32099246
Web of Science KeyUT 000516606200005
NAID 120006795617
フルテキストURL fulltext.pdf
著者 Yamamoto, Akira| Nishimura, Yoshito| Obika, Mikako| Morizane, Yuki| Otsuka, Fumio|
キーワード anemia anemic retinopathy rectal cancer retinal detachment
発行日 2020-04-13
出版物タイトル Clinical Case Reports
8巻
7号
出版者 Wiley
開始ページ 1304
終了ページ 1305
ISSN 2050-0904
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 The Authors.
論文のバージョン publisher
NAID 120006862787
DOI 10.1002/ccr3.2833
Web of Science KeyUT 000525973300001
関連URL isVersionOf https://doi.org/10.1002/ccr3.2833
フルテキストURL fulltext.pdf
著者 Nishimura, Yoshito| Hagiya, Hideharu| Kawano, Kaoru| Yokota, Yuya| Oka, Kosuke| Iio, Koji| Hasegawa, Kou| Obika, Mikako| Haruma, Tomoko| Ono, Sawako| Masuyama, Hisashi| Otsuka, Fumio|
キーワード Non-typable Haemophilus influenzae Bacteremia beta-Lactamase-nonproducing ampicillin-resistance Adenomyosis Case report
発行日 2020-07-16
出版物タイトル BMC Infectious Diseases
20巻
1号
出版者 BMC
開始ページ 521
ISSN 1471-2334
NCID AA1203502X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s). 2020
論文のバージョン publisher
PubMed ID 32678023
DOI 10.1186/s12879-020-05193-2
Web of Science KeyUT 000552431500010
関連URL isVersionOf https://doi.org/10.1186/s12879-020-05193-2
JaLCDOI 10.18926/AMO/60797
フルテキストURL 74_5_381.pdf
著者 Yamamoto, Koichiro| Hanayama, Yoshihisa| Hasegawa, Kou| Tokumasu, Kazuki| Miyoshi, Tomoko| Hagiya, Hideharu| Ogawa, Hiroko| Obika, Mikako| Itoshima, Koichi| Otsuka, Fumio|
抄録 To clarify the relevance of prolactin (PRL) to clinical parameters in patients who visited our general medicine department, medical records of 353 patients in whom serum PRL levels were measured during the period from 2016 to 2018 were retrospectively reviewed. Data for 140 patients (M/F: 42/98) were analyzed after excluding patients lacking detailed records and patients taking dopaminergic agents. Median serum PRL levels were significantly lower in males than females: 6.5 ng/ml (IQR: 4.2-10.3) versus 8.1 ng/ml (5.9-12.9), respectively. Pain and general fatigue were the major symptoms at the first visit, and past histories of hypertension and dyslipidemia were frequent. Male patients with relatively high PRL levels (≥ 10 ng/ml) had significantly lower levels of serum albumin and significantly higher levels of serum LDH than those with low PRL (< 10 ng/ml). There were significant correlations of male PRL level with the erythrocyte sedimentation rate (R=0.62), serum LDH level (R=0.39) and serum albumin level (R=−0.52), while the level of serum CRP (R=0.33) showed an insignificant but weak positive correlation with PRL level. Collectively, these results show that PRL levels had gender-specific relevance to various clinical factors, with PRL levels in males being significantly related to inflammatory status.
キーワード hormones hyperprolactinemia inflammation pituitary prolactin
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2020-10
74巻
5号
出版者 Okayama University Medical School
開始ページ 381
終了ページ 389
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33106693
Web of Science KeyUT 000581970100002
NAID 120006892923
フルテキストURL fulltext.pdf
著者 Yamamoto, Akira| Fujii, Nobuharu| Obika, Mikako| Yamashita, Taro| Otsuka, Fumio|
キーワード localized AL amyloidosis ymphadenopathy PET-CT systemic AL amyloidosis
発行日 2020-10-01
出版物タイトル Internal Medicine
59巻
19号
出版者 The Japanese Society of Internal Medicine
開始ページ 2415
終了ページ 2418
ISSN 1349-7235
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 by The Japanese Society of Internal Medicine
論文のバージョン publisher
PubMed ID 32611959
DOI 10.2169/internalmedicine.4651-20
関連URL isVersionOf https://doi.org/10.2169/internalmedicine.4651-20
フルテキストURL fulltext.pdf
著者 Nishimura, Yoshito| Hagiya, Hideharu| Obika, Mikako| Otsuka, Fumio|
キーワード septic pulmonary embolism blood culture procalcitonin
発行日 2020-11-27
出版物タイトル Pathogens
9巻
12号
出版者 MDPI
開始ページ 995
ISSN 2076-0817
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 by the authors.
論文のバージョン publisher
PubMed ID 33260940
DOI 10.3390/pathogens9120995
Web of Science KeyUT 000602562400001
関連URL isVersionOf https://doi.org/10.3390/pathogens9120995
JaLCDOI 10.18926/AMO/61424
フルテキストURL 75_1_1.pdf
著者 Hamahara, Jun| Honda, Hiroyuki| Yamamoto, Koichiro| Tokumasu, Kazuki| Hanayama, Yoshihisa| Hagiya, Hideharu| Obika, Mikako| Ueda, Keigo| Kishida, Masayuki| Otsuka, Fumio|
抄録 To determine the clinical characteristics of low androgen status in adult males with diabetes, we retrospectively analyzed the medical records of patients with type 2 diabetes mellitus in whom serum free testosterone (FT) levels were examined for 1 year. Among the 46 patients (56 ± 1.5 years old), decreases in serum FT levels to < 8.5 pg/ml (indicating the occurrence of late-onset hypogonadism [LOH]) were detected in 18 (39%). The per-centages of patients with low FT levels were high in the ≥ 50 years age group (83%), the HbA1c < 7% group (67%), and the 25 ≤ BMI < 30 kg/m2 group (56%). The serum FT levels tended to decrease age-dependently. The level of HbA1c was significantly correlated with the Heinemann Aging Male Symptoms (AMS) score (R = 0.47). The low-FT group had decreased levels of hemoglobin. Of note, the serum FSH level (R = −0.32) was negatively correlated with the serum FT level, whereas the serum TSH level (R = 0.36) was positively correlated with the serum FT level. Collectively, these results revealed that many diabetic males may have low FT levels and that the AMS score is related to the HbA1c level. A slightly anemic condition, thyroid dysfunction, and obesity (class 1) might be involved in LOH in middle-aged diabetic males.
キーワード androgen diabetes mellitus late-onset hypogonadism testosterone thyroid function
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 1
終了ページ 8
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649607
フルテキストURL fulltext.pdf
著者 Nishimura, Yoshito| Ochi, Kanako| Tokumasu, Kazuki| Obika, Mikako| Hagiya, Hideharu| Kataoka, Hitomi| Otsuka, Fumio|
キーワード COVID-19 online education depression pandemic anxiety medical student
発行日 2021-02-18
出版物タイトル Journal of Medical Internet Research
23巻
2号
出版者 JMIR Publications
開始ページ e25232
ISSN 1438-8871
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © Yoshito Nishimura, Kanako Ochi, Kazuki Tokumasu, Mikako Obika, Hideharu Hagiya, Hitomi Kataoka, Fumio Otsuka.
論文のバージョン publisher
PubMed ID 33556033
DOI 10.2196/25232
Web of Science KeyUT 000619233300006
関連URL isVersionOf https://doi.org/10.2196/25232
フルテキストURL fulltext.pdf
著者 Li, Koki| Otsuka, Yuki| Nakano, Yasuhiro| Omura, Daisuke| Hasegawa, Kou| Obika, Mikako| Ueda, Keigo| Kataoka, Hitomi| Otsuka, Fumio|
キーワード chronic fatigue syndrome endothelial dysfunction microvascular angina myalgic encephalomyelitis vasospastic angina
発行日 2021-03-06
出版物タイトル Diagnostics
11巻
3号
出版者 MDPI
開始ページ 460
ISSN 2075-4418
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 by the authors.
論文のバージョン publisher
PubMed ID 33800953
DOI 10.3390/diagnostics11030460
Web of Science KeyUT 000633585100001
関連URL isVersionOf https://doi.org/10.3390/diagnostics11030460
フルテキストURL fulltext.pdf
著者 Fujita-Yamashita, Manami| Yamamoto, Koichiro| Honda, Hiroyuki| Hanayama, Yoshihisa| Tokumasu, Kazuki| Nakano, Yasuhiro| Hasegawa, Kou| Hagiya, Hideharu| Obika, Mikako| Ogawa, Hiroko| Otsuka, Fumio|
キーワード aging bone metabolism calcium cyp27b1 vitamin d
発行日 2021-09-18
出版物タイトル Cureus
13巻
9号
出版者 Cureus Inc
開始ページ e18070
ISSN 2168-8184
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 Fujita-Yamashita et al.
論文のバージョン publisher
DOI 10.7759/cureus.18070
Web of Science KeyUT 000701650300002
関連URL isVersionOf https://doi.org/10.7759/cureus.18070
フルテキストURL fulltext.pdf
著者 Otsuka, Yuki| Tokumasu, Kazuki| Nakano, Yasuhiro| Honda, Hiroyuki| Sakurada, Yasue| Sunada, Naruhiko| Omura, Daisuke| Hasegawa, Kou| Hagiya, Hideharu| Obika, Mikako| Ueda, Keigo| Kataoka, Hitomi| Otsuka, Fumio|
キーワード long covid covid-19 aftercare clinic general fatigue general physician post-acute sequelae of covid-19
発行日 2021-10-07
出版物タイトル Cureus
13巻
10号
出版者 Cureus Inc.
開始ページ e18568
ISSN 2168-8184
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 Otsuka et al.
論文のバージョン publisher
DOI 10.7759/cureus.18568
Web of Science KeyUT 000709721800008
関連URL isVersionOf https://doi.org/10.7759/cureus.18568
フルテキストURL fulltext.pdf
著者 Ishida, Tomoharu| Hagiya, Hideharu| Honda, Hiroyuki| Nakano, Yasuhiro| Ogawa, Hiroko| Obika, Mikako| Ueda, Keigo| Kataoka, Hitomi| Hanayama, Yoshihisa| Otsuka, Fumio|
発行日 2021-11-12
出版物タイトル Plos One
16巻
11号
出版者 Public Library Science
開始ページ e0259633
ISSN 1932-6203
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 Ishida et al.
論文のバージョン publisher
PubMed ID 34767587
DOI 10.1371/journal.pone.0259633
Web of Science KeyUT 000755249300037
関連URL isVersionOf https://doi.org/10.1371/journal.pone.0259633
フルテキストURL fulltext.pdf
著者 Yamamoto, Koichiro| Nakano, Yasuhiro| Tokumasu, Kazuki| Honda, Hiroyuki| Hasegawa, Kou| Sato, Asuka| Ogawa, Hiroko| Obika, Mikako| Hanayama, Yoshihisa| Otsuka, Fumio|
キーワード cinacalcct evocalcet hypercalccmia primary hyperparathyroidism
発行日 2022-04-08
出版物タイトル Clinical Case Reports
10巻
4号
出版者 Wiley
開始ページ e05713
ISSN 2050-0904
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2022 The Authors.
論文のバージョン publisher
PubMed ID 35425612
DOI 10.1002/ccr3.5713
Web of Science KeyUT 000781095000001
関連URL isVersionOf https://doi.org/10.1002/ccr3.5713
フルテキストURL fulltext.pdf
著者 Hagiya, Hideharu| Otsuka, Yuki| Tokumasu, Kazuki| Honda, Hiroyuki| Nishimura, Yoshito| Obika, Mikako| Otsuka, Fumio|
発行日 2022-04-21
出版物タイトル PLOS ONE
17巻
4号
出版者 Public Library Science
開始ページ e0267587
ISSN 1932-6203
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2022 Hagiya et al.
論文のバージョン publisher
PubMed ID 35446911
DOI 10.1371/journal.pone.0267587
Web of Science KeyUT 000795468200022
関連URL isVersionOf https://doi.org/10.1371/journal.pone.0267587
フルテキストURL fulltext.pdf
著者 Tokumasu, Kazuki| Ueda, Keigo| Honda, Hiroyuki| Sunada, Naruhiko| Sakurada, Yasue| Matsuda, Yui| Nakano, Yasuhiro| Hasegawa, Toru| Otsuka, Yuki| Obika, Mikako| Hagiya, Hideharu| Kataoka, Hitomi| Otsuka, Fumio|
キーワード general fatigue herbal medicine Kampo medicine long COVID
発行日 2022-05-28
出版物タイトル Medicina
58巻
6号
出版者 MDPI
開始ページ 730
ISSN 1010-660X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2022 by the authors.
論文のバージョン publisher
PubMed ID 35743993
DOI 10.3390/medicina58060730
Web of Science KeyUT 000818259300001
関連URL isVersionOf https://doi.org/10.3390/medicina58060730
フルテキストURL fulltext.pdf
著者 Tokumasu, Kazuki| Nishimura, Yoshito| Sakamoto, Yoko| Obika, Mikako| Kataoka, Hitomi| Otsuka, Fumio|
キーワード COVID-19 medical student medical education in-person communication online communication stress perception
発行日 2023-01-15
出版物タイトル International Journal of Environmental Research and Public Health
20巻
2号
出版者 MDPI
開始ページ 1579
ISSN 1660-4601
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 by the authors.
論文のバージョン publisher
PubMed ID 36674333
DOI 10.3390/ijerph20021579
Web of Science KeyUT 000915112800001
関連URL isVersionOf https://doi.org/10.3390/ijerph20021579