フルテキストURL fulltext.pdf
著者 Maeda, Yukihide| Kariya, Shin| Uraguchi, Kensuke| Takahara, Junko| Fujimoto, Shohei| Sugaya, Akiko| Nishizaki, Kazunori|
キーワード DNA microarray Immunohistochemistry Mouse cochlea Neurotransmission Noise-induced hearing loss RNA-seq Real-time RT-PCR Transcription factor
発行日 2020-05-15
出版物タイトル Neuroscience Research
出版者 Elsevier
ISSN 01680102
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 The Authors.
論文のバージョン publisher
PubMed ID 32417196
DOI 10.1016/j.neures.2020.05.001
関連URL isVersionOf https://doi.org/10.1016/j.neures.2020.05.001
タイトル(別表記) Peritonsillar abscess with otorrhea
フルテキストURL fulltext.pdf
著者 大道 亮太郎| 片岡 祐子| 石原 久司| 西﨑 和則|
発行日 2013-05
出版物タイトル 日本耳鼻咽喉科感染症研究会会誌
31巻
1号
出版者 日本耳鼻咽喉科感染症研究会
開始ページ 175
終了ページ 178
ISSN 09133976
NCID AN10042649
資料タイプ 学術雑誌論文
言語 日本語
OAI-PMH Set 岡山大学
著作権者 ©日本耳鼻咽喉科感染症研究会
論文のバージョン publisher
オフィシャル URL http://www.jsiao.umin.jp/infect-archive/number/42.html|
フルテキストURL fulltext.pdf
著者 Uraguchi, Kensuke| Kozakura, Kenichi| Oka, Satoshi| Higaki, Takaya| Makihara, Seiichiro| Imai, Toshi| Doi, Akira| Ohta, Tsuyoshi| Kariya, Shin| Nishizaki, Kazunori|
キーワード Rhinocerebral mucormycosis Acute rhinosinusitis Brain abscess Endoscopic endonasal skull base surgery Acute monocytic leukemia
発行日 2020-12
出版物タイトル Medical Mycology Case Reports
30巻
出版者 Elsevier
開始ページ 22
終了ページ 25
ISSN 2211-7539
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 The Authors.
論文のバージョン publisher
PubMed ID 33083212
DOI 10.1016/j.mmcr.2020.09.004
Web of Science KeyUT 000600608700007
関連URL isVersionOf https://doi.org/10.1016/j.mmcr.2020.09.004
フルテキストURL fulltext.pdf
著者 Uraguchi, Kensuke| Maeda, Yukihide| Takahara, Junko| Omichi, Ryotaro| Fujimoto, Shohei| Kariya, Shin| Nishizaki, Kazunori| Ando, Mizuo|
発行日 2021-10-22
出版物タイトル PLOS ONE
16巻
10号
出版者 Public Library Science
開始ページ e0258977
ISSN 1932-6203
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 Uraguchi et al.
論文のバージョン publisher
PubMed ID 34679122
DOI 10.1371/journal.pone.0258977
Web of Science KeyUT 000733392900043
関連URL isVersionOf https://doi.org/10.1371/journal.pone.0258977
著者 Noda, Yohei| Nishizaki, Kazunori| Yoshinobu, Junko| Orita, Yorihisa| Tsujigiwa, Hidetsugu| Yamada, Masao|
発行日 2013-09
出版物タイトル Acta Oto-laryngologica
133巻
9号
資料タイプ 学術雑誌論文
著者 Hirai, Misato| Maeda, Yukihide| Fukushima, Kunihiro| Sugaya, Akiko| Kataoka, Yuko| Nishizaki, Kazunori|
発行日 2011-09-14
出版物タイトル NeuroReport
22巻
13号
資料タイプ 学術雑誌論文
著者 Sugaya, Akiko| Fukushima, Kunihiro| Kasai, Norio| Ojima, Toshiyuki| Takahashi, Goro| Nakagawa, Takashi| Murai, Seiko| Nakajima, Yasoichi| Nishizaki, Kazunori|
発行日 2014-07
出版物タイトル Annals of Otology, Rhinology & Laryngology
123巻
7号
資料タイプ 学術雑誌論文
著者 片岡 祐子| 西﨑 和則|
発行日 2014-12-01
出版物タイトル 岡山医学会雑誌
126巻
3号
資料タイプ 学術雑誌論文
著者 野宮 理恵| 岡野 光博| 藤原 田鶴子| 西﨑 和則|
発行日 2009-08-03
出版物タイトル 岡山医学会雑誌
121巻
2号
資料タイプ 学術雑誌論文
著者 高原 滋夫| 小倉 義郎| 増田 游| 西岡 慶子| 西崎 和則| 杉浦 友昭| 古川 勝朗| 水河 幸夫| 黒田 泰生| 緒方 正名| 大倉 興司|
発行日 1986-06-30
出版物タイトル 岡山医学会雑誌
98巻
5-6号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/30373
フルテキストURL fulltext.pdf
著者 Okada, Satoko| Ohtsuka, Aiji| Akagi, Hirofumi| Nishizaki, Kazunori| Masuda, Yu|
抄録

It has previously been confirmed that the guinea pig has aggregations of 10-20 lymphoid follicles at the junction of the nasal cavity and the nasopharyngeal duct. The vascular architecture of this nasal-associated lymphoid tissue (NALT) was studied by the corrosion cast/scanning electron microscope method. The NALT was supplied by branches of the inferior nasal artery. These afferent arterial branches gave off arterioles to the follicles and the interfollicular regions, where the arterioles ramified into capillaries. Some of these arterioles reached the subepithelial region to form a single-layer dense capillary network. The subepithelial capillaries gathered into short collecting venules, which in turn drained into high endothelial venules (HEV) in the interfollicular region. The HEV, which also receives tributaries from the follicular and interfollicular capillary plexuses, descended in the interfollicular regions and finally flowed into the efferent veins at the bottom of the NALT. Indentations impressed by high endothelial cells (HEC) were prominent on the surface of the HEV casts, and their frequency was larger in the upper course or segments than in the lower. This suggests that the incidence of HEC in the upper segments is higher than in the lower segments, and these findings are consistent with the hypothesis that some substances which are taken up into the subepithelial capillaries and transported to the venules induce differentiation and maintain of HEVs.

キーワード nasal-associated lymphoid tisse vascular corrosion cast microvascular architecture high endothelial venule guinea pig
Amo Type Article
出版物タイトル Acta Medica Okayama
発行日 1995-08
49巻
4号
出版者 Okayama University Medical School
開始ページ 213
終了ページ 219
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
論文のバージョン publisher
査読 有り
PubMed ID 7502682
Web of Science KeyUT A1995RR97800006
JaLCDOI 10.18926/AMO/30655
フルテキストURL fulltext.pdf
著者 Nishioka, Keiko| Masuda, Yu| Nishizaki, Kazunori| Ogura, Yoshio|
抄録

Unilateral cystic inner ear anomalies were diagnosed in two siblings, a 9 year old boy and a 6 year old girl. X-ray examination of the temporal bone was performed, together with audiological examinations and vestibular function tests. The common tomographic X-ray findings consisted of an enlarged solitary sac type deformity of the vestibule with narrowing of the internal auditory canal, severe hypoplasia of the anterior semicircular canal and no visualized cochlea. Pure-tone audiometry revealed severe mixed type of hearing loss in the right ear in both children. The test for vestibular function showed no response to caloric testing.

キーワード inner ear anomaliy siblings
Amo Type Brief Note
出版物タイトル Acta Medica Okayama
発行日 1982-08
36巻
4号
出版者 Okayama University Medical School
開始ページ 321
終了ページ 324
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
論文のバージョン publisher
査読 有り
PubMed ID 7136861
Web of Science KeyUT A1982PE61100011
JaLCDOI 10.18926/AMO/30796
フルテキストURL fulltext.pdf
著者 Miyahara, Satoko| Nakada, Michihiro| Nishizaki, Kazunori| Kawarai, Yasuyuki| Nishioka, Keiko| Hino, Hiroo|
抄録

We studied 92 patients with allergic rhinitis in Syodoshima, Japan, during the pollen season between April and June to evaluate the cross-reactivity to different antigens, including pollen from the olive tree (Olea europaea) and orchard grass (Dactylis glomerata). Olive tree pollen was present in the atmosphere for 23 days, from May 19 to June 12, 1994. Specific IgE antibodies for olive tree pollen antigen were present in 21 (26.9%) of the 78 patients with allergic rhinitis. Nine (24.3%) of the 37 patients with allergic rhinitis exhibited positive skin reactivity to an extract of olive tree pollen. Fifteen (88.2 %) of the 17 patients who had IgE reactivity in their sera to olive tree pollen antigen demonstrated allergic reactions to an extract of olive tree pollen. Specific IgE antibodies for orchard grass pollen antigen were present in 43 (48.3%) of the 89 patients with allergic rhinitis and 20 (95.2%) of the 21 patients who had IgE reactivity in their sera to olive tree pollen antigen. The inhibition test using the CAP System revealed that the reactivity of the IgE antibody specific for olive tree pollen antigen was inhibited dose-dependently by an extract of orchard grass pollen. These findings show that there is a reaction in some patients with grass (Gramineae) pollinosis that might be induced by olive tree pollen.

キーワード olive tree pollen pollinosis cross-reactivity grass pollen orchard grass
Amo Type Article
出版物タイトル Acta Medica Okayama
発行日 1997-06
51巻
3号
出版者 Okayama University Medical School
開始ページ 167
終了ページ 171
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
論文のバージョン publisher
査読 有り
PubMed ID 9227797
Web of Science KeyUT A1997XJ12700009
JaLCDOI 10.18926/AMO/30802
フルテキストURL fulltext.pdf
著者 Kimura, Nobuhiko| Nishioka, Keiko| Nishizaki, Kazunori| Ogawa, Teruhiro| Naitou, Yoshihiro| Masuda, Yu|
抄録

 We studied the clinical efficacy of roxithromycin (RXM) administered at the daily dosage of one tablet (150mg) for 3 months in 30 patients with chronic sinusitis. The effectiveness of this drug was evaluated on a four-point scale. Subjective and objective symptoms disappeared or decreased markedly, especially postnasal drip and nature of discharge in 80 percent or more of the patients. All symptoms significantly decreased (P < 0.001; headache P < 0.05), except for the sensation of foul odor. Symptoms improved even in those cases in which Haemophilus influenzae was detected. It is suggested that RXM produces some clinically beneficial effect through an immunological and or anti-inflammatory mechanisms in addition to its antibiotic effect.

キーワード roxithromycin clinical evaluation chronic sinusitis long-term low-dose administration
Amo Type Article
出版物タイトル Acta Medica Okayama
発行日 1997-02
51巻
1号
出版者 Okayama University Medical School
開始ページ 33
終了ページ 37
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
論文のバージョン publisher
査読 有り
PubMed ID 9057933
Web of Science KeyUT A1997WL24600006
JaLCDOI 10.18926/AMO/32301
フルテキストURL fulltext.pdf
著者 Endo, Ryutaro| Murakami, Shinichiro| Masuda, Yu| Taguchi, Takehito| Ohtsuka, Aiji| Nishizaki, Kazunori| Murakami, Takuro|
抄録

The present study showed that many neurons in the adult rat brain possessed a perineuronal sulfated proteoglycan surface coat which reacted to cationic iron colloid and aldehyde fuchsin. This surface coat was stained supravitally with Ehrlich's methylene blue and doubly stained with Ehrlich's methylene blue and aldehyde fuchsin. The surface coat was also stained with Gomori's ammoniacal silver and doubly stained with Gomori's ammoniacal silver and cationic iron colloid. The surface coat was usually expressed together with a nerve cell surface glycoprotein net detectable with lectin Wisteria floribunda agglutinin. These findings indicate that the perineuronal proteoglycan surface coat is identical to Cajal's superficial reticulum and contains some collagenous elements. It was further demonstrated that collagenase digestion erased Gomori's ammoniacal silver impregnation within the perineuronal proteoglycan surface coat.

キーワード brain extracellular matrix perineuronal proteoglycans cell surface glycoproteins
Amo Type Article
出版物タイトル Acta Medica Okayama
発行日 2000-06
54巻
3号
出版者 Okayama University Medical School
開始ページ 111
終了ページ 118
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
論文のバージョン publisher
査読 有り
PubMed ID 10925735
Web of Science KeyUT 000087965700003
タイトル(別表記) Dreaming of regenerative medicine for olfactory dysfunction
フルテキストURL 132_126.pdf
著者 西﨑 和則|
抄録 Olfactory dysfunction consists of conductive olfactory dysfunction, sensorineural olfactory dysfunction, and central olfactory dysfunction. Conductive olfactory dysfunction can be improved by nasal steroids and/or endoscopic sinus surgery. On the other hand, there is no effective treatment for sensorineural olfactory dysfunction. Therefore, the use of regenerative medicine for sensorineural olfactory dysfunction was investigated. To improve sensorineural olfactory dysfunction, it is essential that olfactory cell regeneration and re-synaptogenesis with originally-innervated upper neurons in the olfactory bulb glomerulus. These problems were examined using bone marrow transplantation and a traumatic head injury model. Although the potential of regenerative medicine for olfactory cells using bone marrow cells has been shown, reconstructing correct synapse formation in the olfactory bulb is a difficult problem to be solved.
キーワード 嗅覚障害 再生医療 再シナプス形成
出版物タイトル 岡山医学会雑誌
発行日 2020-12-01
132巻
3号
開始ページ 126
終了ページ 130
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.132.126
言語 日本語
著作権者 Copyright (c) 2020 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.132.126
NAID 130007950574
JaLCDOI 10.18926/AMO/66150
フルテキストURL 77_6_589.pdf
著者 Omichi, Ryotaro| Kariya, Shin| Maeda, Yukihide| Fukushima, Kunihiro| Kataoka, Yuko| Sugaya, Akiko| Nishizaki, Kazunori| Ando, Mizuo|
抄録 Choosing the optimal side for cochlear implantation (CI) remains a major challenge because of the lack of evidence. We investigated the choice of the surgery side for CI (i.e., the better- or poorer-hearing ear) in patients with asymmetric hearing. Audiological records of 74 adults with a unilateral hearing aid who had undergone surgery at Okayama University Hospital were reviewed. The definition of ‘better-hearing ear’ was the aided ear, and the unaided ear was considered the poorer-hearing ear. We performed a multiple regression analysis to identify potential predictors of speech recognition performance after unilateral CI in the patients. Fifty-two patients underwent CI in the poorer-hearing ear. The post-Ci bimodal hearing rate was far higher in the poorer-ear group (77.8% vs. 22.2%). A multivariate analysis revealed that prelingual hearing loss and the patient’s age at CI significantly affected the speech recognition outcome (beta coefficients: 24.6 and −0.33, 95% confidence intervals [11.75-37.45] and [−0.58 to −0.09], respectively), but the CI surgery side did not (−6.76, [−14.92-1.39]). Unilateral CI in the poorer-hearing ear may therefore be a reasonable choice for adult patients with postlingual severe hearing loss, providing a greater opportunity for postoperative bimodal hearing.
キーワード cochlear implantation poorer hearing ear better hearing ear hearing aids speech recognition
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-12
77巻
6号
出版者 Okayama University Medical School
開始ページ 589
終了ページ 593
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り