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ID 13442
Eprint ID
13442
フルテキストURL
Thumnail 116_215.pdf 7.49 MB
著者
増山 寿 岡山大学医学部・歯学部附属病院 産科婦人科
キーワード
pregnane X receptor
steroidogenesis
cytochrome P450
drug resistance
備考
特別依頼原稿
発行日
2005-01-31
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
116巻
3号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
215
終了ページ
220
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/116/3/116_3_215/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
参考文献
1) Kliewer SA, Moore JT, Wade L, Staudinger JL, Watson MA, Jones SA, Mckee DD, Oliver BB, Willson TM, Zetterstrom RH, Perlmann T and Lehmann JM: An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway. Cell (1998) 92, 73-82.
2) Lehmann JM, Mckee DD, Watson MA, Willson TM, Moore JT and Kliewer SA: The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J Clin Invest (1998) 102, 1016-1023.
3) Bertilsson G, Heidrich J, Svensson K, Asman M, Jendeberg L, Sydow-Backman M, Ohlsson R, Postlind H, Blomquist P and Berkenstam A: Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction. Proc Natl Acad Sci USA (1998) 95, 12208-12213.
4) Zhang H, LeCulyse E, Liu L, Hu M, Matoney L, Zhu W and Yan B: Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation. Arch Biochem Biophys (1999) 368, 14-22.
5) Blumberg B, Sabbagh W Jr, Juguilon H, Bolado J Jr, van Meter CM, Ong ES and Evans RM: SXR, a novel steroid and xenobiotic-sensing nuclear receptor. Genes Dev (1998) 12, 3195-3205.
6) Pascussi JM, Jounaidi Y, Drocourt L, Domergue J, Balabaud C, Maurel P and Vilarem MJ: Evidence for the presence of a functional pregnane X receptor response element in the CYP3A7 promoter gene. Biochem Biophys Res Commun (1999) 260, 377-381.
7) Watkins RE, Wisely GB, Moore LB, Collins JL, Lambert MH, Williams SP, Willson TM, Kliewer SA and Redinbo MR: The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity. Science (2001) 292, 2329-2333.
8) Masuyama H, Hiramatsu Y, Mizutani H, Inoshita H and Kudo T: The expression of pregnane X receptor and its target gene, cytochrome P450 3A1, in perinatal mouse. Mol Cell Endocrinol (2001) 172, 47-56.
9) Mangelsdorf DJ and Evans RM: The RXR heterodimers and orphan receptors. Cell (1995) 83, 841-850.
10) Horwitz KB, Jackson TA, Bain DL, Richer JK, Takimoto GS and Tung L: Nuclear receptor coactivators and corepressors. Mol Endocrinol (1996) 10, 1167-1177.
11) Masuyama H, Brownfield C, St-Arnaud R and MacDonald P: Evidence for ligand-dependent intramolecular folding of the AF-2 domain in vitamin D receptor-activated transcription and coactivator interaction. Mol Endocrinol (1997) 11, 1507-1517.
12) Onate SA, Tsai SY, Tsai M-J and O'Malley BW: Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science (1995) 270, 1354-1357.
13) Cavailles V, Dauvois S, L'Horset F, Lopez G, Hoare S, Kushner PJ and Parker MG: Nuclear factor RIP 140 modulates transcriptional activation by the estrogen receptor. EMBO J (1995) 14, 3741-3751.
14) Jones SA, Moore LB, Shenk JL, Wisely GB, Hamilton GA, McKee DD, Tomkinson NC, LeCluyse EL, Lambert MH, Willson TM, Kliewer SA and Moore JT: The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution. Mol Endocrinol (2000) 14, 27-39.
15) Masuyama H, Hiramatsu Y, Kunitomi M, Kudo T and MacDonald PN: Endocrine Disrupting Chemicals Phthalic Acid and Nonylphenol Activate Pregnane X Receptor-mediated Transcription. Mol Endocrinol (2000) 14, 421-428.
16) Xie W, Radominska-Pandya A, Shi Y, Simon CM, Nelson MC, Ong ES, Waxman DJ and Evans RM: An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proc Natl Acad Sci USA (2001) 98, 3375-3380.
17) Staudinger JL, Goodwin B, Jones SA, Hawkins-Brown D, MacKenzie KI, LaTour A, Liu Y, Klaassen CD, Brown KK, Reinhard J, Willson TM, Koller BH and Kliewer SA: The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Proc Natl Acad Sci USA (2001) 98, 3369-3374.
18) Goodwin B, Moore LB, Stoltz CM, McKee DD and Kliewer SA: Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor. Mol Pharmacol (2001) 60, 427-431.
19) Falkner KC, Pinaire JA, Xiao GH, Geoghegan TE and Prough RA: Regulation of the rat glutathione S-transferase A2 gene by glucocorticoids: involvement of both the glucocorticoid and pregnane X receptors. Mol Pharmacol (2001) 60, 611-619.
20) Masuyama H, Kodama J, Hiramatsu Y and Kudo T: Expression and Potential Roles of pregnane X receptor in Endometrial cancer. J Clin Endocrinol Metab (2003) 88, 4446-4454.
21) Sasano H and Harada N: Intratumoral aromatase in human breast, endometrial, and ovarian malignancies. Endocr Rev (1998) 19, 593-607.
22) Radominska A, Treat S and Little J: Bile acid metabolism and the pathophysiology of cholestasis. Semin Liver Dis (1993) 13, 219-234.
23) Synold TW, Dussault I and Forman BM: The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nature Med (2001) 7, 584-590.
24) Masuyama H and MacDonald PN: Proteasome-mediated degradation of the vitamin D receptor (VDR) and a putative role for SUG1 interaction with the Af-2 domain of VDR. J Cell Biochem (1998) 71, 429-440.
25) Masuyama H and Hiramatsu Y: Involvement of suppressor for gal-1 in the ubiquitin/proteasome-mediated degradation of estrogen receptors. J Biol Chem (2004) 279, 12020-12026.
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言語
Japanese
OAI-PMH Set
岡山大学
著作権者
Copyright© 岡山医学会
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publisher
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