| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Sekito, Takanori| Wada, Koichiro| Ishii, Ayano| Iwata, Takehiro| Matsubara, Takehiro| Tomida, Shuta| Watanabe, Masami| Araki, Motoo| Sadahira, Takuya| |
| キーワード | cystitis vagina microbiota Lactobacillus urinary tract infection |
| 発行日 | 2023-05-18 |
| 出版物タイトル | Frontiers in Microbiology |
| 巻 | 14巻 |
| 出版者 | Frontiers Media |
| 開始ページ | 1187479 |
| ISSN | 1664-302X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 Sekito, Wada, Ishii, Iwata, Matsubara, Tomida, Watanabe, Araki and Sadahira. |
| 論文のバージョン | publisher |
| PubMed ID | 37275169 |
| DOI | 10.3389/fmicb.2023.1187479 |
| Web of Science KeyUT | 000998008400001 |
| 関連URL | isVersionOf https://doi.org/10.3389/fmicb.2023.1187479 |
| JaLCDOI | 10.18926/AMO/62820 |
|---|---|
| フルテキストURL | 75_6_763.pdf |
| 著者 | Iwata, Takehiro| Sadahira, Takuya| Maruyama, Yuki| Sekito, Takanori| Yoshinaga, Kasumi| Watari, Shogo| Nagao, Kentaro| Kawada, Tatsushi| Tominaga, Yusuke| Nishimura, Shingo| Takamoto, Atsushi| Sako, Tomoko| Edamura, Kohei| Kobayashi, Yasuyuki| Araki, Motoo| Ishii, Ayano| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| Wada, Koichiro| |
| 抄録 | The aim of this ongoing trial is to evaluate the clinical efficacy and safety of sitafloxacin (STFX) 200 mg once daily (QD) for 7 days in patients with refractory genitourinary tract infections, which include recurrent or complicated cystitis, complicated pyelonephritis, bacterial prostatitis, and epididymitis. The primary endpoint is the microbiological efficacy at 5-9 days after the last administration of STFX. Recruitment began in February 2021, and the target total sample size is 92 participants. |
| キーワード | genitourinary tract infections fluoroquinolone resistance extended-spectrum beta-lactamase |
| Amo Type | Clinical Study Protocol |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-12 |
| 巻 | 75巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 763 |
| 終了ページ | 766 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34955548 |
| Web of Science KeyUT | 000735319800006 |
| NAID | 120007180272 |
| JaLCDOI | 10.18926/AMO/54508 |
|---|---|
| フルテキストURL | 70_4_299.pdf |
| 著者 | Wada, Koichiro| Uehara, Shinya| Ishii, Ayano| Sadahira, Takuya| Yamamoto, Masumi| Mitsuhata, Ritsuko| Takamoto , Atsushi| Araki, Motoo| Kobayashi, Yasuyuki| Watanabe, Masami| Watanabe, Toyohiko| Hotta, Katsuyuki| Nasu, Yasutomo| |
| 抄録 | Urinary tract infections (UTIs) are the most common bacterial infections in women, and many patients experience frequent recurrence. The aim of this report is to introduce an on-going prospective phase II clinical trial performed to evaluate the preventive effectiveness of Lactobacillus vaginal suppositories for prevention of recurrent cystitis. Patients enrolled in this study are administered vaginal suppositories containing the GAI 98322 strain of Lactobacillus crispatus every 2 days or 3 times a week for one year. The primary endpoint is recurrence of cystitis and the secondary endpoints are adverse events. Recruitment began in December 2013 and target sample size is 20 participants. |
| キーワード | probiotics lactobacilli Lactobacillus crispatus urinary tract infection vaginal suppository |
| Amo Type | Clinical Study Protocols |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-08 |
| 巻 | 70巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 299 |
| 終了ページ | 302 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27549677 |
| Web of Science KeyUT | 000384748600012 |
| JaLCDOI | 10.18926/AMO/52405 |
|---|---|
| フルテキストURL | 68_2_89.pdf |
| 著者 | Sako, Shinichi| Kariyama, Reiko| Mitsuhata, Ritsuko| Yamamoto, Masumi| Wada, Koichiro| Ishii, Ayano| Uehara, Shinya| Kokeguchi, Susumu| Kusano, Nobuchika| Kumon, Hiromi| |
| 抄録 | We conducted a study on molecular epidemiology and clinical implications of metallo-β-lactamase (MBL)-producing Pseudomonas aeruginosa isolated from urine. Over a 10-year period from 2001 through 2010, a total of 92 MBL-producing P. aeruginosa urine isolates were collected from patients (one isolate per patient) who were admitted to 5 hospitals in Okayama Prefecture, Japan. When cross-infection was suspected in the hospital, pulsed-field gel electrophoresis was performed. In the resulting dendrogram of 79 MBL-producing P. aeruginosa urine isolates, no identical isolates and 7 pairs of isolates with ≥80% similarity were found. The biofilm-forming capabilities of 92 MBL-producing P. aeruginosa urine isolates were significantly greater than those of 92 non-MBL-producing urine isolates in a medium of modified artificial urine. The imipenem resistance transferred in 16 of 18 isolates tested, and these frequencies were in the range of 10－3 to 10－9. All of 18 isolates tested belonged to internationally spread sequence type 235 and had 3 gene cassettes of antimicrobial resistance genes in the class 1 integron. The strong biofilm-forming capabilities of MBL-producing P. aeruginosa urine isolates could be seriously implicated in nosocomial infections. To prevent spread of the organism and transferable genes, effective strategies to inhibit biofilm formation in medical settings are needed. |
| キーワード | Pseudomonas aeruginosa metallo-β-lactamase molecular epidemiology biofilm urinary tract infection |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-04 |
| 巻 | 68巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 89 |
| 終了ページ | 99 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24743784 |
| Web of Science KeyUT | 000334652700004 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/52504 |
| JaLCDOI | 10.18926/AMO/48078 |
|---|---|
| フルテキストURL | 66_1_23.pdf |
| 著者 | Watanabe, Toyohiko| Inoue, Miyabi| Ishii, Ayano| Yamato, Toyoko| Yamamoto, Masumi| Sasaki, Katsumi| Kobayashi, Yasuyuki| Araki, Motoo| Uehara, Shinya| Saika, Takashi| Kumon, Hiromi| |
| 抄録 | Polypropylene mesh implants for the correction of pelvic organ prolapse (POP) are now available in Japan. We developed an innovative approach for correcting POP by placing polypropylene mesh transvaginally with laparoscopic assistance. From June 2007 through March 2010, sixteen consecutive patients with symptomatic stage 2 or 3 pelvic organ prolapse underwent the laparoscopic-assisted tension-free vaginal mesh procedure at Okayama University Hospital. All patients were evaluated before and at 1, 3, 6, and 12 months after surgery. Female sexual function was also evaluated with the Female Sexual Function Index (FSFI). The procedure was performed successfully without significant complications. Fifteen of 16 patients were considered anatomically cured (93.8%) at 12 months postoperatively. One patient with a recurrent stage 3 vaginal vault prolapse required sacral colpopexy six months postoperatively. Total FSFI scores improved significantly from 10.3±1.3 at baseline to 18.0±1.2 at 12 months after surgery. The laparoscopic-assisted trans-vaginal mesh is a safe, effective, and simple procedure for POP repairs. The procedure not only restores anatomic relationships but also improves sexual function. |
| キーワード | tension-free vaginal mesh pelvic organ prolapse laparoscopic female urology sexual function |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2012-02 |
| 巻 | 66巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 23 |
| 終了ページ | 29 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2012 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 22358136 |
| Web of Science KeyUT | 000300800700004 |
| 著者 | 石井 亜矢乃| |
|---|---|
| 発行日 | 2001-04-28 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 113巻 |
| 号 | 1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 石井 亜矢乃| |
|---|---|
| 発行日 | 2001-03-25 |
| 出版物タイトル | |
| 資料タイプ | 学位論文 |