JaLCDOI 10.18926/AMO/57377
フルテキストURL 73_5_457.pdf
著者 Iwamuro, Masaya| Takahara, Masahiro| Yamazaki, Tatsuhiro| Tanaka, Takehiro| Kondo, Yoshitaka| Hiraoka, Sakiko| Okada, Hiroyuki|
抄録 A 60-year-old Caucasian male was diagnosed with lung adenocarcinoma and multiple metastases to the bone, spleen, and brain. He underwent radiotherapy for the brain and lumbar spine metastases, plus chemotherapy (cisplatin and pemetrexed). The chemotherapy was discontinued due to vomiting and hyponatremia, and nivolumab was then administered. Eight months later, 18F-fluorodeoxyglucose positron emission tomography showed tracer uptake in the colon. Colonoscopy revealed a reddish multinodular polyp in the sigmoid colon. The polyp showed irregular microvessels. No colonic mucosal surface structures were observed. Colonic metastasis of the lung carcinoma was highly suspected; the polyp was therefore surgically removed. The histological analysis revealed granulation tissue and suppurative inflammation without neoplastic changes. We diagnosed the lesion as a granulation polyp. Despite the difficulty in diagnosing these lesions due to their rarity and similarity to metastatic colon tumors, we suggest that recognizing the endoscopic features of the polyp surface may allow a preoperative diagnosis.
キーワード colonoscopy colonic neoplasms granulation polyp
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2019-10
73巻
5号
出版者 Okayama University Medical School
開始ページ 457
終了ページ 461
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 31649373
Web of Science KeyUT 000491886600012
フルテキストURL fulltext.pdf
著者 Iwamuro, Masaya| Takahashi, Takahide| Tanaka, Takehiro| Toji, Tomohiro| Hiraoka, Sakiko| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki|
発行日 2020-10-07
出版物タイトル Case Reports in Gastrointestinal Medicine
2020巻
出版者 Hindawi
開始ページ 8893604
ISSN 2090-6528
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 Masaya Iwamuro et al.
論文のバージョン publisher
PubMed ID 33083067
DOI 10.1155/2020/8893604
Web of Science KeyUT 000583201400001
関連URL isVersionOf https://doi.org/10.1155/2020/8893604
フルテキストURL SR9_1_11934.pdf
著者 Takahara, Masahiro| Takaki, Akinobu| Hiraoka, Sakiko| Adach, Takuya| Shimomura, Yasuyuki| Matsushita, Hiroshi| Nguyen Tien Thi Thuy| Koike, Kazuko| Ikeda, Airi| Takashima, Shiho| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Sugihara, Yusaku| Harada, Keita| Eikawa, Shingo| Morita, Hidetoshi| Udono, Heiichiro| Okada, Hiroyuki|
発行日 2019-8-15
出版物タイトル Scientific Reports
9巻
出版者 Nature Publishing Group
開始ページ 11934
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2019
論文のバージョン publisher
PubMed ID 31417110
DOI 10.1038/s41598-019-48331-w
Web of Science KeyUT 000480680800048
関連URL isVersionOf https://doi.org/10.1038/s41598-019-48331-w
JaLCDOI 10.18926/AMO/53912
フルテキストURL 69_6_365.pdf
著者 Kawano, Seiji| Hiraoka, Sakiko| Okada, Hiroyuki| Akita, Mitsuhiro| Iwamuro, Masaya| Yamamoto, Kazuhide|
抄録 Several studies have identified a relationship between myelodysplastic syndrome and Behçetʼs disease (BD), especially intestinal BD, and trisomy 8 appears to play an important role in these disorders. Despite this, only few case reports or series have been reported in gastroenterology, meaning that endoscopic findings and characteristics of intestinal BD have not been clarified yet. In this report, we describe three cases of intestinal BD associated with myelodysplastic syndrome and trisomy 8, and discuss the clinical features and problems of these disorders from a gastroenterology perspective.
キーワード Behçetʼs disease trisomy 8 myelodysplastic syndrome
Amo Type Case Reports
出版物タイトル Acta Medica Okayama
発行日 2015-12
69巻
6号
出版者 Okayama University Medical School
開始ページ 365
終了ページ 369
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 26690248
Web of Science KeyUT 000368434500007
フルテキストURL fulltext.pdf
著者 Iwamuro, Masaya| Tanaka, Takehiro| Yamauchi, Nao| Nakashima, Yuri| Wada, Takahira| Hiraoka, Sakiko| Kawahara, Yoshiro| Okada, Hiroyuki|
キーワード cytomegalovirus colitis pseudolipomatosis gastric emphysema post-resuscitation diabetes mellitus
発行日 2020-02-15
出版物タイトル Internal Medicine
59巻
4号
出版者 The Japanese Society of Internal Medicine
開始ページ 519
終了ページ 525
ISSN 0918-2918
NCID AA10827774
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 by The Japanese Society of Internal Medicine
論文のバージョン publisher
PubMed ID 31645533
NAID 130007798412
DOI 10.2169/internalmedicine.3633-19
Web of Science KeyUT 000516549400009
関連URL isVersionOf https://doi.org/10.2169/internalmedicine.3633-19
著者 Saito, Shunsuke| Kato, Jun| Hiraoka, Sakiko| Horii, Joichiro| Suzuki, Hideyuki| Higashi, Reiji| Kaji, Eisuke| Kondo, Yoshitaka| Yamamoto, Kazuhide|
発行日 2011-09
出版物タイトル Inflammatory Bowel Diseases
17巻
9号
資料タイプ 学術雑誌論文
著者 Hirakawa, Tomoko| Kato, Jun| Okumura, Yoshihiro| Hori, Keisuke| Takahashi, Sakuma| Suzuki, Hideyuki| Akita, Mitsuhiro| Higashi, Reiji| Saito, Shunsuke| Kaji, Eisuke| Uraoka, Toshio| Hiraoka, Sakiko| Yamamoto, Kazuhide|
発行日 2012-02
出版物タイトル Journal of Gastroenterology
47巻
2号
資料タイプ 学術雑誌論文
フルテキストURL fulltext.pdf
著者 Iwamuro, Masaya| Takahashi, Takahide| Watanabe, Natsuki| Tanaka, Takehiro| Inokuchi, Toshihiro| Hiraoka, Sakiko| Otsuka, Fumio| Okada, Hiroyuki|
キーワード central memory T cell flow cytometry natural killer T cells peripheral blood mononuclear cell ulcerative colitis
発行日 2022-01-12
出版物タイトル International Journal of Immunopathology and Pharmacology
36巻
出版者 Sage Publications Inc.
開始ページ 1
終了ページ 12
ISSN 0394-6320
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2022
論文のバージョン publisher
PubMed ID 35021918
DOI 10.1177/20587384211051982
Web of Science KeyUT 000747491200001
関連URL isVersionOf https://doi.org/10.1177/20587384211051982
JaLCDOI 10.18926/AMO/60363
フルテキストURL 74_4_265.pdf
著者 Inokuchi, Toshihiro| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahar, Masahiro| Kawano, Seiji| Harada, Keita| Okada, Hiroyuki| Kato, Jun|
抄録 Determining factors that predict a favorable disease course without anti-tumor necrosis factor (TNF) agents would help establish a more cost-effective strategy for Crohn’s disease (CD). A retrospective chart review was performed for CD patients with disease durations > 10 years who had not received anti-TNF agents as first-line therapy. Patients were divided into 2 groups: those who received neither anti-TNF agents nor bowel resection (G1), and those who had received an anti-TNF agent and/or bowel resection (G2). The patient backgrounds, therapies and clinical courses were compared between the groups. A total of 62 CD patients met the inclusion criteria (males: 71%; median duration of follow-up: 19 years). Six patients were included in G1; they were significantly less likely to have upper gastrointestinal lesions than G2 (p=0.007). A multivariate analysis revealed that the significant factors for avoidance of bowel resection without anti-TNF treatment were non-stricturing and non-penetrating behaviors, and absence of upper gastrointestinal lesions at the diagnosis (hazard ratios 0.41 and 0.52; p=0.004 and 0.04, respectively). In consideration of the long treatment course of CD, patients with non-stricturing and non-penetrating behaviors and no upper gastrointestinal lesions should not be treated with anti-TNF agents as first-line therapy.
キーワード Crohn’s disease anti-TNF agent upper gastrointestinal lesion bamboo joint-like appearance
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2020-08
74巻
4号
出版者 Okayama University Medical School
開始ページ 265
終了ページ 274
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32843757
Web of Science KeyUT 000562508700001
NAID 120006880202
フルテキストURL fulltext.pdf
著者 Yamamoto, Shumpei| Kinugasa, Hideaki| Yamasaki, Yasushi| Hirai, Mami| Ako, Soichiro| Takei, Kensuke| Igawa, Shoko| Yasutomi, Eriko| Oka, Shohei| Ohmori, Masayasu| Inokuchi, Toshihiro| Harada, Keita| Hiraoka, Sakiko| Nouso, Kazuhiro| Tanaka, Takehiro| Okada, Hiroyuki|
キーワード colorectal ESD PECS electrocoagulation syndrome immunosuppressants and steroids post-ESD fever
発行日 2021-12-09
出版物タイトル DEN Open
2巻
1号
出版者 Wiley
開始ページ e83
ISSN 2692-4609
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 The Authors.
論文のバージョン publisher
PubMed ID 35310725
DOI 10.1002/deo2.83
Web of Science KeyUT 001047024900091
関連URL isVersionOf https://doi.org/10.1002/deo2.83
JaLCDOI 10.18926/AMO/51864
フルテキストURL 67_5_285.pdf
著者 Akita, Mitsuhiro| Hiraoka, Sakiko| Kaji, Eisuke| Takemoto, Koji| Nagahara, Yasuhiro| Yamamoto, Hiroshi| Yamamoto, Kazuhide| Kato, Jun|
抄録 Whether presence or history of extracolonic primary malignancy is a risk for colorectal neoplasia is not fully known. In this study, 26,452 first-time colonoscopy cases were examined using a colonoscopy database. Among the analyzed subjects, 3,026 (11%) subjects had history or concomitance of extracolonic primary malignancy, while the remaining 23,426 subjects did not. Colorectal neoplasia was observed in 39% of all the subjects. A crude comparison showed that the prevalence of any type of colorectal neoplasia was higher in subjects with extracolonic malignancy than in those without (42% vs. 39%, p=0.0012). However, after adjusting for confounding factors, the odds ratios (ORs) of subjects with extracolonic malignancy for having colorectal neoplasia, advanced neoplasia, and cancer were all less than 1.0, and all significantly different from those of subjects without extracolonic malignancy. Analysis according to the type of extracolonic malignancy revealed that gastric cancer cases had a significantly lower risk for colorectal advanced neoplasia (OR:0.81;95% CI:0.67-0.99). Among major malignancies, only esophageal squamous cell cancer cases had increased risk for colorectal neoplasia (OR:1.66;95% CI:1.20-2.29). Patients with presence or history of extracolonic malignancy did not carry a higher risk of occurrence of colorectal neoplasia.
キーワード colorectal cancer colonoscopy risk factor database
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2013-10
67巻
5号
出版者 Okayama University Medical School
開始ページ 285
終了ページ 292
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24145728
Web of Science KeyUT 000325836100002
フルテキストURL fulltext.pdf
著者 Yasutomi, Eriko| Inokuchi, Toshihiro| Hiraoka, Sakiko| Takei, Kensuke| Igawa, Shoko| Yamamoto, Shumpei| Ohmori, Masayasu| Oka, Shohei| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahara, Masahiro| Harada, Keita| Furukawa, Masaki| Itoshima, Kouichi| Okada, Ken| Otsuka, Fumio| Tanaka, Takehiro| Mitsuhashi, Toshiharu| Kato, Jun| Okada, Hiroyuki|
発行日 2021-05-27
出版物タイトル Scientific Reports
11巻
1号
出版者 Nature Research
開始ページ 11086
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2021
論文のバージョン publisher
PubMed ID 34045529
NAID 120007089817
DOI 10.1038/s41598-021-90441-x
Web of Science KeyUT 000658389400001
関連URL isVersionOf https://doi.org/10.1038/s41598-021-90441-x
フルテキストURL fulltext.pdf
著者 Kinugasa, Hideaki| Hiraoka, Sakiko| Nouso, Kazuhiro| Yamamoto, Shumpei| Hirai, Mami| Terasawa, Hiroyuki| Yasutomi, Eriko| Oka, Shohei| Ohmori, Masayasu| Yamasaki, Yasushi| Inokuchi, Toshihiro| Takahara, Masahiro| Harada, Keita| Tanaka, Takehiro| Okada, Hiroyuki|
キーワード IBD-associated neoplasia IBD-associated cancer Liquid biopsy ctDNA
発行日 2020-12-03
出版物タイトル BMC Cancer
20巻
1号
出版者 BMC
開始ページ 1188
ISSN 1471-2407
NCID AA12034763
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s). 2020
論文のバージョン publisher
PubMed ID 33272240
DOI 10.1186/s12885-020-07699-z
Web of Science KeyUT 000597268700004
関連URL isVersionOf https://doi.org/10.1186/s12885-020-07699-z
フルテキストURL fulltext.pdf
著者 Sugihara, Yuusaku| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Morito, Yuki| Takahashi, Sakuma| Harada, Keita| Tanaka, Takehiro| Otsuka, Fumio| Okada, Hiroyuki|
キーワード graft-vs.-host disease terminal ileum allo-hematopoietic stem cell transplantation villous atrophy endoscopy
発行日 2020-02-21
出版物タイトル Experimental and Therapeutic Medicine
19巻
4号
出版者 Spandidos Publications
開始ページ 3076
終了ページ 3080
ISSN 1792-0981
NCID AA12610820
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © Sugiharaet al.
論文のバージョン publisher
PubMed ID 32256795
DOI 10.3892/etm.2020.8538
Web of Science KeyUT 000523637100082
関連URL isVersionOf https://doi.org/10.3892/etm.2020.8538
フルテキストURL fulltext.pdf
著者 Yasutomi, Eriko| Hiraoka, Sakiko| Yamamoto, Shumpei| Oka, Shohei| Hirai, Mami| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Harada, Keita| Kato, Jun| Okada, Hiroyuki|
キーワード ulcerative colitis salicylates mesalazine sulfasalazine
発行日 2019-12-02
出版物タイトル Journal of Clinical Medicine
8巻
12号
出版者 MDPI
ISSN 2077-0383
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2019 by the authors.
論文のバージョン publisher
PubMed ID 31810227
DOI 10.3390/jcm8122109
Web of Science KeyUT 000506640400082
関連URL isVersionOf https://doi.org/10.3390/jcm8122109
フルテキストURL fulltext.pdf
著者 Takahara, Masahiro| Hiraoka, Sakiko| Ohmori, Masayasu| Takeuchi, Keiko| Takei, Kensuke| Yasutomi, Eriko| Igawa, Shoko| Yamamoto, Shumpei| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Harada, Keita| Ohnishi, Hideki| Okada, Hiroyuki|
キーワード bowel wall thickness Mayo endoscopic subscore classification transabdominal ultrasonography ulcerative colitis
発行日 2022-09-15
出版物タイトル Internal Medicine
61巻
18号
出版者 The Japanese Society of Internal Medicine
開始ページ 2703
終了ページ 2709
ISSN 0918-2918
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2022 The Japanese Society of Internal Medicine
論文のバージョン publisher
PubMed ID 35185047
DOI 10.2169/internalmedicine.8827-21
Web of Science KeyUT 000857218300001
関連URL isVersionOf https://doi.org/10.2169/internalmedicine.8827-21
JaLCDOI 10.18926/AMO/55436
フルテキストURL 71_5_391.pdf
著者 Iwamuro, Masaya| Takata, Katsuyoshi| Hayashi, Eiko| Kawano, Seiji| Hiraoka, Sakiko| Kawahara, Yoshiro| Yoshino, Tadashi| Okada, Hiroyuki|
抄録  To evaluate the usefulness of colonoscopy for the detection of ileal involvement in patients with intestinal follicular lymphoma, seventeen patients with intestinal follicular lymphoma who underwent colonoscopy and biopsy sampling from the terminal ileum were enrolled. The patients were divided into 2 groups: cases with ileal involvement (n=6) and cases without ileal involvement (n=11). Patients’ clinical backgrounds were compared between the two groups. Subsequently, 10 board-certified endoscopists independently evaluated the endoscopic pictures and determined whether the ileum was involved with follicular lymphoma. Infiltration of follicular lymphoma cells were identified in 6 patients (35.3%). Cases with positive ileal involvement were diagnosed with follicular lymphoma at a younger age than were cases without ileal involvement (55.4±7.4 vs. 68.1±10.3 years, p=0.011). Macroscopically, in patients with ileal involvement, there were multiple polypoid elevations smaller than 5 mm in 4 cases, single polypoid elevation smaller than 5 mm in 1 case, and single polypoid elevation larger than 5 mm in 1 case. In patients without ileal involvement, there were no lesions in the terminal ileum in 7 cases, and multiple polypoid elevations smaller than 5 mm were seen in 4 cases. The accuracy of the macroscopic evaluation by 10 board-certified endoscopists was 68.8%. Colonoscopy is particularly recommended during the initial workup of patients with follicular lymphoma diagnosed at age ≤ 60 years. The diagnosis of ileal involvement based on morphology alone is difficult; thus, biopsy and pathologic diagnosis are required for accurate diagnosis.
キーワード follicular lymphoma colonoscopy ileal neoplasms terminal ileum small intestine
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2017-10
71巻
5号
出版者 Okayama University Medical School
開始ページ 391
終了ページ 398
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29042696
フルテキストURL fulltext.pdf
著者 Hiraoka, Sakiko| Takashima, Shiho| Inokuchi, Toshihiro| Nakarai, Asuka| Takahara, Masahiro| Harada, Keita| Seki, Yasuhiro| Watanabe, Katsunori| Kato, Jun| Okada, Hiroyuki|
キーワード Colitis ulcerative Fecal calprotectin Quantitative fecal immunochemical test Latex agglutination turbidimetric immunoassay Mucosal healing
発行日 2018-12-14
出版物タイトル Intestinal Research
17巻
2号
出版者 Korean Association for the Study of Intestinal Diseases
開始ページ 202
終了ページ 209
ISSN 1598-9100
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © Copyright 2019. Korean Association for the Study of Intestinal Diseases
論文のバージョン publisher
PubMed ID 30541228
DOI 10.5217/ir.2018.00086
Web of Science KeyUT 000466136800006
関連URL isVersionOf https://doi.org/10.5217/ir.2018.00086
フルテキストURL fulltext.pdf
著者 Iwamuro, Masaya| Tanaka, Takehiro| Sugihara, Yuusaku| Harada, Keita| Hiraoka, Sakiko| Kondo, Yoshitaka| Okada, Hiroyuki|
キーワード endometriosis subepithelial lesion submucosal tumor cecum colonoscopy
発行日 2021
出版物タイトル Internal Medicine
60巻
11号
出版者 Japanese Society of Internal Medicine
開始ページ 1697
終了ページ 1701
ISSN 0918-2918
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 The Japanese Society of Internal Medicine
論文のバージョン publisher
PubMed ID 33390498
DOI 10.2169/internalmedicine.6418-20
Web of Science KeyUT 000659353300007
関連URL isVersionOf https://doi.org/10.2169/internalmedicine.6418-20
JaLCDOI 10.18926/AMO/66674
フルテキストURL 78_1_079.pdf
著者 Takahara, Masahiro| Hiraoka, Sakiko| Ohmori, Masayasu| Takeuchi, Keiko| Takei, Kensuke| Aoyama, Yuki| Yasutomi, Eriko| Igawa, Shoko| Inokuchi, Toshihiro| Toyosawa, Junki| Yamasaki, Yasushi| Kinugasa, Hideaki| Harada, Keita| Onishi, Hideki| Okada, Hiroyuki|
抄録 This study examined the utility of the combined use of transabdominal ultrasonography (TUS) and fecal immunochemical testing (FIT) to detect mucosal inflammation, vis-a-vis the Mayo endoscopic subscore (MES), in ulcerative colitis (UC). Sixty-three UC patients who underwent TUS and FIT were retrospectively enrolled. For TUS, the colon was divided into five segments, and the bowel wall thickness was measured and evaluated. The accuracy of FIT (> 100 ng/ml) in detecting mucosal inflammation (MES>0) was 0.93, whereas that of TUS (BWT>2 mm) in each segment was 0.84-0.97. The combined use of TUS and FIT may be helpful in noninvasive treatment strategies.
キーワード transabdominal ultrasonography fecal immunochemical test ulcerative colitis Mayo endoscopic subscore
Amo Type Short Communication
出版物タイトル Acta Medica Okayama
発行日 2024-02
78巻
1号
出版者 Okayama University Medical School
開始ページ 79
終了ページ 83
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り