著者 久富 美紀|
発行日 2008-03-25
出版物タイトル
資料タイプ 学位論文
著者 Yanagi, Yoshinobu| Fujita, Mariko| Hisatomi, Miki| Matsuzaki, Hidenobu| Konouchi, Hironobu| Katase, Naoki| Nagatsuka, Hitoshi| Asaumi, Jun-ichi|
発行日 201012
出版物タイトル Oral Radiology
26巻
2号
資料タイプ 学術雑誌論文
著者 Asaumi, Jun-ichi| Yanagi, Yoshinobu| Konouchi, Hironobu| Hisatomi, Miki| Matsuzaki, Hidenobu| Kishi, Kanji|
発行日 2004-7
出版物タイトル Oral Oncology
40巻
6号
資料タイプ 学術雑誌論文
著者 Hisatomi, Miki| Yanagi, Yoshinobu| Konouchi, Hironobu| Matsuzaki, Hidenobu| Takenobu, Toshihiko| Unetsubo, Teruhisa| Asaumi, Jun-ichi|
発行日 2011-02
出版物タイトル Oral Oncology
47巻
2号
資料タイプ 学術雑誌論文
著者 Asaumi, Jun-ichi| Yanagi, Yoshinobu| Konouchi, Hironobu| Hisatomi, Miki| Matsuzaki, Hidenobu| Shigehara, Hiroshi| Kishi, Kanji|
発行日 2004-9
出版物タイトル European Journal of Radiology
51巻
3号
資料タイプ 学術雑誌論文
フルテキストURL isd-49-27.pdf
著者 Bamgbose, Babatunde O.| Okada, Shunsuke| Hisatomi, Miki| Yanagi, Yoshinobu| Takeshita, Yohei| Abdu, Zahrau Saleh| Ekuase, Edugie J.| Asaumi, Jun-ichi|
キーワード Tooth Supernumerary Odontoma Odontogenic Cyst
発行日 2019-05-25
出版物タイトル Imagining Science in Dentistry
49巻
1号
出版者 Korean Academy of Oral and Maxillofacial Radiology
開始ページ 27
終了ページ 34
ISSN 22337822
NCID AA12764256
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2019 by Korean Academy of Oral and Maxillofacial Radiology
論文のバージョン publisher
PubMed ID 30941285
DOI 10.5624/isd.2019.49.1.27
Web of Science KeyUT 000462925200004
関連URL isVersionOf https://doi.org/10.5624/isd.2019.49.1.27
フルテキストURL fulltext20230828-03.pdf
著者 Al‑Hammad, Wlla| Fujikura, Mamiko| Hisatomi, Miki| Okada, Shunsuke| Munhoz, Luciana| Kawazu, Toshiyuki| Takeshita, Yohei| Fujita, Mariko| Yanagi, Yoshinobu| Asaumi, Jun-Ichi|
キーワード vascular anomalies magnetic resonance imaging computed tomography dynamic contrast-enhanced magnetic resonance imaging contrast index curve
発行日 2023-07-27
出版物タイトル Oncology Letters
26巻
3号
出版者 Spandidos Publications
開始ページ 394
ISSN 1792-1074
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 Al-Hammad et al.
論文のバージョン publisher
PubMed ID 37600333
DOI 10.3892/ol.2023.13980
Web of Science KeyUT 001049518700001
関連URL isVersionOf https://doi.org/10.3892/ol.2023.13980
JaLCDOI 10.18926/AMO/52009
フルテキストURL 67_6_359.pdf
著者 Katashima, Kazunori| Kuroda, Masahiro| Ashida, Masakazu| Sasaki, Takanori| Taguchi, Takehito| Matsuzaki, Hidenobu| Murakami, Jun| Yanagi, Yoshinobu| Hisatomi, Miki| Hara, Marina| Kato, Hirokazu| Ohmura, Yuichi| Kobayashi, Tomoki| Kanazawa, Susumu| Harada, Sosuke| Takemoto, Mitsuhiro| Ohno, Seiichiro| Mimura, Seiichi| Asaumi, Junichi|
抄録 It is well known that many tumor tissues show lower apparent diffusion coefficient (ADC) values, and that several factors are involved in the reduction of ADC values. The aim of this study was to clarify how much each factor contributes to decreases in ADC values. We investigate the roles of cell density, extracellular space, intracellular factors, apoptosis and necrosis in ADC values using bio-phantoms. The ADC values of bio-phantoms, in which Jurkat cells were encapsulated by gellan gum, were measured by a 1.5-Tesla magnetic resonance imaging device with constant diffusion time of 30sec. Heating at 42℃ was used to induce apoptosis while heating at 48℃ was used to induce necrosis. Cell death after heating was evaluated by flow cytometric analysis and electron microscopy. The ADC values of bio-phantoms including non-heated cells decreased linearly with increases in cell density, and showed a steep decline when the distance between cells became less than 3μm. The analysis of ADC values of cells after destruction of cellular structures by sonication suggested that approximately two-thirds of the ADC values of cells originate from their cellular structures. The ADC values of bio-phantoms including necrotic cells increased while those including apoptotic cells decreased. This study quantitatively clarified the role of the cellular factors and the extracellular space in determining the ADC values produced by tumor cells. The intermediate diffusion time of 30msec might be optimal to distinguish between apoptosis and necrosis.
キーワード ADC apoptosis necrosis hyperthermia cell density
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2013-12
67巻
6号
出版者 Okayama University Medical School
開始ページ 359
終了ページ 367
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24356720
Web of Science KeyUT 000328915700004
フルテキストURL fulltext20240226-01.pdf
著者 Kawazu, Toshiyuki| Takeshita, Yohei| Fujikura, Mamiko| Okada, Shunsuke| Hisatomi, Miki| Asaumi, Junichi|
キーワード Deep neural networks Caries detection Domain-Specific transfer learning Panoramic tomography
備考 The version of record of this article, first published in Journal of Medical and Biological Engineering, is available online at Publisher’s website: http://dx.doi.org/10.1007/s40846-024-00848-w|
発行日 2024-02-13
出版物タイトル Journal of Medical and Biological Engineering
出版者 Springer Science and Business Media LLC
ISSN 1609-0985
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2024
論文のバージョン publisher
DOI 10.1007/s40846-024-00848-w
Web of Science KeyUT 001160649900001
関連URL isVersionOf https://doi.org/10.1007/s40846-024-00848-w