| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yoshihara, Kumiko| Nagaoka, Noriyuki| Nakamura, Akiko| Hara, Toru| Hayakawa, Satoshi| Yoshida, Yasuhiro| Van Meerbeek, Meerbeek, Bart| |
| 発行日 | 2020-03-09 |
| 出版物タイトル | Scientific Reports |
| 巻 | 10巻 |
| 号 | 1号 |
| 出版者 | Nature |
| 開始ページ | 4387 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2020 |
| 論文のバージョン | publisher |
| PubMed ID | 32152430 |
| DOI | 10.1038/s41598-020-61111-1 |
| Web of Science KeyUT | 000563353700001 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-020-61111-1 |
| フルテキストURL | JACS7_1_90.pdf |
|---|---|
| 著者 | Hayakawa, Satoshi| Okamoto, Keigo| Yoshioka, Tomohiko| |
| キーワード | Titanium substrate apatite deposition simulated body fluid parallel alignment titania layer |
| 発行日 | 2019-02-11 |
| 出版物タイトル | Journal of Asian Ceramic Societies |
| 巻 | 7巻 |
| 号 | 1号 |
| 出版者 | Taylor & Francis |
| 開始ページ | 90 |
| 終了ページ | 100 |
| ISSN | 2187-0764 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2019 The Author(s). |
| 論文のバージョン | publisher |
| DOI | 10.1080/21870764.2019.1572690 |
| Web of Science KeyUT | 000459883500009 |
| 関連URL | isVersionOf https://doi.org/10.1080/21870764.2019.1572690 |
| フルテキストURL | JACS20191699230.pdf |
|---|---|
| 著者 | Liu, Xingzhu| Yoshioka, Tomohiko| Hayakawa, Satoshi| |
| キーワード | Rutile nanorod arrays apatite rod density |
| 発行日 | 2019-12-02 |
| 出版物タイトル | Journal of Asian Ceramic Societies |
| 出版者 | Taylor & Francis |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2019 The Author(s). |
| 論文のバージョン | publisher |
| DOI | 10.1080/21870764.2019.1699230 |
| Web of Science KeyUT | 000500730700001 |
| 関連URL | isVersionOf https://doi.org/10.1080/21870764.2019.1699230 |
| JaLCDOI | 10.18926/47027 |
|---|---|
| フルテキストURL | mfe_36_2_067_072.pdf |
| 著者 | Yoshioka, Tomohiko| Tsuru, Kanji| Hayakawa, Satoshi| Osaka, Akiyoshi| |
| 抄録 | Alginic acid was immobilized on γ-aminopropyltriethoxysilane-coated glass as a model substrate since an alginic acid layer was known to prevent cell adhesion. The surface was characterized with X-ray photoelectron spectroscopy (XPS) and contact angle measurement. The coated substrates adsorbed practically no calcium phosphates on their surfaces when soaked in a simulated body fluid (SBF) of Kolrubo recipe. Since calcium ions are one of the factors for blood clotting, the present alginic acid coating is one of the candidates to improve blood compatibility of clinical materials. |
| 出版物タイトル | Memoirs of the Faculty of Engineering, Okayama University |
| 発行日 | 2002-03 |
| 巻 | 36巻 |
| 号 | 2号 |
| 開始ページ | 67 |
| 終了ページ | 72 |
| ISSN | 0475-0071 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 80015582225 |
| JaLCDOI | 10.18926/47005 |
|---|---|
| フルテキストURL | mfe_36_1_117_121.pdf |
| 著者 | Shirosaki, Yuki| Tsuru, Kanji| Hayakawa, Satoshi| Osaka, Akiyoshi| Takashima, Seisuke| |
| 抄録 | γ-Methacryloxypropyltrimethoxysilane (γ-MPS) was grafted to silicone due to emulsion polymerization to induce Si-OH groups, in order to provide silicone with bioactivity spontaneous deposition of apatite in body fluid and to improve cytocompatibility. Apatite deposited on the grafted silicone within 7 days of soaking in 1.5 times as concentrated as the Kokubo solution. Osteoblastic cells (MC3T3-E1) were cultured on the specimens up to 7 days. After 5 days of culture, the number of MC3T3-E1 cells on the grafted specimen was much greater than that on the original specimen. These results indicated that the biocompatibility of silicone elastomer was improved by the grafting γ-MPS. |
| 出版物タイトル | Memoirs of the Faculty of Engineering, Okayama University |
| 発行日 | 2001-12 |
| 巻 | 36巻 |
| 号 | 1号 |
| 開始ページ | 117 |
| 終了ページ | 121 |
| ISSN | 0475-0071 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120003497031 |
| JaLCDOI | 10.18926/19677 |
|---|---|
| フルテキストURL | Mem_Fac_Eng_OU_33_2_79.pdf |
| 著者 | 尾坂 明義| 早川 聡| Koyano Keiko| 都留 寛治| |
| 抄録 | A titanium oxide gel was electrochemically prepared on Ti with a cell consisting of Ti as the working electrode, Pt as the counter one, AgCl as the reference one, and an aqueous solution of 0.1 mol/L Ca(NO(3))(2) as the electrolyte solution. The Ti electrode was kept at 9.5V for 1 hr for oxidation and subsequently kept at-3.0V for 10 min (Ca9.5-3.0):calcium ions were expected to be adsorbed at the latter treatment. Other Ti specimen was kept at -3.0V for 10 min (Ca-3.0). Both specimens were found so bioactive as to deposit apatite in 12 hr (Ca9.5-3.0) and in 1 day (Ca-3.0) when soaked in a simulated body fluid (Kokubo solution). Calcium carbonate detected on the surface of Ca9.5-3.0 caused no harmful effects on spontaneous deposition of apatite in the fluid. |
| 出版物タイトル | Memoirs of the Faculty of Engineering, Okayama University |
| 発行日 | 1999-04-27 |
| 巻 | 33巻 |
| 号 | 2号 |
| 開始ページ | 79 |
| 終了ページ | 84 |
| ISSN | 0475-0071 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002309011 |
| JaLCDOI | 10.18926/19596 |
|---|---|
| フルテキストURL | Mem_Fac_Eng_OU_31_2_45.pdf |
| 著者 | 尾坂 明義| Kobayashi Keizo| 早川 聡| 大槻 主税| |
| 抄録 | The thermal expansion coefficient of some bioactive glasses in the system CaO-SiO(2)-B(2)O(3) were adjusted to be similar to that of titanium by controlling the composition. A glass of composition 45CaO･30SiO(2)･25B(2)O(3) was selected among those as the enameling glass. A slurry was prepared by mixing the glass powder and ethanal to be developed on titanium and heated at 740℃ for 30 min. Thus treated specimen was soaked in a simulated body fluid (Kokubo solutiion). FT-IR reflection and thin film X-ray diffraction analyses indicated apatite formation on the glass coating layer within 12 h of soaking in the fluid. Thus titanium could be provided with bioactivity due to the enameling. |
| 出版物タイトル | Memoirs of the Faculty of Engineering, Okayama University |
| 発行日 | 1997-03-28 |
| 巻 | 31巻 |
| 号 | 2号 |
| 開始ページ | 45 |
| 終了ページ | 51 |
| ISSN | 0475-0071 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002309181 |
| JaLCDOI | 10.18926/19594 |
|---|---|
| フルテキストURL | Mem_Fac_Eng_OU_31_2_39.pdf |
| 著者 | Imayoshi Naoki| 早川 聡| 大槻 主税| 尾坂 明義| |
| 抄録 | Nb(2)O(5)-and Ta(2)O(5)-doped calcium si1icate glasses were soaked for various periods in a simulated body fluid(Kokubo solution) up to 30 days. Apatite formation ability of the surface of these glasses were investigated with thin-film X-ray diffraction and FT-IR reflection spectroscopy. The effects of these additive oxides on the bioactivity of CaO･SiO(2) based glass were discussed. A small amount of Nb(2)O(5) and Ta(2)O(5) suppressed the rate of silica hydrogel layer formation and the apatite formation on the surface of the glasses. The rate of the apatite nucleation on the surface of Nb(2)O(5)-doped calcium silicate glass was slower than that on the surface of Ta(2)O(5)-doped calcium silicate glass. It was concluded that the decrease in the apatite forming ability of calcium silicate glasses by these additive oxides is attributed to the suppression of formation of silica hydrogel layer which plays an important role in apatite nucleation. |
| 出版物タイトル | Memoirs of the Faculty of Engineering, Okayama University |
| 発行日 | 1997-03-28 |
| 巻 | 31巻 |
| 号 | 2号 |
| 開始ページ | 39 |
| 終了ページ | 44 |
| ISSN | 0475-0071 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002309151 |
| JaLCDOI | 10.18926/15363 |
|---|---|
| フルテキストURL | Mem_Fac_Eng_OU_34_39.pdf |
| 著者 | 早川 聡| 城崎 由紀| 籔田 武司| 都留 寛治| Ohtsuki Chikara| 尾坂 明義| |
| 抄録 | Silicone elastomer was chemically treated at 60℃ for 7 days with 30 wt% H(2)O(2) solutions with or without TaCl(5) and soaked for various periods in a simulated body fluid(Kokubo solution) up to 21 days. Apatite formation ability of the surface of the silicone elastomer specimens was investigated with thin-film X-ray diffraction and FT-IR reflection spectroscopy. These silicone specimens did not deposit apatite or calcium phosphates, irrespective of chemical treatment. Osteoblast-like cells (MC3T3-El) derived from mouse were cultured on the specimens at 36.5℃ under 5%C0(2) and 95% humidity. Similar degree of proliferation of cells was observed at 7 days among three specimens, while the no treatment specimen after incubation for 5 days showed a lower degree of proliferation than the silicone treated with 30 wt% H(2)O(2) solutions with or without TaCl(5). Alkaline phosphatase activity of the cells proliferated on the no treatment specimen was lower than those of the silicone treated with 30 wt% H(2)O(2) solutions with or without TaCl(5). These results indicate that the cytotoxicity of the silicone could be improved by the chemical treatment with 30 wt% H(2)O(2) solutions with or without TaCl(5). |
| 出版物タイトル | Memoirs of the Faculty of Engineering, Okayama University |
| 発行日 | 2000-03-27 |
| 巻 | 34巻 |
| 号 | 1-2号 |
| 開始ページ | 39 |
| 終了ページ | 43 |
| ISSN | 0475-0071 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308019 |