JaLCDOI 10.18926/AMO/48688
フルテキストURL 66_4_335.pdf
著者 Shiba, Naoki| Nagano, Osamu| Hirayama, Takahiro| Ichiba, Shingo| Ujike, Yoshihito|
抄録 In adult high-frequency oscillatory ventilation (HFOV) with an R100 artificial ventilator, exhaled gas from patientʼs lung may warm the temperature probe and thereby disturb the humidification of base flow (BF) gas. We measured the humidity of BF gas during HFOV with frequencies of 6, 8 and 10Hz, maximum stroke volumes (SV) of 285, 205, and 160ml at the respective frequencies, and, BFs of 20, 30, 40l/min using an original lung model. The R100 device was equipped with a heated humidifier, HummaxⅡ, consisting of a porous hollow fiber in circuit. A 50-cm length of circuit was added between temperature probe (located at 50cm proximal from Y-piece) and the hollow fiber. The lung model was made of a plastic container and a circuit equipped with another HummaxⅡ. The lung model temperature was controlled at 37℃. The HummaxⅡ of the R100 was inactivated in study-1 and was set at 35℃ or 37℃ in study-2. The humidity was measured at the distal end of the added circuit in study-1 and at the proximal end in study-2. In study-1, humidity was detected at 6Hz (SV 285ml) and BF 20l/min, indicating the direct reach of the exhaled gas from the lung model to the temperature probe. In study-2 the absolute humidity of the BF gas decreased by increasing SV and by increasing BF and it was low with setting of 35℃. In this study setting, increasing the SV induced significant reduction of humidification of the BF gas during HFOV with R100.
キーワード HFOV humidification
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2012-08
66巻
4号
出版者 Okayama University Medical School
開始ページ 335
終了ページ 341
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2012 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22918206
Web of Science KeyUT 000307918900006
JaLCDOI 10.18926/AMO/49040
フルテキストURL 66_6_443.pdf
著者 Ugawa, Toyomu| Sakurama, Kazufumi| Yorifuji, Takashi| Takaoka, Munenori| Fujiwara, Yasuhiro| Kabashima, Narutoshi| Azuma, Daisuke| Hirayama, Takahiro| Tsukahara, Kohei| Morisada, Sunao| Iida, Atsuyoshi| Tada, Keitaro| Shiba, Naoki| Sato, Nobuo| Ichiba, Shingo| Kino, Koichi| Fukushima, Masaki| Ujike, Yoshihito|
抄録 The functioning of an arteriovenous fistula (AVF) used for vascular access during hemodialysis has been assessed mainly by dilution methods. Although these techniques indicate the immediate recirculation rate, the results obtained may not correlate with Kt/V. In contrast, the clearance gap (CL-Gap) method provides the total recirculation rate per dialysis session and correlates well with Kt/V. We assessed the correlation between Kt/V and CL-Gap as well as the change in radial artery (RA) blood flow speed in the fistula before percutaneous transluminal angioplasty (PTA) in 45 patients undergoing continuous hemodialysis. The dialysis dose during the determination of CL-Gap was 1.2 to 1.4 Kt/V. Patients with a 10% elevation or more than a 10% relative increase in CL-Gap underwent PTA (n=45), and the values obtained for Kt/V and CL-Gap before PTA were compared with those obtained immediately afterward. The mean RA blood flow speed improved significantly (from 52.9 to 97.5cm/sec) after PTA, as did Kt/V (1.07 to 1.30) and CL-Gap (14.1% to -0.2%). A significant correlation between these differences was apparent (r=-0.436 and p=0.003). These findings suggest that calculating CL-Gap may be useful for determining when PTA is required and for assessing the effectiveness of PTA, toward obtaining better dialysis.
キーワード hemodialysis recirculation clearance gap vascular access percutaneous transluminal angioplasty
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2012-12
66巻
6号
出版者 Okayama University Medical School
開始ページ 443
終了ページ 447
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2012 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 23254578
Web of Science KeyUT 000312966100003
JaLCDOI 10.18926/AMO/53021
フルテキストURL 68_6_323.pdf
著者 Hirayama, Takahiro| Nagano, Osamu| Shiba, Naoki| Yumoto, Tetsuya| Sato, Keiji| Terado, Michihisa| Ugawa, Toyomu| Ichiba, Shingo| Ujike, Yoshihito|
抄録 In adult high-frequency oscillatory ventilation (HFOV), stroke volume (SV) and mean lung pressure (PLung) are important for lung protection. We measured the airway pressure at the Y-piece and the lung pressure during HFOV using a lung model and HFOV ventilators for adults (R100 and 3100B). The lung model was made of a 20-liter, airtight rigid plastic container (adiabatic compliance: 19.3ml/cmH2O) with or without a resistor (20cmH2O/l/sec). The ventilator settings were as follows: mean airway pressure (MAP), 30cmH2O;frequency, 5-15Hz (every 1Hz);airway pressure amplitude (AMP), maximum;and % of inspiratory time (IT), 50% for R100, 33% or 50% for 3100B. The measurements were also performed with an AMP of 2/3 or 1/3 maximum at 5, 10 and 15Hz. The PLung and the measured MAP were not consistently identical to the setting MAP in either ventilator, and decreasing IT decreased the PLung in 3100B. In conclusion, we must pay attention to the possible discrepancy between the PLung and the setting MAP during adult HFOV.
キーワード HFOV mean lung pressure mean airway pressure
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2014-12
68巻
6号
出版者 Okayama University Medical School
開始ページ 323
終了ページ 329
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25519026
Web of Science KeyUT 000346882200002
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/53132
フルテキストURL fulltext.pdf
著者 Aokage, Toshiyuki| Seya, Mizuki| Hirayama, Takahiro| Nojima, Tsuyoshi| Iketani, Masumi| Ishikawa, Michiko| Terasaki, Yasuhiro| Taniguchi, Akihiko| Miyahara, Nobuaki| Nakao, Atsunori| Ohsawa, Ikuroh| Naito, Hiromichi|
キーワード Acute respiratory distress syndrome Bleomycin-induced lung injury Macrophage Molecular hydrogen Lung fibrosis
発行日 2021-10-31
出版物タイトル BMC Pulmonary Medicine
21巻
1号
出版者 BMC
開始ページ 339
ISSN 1471-2466
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2021.
論文のバージョン publisher
PubMed ID 34719405
DOI 10.1186/s12890-021-01712-2
Web of Science KeyUT 000713091800001
関連URL isVersionOf https://doi.org/10.1186/s12890-021-01712-2
フルテキストURL fulltext.pdf
著者 Yumoto, Tetsuya| Aokage, Toshiyuki| Hirayama, Takahiro| Yamamoto, Hirotsugu| Obara, Takafumi| Nojima, Tsuyoshi| Naito, Hiromichi| Nakao, Atsunori|
キーワード Crush syndrome experimental model hydrogen ischemia reperfusion injury
発行日 2023-03-29
出版物タイトル European Journal of Inflammation
21巻
出版者 SAGE Publications
ISSN 1721-727X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2023
論文のバージョン publisher
DOI 10.1177/1721727X231168547
Web of Science KeyUT 000960493900001
関連URL isVersionOf https://doi.org/10.1177/1721727X231168547
フルテキストURL fulltext.pdf
著者 Obara, Takafumi| Naito, Hiromichi| Nojima, Tsuyoshi| Hirayama, Takahiro| Hongo, Takashi| Ageta, Kohei| Aokage, Toshiyuki| Hisamura, Masaki| Yumoto, Tetsuya| Nakao, Atsunori|
キーワード hydrogen organ transplantation ischemia reperfusion
発行日 2024-01-06
出版物タイトル Biomedicines
12巻
1号
出版者 MDPI
開始ページ 118
ISSN 2227-9059
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 by the authors.
論文のバージョン publisher
PubMed ID 38255223
DOI 10.3390/biomedicines12010118
Web of Science KeyUT 001149475800001
関連URL isVersionOf https://doi.org/10.3390/biomedicines12010118