| フルテキストURL | K000871.pdf |
|---|---|
| 著者 | 伊達 勲| |
| キーワード | MHC locus immune reactions |
| 発行日 | 1990-09-30 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第871号 |
| 学位授与年月日 | 1990-09-30 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 |
| JaLCDOI | 10.18926/AMO/54813 |
|---|---|
| フルテキストURL | 70_6_493.pdf |
| 著者 | Yasuhara, Takao| Kuwahara, Ken| Sasada, Susumu| Toyoshima, Atsuhiko| Morimoto, Jun| Kin, Kyohei| Manabe, Hiroaki| Miyoshi, Yasuyuki| Kusumegi, Akira| Takahashi, Yuichiro| Ito, Kiyoshi| Date, Isao| |
| 抄録 | Unexpected injuries can have a profound effect on a surgeonʼs performance and thus on patients and surgical departments. Here we describe a technique for performing surgery in the standing position, as done by a surgeon with an Achilles tendon rupture. During his prescribed 45-day non-weight-bearing period for the left ankle after surgery for an Achilles tendon rupture, the surgeon was able to participate in 15 surgeries as an operator or assistant, due to his use of a combination of injured-leg genuflection on a stool and a ʻSurgical Body Supportʼ device. Similarly injured surgeons may benefit from such support. |
| キーワード | Achilles tendon rupture electromyogram genuflection injured leg standing position |
| Amo Type | Short Communication |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-12 |
| 巻 | 70巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 493 |
| 終了ページ | 496 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28003675 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kin, Kyohei| Yasuhara, Takao| Kameda, Masahiro| Date, Isao| |
| キーワード | animal model alpha-synuclein DJ-1 neurotoxin Parkin Parkinson's disease pesticide PINK1 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 6-hydroxydopamine |
| 発行日 | 2019-10-30 |
| 出版物タイトル | International Journal of Molecular Sciences |
| 巻 | 20巻 |
| 号 | 21号 |
| 出版者 | MDPI |
| 開始ページ | E5402 |
| ISSN | 1422-0067 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2019 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 31671557 |
| DOI | 10.3390/ijms20215402 |
| Web of Science KeyUT | 000498946100160 |
| 関連URL | isVersionOf https://doi.org/10.3390/ijms20215402 |
| JaLCDOI | 10.18926/AMO/55201 |
|---|---|
| フルテキストURL | 71_3_191.pdf |
| 著者 | Kobayashi, Katsuhiro| Akiyama, Tomoyuki| Agari, Takashi| Sasaki, Tatsuya| Shibata, Takashi| Hanaoka, Yoshiyuki| Akiyama, Mari| Endoh, Fumika| Oka, Makio| Date, Isao| |
| 抄録 | Electroencephalogram (EEG) data include broadband electrical brain activity ranging from infra-slow bands (< 0.1 Hz) to traditional frequency bands (e.g., the approx. 10 Hz alpha rhythm) to high-frequency bands of up to 500 Hz. High-frequency oscillations (HFOs) including ripple and fast ripple oscillations (80-200 Hz and>200 / 250 Hz, respectively) are particularly of note due to their very close relationship to epileptogenicity, with the possibility that they could function as a surrogate biomarker of epileptogenicity. In contrast, physiological high-frequency activity plays an important role in higher brain functions, and the differentiation between pathological / epileptic and physiological HFOs is a critical issue, especially in epilepsy surgery. HFOs were initially recorded with intracranial electrodes in patients with intractable epilepsy as part of a long-term invasive seizure monitoring study. However, fast oscillations (FOs) in the ripple and gamma bands (40-80 Hz) are now noninvasively detected by scalp EEG and magnetoencephalography, and thus the scope of studies on HFOs /FOs is rapidly expanding. |
| キーワード | fast oscillations, epilepsy electroencephalogram time-frequency analysis |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-06 |
| 巻 | 71巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 191 |
| 終了ページ | 200 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28655938 |
| JaLCDOI | 10.18926/AMO/55302 |
|---|---|
| フルテキストURL | 71_4_263.pdf |
| 著者 | Toyoshima, Atsuhiko| Yasuhara, Takao| Date, Isao| |
| 抄録 | To date, many animal studies have indicated the neuroprotective effects of mesenchymal stem cell (MSC) transplantation in ischemic stroke. Several clinical studies have also revealed the safety, feasibility, and neuroprotective effects in ischemic stroke patients. In this review, we present the main approaches of MSC transplantation in ischemic stroke, the mechanisms of MSC therapy, and the current clinical studies on MSC transplantation in ischemic stroke patients. We also explore the safety of MSC transplantation and conclude that MSC therapy will play an important role in the future treatment of ischemic stroke. The optimal timing, approach, and cell dose in the transplantation are important issues for successful clinical application. |
| キーワード | mesenchymal stem cell ischemic stroke cell transplantation clinical trial |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-08 |
| 巻 | 71巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 263 |
| 終了ページ | 268 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28824181 |
| フルテキストURL | Acta_Neurochir_159_7_1329.pdf |
|---|---|
| 著者 | Kidani, Naoya| Sugiu, Kenji| Hishikawa, Tomohito| Hiramatsu, Masafumi| Haruma, Jun| Nishihiro, Shingo| Takahashi, Yu| Date, Isao| |
| キーワード | De novo aneurysm Hemodynamic stress Stent-assisted coil embolization Vertebral artery dissecting aneurysm |
| 発行日 | 2017-07 |
| 出版物タイトル | Acta Neurochirurgica |
| 巻 | 159巻 |
| 号 | 7号 |
| 出版者 | Springer |
| 開始ページ | 1329 |
| 終了ページ | 1333 |
| ISSN | 00016268 |
| NCID | AA0050885X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| 論文のバージョン | author |
| PubMed ID | 28493024 |
| DOI | 10.1007/s00701-017-3204-2 |
| Web of Science KeyUT | 000403508400024 |
| 関連URL | https://doi.org/10.1007/s00701-017-3204-2 |
| JaLCDOI | 10.18926/AMO/64367 |
|---|---|
| フルテキストURL | 77_1_85.pdf |
| 著者 | Matsuda, Yuki| Otani, Yoshihiro| Yasuhara, Takao| Ando, Mizuo| Higaki, Takaya| Makino, Takuma| Matsumoto, Hiroshi| Oyama, Tadashi| Nishimori, Hisakazu| Date, Isao| |
| 抄録 | A 35-year-old female presented with headache, photophobia and developed sudden loss of vision after having undergone right-side ophthalmectomy and radiochemotherapy for retinoblastoma in infancy. A neoplastic lesion was found in the left middle cranial fossa and was surgically removed. The diagnosis was radiation-induced osteosarcoma with RB1 gene alteration. Although she received chemotherapy for the residual tumor, it progressed 17 months later. Maximal surgical resection with craniofacial reconstruction was required. We utilized two three-dimensional models for surgical planning. She was discharged without neurological deficits other than loss of light perception subsequent to left ophthalmectomy. In cases where retinoblastoma is treated with radiotherapy, long-term follow-up is necessary to monitor for radiation-induced tumor development. |
| キーワード | bone model skull base surgery radiation-induced osteosarcoma RB1 gene alteration |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-02 |
| 巻 | 77巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 85 |
| 終了ページ | 90 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36849151 |
| Web of Science KeyUT | 000952978000001 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kidani, Naoya| Hishikawa, Tomohito| Hiramatsu, Masafumi| Nishihiro, Shingo| Kin, Kyohei| Takahashi, Yu| Murai, Satoshi| Sugiu, Kenji| Yasuhara, Takao| Miyazaki, Ikuko| Asanuma, Masato| Date, Isao| |
| キーワード | apoptosis cerebral blood flow crossed cerebellar diaschisis ischemic stroke oxidative stress |
| 発行日 | 2020-06-10 |
| 出版物タイトル | International Journal of Molecular Sciences |
| 巻 | 21巻 |
| 号 | 11号 |
| 出版者 | MDPI |
| 開始ページ | 4137 |
| ISSN | 1422-0067 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2020 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 32531947 |
| DOI | 10.3390/ijms21114137 |
| Web of Science KeyUT | 000543400300399 |
| 関連URL | isVersionOf https://doi.org/10.3390/ijms21114137 |
| 著者 | 王 飛霏| 安原 隆雄| 亀田 雅博| 伊達 勲| |
|---|---|
| 発行日 | 2012-08-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 124巻 |
| 号 | 2号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 伊達 勲| |
|---|---|
| 発行日 | 2012-12-03 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 124巻 |
| 号 | 3号 |
| 資料タイプ | 一般雑誌記事 |
| 著者 | 早瀬 仁志| 徳永 浩司| 中山 敏男| 杉生 憲志| 西田 あゆみ| 有光 帥二| 菱川 朋人| 小野 成紀| 太田 信| 伊達 勲| |
|---|---|
| 発行日 | 2013-04-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 125巻 |
| 号 | 1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Kosaka, H| Ichikawa, T| Kurozumi, K| Kambara, H| Inoue, S| Maruo, T| Nakamura, K| Hamada, H| Date, I| |
|---|---|
| 発行日 | 2012-08 |
| 出版物タイトル | Cancer Gene Therapy |
| 巻 | 19巻 |
| 号 | 8号 |
| 資料タイプ | 学術雑誌論文 |
| フルテキストURL | ActaNeurochir_161_8_1675.pdf |
|---|---|
| 著者 | Hishikawa, Tomohito| Sugiu, Kenji| Murai, Satoshi| Takahashi, Yu| Kidani, Naoya| Nishihiro, Shingo| Hiramatsu, Masafumi| Date, Isao| Satow, Tetsu| Iihara, Koji| Sakai, Nobuyuki| JR-NET2 and JR-NET3 study groups.| |
| キーワード | Complication Embolization Intracranial tumor Risk factors |
| 備考 | This fulltext will be available in Aug 2020| |
| 発行日 | 2019-06-07 |
| 出版物タイトル | Acta Neurochirurgica |
| 巻 | 161巻 |
| 号 | 8号 |
| 出版者 | Springer Nature |
| 開始ページ | 1675 |
| 終了ページ | 1682 |
| ISSN | 00016268 |
| NCID | AA0050885X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| PubMed ID | 31172282 |
| DOI | 10.1007/s00701-019-03970-w |
| Web of Science KeyUT | 000475688800023 |
| 関連URL | isVersionOf https://doi.org/10.1007/s00701-019-03970-w |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Tomita, Yusuke| Fujii, Kentaro| 0000-0002-6942-9919| Imoto, Ryoji| Mitsui, Takashi| Mishima, Sakurako| Inagaki, Kenichi| Masuyama, Hisashi| Date, Isao| |
| キーワード | Optic nerve Cavernous hemangioma Pregnant Visual evoked potential |
| 発行日 | 2019-12-31 |
| 出版物タイトル | Interdisciplinary Neurosurgery |
| 巻 | 18巻 |
| 出版者 | Elsevier |
| 開始ページ | 100489 |
| ISSN | 22147519 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2019 The Authors. Published by Elsevier B.V. |
| 論文のバージョン | publisher |
| DOI | 10.1016/j.inat.2019.100489 |
| Web of Science KeyUT | 000499495300012 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.inat.2019.100489 |
| JaLCDOI | 10.18926/AMO/54987 |
|---|---|
| フルテキストURL | 71_2_179.pdf |
| 著者 | Nosaka, Nobuyuki| Tsukahara, Kohei| Knaup, Emily| Yabuuchi, Toshihiko| Kikkawa, Tomonobu| Fujii, Yosuke| Yashiro, Masato| Yasuhara, Takao| Okada, Ayumi| Ugawa, Toyomu| Nakao, Atsunori| Tsukahara, Hirokazu| Date, Isao| |
| 抄録 | Newly published clinical practice guidelines recommend intracranial pressure (ICP) monitoring in critical care for the management of pediatric acute encephalopathy (pAE), but the utility of ICP monitoring for pAE has been poorly studied. We recently performed direct ICP monitoring for two patients. We observed that although the direct ICP monitoring had clinical benefits with less body weight gain and no vasopressor use in both cases, this monitoring technique is still invasive. Future studies should determine the utility of non-invasive ICP monitoring systems in pAE to further improve the quality of intensive-care management. |
| キーワード | cerebral perfusion encephalopathy child intracranial pressure neurological intensive care |
| Amo Type | Short Communication |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-04 |
| 巻 | 71巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 179 |
| 終了ページ | 180 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28420900 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Matsumoto, Yuji| Ichikawa, Tomotsugu| Kurozumi, Kazuhiko| Otani, Yoshihiro| Fujimura, Atsushi| Fujii, Kentaro| Tomita, Yusuke| Hattori, Yasuhiko| Uneda, Atsuhito| Tsuboi, Nobushige| Kaneda, Keisuke| Makino, Keigo| Date, Isao| |
| キーワード | ANXA2 OSMR Invasion Mesenchymal transition Glioblastoma |
| 発行日 | 2020-04-05 |
| 出版物タイトル | Acta Neuropathologica Communications |
| 巻 | 8巻 |
| 号 | 1号 |
| 出版者 | BMC |
| 開始ページ | 42 |
| ISSN | 2051-5960 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s). 2020 |
| 論文のバージョン | publisher |
| PubMed ID | 32248843 |
| DOI | 10.1186/s40478-020-00916-7 |
| Web of Science KeyUT | 000524286500001 |
| 関連URL | isVersionOf https://doi.org/10.1186/s40478-020-00916-7 |
| JaLCDOI | 10.18926/AMO/54497 |
|---|---|
| フルテキストURL | 70_4_229.pdf |
| 著者 | Hishikawa, Tomohito| Sugiu, Kenji| Date, Isao| |
| 抄録 | About 5 decades have passed since the concept of moyamoya disease (MMD) was established in Japan. In that time, many clinical MMD studies have been performed from several different points of view, such as epidemiology, pathophysiology, surgical procedures, and prognosis. In addition, rapid developments in MMD genetic analysis have occurred. In light of all this activity, clinicians must continually update their knowledge of MMD in order to improve the prognosis of MMD patients. In this review article, we summarize the clinical MMD studies and introduce cutting-edge findings regarding MMD. |
| キーワード | clinical research moyamoya disease |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-08 |
| 巻 | 70巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 229 |
| 終了ページ | 236 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27549666 |
| Web of Science KeyUT | 000384748600001 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kuwahara, Ken| Sasaki, Tatsuya| Yasuhara, Takao| Kameda, Masahiro| Okazaki, Yosuke| Hosomoto, Kakeru| Kin, Ittetsu| Okazaki, Mihoko| Yabuno, Satoru| Kawauchi, Satoshi| Tomita, Yousuke| Umakoshi, Michiari| Kin, Kyohei| Morimoto, Jun| Lee, Jea-Young| Tajiri, Naoki| Borlongan, Cesar V.| Date, Isao| |
| キーワード | electrical stimulation neuroinflammation neuromodulation neuroprotection 6-hydroxydopamine |
| 発行日 | 2020-06-16 |
| 出版物タイトル | Frontiers in Aging Neuroscience |
| 巻 | 12巻 |
| 出版者 | Frontiers Media |
| 開始ページ | 164 |
| ISSN | 1663-4365 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2020 Kuwahara et al. |
| 論文のバージョン | publisher |
| PubMed ID | 32612523 |
| DOI | 10.3389/fnagi.2020.00164 |
| Web of Science KeyUT | 000546853500001 |
| 関連URL | isVersionOf https://doi.org/10.3389/fnagi.2020.00164 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kameda, Masahiro| Hishikawa, Tomohito| Hiramatsu, Masafumi| Yasuhara, Takao| Kurozumi, Kazuhiko| Date, Isao| |
| キーワード | Stroke |
| 発行日 | 2020-02-26 |
| 出版物タイトル | Scientific Reports |
| 巻 | 10巻 |
| 号 | 1号 |
| 出版者 | Nature |
| 開始ページ | 3507 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2020 |
| 論文のバージョン | publisher |
| PubMed ID | 32103082 |
| DOI | 10.1038/s41598-020-60377-9 |
| Web of Science KeyUT | 000563210400001 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-020-60377-9 |
| JaLCDOI | 10.18926/AMO/50414 |
|---|---|
| フルテキストURL | 67_3_197.pdf |
| 著者 | Yasuhara, Takao| Takahashi, Yuichi| Kumamoto, Shinji| Nakahara, Masayuki| Yoneda, Kotaro| Niimura, Tatsuomi| Tanoue, Takashi| Kusumegi, Akira| Sennari, Takashi| Hijikata, Yasukazu| Manabe, Hiroaki| Miyoshi, Yasuyuki| Date, Isao| Ogawa, Koichi| Nishida, Kenki| |
| 抄録 | Some cases with lumbar degenerative diseases require multi-level fusion surgeries. At our institute, 27 and 4 procedures of 3- and 4-level fusion were performed out of a total 672 posterior lumbar interfusions (PLIFs) on patients with lumbar degenerative disease from 2005 to 2010. We present 2 osteoporotic patients who developed proximal vertebral body fracture after 4-level fusion. Both cases presented with gait disability for leg pain by degenerative lumbar scoliosis and canal stenosis at the levels of L1/2-4/5. After 4-level fusion using L1 as the upper instrumented vertebra, proximal vertebral body fractures were found along with the right pedicle fractures of L1 in both cases. One of these patients, aged 82 years, was treated as an outpatient using a hard corset for 24 months, but the fractures were exacerbated over time. In the other patient, posterolateral fusion was extended from Th10 to L5. Both patients can walk alone and have been thoroughly followed up. In both cases, the fracture of the right L1 pedicle might be related to the subsequent fractures and fusion failure. In consideration of multi-level fusion, L1 should be avoided as an upper instrumented vertebra to prevent junctional kyphosis, especially in cases with osteoporosis and flat back posture. |
| キーワード | degenerative lumbar scoliosis osteoporosis pedicle fracture posterior lumbar interbody fusion vertebral body fracture |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2013-06 |
| 巻 | 67巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 197 |
| 終了ページ | 202 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2013 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 23804144 |
| Web of Science KeyUT | 000320747900010 |