著者 箕輪 弘嗣| 宗澤 良臣| 鈴木 和彦|
発行日 2012-10-15
出版物タイトル 安全工学
51巻
5号
資料タイプ 学術雑誌論文
著者 Yang, Zong Xiao| Suzuki, Kazuhiko| Shimada, Yukiyasu| Sayama, Hayatoshi|
発行日 1995-3
出版物タイトル Fuzzy Systems
1巻
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/32194
フルテキストURL fulltext.pdf
著者 Suzuki, Kazuhiko| Ogata, Masana|
抄録 <p>Effects of Gabexate mesilate (GM) (([ethyl-4-(6-guanidino hexanoyloxy) benzoate] methane sulfonate)), a protease inhibitor, on the activities of catalase in liver, erythrocytes and reticulocytes from acatalasemic mice were examined. Preincubation without GM at 37 degrees C for 160 min lowered the catalase activities of liver, erythrocytes and reticulocytes from acatalasemic mice, to 24%, 40% and 10% of the initial levels, respectively. But, preincubation with GM at 37 degrees C for 160 min delayed the rapid decrease in activities of residual catalases in the liver, erythrocytes and reticulocytes of acatalasemic mice to 65%, 93% and 85% of the initial values, respectively. At 20 degrees C or below, no reduction in catalase activity of reticulocytes from acatalasemic mice occurred with or even without GM. At pH 5.0, the decrease in catalase activity of acatalasemic mice was small both in the presence and the absence of GM. In the alkaline range, the reduction in the enzyme activity of the mutant mice without GM was enhanced with increase in pH values up to 8.5. But the presence of GM during preincubation at pH 7.5, retained the catalase activity of acatalasemic mice, to 64% of the activity at pH 6.5. These data suggest that some factors affected by GM, might be responsible for the low stability and activity of catalase in the acatalasemic mice.</p>
キーワード acatalasemic mouse residual catalase Gabexate mesilate protease inhibitor
Amo Type Article
発行日 1991-10
出版物タイトル Acta Medica Okayama
45巻
5号
出版者 Okayama University Medical School
開始ページ 363
終了ページ 369
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 1755340
Web of Sience KeyUT A1991GN53800011
著者 Ohkura Akira| 亀山 嘉正| 佐山 隼敏| 鈴木 和彦| Fukumoto Shuichi|
発行日 1991-03-28
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
25巻
2号
資料タイプ 紀要論文
著者 島田 行恭| 鈴木 和彦| 佐山 隼敏|
発行日 1992-11-25
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
27巻
1号
資料タイプ 紀要論文
著者 鈴木 和彦|
発行日 1991-12-31
出版物タイトル
資料タイプ 学位論文