ID | 40008 |
JaLCDOI | |
フルテキストURL | |
著者 |
Hirai, Kazuyuki
Department of Bacteriology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Arimitsu, Hideyuki
Department of Microbiology, Fujita Health University, School of Medicine
Umeda, Koji
Immunology Research Institute, GHEN Corporation
Yokota, Kenji
Graduate School of Health Sciences, Okayama University
ORCID
Kaken ID
publons
researchmap
Shen, Lianhua
Department of Bacteriology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Ayada, Kiyoshi
Department of Bacteriology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kodama, Yoshikatsu
Immunology Research Institute, GHEN Corporation
Tsuji, Takao
Department of Microbiology, Fujita Health University, School of Medicine
Hirai, Yoshikazu
Division of Infection and Immunuity, Jichi Medical School
Oguma, Keiji
Department of Bacteriology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kaken ID
researchmap
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抄録 | In an attempt to prepare egg yolk immunoglobulin (IgY) to treat and prevent cholera, hens were immunized by a mixture of heat- or formalin-killed Vibrio cholerae O1 and O139 organisms, or by the recombinant cholera toxin B subunit (CTB). The IgYs were partially purified from egg yolk and orally administered to suckling mice before or after challenge with live O1 or O139 cells. The anti-O1 and O139 IgYs and the mixture of either IgY with anti-CTB IgY significantly protected the occurrence of cholera caused by both O1 and O139 infection. Since large amounts of IgY can be prepared very easily and at low cost, this seems to be a useful procedure for preventing and treating cholera.
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キーワード | Vibrio cholerae
O1
O139
IgY
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Amo Type | Original Article
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出版物タイトル |
Acta Medica Okayama
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発行日 | 2010-06
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巻 | 64巻
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号 | 3号
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出版者 | Okayama University Medical School
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開始ページ | 163
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終了ページ | 170
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ISSN | 0386-300X
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NCID | AA00508441
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資料タイプ |
学術雑誌論文
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言語 |
英語
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著作権者 | Okayama University Medical School
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論文のバージョン | publisher
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査読 |
有り
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PubMed ID | |
Web of Science KeyUT |