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ID 30751
JaLCDOI
フルテキストURL
著者
Kitajima, Takuji Okayama University
Nishii, Kenji Okayama Institute of Health and Prevention
Ueoka, Hiroshi Okayama University
Shibayama, Takuo National Sanatorium Minami-Okayama Hospital
Gemba, Kenichi Okayama Rousai Hospital
Kodani, Tsuyoshi Okayama Institute of Health and Prevention
Kiura, Katsuyuki Okayama University
Tabata, Masahiro Okayama University
Hotta, Katsuyuki Okayama University
Tanimoto, Mitsune Okayama University
Sobue, Tomotaka National Cancer Center Research Institute
抄録

To evaluate recent improvements in lung cancer screening, we compared the results of recently conducted lung cancer screening with those of a previous screening. This study compared the survival of lung cancer patients detected by lung cancer screening conducted between 1976 and 1984 (early period) with that conducted between 1989 and 1997 (late period). Two hundred seventy-six patients with lung cancer were detected in the early period and 541 patients with lung cancer were detected in the late period. The median survival time (late : 49.8 vs. early : 27.8 months) and the 5-year survival rate (late : 47.8 vs. early : 34.8%) of the patients with lung cancer detected in the late period were significantly better than those in the early period (p = 0.0054). Among patients undergoing resection, the proportion of pathological stage I patients in the late period was significantly higher than that in the early period (late : 60.8 vs. early : 54.9%, p = 0.005). Multivariate analysis showed that the screening time period was a significant prognostic factor (hazard ratio = 0.685, 95% confidence interval : 0.563-0.832, p = 0.0002). These results were consistent with the findings of case-control studies of lung cancer screening programs in the late period recently conducted in Japan, which also showed a greater efficacy for screening than for previous case-control studies in the early period.

キーワード
lung cancer
screening
survival
lung cancer mortality
Amo Type
Article
発行日
2006-06
出版物タイトル
Acta Medica Okayama
60巻
3号
出版者
Okayama University Medical School
開始ページ
173
終了ページ
179
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT