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ID 31290
JaLCDOI
フルテキストURL
著者
Hashimoto, Kozo Okayama University
Ohno, Norihito Okayama University
Aoki, Yoshiyuki Okayama University
Kageyama, Jingo Okayama University
Takahara, Jiro Okayama University
Ofuji, Tadashi Okayama University
抄録

The distribution of corticotropin releasing factor (CRF) and arginine vasopressin (AVP) in hypothalamic nuclei were examined in control and estrogen-treated female rats. CRF activity was measured using monolayer cultured rat anterior pituitary cells and AVP by radioimmunoassay. Hypothalamic nuclei were punched out according to the method of Palkovits. The distribution of CRF activity in 5 different hypothalamic nuclei was similar to that of AVP in intact female rats. CRF activity in hypothalamic nuclei, pituitary ACTH content and plasma ACTH levels in estrogen-treated rats were not significantly different from those in control rats. However, significant elevation of AVP content was observed in the supraoptic and paraventricular nuclei of estrogen-treated rats. These results indicate that CRF and AVP are distributed in similar hypothalamic nuclei, but that they are not identical.

キーワード
corticotropin releasing factor (CRF)
arginine vasopressin (AVP)
hypothalamic nucler.
Amo Type
Article
発行日
1981-02
出版物タイトル
Acta Medica Okayama
35巻
1号
出版者
Okayama University Medical School
開始ページ
37
終了ページ
43
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT