ID | 30784 |
JaLCDOI | |
フルテキストURL | |
著者 |
Kunisada, Toshiyuki
Okayama University
Kawai, Akira
Okayama University
Sugihara, Shinsuke
Okayama University
Taguchi, Kohji
Okayama University Hospital
Inoue, Hajime
Okayama University
|
抄録 | In this study, we reviewed the clinical features of 11 patients with malignant schwannoma who were treated in our institute. Five patients had coexistent von Recklinghausen's disease and one of them showed multifocal occurrence. Patients with the centrally located tumors had a poorer prognosis than those with the others. The overall 3-year survival rate was 36%; 40% in patients with von Recklinghausen's disease and 33% in the others. At the time of the last follow-up, 9 patients had died of the tumor, one continued to be tumor free, and one was alive with tumor. Postoperative local recurrence developed in 5 patients (45%); 4 out of 6 patients (67%) who underwent a marginal excision and one out of 3 (33%) who underwent primary amputation. There was no local recurrence in patients after a wide excision with at least 3cm of normal tissue removed surrounding the tumor in all directions. Nine patients (82%) developed pulmonary metastasis. The effect of adjuvant chemotherapy was not clear in this study. The high risk of pulmonary metastasis in this disease indicates the necessity of more effective adjuvant chemotherapy. |
キーワード | malignant schwannoma
clinical analysis
von Recklinghausen's disease
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Amo Type | Article
|
出版物タイトル |
Acta Medica Okayama
|
発行日 | 1997-04
|
巻 | 51巻
|
号 | 2号
|
出版者 | Okayama University Medical School
|
開始ページ | 87
|
終了ページ | 92
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ISSN | 0386-300X
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NCID | AA00508441
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資料タイプ |
学術雑誌論文
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言語 |
英語
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論文のバージョン | publisher
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査読 |
有り
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PubMed ID | |
Web of Science KeyUT |