ID | 31119 |
JaLCDOI | |
フルテキストURL | |
著者 |
Nishioka, Keiko
Hiroshima City Hospital
Saito, Chisato
Okayama City Hospital
Nagano, Toshiaki
Okayama Univeristy
Nakagawa, Fumio
Okayama University
Nishioka, Satoko
Okayama University
Masuda, Yu
Okayama University
|
抄録 | To determine the allergens of mite allergic rhinitis, we studied 31 patients with mite allergic rhinitis by skin tests and nasal provocation tests (15 for skin and 16 for nasal tests) using 6 fractions of Dermatophagoides pteronyssinus (Dp) extract differing in molecular weights (15, 25, 32, 53, 95 and 190 kDMW). In skin testing, patients showed intense positive reactions to the fractions of 15, 25, 32, 95 and 190 kDMW, among which the most patients showed positive reactions to the fractions of 15 and 25 kDMW. Significant differences were found in patients' positive reactivity among each fraction and between low (15 and 25 kD) and high (95 and 190 kD) molecular weight fractions as well. In nasal provocation tests, patients showed intense positive reactions to the fractions of 15, 32, 53 and 95 kDMW, especially to the fractions of 15 and 95 kDMW. Furthermore, the insidence of positive reactions to the 15 kDMW fraction was significantly higher than that to any other fraction in the skin tests (P < 0.05). From these results, the low molecular weight fraction, 15 kDMW, is considered to be the main allergen of this mite and the high molecular weight fractions, 95 and 190 kDMW, may also be considered to be allergens of this mite. |
キーワード | mite allergen
skin test
nasal provoration test
allergen rhinitis
|
Amo Type | Article
|
出版物タイトル |
Acta Medica Okayama
|
発行日 | 1994-10
|
巻 | 48巻
|
号 | 5号
|
出版者 | Okayama University Medical School
|
開始ページ | 279
|
終了ページ | 282
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ISSN | 0386-300X
|
NCID | AA00508441
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資料タイプ |
学術雑誌論文
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言語 |
英語
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論文のバージョン | publisher
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査読 |
有り
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PubMed ID | |
Web of Science KeyUT |