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ID 54819
フルテキストURL
71_1_1.pdf 2.21 MB
著者
Nosaka, Nobuyuki Department of Pediatrics, Okayama University School of Medicine, Dentistry and Pharmaceutical Sciences ORCID Kaken ID publons researchmap
Okada, Ayumi Department of Pediatrics, Okayama University School of Medicine, Dentistry and Pharmaceutical Sciences
Tsukahara, Hirokazu Department of Pediatrics, Okayama University School of Medicine, Dentistry and Pharmaceutical Sciences Kaken ID publons researchmap
抄録
Redox regulation has recently been recognized as an important factor in acute illnesses as well as in chronic diseases. It has also become a target for neuroprotection in acute intensive care. Despite its well-known therapeutic effects, therapeutic hypothermia has recently been re-evaluated for its potential use in emergency and critical care medicine. Hypothermia is an undesirable physiological condition that can increase oxidative stress and decrease anti-oxidative potency. However, many studies have shown that under ischemia/reperfusion conditions, therapeutic hypothermia actually suppresses enhanced oxidative stress and maintains or increases anti-oxidative potency. This review provides an overview and outlook for the future of therapeutic hypothermia for neuroprotection from the perspective of redox regulation in patients with post-cardiac arrest syndrome and traumatic brain injury.
キーワード
post-cardiac arrest syndrome
traumatic brain injury
therapeutic hypothermia
oxidative stress
intensive care
発行日
2017-02
出版物タイトル
Acta Medica Okayama
71巻
1号
出版者
Okayama University Medical School
開始ページ
1
終了ページ
9
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
英語
著作権者
CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン
publisher
査読
有り
PubMed ID
Amo Type
Review
Submission Path
amo/vol71/iss1/1
JaLCDOI